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Resultados 101 resultados LastUpdate Última actualización 22/02/2020 [17:52:00] pdf PDF

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days

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PROCESSES FOR PRODUCING CURED POLYMERIC PRODUCTS BY ADDITIVE MANUFACTURING

NºPublicación: US2020055237A1 20/02/2020

Solicitante:

BRIDGESTONE AMERICAS TIRE OPERATIONS LLC [US]

Resumen de: US2020055237A1

Disclosed herein are processes for production of a cured polymeric product which processes include using rubber particles to form a rubber layer, applying liquid binder to form a bound layer from the rubber layer, and curing, whereby repetition of steps allows for formation of additional layers and ultimately production of the cured polymeric product.

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DENTAL MODEL AND REUSABLE DIE ASSEMBLY FOR THERMOFORMING OF DENTAL ALIGNERS

NºPublicación: US2020055229A1 20/02/2020

Solicitante:

CARBON INC [US]

Resumen de: US2020055229A1

An assembly useful for thermoforming a dental aligner from polymer sheet material includes (a) a custom dental model having a planar bottom surface and a receptacle formed in said planar bottom surface; and (b) a reusable die removably received in said receptacle.

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Process for manufacturing a titanium zirconium alloy and its embodiment by additive manufacturing

NºPublicación: US2020055118A1 20/02/2020

Solicitante:

DJEMAI ABDELMADJID [FR]

KR_20190090692_A

Resumen de: US2020055118A1

The invention relates to a method for producing a composite material consisting of a metal and ceramic alloy, comprising steps of: producing a mixture of metal powder and ceramic powder, the particle size of the metal powder being micrometric and the particle size of the ceramic powder being nanometric; and exposing said mixture to a focused energy source that selectively fuses part of a bed of said powder mixture.

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SKIN PRINTER

NºPublicación: US2020054440A1 20/02/2020

Solicitante:

AGUILAR MARIELA [US]

US_2018221135_A1

Resumen de: US2020054440A1

A method includes forming a scaffold and seeding the scaffold with live cells; growing the cells in the scaffold; and 3D printing the cells into a living subject, where the cells continue to live in the living subject.

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COMPOSITE JOINT ARTHROPLASTY SYSTEMS AND METHODS

NºPublicación: US2020054346A1 20/02/2020

Solicitante:

TITANIUM FUSION TECH LLC [US]

WO_2018160481_A1

Resumen de: US2020054346A1

A prosthesis may have an articulating component formed via casting and a 3D printed bone anchoring component with a joint-facing side and a bone-facing side. The bone-facing side may have a bone engagement surface with a porous structure with pores selected to facilitate in-growth of the bone into the pores. The bone facing side may further have a surface layer of Titanium Dioxide nanotubes. The joint-facing side may be secured to the articulating component by melting Titanium nanoparticles at a temperature below the melting temperatures of the major constituents of the articulating component and/or the bone anchoring component, such as Cobalt, Chromium, and/or Titanium, so as to avoid significantly modifying the crystalline structures of the articulating component and/or the bone anchoring component. The melting temperature of the Titanium nanoparticles may be about 500° C.

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METHODS AND APPARATUSES FOR DESIGNING FOOTWEAR

NºPublicación: US2020057837A1 20/02/2020

Solicitante:

RSPRINT N V [BE]

US_2017068774_PA

Resumen de: US2020057837A1

Methods and apparatuses for designing custom footwear are disclosed. An apparatus for designing custom footwear may include a data collection system, a data processing system, and a manufacturing system, where the manufacturing system includes an additive manufacturing device. A method for designing custom footwear may comprise receiving user-specific data, generating a user model, identifying issues in the user model, determining corrective features, generating a custom footwear model, and manufacturing the custom footwear.

