BIOIMPRESIÓN 3D

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Resultados 180 resultados LastUpdate Última actualización 25/07/2022 [14:08:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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一种具有表面羟基磷灰石HA修饰微孔钛的腕关节假体

NºPublicación: CN217014349U 22/07/2022

Solicitante:

中国人民解放军联勤保障部队第九二〇医院

Resumen de: CN217014349U

本实用新型公开了一种具有表面羟基磷灰石HA修饰微孔钛的腕关节假体,包括:半球杯、桡骨柄、活动半球、腕骨平台、掌骨固定柄;本实用新型将钛合金(Ti6Al4V)的作为材料,以激光3D打印的方式进行一体制作,表面通过等离子喷涂技术进行HA涂层覆盖,HA涂层可以保证假体周围缓释钙磷离子,从而促进细胞成骨分化,做到更好的骨长入,解决中远期假体容易松动的问题,同时HA涂层可以使假体表面变得粗糙,也可以涂抹抗感染涂层,使假体本身具有抗菌能力,解决置换早期容易出现感染的问题;假体表面为逐层堆叠的锥形圆环设计,增加摩擦力提高抗拔出性能,桡骨组件与腕骨组件及两侧螺钉的表面,均具有HA涂层,以做到更好的骨整合。

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一种义齿3D打印机调节装置

NºPublicación: CN217021439U 22/07/2022

Solicitante:

义乌市筑真电子科技有限公司

Resumen de: CN217021439U

本实用新型公开了一种义齿3D打印机调节装置,主要涉及3D打印技术领域,包括壳体、调整机构,调整机构安装在壳体上,U型板上固定安装有叶片泵,中间圈和外侧圈转动安装在叶片泵上,内圈转动安装在叶片泵上,内圈上安装有控制阀组件,控制阀组件带动中间圈和外侧圈转动;当中间圈转动时控制滑动组件滑动,从而带动第一移动组件和第二移动组件滑动;支撑座固定安装在调节组件,支撑座用于安装激光器,通过第一移动组件和第二移动组件改变调节组件的位置,通过外圈使得调节组件带动支撑座改变高度,从而实现自动校准激光器的位置,本实用新型利用调整机构能自动调整激光器的位置,具有自动化程度高的优点。

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3D PRINTING OF LOW MELTING POINT MATERIALS

NºPublicación: CN114786617A 22/07/2022

Solicitante:

阿肯色州立大学托管会

WO_2021016494_A2

Resumen de: WO2021016494A2

A system and method that enables 3D printing of ballistics gel and other low melting point materials.

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用于盆腔肿瘤影像术前导航的图像识别系统

NºPublicación: CN114782454A 22/07/2022

Solicitante:

四川省肿瘤医院

Resumen de: CN114782454A

本发明涉及用于盆腔肿瘤影像术前导航的图像识别系统,包括:图像分割模块,用于对采集的MR盆腔图像进行盆腔肿瘤自动分割,以及对采集的同部位的CT图像进行盆骨骨骼自动分割;图像融合模块,用于将自动分割了盆腔肿瘤的MR盆腔图像和自动分割了盆骨骨骼的CT图像进行配准融合;3D打印模块,用于基于配准融合的MR盆腔肿瘤和盆骨骨骼,制定3D盆骨肿瘤模型,并根据3D盆骨肿瘤模型打印3D盆骨假体。本发明利用医学影像图像识别与深度学习结合,通过处理医学影像增强CT图像中的信息,通过图像识别盆腔CT肿瘤的情况及周围毗邻关系,完成在病灶识别的基础上实现对病灶细节及三维空间的深度剖析。

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一种可自固化的3D打印水凝胶墨水、制备方法以及组织工程支架

NºPublicación: CN114773628A 22/07/2022

Solicitante:

中山大学

Resumen de: CN114773628A

本发明提供了一种可自固化的3D打印水凝胶墨水的制备方法,包括如下步骤:步骤一、将高分子聚合物进行醛基化,得到醛基化的高分子聚合物,醛基含量用TNBS方法定量,醛基化度为1.0‑80.0%;步骤二、将三嵌段共聚物进行氧胺基团封端得到AOPF聚合物,用1HNMR表征氧胺的取代度,氧胺的取代度范围为1.0‑100.0%;步骤三、将醛基化高分子聚合物和氧胺基团封端的三嵌段聚合物分别溶于水溶液中;步骤四、将步骤三得到的溶液按照一定的醛基与氧胺官能团比混合,放置于一定温度的环境中进行凝胶一段时间,制备出双交联水凝胶墨水。本发明的水凝胶墨水是基于良好的温敏性和双交联方法制备的,在低温(4‑20℃)下凝胶仅以动态共价键交联,可以从3D打印机直接挤出;在高温(25‑50℃)下凝胶通过分子间的疏水作用自发形成二次交联,凝胶强度显著增强,提高了打印成品的保真度和稳定性。

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硅/锌离子掺杂双相磷酸钙陶瓷支架及其制备方法

NºPublicación: CN114767927A 22/07/2022

Solicitante:

华南理工大学

Resumen de: CN114767927A

本发明公开了一种硅/锌离子掺杂双相磷酸钙陶瓷支架及其制备方法,首先将合成的硅离子掺杂羟基磷灰石粉体与锌离子掺杂β‑磷酸三钙粉体混合,通过3D打印制备得到硅/锌离子掺杂双相磷酸钙陶瓷支架坯体,然后进行高温烧结得到硅/锌离子掺杂双相磷酸钙陶瓷支架;在此基础上,合成镁掺杂硅酸钙前驱体并制备成浆料,浆料浸渍支架渗透涂覆支架表面,重复涂覆和干燥,然后进行热处理,在支架表面形成镁掺杂硅酸钙表面层,最终得到表面改性的硅/锌离子掺杂双相磷酸钙陶瓷支架。本发明具有制备工艺较简单、离子的掺杂量和释放量可调节、多种活性离子协同促成骨和血管化等优点,对拓展磷酸钙陶瓷支架的临床应用具有重要意义。

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Schraubenelement und Verfahren zur additiven Herstellung

NºPublicación: DE102021000210A1 21/07/2022

Solicitante:

MIMEO MEDICAL GMBH [DE]

Resumen de: DE102021000210A1

Schraubenelement (1) und Verfahren zur Herstellung des Schraubenelements (1) für die Fixation von Knochenkomponenten und Knochenfragmenten bestehend aus einem Schaft (11) mit einem Knochengewinde (12) und eine sich am Schaft (11) entlang erstreckende longitudinale Zentralachse (103) und sich dadurch eine distale (102) und eine proximale (101) Richtung definiert, und das Schraubenelement (1) zusätzlich einen Kopf (10), einen Halsbereich (20) aufweist und eine Werkzeugansatzstelle (90) im Kopf (10) bereitgestellt wird, dadurch charakterisiert, dass am proximalen Ende des Kopfes (10, 109) mindestens drei Ausleger-Elemente (13) befestigt sind und diese Ausleger-Elemente (13) in proximaler Richtung (101) über das proximale Ende des Kopfes (10, 109) hinausreichen und hauptsächlich entlang der longitudinalen Zentralachse (103) angeordnet sind.

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A synthetic composite as bone graft and the method thereof

NºPublicación: AU2021226238A1 21/07/2022

Solicitante:

BONE SUBSTITUTES

WO_2021171315_A1

Resumen de: AU2021226238A1

The invention is for a synthetic composite for a bone graft comprising of: bio inert polymers comprising poly lactic acid, poly D, L-Lactic acid; bio active polymer consisting of polypropylene fumarate or diester of fumaric acid and propylene diol (1,2-Diol); and a bioactive inorganic component consisting of a metal fluorophosphates glass powder wherein the amount of the bioactive components is upto 30% (w/w) of the composite. The bioactive inorganic metal fluorophosphates glass powder of the composite is one of zinc fluorophosphate, magnesium fluorophosphate or silver fluorophosphate. The invention pertains to the method of making the scaffold, and also the 3D printed scaffold.

