Resumen de: EP3766978A1

New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (CRIPS) which are peptides derived from Bacillus thuringiensis (Bt) and their genes and endotoxins in combination with toxic peptides known as Inhibitor Cystine Knot (ICK) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (TMOF) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects.

Resumen de: EP3766347A2

The present invention relates to pesticidal mixtures comprising as active compound I an insecticidal active carboxamide derivative and at least one active compound II selected from a group M comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, allosteric nicotinic acetylcholine receptor activitaors, chloride channel activators, juvenile hormone mimics, homopteran feeding blockers, mit grow inhibitors, inhibitors of mitochondrial ATP synthase, uncouplers of the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, ecdyson receptor agonists, octamin receptor agonists, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis, ryanodine receptor modulators and other compounds as defined in the description, in synergistically effective amounts.The invention relates further to methods and use of these mixtures for combating and controlling insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant proparagation material, such as seeds.

Resumen de: WO2019177855A1

Compositions and methods for controlling plant pests are disclosed. In particular, novel insecticidal proteins having toxicity against Coleopteran and/or Lepidopteran insect pests are provided. Nucleic acid molecules encoding the novel insecticidal proteins are also provided. Methods of making the insecticidal proteins and methods of using the insecticidal proteins and nucleic acids encoding the insecticidal proteins of the invention, for example in transgenic plants to confer protection from insect damage, are also disclosed.

Resumen de: WO2019178042A1

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

Resumen de: WO2019178038A1

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and/or nematode pest populations and for producing compositions with insecticidal activity.

Resumen de: WO2019178296A1

Provided herein are methods and compositions useful in cellular rejuvenation, tissue engineering, and regenerative medicine. Compositions and methods for rejuvenating aged cells and tissues to restore functionality are disclosed. In particular, cells are rejuvenated by transient exposure to non-integrated mRNAs encoding reprograming factors to rejuvenate cells while retaining cells in a differentiated state.

Resumen de: WO2019174664A1

The invention relates to a fungal strain of the genus Trichoderma with the designation HSA12 and to compositions that contain said fungal strain or spores thereof. The invention further relates to the use of the fungal strain or spores thereof in different methods, for example in a method for promoting and/or stabilizing plant growth and/or for increasing the yields of cultivated plants, which methods comprise inoculating soil, roots and/or above-ground plant parts with the fungal strain or spores with compositions containing said fungal strain or spores thereof, in order, inter alia, to increase the efficiency of nutrient intake and to improve the stress tolerance of cultivated plants. The invention further relates to the use of the fungal strain or spores thereof in a method for improving the structure and health of the soil or for decontaminating or remediating soil or a body of water and in a method for stabilizing or reestablishing endangered or desired wild plant populations. The invention further relates to a set of primer pairs for amplifying microsatellite loci of the genome of the fungal strain in order to determine molecular markers and to identify the fungal strain, and to a method for determining the fungal strain.

Resumen de: WO2020039267A1

The preparation, composition, and method of use of an antibacterial formulation utilizing tannins, acceptable for agriculture and for use against bacterial and fungicidal diseases in plants. The composition is based on an organic matrix and may be balanced with dispersants, flocculants and humectants, and may be used against a wide range of agricultural bacterial diseases.

Resumen de: WO2020016193A1

The present invention relates to methods for controlling phytopathogenic fungi using biological control agents. More specifically, the invention relates to methods for controlling phytopathogenic fungi having a long incubation period. In particular, the methods according to the invention are particularly suited for controlling the causal agent of powdery mildew on grapes, the fungus Erysiphe necator.

Resumen de: WO2019236672A1

Methods for selecting a microbe for co-formulation with a carrier are provided. In some examples, the methods include identifying a microbe that comprises one or more dipicolinic acid (DPA) synthase genes, a microbe that expresses one or more DPA synthase proteins, and/or a microbe that produces DPA; and selecting the microbe for co-formulation with a carrier. The methods optionally include co-formulating the selected microbe with the carrier. In some examples, the methods include detecting one or more DPA synthase genes or one or more DpaA and/or DpaB proteins in a microbe. In other examples, the methods include detecting DPA in a microbe or medium containing a microbe, for example, utilizing a fluorescence assay. Microbial compositions including one or more microbes that comprise one or more DPA synthase genes, express one or more DPA synthase proteins and/or produce DPA are also provided.

