TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 137 resultados LastUpdate Última actualización 05/06/2023 [10:40:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR IMPROVING THE ACCURACY OF GLUCOSE SENSORS USING INSULIN DELIVERY OBSERVATION IN DIABETES

NºPublicación: EP4183326A1 24/05/2023

Solicitante:

UNIV VIRGINIA PATENT FOUNDATION [US]

EP_3841968_PA

Resumen de: EP4183326A1

Method and System for providing a signal from an insulin pump, artificial pancreas, or another insulin delivery device as a source of information for improving the accuracy of a continuous glucose sensor (CGS). The effect of using insulin information to enhance sensor accuracy is most prominent at low blood glucose levels, i.e. in the hypoglycemic range, which is critical for any treatment. A system for providing a filtering/state estimation methodology that may be used to determine a glucose state estimate at time t-τ. The estimation may be extrapolated to some future time t and then the extrapolated value is used to extract the blood glucose component. The blood glucose component of the extrapolation and the output of the CGS are weighted and used to estimate the blood glucose level of a subject.

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GLUCOSE SENSOR

NºPublicación: EP4183331A1 24/05/2023

Solicitante:

MEDTRONIC MINIMED INC [US]

US_2023157598_PA

Resumen de: EP4183331A1

A method includes monitoring, via a device including an electrochemical cell, an electrical current that is proportional to an impedance of the electrochemical cell, and responsive to determining that the electrical current satisfies a threshold, measuring, via the device, a plurality of impedances of the electrochemical cell corresponding to a plurality of frequencies. The method further includes determining a charge transfer conductance and a solution resistance based on the plurality of impedances at fewer than four of the corresponding plurality of frequencies and determining the presence of electrochemical interference based on the solution resistance and the charge transfer conductance. The method further includes outputting an alert based on the determination of the presence of electrochemical interference.

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METHODS AND SYSTEMS FOR ANALYZING GLUCOSE DATA MEASURED FROM A PERSON HAVING DIABETES

NºPublicación: FI3277180T3 23/05/2023

Solicitante:

HOFFMANN LA ROCHE
ROCHE DIAGNOSTICS GMBH

CN_107809943_A

Resumen de: WO2016161254A1

Methods and systems are disclosed analyzing a glucose level of a person having diabetes. The method, in at least one example, comprises receiving into a computing device a plurality of measured glucose values from a continuous glucose monitoring system coupled to a person having diabetes, analyzing the plurality of measured glucose values with a probability analysis tool on the computing device to determine a glucose threshold (g lc ), and a boundary (g ρ ) glucose value at a probability threshold where the person having diabetes requires at least a predetermined insulin dose, and comparing, with the computing device, the boundary glucose value (g ρ ) to the glucose threshold (g lc ), wherein if the boundary glucose value (g ρ ) is greater than the glucose threshold (g lc ) then the computing device performs an alert on a user interface.

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SYSTEMS, DEVICES, AND METHODS FOR ANALYTE MONITORING

NºPublicación: WO2023086632A1 19/05/2023

Solicitante:

ABBOTT DIABETES CARE INC [US]

Resumen de: WO2023086632A1

A glucose monitoring system comprising a sensor control device comprising an analyte sensor coupled with sensor electronics, the sensor control device configured to transmit data indicative of an analyte level of a subject, and a reader device. The reader device comprises a wireless communication circuitry configured to receive the data indicative of the analyte level and a glycated hemoglobin level for the subject, a non- transitory memory, and at least one processor communicatively coupled to the non- transitory memory and the analyte sensor and configured: calculate a plurality of personalized glucose metrics for the subject using at least one physiological parameter and at least one of the received data indicative of the analyte level or the received glycated hemoglobin level, and a display, on a display of the reader device, a report comprising a plurality of interfaces including at least two or more of the received data indicative of the analyte level, the received glycated hemoglobin level, or the calculated plurality of personalized glucose metrics, wherein the plurality of interfaces comprising the report are based on a user type.