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FRICTION NANO-GENERATOR AND MANUFACTURING METHOD, SELF-POWERED SENSING SYSTEM AND MEASUREMENT METHOD FOR ANGLE OF JOINT

NºPublicación: WO2022151542A1 21/07/2022

Solicitante:

UNIV SHENZHEN [CN]

CN_112751502_A

Resumen de: WO2022151542A1

The present invention provides a friction nano-generator based on a 4D printing technology. The friction nano-generator comprises: a first substrate layer; a first friction power generation component of friction units, wherein several friction units are arranged at intervals by taking the geometric center of the first substrate layer as the circle center; and a second friction power generation component comprising a second substrate layer, first electrodes and second electrodes, wherein several first electrodes and several second electrodes are spaced apart from each other by taking the geometric center of the second substrate layer as the circle center, a gap is provided between each first electrode and each second electrode, and the first substrate layer and the second substrate layer are inserted together by means of a flange provided on the first substrate layer and a groove provided on the second substrate layer, so that the friction units are in contact and friction with the first electrodes and the second electrodes. The present invention further provides a self-powered sensing system, a measurement method for rotation angle of a joint, and a manufacturing method for a 4D printing friction nano-generator. The present invention solves the technical problem that a sensing apparatus has a complex manufacturing process and low preparation efficiency and precision, and the manufactured sensing apparatus has a short service life.

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ORAL DISINTEGRATING FILM WITH QR CODE APPLIED THERETO AND METHOD FOR PREPARING SAME USING 3D PRINTING TECHNOLOGY

NºPublicación: WO2022154476A1 21/07/2022

Solicitante:

UNIV AJOU IND ACADEMIC COOP FOUND [KR]

Resumen de: WO2022154476A1

The present invention relates to an oral disintegrating film with a QR code applied thereto and a method for preparing same using 3D printing technology. Specifically, provided are an orally disintegrating film and a method for preparing same, the orally disintegrating film comprising: an antipsychotic drug selected from aripiprazole, paliperidone, or paliperidone palmitate; polyethylene oxide as a film former; poloxamers as a solubilizing agent; and citric acid as an acidity regulator, wherein the orally disintegrating film is labeled with a QR code including patient information and drug information, or a website address (URL) containing the information. The oral disintegrating film with a QR code applied thereto, according to the present invention, can be prepared easily and simply by means of a 3D printer, and information about a patient and a drug can be easily learned by scanning the QR code applied to the oral disintegrating film through a smartphone, etc.

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MODIFIED-EXTRACELLULAR MATRIX-BASED HYDROGEL, METHOD OF PREPARING SAME, AND USE OF SAME

NºPublicación: WO2022154245A1 21/07/2022

Solicitante:

POSTECH RES & BUSINESS DEV FOUND [KR]

US_2022218465_A1

Resumen de: WO2022154245A1

A modified-extracellular matrix-based hydrogel according to one example of the present invention comprises an extracellular matrix-modified collagen complex formed by a Michael addition reaction between an extracellular matrix having an amine group, and a modified collagen having an ethylenically unsaturated bond functional group introduced therein. The modified-extracellular matrix-based hydrogel according to the present invention exhibits enhanced mechanical properties (e.g. viscoelasticity). In addition, the preparation of a bio ink by encapsulating cells in the modified-extracellular matrix-based hydrogel according to the present invention exhibits high cell viability. In addition, transplantable artificial biological tissues (e.g. artificial corneal tissues) fabricated by 3-D printing the bio ink according to the present invention, when transplanted in a damaged cornea, can be sutured and have a transparency similar to a real cornea, and due to enhanced mechanical properties, are capable of reconstructing corneal tissues without other adverse side effects.

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LEAD CONSTRUCTION INCLUDING ALIGNABLE MARKER ELEMENTS

NºPublicación: US2022226636A1 21/07/2022

Solicitante:

MEDTRONIC INC [US]

Resumen de: US2022226636A1

Implantable apparatus includes two or more alignable marker elements, and systems and methods for manufacturing such implantable apparatus, and methods to utilize such implantable apparatus. For example, the implantable apparatus may include a first alignable marker element and a second alignable marker element that may be used to ensure proper alignment with a target site.

