Resumen de: US2021317491A1

In an aspect, the disclosure provides methods for making neurotransmitters in a host organism. The neurotransmitters can be cannabinoids and derivatives of cannabinoids. The host cells can be microalgae, fungi or other host cells. In a related aspect, the disclosure provides host cells engineered to have biochemical pathways for making neurotransmitters such as cannabinoids.

Resumen de: WO2020115692A1

The present invention relates to a microalgal strain of the species Nannochloropsis gaditana. More in particular, the present invention relates to a microalgal strain of the species Nannochloropsis gaditana, characterised by a mutation of an enzyme involved in the biosynthesis of chlorophyll that changes the physiology thereof with respect to the wild-type strain of the same species. In particular, thanks to said mutation, microalgae are formed which, with respect to the wild-type strain of the same species, have a lower chlorophyll content and a reduced capacity to absorb visible radiation (light). Further, the present invention relates to a process for the production of lipids through the cultivation of said mutated Nannochloropsis gaditana strain. The lipids thus obtained can be used as synthesis intermediates, particularly in the so-called "green-chemistry" sector or in the production of biofuels.

Resumen de: WO2020117128A1

The present invention relates to methods of metabolic engineering cells to increase their ability to compete with contaminating microorganisms without the need for antibiotics. More particularly, the invention provides methods to engineer cyanobacteria to utilize melamine as nitrogen source, phosphite as phosphorous source, optionally also utilizing NADP+ over NAD+, and also provides genetically engineered cyanobacteria made using such methods. In a particular embodiment, the genetically engineered cells are cyanobacterium transformed by at least one polynucleotide molecule comprising heterologous melamine utilization pathway genes, atzD, trzE, DUR1,2, trzC, guaD and triA operably linked to at least one promoter and/or comprising a further phosphite dehydrogenase (ptxD ) gene.

Resumen de: WO2021200450A1

Provided are a culture apparatus and a culture method with which microalgae can be cultured satisfactorily. The culture apparatus (10) includes a plurality of culture tanks (12) and a water storage tank (14), and cultures microalgae in a culture solution. Each of the plurality of culture tanks (12) has a translucent accommodating portion (18) containing the culture solution and microalgae. The volumes of the accommodating portions (18) of the plurality of culture tanks (12) are different from each other. The water storage tank (14) has a translucent water storage unit (42) for storing a stored water (W). The plurality of culture tanks (12) are selectively arranged in the water storage unit (42).

Resumen de: US2021309961A1

Current invention relates to biotechnology sphere and particularly describes the novel approach for non-attached biofilm-like aggregates fabrication in vitro under artificial microgravity environment conditions. Non-attached aggregates are grown under magnetic levitation conditions achieved by placing microorganisms suspension in paramagnetic nutrient medium in inhomogeneous magnetic field created by specifically developed permanent magnets. The invention method can produce biofilm-like aggregates from protozoa, fungi, microalgae, Gram-positive or Gram-negative bacteria and/or a consortium. The presented technology can be used for development of medications for treatment of chronic infections, antiseptics and solutions for surfaces, as well as in other applications requiring the use of non-attached biofilm-like aggregates model.

Resumen de: WO2021195712A1

The technology relates to a method for producing a transformed and fully-segregated cyanobacteria, the method comprising incubating the cyanobacteria and a nucleic acid comprising a selectable marker under conditions suitable for transformation of the cyanobacteria with the nucleic acid; further incubating the cyanobacteria in growth media under conditions suitable for recovery of the cyanobacteria; and selecting the transformed and fully-segregated cyanobacteria using a selection agent.

Resumen de: WO2021200449A1

A culture device by which microalgae can be satisfactorily cultured using a simple structure while suppressing an increase in energy consumption, and a culture method. A main body (12) of this culture device (10) comprises an accommodation part (16) which accommodates contents (M) and to which gas is supplied. The inner wall faces of the accommodation part (16) are joined together to form a joined part (18) which extends along the gas supply direction. A guide part (20) and a circulation part (22), which are adjacent to each other across the joined part (18), are each along the extending direction of the joined part (18) and communicated with each other via a guide part inlet (38) and a guide part outlet (40). A gas supply port (26) enables gas supply toward the guide part (20).

