CORONAVIRUS: DIAGNÓSTICO Y TERAPIA EN HUMANOS

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Resultados 370 resultados LastUpdate Última actualización 20/10/2020 [18:32:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 365 días/Published applications in the last 365 days



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Smart COVID Mask: AI-based mask with attachment to auto-detect and kill the COVID-19 virus

NºPublicación: AU2020102080A4 15/10/2020

Solicitante:

BALUSAMY BALAMURUGAN PROF [IN]
KALLAM SURESH DR [IN]
KUMAR ARVIND DR [IN]
MUTHIAH DEEPA DR [IN]
N GAYATHRI MS [IN]
S RAKESH KUMAR MR [IN]
SHANKAR LAKSHMI ENGR [IN]
SHARMA MEENAKSHI PROF [IN]
SHARMA REECHA DR [IN]
SHEKHAR JAYANT PROF [ET]

Resumen de: AU2020102080A4

Smart COVID Mask: Al-based mask with attachment to auto detect and kill the COVID-19 virus Abstract The eruption of Coronavirus disease 2019 (COVID-19), caused by critical acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), has killed a vast population and infected many in India and around the world, resulting in the greatest tragedy for humans. So there's an urgent need for preventive equipment like sanitizers, masks to prevent individuals from getting infected, as prevention is the only remedy for now. Apart from this, the technology can also help to fight against COVID-19 as nowadays advanced technologies are being used as a critical component in these types of scenarios. So here the proposed solution is a smart COVID Mask: Al-based mask to auto-detect and kill the coronavirus, that can detect the COVID-19 virus over any entry points of the face and sanitize it thoroughly to prevent it from entering the body. Smart COVID Mask: an Al-based mask that can auto-detect and kill the COVID-19 virus before it enters the body. The mask is equipped with sensors and disinfectant. The identified entry points of the COVID-19 virus are facial openings like nasal cavity, mouth & eyes. If we are able to kill the virus before it enters the body, then we can prevent further infection.AI-based scanner with a built-in optical Biosensor that detects the COVID-19 virus and then directs the sanitization module to kill it. 1| P a g e

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SaniClip: a unique combination of a therapeutic pump, bottle size and a novel clip/holster, that connects to a body worn dispenser that only one hand is required to dispense the solution using a pump technique and is always readily available.

NºPublicación: AU2020102149A4 15/10/2020

Solicitante:

DOCTORS OWN BRAND PTY LTD [AU]

Resumen de: AU2020102149A4

SaniClip - Single hand body worn fluid dispensing device With the recent upsurge in COVID-19 and other infections here has been a significant demand for a safe and reliable dispenser method for hand sanitizer and other disinfectants. Current dispensing techniques require two hands to dispense the solution and is not readily available to the user. The novel invention involves a unique combination of a therapeutic pump, bottle size and a novel clip/holster, that connects to a body worn dispenser that only one hand is required to dispense the solution using a pump technique and is always readily available. This will increase compliance, safety and infection prevention Figure 1 Side view Twist lock Pump Nozzle Full loop on clip 700 Main canisterr Belt clip

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METHOD AND SYSTEM FOR SCREENING FOR COVID-19 WITH A VOCAL BIOMARKER

NºPublicación: US2020323484A1 15/10/2020

Solicitante:

VOCALIS HEALTH [IL]

Resumen de: US2020323484A1

A computer-based method for screening unknown subjects for COVID-19, including steps of recording at least one voice clip from a screened subject, pre-processing the screened subject voice clip, computing a spectrogram of the pre-processed screened subject voice clip, extracting a feature vector from said screened subject spectrogram, applying a machine learning classifier of a COVID-19 vocal biomarker on the extracted screened subject feature vector thereby receiving a COVID-19 vocal biomarker value, and outputting that the screened subject is COVID-19 positive or COVID-19 negative, based on the COVID-19 vocal biomarker value. The step of extracting the feature vector employs a pre-trained deep convolutional neural network.

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DIAGNOSIS AND TREATMENT FOR CHRONIC INFLAMMATION AND VIRUS INFECTION

NºPublicación: WO2020200186A1 08/10/2020

Solicitante:

UNIV SUN YAT SEN [CN]

Resumen de: WO2020200186A1

The present application provides a diagnosis and treatment method for chronic inflammation. The technical solution provided by the present application is an application of a reagent in preparing a product for preventing and/or treating chronic inflammation diseases: the reagent is a substance for inhibiting the activity of an abnormal content of IFP35 and/ or NMI which is secreted outside the cell as an inflammatory factor. Experiments prove that using antibodies and the like to inhibit the activity of an abnormal content of IFP35 and/or NMI which is secreted outside the cell as an inflammatory factor can effectively treat chronic inflammation diseases. In the present application, IFP35 and/or NMI are also used as a target spot, providing a diagnosis/auxiliary diagnosis and treatment method and tool for infection of viruses, particularly novel coronavirus-19 (COVID-19).

