TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

Volver

Resultados 107 resultados LastUpdate Última actualización 20/03/2019 [16:44:00] pdf PDF




Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



Página1 de 5 nextPage   Mostrar por página


SENSOR MODEL SUPERVISOR FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM

NºPublicación: US2019076600A1 14/03/2019

Solicitante:
MEDTRONIC MINIMED INC [US]

Resumen de: US2019076600A1

An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.



traducir


 

TRANSCUTANEOUS ANALYTE SENSOR

NºPublicación: US2019076071A1 14/03/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019076071A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.



traducir


 

Application of Electrochemical Impedance Spectroscopy in Sensor Systems, Devices, and Related Methods

NºPublicación: US2019076068A1 14/03/2019

Solicitante:
MEDTRONIC MINIMED INC [US]

Resumen de: US2019076068A1

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.



traducir


 

MICROELECTRONIC SENSOR FOR NON-INVASIVE MONITORING OF BLOOD GLUCOSE LEVELS

NºPublicación: WO2019049034A1 14/03/2019

Solicitante:
EPITRONIC HOLDINGS PTE LTD [SG]

Resumen de: WO2019049034A1

A microelectronic sensor for non-invasive monitoring of glucose levels in blood is based on the combination of an open-gate pseudo-conductive high-electron mobility transistor and a Vivaldi antenna installed in the open gate area of the transistor. The sensor is capable of sensing sub-THz radiation produced by a body of a user, and comprises a heterojunction structure made of the layers of GaN/AlGaN single- or poly-crystalline semiconductor materials stacked alternately and a conducting channel comprising a two-dimensional electron gas (2DEG) or a two-dimensional hole gas (2DHG) formed at the interface between the GaN/AlGaN layers. The highest sensitivity of the sensor is achieved when the thickness of the top recessed layer (GaN or AlGaN) in the open gate area between the source and drain contacts is 5-9 nm and the surface roughness of this top layer is about 0.2 nm or less.



traducir


 

We Test: At-Home Urine Test for Health & Wellbeing

NºPublicación: AU2019100160A4 14/03/2019

Solicitante:
WE TEST PTY LTD

Resumen de: AU2019100160A4

A test strip adapted to detect and measure one or more parameters present in urine of a subject, wherein the test strip comprises: a plurality of test pads mounted on a surface of the test strip, each test pad impregnated with at least one chemical reagent, including: (i) a first test pad impregnated with 1.5mg tetramethylbenzidine and 25mg 2,5dimethylhexane-2,5-d ihyd roperoxide to detect or measure blood; (ii) a second test pad impregnated with 0.65mg 2,4-dichlorobenzene diazonium salt to detect or measure bilirubin; (iii) a third test pad impregnated with 25.5mg methoxybenzene diazonium salt to detect or measure urobilinogen; (iv) a fourth test pad impregnated with 9.25mg sodium nitroprusside to detect or measure ketones; (v) a fifth test pad impregnated with 0.3mg 3,3',5,5'tetraiodophenolsulphoephthalein to detect or measure protein; (vi) a sixth test pad impregnated with 9.1mg 2-aminobenzenesulfonamide and 0.46mg tetrahydrobenzoquinoline to detect or measure nitrite; (vii) a seventh test pad impregnated with 315mg glucose oxidase, 50.5mg peroxidase and 7mg potassium iodide to detect or measure glucose; (viii) an eighth test pad impregnated with 0.026mg methyl red and 0.435mg bromothymol blue to detect or measure pH levels; (ix) a ninth test pad impregnated with 0.7mg bromothymol blue to detect or measure dehydration; (x) a tenth test pad impregnated with 0.45mg N-Tosylalanin intoxilyzer to detect or measure white blood cells (WBC); (xi) an eleventh test pad impregnated w



traducir


 

METHOD AND APPARATUS FOR NON-INVASIVE GLUCOSE MEASUREMENT

NºPublicación: WO2019049126A1 14/03/2019

Solicitante:
CNOGA MEDICAL LTD [IL]

Resumen de: WO2019049126A1

An apparatus for monitoring blood glucose comprising an invasive component for invasively measuring blood glucose and a non-invasive component, including color image sensor(s) to generate images from absorption of light that traversed the tissue, to receive a body part and generate a non-invasive blood glucose reading. Processor(s) convert the images into a vector V associated with a particular at least one invasive blood glucose measurement gk1, form a regular learning matrix, λ, implement a noninvasive isolation mechanism of the tissue glucose level by unique association of the vector λ k with an invasive blood glucose level, determine a neural network from the learning set λ by pairing vectors into a branch and forming multiple branches into loops, wherein two vectors are paired if they have a pre-defined similarity in the blood glucose levels that each are associated with; and calibrate the neural network by having it pass at least one test.



