CORONAVIRUS: DIAGNÓSTICO Y TERAPIA EN HUMANOS

VolverVolver

Resultados 532 resultados LastUpdate Última actualización 19/01/2022 [11:53:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 60 días/Published applications in the last 60 days



Página1 de 22 nextPage   por página


DISEASE DIAGNOSIS USING SPECTROSCOPY AND MACHINE LEARNING

NºPublicación: US2022011224A1 13/01/2022

Solicitante:

MASSACHUSETTS INST TECHNOLOGY [US]
MOHAMMED VI POLYTECHNIC UNIV [MA]
LABORATOIRE ANOUAL [MA]
MASSACHUSETTS INTITUTE OF TECH [US]

US_2022011219_A1

Resumen de: US2022011224A1

Aspects of the present application relate to techniques of diagnosing whether a pathogen (e.g., SARS-CoV-2) is present in a subject using infrared (IR) spectroscopy and machine learning techniques. The techniques use spectral data obtained from performing IR spectroscopy on a biological sample (e.g., saliva or nasal sample, or genetic material extracted therefrom) to generate a set of feature values. The feature values are provided as input to a machine learning model to obtain output indicating whether the pathogen is present in the biological sample. The output of the machine learning model may be used to determine a diagnosis result for a subject.

traducir

DISEASE DIAGNOSIS USING SPECTROSCOPY AND MACHINE LEARNING

NºPublicación: US2022011219A1 13/01/2022

Solicitante:

MASSACHUSETTS INST TECHNOLOGY [US]
MOHAMMED VI POLYTECHNIC UNIV [MA]
LABORATOIRE ANOUAL [MA]

US_2022011224_A1

Resumen de: US2022011219A1

Aspects of the present application relate to techniques of diagnosing whether a pathogen (e.g., SARS-CoV-2) is present in a subject using infrared (IR) spectroscopy and machine learning techniques. The techniques use spectral data obtained from performing IR spectroscopy on a biological sample (e.g., saliva or nasal sample, or genetic material extracted therefrom) to generate a set of feature values. The feature values are provided as input to a machine learning model to obtain output indicating whether the pathogen is present in the biological sample. The output of the machine learning model may be used to determine a diagnosis result for a subject.

traducir

METHODS OF TREATING COVID-19 PATHOGENESIS

NºPublicación: US2022008380A1 13/01/2022

Solicitante:

UT BATTELLE LLC [US]

Resumen de: US2022008380A1

This disclosure provides methods for treating a SARS-CoV-2 infection in a subject comprising administering to the subject an effective amount of an inhibitor of COVID-induced RAS imbalance, that downregulates, for example, the Bradykinin system, the Renin-Angiotensin system, the hyaluronan synthesis pathway, or the fibrinogenesis pathway.

traducir

Pressure Differential-, Ultrasound-, and Magnetic-Based Methods for Treating Viral Infections and other Pathogenic Diseases, Sterilizing Medical Equipment, and Enhancing Fatty Tissue Reduction

NºPublicación: US2022008276A1 13/01/2022

Solicitante:

CURIEL GABRIEL [MX]
WAGGETT GORDON G [US]
KLUG JOHN R [US]

Resumen de: US2022008276A1

The present disclosure is directed to methods of treating subject patients (such as humans, animals, plants) suffering from a pathogenic disease such as COVID-19 in humans, via the administration of pressure changes in the patient sufficient to cause a pressure differential to be created between the inside and outside of the outer membrane or envelope of the pathogen thereby destroying or disabling the pathogen. In one embodiment, a hyperbaric chamber is used to administer pressure increases and/or pressure decreases to create such pressure differential. The hyperbaric chamber could comprise a single user or multi-user unit, a pressurized body suit, or the pressurizable fuselage of an aircraft. In another embodiment, patients are placed in an aircraft, and the cabin pressure, while on the ground, or in flight, is adjusted upwardly or downwardly to create such pressure differential. The pressure differential methods can also include the use of external gases to enter the patient's body and/or lungs to facilitate disruption of the pathogen outer membrane as well as application of variations in temperature and/or humidity. A mobile treatment unit is also disclosed. Also disclosed are methods of using ultrasonic cavitation or MRI (or other sonic or magnetic field forces sufficient to disrupt the functionality of the pathogen), or a combination of ultrasound and MRI on the exterior of a patient in a desired anatomical region of the patient to assist with the destruction or disabli

traducir

Safety helmet with lift-able touch-less visor for social distancing

NºPublicación: US2022007775A1 13/01/2022

Solicitante:

MATULIS VISVYDAS [LT]

Resumen de: US2022007775A1

The present invention is a safety helmet with two rounded safety visors. The back visor is fixed, the front visor—movable up and down. This new safety helmet with lift-able front visor and fixed back visor enables people to socialize, while reducing risk of getting infected by Covid-19 virus or other airborne viruses. The lifting of the front visor could be achieved with a help of a handle or other means.

traducir

TREATMENT OF SEVERE ACUTE RESPIRATORY SYNDROME-RELATED CORONAVIRUS INFECTION WITH KLOTHO

NºPublicación: US2022008519A1 13/01/2022

Solicitante:

COSTA RICAN SOCIAL SECURITY FUND / CAJA COSTARRICENSE DE SEGURO SOCIAL CCSS [CR]

Resumen de: US2022008519A1

Methods and compositions for treating a severe acute respiratory syndrome-related coronavirus (SARS-CoV) infection in a subject in need are provided. In some aspects, a therapeutically effective amount of a Klotho polypeptide and/or a Klotho polynucleotide encoding a Klotho polypeptide is administered to the subject. In some other aspects, the subject is treated with a first therapy when the subject has diminished Klotho activity, and with a second therapy when the subject does not have diminished Klotho activity. Diminished Klotho activity is determined by comparing the amount of Klotho protein in a blood sample from the subject to a predetermined threshold. In particular, methods and compositions for treating SARS-CoV-2 infection are provided.

traducir

Frequency Selective Viral Inactivation through Bond Breaking

NºPublicación: US2022008572A1 13/01/2022

Solicitante:

GRAHAM JR JAMES ARTHUR [US]
HEIDARI BATENI GHOBAD [US]
BRADEN STANTON C [US]
GREGERSEN CRAIG MARTIN [US]

US_11052166_B1

Resumen de: US2022008572A1

An apparatus is provided for delivering IR and/or UV radiation, to an area or a surface in which virions, such as SARS-CoV-2 (the virus that causes the disease, COVID-19), may exist, wherein the IR radiation is intended to degrade the viral envelope of the virions and wherein the UV radiation is intended to break specific molecular bonds in order to degrade the RNA of the virion contained within a viral envelope.

traducir

TMA-PHT Complex (Olive Triterpenic and Polyphenolic Compounds) and Their Combinations, As A Group of Phytochemical Drug Compositions and/or Pharmaceutical Products for The Treatment of COVID-19 and Other Human and Animal Diseases and Conditions

NºPublicación: US2022008438A1 13/01/2022

Solicitante:

SARMENTERO ALBERTO [US]
PRADOS OSUNA JOSE [ES]

Resumen de: US2022008438A1

TMA-PHT complex (olive triterpenic and polyphenolic compounds) and their combinations are used for preventing, alleviating, treating, or curing abnormal and/or pathological conditions of the living body, by such means as: (a) protecting the good health conditions of a living body by attracting, disabling, inhibiting, killing, modifying, repelling and/or retarding a virus or micro-organism in the case of preventing an infection (b) destroying a virus or a parasitic organism; (c) limiting the affecting of the disease by altering the physiology of the virus or parasite. In accordance with various embodiments, the present subject matter pertains to pharmaceutical drug compositions targeting various therapeutic objectives and their methods for preventing or treating Covid19 and/or other diseases and certain health conditions including the ones associated with inflammation and/or oxidative stress.

