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Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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种基于三维打印的蚕丝蛋白/明胶支架材料及其制备方法

NºPublicación: CN107041971A 15/08/2017

Resumen de: CN107041971A

本发明提供种基于三维打印的蚕丝蛋白/明胶支架材料及其制备方法,具体方法包括以下步骤:将蚕丝蛋白溶液中加入明胶,形成蚕丝蛋白/明胶复合水凝胶,将蚕丝蛋白/明胶复合水凝胶从三维打印机的针头挤出,按照周期循环的十字网状结构的支架模型打印,同时水凝胶在4℃的接收装置内直接固化成型,最后经冷冻干燥处理,得到基于三维打印的蚕丝蛋白/明胶支架材料。本发明制备方法简单,打印与固化同时进行,生产效率高,不使用化学交联剂和固化剂,绿色环保,且不影响原料的固有特性,制备的支架材料的孔隙率高,孔径大小合适,适合细胞的增殖和分化,支架材料的生物相容性和生物活性好,符合支架的使用要求。



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旋转支承结构和生物打印平台

NºPublicación: CN206403889U 15/08/2017

Resumen de: CN206403889U

本实用新型公开了种旋转支承结构和生物打印平台。旋转支承结构包括旋转轴结构和旋转杆结构,旋转杆结构与旋转轴结构具有组装状态和分解状态,旋转轴结构包括用于输送营养液的第营养液通道,旋转杆结构包括用于输送营养液的第二营养液通道,在组装状态下,第营养液通道与第二营养液通道具有连通状态,在分解状态,第营养液通道与第二营养液通道断开。本实用新型能够降低营养液受到污染的机会。



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种基于多轴联动控制和机器视觉测量的3D打印系统

NºPublicación: CN206403893U 15/08/2017

Resumen de: CN206403893U

本实用新型涉及种基于多轴联动控制和机器视觉测�x91CF;的3D打印系统,包括机架、用以放置人工骨支架的工作台、设置在工作台上方的打印装置、用以输送打印材料的物料输送装置、图像采集相机、用以调整打印装置方位的驱动机构以及控制系统,打印装置、物料输送装置、图像采集装置以及驱动机构均连接至控制系统,工作台为连接在所述机架上的六自由度并联平台,驱动机构为六轴机械臂,打印装置连接在六轴机械臂上。使用时,人工骨支架放置在六自由度并联平台上,通过六轴机械臂控制打印装置的位置,通过六自由度并联平台和六轴机械臂的配合,实现对打印装置的打印喷嘴空间位置的精确控制,实现复杂微细的人工骨表面及多孔结构内部表面的三维图案化打印。



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种3D打印装置

NºPublicación: CN206403894U 15/08/2017

Resumen de: CN206403894U

本实用新型涉及种3D打印装置,包括安装架、电机、气缸、旋转法兰以及多个喷头机构,电机设置在安装架上,旋转法兰连接在电机的输出轴上,多个喷头机构沿周向均匀地布设在旋转法兰上,多个喷头机构以可沿旋转法兰轴向移动的方式连接在安装架上,气缸设置在安装架上且气缸的活塞杆上设有用以驱动喷头机构移动的驱动端,在喷头机构与旋转法兰之间设有用以使喷头机构回位的复位机构。如此,通过电机和旋转法兰实现喷头机构的切换,通过气缸和复位机构实现某喷头机构的伸缩,在打印作业时,某喷头机构伸出安装架进行作业,占用空间小,避免了其它喷头机构对人工骨支架的干扰,本实用新型能够自动进行喷头机构的切换,能够提高生产效率。



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种用于三维生物打印的人脂肪间充质干细胞共混物和三维生物打印人体骨组织的方法

NºPublicación: CN107029294A 11/08/2017

Resumen de: CN107029294A

本发明公开了种用于三维生物打印的人脂肪间充质干细胞共混物,其包含人脂肪间充质干细胞、海藻酸钠、明胶干粉以及作为溶剂的生理盐水的混合物。所述三维生物打印的人脂肪间充质干细胞共混物采用人脂肪间充质干细胞与海藻酸钠‑明胶混合物作为微打印基质;材料具有可塑性并可通过温度和交联剂控制其交联过程,符合细胞共混物三维生物打印的低温打印过程的工艺要求和生物学要求。本发明还公开了种利用本发明所述的用于三维生物打印的人脂肪间充质干细胞共混物三维生物打印人体骨组织的方法,该方法包括传代培养、制备人脂肪间充质干细胞共混物、设计打印物形状、三维打印成型、交联处理等步骤。



