TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 101 resultados LastUpdate Última actualización 22/09/2017 [17:46:00] pdf PDF




Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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Methods and Systems for Controlling an Infusion Pump

NºPublicación: US2017266381A1 21/09/2017

Solicitante:
DEKA PRODUCTS LP [US]

Resumen de: US2017266381A1

A system for pairing a controller and an infusion pump is disclosed. The system includes an infusion pump, a controller device and a user interface residing on both the infusion pump and the controller. The user interface includes a pairing mode for enabling wireless communication between the infusion pump and the controller device, wherein the user interface requires both the infusion pump and the controller to be in the pairing mode simultaneously. Also, a method of changing a power source in an infusion pump is disclosed. The method includes placing the infusion pump in idle mode wherein the infusion pump stops delivery. Removing the first power source from the infusion pump. Replacing the first power source with a second power source in the infusion pump, and maintaining the insulin on board during the changing of the first power source with the second power source.



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Analyte Monitoring Devices and Methods Therefor

NºPublicación: US2017269023A1 21/09/2017

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2017269023A1

Method and apparatus for performing a discrete glucose testing and bolus dosage determination including a glucose meter with bolus calculation function are provided.



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Compositions and Methods For Treating Joints

NºPublicación: US2017266221A1 21/09/2017

Solicitante:
DEPUY SYNTHES PRODUCTS INC [US]

Resumen de: US2017266221A1

Compositions and methods are disclosed for the treatment of osteoarthritis. The compositions comprising combinations of hyaluronic acid, glucosamine, and chondroitin sulfate, can be useful for any synovial joint, including the knee, shoulder, hip, ankle, hands, spinal facet, or temporomandibular joint, both for the relief of pain and for slowing disease progression.



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ANTHRACENYL-TETRALACTAM MACROCYCLES AND THEIR USE IN DETECTING A TARGET SACCHARIDE

NºPublicación: US2017266321A1 21/09/2017

Solicitante:
UNIV OF BRISTOL [GB]

Resumen de: US2017266321A1

wherein R9 and R10 are suitably hydrophilic substituents, which may be used to selectively bind to a target saccharide such as glucose and which exhibits a detectable spectroscopic response to such binding, thus enabling its use in the detection and correction of blood glucose concentrations in vivo.



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DIABETES TESTING KIT AND METHODS FOR ITS USE

NºPublicación: US2017265958A1 21/09/2017

Solicitante:
MEDICAL MONOFILAMENT MFG LLC [US]

Resumen de: US2017265958A1

Methods and apparatuses for use in screening for and assessing neuropathies, such as severe diabetic neuropathies of the feet, also known as Loss of Protective Sensation (“LOPS”). The methods and apparatuses described herein employ a kit including one or more of an insert having at least one testing instrument attached thereto, the at least one testing instrument comprising at least a holder and a monofilament; an enclosure including inner compartments for holding and securing the insert; a folder having one or more pockets for securing the insert and one or more of a mirror, a packet and other material, such as instructions. The apparatuses safely secure and protect the testing instrument(s) so that the risk of breaking or otherwise damaging the testing instruments during storage and/or shipping is significantly reduced. The methods and apparatuses are easy and low cost to manufacture, easy to use, scalable, and allow users to self-screen/test for, among other things, severe diabetic neuropathies of the feet.



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METHOD AND SYSTEM FOR PROVIDING BASAL PROFILE MODIFICATION IN ANALYTE MONITORING AND MANAGEMENT SYSTEMS

NºPublicación: US2017266380A1 21/09/2017

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2017266380A1

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.



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Superfast Sequential and Alternate Dual Wavelength Reflection Technique

NºPublicación: US2017265787A1 21/09/2017

Solicitante:
AIRWARE INC [US]

Resumen de: US2017265787A1

Two coherent narrow bandwidth infrared beams, the Signal and the Reference, are incident at an angle and at high frequency sequentially and alternately at the same spot of a whole blood/body tissues sample. The Signal beam has a center wavelength which falls within an absorption line of glucose in whole blood (e.g. 1.409μ). The Reference beam has a center wavelength which does not coincide with any known absorption lines of glucose in whole blood (e.g. 1,278μ). Radiation emitted from the spot at which the beams penetrate into the sample and subsequently emanate from it after multiple scattering and spurious absorption effects is collected by a lens onto an infrared detector. The ratio of the voltage detected from the emerging Signal beam over that of the Reference beam is processed to yield the value of glucose concentration in the whole blood/body tissue sample.



