TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 95 resultados LastUpdate Última actualización 24/09/2018 [16:30:00] pdf PDF




Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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Apparatus for measuring blood sugar level

NºPublicación: KR20180097370A 31/08/2018

Solicitante:
SAMSUNG ELECTRONICS CO LTD [KR]

Resumen de: KR20180097370A

본 발명은 혈당 측정 장치에 관한 것으로서, 상기 혈당 측정 장치는, 피부부착면을 갖는 패치 형태의 몸체부; 피부 속으로 침투 가능한 바늘 형태를 가지며, 상기 몸체부 피부부착면에 마련되고, 혈당측정전극 및 제1임피던스전극을 포함하는 피부침투부; 상기 피부침투부로부터 이격되어 상기피부침투부를 둘러싸는 형태로 마련되는 적어도 하나의 제2임피던스전극; 상기 혈당측정전극, 상기 제1임피던스전극 및 상기 제2임피던스전극에 전원을 공급하는 전원공급부; 및 상기 혈당측정전극을 통해 피부 속 혈당값을 측정하고, 상기 제1임피던스전극과 제2임피던스전극을 통해 피부의 상태에 대응하는 임피던스값을 측정하는 처리부를 포함한다. 이에 의하여, 보다 깊고 넓은 영역에 걸쳐 피부 트러블 발생 여부를 조기에 탐지할 수 있다.



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SOFTWARE APPLICATIONS RESIDING ON HANDHELD ANALYTE DETERMINING DEVICES

NºPublicación: US2018242891A1 30/08/2018

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2018242891A1

Presented herein is a handheld analyte measurement device. The analyte measurement device includes one or more software applications to help the user manager their diabetes. Embodiments and descriptions of the various applications are provided below in conjunction with the handheld analyte measurement device.



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ANALYTE SENSOR

NºPublicación: US2018242894A1 30/08/2018

Solicitante:
DEXCOM INC [US]

Resumen de: US2018242894A1

Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.



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RAPID ACTION INSULIN FORMULATIONS AND PHARMACEUTICAL DELIVERY SYSTEMS

NºPublicación: US2018243380A1 30/08/2018

Solicitante:
THERMALIN DIABETES INC [US]

Resumen de: US2018243380A1

The present invention provides rapid-acting insulin and insulin analogue formulations. The invention further provides delivery devices, particularly infusion sets, which allow for the rapid absorption of insulin and insulin analogues, as well as other active agents. Methods of using the insulin and insulin analogue formulations as well as the insulin delivery devices for treating subjects with diabetes mellitus are also provided.



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SYSTEM FOR USE IN CHILD PHYSIOLOGICAL PARAMETERS COLLECTION AND EMOTION DETECTION

NºPublicación: WO2018152757A1 30/08/2018

Solicitante:
YANG XIAOMING [CN]

Resumen de: WO2018152757A1

A system for use in child physiological parameters collection and emotion detection, comprising: a data collection module, a signal processing module and a data receiving and sending module; the data collection module comprises a biometric sensor, a skin conduction value sensor, an electrocardio signal detection sensor, a filter amplification module, an A/D conversion module, a power supply module, a skin temperature measurement module, a skin resistance measurement module, a pulse measurement module, a display module, a collection control module, a spectral sensor which may measure blood oxygen, pressure and glucose levels, a skin electro-response sensor for use in measuring sweat levels and pH value, and an ultraviolet ray index sensor; the biometric sensor comprises an accelerometer, a gyroscope, a magnetometer, and a pressure sensor therein; the skin temperature measurement module, the skin resistance measurement module, the pulse measurement module and the display module are connected to the collection control module, respectively, while the data receiving and sending module is connected to the data collection module and the signal processing module.



