CORONAVIRUS: DIAGNÓSTICO Y TERAPIA EN HUMANOS

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Resultados 161 resultados LastUpdate Última actualización 20/01/2021 [20:13:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 120 días/Published applications in the last 120 days



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Method and composition for the reduction of viral replication, duration and spread of the COVID-19 and the Flu

NºPublicación: US2021008105A1 14/01/2021

Solicitante:

MARTIN ALAIN [US]
CELLULAR SCIENCES INC

Resumen de: US2021008105A1

A method for stimulating the synthesis of nasal nitric oxide and nasal and lung surfactants to inhibit the docking and adhesion of viruses to cellular receptors, including ACE2, to reduce viral replication, duration, spread and severity of infections, and also to inhibit lung fibrosis, increase the synthesis of serotonin to reduce coughing and mouth breathing, reduce the cytokine storm produced by LI-6 caused by viruses such as COVID-19 and flu in patients susceptible to these infections, including patients with hypoxemia, asthma, chronic obstructive pulmonary disease, cystic fibrosis, diabetics, interstitial lung disease, pulmonary fibrosis, allergic rhinitis, sinusitis, smokers, sleep apnea and lung cancer, which includes: contacting mammalian cells with a therapeutically effective amount of a composition, said composition including the following constituents: sodium pyruvate; a phosphate; a salt of calcium; and a salt of magnesium.

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Systems and Methods for Real-Time Health Certification Using Point-of-Care Data

NºPublicación: US2021012869A1 14/01/2021

Solicitante:

BIOSAFETY DIAGNOSTICS INC [US]

Resumen de: US2021012869A1

A health pass system for COVID-19 is provided. The system includes a database including information on a plurality of individuals. The database is configured to receive point-of-care data relating to the plurality of individuals, the point-of-care data including at least one medical test result for COVID-19 antibodies for at least one of the plurality of individuals. The system includes a processing device configured to analyze the point-of-care data and generate a report. The system includes means for transmitting the report to a mobile electronic device of at least one of the plurality of individuals. The system includes means for displaying the report with a user interface of the mobile electronic device in the form of a real-time health certification.

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NOVEL GALACTOSIDE INHIBITOR OF GALECTINS

NºPublicación: WO2021004940A1 14/01/2021

Solicitante:

GALECTO BIOTECH AB [DK]

Resumen de: WO2021004940A1

The present invention relates to a D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of inflammation; Inflammation induced thrombosis; Atopic dermatitis; Acute coronary syndrome; fibrosis, such as pulmonary fibrosis, liver fibrosis, kidney fibrosis, ophthalmological fibrosis and fibrosis of the skin and heart; local fibrosis such as Dupuytren's disease and Peyronie's disease; fibrotic complications of other therapies such as coronary stents, bile duct stents, cerebral artery stents, ureter stents; scleroderma; scarring; keloid formation; covid-19; acute lung injury; ARDS; viral pneumonitis, aberrant scar formation; surgical adhesions; septic shock; cancer, such as colorectal cancer, other gastrointestinal carcinomas such as pancreatic cancer, gastric cancer, biliary tract cancer, lung cancers, mesothelioma, female cancers like breast cancer, ovarian cancer, uterine cancer, cancer of the cervix uteri, cancer of the salpingx, cerebral cancers such as medulloblastomao, glioma, meningioma, sarcomas of the bones and muscles and other sarcomas, leukemias and lymphomas, such as T-cell lymphomas; transplant rejection; metastasising cancers; ageing; Dementia; Alzheimers; TGFbeta driven bone disease such as osteogenesis imperfecta; Pulmonary hypertension; autoimmune diseases, such as psoriasis, rheumatoid arthritis, Rheumatoid lung; Crohn's disease, ulc

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PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS

NºPublicación: US2021008150A1 14/01/2021

Solicitante:

UNIV EMORY [US]

Resumen de: US2021008150A1

Compounds, compositions and methods for preventing, treating or curing a coronavirus, picornavirus, and/or hepeviridae virus infection in human subjects or other animal hosts. Specific viruses that can be treated include enteroviruses. In one embodiment, the compounds can be used to treat an infection with a severe acute respiratory syndrome virus, such as human coronavirus 229E, SARS, MERS, SARS-CoV-1 (OC43), and SARS-CoV-2. In another embodiment, the methods are used to treat a patient co-infected with two or more of these viruses, or a combination of one or more of these viruses and norovirus.