traducir


 

MOBILE TERMINAL FOR MEASURING BLOOD GLUCOSE

NºPublicación: WO2019046995A1 14/03/2019

Solicitante:
CHEN YINFANG [CN]

Resumen de: WO2019046995A1

A mobile terminal for measuring blood glucose, comprising a mobile terminal body (1). The mobile terminal body (1) comprises a casing (11). A display screen (2) is provided at a front side of the casing (11). A circuit board and a battery are provided inside the casing (11). The casing (11) is provided with a blood glucose meter. The blood glucose meter comprises two measuring electrodes (3), a capacitance meter (4) and a microprocessor. One end of the measuring electrodes (3) is provided with a button (5) that is for contacting human skin and is connected to the casing (11). The other end is connected to a signal input end of the capacitance meter (4). A signal output end of the capacitance meter (4) is connected to a signal input end of the microprocessor. A data output end of the microprocessor is connected to a data input end of the display screen (2). When a user holds the casing (11) and uses their finger to contact and push the button (5), the blood glucose meter is activated and their blood glucose is measured. The display screen (2) can directly display blood glucose measurement results. The mobile terminal for measuring blood glucose is easy to use.



traducir


 

METHODS, SYSTEMS, AND DEVICES FOR CALIBRATION AND OPTIMIZATION OF GLUCOSE SENSORS AND SENSOR OUTPUT

NºPublicación: US2019076066A1 14/03/2019

Solicitante:
MEDTRONIC MINIMED INC [US]

Resumen de: US2019076066A1

A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.



traducir


 

METHODS, SYSTEMS, AND DEVICES FOR CALIBRATION AND OPTIMIZATION OF GLUCOSE SENSORS AND SENSOR OUTPUT

NºPublicación: US2019076070A1 14/03/2019

Solicitante:
MEDTRONIC MINIMED INC [US]

Resumen de: US2019076070A1

A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.



traducir


 

METHODS, SYSTEMS, AND DEVICES FOR CALIBRATION AND OPTIMIZATION OF GLUCOSE SENSORS AND SENSOR OUTPUT

NºPublicación: US2019076067A1 14/03/2019

Solicitante:
MEDTRONIC MINIMED INC [US]

Resumen de: US2019076067A1

A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.



traducir


 

APPARATUS, SYSTEMS, AND METHODS FOR DETERMINING AND DISPLAYING PRE-EVENT AND POST-EVENT ANALYTE CONCENTRATION LEVELS

NºPublicación: US2019076072A1 14/03/2019

Solicitante:
ASCENSIA DIABETES CARE HOLDINGS AG [CH]

Resumen de: US2019076072A1

Embodiments of the invention provide apparatus, systems, and methods wherein pre-event and post-event analyte concentration readings associated with an event are collected and processed to determine a numerical delta. The numerical delta may be displayed on a visual display to aid in a ready determination of the affect that the event (alone or in combination with medication and/or insulin dosages) had on the analyte concentration levels. Medication and/or insulin dosages may be displayed alongside the numerical delta to gauge immediate relationships between numerical delta, dosage, and/or an associated event. Apparatus and systems for calculating and displaying the numerical delta are described, as are other aspects.



traducir


 

ADJUSTING INSULIN DELIVERY RATES

NºPublicación: EP3453414A1 13/03/2019

Solicitante:
BIGFOOT BIOMEDICAL INC [US]

Resumen de: EP3453414A1

The present disclosure relates to a diabetes management system and a method for the same. The system includes a pump device and a controller, where the controller is in electrical communication with a drive system for controlling dispensation of insulin from an insulin cartridge. The controller, over a first diurnal time period, communicates electrical control signals to the drive system to cause insulin to be dispensed based on a baseline basal insulin rate that is stored. The controller also receives at least blood glucose data to control dispensation of insulin in amounts variable from the baseline basal insulin rate. Additionally, the controller modifies the baseline basal insulin rate that is stored for a second diurnal time period that is at least 20 hours after the first diurnal period, based on an amount of insulin actually dispensed during the first diurnal time period.



traducir


 

INSULIN FORMULATIONS COMPRISING POLYSORBATE 80

NºPublicación: EP3452079A1 13/03/2019

Solicitante:
ARECOR LTD [GB]