traducir

MERS-CoV VACCINE COMPOSITION

NºPublicación: US2022008530A1 13/01/2022

Solicitante:

UNIV KING ABDULAZIZ [SA]

US_11219685_B1

Resumen de: US2022008530A1

An immunogenic CD40-targeted trimeric MERS-CoV S1 fusion polypeptide as well as a corresponding polynucleotide encoding it and its use for safely inducing immune responses directed against MERS-CoV without inducing vaccine associated respiratory pathologies associated with non-targeted vaccines.

traducir

COVID-19 DISINFECTANT HAND-HELD PORTABLE MISTING SPRAYER SYSTEM METHOD AND DEVICES

NºPublicación: US2022008585A1 13/01/2022

Solicitante:

YAMASHIRO STEVEN B [US]
ALABATA ENRIQUE PRENDA [US]

Resumen de: US2022008585A1

The embodiments disclose a method including providing a hand-held portable misting sprayer for applying HOCL to surfaces of objects for destroying airborne and surface contacted COVID-19 SARS-CoV-2 virus and other viruses, coupling a portable rechargeable battery to the hand-held portable misting sprayer for supplying power to operate elements of the hand-held portable misting sprayer, coupling a reservoir to the hand-held portable misting sprayer for containing a volume of HOCL for processing in spraying operations, coupling a motor to the hand-held portable misting sprayer for pressurizing HOCL through a spray nozzle for creating a mist, coupling electronic processing and communication modules to the hand-held portable misting sprayer and components for gathering, recording, processing data gathered, and transmitting the data to external digital devices wirelessly, and providing a hand-held/portable misting sprayer app for use on user digital devices for receiving and processing data transmitted from the hand-held portable misting sprayer.

traducir

PERSONAL PROTECTIVE EQUIPMENT SYSTEM FOR SAFE AIR, TRAIN OR BUS TRAVEL PROTECTING AGAINST INFECTIOUS AGENTS INCLUDING NOVEL CORONAVIRUS - COVID-19

NºPublicación: US2022008756A1 13/01/2022

Solicitante:

LANG NOAH [US]

US_2020376305_A1

Resumen de: US2022008756A1

Aspects of the invention relate to personal protection systems against COVID-19 including face masks and methods, systems or devices of managing, regulating and/or filtering airflow during travel on an aircraft, train, or bus.

traducir

SMART FACE PROTECTIVE DEVICE AND SYSTEM FOR INFECTION CONTROL

NºPublicación: US2022008763A1 13/01/2022

Solicitante:

SALEH AHMAD [AE]

Resumen de: US2022008763A1

There is provided a smart face protective device, preferably as part of a helmet or another head held device, to be used by a user for preventing or reducing spread of infectious droplets through a portal portion of the user's face, where the face protective device is configured to be automatically adjusted while being in use between a secured position and an unsecured position based on an electric signal associated to a monitored health and safety condition of the user. There is also provided a system, a network and a method for allocating smart face protective devices to members of a community and managing these devices and data collected thereby for preventing or reducing risks of virus contamination and spread, namely COVID-19, between the members of the community.

traducir

PRIMER SET FOR DETECTING SARS-COV-2, METHOD FOR TESTING SARS-COV-2, AND REAGENT AND KIT OF TESTING SARS-COV-2

NºPublicación: US2022010389A1 13/01/2022

Solicitante:

UNIV NAGASAKI [JP]
CANON MEDICAL SYSTEMS CORP [JP]

JP_6905235_B1

Resumen de: US2022010389A1

One embodiment according to the present invention relates to a primer set for detecting SARS-CoV-2, the set comprising a plurality of LAMP primers targeting one or more open reading frame (ORF) regions in a SARS-CoV-2 genome, wherein the one or more ORF regions are selected from the group consisting of Orf1b, OrfM, OrfN, and OrfS; and a technique relating to use of this primer set.

traducir

RAPID DIAGNOSTIC TEST

NºPublicación: US2022010386A1 13/01/2022

Solicitante:

DETECT INC [US]

Resumen de: US2022010386A1

Aspects of the disclosure relate to compositions and methods for amplifying and/or detecting one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens) in a biological sample obtained from a subject. In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. In some embodiments, the methods comprise isothermal amplification of a target nucleic acid and subsequent detection of the amplification products.

traducir

Modular recycling air curtain device to replace personal protection equipment (PPE) for reduction in the spread of viruses such as Covid-19.