Resumen de: WO2021200451A1

The present invention can: efficiently and readily produce glucose from microalgae that accumulate starch in their cells; and obtain ethanol. During a preparation step of the glucose production method, microalgae are prepared on which a saccharifying enzyme acts on starch accumulated inside the microalgae cells, without disrupting the cell walls. In a saccharification step, starch inside the cells is saccharified and glucose is generated, by adding a saccharifying enzyme to the microalgae without a disruption treatment. The ethanol production method has a step in which, after the saccharification step, the glucose undergoes alcoholic fermentation and ethanol is generated.

Resumen de: US2021301309A1

In an aspect, the disclosure provides methods for making neurotransmitters in a host organism. The neurotransmitters can be cannabinoids and derivatives of cannabinoids. The host cells can be microalgae, fungi or other host cells. In a related aspect, the disclosure provides host cells engineered to have biochemical pathways for making neurotransmitters such as cannabinoids.

Resumen de: KR20210117394A

본 발명은 미세조류를 이용한 공기 정화기에 관한 것으로서, 내부에 유동공간이 마련되며, 상기 유동공간으로 외기가 유입될 수 있도록 유입구 및 배출구가 형성된 본체와, 상기 본체에 설치되어 외기를 상기 유입구로 유입되어 상기 배출구로 배출되도록 강제송풍시키는 송풍유닛과, 상기 유동공간 내에 설치되며, 내부에 미세조류가 생장하는 배양액이 수용되는 저수공간이 마련된 배양수조와, 상기 유동공간으로 유입된 외기 중 이산화탄소를 소비하여 산소가 발생되도록 상기 미세조류가 광합성할 수 있게 상기 배양수조 내에 광을 조사하는 광원부가 마련된 배양유닛과, 상기 유동공간의 유입된 외기 중 이물질을 걸러낼 수 있도록 상기 배양수조에 수용된 배양액 중 일부를 상기 유동공간을 통과하는 외기와 접촉시킨 다음, 상기 배양수조로 회귀시키는 접촉유닛을 구비한다. 본 발명에 따른 미세조류를 이용한 공기 청정기는 미세조류가 공기 중 이산화탄소를 소비하여 산소를 공급해주고 미세조류 배양액에 의해 공기 중 분진 등 미세물질이 제거될 수 있어 공기 오염이 저감될 수 있고 또 공기 중 산소 농도가 높아질 수 있다.

Resumen de: PL433342A1

Przedmiotem zgłoszenia jest fotobioreaktor do produkcji mikroglonów olejowych który charakteryzuje się tym, że stanowi go rura (1) wykonana z przezroczystego poliwęglanu i zakończona na dole stożkiem, w którym umieszczone są króciec (2) doprowadzający pożywkę, króciec (3) odprowadzający medium hodowlane, króciec (4) doprowadzający sprężone powietrze oraz połączenie (5) zakończone ruchomym korkiem (6) znajdującym się w rurze (1). Współosiowo do przezroczystej rury (1) zainstalowana jest wewnętrzna dwuścienna rura (7) zaizolowana termicznie za pomocą próżni w dwuściennej obudowie, przy czym we wnętrzu rury (7) zamocowane są przewody (8) z czynnikiem chłodzącym lub grzejącym podłączone do źródła energii (9).