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APPARATUS AND METHOD FOR OPTICAL SPECTROSCOPY AND BIOIMPEDANCE SPECTROSCOPY USING A MOBILE DEVICE CASE TO GATHER PHYSIOLOGICAL INFORMATION

NºPublicación: WO2018156624A1 30/08/2018

Solicitante:
VITA ANALYTICS INC [US]

Resumen de: WO2018156624A1

A mobile touchable system for user fitness and health monitoring is presented. The system is designed in one form as a mobile phone case and in another form as integrated in a mobile phone. It encompasses a series of measurement devices, including, but not limited to, arrays of electrodes for bio-impedance analysis, impedance tomography, and electrocardiographs, near-infrared spectroscopy for glucose level measurement, and heart rate monitoring. The touchable system performs incidental measurement in the background each time the user holds the mobile phone and hence enables long term health monitoring without user intervention. The touchable monitoring system further performs targeted spot measurements by following defined procedures. Spot measurement is enhanced through an extension measurement cable. Furthermore, an extension strap along with the mobile touchable system provides detailed activity tracking. The touchable system performs long term health monitoring, and provides early alerts for abnormal condition such as diabetes, dehydration, hypertension, cardiovascular anomalies, breast cancer and prostate cancer.



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Methods and apparatuses for providing adverse condition notification in analyte monitoring systems

NºPublicación: AU2018214124A1 30/08/2018

Solicitante:
ABBOTT DIABETES CARE INC

Resumen de: AU2018214124A1

A method for concurrently supporting multiple data communication modes including data communication in response to a request and autonomous data communication based on monitored parameter detection is disclosed. The method comprises receiving time spaced glucose signals from an in vivo glucose sensor in fluid contact with interstitial fluid; storing the received time spaced glucose signals in a memory; detecting a request for real time glu cose level information and, in response thereto, transmitting by a first data communication module, the stored glucose signals and real time glucose signal received from the glucose sensor to a remotely located device; processing a subset of the received time spaced glucose signals to identify a predetermined number of consecutive glucose data points from the subset of the received time spaced glucose signals indicating an impending adverse condition; gen erating a notification signal when the impending adverse condition is identified; and activat ing a second data communication module to wirelessly transmit the generated notification signal to the remotely located device only when the notification signal is generated, wherein the first and the second data communication modules are hardware components of sensor electronics coupled to the in vivo glucose sensor, and wherein the second data communica tion module is adapted to transmit autonomously relative to the first data communication module. -25-



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METHOD FOR TREATING, STABILIZING OR SLOWING DOWN BRAIN GLUCOSE METABOLISM DEFICIT

NºPublicación: SG10201806010RA 30/08/2018

Solicitante:
N V NUTRICIA [NL]

Resumen de: SG10201806010RA

METHOD FOR TREATING, STABILIZING OR SLOWING DOWN BRAIN GLUCOSE METABOLISM DEFICIT The invention pertains to the use of (i) one or more of uridine and cytidine, or salts, 5 phosphates, acyl derivatives or esters thereof, and (ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof in the manufacture of a composition for use in a method for treating, stabilizing or slowing down brain glucose metabolism deficit in a subject in need thereof. 10 [No suitable figure]



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METHODS, DEVICES, AND SYSTEMS FOR PHYSIOLOGICAL PARAMETER ANALYSIS

NºPublicación: WO2018156584A1 30/08/2018

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: WO2018156584A1

Methods, devices, and systems may use a kinetic model to determine physiological parameters related to the kinetics of red blood cell glycation, elimination, and generation. Such physiological parameters can be used, for example, to determine a more reliable calculated HbA1c. In another example, a method may comprise: receiving a plurality of glucose levels over a time period; receiving a glycated hemoglobin (HbA1c) level corresponding to an end of the time period; determining at least one physiological parameter selected from the group consisting of: a red blood cell glycation rate constant (kgly), a red blood cell generation rate constant (kgen), a red blood cell elimination constant (kage), and an apparent glycation constant (K), based on (1) the plurality of glucose levels and (2) the HbA1c level; and adjusting a glucose level target based on the at least one physiological parameter.



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LOW OXYGEN IN VIVO ANALYTE SENSOR

NºPublicación: EP3366201A1 29/08/2018

Solicitante:
DEXCOM INC [US]

Resumen de: EP3366201A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.



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SYSTEM AND METHOD FOR BODY MASS INDEX RELATION TO PATIENT DIFFERING PSYCHOLOGICAL STRESS EFFECT ON BLOOD GLUCOSE DYNAMICS IN PATIENTS WITH INSULIN DEPENDENT DIABETES

NºPublicación: WO2018152349A1 23/08/2018

Solicitante:
UNIV OF VIRGINIA PATENT FOUNDATION D/B/A UNIV OF VIRGINIA LICENSING AND VENTURES GROUP [US]

Resumen de: WO2018152349A1

An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.