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CALIBRATION OF A SYSTEM FOR MONITORING GLUCOSE

NºPublicación: WO2023086232A1 19/05/2023

Solicitante:

MEDTRONIC MINIMED INC [US]

US_2023148916_PA

Resumen de: WO2023086232A1

In some examples, a system for monitoring glucose includes processing circuitry and a glucose monitor comprising one or more monitor electrodes and one or more working electrodes, wherein a first chemistry stack is disposed on at least one of the monitor electrode(s) and a second chemistry stack is disposed on at least one of the working electrode(s). The processing circuitry may be configured to measure one or more calibration values of an operating parameter of the monitor electrode(s), retrieve one or more pre-calibration values of the operating parameter of the monitor electrode(s), wherein the pre-calibration value(s) were measured before the calibration value, determine one or more delta values using the calibration value(s) and the pre-calibration value(s), and calibrate glucose values sensed by the working electrode(s) using the delta value(s).

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PRESERVED FORMULATIONS

NºPublicación: WO2023086980A1 19/05/2023

Solicitante:

LILLY CO ELI [US]

Resumen de: WO2023086980A1

Described herein are preserved formulations of insulin-Fc fusions. The formulations include insulin-Fc fusions having prolonged pharmacokinetic and pharmacodynamic profiles sufficient for once weekly administration in the treatment of diabetes and are sufficiently stable to allow for storage and use without unacceptable loss of chemical or physical stability.

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METHOD AND SYSTEM FOR DETERMINING RISK DATA CONCERNING INJURY IN A USER'S FOOT

NºPublicación: WO2023084453A1 19/05/2023

Solicitante:

PONTIFICIA UNIV JAVERIANA [CO]

Resumen de: WO2023084453A1

The present invention relates to a method and system for determining risk data (1) concerning injury in a user's foot, for designing and developing customised insoles for the early management of biomechanical alterations in diabetic patients, supported by a telemedicine platform and 15 embedded digital modules with protocols and software applications, for acquiring and integrating patient information by means of commercial specialised electronic devices integrated into the platform and which provided step-by-step assistance to an expert (8) for the smart automated design and remote production of customised therapeutic insoles adapted to the size and morphology of each user with diabetic foot syndrome.

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DEVICE FOR DELIVERING MEDICAMENT WITH INTEGRATED INFUSION CATHETER AND CONTINOUS GLUCOSE MONITOR SENSOR ASSEMBLY

NºPublicación: WO2023086482A1 19/05/2023

Solicitante:

AITA BIO INC [US]

Resumen de: WO2023086482A1

A device for delivering medicament to a user is disclosed. The device comprises a reservoir for storing medicament; an infusion catheter fluidly communicating with the reservoir to deliver the medicament into a subcutaneous layer of the user; a pump fluidly communicating with the reservoir and infusion catheter for pumping the medicament from the reservoir though the infusion catheter; an introducer needle movable within the infusion catheter, the introducer needle configured to facilitate (a) insertion of the infusion catheter into a subcutaneous layer of the user and (b) retraction of the introducer needle after insertion of the infusion catheter to enable delivery of medicament through the infusion catheter; and a sensor for continuously monitoring glucose level in the user, wherein the sensor is configured to (a) engage the introducer needle and/or the infusion catheter and (b) simultaneously advance along with the infusion catheter during the insertion into the subcutaneous layer of the user by the introducer needle.

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DELIVERY DEVICE WITH CAM DRIVEN PERISTALTIC PUMP

NºPublicación: AU2021358022A1 18/05/2023

Solicitante:

BECTON DICKINSON CO

CN_216536394_U

Resumen de: AU2021358022A1

A delivery device for delivering medicament, such as insulin, to a patient includes a housing and a base enclosing an inner cavity. Enclosed within the housing is a reservoir for containing a medicament, a delivery mechanism for delivering the medicament to the patient, and a pump in fluid communication with the reservoir and delivery mechanism. The base has an integrally formed fluid channel covered by a flexible membrane in fluid communication with the reservoir and the delivery mechanism. A peristaltic pump mechanism includes a cam assembly having a plurality of cams and cam follower assembly with a plurality of protrusions to sequentially engaging the flexible membrane to advance the fluid through fluid channel.