Resumen de: CO2019007592A1

Proceso con el cual se puede estabilizar el extracto de hojas de tabacos no curadas, para ser usado como materia prima o para el desarrollo de productos en los siguientes sectores agrícola, industrial, energético, farmacéutico y consumo masivo, dado que por ser un producto natural se oxida con facilidad a temperatura ambiente. En este método se parte de la recolección del mismo, para ser estabilizado en un rango de ph entre 3 y 6, manteniendo algunas de las características fisicoquímicas de las hojas de tabaco no curadas durante un lapso de tiempo prolongado.

Resumen de: WO2019230183A1

[Problem] The present invention addresses the problem of providing a novel lactic acid bacterium or a processed product thereof. The present invention also addresses the problem of providing a method for growing the lactic acid bacterium or a processed product thereof, or use of the lactic acid bacterium or a processed product thereof. [Solution] The present invention provides bacterial cells of the lactic acid bacterium Enterococcus durans (E. durans) HS-08 strain or a processed product thereof. In addition, the present invention can exhibit an IgA production-accelerating action, immunostimulation, anti-allergic action, harmful microbe and/or pathogenic microbe growth-inhibiting action, mucosa-protecting action, short-chain fatty acid production-enhancing action, organic acid production-enhancing action, and GRP43 gene expression-increasing action, plant growth-adjusting action, plant lodging-preventing action, plant taste-adjusting action, animal growth-accelerating action, or animal autoimmunity improvement.

Resumen de: WO2019202050A1

The present invention discloses a mixture of compounds one being a pattern-triggered immunity inductor and the other being a systemic resistance inductor that improves plant defense mechanisms, in particular by providing a synergistic effect on the plant defense mechanisms. Further aspects of the invention are the use of said for activating plant resistance against pathogens, and a kit for providing an agricultural composition for use in seeds, crops and plants.

Resumen de: KR20210005459A

본 발명은 인삼 꽃봉오리(flower bud of Panax ginseng C. A. Meyer) 추출물을 유효성분으로 함유하는 항균 조성물에 관한 것으로서, 보다 상세하게는, 인삼 꽃봉오리의 에탄올 추출물을 유효성분으로 함유하는 광범위 항균 조성물에 관한 것이다. 본 발명의 광범위 항균 조성물의 유효성분으로서의 인삼 꽃봉오리 추출물은, 본 명세서의 실시예를 통해 증명된 바와 같이, 항균용 약학 조성물, 건강 기능 식품, 화장료 조성물, 동물 사료 조성물, 식품, 화장품 또는 동물 사료용 첨가물, 각종 세정제 및 각종 청결제 등의 용도로 사용할 수 있는 뛰어난 효과가 있다. 뿐만 아니라, 본 발명의 인삼 꽃봉오리 추출물은 열 안정성이 우수하고, pH 2의 산성조건 및 혈장 내에서도 활성의 손실이 나타나지 않아, 액상, 크림, 분말, 환, 정 등의 다양한 형태로 손쉽게 가공될 수 있어 제약 산업, 식품 산업, 축산업, 보건 산업 및 화장품 산업상 매우 유용하게 이용될 수 있다.

Resumen de: EP3461345A1

The present invention relates to products and methods for the prevention and amelioration of bacterial contamination and degradation (spoiling) of biological material, particularly foodstuffs. In particular, the invention provides a product comprising an envelope of material defining a lumen wherein the lumen contains bacteriophage covalently attached to a surface.