Resumen de: WO2020099590A1

The invention relates to a device (10) for producing microalgae, comprising a basin (12) containing an aqueous medium and a movable support (14) capable of receiving a cell culture made up of algae cells, which movable support is immersed at least partially in the aqueous medium and has at least a first portion and a second portion, characterised in that the movable support is arranged in the basin such that the first portion is exposed directly to a main light source (18) and forms an exposure section (24), and the second portion is not exposed directly to the main light source (18) and forms an inhibition section (26), the device (10) further comprising a secondary light source (28) designed to emit actinic light in the direction of the inhibition section (26) so as to inhibit the pigment synthesis of at least some of the algae cells. The invention also concerns a method for producing microalagae.

Resumen de: PH12020050063A1

The invention relates to the protocol for harvesting of microalgae, Chaetoceros calcitrans by manipulation of electrolytic flocculator settings. The harvesting system comprised of a holding tank for the microalgae, a DC power supply with variable voltage selector, ammeter and voltmeter. The best settings of 6/6 units Al/Pb probes with voltage selector set at point 1 to supply 3 volts to complete the electrolytic cell. The Pb in the paste was reduced by 97 pcnt with values of 34.27 ñ 0.39 ppm with 0 - 0.24 ppm Pb in the effluent discharge. The Pb content in secondary live food, Artemia salina was further reduced by 78 pcnt based on feeding trials with 7.8 ñ 5.1 ppm Pb content. This system will be beneficial to hatcheries for use onsite due to its simplicity and affordability.

Resumen de: WO2021183354A1

The disclosure provides methods and systems to produce lipid products from a gaseous substrate using a two-stage fermentation process. The method comprises providing a gaseous substrate comprising CO, CO2 or H2 or mixtures thereof, to a first bioreactor containing a culture or one or more microorganisms and fermenting the substrate to produce acetate. The acetate from the first bioreactor is then provided to a second bioreactor, where it is used as a substrate for fermentation to lipids by one or more microalgae. Tail gas from the second bioreactor is recycled to the first bioreactor.

Resumen de: US2021284941A1

This apparatus (30) for the production of microalgae comprises a vessel (1) intended to receive a culture medium of the microalgae, and a lighting device (6) intended to be positioned in the vessel inside the culture medium. The lighting device (6) is configured to emit light at least in a range of wavelengths useful for the photosynthesis of the microalgae. The apparatus comprises a control system (15) for automatically controlling a power supply of the lighting device (6) so as to adjust the output light intensity of the lighting device (6) according to the concentration of microalgae in the vessel (1).

Resumen de: US2021284952A1

Methods of culturing microalgae in acetate toxicity conditions to induce the uptake of acetate, control contamination, increase the metabolic rate, increase the respiration rate, increase the accumulation of lipids, and decreasing the accumulation of protein are disclosed. Embodiments include methods of controlling the internal microalgae cell acetate concentration by manipulating the culture pH and residual acetate concentration.

Resumen de: US2021285022A1

In an aspect, the disclosure provides methods for making neurotransmitters in a host organism. The neurotransmitters can be cannabinoids and derivatives of cannabinoids. The host cells can be microalgae, fungi or other host cells. In a related aspect, the disclosure provides host cells engineered to have biochemical pathways for making neurotransmitters such as cannabinoids.

Resumen de: WO2021180713A1

The invention relates to a system (1) for producing microalgae in the form of biofilm, comprising a frame (100), a motor (200), at least one support (300) and a ply (400) designed to receive the biofilm and in which: • the frame (100) is configured to support the motor (200), • the motor (200) is configured to impart a rotational movement on at least one support (300); • the at least one support (300) is configured to have a rotational movement about an axis of rotation and to support and impart the rotational movement on the ply (400); • the ply (400) is configured to at least partially surround the at least one support (300), characterized in that the support (300) is configured to have a non-negative buoyancy in a liquid (2).

Resumen de: US2021277431A1

In an aspect, the disclosure provides methods for making neurotransmitters in a host organism. The neurotransmitters can be cannabinoids and derivatives of cannabinoids. The host cells can be microalgae, fungi or other host cells. In a related aspect, the disclosure provides host cells engineered to have biochemical pathways for making neurotransmitters such as cannabinoids.