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DRUG-SOLUTION ADMINISTRATION DEVICE

NºPublicación: EP3219344A1 20/09/2017

Solicitante:
TERUMO CORP [JP]

Resumen de: EP3219344A1

To provide an insulin pump that introduces an appropriate amount of drug solution into a living body to allow a user (patient) to obtain sufficient efficacy. An insulin pump 100 includes an injection unit (a disposable injection unit 110), a delivery unit 120 (a disposable delivery portion 120A and a reusable delivery portion 120B), a detection unit 140, and a control unit 150. The control unit restricts a delivery device (a delivery device 122) 's operation of filling insulin S in a delivery member (a delivery tube 121) or an injection member (a cannula 111) and/or operation of administering the insulin into a living body, on the basis of a detection result of the detection unit.



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Method and Apparatus for Correction of Non-Invasive Blood Glucose Measurement

NºPublicación: EP3217876A1 20/09/2017

Solicitante:
IISM INC [KR]

Resumen de: KR101716663B1

The present invention relates to a method and a device to correct the non-invasive measurement of blood glucose, capable of correcting a blood glucose signal measured from an image of white light reflected from skin. The present invention provides a method and a device to accurately measure blood glucose by extracting a fundamental blood glucose signal. The method includes: a step of emitting white light to skin by using a white light source; a step of filtering the white light, reflected from the skin, through first and second wavelength filters; a step of obtaining a first signal, including a blood glucose signal and a pulse signal, based on an image generated by the white light filtered through the first wavelength filter; a step of obtaining a second signal, including a pulse signal, based on an image generated by the white light filtered through the second wavelength filter; a step of obtaining the blood glucose signal by deducting the second signal from the first signal; and a step of calculating blood glucose contents in subcutaneous blood vessels based on the obtained blood glucose signal. According to the disclosed method and device, blood glucose is able to be measured without a method of collecting a fundamental blood glucose signal in real time.



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Time averaged basal rate optimizer

NºPublicación: AU2017219138A1 14/09/2017

Solicitante:
DEXCOM INC

Resumen de: AU2017219138A1

TIME AVERAGED BASAL RATE OPTIMIZER Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated. BASAL RATE PROFILE 200 OPTIMIZATION PROVIDE A PROGRAMMED BASAL RATE PROFILE UPDATE PROGRAMMED BASAL RATE PROFILE, PERIODICALLY OR INTERMITTENTLY OPTIONALLY DYNAMICALLY ADJUST UPDATED PROGRAMMED BASAL RATE IN REAL TIME



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INJECTION PUMP CONTROL METHOD, CONTROL UNIT, AND INJECTION PUMP

NºPublicación: US2017258992A1 14/09/2017

Solicitante:
ZENSUN (SHANGHAI) SCIENCE & TECH CO LTD [CN]

Resumen de: US2017258992A1

Disclosed herein are method for controlling an insulin injection pump, a related control unit, and an injection pump. The control unit comprises an expected plasma insulin concentration value acquiring module, a current subcutaneous and interstitial insulin concentration value acquiring module, a supposed injection value acquiring module, an injection instruction sending module, and a counting module. The injection pump comprises a pump body and the control unit. The control unit is disposed in the pump body.



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Diabetes Control Using Postprandial Feedback

NºPublicación: US2017258395A1 14/09/2017

Solicitante:
NATH RATTAN [US]
VYAS SHEFALI [US]

Resumen de: US2017258395A1

Disclosed is a postprandial glucose-measuring device for preventing the development of or reversing T2D. Included are methods for using the device as well as better use for invasive and noninvasive glucose meters. Further disclosed are novel exercise-sensitizing compositions useful for managing blood glucose levels in Type-2 diabetics with minimal risk of hypoglycemia. The disclosed glucose meters allow a user to also measure exercise and meal size—all with relatively instant feedback—more effectively than having to track the complexity posed by labels, glycemic index and calories. Also disclosed is integration of glucose-measuring devices with smartphones and health monitoring technology to make possible safe and effective interpretation of postprandial glucose readings by a patient to control or reverse Type-2 diabetes.



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DIRECT INFRARED ANALYSIS OF POST-TRANSLATIONAL MODIFICATION OF PROTEINS

NºPublicación: WO2017153359A1 14/09/2017

Solicitante:
UNIV GENT [BE]

Resumen de: WO2017153359A1

The present invention relates to a method for measuring post-translational modification of proteins in a subject. The method comprises recording of infrared radiation within a predetermined wavenumber range, attenuated by an integument of said subject, wherein said integument is still attached to said subject, and comparing said attenuation of infrared radiation to a predetermined value for deriving information regarding post-translational modification of proteins in the integument. The invention also relates to a corresponding system as well as to a post-translational modified integument protein as marker for in vivo diagnosis of a disease, e.g. diabetes mellitus or renal insufficiency.