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SENSOR DEVICE MONITORS FOR CALIBRATION

NºPublicación: US2023148916A1 18/05/2023

Solicitante:

MEDTRONIC MINIMED INC [US]

WO_2023086232_A1

Resumen de: US2023148916A1

In some examples, a system for monitoring glucose includes processing circuitry and a glucose monitor comprising one or more monitor electrodes and one or more working electrodes, wherein a first chemistry stack is disposed on at least one of the monitor electrode(s) and a second chemistry stack is disposed on at least one of the working electrode(s). The processing circuitry may be configured to measure one or more calibration values of an operating parameter of the monitor electrode(s), retrieve one or more pre-calibration values of the operating parameter of the monitor electrode(s), wherein the pre-calibration value(s) were measured before the calibration value, determine one or more delta values using the calibration value(s) and the pre-calibration value(s), and calibrate glucose values sensed by the working electrode(s) using the delta value(s).

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Systems and methods for distributing continuous glucose data

NºPublicación: AU2023202651A1 18/05/2023

Solicitante:

DEXCOM INC [US]

JP_2023052229_PA

Resumen de: AU2023202651A1

The present disclosure relates to systems, devices and methods for receiving biosensor data acquired by a medical device, e.g., relating to glucose concentration values, and controlling the access and distribution of that data. In some embodiments, systems and methods are disclosed for monitoring glucose levels, displaying data relating to glucose values and metabolic health information, and controlling distribution of glucose data between applications executing on a computer, such as a smart phone. In some embodiments, systems and methods are disclosed for controlling access to medical data such as continuously monitored glucose levels, synchronizing health data relating to glucose levels between multiple applications executing on a computer, and/or encrypting data.

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A SYRINGE, A METHOD FOR MANUFACTURING SUCH SYRINGES AND AN ASSEMBLY

NºPublicación: US2023149639A1 18/05/2023

Solicitante:

MEDTECH CONCEPT LLC [US]

CN_115884805_PA

Resumen de: US2023149639A1

A syringe, having a front portion carrying a hollow, axially extending needle, a container, running from said front portion and forming a container rear end portion, a plunger, extending and being movable axially in the container, the needle rear end being in fluid connection with the container and the plunger being arranged to suck liquid, e.g. a liquid comprising insulin, through the needle when drawn away from the needle and to discharge liquid through the needle when pushed towards the needle, the plunger having a piston portion, turned to the needle rear end, and a coupling portion arranged to co-act with the piston portion for moving the piston portion in the container.

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ANALYTE SENSOR

NºPublicación: US2023148917A1 18/05/2023

Solicitante:

DEXCOM INC [US]

US_2022125355_A1

Resumen de: US2023148917A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

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Alarms and alerts for medication delivery devices and related systems and methods

NºPublicación: AU2023202630A1 18/05/2023

Solicitante:

BIGFOOT BIOMEDICAL INC [US]

US_2021401367_A1

Resumen de: AU2023202630A1

Systems, methods, and devices provide alarms and alerts in an on-body networked diabetes management system. Methods may include receiving glucose sensor data from a continuous glucose monitor and determining a dosage of insulin delivery based at least in part on the glucose sensor data. The method may include detecting an alarm or alert condition, and sending a wireless communication regarding the alarm or alert condition to a remote user-interface device. The method may include triggering an audible, visual, or haptic alarm or alert on the insulin delivery device unless an acknowledgement of the alarm or alert condition is received within a predetermined period of time.

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LIFESTYLE ACTIVITY DETECTION FOR DIABETES MANAGEMENT

NºPublicación: US2023148910A1 18/05/2023

Solicitante:

DIANAVI CORP [US]

WO_2021195610_A1

Resumen de: US2023148910A1

A lifestyle coaching system for lifestyle intervention in disease management is provided. The lifestyle coaching system detects a patient performing various lifestyle activities, such as a workout or stress-inducing activity, as part of determining and optimizing real time or near-real time coaching output that is displayed to a patient via a user device. The provided lifestyle coaching system is able to detect a start and end time of each of the patient's workouts despite receiving the patient's heart rate data at a low sampling rate from a fitness tracking device by combining the low sample rate heart rate data with secondary factors indicative of patient working out. The provided lifestyle coaching system is also able to detect when an elevated heart rate of a patient is due to stress rather than exercise.

