CORONAVIRUS: DIAGNÓSTICO Y TERAPIA EN HUMANOS

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Resultados 177 resultados LastUpdate Última actualización 16/01/2021 [17:31:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 120 días/Published applications in the last 120 days



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COVID-19 symptoms alert machine (CSAM) scanners

NºPublicación: US10888283B1 12/01/2021

Solicitante:

BENJAUTHRIT BOONSIENG [US]
BENJAUTHRIT SORAPOD B [US]
BENJAUTHRIT VATCHAREE L [US]
BENJAUTHRIT KAMOLCHANOK J [US]

Resumen de: US10888283B1

A COVID-19 Symptoms Alert Machine (CSAM) scanner, or apparatus, is described herein. This apparatus employs Artificial Intelligent (AI) technology in combination with the latest mobile device technology (viz. smart phone/smart watch) to quickly help track down people who have COVID-19 symptoms anywhere and anytime, isolate them, and professionally handle them, not allowing SARS-CoV-2 virus to spread. CSAM automatically measures body temperature and assesses lung conditions such as pulmonary fibrosis and B-lines (for asymptomatic people), and other current health vital information (CHVI), furnished by the participant, such as fever, sore throat, headache, and body ache to generate an alert signal when COVID-19 symptoms are found significant and to send it out to a COVID-19 control center. The alerted participant is then immediately required to go to the COVID-19 control center or be picked up by a special COVID-19 emergency vehicle for isolation and further evaluation and testing. If the testing turns out to be COVID-19 positive, the participant will be quarantined and treated appropriately according to COVID-19 protocol until he/she is tested COVID-19 negative. In the meantime, people who have been in close physical contact with this participant will be alerted and requested to be immediately checked for COVID-19 symptoms. If anyone is found to have COVID-19 symptoms, then he/she must go through the same protocol. The process is repeated until all people in the cluster are te

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VACCINES FORMED BY VIRUS AND ANTIGEN CONJUGATION

NºPublicación: US2021000942A1 07/01/2021

Solicitante:

KENTUCKY BIOPROCESSING INC [US]

Resumen de: US2021000942A1

Disclosed herein are methods of forming compounds and exemplary compounds in the nature of a conjugated compound, which in some embodiments comprises an antigen and virus particle mixed in a conjugation reaction to form a conjugate mixture, such that the conditions and steps of forming these products allow for use of the conjugate mixture as a vaccine, including but not limited to use as a vaccine against various pathogens including for treatment of diseases caused by novel coronaviruses (including SARS-COV 2).

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HANDHELD SENSOR FOR RAPID, SENSITIVE DETECTION AND QUANTIFICATION OF SARS-CoV-2 FROM SALIVA

NºPublicación: US2021003528A1 07/01/2021

Solicitante:

UNIV FLORIDA [US]

Resumen de: US2021003528A1

Various examples are provided for disposable medical sensors that can be used for detection of SARS-CoV-2 antigen, cardiac troponin I, or other biosensing applications. In one example, a medical sensing system includes single-use disposable test strip comprising a functionalized sensing area configured to detect SARS-CoV-2 antigen and a portable sensing and readout device including pulse generation circuitry that can generate synchronized gate and drain pulses for detection and quantification of SARS-CoV-2 antigen in biological samples. In another example, a method includes providing a saliva sample to a functionalized sensing area configured to detect SARS-CoV-2 antigen, generating synchronized gate and drain pulses for a transistor, the gate pulse provided via electrodes of the functionalized sensing area, and sensing an output of the transistor that is a function of a concentration of SARS-CoV-2 antigen in the sample.

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SYSTEM AND METHOD FOR DETECTION AND SORTING OF CELLS

NºPublicación: US2021001339A1 07/01/2021

Solicitante:

MICROSENSOR LABS LLC [US]

Resumen de: US2021001339A1

A system and method for detection of cells and sorting of cells are disclosed. Target cells, such as circulating tumor cells (CTCs) or antigen-specific antibody producing circulating memory B cells from COVID-19 patients, may be of interest. Magnetic beads may be bound to the target cells. After which, the bead-bound target cells may be identified using an applied magnetic field. In one example, magnetic sensors may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. In another example, an optical sensor may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. Further, separate from identification of the target cells, the bead-bound target cells may be sorted using an applied magnetic field. In this way, a magnetic field may be used for target cell identification and target cell sorting in order to detect and collect target cells of interest at the single-cell resolution.