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OLIGOPEPTIDES FOR QUANTITATIVE VIRAL PROTEOMIC ANALYSIS METHODS AND USES

NºPublicación: WO2020198865A1 08/10/2020

Solicitante:

UNIV BRITISH COLUMBIA [CA]

Resumen de: WO2020198865A1

Provided are purified oligopeptides, labelled oligopeptides, and stable isotope labelled oligopeptides, methods for their use in determining the maturation status of the flaviruses or coronaviruses in a human biological sample. The purified oligopeptides, labelled oligopeptides, and stable isotope labelled oligopeptides may also be used to measure the level of the flavirus protein or coronavirus protein in a human biological sample. Methods are also provided for treating a subject based on the maturation status of the flaviruses or the coronaviruses in the subject's biological sample and/or based on the level of the flavirus or coronavirus protein in the subject's biological sample.

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An electrical switch or button identifiable or marked by the words "COVID 19" or an abbreviation with the same meaning

NºPublicación: AU2020101989A4 08/10/2020

Solicitante:

DRLOCK 24H PTY LTD [AU]

Resumen de: AU2020101989A4

Abstract An electrical switch or button identifiable or marked by the words "COVID 19" or an abbreviation with the same meaning. The main function of the device is to be easily recognisable as a electrical trigger in the form of button or switch, and when triggered by a press or switching action will trigger an electrical circuit.

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METHOD OF INHIBITING OR REDUCING A CORONAVIRIDAE VIRUS INFECTION

NºPublicación: US2020317668A1 08/10/2020

Solicitante:

PTC THERAPEUTICS INC [US]

EP_3718405_A1

Resumen de: US2020317668A1

Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of inhibiting or reducing viral replication or the production of viral RNA or DNA or viral protein using such Compounds, and methods for treating viral infections, such as an RNA virus belonging to the family Coronaviridae, involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments.

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CORONAVIRUSES EPITOPE-BASED VACCINES

NºPublicación: US2020308232A1 01/10/2020

Solicitante:

UNIV RAMOT [IL]

US_2018334480_A1

Resumen de: US2020308232A1

Provided are polypeptides derived from the coronaviruses (CoVs) Spike protein (S) characterized by high affinity and specificity the S receptor and its neutralizing antibodies. Further provided are compositions and vaccines, and vaccine-based therapies targeting CoVs, and SARS and MERS viruses in particular.

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Smart COVID Kit: Designing Automatic Hand Sanitizer Dispenser and Temperature Checker for use during Pandemics

NºPublicación: AU2020101947A4 01/10/2020

Solicitante:

SHANMUGAM BALAMURUGAN DR [IN]

Resumen de: AU2020101947A4

2 Smart COVID Kit: Designing Automatic Hand Sanitizer Dispenser and Temperature 3 Checker for use during Pandemics 5 Abstract: 6 The Smart Sanitizer Dispenser (SSD) for COVID-19 scenario helps the customers/patients to 7 make use of the sanitizer in an automatic and contactless manner. Contactless sensor senses the 8 human hand. The temperature sensor senses the human hand temperature. Contactless and 9 temperature sensors are attached to SSD itself. The dispensor dispenses the sanitizer in an 0 automatic manner. The medical control unit monitors the temperature of the hamans which is in 1 seperate location. By using this SSD, customers/patients can make use of the sanitizer in an 2 automatic manner without touch the dispenser. 110 - Temperature Sensor 120 - Contactless Sensor 130 - Control Unit 2 Drawing 3- Prototype od Smart Sanitizer Dispenser

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METHODS AND COMPOSITIONS FOR TREATING VIRUS-ASSOCIATED INFLAMMATION

NºPublicación: US2020308262A1 01/10/2020

Solicitante:

UNIV MIAMI [US]

Resumen de: US2020308262A1

The compositions and methods described herein include methods and agents that inhibit inflammasome signaling in a mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s) or other agents. Also described herein are compositions and methods of use thereof for treating viral-associated lung inflammation, for example lung inflammation associated with viral infections such as SARS-CoV-2.