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SEROLOGIC ASSAY FOR SILENT BRAIN ISCHEMIA

NºPublicación: WO2018152537A1 23/08/2018

Solicitante:
UNIV CALIFORNIA [US]

Resumen de: WO2018152537A1

A method for detection or monitoring status of silent brain ischemia (SBI) and cerebrovascular health. The assay reagents and methods described herein provide a specific indicator of cerebral microvascular disease, enabling clinicians to identify patients at risk for the development of SBI. A method of treating a subject having silent brain ischemia and/or metabolic syndrome comprises administering to the subject aspirin therapy, blood pressure therapy, body weight management, and/or a program of diet and exercise when levels of two or more SBI markers are elevated. Described herein are molecules that are produced by cerebral endothelial cells exposed to chronic vascular risk factors including obesity, hyperlipidemia, hypertension, and glucose intolerance. These stress molecules produced by cerebral endothelial cells are detectable in the serum and serve as diagnostic indicators of brain-specific endothelial cell damage and correlate with MRI indicators of silent stroke and impaired cognitive function.



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Blood glucose sensor insertion device

NºPublicación: KR101891309B1 23/08/2018

Solicitante:
T4L INC [KR]

Resumen de: KR101891309B1

본 발명은 인체 부착식 혈당측정센서 삽입장치에 관한 것으로서, 피하 침투를 위한 바늘이 일체로 형성된 센서모듈 전체를 사용자의 신체에 부착시키는 삽입장치를 고안함으로써 사용자가 번거로운 작업공정이 없이 신속하고 편리하게 혈당측정센서를 신체에 부착할 수 있도록 한 것이다.



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SYSTEM, METHOD, AND COMPUTER READABLE MEDIUM FOR A BASAL RATE PROFILE ADAPTATION ALGORITHM FOR CLOSED-LOOP ARTIFICIAL PANCREAS SYSTEMS

NºPublicación: WO2018152358A1 23/08/2018

Solicitante:
UNIV OF VIRGINIA PATENT FOUNDATION D/B/A UNIV OF VIRGINIA LICENSING AND VENTURES GROUP [US]

Resumen de: WO2018152358A1

An insulin device configured to control an insulin dosage by adapting a basal rate profile. The insulin device includes a sensor configured to produce a blood glucose level measurement data, and detect changes of the blood glucose level measurement data over time; a processor and associated computer memory device configured to receive the blood glucose level measurement data and a basal rate profile, such that the basal rate profile includes a basal rate set point that corresponds to an insulin delivery reference for a nominal blood glucose, and the basal rate profile is stored in the computer memory device. The insulin device also includes an insulin dispensing valve controlled by the processor to administer insulin in accordance with the received basal rate profile, such that the processor is configured to update the basal rate set point over a time period based on both an assessment of at least one of a risk of hyperglycemia and a risk of hypoglycemia from historical blood glucose data, and patterns of actions taken by the insulin device to mitigate glycemic risk during the time period. The insulin dispensing valve is controlled by the processor to administer insulin in accordance with the updated basal rate set point.



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Visualization and analysis tool for a drug delivery system

NºPublicación: AU2017216336A1 23/08/2018

Solicitante:
ANIMAS CORP

Resumen de: AU2017216336A1

A visualization and analysis tool is provided for an insulin delivery system, such as an artificial pancreas, in which insulin is delivered based upon a system algorithm using a pump that is patient controllable in order to adjust insulin delivery relative to a baseline delivery rate;



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METHODS, DEVICES, AND SYSTEMS FOR PHYSIOLOGICAL PARAMETER ANALYSIS

NºPublicación: US2018235524A1 23/08/2018

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2018235524A1

Methods, devices, and systems may use a kinetic model to determine physiological parameters related to the kinetics of red blood cell glycation, elimination, and generation. Such physiological parameters can be used, for example, to determine a more reliable calculated HbA1c. In another example, a method may comprise: receiving a plurality of glucose levels over a time period; receiving a glycated hemoglobin (HbA1c) level corresponding to an end of the time period; determining at least one physiological parameter selected from the group consisting of: a red blood cell glycation rate constant (kgly), a red blood cell generation rate constant (kgen), a red blood cell elimination constant (kage), and an apparent glycation constant (K), based on (1) the plurality of glucose levels and (2) the HbA1c level; and adjusting a glucose level target based on the at least one physiological parameter.