NºPublicación: US2022010988A1 13/01/2022

Solicitante:

CASH JAMES T [US]
CASH OLIVIA Z [US]

Resumen de: US2022010988A1

A module air curtain and recirculation system that can be incorporated into various tables and workstations that provides 1) an effective air curtain between individuals, 2) a reduction of harmful viruses and 3) the ability for two or more people to be in close proximity without having to wear personal protective equipment such as face masks.

traducir

METHOD FOR THE RAPID IDENTIFICATION OF COVID-19 INFECTION

NºPublicación: US2022011309A1 13/01/2022

Solicitante:

UNIV ARIZONA STATE [US]
MARV ENTPR LLC [US]

Resumen de: US2022011309A1

An embodiment provides a method for identifying Covid-19 in a body fluid of a patient, including: removing the body fluid from a patient; applying a treatment to the body fluid, wherein the treatment comprises an antibody that joins with a Covid-19 targeted antigen (TA) in the body fluid to form an antibody-TA complex, wherein the antibody comprises a light functional antibody; identifying the antibody-TA complex, using a spectroscopic technique, from the body fluid using a light source; and returning the body fluid to the patient. Other aspects are described and claimed.

traducir

Influenza Status Registry

NºPublicación: US2022013200A1 13/01/2022

Solicitante:

MARZ KEITH [US]

US_2022013201_A1

Resumen de: US2022013200A1

An influenza Status Registry (ISR) that provides a method of acquiring, storing and displaying a person's status regarding influenza, particularly the COVID-19 coronavirus, as well as vaccination information. The ISR uses a software program that operates on a computer or a wireless device such as a smart phone or tablet computer. A person will have an influenza/COVID-19 test performed by a medical professional. The test results, which show the person's status, are then displayed on the computer or wireless device. Any business or other entity where multiple people congregate in a limited space then uses the ISR to determine if it is safe to allow each person to enter the location. The status will be displayed as never had, previously had or currently has influenza/COVID-19, and appropriate action can be taken based on the test results. Additionally, the ISR will display information pertaining to a person's vaccination status.

traducir

Business Model For A Computer Readable Medium

NºPublicación: US2022013201A1 13/01/2022

Solicitante:

MARZ KEITH [US]

US_2022013200_A1

Resumen de: US2022013201A1

A business model for a computer readable medium that provides a method of acquiring, to storing and displaying a person's status regarding viral infection, particularly the COVID-19 coronavirus, as well as vaccination information. The computer readable medium uses a software program that operates on a computer or a wireless device such as a smart phone or tablet computer. A person will have an viral infection/COVID-19 test performed by a medical professional. The test results, which show the person's status, are then displayed on the computer or wireless device. Any business or other entity where multiple people congregate in a limited space then uses the BMFCRM to determine if it is safe to allow each person to enter the location. The status will be displayed as never had, previously had or currently has viral infection/COVID-19, and appropriate action can be taken based on the test results. Additionally, the BMFCRM will display information pertaining to a person's vaccination status.

traducir

METHOD OF RAPID DETECTION AND MONITORING OF ANTI SARS-COV-2 ANTIBODIES

NºPublicación: EP3936866A1 12/01/2022

Solicitante:

SPECTRAL MED SOLUTION AG [CH]

Method and system for controlled hyperthermia

NºPublicación: US11219551B1 11/01/2022

Solicitante:

VERTHERMIA ACQUISITION INC [US]

