TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 116 resultados LastUpdate Última actualización 23/03/2019 [16:45:00] pdf PDF

Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days

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NEUROMODULATION FOR METABOLIC CONDITIONS OR SYNDROMES

NºPublicación: US2019069942A1 07/03/2019

Solicitante:

METAVENTION INC [US]

US_2019059969_A1

Resumen de: US2019069942A1

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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Method and System for Providing Basal Profile Modification in Analyte Monitoring and Management Systems

NºPublicación: US2019070360A1 07/03/2019

Solicitante:

ABBOTT DIABETES CARE INC [US]

US_2018289892_A1

Resumen de: US2019070360A1

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.

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METHOD AND APPARATUS FOR NON-INVASIVE GLUCOSE MEASUREMENT

NºPublicación: US2019069821A1 07/03/2019

Solicitante:

CNOGA MEDICAL LTD [IL]

Resumen de: US2019069821A1

An apparatus for monitoring blood glucose comprising an invasive component for invasively measuring blood glucose and a non-invasive component, including color image sensor(s) to generate images from absorption of light that traversed the tissue, to receive a body part and generate a non-invasive blood glucose reading. Processor(s) convert the images into a vector V associated with a particular at least one invasive blood glucose measurement gk1, form a regular learning matrix, λ, implement a noninvasive isolation mechanism of the tissue glucose level by unique association of the vector Vk with an invasive blood glucose level, determine a neural network from the learning set λ by pairing vectors into a branch and forming multiple branches into loops, wherein two vectors are paired if they have a pre-defined similarity in the blood glucose levels that each are associated with; and calibrate the neural network by having it pass at least one test.

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INSERTION GUIDE NEEDLE INTEGRATED WITH BLOOD GLUCOSE MEASUREMENT SENSOR OF CARBON NANOTUBE STRUCTURE

NºPublicación: WO2019045503A1 07/03/2019

Solicitante:

CHOI KYU DONG [KR]

Resumen de: WO2019045503A1

The present invention relates to an insertion guide needle integrated with a blood glucose measurement sensor of a carbon nanotube structure. More particularly, the present invention relates to an insertion guide needle (100) integrated with a blood glucose measurement sensor of a carbon nanotube structure, comprising: a carbon nanotube blood glucose measurement sensor (110) composed of a carbon nanotube; a carbon nanotube insertion guide needle (120) having a sharp infiltration tip (121) formed at the end of an infiltration direction and having a sensor seating part (122) which is open on one side and on which the carbon nanotube blood glucose measurement sensor (110) can be seated; and a sensor-attached carbon fiber filament (130) connected to the carbon nanotube insertion guide needle (120) at an end of the infiltration direction and connected to the carbon nanotube blood glucose measurement sensor (110) at an opposite end of the infiltration direction.

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METHODS, DEVICES AND SYSTEMS FOR ESTIMATING NUTRITIONAL ELEMENT CONTENT IN FOODS

NºPublicación: WO2019046530A1 07/03/2019

Solicitante:

ROCHE DIABETES CARE INC [US]
ROCHE DIABETES CARE GMBH [DE]
HOFFMANN LA ROCHE [CH]

Resumen de: WO2019046530A1

Systems and methods are provided for improving nutritional element content estimates from one or more individuals and/or determining a therapy or treatment based on a nutritional element content estimate and improving diabetes management. The systems and methods include a therapy or treatment display based on at least one nutritional element content estimate and at least one proficiency index respectively assigned to an individual to improve accuracy and reliability when estimating nutritional element content in foods and/or therapy or treatment based therefrom.

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SYSTEMS, METHODS, APPARATUSES AND DEVICES FOR DRUG OR SUBSTANCE DELIVERY

NºPublicación: WO2019043702A1 07/03/2019

Solicitante:

TRIPLE JUMP ISRAEL LTD [IL]
BEN DAVID YISHAI [IL]
SALOMON KFIR [IL]
YODFAT OFER [IL]
SHINAR GUY [IL]

Resumen de: WO2019043702A1

Embodiments of the present disclosure are directed to miniature insulin patch pump, assistance devices (e.g., for reservoir filling and /or cannula insertion), and methods related thereto. For example, in some embodiments, a substance/drug-delivery patch pump is provided and includes a reusable part (RP) including a power source, a driving mechanism, and an electronic module, and a disposable part (DP), where the disposable part can include at least a plurality of an adhesive base, a reservoir, a dosing mechanism, and a cannula.