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DYNAMIC DISPLAY OF GLUCOSE INFORMATION

NºPublicación: US2023154625A1 18/05/2023

Solicitante:

ABBOTT DIABETES CARE INC [US]

Resumen de: US2023154625A1

Method and system including displaying a first representation of a medication treatment parameter profile, displaying a first representation of a physiological profile associated with the medication treatment parameter profile, detecting a modification to a segment of the medication treatment parameter profile, displaying a modified representation of the medication treatment parameter profile and the physiological profile based on the detected modification to the segment of the medication treatment parameter profile, modifying an attribute of the first representation of the medication treatment parameter profile, and modifying an attribute of the first representation of the physiological profile are provided.

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ENCAPSULATION DEVICE SYSTEMS WITH OXYGEN SENSORS WITH OR WITHOUT EXOGENOUS OXYGEN DELIVERY

NºPublicación: AU2023202712A1 18/05/2023

Solicitante:

UNIV ARIZONA [US]

KR_20230037059_PA

Resumen de: AU2023202712A1

An encapsulation device system for therapeutic applications such as but not limited to regulating blood glucose. The system may comprise an encapsulation device with a first oxygen sensor integrated inside the device and a second oxygen sensor disposed on an outer surface of the device, wherein the sensors allow for real-time measurements (such as oxygen levels) related to cells (e.g., islet cells, stem cell derived beta cells, etc.) housed in the encapsulation device. The system may also feature an exogenous oxygen delivery system operatively connected to the encapsulation device via a channel, wherein the exogenous oxygen delivery system is adapted to deliver oxygen to the encapsulation device.

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KITS AND METHODS FOR MEASURING INSULIN SENSATIVITY

NºPublicación: EP4178440A1 17/05/2023

Solicitante:

UNIV LOUISIANA STATE [US]

WO_2022011345_PA

Resumen de: WO2022011345A1

This invention is directed to towards methods of identifying a subject with insulin resistance. For example, this invention is drawn to adjusting C-peptide urinary excretion rate for average glucose concentration to identify a subject with insulin resistance.

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THERAPEUTIC HYBRID MICRONEEDLE PATCH FOR THE DELIVERY OF INSULIN AND GLUCAGON

NºPublicación: EP4178606A1 17/05/2023

Solicitante:

THE REGENTS OF UNIV OF CALIFORNIA [US]

CN_115811985_PA

Resumen de: WO2022010698A1

A therapeutic hybrid microneedle patch mimics the inherent counter-regulatory effects of β-cells and α-cells for blood glucose management by dynamically releasing insulin or glucagon contained within the microneedles of the therapeutic hybrid microneedle patch. The two types of microneedles in the therapeutic hybrid microneedle patch share a co-polymerized matrix but comprise different ratios of the key monomers to be 'dually-responsive' to both hyper- and hypoglycemic glucose conditions. In a type 1 diabetic mouse model, the therapeutic hybrid microneedle patch effectively controls hyperglycemia while minimizing the occurrence of hypoglycemia in the setting of insulin therapy and simulated delayed meal or insulin overdose. In other embodiments, multiple patches are applied to achieve similar results.

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AUTONOMOUS MEDICAMENT DOSE TRIMMING

NºPublicación: WO2023081239A1 11/05/2023

Solicitante:

BETA BIONICS INC [US]

Resumen de: WO2023081239A1

A glucose level control system (GLCS) may be configured to determine a long-acting insulin dose recommendation based at least in part on a therapy of fast-acting insulin provided to a subject during a therapy period. The GLCS may be configured to operate in multiple operating modes with each operating mode configured to provide glucose control therapy for a different glycemic dysregulation condition (e.g., type-1 or type-2 diabetes). The GLCS may be configured to determine a recommended medicament dose based at least in part on therapy data and/or user-specified medicament related inputs, which may include qualitative meal announcements. The dose of medicament may be modified by the GLCS before the subject experiences a hypoglycemic event. The GLCS may generate a therapy management data set and perform a therapy management support process including generation of an excursion dosing threshold value or a backup therapy protocol.