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Personal Protective Face Shield for Preventing Biohazardous, Infectious or Pathological Aerosol Exposure (COVID-19)

NºPublicación: US2021001157A1 07/01/2021

Solicitante:

RASHAUD TARIQUE JIBRIL [US]
GOUDEAUX XAVIER JIBRIL [US]

Resumen de: US2021001157A1

This novel face shield/window is designed to provide all the protective qualities of traditional OSHA approved PPE face shields. Most critically, however, it also facilitates the creation of a protective Dynamic Ingress Barrier to prevent fine particles and bioaerosols from crossing the face shield plane and transport them away from the often breached and problematic periphery of mask/respirator protective zones. Integral to this process, the novel design enhances a particle's flocculant properties by disrupting the structural integrity of the corona virus electrostatic double layer, and reducing its electrokinetic potential before accelerating it into the airspace. Increasing its ability to flocculate with active viral aerosols, and subsequently settle out of the airspace for cleaning, or captive via a filter.

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Antiviral and virucidal nasal spray compositions and related treatment methods

NºPublicación: US10874650B1 29/12/2020

Solicitante:

FERRER MEDICAL INNOVATIONS LLC [US]

Resumen de: US10874650B1

Compositions for treatment or prevention of viral infections, such as influenza A and B, coronaviruses, including but not limited to COVID-19, and rhinoviruses, along with related treatment methods. Certain compositions according to preferred embodiments of the invention may comprise chlorpheniramine, xylitol, and other inactive ingredients, such as aloe vera and/or grapefruit seed extract.

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Highly active compounds against COVID-19

NºPublicación: US10874687B1 29/12/2020

Solicitante:

ATEA PHARMACEUTICALS INC [US]

Resumen de: US10874687B1

The present invention is the use of a small group of purine nucleotide phosphoramidate disclosed herein or a pharmaceutically acceptable salt thereof in an effective amount for the treatment or prevention of the novel 2019 coronavirus disease (COVID-19) in a host, for example a human, in need thereof.

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AN INTEGRATED SECURE COVIDE-19 CONTACT TRACING FRAMEWORK USING IOT PLATFORM WITH BLOCKCHAIN

NºPublicación: AU2020102965A4 24/12/2020

Solicitante:

GARG LALIT
CHUKWU EMEKA
NASSER NIDAL
CHAKRABORTY CHINMAY
GARG GAURAV

Resumen de: AU2020102965A4

AN INTEGRATED SECURE COVIDE-19 CONTACT TRACING FRAMEWORK USING IOT PLATFORM WITH BLOCKCHAIN Abstract The contact tracing process is inevitable approach which obverse required in the pandemic situation (COVID-19) to protect our human mankind. Unfortunately, health care centre from all over the world do not have unique feature and pattern to trace out the identify of infection carrying person. Nowadays, online digital marketing enters into all commercial business trades includes Gasari Bazaar, Education, Telemedicine, etc where it requires new model for data aggregation and sharing present to continue business transaction, thus, retain economic standard of the society. For smooth functioning of above-mentioned sectors, health care department should provide essential information about isolation zone, affected person area and continuous updating of infection count. Therefore, it is required the effective and user-friendly model of contact tracing approach which accompany patient privacy and health information security. Thereby, an integrated secure covide 19 contact tracing framework using IoT platform with blockchain technology is implemented to provide secured storage of patient's information and minimize the cost of scaling to existing contact tracing strategies. This model measures moving infection person count and protect the test result of voluntarily participation. RFID transceiver (proof-of-concept) involves tracking the moving test samples and record of test samples stor

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TREATMENT OF ACUTE MEDICAL CONDITIONS BY STIMULATING THE NEURAL ACTIVITY OF A NERVE SUPPLYING THE SPLEEN

NºPublicación: WO2020254797A1 24/12/2020

Solicitante:

GALVANI BIOELECTRONICS LTD [GB]

Resumen de: WO2020254797A1

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

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TREATMENT OF ACUTE MEDICAL CONDITIONS

NºPublicación: WO2020254793A1 24/12/2020

Solicitante:

GALVANI BIOELECTRONICS LTD [GB]

Resumen de: WO2020254793A1

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

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MICROPARTICLE COMPOSITIONS FOR TREATMENT OF INFECTION OR DISEASE, METHODS OF MAKING THE SAME, AND METHODS OF TREATING SUBJECTS WITH MICROPARTICLE COMPOSITIONS

NºPublicación: US2020397711A1 24/12/2020

Solicitante:

LEE GREGORY BRIAN [US]

Resumen de: US2020397711A1

Provided are microparticle compositions, methods of making the compositions, and methods of treating a subject with the present microparticle compositions by administering an effective amount of the microparticle composition for treating an infection or disease, to a subject in need thereof. The present microparticle compositions may include microparticles of essential oils, herbs, and/or supplements. By way of non-limiting example, the microparticle compositions may be particularly effective in the treatment of a Lyme tick borne illness related infection or disease, or a coronavirus, such as COVID-19. Also included are kits that include one or more of the present microparticle compositions and/or one or more components of the present compositions, and optionally one or more components, such as a device to aid in the delivery of the composition and/or instructions for administration.