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COVID-19 symptoms alert machine (CSAM) scanners

NºPublicación: US10888283B1 12/01/2021

Solicitante:

BENJAUTHRIT BOONSIENG [US]
BENJAUTHRIT SORAPOD B [US]
BENJAUTHRIT VATCHAREE L [US]
BENJAUTHRIT KAMOLCHANOK J [US]

Resumen de: US10888283B1

A COVID-19 Symptoms Alert Machine (CSAM) scanner, or apparatus, is described herein. This apparatus employs Artificial Intelligent (AI) technology in combination with the latest mobile device technology (viz. smart phone/smart watch) to quickly help track down people who have COVID-19 symptoms anywhere and anytime, isolate them, and professionally handle them, not allowing SARS-CoV-2 virus to spread. CSAM automatically measures body temperature and assesses lung conditions such as pulmonary fibrosis and B-lines (for asymptomatic people), and other current health vital information (CHVI), furnished by the participant, such as fever, sore throat, headache, and body ache to generate an alert signal when COVID-19 symptoms are found significant and to send it out to a COVID-19 control center. The alerted participant is then immediately required to go to the COVID-19 control center or be picked up by a special COVID-19 emergency vehicle for isolation and further evaluation and testing. If the testing turns out to be COVID-19 positive, the participant will be quarantined and treated appropriately according to COVID-19 protocol until he/she is tested COVID-19 negative. In the meantime, people who have been in close physical contact with this participant will be alerted and requested to be immediately checked for COVID-19 symptoms. If anyone is found to have COVID-19 symptoms, then he/she must go through the same protocol. The process is repeated until all people in the cluster are te

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BiChip V1 Implantable NFC and Smart Thermometer

NºPublicación: DK202001441A1 08/01/2021

Solicitante:

BEZH DENMARK APS [DK]

Resumen de: DK202001441A1

BiChip V1 (version 1) implantable passive RFID-NFC transponder chip with a smart thermometer for health monitoring through in-vivo body temperature monitoring, that can store identification and access control data like opening house and car doors, or checking in at work places, and various forms of contactless payment which require authentication processes. Use of BiChip V1 for Health Monitoring and Health Status Verification during COVID-19 and other pandemics The smart thermometer in BiChip V1 is able to accurately monitor temperature ranges of between 30°C to 45°C, and records fluctuations in body temperature, thereby able to generate data that can create a ‘Body Temperature Profile’ for the user. This body temperature profile can serve as a baseline for accessing the user's health, a feature which can be crucial during pandemics such as COVID-19 whereby having a record of recent temperature fluctuations of a user, can be used to speed up testing for COVID-19, even more among asymptomatic people. As COVID-19 vaccines are getting approved around the world, the body temperature profile from BiChip V1 can be used to verify the infection status of a user who has not yet received a vaccine, allowing the user to continue with their daily lives where restrictions would have otherwise been imposed for quarantine purposes due to uncertainty about their COVID-19 status. BiChip V1 as an Identity Verifier The Body Temperature Profile generated from the smart thermometer’s data

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IMMUNOBIOLOGICAL AGENT FOR INDUCING SPECIFIC IMMUNITY AGAINST SEVERE ACUTE RESPIRATORY SYNDROME VIRUS SARS-COV-2

NºPublicación: WO2021002776A1 07/01/2021

Solicitante:

FEDERAL STATE BUDGETARY INSTITUTION NATIONAL RES CENTRE FOR EPIDEMIOLOGY AND MICROBIOLOGY NAMED AFTE [RU]

RU_2720614_C1

Resumen de: WO2021002776A1

The invention relates to biotechnology, immunology and virology and, in particular, to an immunobiological agent for the prevention of diseases caused by severe acute respiratory syndrome virus SARS-CoV-2. Also, a method of inducing specific immunity to the SARS-CoV-2 virus is disclosed, comprising the administration to mammals of one or more immunobiological agents for the prevention of diseases caused by severe acute respiratory syndrome virus SARS-CoV-2. The invention facilitates an effective induction of the immune response to the SARS-CoV-2 virus.

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THERAPEUTIC USES OF OXIDISING HYPOTONIC ACID SOLUTIONS

NºPublicación: WO2021001789A1 07/01/2021

Solicitante:

APPLIED PHARMA RES [CH]

Resumen de: WO2021001789A1

Methods for treating or preventing ulcers caused by Epidermolysis Bullosa ("EB"), EGFR inhibitor-induced skin toxicities, lesions caused by Hailey-Hailey Disease ("HHD"), Buruli Ulcers, and SARS-CoV-2 infections, by topically applying a hypotonic, acid oxidizing solution containing hypochlorous acid (HClO) to the affected area.

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NOVEL GALACTOSIDE INHIBITOR OF GALECTINS

NºPublicación: WO2021001538A1 07/01/2021

Solicitante:

GALECTO BIOTECH AB [DK]

Resumen de: WO2021001538A1

The present invention relates to a D-galactopyranose compound of formula (1) wherein the pyranose ring is α-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors for use in treatment of inflammation; Inflammation induced thrombosis; Atopic dermatitis; Acute coronary syndrome; fibrosis, such as pulmonary fibrosis, liver fibrosis, kidney fibrosis, ophthalmological fibrosis and fibrosis of the skin and heart; local fibrosis such as Dupuytren's disease and Peyronie's disease; fibrotic complications of other therapies such as coronary stents, bile duct stents, cerebral artery stents, ureter stents; scleroderma; scarring; keloid formation; covid-19; acute lung injury; ARDS; viral pneumonitis, aberrant scar formation; surgical adhesions; septic shock; cancer, such as colorectal cancer, other gastrointestinal carcinomas such as pancreatic cancer, gastric cancer, biliary tract cancer, lung cancers, mesothelioma, female cancers like breast cancer, ovarian cancer, uterine cancer, cancer of the cervix uteri, cancer of the salpingx, cerebral cancers such as medulloblastomao, glioma, meningioma, sarcomas of the bones and muscles and other sarcomas, leukemias and lymphomas, such as T-cell lymphomas; transplant rejection; metastasising cancers; ageing; Dementia; Alzheimers; TGFbeta driven bone disease such as osteogenesis imperfecta; Pulmonary hypertension; autoimmune diseases, such as psoriasis, rheumatoid arthritis, Rheumatoid lung; Crohn's disease, ulcerative col

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Personal Protective Face Shield for Preventing Biohazardous, Infectious or Pathological Aerosol Exposure (COVID-19)

NºPublicación: US2021001157A1 07/01/2021

Solicitante:

RASHAUD TARIQUE JIBRIL [US]
GOUDEAUX XAVIER JIBRIL [US]

Resumen de: US2021001157A1

This novel face shield/window is designed to provide all the protective qualities of traditional OSHA approved PPE face shields. Most critically, however, it also facilitates the creation of a protective Dynamic Ingress Barrier to prevent fine particles and bioaerosols from crossing the face shield plane and transport them away from the often breached and problematic periphery of mask/respirator protective zones. Integral to this process, the novel design enhances a particle's flocculant properties by disrupting the structural integrity of the corona virus electrostatic double layer, and reducing its electrokinetic potential before accelerating it into the airspace. Increasing its ability to flocculate with active viral aerosols, and subsequently settle out of the airspace for cleaning, or captive via a filter.