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A Thermoresponsive Hydrogel

NºPublicación: US2020054791A1 20/02/2020

Solicitante:

UNIV JOHANNESBURG WITWATERSRAND [ZA]

WO_2018142299_A1

Resumen de: US2020054791A1

This invention relates to thermoresponsive hydrogels. Particularly, the invention relates to a thermoresponsive hydrogel comprising copolymer polyethylene glycol (PEG)-polycaprolactone (PCL)-polyethylene glycol (PEG) and polypropylene fumerate (PPF). The thermoresponsive hydrogel may further comprise a poloxamer, particularly Pluronic F-127. The invention extends to a method of manufacturing thermoresponsive hydrogels, also extends to an ink for a three dimensional (3D) printer including the thermoresponsive hydrogels. The invention further extends to a thermoresponsive hydrogel for use in the treatment of a bone injury and/or a bone defect, and/or to a method of treating a bone injury and/or a bone defect. The thermoresponsive hydrogels may include dispersed therein an active pharmaceutical ingredient (API), preferably an API falling in the Biopharmaceutics Classification System (BCS) class II, further preferably a statin type drug, most preferably simvastatin.

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ZIRCONIA ARTICLE WITH HIGH ALUMINA CONTENT, PROCESS OF PRODUCTION AND USE THEREOF

NºPublicación: US2020055779A1 20/02/2020

Solicitante:

3M INNOVATIVE PROPERTIES CO [US]

WO_2018151995_PA

Resumen de: US2020055779A1

The invention relates to a porous zirconia article in particular for use in the dental or orthodontic field, the porous zirconia article comprising ZrO2: 80 to 87 wt. %,Y2O3: 3 to 5 wt. %, AI2O3: 10 to 14 wt. %, wt. % with respect to the weight of the porous zirconia article, the porous zirconia article being characterized by a BET surface from 15 to 100 m2/g. The invention also relates to a sintered zirconia article in particular for use in the dental or orthodontic field, the sintered zirconia article comprising ZrO2: 80 to 87 wt 5, Y2O3: 3 to 5 wt. %), AI2O3: 10 to 14 wt. %, wt. %) with respect to the weight of the porous zirconia article, the sintered zirconia article being characterized by a corundum crystal phase content of 7 to 12 wt. %>and a flexural strength of at least 2,000 MPa.

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METHOD OF PRODUCING THREE DIMENSIONAL AUTOLOGOUS FAT GRAFT USING HUMAN LIPOASPIRATE-DERIVED ADIPOSE TISSUE WITH MULTIPOTENT STEM CELLS AND BIOCOMPATIBLE CELLULOSE NANOFIBRILS

NºPublicación: WO2020035734A1 20/02/2020

Solicitante:

CELLHEAL AS [NO]

Resumen de: WO2020035734A1

Autologous 3D fat grafting and modification of adipose tissue lipoaspirate rich in stem cells with biocompatible cellulose nanofibrils (CNF) or collagen nanofibrils to achieve processable dispersion/emulsion which can be formed into a 3D shape(s) with desired porosity. 3D construct formed is further crosslinked either in situ at the implantation site or before implantation. Grafting can be performed in human or animal to correct soft tissue contour deformities in reconstructive and aesthetic surgery, including but not limited to injection, moulding, or 3D bioprinting. Biocompatible cellulose or collagen nanofibrils act as a dispersant/emulsifier of disintegrated lipoaspirate and provide shear thinning properties which make it possible to process dispersion into 3D shape yet provide porosity for nutrient diffusion and neovascularization. Invention further comprises a crosslinker(s) to provide construct's mechanical stability and ability to be transplanted as larger structure.

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SOLID DOSAGE FORM PRODUCTION

NºPublicación: WO2020035680A1 20/02/2020

Solicitante:

UNIV CENTRAL LANCASHIRE [GB]

Resumen de: WO2020035680A1

The present invention provides methods of preparing solid dosage form, particularly pharmaceutical dosage forms, using extrusion and 3D-printing, as well as the solid dosage form itself, the compositions used to make said items, uses of the solid dosage forms, and containers used in their preparation.

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In Vivo Live 3D Printing of Regenerative Bone Healing Scaffolds for Rapid Fracture Healing

NºPublicación: US2020055302A1 20/02/2020

Solicitante:

TEXAS A & M UNIV SYS [US]
UNIV TEXAS [US]

US_2017143831_PA

Resumen de: US2020055302A1

Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.