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3D OBJECT CONTAINING CBD AND PRINTING OPERATING SYSTEM THEREFOR

NºPublicación: WO2020256371A2 24/12/2020

Solicitante:

BIO MEDICAL 3D PRINTING CO LTD [KR]

Resumen de: WO2020256371A2

The present invention relates to a printing operating system for a 3D object containing CBD, the 3D printing operating system of the present invention providing a printing operating method for a 3D object, whereby CBD-containing food, such as coffee, juice, syrup, sauce, ice cream, yogurt, chocolate, cookies, candy, etc., or CBD-containing products using a fluid, such as candles (scented candles), soap, cosmetics, oils, etc., are provided by being printed into various and distinctive shapes catering to consumer preferences, while quantitative control and verification are enabled so that the 3D object contains an amount of CBD which is legally allowed in each country. The 3D printing operating system (500) of the present invention implements a teleportation concept-based drug delivery method enabling contactless remote diagnosis and, at the same time, delivery of drugs such as CBD in an emergency situation such as the prevalence of coronaviruses (such as COVID-19) or various infectious diseases, and thus may become a useful CBD usage/delivery method to many users experiencing difficulties relating to tic disorders, sleep disorders, epilepsy in children and the alleviation of pain caused by various diseases.

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COMPENSATED SPLIT VENTILATOR CIRCUIT

NºPublicación: US2020398015A1 24/12/2020

Solicitante:

KEYSIGHT TECHNOLOGIES INC [US]

Resumen de: US2020398015A1

In response to the global shortages of medical ventilator due to emergence of COVID-19 pandemic, the expansion of ventilator availability can be realized by having a Compensated Split Ventilator Circuit fitted into a mechanical ventilator. Hence, a single ventilator may be shared by two patients simultaneously with moderately different lung resistances and compliances. The Compensated Split Ventilator Circuit enables for differential gas volume between two patients by adjusting the valves in the inspiratory and expiratory circuits to control the optimized amount of gas flow to each patient individually. Embodiments of the present invention may be implemented using off-the-shelf medical-grade components to ensure product durability and patient safety.

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TREATMENT OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS

NºPublicación: US2020397871A1 24/12/2020

Solicitante:

ANSUN BIOPHARMA INC [US]

US_2019262432_A1

Resumen de: US2020397871A1

The present disclosure provides novel compositions and methods for treating an infection by MERS-CoV. In particular, the present disclosure provides methods that entail administering agents having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by MERS-CoV.

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Systems and Methods For Internet-Of-Things (IOT) Robotic Sterilization Device

NºPublicación: US2020397936A1 24/12/2020

Solicitante:

ATOM INC [US]

Resumen de: US2020397936A1

An internet-of-things (IOT) robotic sterilization system that operates autonomously for use in the prevention of diseases, e.g., Coronavirus Disease 2019 (COVID-19), caused by pathogens such as coronavirus SARS-CoV-2 and other pathogens present within an interior space is described. A robotic sterilization device is communicatively coupled to the IOT base module via an IOT network, and includes a misting or fogging system fluidically coupled to a liquid reservoir, a sensor module including plurality of sensors, a controller, and a locomotion system. The robotic sterilization device navigates a path within the interior space while creating a disinfecting mist with the misting system, and may coordinate with other IOT-connected devices, such as the HVAC system, UV Vent sterilizers, scent dispensing appliances, and others to more efficaciously sanitize the interior space to protect humans by eliminating pathogens.

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19 Sterilization apparatus having monitor for covid- 19 diffusion protection

NºPublicación: KR102193257B1 22/12/2020

Solicitante:

주케이세이프

Resumen de: KR102193257B1

본 발명은 코로나 19 확산 예방을 위한 모니터가 구비된 소독장치에 관한 것이다. 본 발명은 방문자가 인적사항을 터치하여 입력할 수 있는 모니터와 상기 모니터의 하부와 결합되어 있는 상단커버와 상기 상단커버의 하부와 연결 형성되며, 전면커버와 후면커버가 서로 결합되어 이루어지는 사각 형상의 본체와 상기 전면커버에는 내부 기체를 외부로 배출되도록 하기 위해 형성되는 1개 이상의 분사구와 상기 본체의 하부를 결합하여 마감하는 트레이와 상기 트레이의 하부에는 이동을 하기 위하여 모서리 부분에 각각 결합되어 형성되는 이동수단과 상기 본체의 양측에 각각 형성되어 회동이 가능한 파지부와 상기 파지부의 하방에 형성되어 소정 공간의 수용부가 마련된 홀더부와 상기 본체의 내부에는 상기 은나노를 송풍에 의하여 상기 분사구를 통하여 외부로 분사시키는 송풍장치를 포함하는 것을 특징으로 한다.