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HANDHELD SENSOR FOR RAPID, SENSITIVE DETECTION AND QUANTIFICATION OF SARS-CoV-2 FROM SALIVA

NºPublicación: US2021003528A1 07/01/2021

Solicitante:

UNIV FLORIDA [US]

Resumen de: US2021003528A1

Various examples are provided for disposable medical sensors that can be used for detection of SARS-CoV-2 antigen, cardiac troponin I, or other biosensing applications. In one example, a medical sensing system includes single-use disposable test strip comprising a functionalized sensing area configured to detect SARS-CoV-2 antigen and a portable sensing and readout device including pulse generation circuitry that can generate synchronized gate and drain pulses for detection and quantification of SARS-CoV-2 antigen in biological samples. In another example, a method includes providing a saliva sample to a functionalized sensing area configured to detect SARS-CoV-2 antigen, generating synchronized gate and drain pulses for a transistor, the gate pulse provided via electrodes of the functionalized sensing area, and sensing an output of the transistor that is a function of a concentration of SARS-CoV-2 antigen in the sample.

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VACCINES FORMED BY VIRUS AND ANTIGEN CONJUGATION

NºPublicación: US2021000942A1 07/01/2021

Solicitante:

KENTUCKY BIOPROCESSING INC [US]

Resumen de: US2021000942A1

Disclosed herein are methods of forming compounds and exemplary compounds in the nature of a conjugated compound, which in some embodiments comprises an antigen and virus particle mixed in a conjugation reaction to form a conjugate mixture, such that the conditions and steps of forming these products allow for use of the conjugate mixture as a vaccine, including but not limited to use as a vaccine against various pathogens including for treatment of diseases caused by novel coronaviruses (including SARS-COV 2).

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NUCLEIC ACID SEQUENCE EXPRESSING SARS-COV-2 VIRUS ANTIGEN PEPTIDE AND USE THEREOF

NºPublicación: WO2021000969A2 07/01/2021

Solicitante:

GUANGZHOU N BIOMED LTD [CN]

Resumen de: WO2021000969A2

Disclosed are a nucleic acid sequence expressing SARS-CoV-2 virus antigen peptide and a use thereof. The nucleic acid sequence is Seq ID No. 1, Seq ID No. 2, or a sequence having at least 90% homology. The nucleic acid sequences in some embodiments of the present invention can be effectively expressed in human cells, produce corresponding polypeptides, induce the production of corresponding immunological protective response, and has the potential to be developed into a SARS-CoV-2 vaccine.

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ADENOVIRUS CARRIER VACCINE USED FOR PREVENTING SARS-COV-2 INFECTION

NºPublicación: WO2021000968A2 07/01/2021

Solicitante:

GUANGZHOU N BIOMED LTD [CN]

Resumen de: WO2021000968A2

Disclosed is an adenovirus carrier vaccine used for preventing SARS-CoV-2 infection. Said vaccine comprises a nucleotide sequence represented in Seq ID No. 1. In some embodiments of the present invention, the S protein nucleotide sequence in the vaccine is easy to express in human cells, can induce more production of S proteins, and has the potential to be a recombinant virus vaccine for the prevention of SARS-Cov-2 infection. Some embodiments of the present invention has good safety.

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SYSTEM AND METHOD FOR DETECTION AND SORTING OF CELLS

NºPublicación: US2021001339A1 07/01/2021

Solicitante:

MICROSENSOR LABS LLC [US]

Resumen de: US2021001339A1

A system and method for detection of cells and sorting of cells are disclosed. Target cells, such as circulating tumor cells (CTCs) or antigen-specific antibody producing circulating memory B cells from COVID-19 patients, may be of interest. Magnetic beads may be bound to the target cells. After which, the bead-bound target cells may be identified using an applied magnetic field. In one example, magnetic sensors may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. In another example, an optical sensor may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. Further, separate from identification of the target cells, the bead-bound target cells may be sorted using an applied magnetic field. In this way, a magnetic field may be used for target cell identification and target cell sorting in order to detect and collect target cells of interest at the single-cell resolution.