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SYSTEM AND METHOD FOR CREATING A FASTENING ARRANGEMENT USING ADDITIVE MANUFACTURING TECHNIQUES

NºPublicación: ES2743438T3 19/02/2020

Solicitante:

FISCHERWERKE GMBH & CO KG [DE]

DE_102015113807_A1

Resumen de: EP3132921A1

Verfahren und System zur Erstellung einer Befestigungsanordnung (1) mit einem Befestigungsgegenstand (2) an einem Befestigungsgrund (3). Erfindungsgemäß umfasst das System ein Sensorsystem (5) zur Erfassung von Situationsdaten (13) einer Befestigungssituation, ein Expertensystem (6) zur Erzeugung digitaler Elementdaten (14) eines Elements (15) zur Befestigung, und einen 3D-Drucker (7) zur Erzeugung des Elements (15).

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MICROFLUIDIC DELIVERY CARTRIDGE FOR USE WITH A MICROFLUIDIC DELIVERY DEVICE

NºPublicación: EP3609545A1 19/02/2020

Solicitante:

PROCTER & GAMBLE [US]

KR_20190126374_A

Resumen de: WO2018191044A1

A cartridge that is releasably connectable with a housing of a microfluidic delivery device is provided. The cartridge has a reservoir for containing a fluid composition and a microfluidic die in fluid communication with the reservoir. The microfluidic die is configured to dispense substantially all of the fluid composition in a horizontal direction or downward direction relative to horizontal. The cartridge also includes an air flow channel disposed below the reservoir. The air flow channel extends from a fan to an air outlet. The air flow channel comprises a first region disposed adjacent to a fan, a second region disposed adjacent to the air outlet, and a third region joining the first and second regions. At least the second region is angled upward to the air outlet, relative to horizontal.

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一种3D打印的仿生骨支架

NºPublicación: CN210077950U 18/02/2020

Solicitante:

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Resumen de: CN210077950U

本实用新型公开了一种3D打印的仿生骨支架,包括疏松支架核层和从内到外紧密嵌套且孔隙率依次减小的至少三层环状支架壳层。本实用新型提供的3D打印的仿生骨支架能够模拟人体骨骼外密内疏的结构,能够同时构建出外层致密的皮质骨和内层疏松多孔的松质骨,构建出来的骨骼能够同时达到良好的强度和拥有较好的营养供给。而且,该仿生骨支架采用3D打印技术制备,通过打印时负载生长因子,更有利于细胞的定植与生长,促进骨组织再生,促进骨的愈合。

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一种含有3D打印内填充件的左心耳封堵器

NºPublicación: CN210077769U 18/02/2020

Solicitante:

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Resumen de: CN210077769U

本实用新型涉及一种含有3D打印内填充件的左心耳封堵器,包括密封盘和垂直于密封盘的固定架,所述密封盘包括位于密封盘圆心的圆心安装件,所述密封盘包括若干根呈伞骨设置的由密封盘圆心径向辐射式设置的支撑筋,所述密封盘的支撑筋上设有一层密封膜,所述固定架与密封盘于密封盘的圆心安装件螺纹连接,所述密封盘的外圆设有一圈外圆安装圈,所述外圆安装圈与支撑筋的外端连接,所述外圆安装圈的外圆端面设有一圈安装凹槽,所述外圆安装圈的安装凹槽旋转安装一圈软性缓冲填充圈。

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一种生物墨水及其制备方法

NºPublicación: CN110801532A 18/02/2020

Solicitante:

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Resumen de: CN110801532A

本发明公开了一种用于3D生物打印的生物墨水及其制备方法。所述生物墨水包括如下质量百分比的组分:质量分数8%~20%的具有交联功能的亲水性高分子、质量分数10~20%的具有交联功能的水溶性酶、质量分数0.1%~1%的细菌纤维素、余量为无菌PBS溶液。生物打印墨水与细胞混合后即可用于3D打印,所用材料的剪切变稀性能,使得生物墨水挤出后具有自支撑的特点。并且所用材料细胞相容性很好,酶交联剂在生理温度(37℃左右)形成水凝胶,反应条件温和,对细胞无伤害,水凝胶支架在培养液中稳定性较好可以支持细胞增殖。

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一种3D打印水凝胶支架的方法

NºPublicación: CN110804193A 18/02/2020

Solicitante:

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Resumen de: CN110804193A

本发明涉及一种3D打印水凝胶支架的方法,该方法包括以下步骤:(1)将不饱和聚酯、不饱和聚酯重量1~2倍的多官能团丙烯酸酯、不饱和聚酯重量2~4倍的平均分子量为475的聚乙二醇甲醚甲基丙烯酸酯和不饱和聚酯重量0.1~0.5倍的光引发剂加入到不饱和聚酯重量1~2倍亲水溶剂中混合均匀,得到水凝胶溶液;(2)在水凝胶溶液中加入粘度调剂,调整粘度为3000~6000mPa.s;(3)将步骤2调整粘度的水凝胶溶液导入到3D打印机的注射器中,按照设定程序打印,得到初级水凝胶支架;然后将初级水凝胶支架在365nm紫外光照射下进行光固化,冷冻干燥,得到所述的水凝胶支架;本方法所制备的水凝胶支架具有良好的亲水性,促进细胞附着和增值的效果显著。

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一种有机包裹的磁纳米粒子复合骨支架及其制备方法

NºPublicación: CN110801536A 18/02/2020

Solicitante:

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Resumen de: CN110801536A

本发明属于骨支架材料领域,具体公开了一种有机包裹的磁纳米粒子复合骨支架,由包含有机改性的磁性纳米粒子、聚合物在于内的混合原料经选择性激光烧结得到;所述的有机改性的磁性纳米粒子包括磁性纳米粒子以及包覆在其表面的有机物。本发明创新地发现,有机物包覆的磁性纳米粒子与聚合物具有明显协同性,通过选择性激光烧结方法,可以明显改善得到的骨支架的性能,例如,改善得到的骨支架的疏水性、改善拉伸以及压缩强度,此外,还可改善其生物相容性,促进骨骼生长等性能。

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一种直写成型3D打印生物墨水的制备及其3D打印方法

NºPublicación: CN110787320A 14/02/2020

Solicitante:

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Resumen de: CN110787320A

本发明公开了一种直写成型3D打印生物墨水的制备及其3D打印方法。该3D打印生物墨水以纤维素纳米纤维为主体,将甲基丙烯酸酐接枝到主体链段合成纤维素纳米纤维甲基丙烯酸酯。利用纤维素纳米纤维水凝胶剪切变稀的特性和甲基丙烯酸酯聚合物可光固化的特点,制备出具有生物相容性高,力学性能强,无毒可降解,并具备结构取向性可引导生物细胞生长分化的能力的3D打印生物墨水。应用该3D打印生物墨水打印的生物仿生结构,适合生物细胞在其中粘附、增殖和分化,是理想的生物组织重建和修复替代物。

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一种基于3D打印技术的实验用兔子固定装置

NºPublicación: CN210056322U 14/02/2020

Solicitante:

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Resumen de: CN210056322U

本实用新型公开了一种基于3D打印技术的实验用兔子固定装置,该兔子固定装置由3D打印而成;其包括:一底座;其为矩形板状;一三角垫体,其活动安装于所述底座的顶面上;其为直角三角形,且直角端与底座的一端端部对齐设置;一头部固定装置,包括头部垫体、设于头部垫体上的头部固定件以及头部垫体上形成的头部开槽;腿部固定装置,包括前腿固定件和后腿固定件,其分别由两个腿部固定件组成,各组分设于三角垫体的中部和底座的另一端。本实用新型提供了一种基于3D打印技术的实验用兔子固定装置,其不仅可根据兔子大小进行调节而且固定效果好,本设计符合动物躯干结构、保证术中动物呼吸顺畅,提高术后动物的存活率。

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一种基于3D打印的带气囊的棘轮止动机械假肢

NºPublicación: CN210056356U 14/02/2020

Solicitante:

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Resumen de: CN210056356U

一种基于3D打印的带气囊的棘轮止动机械假肢,属于假肢技术领域。所述基于3D打印的带气囊的棘轮止动机械假肢,包括依次连接假肢手指部、假肢手掌部、假肢腕部、假肢小臂部和连接残肢部,假肢手指部包括相对设置的夹板一和夹板二,所述夹板一和夹板二的内侧均设有气囊,所述夹板一与齿轮一固连,所述夹板二与齿轮二固连,所述齿轮一和齿轮二啮合以带动夹板一和夹板二开合,假肢手掌部包括连接板一、连接板二、控制夹板一和夹板二夹合的夹取机构和控制夹板一和夹板二放松的连杆机构。所述基于3D打印的带气囊的棘轮止动机械假肢,结构简单、质量轻、成本低,通过机械结构实现柔和的抓取手感。

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RADIATION CURABLE COMPOSITION FOR ADDITIVE MANUFACTURING PROCESSES

NºPublicación: CN110799168A 14/02/2020

Solicitante:

3M\u521B\u65B0\u6709\u9650\u516C\u53F8

WO_2018234898_PA

Resumen de: WO2018234898A1

The invention relates to a radiation curable composition for additive-manufacturing processes, the composition comprising (meth)acrylate component(s) not comprising an urethane moiety having a molecular weight Mw of at least 1,000 as Component A1, photo initiator as Component B, red, yellow or orange dye or combination thereof as Component C, blue dye having a light absorption band in the range of 350 to 420 nm as Component D, and optionally stabilizer as Component E. The invention further relates to a process of producing an elastomeric 3-dim article from the radiation curable composition in an additive-manufacturing process and the obtained elastomeric 3-dim article.

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光交联重组胶原蛋白水凝胶、制备方法及其在3D生物打印中的应用

NºPublicación: CN110790950A 14/02/2020

Solicitante:

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Resumen de: CN110790950A

本发明公开了一种光交联重组胶原蛋白水凝胶、制备方法及其在3D生物打印中的应用。通过将甲基丙烯酸酐加入到重组胶原蛋白的磷酸盐溶液中,充分搅拌反应得到甲基丙基酸酐改性重组胶原蛋白,再将改性重组胶原蛋白溶解于培养基中,加入光引发剂,混合均匀后光反应交联固化制得光交联重组胶原蛋白水凝胶。本发明的重组胶原蛋白水凝胶前驱液置于模具中或作为3D打印墨水,经光反应交联固化制得组织工程支架或3D打印成品,还可在水凝胶前驱液中加入细胞,制备负载细胞的组织工程支架或3D打印成品。本发明的水凝胶理化性能良好、生物相容性好,且质量稳定,成形性良好,可以制备为任意大小和形状,适于大规模工业化生产。

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一种齿科3D打印抗菌材料及其制备方法

NºPublicación: CN110787066A 14/02/2020

Solicitante:

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Resumen de: CN110787066A

本发明公开一种齿科3D打印抗菌材料及其制备方法,该抗菌材料重量百分比组成包括:石墨烯氧化锌纳米棒0.5%‑1.5%、金纳米簇0.5%‑1.5%、大分子低迁移树脂2%‑30%、低迁移活性单体15%‑70%、大分子低迁移紫外光引发剂1%‑4%。本发明通过开发高性能的齿科3D打印抗菌材料,并通过添加金纳米簇、石墨烯氧化锌纳米棒赋予齿科3D打印材料抗菌功能,满足更多临床应用。

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一种生物活性Ti-Ta-Nb合金骨植入体及其成形方法

Nº publicación: CN110791681A 14/02/2020

Solicitante:

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Resumen de: CN110791681A

本发明属于增材制造相关技术领域,其公开了一种生物活性Ti‑Ta‑Nb合金骨植入体及其成形方法,该方法包括以下步骤:(1)提供混合均匀的粉末原材料,所述粉末原材料是原位制备而成的,其原料包括Ta粉、Nb粉及纯Ti粉;在所述粉末原材料中,所述Ta粉的质量百分比为20wt%~30wt%;所述Nb粉的质量百分比为15wt%~40%wt%;(2)以所述粉末原材料为原料、依据使用者缺损部位的三维模型激光选区熔化成形骨植入体,所述骨植入体为多孔结构;其中,所述Ta粉及所述Nb粉在激光束的作用下熔化和扩散对流,且分别催生成TaO薄膜和NbO薄膜。本发明降低了成本,灵活性较好,适用性较强。

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