Resumen de: WO2019064243A1

Nodulisporic acids (NAs) comprise a group of indole diterpenes known for their potent insecticidal activities; however, biosynthesis of NAs by its natural producer, Hypoxylon pulicicidum (Nodulisporium sp.) is exceptionally difficult to achieve. The identification of genes responsible for NA production could enable biosynthetic pathway optimization to provide access to NAs for commercial applications. Obtaining useful quantities of NAs using published fermentations methods is challenging, making gene knockout studies an undesirable method to confirm gene function. Alternatively, heterologous gene expression of H. pulicicidum genes in a more robust host species like Penicillium paxilli provides a way to rapidly identify the function of genes that play a role in NA biosynthesis. In this work, we identified the function of four secondary-metabolic genes necessary for the biosynthesis of nodulisporic acid F (NAF) and reconstituted these genes in the genome of P. paxilli to enable heterologous production of NAF in this fungus.

Resumen de: WO2019084342A1

Methods and systems are provided for generating and utilizing a genetically engineered bacterium comprising a modification in glnD, wherein said modification is selected from the group consisting of: deletion of the entire gene, deletion of substantially the entire gene, deletion of an ACT domain, deletion of more than 50% of an ACT domain, deactivation of an ACT domain, and deactivation of an UTase domain.

Resumen de: WO2021007545A1

Disclosed are compositions comprising compounds of Formula (I) and compounds of Formula (II). Also disclosed are compositions containing compounds of Formula (I) or compounds of Formula (II), or combinations thereof and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the disclosure.

Resumen de: US2021007361A1

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

Resumen de: US2021010020A1

Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.

Resumen de: US2021007362A1

The present invention provides a preparation method of Beauveria bassiana (Bals.) Vuill microsclerotium and a formulation thereof, and an application of the formulation thereof, belonging to the technical field of microsclerotium formulation preparation; the Beauveria bassiana microsclerotium formulation is prepared by the following steps of: 1) mixing conidia of Beauveria bassiana with Tween 20 aqueous solution to obtain spore suspension; 2) inoculating the prepared spore suspension into a liquid induction medium for induction culture to obtain microsclerotium; 3) mixing the prepared microsclerotium with a padding for drying to obtain dried microsclerotium; 4) mixing the prepared dried microsclerotium with an auxiliary to obtain a microsclerotium formulation. The Beauveria bassiana microsclerotium formulation produced by the method has low production cost, strong product tolerance and good insecticidal activity, moreover, after rehydrated, the formulation may rapidly germinate hyphae and produce spores to infect pests.

Resumen de: US2021007363A1

Provided is a plant exudate, methods for obtaining a plant exudate by inducing the plant to secrete an exudate and systems for the collection of a plant exudate which include: one or more plant container including at least two discrete compartments each configured to accommodate a split root of a plant, the compartments being a root stimulating compartment including one or more input being in fluid communication with at least a source of a plant root stimulant, and a root exudate harvesting compartment, and a root exudate collection compartment in fluid communication with the root exudate harvesting compartment.

Resumen de: WO2021007280A1

Compositions and methods for modulating a microbiome are disclosed. In accordance with the instant invention, methods of modifying and/or modulating a microbiome (e.g., the composition of a microbiome) are provided. The methods of the instant invention comprise contacting the microbiome (e.g., the assemblage of organisms composing the microbiome) with a compound excreted by an organism (e.g., nematode), particularly an organism that naturally lives in or is part of the microbiome.

Resumen de: US2021009483A1

Methods and systems are provided for generating and utilizing a bacterial composition that comprises at least one genetically engineered bacterial strain that fixes atmospheric nitrogen in an agricultural system that has been fertilized with more than 20 lbs of Nitrogen per acre.

Resumen de: US2021007336A1

The present invention relates to a biological control composition comprising at least arthropod biological control agents and astigmatid mite eggs. The invention also relates to the use of astigmatid mite eggs as a nutrient source for arthropod biological control agents. The invention also relates to a biological control composition comprising at least one population of arthropod biological control agents, a nutrient source comprising astigmatid mite eggs, and optionally, a support and/or dissemination substrate. Finally, the present invention further relates to a method for rearing arthropods from astigmatid mite eggs as a nutrient source.