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SILVER NANOPARTICLES IMPREGNATED COVERS FOR ELECTRONIC DEVICES TO COMBAT NOSOCOMIAL INFECTIONS

NºPublicación: US2020306400A1 01/10/2020

Solicitante:

INFECTION SCIENCES LLC [US]

WO_2018156749_A1

Resumen de: US2020306400A1

An anti-microbial covering for use with electronic devices used in a healthcare environment is disclosed. The covering is impregnated during manufacturing with nano-sized silver particles and wrapped around the electronic device to stop the spread of nosocomial infections. The silver particles vary in shape and size to maximize the anti-microbial effects of each sheet, and each particle is sized to be less than 60 nanometers in diameter. The covering may be used in a process to disrupt nosocomial infections in a healthcare facility by having employees use the covering to cover electronic devices in the facility. The process includes a method for tailoring the anti-microbial covering to target specific pathogens present in the facility or, alternatively, tailor the covering to target pandemic level threats, such as for example the Covid-19 virus or seasonal influenza viruses.

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ANTIVIRAL PEPTIDES FOR TREATMENT OF THE MIDDLE EAST RESPIRATORY SYNDROME

NºPublicación: US2020306338A1 01/10/2020

Solicitante:

NAT GUARD HEALTH AFFAIRS [SA]
KING SAUD BIN ABDULAZIZ UNIV FOR HEALTH SCIENCES [SA]
KING ABDULLAH INTERNATIONAL MEDICAL RES CENTER [SA]

Resumen de: US2020306338A1

A peptide that binds to the Si spike protein of Middle East Respiratory syndrome coronavirus or MERS-CoV and a method for inhibiting infection of a subject exposed to or having MERS-CoV by administering the peptide.

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A METHOD AND REAGENTS FOR THE DIAGNOSIS OF SARS-COV-2

NºPublicación: EP3715847A1 30/09/2020

Solicitante:

EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG [DE]
UNIV BERLIN CHARITE [DE]

Resumen de: EP3715847A1

The present invention relates to a method for diagnosing a SARS-CoV-2 infection comprising the step of detecting the presence or absence of an IgA class antibody to SEQ ID NO1 in a sample from a subject, a method for the differential diagnosis of a coronavirus infection, a use of an IgA class antibody to SEQ ID NO1 for diagnosing a SARS-CoV-2 infection or for the differential diagnosis of a coronavirus infection, preferably for distinguishing between a SARS-CoV-2, MERS and NL63, 229E, OC43 and HKU1 infection, and a kit comprising a polypeptide comprising SEQ ID NO1 or a variant thereof, preferably coated to a diagnostically useful carrier and one or more, preferably all reagents from the group comprising an antibody to SEQ ID NO1, a washing buffer, a means for detecting the presence of an IgA class antibody, preferably a secondary antibody binding specifically to IgA class antibodies, preferably comprising a detectable label, and a dilution buffer.

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Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments

NºPublicación: US10787501B1 29/09/2020

Solicitante:

REGENERON PHARMA [US]

Resumen de: US10787501B1

The present disclosure provides antibodies and antigen-binding fragments thereof that bind specifically to a coronavirus spike protein and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., coronavirus infections).

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Method and system for using Bluetooth and other nearby-communications technologies to help governments and health agencies reduce the spread of novel corona viruses and other highly-contagious diseases, with user privacy and security central to the design

NºPublicación: US2020302452A1 24/09/2020

Solicitante:

PLATT TIMO [US]
KRUEGER STEPHAN [US]
ROSELLE BARBARA [US]
POKOS COMMUNICATIONS CORP [US]

US_2019132400_A1

Resumen de: US2020302452A1

A communications method is established enabling exposure notification, contact tracing and movement tracking by using Bluetooth or other nearby communications technology for communicating with nearby smartphones and mobile devices, and for data exchange both to alert participants of possible exposure to someone who they have recently been in contact with, and who has subsequently been positively diagnosed, or potentially diagnosed as having, a novel coronavirus or other highly contagious disease, and to trace and identify containers, packages, envelopes and other objects that may have been in contact with a person or object carrying or potentially carrying the virus or disease

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DNA ANTIBODY CONSTRUCTS FOR USE AGAINST MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS

NºPublicación: US2020299359A1 24/09/2020

Solicitante:

WISTAR INST [US]
INOVIO PHARMACEUTICALS INC [US]

WO_2019067671_PA

Resumen de: US2020299359A1

Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to a Middle East Respiratory Syncytial Coronavirus (MERS-CoV) viral antigen. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating an MERS-CoV virus infection in a subject using said composition and method of generation.