Resumen de: AU2020223331A1

Some embodiments include a microalgae culturing system including a bioreactor adapted to propagate microalgae in a culture solution using in combination at least one of natural and artificial light, and at least one nutrient including at least a carbon source, where the microalgae are freely suspended in and form part of the culture solution. A microalgae feed source is coupled to the bioreactor and a first controller between a water conditioning assembly and the bioreactor. The water conditioning assembly is coupled as an input of supply water to the bioreactor, and configured to condition the supply water to a specified purity that enables substantially unhindered growth of the microalgae in the culture solution to a specified concentration, and the first controller is configured to control supply of the microalgae feed source to the bioreactor.

Resumen de: WO2020089703A1

The present invention relates to transgenic microalgae for the production of cell wall degradative enzymes having a heat-stable cellulolytic activity (HCWDEs) and their relative uses in the biodegradation of cellulose or lignocellulose sources in the industrial field.

Resumen de: US2021269373A1

A soil restoration system including a plurality of dry particles, each particle inoculated with dehumidified biological material including at least one species of cyanobacteria, the cyanobacteria being physically supported by the particles, and the cyanobacteria being activatable by a threshold amount of moisture so that when the cyanobacteria is activated at an application site, the cyanobacteria multiplies to form a biological soil crust capable of facilitating plant seed catchment and vascular plant germination at the application site.

Resumen de: WO2021170839A1

Use of aprotinin as a carrier to produce a recombinant protein, polypeptide or peptide in algae The present invention relates to the use of aprotinin as a carrier to produce a recombinant protein, polypeptide or peptide in algae, in particular microalgae, wherein aprotinin and said recombinant protein, polypeptide or peptide are fused together to form a fusion protein. It also relates to a method to produce a recombinant protein, polypeptide or peptide in algae, wherein said method comprises genetic transformation of algae, in particular microalgae, with a recombinant nucleic acid sequence encoding a fusion protein, wherein said fusion protein comprises aprotinin and said recombinant protein, polypeptide or peptide. It further relates to a recombinant algae comprising a recombinant nucleic acid sequence encoding a fusion protein, wherein said fusion protein comprises aprotinin and a recombinant protein, polypeptide or peptide. The use of said recombinant algae, for producing said fusion protein is also contemplated.

Resumen de: WO2021170754A1

The present invention concerns a recombinant microalgae comprising a nucleic acid sequence encoding a recombinant peptide of KTTKS (SEQ ID N°1); a recombinant peptide, polypeptide or protein consisting in repeated units of SEQ ID N°1; or a derivative thereof, said nucleic acid sequence being located in the chloroplast genome of microalgae. It also relates to a method for producing a recombinant peptide of SEQ ID N°1; a recombinant peptide, polypeptide or protein consisting in repeated units of SEQ ID N°1; or a derivative thereof, wherein said method comprises the chloroplast genome transformation of a microalgae with a nucleic acid sequence encoding said recombinant protein, polypeptide or peptide. It further relates to the use of said recombinant peptide, polypeptide or protein for the cosmetic industry.

Resumen de: EP3872088A1

The present invention relates to the use of aprotinin as a carrier to produce a recombinant protein, polypeptide or peptide in algae, in particular microalgae, wherein aprotinin and said recombinant protein, polypeptide or peptide are fused together to form a fusion protein. It also relates to a method to produce a recombinant protein, polypeptide or peptide in algae, wherein said method comprises genetic transformation of algae, in particular microalgae, with a recombinant nucleic acid sequence encoding a fusion protein, wherein said fusion protein comprises aprotinin and said recombinant protein, polypeptide or peptide. It further relates to a recombinant algae comprising a recombinant nucleic acid sequence encoding a fusion protein, wherein said fusion protein comprises aprotinin and a recombinant protein, polypeptide or peptide. The use of said recombinant algae, for producing said fusion protein is also contemplated.