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METHOD FOR OUTPUTTING MESSAGE SUGGESTING BEHAVIOR TO USER ON BASIS OF BLOOD GLUCOSE VALUES OF USER, AND ELECTRONIC DEVICE PERFORMING SAME

NºPublicación: WO2023080407A1 11/05/2023

Solicitante:

SAMSUNG ELECTRONICS CO LTD [KR]

Resumen de: WO2023080407A1

An electronic device according to an embodiment can generate logs of a user's blood glucose values obtained through a blood glucose sensor, determine a target event on the basis of the logs and a user's target blood glucose value obtained through the blood glucose sensor, and output a message suggesting a target behavior for the target event. Various other embodiments may be possible.

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ENZYME-FREE BLOOD GLUCOSE SENSOR AND MANUFACTURING METHOD THEREFOR

NºPublicación: WO2023080536A1 11/05/2023

Solicitante:

ULSAN NAT INST SCIENCE & TECH UNIST [KR]

Resumen de: WO2023080536A1

An enzyme-free blood glucose sensor and a manufacturing method therefor are disclosed. The enzyme-free blood glucose sensor comprises: a substrate; an insulating layer deposited and formed on the substrate; a porous carbon electrode deposited and formed on the insulating layer; a metal material region formed on at least a portion of the surface of the porous carbon electrode; and a palladium electrode deposited and formed on the insulating layer to be spaced apart from the porous carbon electrode, wherein in the palladium electrode, a negative voltage is applied to locally increase the concentration of hydroxide ions around the palladium electrode, and a current signal difference according to glucose concentration can be measured by using the metal material region, thereby measuring blood glucose.

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SENSING SYSTEMS AND METHODS FOR PROVIDING DIABETES DECISION SUPPORT USING CONTINUOUSLY MONITORED ANALYTE DATA

NºPublicación: WO2023081734A1 11/05/2023

Solicitante:

DEXCOM INC [US]

Resumen de: WO2023081734A1

Certain aspects of the present disclosure relate to methods and systems for predicting glycemic events in a patient induced as a result of physical activity. In certain aspects, a method includes monitoring a plurality of analytes of the patient continuously during a time period to obtain analyte data, the plurality of analytes including at least glucose and lactate. The method further includes processing the analyte data from the time period to determine an intensity level of physical activity engaged by the patient during the time period. The method further includes generating a glycemic event prediction using at least the analyte data for the plurality of analytes and the determination of physical activity intensity. The method further includes generating one or more recommendations for treatment for the patient based, at least in part, on the glycemic event prediction.

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SYSTEM AND METHOD FOR DATA ANALYTICS AND VISUALIZATION

NºPublicación: US2023146456A1 11/05/2023

Solicitante:

DEXCOM INC [US]

AU_2023202235_A1

Resumen de: US2023146456A1

Systems and methods are described that provide a dynamic reporting functionality that can identify important information and dynamically present a report about the important information that highlights important findings to the user. The described systems and methods are generally described in the field of diabetes management, but are applicable to other medical reports as well. In one implementation, the dynamic reports are based on available data and devices. For example, useless sections of the report, such as those with no populated data, may be removed, minimized in importance, assigned a lower priority, or the like.

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DEVICE FOR NON-INVASIVE BLOOD GLUCOSE CONCENTRATION MEASUREMENT

Nº publicación: US2023148312A1 11/05/2023

Solicitante:

GLUCOACTIVE SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA [PL]

WO_2022009071_PA

Resumen de: US2023148312A1

The subject of the invention is a device for non-invasive blood glucose concentration measurement, comprising a central control system (4), a scattering module (1) and an electronic control system (2) of the scattering module (1) connected to it. The electronic control system (2) of the scattering module (1) is connected to the central control system (4). The scattering module (1) comprises a detection element (28) and a coherent radiation source (14) connected to the control system of the coherent radiation source (13). The device is characterized in that it further comprises a transmission module (7) and an electronic control system (8) of the transmission module (7) connected to it, connected to the central control system (4). The device further comprises a proximity sensor (12), connected to the central control system (4). The device comprises an optical fiber probe (11) comprising an emitting optical fiber (15) and a measuring optical fiber (18). The emitting optical fiber (15) is connected to a coherent radiation source (14). The measuring optical fiber (18) is connected to a detection element (28). The emitting optical fiber (15) and the measuring optical fiber (18) are parallel to each other within the optical fiber probe (11). The emitting optical fiber (15) and the measuring optical fiber (18) have a numerical aperture larger or equal to 0.5.

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