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ANTI-SARS-COV-2 VIRAL AGENT ANTIPROVIR

NºPublicación: RU2738885C1 18/12/2020

Solicitante:

IVASHCHENKO ANDREJ ALEKSANDROVICH [RU]

Resumen de: RU2738885C1

FIELD: medicine; pharmaceutics.SUBSTANCE: invention relates to the field of medicine and pharmaceutics. Disclosed is the use of a pharmaceutical composition containing aprotinin as an active ingredient and excipients, as an antiviral agent for treating and preventing COVID-19.EFFECT: invention provides high antiviral activity in the treatment and prevention of COVID-19.4 cl, 4 ex

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DEVICE FOR ACUPUNCTURE AND MOXIBUSTION THERAPY AND USES THEREOF

NºPublicación: US2020390650A1 17/12/2020

Solicitante:

ZHANG XUNHUA [US]

WO_2020245804_A1

Resumen de: US2020390650A1

The present invention provides an acumoxa therapy device utilizing energy waves for preventing, alleviating or treating COVID-19 (SARS-CoV-2) coronavirus infection. In one embodiment, the device delivers energy in a non-invasive manner. In one embodiment, the device is configured to include an energy pin and one or more energy rings. In one embodiment, the device delivers sufficient energy to certain body parts such as acupoints to achieve an intervening and/or therapeutic effect. In one embodiment, the device can maintain or improve general health, or can alleviate or treat a subject with COVID-19 infection and one or more other conditions. In one embodiment, the present invention also discloses a system comprising the device and uses thereof.

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LACTOFERRIN FOR ORAL USE WITH ANTIVIRAL ACTION

NºPublicación: WO2020250209A2 17/12/2020

Solicitante:

SOFAR SPA [IT]

Resumen de: WO2020250209A2

The present invention relates to a composition comprising lactoferrin for oral use as an antiviral, preferably for use in the treatment of viral infections of the respiratory system and of symptoms or disorders deriving from, or relating to, said viral infections, preferably SARS-coronavirus viral infections (e.g. COVID-19).

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2,4,7-SUBSTITUTED-7-DEAZA-2'-DEOXY-2'-FLUOROARABINOSYL NUCLEOSIDE AND NUCLEOTIDE PRO-DRUGS AND USES THEREOF

NºPublicación: WO2020252380A2 17/12/2020

Solicitante:

SOUTHERN RES INSTITUTE [US]

Resumen de: WO2020252380A2

The present disclosure is concerned with 2,4,7-substituted-7-deaza-2'-deoxy-2'- fluoroarabinosyl nucleoside and nucleotide prodrugs that are capable of inhibiting viral infections and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), herpes simplex virus (HSV), human cytomegalovirus (HCMV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), 229E, NL63, OC43, HKU1, Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and severe acute respiratory syndrome coronavirus disease 2019 (SARS-CoV-2), using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS

NºPublicación: WO2020247665A1 10/12/2020

Solicitante:

UNIV EMORY [US]

Resumen de: WO2020247665A1

Compounds, compositions and methods for preventing, treating or curing a coronavirus, picornavirus, and/or Hepeviridae virus infection in human subjects or other animal hosts. Specific viruses that can be treated include enteroviruses. In one embodiment, the compounds can be used to treat an infection with a severe acute respiratory syndrome virus, such as human coronavirus 229E, SARS, MERS, SARS-CoV-1 (OC43), and SARS-CoV- 2. In another embodiment, the methods are used to treat a patient co-infected with two or more of these viruses, or a combination of one or more of these viruses and norovirus.

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METABOLIC SIGNATURES ASSOCIATED WITH DIAGNOSIS, DISEASE PROGRESSION, AND IMMUNOLOGICAL RESPONSE TO TREATMENT OF PATIENTS WITH COVID-19

NºPublicación: US2020386766A1 10/12/2020

Solicitante:

METABOLOMYCS INC [US]

Resumen de: US2020386766A1

A system and method for using new biomarkers to assess individual diseases, including, but not limited to, a patient's prognosis before and/or after being diagnosed with the disease. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and/or treat various diseases, including, but not limited to, COVID-19.

