CORONAVIRUS: DIAGNÓSTICO Y TERAPIA EN HUMANOS

VolverVolver

Resultados 468 resultados LastUpdate Última actualización 01/12/2022 [15:25:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 60 días/Published applications in the last 60 days



Página1 de 19 nextPage   por página


COMPOSITIONS FOR TREATING SARS-COV2 INFECTION

NºPublicación: EP4094756A1 30/11/2022

Solicitante:

HIRSCH APOTHEKE WOLFGANG SCHOLZ E K [DE]

EP_4094755_A1

Resumen de: EP4094756A1

The present invention relates to compositions comprising hypericin and/or pseudohypericin for use in a method for treating or preventing an infection with SARS-CoV2 in a human subject in need thereof. The present invention further relates to (mouth wash, gargle solution, nose spray, inhalant, lozenge, tablet, chewing gum, injection solution comprising hypericin and/or pseudohypericin.

traducir

USE OF BENZOATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS

NºPublicación: EP4094758A1 30/11/2022

Solicitante:

ACAD OF MILITARY MEDICAL SCIENCES [CN]

WO_2021147272_A1

Resumen de: EP4094758A1

Disclosed are the use of a benzoate compound as shown in formula I, a geometric isomer thereof, a pharmaceutically acceptable salt thereof and/or a solvate thereof or a hydrate thereof, and a pharmaceutical composition containing the above-mentioned compound in the prevention and treatment of SARS-CoV-2 infections.

traducir

COMPOSITION AND METHODS OF RNAi PROPHYLACTICS AND THERAPEUTICS FOR TREATMENT OF SEVERE ACUTE RESPIRATORY INFECTION CAUSED BY 2019 NOVEL CORONAVIRUS (2019-nCoV)

NºPublicación: EP4093511A2 30/11/2022

Solicitante:

SIRNAOMICS INC [US]

KR_20220151612_PA

Resumen de: WO2021151096A2

Compositions and methods for development of potent siRNA therapeutics for prevention and treatment of Corona Virus (2019-nCoV; COVID-19) infections are provided. The compositions include a pharmaceutical composition comprising siRNA cocktails that target critical viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Administration methods for prevention and treatment are provided, including airway instillation, subcutaneous injections and nebulizer aerosolization.

traducir

USE OF INTERFERON IN PREPARING DRUG FOR PREVENTING CORONAVIRUS INFECTION OR PREVENTING DISEASE CAUSED BY CORONAVIRUS INFECTION

NºPublicación: EP4094774A1 30/11/2022

Solicitante:

SHANGHAI GANYI MEDICAL BIOTECHNOLOGY INC [CN]
MENG ZHONGJI [CN]
LL HAI [CN]

Resumen de: EP4094774A1

Disclosed are a use of an interferon in preparing a drug for preventing novel coronavirus SARS-CoV-2 infection or a disease COVID-19 caused by the novel coronavirus infection, and a drug for preventing novel coronavirus infection or preventing a disease COVID-19 caused by the novel coronavirus infection.

traducir

MEDICAL DEVICE FOR PREVENTION OF COVID 19

NºPublicación: RO136082A2 29/11/2022

Solicitante:

ASOCIATIA FORUMUL INVENTATORILOR ROMANI IASI [RO]

Resumen de: RO136082A2

The invention relates to a process for preparing a pharmaceutical antiviral formulation as an aqueous product applicable onto nasal mucosa. According to the invention, the process consists of the following steps: harvesting fresh wild garlic bulbs, possibly preserved by freeze-drying or cryogenic means, immersing them in a mixture of ethanol aqueous solution and NaCl aqueous solution 30%, in a volume ratio of 2:1, for 3...5 min, separating the juice from the flesh by pressing on a stainless steel sieve, mixing the so filtered juice with a saline solution of NaCl 4...5%, in a volume ratio of 4:1, settling for 10...15 min, possibly followed by centrifugation at 1800 rpm, for 20 min, after which the clear supernatant is taken over by suction, in an amount of 2 ml, to be applied as drops on the lower and medium nasal cavity.

traducir

Technology for histological detection of sars-cov-2 virus infection using non-linear laser scanning microscopy

NºPublicación: HU2100204A2 28/11/2022

Solicitante:

FEMTONICS KFT [HU]
HCEMM NONPROFIT KFT [HU]
SEMMELWEIS EGYETEM [HU]

METHOD OF BREATH SCREENING OF VIRAL INFECTION

NºPublicación: CA3160350A1 25/11/2022

Solicitante:

TEKNOSCAN SYSTEMS INC [CA]