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Antiviral and virucidal nasal spray compositions and related treatment methods

NºPublicación: US10874650B1 29/12/2020

Solicitante:

FERRER MEDICAL INNOVATIONS LLC [US]

Resumen de: US10874650B1

Compositions for treatment or prevention of viral infections, such as influenza A and B, coronaviruses, including but not limited to COVID-19, and rhinoviruses, along with related treatment methods. Certain compositions according to preferred embodiments of the invention may comprise chlorpheniramine, xylitol, and other inactive ingredients, such as aloe vera and/or grapefruit seed extract.

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Highly active compounds against COVID-19

NºPublicación: US10874687B1 29/12/2020

Solicitante:

ATEA PHARMACEUTICALS INC [US]

Resumen de: US10874687B1

The present invention is the use of a small group of purine nucleotide phosphoramidate disclosed herein or a pharmaceutically acceptable salt thereof in an effective amount for the treatment or prevention of the novel 2019 coronavirus disease (COVID-19) in a host, for example a human, in need thereof.

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3D OBJECT CONTAINING CBD AND PRINTING OPERATING SYSTEM THEREFOR

NºPublicación: WO2020256371A2 24/12/2020

Solicitante:

BIO MEDICAL 3D PRINTING CO LTD [KR]

Resumen de: WO2020256371A2

The present invention relates to a printing operating system for a 3D object containing CBD, the 3D printing operating system of the present invention providing a printing operating method for a 3D object, whereby CBD-containing food, such as coffee, juice, syrup, sauce, ice cream, yogurt, chocolate, cookies, candy, etc., or CBD-containing products using a fluid, such as candles (scented candles), soap, cosmetics, oils, etc., are provided by being printed into various and distinctive shapes catering to consumer preferences, while quantitative control and verification are enabled so that the 3D object contains an amount of CBD which is legally allowed in each country. The 3D printing operating system (500) of the present invention implements a teleportation concept-based drug delivery method enabling contactless remote diagnosis and, at the same time, delivery of drugs such as CBD in an emergency situation such as the prevalence of coronaviruses (such as COVID-19) or various infectious diseases, and thus may become a useful CBD usage/delivery method to many users experiencing difficulties relating to tic disorders, sleep disorders, epilepsy in children and the alleviation of pain caused by various diseases.

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TREATMENT OF ACUTE MEDICAL CONDITIONS

NºPublicación: WO2020254793A1 24/12/2020

Solicitante:

GALVANI BIOELECTRONICS LTD [GB]

Resumen de: WO2020254793A1

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

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AN INTEGRATED SECURE COVIDE-19 CONTACT TRACING FRAMEWORK USING IOT PLATFORM WITH BLOCKCHAIN

NºPublicación: AU2020102965A4 24/12/2020

Solicitante:

GARG LALIT
CHUKWU EMEKA
NASSER NIDAL
CHAKRABORTY CHINMAY
GARG GAURAV

Resumen de: AU2020102965A4

AN INTEGRATED SECURE COVIDE-19 CONTACT TRACING FRAMEWORK USING IOT PLATFORM WITH BLOCKCHAIN Abstract The contact tracing process is inevitable approach which obverse required in the pandemic situation (COVID-19) to protect our human mankind. Unfortunately, health care centre from all over the world do not have unique feature and pattern to trace out the identify of infection carrying person. Nowadays, online digital marketing enters into all commercial business trades includes Gasari Bazaar, Education, Telemedicine, etc where it requires new model for data aggregation and sharing present to continue business transaction, thus, retain economic standard of the society. For smooth functioning of above-mentioned sectors, health care department should provide essential information about isolation zone, affected person area and continuous updating of infection count. Therefore, it is required the effective and user-friendly model of contact tracing approach which accompany patient privacy and health information security. Thereby, an integrated secure covide 19 contact tracing framework using IoT platform with blockchain technology is implemented to provide secured storage of patient's information and minimize the cost of scaling to existing contact tracing strategies. This model measures moving infection person count and protect the test result of voluntarily participation. RFID transceiver (proof-of-concept) involves tracking the moving test samples and record of test samples stor