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Smart COVID Scanner: Portable and Affordable Scanner to Detect COVID-19 Virus

NºPublicación: AU2020101728A4 17/09/2020

Solicitante:

BALUSAMY BALAMURUGAN PROF [IN]
CHAUDHARY SUMIT DR [IN]
KALLAM SURESH DR [IN]
KUMAR ARVIND DR [IN]
KUMAR SUNIL DR [IN]
N GAYATHRI MS [IN]
SHANKAR LAKSHMI MR [IN]
SHARMA MEENAKSHI PROF [IN]
SHARMA REECHA DR [IN]

Resumen de: AU2020101728A4

Smart COVID Scanner: Portable and affordable scanner to detect COVID-19 virus Abstract The world is facing the situation of an outbreak of the most recent corona virus called COVID-19 that has impacted the entire humanity. So scientists and researchers from diverse backgrounds are continuously working together to fight against this very new type of virus. So there's an urgent need for preventive equipment like sanitizers, masks to prevent individuals from getting infected, as prevention is the only available cure for now. Apart from this, the technology can also help to fight against COVID-19 as nowadays advanced technologies are being used as a critical component in these types of scenarios. The proposed solution is a portable scanner that can detect the COVID-19 virus over any surface or person & warn the user prior to its spreading. The scanner works with micro bio scanner that captures/detects the virus just like electron microscope emits rays for detection of microorganism, in the same way, this bio scanner which is integrated with Al-based system detects the COVID particles and classifies the virus based on the past training about the texture, size, and shape of COVID droplets. This scanner can be a great tool against COVID-19 and can be used in a wide range of applications so as to prevent the further spreading of this deadly virus. 1| P a g e Smart COVID Scanner: Portable and affordable scanner to detect COVID-19 virus Diagram Smart COV IDScanner Portable and affordab

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METHOD FOR PRODUCING A PERMEABLE MATERIAL THAT FILTERS OUT HARMFUL PARTICLES AND PRODUCTS CREATED THEREFROM

NºPublicación: US2020289989A1 17/09/2020

Solicitante:

TRUTEK CORP [US]

Resumen de: US2020289989A1

A permeable material that allows air to easily pass through the interstices in any direction. The permeable material may be a cloth, a mesh, latex, rubber, or any polymer. The material is saturated with a water and/or alcohol based solution containing either a cationic or anionic agent, a disinfecting agent, and a biocide. The solvent on the permeable material is permitted to evaporate. What remains on the permeable material is the cationic or anionic agent and the biocide. This coated material is now surrounded by an electrostatic field. The electrostatically charged material attracts oppositely charged particles and repels similarly charged particles. The particles that contain living organisms are inactivated by the biocide. The formulations have been shown to have efficacy against rhinovirus causing colds, influenza and corona viruses causing diseases such as swine flu and COVID-19, as well as other harmful airborne microscopic and sub-microscopic particles. The material may be formed into products such as face masks, unitary filters, and filtration devices. Users of these masks might want to periodically spray or otherwise apply the solution to the mask to restore its disinfecting, filtration, and biocidic properties. This would also render normally disposable cloth or surgical face masks reusable.

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Self-governed individual social safe determination and confirmation method and system

NºPublicación: US10777325B1 15/09/2020

Solicitante:

LI ZHAOYANG [US]

Resumen de: US10777325B1

The present invention provides a method, software program and a system for social safe determination and mutual identification such that individuals can meet and social with another with no or minimized risk exposure to COVID-19 virus or other infectious diseases through social or intimacy contact.

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Optical sensing and photocatalysis devices based on three-dimensional waveguiding structures and method of using same

NºPublicación: US10775560B1 15/09/2020

Solicitante:

SCIDATEK INC [US]

Resumen de: US10775560B1

In one embodiment, titanium dioxide absorbs ultraviolet light to generate an electron-hole pair which, in the presence of water and oxygen, generates radicals that react with and mineralize undesirable organic compounds, such as the lipid membranes that envelope and protect viruses such as Coronavirus Disease 2019 (COVID-19), allowing to pry apart the membranes and destroy the cells. Such photocatalysis devices can be used in airflow systems designed to circulate the air of essentially confined spaces through these devices to create air-disinfecting systems.

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COPPER ION COMPOSITIONS AND METHODS OF TREATMENT FOR CONDITIONS CAUSED BY CORONAVIRUS AND INFLUENZA

NºPublicación: US2020281972A1 10/09/2020

Solicitante:

CDA RES GROUP INC [US]

Resumen de: US2020281972A1

Provided herein are formulations containing copper ions and methods of treating underlying infections and conditions caused by coronavirus, particularly COVID-19, and influenzas, particularly influenza A and/or influenza B using such formulations. Methods of treating the underlying viruses and their resultant conditions using topical copper ion treatments are provided. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension may be combined with various carriers to form the copper ion treatment including creams or solutions. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.