Resumen de: CA3160350A1

An apparatus for detecting Covid-19 infection in a subject, the apparatus comprising (a) a sampling apparatus for collecting a breath sample from a subject (b) An analyzer, comprising an ion mobility spectrometer (IIVIS), for receiving the sample from the sampling apparatus and for determining the presence in the sample of Volatile Organic Compounds (VOCs) indicative of Covid-19, the VOCs comprising at least three compounds selected from the group consisting of C1-C3 alcohols, C2-C8 aldehydes, C3-C4 ketones and C4-C6 alkyl esters.

traducir

METHODS FOR TREATING, AMELIORATING OR PREVENTING INFECTIONS USING DRUG AND VACCINATION COMBINATION TREATMENT

NºPublicación: US2022370589A1 24/11/2022

Solicitante:

TOPELIA AUSTRALIA PTY LTD ACN 652 771 670 [AU]

Resumen de: US2022370589A1

In alternative embodiments, provided are methods for treating, ameliorating, decreasing the chances of having any adverse effects from, decreasing the severity of adverse effects from, or preventing an infection by administration of an antibiotic and/or an anti-viral drugs and a vaccine directed to a causative agent of the infection and/or an attenuated and/or a live, viable or infectious causative agent of the infection. In alternative embodiments, the infection is bacterial or viral. In alternative embodiments, the viral infection is a coronavirus infection such a Covid-19 infection. In alternative embodiments, methods as provide herein prevent or decrease the prevalence or severity of “vaccine breakthrough infections” after vaccination, where external mutants of COVID-19 infect patients in spite of the fact that they have undergone immunization, for example, to prevent a mutant or variant COVID-19 infection. In alternative embodiments, an antiviral combination administered in coordination with a vaccine comprises PF-07321332 or PAXLOVID™ and/or ritonavir, or ivermectin, doxycycline and a zinc or a zinc salt. In alternative embodiments, methods as provided herein are used to prevent in vivo mutations of such mutant infectious agent to enhance the efficacy of an administered vaccination; in other words, methods as provided herein are used to prevent in vivo replication of an acquired viral mutant or variant infectious agent, and thus also prevents ongoing mutations of

traducir

TAQ-NEQSSB POLYMERASE, THE METHOD OF ITS OBTAINING, RECOMBINANT PLASMID, PRIMERS, AND APPLICATION OF THE POLYMERASE.

NºPublicación: WO2022245230A1 24/11/2022

Solicitante:

INST BIOTECHNOLOGII I MEDYCYNY MOLEKULARNEJ [PL]

Resumen de: WO2022245230A1

The subject of the invention is a TaqPol-NeqSSB polymerase and its cloning method. Furthermore, the subject of the invention is an isolated recombinant plasmid, primers, and the application of the polymerase to replicate specific sequences of the SARS CoV-2 virus.

traducir

ELECTROCHEMICAL DIAGNOSTIC SYSTEM

NºPublicación: US2022373498A1 24/11/2022

Solicitante:

PERSOWN INC [US]

US_2022373510_PA

Resumen de: US2022373498A1

Described are devices, systems, kits, methods, and techniques for analyzing test fluids to determine presence, absence, or concentration of analytes in the test fluids and useful for performing diagnostic testing, such as to quickly identify whether or not an individual may have a particular disease or condition, such as infection by SARS-CoV-2 or a SARS-CoV-2 variant or vaccine-induced immunity or natural immunity to infection by SARS-CoV-2 or a SARS-CoV-2 variant. The devices, systems, kits, methods, and techniques described herein can be used to detect analytes in body fluids using a functionalized electrochemical test strip and potentiostatic measurements, allowing for prompt identification of whether or not an individual has a particular disease or condition, such as in a period of 5 minutes or less.

traducir

ANTIBODY CONJUGATED NANOPARTICLE ASSAY AND TREATMENT FOR SARS-CoV-2

NºPublicación: US2022370958A1 24/11/2022

Solicitante:

ARIZONA BOARD OF REGENTS ON BEHALF A ARIZONA STATE UNIV [US]
HALBERD CORP [US]

Resumen de: US2022370958A1

An embodiment provides a method for treatment of a viral antigen for the COVID-19 virus, including: obtaining a body fluid from a patient; introducing the body fluid to at least one binding antibody, wherein the at least one binding antibody binds to an antigen of the SARS-CoV-2 spike (S) protein and comprises a conjugated metal; forming a viral antigen-antibody complex; and removing the viral antigen-antibody complex from the body fluid using a radiofrequency method; and returning the body fluid to the patient. Other aspects are described and claimed.

traducir

COVID-19 EXPOSURE DETECTOR

NºPublicación: US2022369733A1 24/11/2022

Solicitante:

ZORE TERRY [US]

Resumen de: US2022369733A1

The disclosure is the only product of its kind with the potential to curb the spread of contagious aerosolized disease via widely accessible and versatile disc that complements the requirement for wearing a face mask. CODIS is uniquely designed to enhance the contact tracing process of infectious diseases and serves as a proactive medium for identifying disease exposure in real-time. The disclosed pathogen indicator device includes a reagent configured to trigger a chemical reaction based on an exposure to a predetermined pathogen. The disclosure also includes a mask substrate configured to receive the reagent on a front side and to bond therewith on a backside thereof. The disclosure further includes a seal for the substrate and the reagent, the seal configured to provide a prophylactic temporary protection from the predetermined pathogen.

traducir

METHODS FOR TREATING POST INFECTIOUS AUTOIMMUNE DIABETES

NºPublicación: US2022372146A1 24/11/2022

Solicitante:

PROVENTION BIO INC [US]

Resumen de: US2022372146A1

Provided herein are a method of treating type 1 diabetes (T1D) post SARS-CoV-2 infection. In some embodiments, such method can include administering to a subject in need thereof a 12-day course of teplizumab at a total dose of more than about 9000 μg/m2.

traducir

SARS-COV-2 RECOMBINANT N PROTEIN, AND PREPARATION METHOD AND PURIFICATION METHOD THEREFOR

NºPublicación: US2022372083A1 24/11/2022

Solicitante:

SHENZHEN YHLO BIOTECH CO LTD [CN]

WO_2021169433_A1

Resumen de: US2022372083A1

Provided are a recombinant N protein of SARS-CoV-2 and methods for preparing the same and for purifying the same. The recombinant N protein of SARS-CoV-2 has an N protein sequence, wherein each of both ends of the N protein sequence are linked to an oligolysine fragment. An expression method for the recombinant N protein includes: a. providing a sample including the recombinant N protein; and b. performing cation exchange chromatography resin purification treatment at least once, and collecting breakthrough substance. The method may effectively improve the expression purity of the recombinant N protein.

traducir

SARS-COV-2 SUBUNIT AND VARIANT VACCINES

NºPublicación: US2022372080A1 24/11/2022

Solicitante:

IBIO INC [US]

WO_2022226201_PA

Resumen de: US2022372080A1

The present invention includes an immunogenic protein, constructs, vectors, and methods of making, comprising at least 90% amino acid identity to at least one antigenic peptide selected from: a coronavirus Receptor Binding Domain (RBD), coronavirus a Receptor Binding Motif (RBM) of a coronavirus spike protein, a coronavirus spike protein N-terminus, a nucleocapsid protein, one or more T cell epitopes from a coronavirus spike protein, or one or more T cell epitopes from a coronavirus nucleocapsid protein, or combination thereof. In one example, the at least one antigenic peptide is positioned at, at least one of, the N-terminus, the C-terminus, or in a loop region of the carrier protein or peptide tag.

traducir

Tennis Balls Sanitizing Machine

NºPublicación: US2022370664A1 24/11/2022

Solicitante:

SINGH SHASHWAT [US]

Resumen de: US2022370664A1

COVID-19 and many other infectious diseases like Flu can spread through by touch. Tennis player exchange the same balls multiple times during the practice or game. For student's safety schools and colleges currently sanitize the balls manually which is a tedious and time taking job. This invention sanitizes the bunch of tennis balls in one go with the push of a buttons and a Knob which control the speed of motor vibration.

traducir

ANTIVIRAL ESSENTIAL OIL COMPOSITIONS

NºPublicación: US2022370535A1 24/11/2022

Solicitante:

ERDOGMUS HUESEYIN [KR]

WO_2022093141_A1

Resumen de: US2022370535A1

Disclosed are antiviral essential oil compositions including one or more essential oils, such as styrax oil and resinoid, gurjun balsam oil, olibanum resinoid, nootka tree oil, vetiver oil, jatamansi oil, sandalwood oil, myrrhe oil, agarwood oil, copaiba balsam oil, ginger oil, curcuma oil, clary sage absolute, cypriol oil, rosemary oil, eucalyptus globulus, tea tree oil, patchouly oil, benzyl benzoate, vertofix(acetylated cedarwood oil), benzyl salicylate, benzyl cinnamate, cinnamyl benzoate, cinnamyl cinnamate, dihydroambrettolide, galaxolide, L-muscone, nootkatone, vetiveryl acetate, sclareol. The use of discovered fragrance molecules and essential oils alone or combination provides beneficial antiviral effects, especially for SARS-CoV-2 (COVID-19).