Resumen de: US11219551B1

Methods and for treatment of cancer and other diseases including complications from late stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating rheumatoid arthritis, scleroderma, hepatitis, sepsis, the Epstein-Barr virus, and patients with life threatening complications from other viruses, including the COVID-19 virus. A method for removing viruses from the blood supply in an external circuit is also presented.

traducir

COVID-19 peptide specific T-cells and methods of treating and preventing COVID-19

NºPublicación: US11219684B1 11/01/2022

Solicitante:

TEVOGEN BIO INC [US]

US_11207401_B1

Resumen de: US11219684B1

The invention relates to pharmaceutical compositions that contain COVID-19 peptide specific cytotoxic T cells, and to methods for treating or preventing COVID-19 infection.

traducir

Intranasal MERS-CoV vaccine

NºPublicación: US11219685B1 11/01/2022

Solicitante:

UNIV KING ABDULAZIZ [SA]

US_2022008530_A1

Resumen de: US11219685B1

An immunogenic CD40-targeted trimeric MERS-CoV S1 fusion polypeptide as well as a corresponding polynucleotide encoding it and its use for safely inducing immune responses directed against MERS-CoV without inducing vaccine associated respiratory pathologies associated with non-targeted vaccines.

traducir

Compounds specific to coronavirus S protein and uses thereof

NºPublicación: US11220536B1 11/01/2022

Solicitante:

ADAGIO THERAPEUTICS INC [US]

US_2021388067_A1

Resumen de: US11220536B1

The present disclosure is directed to antibodies, and antigen binding fragments thereof, having binding specificity for the S protein of coronaviruses (CoV-S), such as the S protein of the SARS coronavirus (SARS-CoV-S) and/or the S protein of the SARS coronavirus 2 (SARS-CoV-2-S), including neutralizing antibodies and antibodies that bind to and/or compete for binding to the same linear or conformational epitope(s) on CoV-S. Further disclosed are conjugates of anti-CoV-S antibodies, and binding fragments thereof, conjugated to one or more functional or detectable moieties. Methods of making said anti-CoV-S antibodies and antigen binding fragments thereof are also contemplated. Other embodiments of the disclosure include the use of anti-CoV-S antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with coronaviruses, or the S protein thereof, and conditions where neutralization or inhibition of coronaviruses, or the S protein thereof, would be therapeutically and/or prophylactically beneficial.

traducir

ANTIVIRAL AGENTS FOR TREATMENT OF CORONAVIRUSES

NºPublicación: US2022000904A1 06/01/2022

Solicitante:

MEHARRY MEDICAL COLLEGE [US]

Resumen de: US2022000904A1

An antiviral agent is provided, having a phosphorodiamidate morpholino oligomer with an antisense sequence to a portion of a genome of a strain of a coronavirus. The coronavirus may be SARS-CoV-2 or another βCoV. The antiviral agent finds many uses, such as in a pharmaceutical composition, a method of treating coronavirus-mediated disease, a method of preventing coronavirus-mediated disease, a method of reducing or preventing the replication of coronavirus in a host cell, a method of controlling the spread of coronavirus in donated tissue, a treated tissue sample, and in the manufacture of a medicament for the treatment or prevention or coronavirus-mediated disease.

traducir

COMPUTATIONALLY-OPTIMIZED ACE2 PEPTIDES FOR COMPETITIVE INTERCEPTION OF SARS-CoV-2

Nº publicación: US2022002700A1 06/01/2022

Solicitante:

MASSACHUSETTS INST TECHNOLOGY [US]

Resumen de: US2022002700A1

Methods and compositions relating to an engineered peptide capable of binding to a biological molecule for viral inhibition. The engineered peptide is computationally-derived from soluble angiotensin-converting enzyme 2 (sACE2), a known receptor for viral spike proteins. The engineered peptide is optimized for minimal size and off-target effects. The engineered sACE2 peptide variants are a suitable targeting domain for fusion proteins of various effects.

traducir

Página1 de 22 nextPage por página

punteroimgVolver