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ANALYTE MEASURING PATCH

NºPublicación: WO2017153506A1 14/09/2017

Solicitante:
ROCHE DIABETES CARE GMBH [DE]
F HOFFMANN-LA ROCHE AG [CH]
ROCHE DIABETES CARE INC [US]

Resumen de: WO2017153506A1

Disclosed is an analyte measuring patch for invasive measuring a concentration of an analyte, in particular glucose. The analyte measuring patch includes a sensor with a working electrode (101), a counter electrode (103) and a reference electrode (102). The patch further includes an electronics unit with a microcontroller (1200) and a current measurement unit. The microcontroller (1200) includes a control output (DAC), a first analogue input (ADC-1) and a second analogue input (ADC-2). The control output (DAC) is operatively coupled with a control electrode, the control electrode being either of the working electrode or (101) or the counter electrode (103). The first analogue input (ADC-2) is operatively coupled with a measurement electrode via the current measurement unit, the measurement electrode being either of the working electrode (101) or the counter electrode (103). The second analogue input (ADC-1) is operatively coupled with the reference electrode (102). The microcontroller (1200) is configured to control, by providing a control voltage to the control output (DAC), a potential difference between the working electrode (101) and the counter electrode (103) to equal a predefined polarization voltage.



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SYSTEM, METHOD AND ARTICLE FOR CONTROLLING THE DISPENSING OF INSULIN

NºPublicación: US2017258997A1 14/09/2017

Solicitante:
DOSE SAFETY [US]

Resumen de: US2017258997A1

An integrated circuit includes circuitry to control a process. The process includes adjusting fuzzy-logic control parameters based on received and retrieved blood glucose-related data, predicting blood glucose levels based on the received blood-glucose-related data, and generating control signals to control dispensing of insulin based on the received blood glucose-related data and the fuzzy-logic control parameters. The process may include predicting blood glucose levels based on the retrieved blood glucose-related data. The process may include transitioning between a post-meal correction protocol and a fasting protocol. The process may include transitioning from a post-meal correction protocol to a fasting protocol when a fasting criteria is satisfied.



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Optimizing Analyte Sensor Calibration

NºPublicación: US2017258379A1 14/09/2017

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2017258379A1

Method and apparatus for optimizing analyte sensor calibration including receiving a current blood glucose measurement, retrieving a time information for an upcoming scheduled calibration event for calibrating an analyte sensor, determining temporal proximity between the current blood glucose measurement and the retrieved time information for the upcoming calibration event, initiating a calibration routine to calibrate the analyte sensor when the determined temporal proximity is within a predetermined time period, and overriding the upcoming scheduled calibration event using the current blood glucose measurement are provided.



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Pharmaceutical Compositions Comprising Canagliflozin

NºPublicación: US2017258761A1 14/09/2017

Solicitante:
SANDOZ AG [CH]

Resumen de: US2017258761A1

The present invention belongs to the field of pharmaceutical industry and relates to a dry pharmaceutical composition comprising Canagliflozin, as well as to a process for preparing the same. Such dry pharmaceutical composition is useful as a medicament, especially for the normalization of plasma glucose levels.



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ANALYTE MEASURING PATCH

NºPublicación: EP3216395A1 13/09/2017

Solicitante:
ROCHE DIABETES CARE GMBH [DE]
F HOFFMANN-LA ROCHE AG [CH]

Resumen de: EP3216395A1

Disclosed is an analyte measuring patch for invasive measuring a concentration of an analyte, in particular glucose. The analyte measuring patch includes a sensor with a working electrode (101), a counter electrode (103) and a reference electrode (102). The patch further includes an electronics unit with a microcontroller (1200) and a current measurement unit. The microcontroller (1200) includes a control output (DAC), a first analogue input (ADC-1) and a second analogue input (ADC-2). The control output (DAC) is operatively coupled with a control electrode, the control electrode being either of the working electrode or (101) or the counter electrode (103). The first analogue input (ADC-2) is operatively coupled with a measurement electrode via the current measurement unit, the measurement electrode being either of the working electrode (101) or the counter electrode (103). The second analogue input (ADC-1) is operatively coupled with the reference electrode (102). The microcontroller (1200) is configured to control, by providing a control voltage to the control output (DAC), a potential difference between the working electrode (101) and the counter electrode (103) to equal a predefined polarization voltage.



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ANALYTE MONITORING SYSTEM

NºPublicación: EP3216390A1 13/09/2017

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: EP3216390A1

An analyte monitoring system comprising a transcutaneous glucose sensor and a data processing unit capable of bidirectional communication using an encrypted communication key based on identification information of the data processing unit.