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PEPTIDE IMMUNOGENS AND A VACCINE COMPOSITION AGAINST CORONAVIRUS INFECTION COVID-19 USING PEPTIDE IMMUNOGENS

NºPublicación: RU2738081C1 07/12/2020

Solicitante:

FED BYUDZHETNOE UCHREZHDENIE NAUKI GOSUDARSTVENNYJ NAUCHNYJ TSENTR VIRUSOLOGII I BIOTEKHNOLOGII VEKT [RU]

Resumen de: RU2738081C1

FIELD: biotechnology.SUBSTANCE: presented are immunogenic peptides used as a component of a vaccine composition against coronavirus infection COVID-19, having structures presented in Fig. 1. Described is a vaccine for coronavirus infection COVID-19, containing various combinations of said peptides: peptide immunogens having amino acid sequences SEQ ID NO: 1, SEQ ID NO: 3 and SEQ ID NO: 5; or peptide immunogens having amino acid sequences SEQ ID NO: 2, SEQ ID NO: 4 and SEQ ID NO: 6; or peptide immunogens having amino acid sequences SEQ ID NO: 4 and SEQ ID NO: 6; or peptide immunogens having amino acid sequences SEQ ID NO: 4 and SEQ ID NO: 7. Said peptide immunogens are covalently bound in the form of conjugates with a carrier protein, and the mixture of said conjugates of peptide immunogens and carrier protein is sorbed on a pharmaceutically acceptable adjuvant.EFFECT: technical result of the invention is obtaining such peptide immunogens and vaccine compositions, which carry minimally required antigenic determinants to form a specific immune response in rabbits, ferrets and hamsters and induce the protective immunity against COVID-19.9 cl, 5 dwg, 4 tbl, 7 ex

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INHALED HEXAPEPTIDE FOR TREATING RESPIRATORY DISEASES ASSOCIATED WITH INTERLEUKIN-6

NºPublicación: RU2737799C1 03/12/2020

Solicitante:

FEDERALNOE GOSUDARSTVENNOE BIUDZHETNOE UCHREZHDENIE NAUKI NAUCHNYI TSENTR BIOMEDITSINSKIKH TEKH FEDE [RU]

Resumen de: RU2737799C1

FIELD: medicine.SUBSTANCE: group of inventions refers to medicine, namely to infectious and internal diseases, and aims to treat COVID-19. Hexapeptide of formula (I): H-Tyr-D-Ala-Gly-Phe-Leu-Arg-OH (I) or a pharmaceutically acceptable salt thereof is used in the treatment of a respiratory disease associated with interleukin-6, where the respiratory disease is COVID-19, by pulmonary administration to a mammal in need thereof. Also for treating respiratory disease associated with interleukin-6, where the respiratory disease is COVID-19, using an aqueous pharmaceutical composition containing said hexapeptide or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable adjuvant, by pulmonary administration to a mammal in need thereof. Furthermore, a method of treating respiratory disease associated with interleukin-6, where the respiratory disease is COVID-19, involves a stage of pulmonary administration of an effective amount of said hexapeptide or its pharmaceutically acceptable salt to a mammal in need thereof.EFFECT: using the group of inventions enables providing more effective prevention, reduction or elimination of the symptoms of respiratory disease associated with IL-6, where the respiratory disease is COVID-19.9 cl, 10 ex, 6 tbl, 4 dwg

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WIDE-SPECTRUM ANTIBACTERIAL PHARMACEUTICAL FORMULATIONS COMPRISING LYSOZYME AND METHODS OF USING THE SAME

Nº publicación: US2020376094A1 03/12/2020

Solicitante:

AYBAR ECOTECHNOLOGIES CORP [DO]

WO_2020240472_A1

Resumen de: US2020376094A1

A wide-spectrum antibacterial pharmaceutical formulation comprising lysozyme and methods of treatment to prevent or cure diseases of bacterial etiology. Excipients provided in the pharmaceutical formulation comprising lysozyme enhance the stability and efficacy of lysozyme for treating bacterial infections in a mammal. The pharmaceutical formulation comprising lysozyme does not produce harmful secondary effects on tissues or organs during prolonged treatment. The formulation can be used to treat bacterial infections of the skin, mucosal regions, and administered into the blood stream of a patient, including respiratory infections. The formulation is useful in treating bacterial infections, including those that occur along with viral infections, particularly viral infections with a respiratory component, including COVID-19.

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