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MICROPARTICLE COMPOSITIONS FOR TREATMENT OF INFECTION OR DISEASE, METHODS OF MAKING THE SAME, AND METHODS OF TREATING SUBJECTS WITH MICROPARTICLE COMPOSITIONS

NºPublicación: US2020397711A1 24/12/2020

Solicitante:

LEE GREGORY BRIAN [US]

Resumen de: US2020397711A1

Provided are microparticle compositions, methods of making the compositions, and methods of treating a subject with the present microparticle compositions by administering an effective amount of the microparticle composition for treating an infection or disease, to a subject in need thereof. The present microparticle compositions may include microparticles of essential oils, herbs, and/or supplements. By way of non-limiting example, the microparticle compositions may be particularly effective in the treatment of a Lyme tick borne illness related infection or disease, or a coronavirus, such as COVID-19. Also included are kits that include one or more of the present microparticle compositions and/or one or more components of the present compositions, and optionally one or more components, such as a device to aid in the delivery of the composition and/or instructions for administration.

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COMPENSATED SPLIT VENTILATOR CIRCUIT

NºPublicación: US2020398015A1 24/12/2020

Solicitante:

KEYSIGHT TECHNOLOGIES INC [US]

Resumen de: US2020398015A1

In response to the global shortages of medical ventilator due to emergence of COVID-19 pandemic, the expansion of ventilator availability can be realized by having a Compensated Split Ventilator Circuit fitted into a mechanical ventilator. Hence, a single ventilator may be shared by two patients simultaneously with moderately different lung resistances and compliances. The Compensated Split Ventilator Circuit enables for differential gas volume between two patients by adjusting the valves in the inspiratory and expiratory circuits to control the optimized amount of gas flow to each patient individually. Embodiments of the present invention may be implemented using off-the-shelf medical-grade components to ensure product durability and patient safety.

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Systems and Methods For Internet-Of-Things (IOT) Robotic Sterilization Device

NºPublicación: US2020397936A1 24/12/2020

Solicitante:

ATOM INC [US]

Resumen de: US2020397936A1

An internet-of-things (IOT) robotic sterilization system that operates autonomously for use in the prevention of diseases, e.g., Coronavirus Disease 2019 (COVID-19), caused by pathogens such as coronavirus SARS-CoV-2 and other pathogens present within an interior space is described. A robotic sterilization device is communicatively coupled to the IOT base module via an IOT network, and includes a misting or fogging system fluidically coupled to a liquid reservoir, a sensor module including plurality of sensors, a controller, and a locomotion system. The robotic sterilization device navigates a path within the interior space while creating a disinfecting mist with the misting system, and may coordinate with other IOT-connected devices, such as the HVAC system, UV Vent sterilizers, scent dispensing appliances, and others to more efficaciously sanitize the interior space to protect humans by eliminating pathogens.

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TREATMENT OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS

NºPublicación: US2020397871A1 24/12/2020

Solicitante:

ANSUN BIOPHARMA INC [US]

US_2019262432_A1

Resumen de: US2020397871A1

The present disclosure provides novel compositions and methods for treating an infection by MERS-CoV. In particular, the present disclosure provides methods that entail administering agents having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by MERS-CoV.

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TREATMENT OF ACUTE MEDICAL CONDITIONS BY STIMULATING THE NEURAL ACTIVITY OF A NERVE SUPPLYING THE SPLEEN

Nº publicación: WO2020254797A1 24/12/2020

Solicitante:

GALVANI BIOELECTRONICS LTD [GB]

Resumen de: WO2020254797A1

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

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