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种组织工程支架的3D打印装置及方法

NºPublicación: CN107028681A 11/08/2017

Resumen de: CN107028681A

本发明公开了种组织工程支架的3D打印装置及方法,包括打印模块、喷涂模块、细胞植入模块、打印平台和温控模块;所述打印模块为具有个或多个喷头装置的挤压打印装置,用于挤压打印成型具有三维宏观结构的组织工程支架;所述喷涂模块为具有个或多个喷嘴的喷涂装置,用于成型具有二维宏观结构的组织工程支架;所述细胞植入模块为具有个或多个喷嘴的喷墨打印装置,用于喷出含有种子细胞的微液滴以完成与组织工程支架相对应的细胞和生长因子植入;所述打印平台位于所述打印模块的下方,所述组织工程支架成型于所述打印平台上;所述温控模块用于提供温度可控的打印环境。本发明能实现用多种材料、多种工艺次性成型复杂结构组织工程支架。



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具有多重响应功能的水凝胶及其制备方法和用途

NºPublicación: CN107033372A 11/08/2017

Resumen de: CN107033372A

本发明公开了种具有多重响应功能的水凝胶及其制备方法和用途,该水凝胶的制备方法包括以下步骤:将水凝胶材料、丙烯酰氯、三乙胺加入到溶剂中,冰浴下反应后得到改性水凝胶材料;将双硒二醇、丙烯酰氯、三乙胺加入到溶剂中,冰浴下反应后得到带有碳碳双键的改性双硒;将改性水凝胶材料溶液和改性双硒溶液混合,再加入光聚合引发剂,在20‑40℃、紫外光照射下生成具有多重响应功能的水凝胶。本发明的水凝胶材料对温度、光、氧化还原均有响应性,能通过调节温度、本体浓度、光聚合引发剂浓度、光源实现快速凝胶化,并且易于成型,具有优异的力学性能和生物相容性,其氧化还原响应特性有利于负载不同的药物分子并有效释放。



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种数字化正畸联合种植修复的实现方法

NºPublicación: CN107028668A 11/08/2017

Resumen de: CN107028668A

本发明公开了种数字化正畸联合种植修复的实现方法,方法包括:通过口内扫描仪获取口内初始模型,并获取牙齿待矫正模型;根据牙齿待矫正模型与口内初始模型,及预先设置的矫正幅度值,通过3D打印得到多副牙齿矫治器模型;通过口内扫描仪获取矫正后口内模型,获取待种植/修复牙齿模型,并根据所述待种植/修复牙齿模型获取种植导板模型或贴瓷模型,并将种植导板模型或贴瓷模型进行成型,得到正畸模型。本发明通过数字化设计得到多副牙齿矫治器模型,以及正畸模型,用户通过佩戴牙齿矫治器模型得到种植或修复用空间,且医生通过正畸模型对牙齿进行铁瓷或种植修复,实现数字化牙齿正畸,方便了用户。



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LIQUID EJECTION CONTROL APPARATUS, LIQUID EJECTION SYSTEM, AND CONTROL METHOD

NºPublicación: CN107030788A 11/08/2017

Resumen de: US2017080709A1

A liquid ejection control apparatus, which controls a drive voltage waveform applied to a piezoelectric element so as to control ejection of a pulsed liquid jet, includes a first operation unit that receives input of an index value for setting a flow velocity peak timing of a main jet of the pulsed liquid jet, and a control unit that sets a rising portion of the drive voltage waveform according to the index value so as to control changing of the drive voltage waveform.