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SYSTEM AND METHOD FOR DETECTING A HEALTH CONDITION USING AN OPTICAL SENSOR

NºPublicación: US2018235532A1 23/08/2018

Solicitante:
SANMINA CORP [US]

Resumen de: US2018235532A1

A biosensor includes an optical sensor circuit that emits light directed at skin tissue of a patient at a plurality of wavelengths. A first and second spectral response of light reflected from the tissue is obtained around a first wavelength in a UV range and a second wavelength in an IR range. A measurement of a substance in blood flow is then determined from the spectral responses. A risk of a health condition is obtained using the measurement. The health condition may include one or more of hyperglycemia, diabetes or hypoglycemia.



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ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

NºPublicación: EP3363444A1 22/08/2018

Solicitante:
VIACYTE INC [US]

Resumen de: EP3363444A1

The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.



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METHOD FOR PREDICTING THE RISK OF DEVELOPING PARATROPHY IN CHILDREN BORN BY WOMEN WITH TYPE 1 DIABETES MELLITUS IN THE INFANCY

NºPublicación: RU2664634C1 21/08/2018

Solicitante:
FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE URALSKIJ NAUCHNO ISSLEDOVATELSKIJ INSTITUT OKHRA [RU]

Resumen de: RU2664634C1

FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to pediatrics, neonatology, and can be used to predict the risk of paratrophy in children born to women with type 1 diabetes by the first year of life. To do this, establish the duration of diabetes and the presence or absence of hypothyroidism in the mother. In a child at the age of 3 months, determine the body weight in grams and the blood sugar level and calculate the prognostic index D by the formula: D=-0.143x-2.338x-0.002x-0.461x+16.247, where x- duration of diabetes mellitus in women (years), x- presence or absence of hypothyroidism in the mother 1 or 0, respectively, x- body weight of the child at the age of 3 months (g), x- sugar level in the blood of the child at the age of 3 months (mmol/l), Constant - 16.247. For D>0, a favorable prediction is judged, and for D≤0 predict a high risk of paratrophy by the year of life.EFFECT: method provides an opportunity to carry out prevention of this condition by isolating a risk group for the development of paratrophy at the outpatient stage.1 cl, 2 ex



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Blood Glucose Test Strip

NºPublicación: KR20180092563A 20/08/2018

Solicitante:
KIM KYEONG WON [KR]

Resumen de: KR20180092563A

본 발명은 혈당 테스트 스트립에 관한 것으로서, 특히 대면형 전극구조를 갖는 전기화학식 자가측정용 혈당 테스트 스트립에서 종래 보조전극용 패드를 하부기판 상에 �xD615;성하기 위하여 상부기판 하부의 전도층을 하부기판 상의 전도층으로 연결하는 공정이 제거되어 품질이 우수하면서도 저가인 혈당 테스트 스트립에 관한 것이다. 이를 위하여, 본 발명은 하부기판, 중간기판, 상부기판이 순차적으로 적층되고 중간기판의 일부영역을 제거하여 시료실이 형성되는 대면형 전극구조의 전기화학식 혈당 테스트 스트립에 있어서, 상기 상부기판과 중간기판의 일부영역을 제거하여 하부기판 상부의 전도층을 노출해서 형성한 작동전극용 패드; 및 상기 하부기판과 중간기판의 일부영역을 제거하여 상부기판 하부의 전도층을 노출해서 형성한 보조전극용 패드; 를 포함하여 구성되는 것을 특징으로 하는 혈당 테스트 스트립을 제공한다.



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Implantable sensor apparatus and methods

NºPublicación: AU2016382976A1 16/08/2018

Solicitante:
GLYSENS INCORPORATED

Resumen de: AU2016382976A1

Implantable sensor apparatus and methods of implantation. In one embodiment, a fully implantable, biocompatible sensor is disposed within a cavity or pocket formed within a living being, such that the sensor remains in a desired orientation and placement so as to enhance the performance of the sensor, and mitigate the effects of one or more factors potentially deleterious to the operation of the sensor and the host being. In one implementation, the sensor comprises an implantable biocompatible oxygen-based glucose sensor which is implanted deep within the being's torso tissue proximate the extant fascia, and oriented such that an active detector aspect of the device faces away from the being's skin surface. In one variant, the deep placement, orientation, and construction of the sensor itself cooperate to enhance the performance of the sensor, especially over extended periods of time, with little need for external calibration.