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GLUCOSE SENSOR AND METHOD FOR MANUFACTURING SAME

NºPublicación: WO2019045232A1 07/03/2019

Solicitante:

DONGWOO FINE CHEM CO LTD [KR]

Resumen de: WO2019045232A1

The present invention relates to a method for manufacturing a glucose sensor. The present invention comprises: an electrode forming step of forming an electrode part composed of a plurality of electrodes on a substrate; an electrode protection/electron transport function layer forming step of forming an electrode protection/electron transport function layer including an electrode protector and an electron transporter on the electrode part; a glucose reaction part forming step of forming a glucose reaction part on the electrode protection/electron transport function layer; and an ion exchange membrane forming step of forming an ion exchange membrane on the glucose reaction part. According to the present invention, the number, time, and cost of the processes required to manufacture a glucose sensor can be reduced.

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SYSTEM AND METHOD FOR DETECTING APPLIED FORCE DURING INJECTION

NºPublicación: WO2019046436A1 07/03/2019

Solicitante:

BECTON DICKINSON CO [US]

Resumen de: WO2019046436A1

A medical device (100) includes an insulin pen (102), a pen needle (104) and a force sensor (106). The device also includes a microprocessor (206) to receive a signal from the force sensor (106). Audible and/or visual indicators (218, 220) provide feedback to a user to encourage proper injection technique. The device may also include an adaptor assembly comprising a sensor housing (306) and a first sensor (304) within the sensor housing, and a transfer needle assembly (308), the transfer needle assembly providing a connection (310) for a pen needle, and providing a fluid conduit between the pen needle (312) and the insulin pen (302). A second force sensor (314) is associated with a thumb button of the insulin pen (302).

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METHODS AND DEVICE ARRANGEMENT FOR PHYSICAL ACTIVITY THRESHOLDS REDUCING RISKS OF DIABETES, CARDIOVASCULAR DISEASES, INFLAMMATIONS, DEMENTIA, CANCERS AND MORTALITY IN SEDENTARY SUBJECTS

NºPublicación: WO2019043292A1 07/03/2019

Solicitante:

GLEAP HEALTH TECH OY [FI]

Resumen de: WO2019043292A1

High blood levels of very low density lipoprotein lipids (VLDLs) and glycoprotein acyl (Glyc A) are known to increase risk of diabetes, cardiovascular diseases, inflammations, cognitive impairments, cancers and premature deaths in sedentary persons. The invention determines physical activity thresholds of daily steps and accelerations to reduce plasma concentrations of VLDLs and Glyc A. The method and device is an accelerometer recording and classifying numbers of steps and accelerations and comparing the person's steps and accelerations with those shown to reduce VLDLs and Gly A. The invention is characterized in that if the daily number of accleration maxima exceeds the given threshold of 2980 steps in the acceleration range 1.3 - 1.7 g, the person has performed physical activity, typically known to reduce circulating VLDLs and Glyc A.

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Reconstitution device for IV fluids and method of use

NºPublicación: AU2017299427A1 07/03/2019

Solicitante:

CAREFUSION 303 INC

CA_3031061_A1

Resumen de: AU2017299427A1

A system is provided for storage and reconstitution of IV solutions. The system may include one or more storage and reconstitution devices each configured to store and manipulate IV solution containers containing IV solutions in crystalline form that include hydration chemicals and therapeutic drugs. Crystalline hydration chemicals may include crystalline salts and sugars. The containers may be dimensionally precise enough for mechanical manipulation and configured such that sharp objects such as needles are not needed for fluid delivery to or from the container. Each storage and reconstitution device may store stacked containers and may include components for retrieval of a container from the storage and for reconstitution of the contents therein using a sterile water source within the device. IV doses may be manufactured, under appropriate standards, that can be mechanically reconstituted to produce high-quality doses in real time on the patient care unit or in the pharmacy.

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IN-SITU CHEMISTRY STACK FOR CONTINUOUS GLUCOSE SENSORS

NºPublicación: EP3449006A1 06/03/2019

Solicitante:

MEDTRONIC MINIMED INC [US]

CN_109312383_A

Resumen de: WO2017189764A1

Embodiments of the invention provide an in-situ polymerization technique for creating a glucose sensor chemistry stack. An analyte sensor comprises a crosslinked polymer matrix in contact with an electrode. The crosslinked polymer matrix is formed by exposing ultraviolet (UV) light to a polymer matrix mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, and an oxidoreductase. The oxidoreductase is covalently linked to the crosslinked polymer matrix. In typical embodiments, the oxidoreductase is a glucose oxidase-acrylate bioconjugate. In one or more embodiments, the analyte sensor apparatus further comprises a glucose limiting membrane positioned over the crosslinked polymer matrix. The glucose limiting membrane is formed by exposing ultraviolet (UV) light to a glucose limiting membrane mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, ethylene glycol, and water.