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种用于打印机内部净化装置

NºPublicación: CN206391821U 11/08/2017

Resumen de: CN206391821U

本实用新型公开了种用于打印机内部净化装置,包括打印机本体,所述底座上固定连接工作腔和净化腔,所述工作腔顶部设有除尘器和紫外线杀菌灯,所述净化腔顶部设有过滤腔,所述隔板上设有空气净化器,所述空气净化器上设有空气泵,所述空气净化器与工作腔之间通过排风管连接,所述固定板上设有排风扇,所述排风扇与出风口连接,该种用于打印机内部净化装置设计合理,本实用新型,采用的过滤腔能够对外部进入的空气进行过滤,保证外部进入空气的干净,空气净化器可以将空气进行净化再次对空气进行过滤,排风扇能够将工作腔内的污浊空气进行排出,保证了打印机本体内部空气的干净,结构可靠,安全,环保,省力,适合广泛推广和使用。



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种3D打印的个体化风池穴按摩头

NºPublicación: CN206391186U 11/08/2017

Resumen de: CN206391186U

本实用新型提供种3D打印的个体化风池穴按摩头,包括3D打印枕套、风池穴按摩头、弹簧连接杆、振动器、滤网、药物放置盒、红外温度传感器、模数转换器、单片机以及数模转换器,风池穴按摩头通过弹簧连接杆与振动器相连接,该设计实现了头部风池穴的定向按摩,增加了本实用新型的按摩针对性,药物放置盒安装在风池穴按摩头上端面上,滤网设置在药物放置盒上端面上,该设计增加了药物按摩功能,模数转换器通过数据线与红外温度传感器相连接,单片机通过数据线与模数转换器相连接,数模转换器通过数据线与单片机相连接,该设计实现了自动按摩功能,本实用新型结构新颖,工艺合理,理疗效果佳,操作方便,可靠性高。



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DENTAL IMAGER AND METHOD FOR RECORDING PHOTOGRAPHIC IMPRESSIONS

NºPublicación: WO2017136471A1 10/08/2017

Solicitante:
MARTIN MARCO [US]

Resumen de: WO2017136471A1

A dental imager includes an elongated handle with a rotatable head coupled to a distal end thereof and having a central platform with a plurality of arcuate scanning arms pivotally coupled thereto by a hinge. The arcuate scanning arms are of a shape and size for general deployment around a tooth and each include at least one scanner and a roller guide that comfortably rolls along the surface of the tooth or gums to bias the scanners a desired distance from the surface of the tooth, conducive for imaging thereof. In this respect, such a dental imager may be used in a process to scan and record the contours of an intraoral surface, the data of which may be used to create a digital three-dimensional surface impression printable by a 3D printer or the like.



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SOLID PHARMACEUTICAL PREPARATION TEMPLATE CREATING METHOD, COMPUTER-READABLE RECORDING MEDIUM ON WHICH SOLID PHARMACEUTICAL PREPARATION TEMPLATE CREATING PROGRAM IS RECORDED, SOLID PHARMACEUTICAL PREPARATION PRINT INSPECTING METHOD, AND SOLID PHARMACEUTICAL PREPARATION PRINT INSPECTING DEVICE

NºPublicación: WO2017134869A1 10/08/2017

Solicitante:
FREUND CORP [JP]

Resumen de: WO2017134869A1

[Problem] The present invention addresses the problem of reducing the labor involved in creating a template needed to inspect characters or the like printed on the surface of a solid pharmaceutical preparation. [Solution] Provided is a solid pharmaceutical preparation template creating method that is for performing a solid pharmaceutical preparation inspection step for inspecting characters or the like printed on the surface of a solid pharmaceutical preparation by a printing means, the method being characterized by including a print inspection template creating step for creating a print inspection template on the basis of print data, which is scheduled to be used by a printing means, for a solid pharmaceutical preparation to be inspected, prior to the printing of characters or the like using the printing means on the solid pharmaceutical preparation to be inspected.



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PATIENT-SPECIFIC HIP JOINT DEVICES

NºPublicación: US2017224496A1 10/08/2017

Solicitante:
BIOMET MFG LLC [US]

Resumen de: US2017224496A1

An implant for a femoral head of a patient. The implant includes a shell implantable on the femoral head of the patient and correcting a defect of the femoral head. The shell is designed preoperatively to have a patient-specific first surface for articulation with the patient's acetabulum and a patient-specific periphery mateable with a periphery of the defect. The shell caps the defect and the first surface of the shell is continuous to a remaining healthy surface of the femoral head. The defect can be a bone defect, a cartilage defect or a combination thereof.