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Multi-location top loading insulin infusion set

NºPublicación: US9757515B1 12/09/2017

Solicitante:
FLEXTRONICS AP LLC [US]

Resumen de: US9757515B1

A manual infusion set comprises a top connector lockable in a plurality of positions. The top connector and tubing is initially loaded from the top and then slid forward in order to puncture the septum. Once the connector is attached, it cannot be rotated. With the connector locked in place, flexible tubing connects the septum hub with a medicine pump, which continually supplies medicine such as insulin to a user.



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PATIENT DIABETES MONITORING SYSTEM WITH CLUSTERING OF UNSUPERVISED DAILY CGM PROFILES (OR INSULIN PROFILES) AND METHOD THEREOF

NºPublicación: WO2017151369A1 08/09/2017

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: WO2017151369A1

A patient diabetes monitoring system with an efficient unsupervised daily monitoring profile clustering algorithm, a method, and a computer product thereof are disclosed. The system may include a physiological data input device or sensor which receives a plurality of physiological measurements to generate a dataset, a memory which stores a clustering algorithm, and a processor. The clustering algorithm when executed by the processor, causes the processor to automatically pre-process the dataset to control an amount of bias/aggressiveness from the collected unsupervised daily monitoring profiles, thereby generating a pre-processed dataset, build a similarity matrix from the pre-processed dataset, and output an optimum number of similarity clusters found by the processor from the similarity matrix.



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BOLUS CALCULATOR WITH PROBABILISTIC GLUCOSE MEASUREMENTS

NºPublicación: WO2017151372A1 08/09/2017

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: WO2017151372A1

Methods and devices involving using a bolus calculator for calculating a correction insulin dose accounting for continuous glucose monitoring noise. More specifically, methods and devices using an algorithm executed by a processor of the bolus calculator and using a glucose measurement and uncertainty of the glucose measurement to determine if a standard correction dose should be adjusted once calculations are performed for the standard correction dose and hypoglycemia-averse correction insulin dose and the two doses are compared.



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PROBABILITY BASED CONTROLLER GAIN

NºPublicación: WO2017151370A1 08/09/2017

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: WO2017151370A1

Methods and systems are disclosed for estimating a glucose level of a person having diabetes and selecting automatically open-loop and closed-loop control for a connected therapy delivery device. The method may comprise analyzing measured glucose results and corresponding impedance values received from a glucose sensor coupled to the person with a probability analysis tool implemented by a microcontroller to determine a total quality score that is based on the minimum constraint of a probability of glucose sensor accuracy determined measured glucose results and a probability of sensing quality determined from the impedance values. The microcontroller may estimate the glucose level of the person with a recursive filter based on the plurality of measured glucose results weighted with the total quality score and select automatically either open-loop control or closed-loop control for the connected therapy delivery device based on the value of the total quality score.



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METHOD AND SYSTEM FOR ANALYZING GLUCOSE MONITORING DATA INDICATIVE OF A GLUCOSE LEVEL AND A NON-TRANSITORY COMPUTER READABLE MEDIUM

NºPublicación: US2017251982A1 07/09/2017

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: US2017251982A1

A computer-implemented method and a system for analyzing glucose monitoring data indicative of a glucose level, comprising: presenting by a data processing device provided a graphical window on a display device wherein the graphical window comprises a time abscissa axis that defines time units, and a glucose ordinate axis that defines glucose units; receiving a plurality of glucose monitoring values associated with a monitoring time period by the data processing device; segmenting the plurality of glucose monitoring values into a plurality of glucose monitoring traces indicative of the glucose level; defining a reference trace segment; determining the reference trace segment for each of the plurality of glucose monitoring traces; and plotting, for a time window comprising the reference trace segment, the plurality of glucose monitoring traces within the graphical window. Furthermore, a non-transitory computer readable medium is disclosed.



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PATIENT DIABETES MONITORING SYSTEM WITH CLUSTERING OF UNSUPERVISED DAILY CGM PROFILES (OR INSULIN PROFILES) AND METHOD THEREOF

Nº publicación: US2017251980A1 07/09/2017

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: US2017251980A1

A patient diabetes monitoring system with an efficient unsupervised daily monitoring profile clustering algorithm, a method, and a computer product thereof are disclosed. The system may include a physiological data input device or sensor which receives a plurality of physiological measurements to generate a dataset, a memory which stores a clustering algorithm, and a processor. The clustering algorithm when executed by the processor, causes the processor to automatically pre-process the dataset to control an amount of bias/aggressiveness from the collected unsupervised daily monitoring profiles, thereby generating a pre-processed dataset, build a similarity matrix from the pre-processed dataset, and output an optimum number of similarity clusters found by the processor from the similarity matrix.


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