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REAL-TIME DENOISING AND PREDICTION FOR A CONTINUOUS GLUCOSE MONITORING SYSTEM

NºPublicación: EP3448247A1 06/03/2019

Solicitante:

SENSEONICS INCORPORATED [US]

WO_2017190143_A1

Resumen de: US2017311897A1

An analyte monitoring system may include an analyte sensor and a transmitter. The analyte sensor may include an indicator element that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator element. The analyte sensor may be configured to generate one or more raw signals indicative of one or more analyte amounts or concentrations. The transmitter may be configured to receive from the analyte sensor one or more raw signals indicative of analyte concentration. The transmitter may be configured to denoise the raw signal using a real-time filtering technique with one or more time-varying parameters. The transmitter may be configured to predict ahead of time an analyte concentration based on one or more of the received one or more raw signals using one or more prediction models.

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INSULIN DELIVERY SYSTEM AND METHODS WITH RISK BASED SET POINTS

NºPublicación: EP3448248A1 06/03/2019

Solicitante:

BIGFOOT BIOMEDICAL INC [US]

CN_108633250_A

Resumen de: US2017332952A1

A method may include obtaining blood glucose level readings over a diurnal period for each of a plurality of days and determining an estimated variability of the blood glucose levels over the diurnal period for the plurality of days. The method may also include modifying, based on the estimated variability of the blood glucose level, a target blood glucose level to a modified target blood glucose level, and delivering insulin, using an insulin pump, during the diurnal period based on the modified target blood glucose level.

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METHOD OF DIAGNOSTICS OF VARIANTS OF ACUTE ISCHEMIC DAMAGE TO THE PANCREAS IN CASE OF ACUTE CARDIOVASCULAR INEFFICIENCY WITH IMPAIRED MICROCIRCULATORY BLOOD FLOW AND CENTRALIZATION OF BLOOD CIRCULATION OF VARIOUS ETHIO-PATHOGENETIC NATURE

NºPublicación: RU2681264C1 05/03/2019

Solicitante:

DEGTYAREV OLEG LEONIDOVICH [RU]

Resumen de: RU2681264C1

FIELD: medicine.SUBSTANCE: invention relates to medicine and can be used to diagnose acute ischemic damage to the pancreas. Blood amylase and glucose levels, taking into account the patient's age, are monitored. Three possible variants of the manifestation of pancreatopathy of terminal states are established in the form of: acute exocrine-type ischemic pancreatopathy, developing in young patients under 30 years of age, which manifests itself only as hyperamylasemia without hyperglycemia; acute ischemic pancreatopathy of the combined type that develops in patients of the middle age group from 30 to 60 years, which manifests itself as hyperamylasemia with hyperglycemic syndrome; acute ischemic pancreatopathy of the endocrine type, which develops in patients of the age group over 60 years, which manifests itself only as hyperglycemic syndrome.EFFECT: method allows accurate, simple and affordable diagnosis of acute ischemic damage to the pancreas, timely establish the diagnosis of this disease in the hospital by assessing the complex of the most significant indicators.1 cl, 3 ex

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Stamper for some insulin applicators

NºPublicación: SK142018U1 01/03/2019

Solicitante:

BUDAY MARIAN [SK]

Resumen de: SK142018U1

Značkovač pozostáva z dvoch perforovaných plochých kotúčov (1) a (2) navzájom spolu prepojených pružnými členmi (3). Prvý plochý kotúč (1) je fixovaný na teleso inzulínového aplikátora (5). Druhý plochý kotúč (2) je vratne pohyblivý v smere osadenia aplikačnej ihly (6). Čelná plocha pohyblivého plochého kotúča (2) je vybavená značkovacím prvkom (4).