Resumen de: WO2017191464A1

According to the invention there is provided inter alia an aqueous liquid pharmaceutical formulation comprising insulin or an insulin analogue, ionic zinc, a chelating agent and polysorbate 80.



traducir


 

Machine-to-machine mobile health communications device for diabetes remote monitoring

NºPublicación: GB2566311A 13/03/2019

Solicitante:
IKHARE LTD [GB]

Resumen de: GB2566311A

An integrated machine-to-machine mobile health gateway communications device for diabetes remote monitoring is described. The communications device 30 is connectable to a plurality of different types of glucose meter 20 and the Internet. The device comprises a controller, a first communications interface for connecting to a glucose meter, the glucose meter being one of a plurality of different types of glucose meter to which the first communications interface can connect, and receiving blood glucose measurements from the connected glucose meter, a second communications interface 70 for connecting to the Internet and transmitting the received blood glucose measurements over the Internet to a remote server, a battery, for powering the medical communications device, and a motion sensor. The controller is operable to activate the communications device in response to the motion sensor detecting movement of the communications device. Other embodiments provide for intelligent selection of a communications channel for use by the second communications interface through the use of different communications protocols. In embodiments, the device may also connect to the internet through different first and second communications channels, the second can be selectively used when the first is unable to connect.



traducir


 

POLYHEDRAL OLIGOMERIC SILSESQUIOXANE-BASED HYBRID NANO-PROBE, AND SENSOR COMPRISING SAME

NºPublicación: WO2019045331A1 07/03/2019

Solicitante:
INDUSTRY ACADEMIC COOPERATION FOUNDATION DANKOOK UNIV [KR]

Resumen de: WO2019045331A1

The present invention relates to a polyhedral oligomeric silsesquioxane (POSS)-based hybrid nano-probe, and a non-enzymatic glucose sensor comprising the same. When a hybrid nano-probe of the present invention is used, the detection of glucose can be confirmed through a color change without using an enzyme.



traducir


 

METHOD AND APPARATUS FOR NON-INVASIVE GLUCOSE MEASUREMENT

NºPublicación: US2019069821A1 07/03/2019

Solicitante:
CNOGA MEDICAL LTD [IL]

Resumen de: US2019069821A1

An apparatus for monitoring blood glucose comprising an invasive component for invasively measuring blood glucose and a non-invasive component, including color image sensor(s) to generate images from absorption of light that traversed the tissue, to receive a body part and generate a non-invasive blood glucose reading. Processor(s) convert the images into a vector V associated with a particular at least one invasive blood glucose measurement gk1, form a regular learning matrix, λ, implement a noninvasive isolation mechanism of the tissue glucose level by unique association of the vector Vk with an invasive blood glucose level, determine a neural network from the learning set λ by pairing vectors into a branch and forming multiple branches into loops, wherein two vectors are paired if they have a pre-defined similarity in the blood glucose levels that each are associated with; and calibrate the neural network by having it pass at least one test.



traducir


 

Method and System for Providing Basal Profile Modification in Analyte Monitoring and Management Systems

NºPublicación: US2019070360A1 07/03/2019

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2019070360A1

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.



traducir


 

NEUROMODULATION FOR METABOLIC CONDITIONS OR SYNDROMES

NºPublicación: US2019069942A1 07/03/2019

Solicitante:
METAVENTION INC [US]

Resumen de: US2019069942A1

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.



traducir


 

ANALYTE SENSOR

NºPublicación: US2019069817A1 07/03/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019069817A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.



traducir


 

METHODS, DEVICES AND SYSTEMS FOR ESTIMATING NUTRITIONAL ELEMENT CONTENT IN FOODS

NºPublicación: WO2019046530A1 07/03/2019

Solicitante:
ROCHE DIABETES CARE INC [US]
ROCHE DIABETES CARE GMBH [DE]
HOFFMANN LA ROCHE [CH]

Resumen de: WO2019046530A1

Systems and methods are provided for improving nutritional element content estimates from one or more individuals and/or determining a therapy or treatment based on a nutritional element content estimate and improving diabetes management. The systems and methods include a therapy or treatment display based on at least one nutritional element content estimate and at least one proficiency index respectively assigned to an individual to improve accuracy and reliability when estimating nutritional element content in foods and/or therapy or treatment based therefrom.



traducir


 

METHODS AND DEVICE ARRANGEMENT FOR PHYSICAL ACTIVITY THRESHOLDS REDUCING RISKS OF DIABETES, CARDIOVASCULAR DISEASES, INFLAMMATIONS, DEMENTIA, CANCERS AND MORTALITY IN SEDENTARY SUBJECTS