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Method and Apparatus for Inkjet Printing Absorbent Article Components at Desired Print Resolutions

NºPublicación: US2017225460A1 10/08/2017

Solicitante:
PROCTER & GAMBLE [US]

Resumen de: US2017225460A1

The methods and apparatuses herein relate to inkjet printing a substrate at a desired print resolution. A substrate advances at a first speed under the first printhead and the second printhead such that a desired print resolution exceeds the maximum print resolutions of a first printhead and a second printhead. When the substrate is advancing at the first speed, the first printhead ejects ink onto the advancing substrate at a first firing frequency to create a first printed zone, and the second printhead ejects ink onto the advancing substrate at a second firing frequency to create a second printed zone. In turn, the first printed zone and the second zone together define a printed region having the desired print resolution.



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DIGITAL TO DEFINITIVE ORTHOTIC AND PROSTHETIC DEVICE MANUFACTURING SYSTEM AND METHOD

NºPublicación: WO2017136405A1 10/08/2017

Solicitante:
HANGER INC [US]

Resumen de: WO2017136405A1

Systems and methods for creating custom-fit prosthetic devices, orthotic devices, and related medical devices via three-dimensional printing (3D printing) or additive manufacturing techniques are described. Through the described systems and methods, a residual limb or other body part of a patient is scanned and analyzed to determine measurements and characteristics of the residual limb. The measurements and characteristics of the residual limb are used to design a customized device for the residual limb. The customized device uses multiple different materials. For example, the customized device may use a first material for a frame and a second material for a liner, wherein the first material is more rigid than the second material. The customized device is fabricated using a three-dimensional printer that is capable of printing and bonding multiple different materials at the same time.



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PATIENT-SPECIFIC MANUFACTURING OF POROUS METAL PROSTHESES

NºPublicación: US2017224494A1 10/08/2017

Solicitante:
ZIMMER INC [US]

Resumen de: US2017224494A1

A patient-specific porous metal prosthesis and a method for manufacturing the same are provided. The orthopaedic prosthesis may be metallic to provide adequate strength and stability. Also, the orthopaedic prosthesis may be porous to promote bone ingrowth.



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CUSTOMIZED AORTIC STENT DEVICE AND METHOD OF MAKING THE SAME

NºPublicación: US2017225398A1 10/08/2017

Solicitante:
MAT NV [BE]

Resumen de: US2017225398A1

The application provides customized aortic stent and stent graft devices and methods for the manufacture thereof. The customized aortic stent or stent graft are patient-specific in that they conform to at least part of the ascending aorta, aortic arch and/or thoracic aorta.



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BUILDING METHOD OF AN IMMOBILIZATION DEVICE APPLICABLE TO ONE BODY SEGMENT OF A PATIENT

NºPublicación: EP3202377A1 09/08/2017

Solicitante:
RANALDO DAVIDE [IT]
LAZZARO JACOPO [IT]

Resumen de: EP3202377A1

A building method of an immobilization device ( 1 ) applicable to at least one body segment of a patient to at least partially immobilize it. Said method comprising the following steps:detecting the volumetric dimensions of the patient's body segment; setting the shaping of said immobilization device ( 1 ); printing said immobilization device ( 1 ) using a 3D printer, said 3D printer comprising at least one pair of nozzles for the emission of materials having different physical characteristics so as to vary, area by area, the physical characteristics of said device immobilization ( 1 ).