traducir

CLEAR-FACED, VIRUS PROTECTION FACE MASK FOR IMPROVED FACIAL RECOGNITION

NºPublicación: US2022370836A1 24/11/2022

Solicitante:

JOHNSON CHANCE S [US]
BARTELS KEVIN [US]
WILLIAMS ANDREA [US]

Resumen de: US2022370836A1

A face shield of a face mask has two or more openings for attachment of air filters (e.g., COVID-19, T70 or T90 air filters). The two or more openings face towards the ground being substantially perpendicular to the nose and the lip of the face. A nose bridge attaches to a support fame and having a span from a first side of the nose over a top and to a second side of the nose. The nose bridge and connected portions of the support frame fully expose a front facing portion of the nose of the face.

traducir

MESSENGER RNA THERAPEUTICS AND COMPOSITIONS

NºPublicación: US2022370599A1 24/11/2022

Solicitante:

GREENLIGHT BIOSCIENCES INC [US]

Resumen de: US2022370599A1

In the various aspects and embodiments, this disclosure provides messenger RNA (mRNA) constructs for therapeutic delivery, as well as methods for making such mRNA constructs and pharmaceutical compositions comprising the same (including mRNA vaccine compositions). In still other aspects, the invention provides methods for treating patients by expression of therapeutic proteins, including for preventing or reducing probability of infection by, or illness involving, a virus. Exemplary viruses include coronaviruses (such as SARS-CoV-2 and variants therefore) and influenza viruses, among others.

traducir

SARS-CoV-2 POLYPEPTIDES

NºPublicación: US2022370601A1 24/11/2022

Solicitante:

MAYO FOUND MEDICAL EDUCATION & RES [US]

Resumen de: US2022370601A1

This document provides methods and materials related to selected severe acute respiratory distress coronavirus 2 (SARS-CoV-2) polypeptides. For example, this document provides vaccine compositions that contain one or more selected SARS-CoV-2 polypeptides provided herein and that have the ability to induce or increase immune responses against coronaviruses such as SARS-CoV-2 within a mammal (e.g., a human).

traducir

MULTIGENIC MVA-SARS-COV-2 VACCINE

NºPublicación: US2022370600A1 24/11/2022

Solicitante:

UNIV TEXAS [US]

Resumen de: US2022370600A1

The present invention includes compositions and methods of making and using an immunogenic protein for mucosal delivery comprising at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% amino acid identity to a multigenic coronavirus vaccine on a modified vaccinia ankara (MVA) vector that expresses a viral nucleoprotein (N) protein and a spike (S) protein.

traducir

SYNTHETIC pDNA VACCINES AGAINST COVID-19

NºPublicación: US2022370596A1 24/11/2022

Solicitante:

UNIV IMAM ABDULRAHMAN BIN FAISAL [SA]

Resumen de: US2022370596A1

A pDNA-based vaccine against SARS-CoV-2 and methods for preventing or treating COVID-19 using it.

traducir

Vaccines Against Coronavirus and Methods of Use

NºPublicación: US2022370598A1 24/11/2022

Solicitante:

INOVIO PHARMACEUTICALS INC [US]
WISTAR INST [US]

WO_2022236301_PA

Resumen de: US2022370598A1

Provided herein are methods of inducing an immune response against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) in a subject in need thereof by administering an immunogenic composition to the subject, wherein the subject exhibits: an increase in antigen-specific cellular immune response as measured by Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) assay relative to baseline; and/or an increase in neutralizing antibody response as measured by a pseudovirus neutralizing assay relative to baseline.

traducir

METHODS AND REAGENTS OF IMMUNOLOGICALLY DETECTING SARS-CoV-2

NºPublicación: US2022373546A1 24/11/2022

Solicitante:

FUJIREBIO KK [JP]

Resumen de: US2022373546A1

The present invention provides a method of immunologically detecting SARS-CoV-2, the method comprising detecting a SARS-CoV-2 N protein in a specimen taken from a subject by using the following antibodies (1) and (2): (1) a first antibody to a first epitope in a 306th to 339th amino acid region in the SARS-CoV-2 N protein, and (2) a second antibody to a second epitope in a 365th to 419th amino acid region in the SARS-CoV-2 N protein.

traducir

SARS-COV-2 SPIKE PROTEIN ANTIBODIES

Nº publicación: US2022372114A1 24/11/2022

Solicitante:

CURIA IP HOLDINGS LLC [US]

Resumen de: US2022372114A1

The present disclosure provides antibodies that bind to the SARS-CoV-2 spike protein, as well as compositions containing the same, and methods of making and using such a composition for treating, preventing, and/or detecting SARS-CoV-2 infection.

traducir

Página1 de 19 nextPage por página

punteroimgVolver