NºPublicación: WO2019043292A1 07/03/2019

Solicitante:
GLEAP HEALTH TECH OY [FI]

Resumen de: WO2019043292A1

High blood levels of very low density lipoprotein lipids (VLDLs) and glycoprotein acyl (Glyc A) are known to increase risk of diabetes, cardiovascular diseases, inflammations, cognitive impairments, cancers and premature deaths in sedentary persons. The invention determines physical activity thresholds of daily steps and accelerations to reduce plasma concentrations of VLDLs and Glyc A. The method and device is an accelerometer recording and classifying numbers of steps and accelerations and comparing the person's steps and accelerations with those shown to reduce VLDLs and Gly A. The invention is characterized in that if the daily number of accleration maxima exceeds the given threshold of 2980 steps in the acceleration range 1.3 - 1.7 g, the person has performed physical activity, typically known to reduce circulating VLDLs and Glyc A.



traducir


 

Reconstitution device for IV fluids and method of use

NºPublicación: AU2017299427A1 07/03/2019

Solicitante:
CAREFUSION 303 INC

Resumen de: AU2017299427A1

A system is provided for storage and reconstitution of IV solutions. The system may include one or more storage and reconstitution devices each configured to store and manipulate IV solution containers containing IV solutions in crystalline form that include hydration chemicals and therapeutic drugs. Crystalline hydration chemicals may include crystalline salts and sugars. The containers may be dimensionally precise enough for mechanical manipulation and configured such that sharp objects such as needles are not needed for fluid delivery to or from the container. Each storage and reconstitution device may store stacked containers and may include components for retrieval of a container from the storage and for reconstitution of the contents therein using a sterile water source within the device. IV doses may be manufactured, under appropriate standards, that can be mechanically reconstituted to produce high-quality doses in real time on the patient care unit or in the pharmacy.



traducir


 

SYSTEM AND METHOD FOR DETECTING APPLIED FORCE DURING INJECTION

NºPublicación: WO2019046436A1 07/03/2019

Solicitante:
BECTON DICKINSON CO [US]

Resumen de: WO2019046436A1

A medical device (100) includes an insulin pen (102), a pen needle (104) and a force sensor (106). The device also includes a microprocessor (206) to receive a signal from the force sensor (106). Audible and/or visual indicators (218, 220) provide feedback to a user to encourage proper injection technique. The device may also include an adaptor assembly comprising a sensor housing (306) and a first sensor (304) within the sensor housing, and a transfer needle assembly (308), the transfer needle assembly providing a connection (310) for a pen needle, and providing a fluid conduit between the pen needle (312) and the insulin pen (302). A second force sensor (314) is associated with a thumb button of the insulin pen (302).



traducir


 

GLUCOSE SENSOR AND METHOD FOR MANUFACTURING SAME

NºPublicación: WO2019045232A1 07/03/2019

Solicitante:
DONGWOO FINE CHEM CO LTD [KR]

Resumen de: WO2019045232A1

The present invention relates to a method for manufacturing a glucose sensor. The present invention comprises: an electrode forming step of forming an electrode part composed of a plurality of electrodes on a substrate; an electrode protection/electron transport function layer forming step of forming an electrode protection/electron transport function layer including an electrode protector and an electron transporter on the electrode part; a glucose reaction part forming step of forming a glucose reaction part on the electrode protection/electron transport function layer; and an ion exchange membrane forming step of forming an ion exchange membrane on the glucose reaction part. According to the present invention, the number, time, and cost of the processes required to manufacture a glucose sensor can be reduced.



traducir


 

SYSTEMS, METHODS, APPARATUSES AND DEVICES FOR DRUG OR SUBSTANCE DELIVERY

Nº publicación: WO2019043702A1 07/03/2019

Solicitante:
TRIPLE JUMP ISRAEL LTD [IL]
BEN DAVID YISHAI [IL]
SALOMON KFIR [IL]
YODFAT OFER [IL]
SHINAR GUY [IL]

Resumen de: WO2019043702A1

Embodiments of the present disclosure are directed to miniature insulin patch pump, assistance devices (e.g., for reservoir filling and /or cannula insertion), and methods related thereto. For example, in some embodiments, a substance/drug-delivery patch pump is provided and includes a reusable part (RP) including a power source, a driving mechanism, and an electronic module, and a disposable part (DP), where the disposable part can include at least a plurality of an adhesive base, a reservoir, a dosing mechanism, and a cannula.


traducir



 

Página1 de 5 nextPage Mostrar por página

Volver