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ANTI-COVID-19 (SARS-COV-2) VIRAL PHARMACEUTICAL COMPOSITION

NºPublicación: RU2731932C1 09/09/2020

Solicitante:

OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU KROMIS OOO KROMIS [RU]

Resumen de: RU2731932C1

FIELD: pharmaceutics.SUBSTANCE: invention refers to antiviral agents and concerns an anti-COVID-19 (SARS-CoV-2) viral pharmaceutical composition containing favipiravir which is presented in the form of film-coated tablets. Disclosed composition comprises: 43-44 % of micronised favipiravir with particle size of 40-50 mcm, 5.5-6.0 % sodium croscarmellose, 4.8-5.0 % povidone, 0.6-0.8 % magnesium stearate, 0.5-0.7 % of colloidal silica, 2.5-2.7 % of film shell and microcrystalline cellulose - the rest.EFFECT: said composition provides fast release of favipiravir from a dosage form (tablets).1 cl, 1 tbl, 3 ex

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METHODS AND COMPOSITION FOR IMPROVED ANTISEPSIS

NºPublicación: NL2025640A 04/09/2020

Solicitante:

VELOCE BIOPHARMA LLC [US]

Resumen de: NL2025640A

Disclosed are devices and methods for treating and disinfecting a surface that is also useful for the treatment of patients. Compositions, including antiseptic compositions, that can be used for the methods are also disclosed. In particular, invention provides an improved antiseptic With improved efficacy against COVID-19. One benefit of the disclosed methods and compositions is that it is effective even When used for very short contact times. The composition of the invention comprises an antiseptic and a cellulosic polymer.

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System and Method for Testing for COVID-19

NºPublicación: US2020279585A1 03/09/2020

Solicitante:

ROTHSCHILD RICHARD A [GB]

Resumen de: US2020279585A1

A method is provided for acquiring and transmitting biometric data (e.g., vital signs) of a user, where the data is analyzed to determine whether the user is suffering from a viral infection, such as COVID-19. The method includes using a pulse oximeter to acquire at least pulse and blood oxygen saturation percentage, which is transmitted wirelessly to a smartphone. To ensure that the data is accurate, an accelerometer within the smartphone is used to measure movement of the smartphone and/or the user. Once accurate data is acquired, it is uploaded to the cloud (or host), where the data is used (alone or together with other vital signs) to determine whether the user is suffering from (or likely to suffer from) a viral infection, such as COVID-19. Depending on the specific requirements, the data, changes thereto, and/or the determination can be used to alert medical staff and take corresponding actions.

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EXPRESSION VECTOR FOR CREATING IMMUNOBIOLOGICAL AGENT FOR INDUCING SPECIFIC IMMUNITY TO VIRUS OF SEVERE ACUTE RESPIRATORY SYNDROME SARS-COV-2 (EMBODIMENTS)

Nº publicación: RU2731356C1 01/09/2020

Solicitante:

FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE NATSIONALNYJ ISSLEDOVATELSKIJ TSENTR EPIDEMIOLOG [RU]

Resumen de: RU2731356C1

FIELD: biotechnology.SUBSTANCE: invention refers to biotechnology, immunology and virology. It concerns recombinant vectors which can be used in pharmaceutical industry for creation of immunobiological agent for induction of specific immunity against virus of severe acute respiratory syndrome SARS-CoV-2. Expression vector comprising a genome of a recombinant human adenovirus strain of 26serotype in which the E1 and E3 regions are deleted, and the ORF6-Ad26 region is replaced by ORF6-Ad5, with an inbuilt expression cassette selected from SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 (embodiment 1). Maternal sequence of human adenovirus of 26serotype is SEQ ID NO: 5. Furthermore, an expression vector comprising a genome of the recombinant strain of simian adenovirus of 25serotype in which the E1 and E3 regions are deleted, with an inbuilt expression cassette selected from SEQ ID NO: 4, SEQ ID NO: 2, SEQ ID NO: 3 (embodiment 2). Maternal sequence of simian adenovirus of 25serotype is SEQ ID NO: 6. Besides, an expression vector of a genome-containing recombinant human adenovirus strain of 5serotype in which E1 and E3 regions are deleted, with an inbuilt expression cassette selected from SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 (embodiment 3). Maternal sequence of human adenovirus of 5serotype is SEQ ID NO: 7. Method of using the developed expression vector for creating an immunobiological agent for inducing specific immunity to the virus of severe acute respiratory syndrome SARS-CoV-2

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