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HYPERSPECTRAL TECHNOLOGY FOR ASSESSING AND TREATING DIABETIC FOOT AND TISSUE DISEASE

NºPublicación: US2019059787A1 28/02/2019

Solicitante:

HYPERMED IMAGING INC [US]

US_2015133754_A1

Resumen de: US2019059787A1

This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction, obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

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MEASURING APPARATUS AND MEASURING METHOD

NºPublicación: WO2019039269A1 28/02/2019

Solicitante:

RICOH CO LTD [JP]
UNIV TOHOKU [JP]
KASAHARA RYOSUKE [JP]
MATSUURA YUJI [JP]

Resumen de: WO2019039269A1

A measuring apparatus includes a light source configured to output light in a mid-infrared region, a detector configured to irradiate a measuring object with the light output from the light source and detect reflected light reflected by the measuring object, and a blood glucose level measuring device configured to measure a blood glucose level of the measuring object. A wavenumber between a plurality of absorption peak wavenumbers of glucose is used as a blood glucose level measuring wavenumber for measuring the blood glucose level.

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APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

NºPublicación: US2019059793A1 28/02/2019

Solicitante:

MEDTRONIC MINIMED INC [US]

US_2019076068_A1

Resumen de: US2019059793A1

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

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DEVICE, METHOD, AND PROGRAM FOR PREDICTING HYPOGLYCEMIA AND DEVICE, METHOD, AND PROGRAM FOR PRODUCING HYPOGLYCEMIA PREDICTING MODEL

NºPublicación: WO2019039808A1 28/02/2019

Solicitante:

POSTECH ACAD IND FOUND [KR]

Resumen de: WO2019039808A1

A device for predicting hypoglycemia according to one embodiment of the present invention is a hypoglycemia predicting device using blood sugar-related information to predict the occurrence of postprandial hypoglycemia, wherein the blood sugar-related information includes blood sugar at a reference time, a blood sugar change rate over a duration from an eating time to a postprandial peak blood sugar level time, a blood sugar change rate over a duration from a postprandial peak blood sugar level time to a reference time, and a blood sugar change rate over the reference time.

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CONTINUOUS GLUCOSE MONITORS AND RELATED SENSORS UTILIZING MIXED MODEL AND BAYESIAN CALIBRATION ALGORITHMS

NºPublicación: WO2019038661A1 28/02/2019

Solicitante:

DEXCOM INC [US]

Resumen de: WO2019038661A1

A method for monitoring blood glucose levels includes receiving a time-varying electrical signal from an analyte sensor during a temporal phase of a monitoring session and selecting a calibration model from a plurality of calibration models. The selected calibration model includes one or more calibration model parameters. The method further includes estimating at least one of the one or more calibration model parameters of the selected calibration model based on at least the time-varying electrical signal during the temporal phase and estimating the blood glucose level of the user based on the selected calibration model and the at least one estimated parameter. An apparatus and non-transitory computer readable medium can carry out similar functionality.

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APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

NºPublicación: US2019059794A1 28/02/2019

Solicitante:

MEDTRONIC MINIMED INC [US]

US_2019076068_A1

Resumen de: US2019059794A1

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

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MEDICAL DEVICES AND RELATED EVENT PATTERN PRESENTATION METHODS

NºPublicación: US2019066831A1 28/02/2019

Solicitante:

MEDTRONIC MINIMED INC [US]

Resumen de: US2019066831A1

Medical devices and related patient management systems and methods are provided. A method of presenting information pertaining to operation of a medical device involves obtaining historical glucose measurement data for a patient from a database, identifying, based on the historical glucose measurement data, a first set of event patterns within respective ones of a plurality of monitoring periods, obtaining an adjusted set of glucose measurement data determined based on the historical glucose measurement data and an uncertainty metric associated with the historical glucose measurement data, identifying, based on the adjusted set of glucose measurement data, one or more event patterns within respective ones of the plurality of monitoring periods, and generating a graphical user interface display comprising an event detection region based at least in part on the first plurality and the one or more sets of event patterns.

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SYSTEMS AND METHODS FOR DYNAMICALLY AND INTELLIGENTLY MONITORING A HOST'S GLYCEMIC CONDITION AFTER AN ALERT IS TRIGGERED

NºPublicación: US2019059826A1 28/02/2019

Solicitante:

DEXCOM INC [US]

CN_109480861_A

Resumen de: US2019059826A1

Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

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TRANSCUTANEOUS ANALYTE SENSOR

NºPublicación: US2019059730A1 28/02/2019

Solicitante:

DEXCOM INC [US]

US_2017231497_A1

Resumen de: US2019059730A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

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CHEMICAL MODULATION OF NERVES INNERVATING THE LIVER

Nº publicación: US2019059969A1 28/02/2019

Solicitante:

METAVENTION INC [US]

US_2019069942_A1

Resumen de: US2019059969A1

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

traducir

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