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INSULIN ADMINISTRATION SYSTEM USING CONTINUOUS BLOOD GLUCOSE DETECTION

NºPublicación: WO2018147483A1 16/08/2018

Solicitante:
CHOI KYU DONG [KR]

Resumen de: WO2018147483A1

The present invention relates to an insulin administration system using continuous blood glucose detection, comprising: a continuous blood glucose measuring sensor unit for continuously measuring the measured value of the blood glucose of a person being measured; a blood glucose analysis/comparison module for receiving the measured value of the blood glucose from the continuous blood glucose measuring sensor unit and calculating, in real time, a dose of insulin to be administered to the person being measured, in according with the patient response characteristic of the person being measured; and a data transmission/reception module for forwarding the dose of insulin, which has been calculated by the blood glucose analysis/comparison module, to an insulin administration apparatus, so that just as much insulin as the dose of insulin can be administered in real time, wherein, if the measured value of the blood glucose is a function determined by the patient response characteristic based on the dose of insulin, the blood glucose analysis/comparison module determines the dose of insulin by using the inverse function of the patient response characteristic so that the measured value of the blood glucose comes within a predetermined blood glucose level target range.



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ASSEMBLY TO ADMINISTER INSULIN FROM A CARTRIDGE

NºPublicación: US2018228979A1 16/08/2018

Solicitante:
EMPERRA GMBH E HEALTH TECH [DE]

Resumen de: US2018228979A1

An assembly for the administration of a selected dosage of insulin or other medicaments from a cartridge by moving a plug guided in said cartridge, comprises an adapter assembly for adapting cartridges with different dimensions or contents. The adapter assembly comprises a first threaded element threaded with a thread lead and movable in a moving direction to move the plug, and a second threaded element threaded with a thread lead for setting a selected dosage, pivotably screwed to said first threaded element and limiting the movement of said first threaded element, and wherein said thread lead of said first element and said thread lead of said second threaded element are adapted to the dimensions and/or the contents of said cartridge.



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PORTABLE APPARATUS FOR NONINVASIVELY MEASURING BLOOD GLUCOSE LEVEL AND OPERATING METHOD THEREOF

NºPublicación: US2018228433A1 16/08/2018

Solicitante:
KIM HOON [SG]

Resumen de: US2018228433A1

Disclosed is an operating method of a portable apparatus for noninvasively measuring blood glucose levels, and the method comprising (a) measuring a first signal value according to ambient environmental light and temperature by using at least one light receiving elements when an LED which emits light with wavelengths to be absorbed into or scattered by glucose is switched off; (b) measuring a second signal value according to incident light which is scattered by or transmitted through subject tissue and enters the photodetecting unit when the LED is switched on; (c) calculating a glucose concentration measurement of a subject by using the first signal value and the second signal value; and (d) wherein the quantity of light detected by the photodetecting unit is adjusted by feeding the difference between the glucose concentration measurement and a first reference value back to the photodetecting unit.



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PORTABLE APPARATUS FOR NONINVASIVELY MEASURING BLOOD GLUCOSE LEVEL AND OPERATING METHOD THEREOF

Nº publicación: US2018228413A1 16/08/2018

Solicitante:
KIM HOON [SG]

Resumen de: US2018228413A1

Provided is a method for measuring blood glucose levels of a subject with a portable apparatus for noninvasively measuring blood glucose levels including at least one light receiving element for detecting light by using different light integration times, including: (a) switching on an LED for emitting light having wavelength absorbed in or scattered by glucose; (b) measuring a first signal value according to light which is reflected off the surface skin layer of the subject and enters in response to a first light integration time in the situation where the light is radiated; (c) adjusting a second light integration time for measuring light reflected off the inner skin layer of the subject based on the first signal value; (d) measuring a second signal value according to the light which is reflected off the inner skin layer of the subject and enters in response to the adjusted second light integration time; and (e) producing the blood glucose level of the subject by using a third signal value according to light which enters due to an ambient environment and the second signal value in the situation where the LED is switched off.


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