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种抗凝血药物的制备方法

NºPublicación: CN107019676A 08/08/2017

Resumen de: CN107019676A

本发明提供了种华法林抗凝血药物的制备方法,是将主料及辅料加入3D打印机中,通过计算机进行3D建模,然后将3D建模数据传输至3D打印机,利用自带的软件分层切片处理,并形成相应的代码,上述的主料和辅料通过热熔挤出的方式,从喷嘴挤出,3D打印机的打印头在平面上进行X,Y轴的运动,进行单层打印,随着打印机逐层累积并相互粘结,完成所述的华法林抗凝血药物的制备。



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种基于光固化3D打印技术个体化定制型的二氧化锆多孔生物骨修复支架及其制备方法

NºPublicación: CN107007888A 04/08/2017

Resumen de: CN107007888A

本发明涉及生物陶瓷支架材料的制备方法。种基于光固化3D打印技术个体化定制型的二氧化锆多孔生物骨修复支架的制备方法,该方法包括以下的步骤:(1)利用CT二、三维成像技术建立骨骼未受损时的健康状态图,再结合等待植入的缺损骨骼状态图,分离出需植入的骨骼形态图;(2)利用专用数据软件把CT数据转化为3D打印数据;(3)利用光固化3D打印技术个体化制备二氧化锆多孔生物骨修复支架。该方法的骨修复生物陶瓷材料符合个体化治疗原则,制造工艺时间短,效率高,所制得的材料孔隙率较为精准,误差小,抗压、抗弯强度大,生物相容性好。



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可用于药物加载和释放的可注射型自愈合凝胶及其制备方法和应用

NºPublicación: CN107007881A 04/08/2017

Resumen de: CN107007881A

本发明公开了种可用于药物加载和释放的可注射型自愈合凝胶及其制备方法和应用。本发明使用带表面电荷的高分子微凝胶颗粒,通过颗粒间的静电相互作用自组装得到胶体凝胶。由于微凝胶之间的静电作用是物理交联且具有可逆性,本发明的胶体凝胶具有良好的可注射性和自愈合能力,在注射和固化过程无需引入化学交联反应,不同于化学高分子,也没有引入小分子交联剂,生物相容性好,可降解吸收,无毒副作用,安全性好,使其在生物医学领域的广泛应用成为可能。



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种微小肺癌的早期诊断装置

NºPublicación: CN107007295A 04/08/2017

Resumen de: CN107007295A

种微小肺癌的早期诊断装置,包括CT机、计算机、3D打印机,所述CT机具有配套的移动床,CT机右侧安装计算机,CT机通过导线和计算机相连,CT机自带的图像输出功能输出的图像传输到计算机上,使图像在计算机上呈现,计算机右侧安装3D打印机,3D打印机通过导线和计算机相连,计算机将图像信息传递给3D打印机,CT机自带的图像输出功能输出的图像经过计算机内安装的VG studio max软件转换层gcode格式的图像;本发明的优点是:能打印三维立体图像。



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LIQUID EJECTION CONTROL APPARATUS, LIQUID EJECTION SYSTEM, AND CONTROL METHOD

NºPublicación: CN107009431A 04/08/2017

Resumen de: US2017080710A1

A liquid ejection control apparatus, which controls a drive voltage waveform applied to a piezoelectric element so as to control ejection of a pulsed liquid jet, includes a first operation unit that receives input of an index value for setting a position of an inflection point in a rising portion of the drive voltage waveform, and a control unit that sets the position of the inflection point in the rising portion of the drive voltage waveform according to the index value so as to control changing of the drive voltage waveform.



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种基于鼻腔3D打印脱模充气囊袋制备及其应用

Nº publicación: CN107007315A 04/08/2017

Resumen de: CN107007315A

本发明采用鼻腔全息照相技术采样及大众化典型归类优化,获得几种典型普适全吻合型的鼻腔信息数据,并依据此数据传输给3D打印设备,制备鼻腔底模,再采用乳胶浸渍法制备无缝鼻腔气囊袋,该气囊充气后可以很好地与鼻腔形状进行吻合,对于不规则的鼻腔,借由伸缩性很好的乳胶材料得到填充,从而达到整个鼻腔全吻合的目的。可充气全吻合型鼻腔气囊,配合止血纱布,包括可溶凝胶型或防粘连纱布涂层或无纺布,用于鼻腔手术或损伤性流血止血、鼻腔矫正定形等方面的填充作用的应用。具有对鼻腔全吻合、囊体无边封的特点,即使有个体差异和特殊形状也可通过囊袋的伸缩性达到全吻合。


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