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High Fatigue Strength Porous Structure

NºPublicación: US2022226897A1 21/07/2022

Solicitante:

HOWMEDICA OSTEONICS CORP [US]

AU_2018203479_A1

Resumen de: US2022226897A1

A porous apparatus includes a first layer and a second layer. The second layer has a plurality of struts. At least some of the struts define a porous geometry defining a plurality of faces, at least one of the plurality of the faces at least partially confronting the first layer. Each face is bounded by intersecting struts at vertices. Less than all of the vertices of each face of the porous geometry at least partially confronting the first layer are connected by a strut to the first layer. A process of producing the at least partially porous structure includes depositing and scanning metal powder layers. At least some of the scanned metal powder layers form either one or both of a portion of a first section of the structure and a portion of a second section of the structure formed by at least the struts defining the porous geometry.

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Pharmaceutical Dosage Forms and Method For Their Production

NºPublicación: US2022226248A1 21/07/2022

Solicitante:

DIHESYS DIGITAL HEALTH SYSTEMS GMBH [DE]

CN_114206313_PA

Resumen de: US2022226248A1

The invention relates to a method for producing solid or semi-solid dosage forms of pharmaceutical active ingredients. According to the method, an active-ingredient-free carrier structure is arranged in a 2D or 3D printing device and at least one pharmaceutical active ingredient is applied to at least one portion of the carrier structure by way of a 2D or 3D printing method carried out by the printing device. The invention also relates to semi-solid or solid dosage forms that are producible by the method according to the invention.

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System for body alignment through correction of malocclusions

NºPublicación: US2022226074A1 21/07/2022

Solicitante:

HA DANG [US]

Resumen de: US2022226074A1

The system for body alignment through tooth position addresses the lack of non-surgical treatment for head, neck, shoulder, and back pain by combining software that generates custom alignment protocols for each patient with a clear aligner embedded with powerful permanent magnets to pull teeth into the desired positions.

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NATURAL COMPOSITION COMPRISING ALGINATE AND CELLULOSE NANOFIBERS ORIGINATING FROM BROWN SEAWEED

NºPublicación: US2022227972A1 21/07/2022

Solicitante:

BERGLUND LINN [SE]
OKSMAN KRISTIINA [SE]

CA_3146152_PA

Resumen de: US2022227972A1

A natural composition for 3D printing comprising alginate from brown seaweed and cellulose nanofibers, wherein the cellulose nanofibers originate from cellulose from the same brown seaweed sample(s) as the alginate.

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Additive Method For 3D Printing Active Ingredient-Containing Objects

NºPublicación: US2022226250A1 21/07/2022

Solicitante:

DIHESYS DIGITAL HEALTH SYSTEMS GMBH [DE]

CN_114340596_PA

Resumen de: US2022226250A1

The present invention relates to an additive method for the production of solid or semi-solid two- or three-dimensional objects containing one of more pharmaceutical active agent(s), as well as to the objects produced by said method, such as semi-solid or solid dosage forms or medical devices. The method is a three-dimensional printing method in which individual defined volume increments are printed, which can be selected essentially freely as regards contained active agents, used carrier materials, shape, size, color, concentrations of active agents, and arrangement in the produced object.

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METHOD USING CUSTOM PATIENT SPECIFIC IMPLANTS TO DECREASE THE NATURAL RATE OF AGING SITE SPECIFIC REGIONS OF THE FACIAL SKELETON

NºPublicación: US2022226094A1 21/07/2022

Solicitante:

CHOTKOWSKI GREGORY C [US]
REEVE GWENDOLYN S [US]

Resumen de: US2022226094A1

Custom facial implants are used in a method to decrease and arrest the natural rate of aging in site specific areas of the facial skeleton in an individual by utilizing these custom facial implants in site specific areas, including the steps of: using CADCAM and 3D printing to create the custom patient facial implants; placing the custom implants on the site-specific areas of the facial skeleton through a transoral approach such that there are no external incision or scars on the patients face; such that the custom implants are surgically fixated directly to the bone and promotes integration of the implant to the underlying bone to prevent future changes to the facial skeleton in the specific facial areas to decrease or arrest the natural aging process such that the overlying soft tissue of the facial region is supported and resuspended by the custom facial implant

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A METHOD OF MANUFACTURING AN INTRAORAL DEVICE

NºPublicación: US2022226146A1 21/07/2022

Solicitante:

SOMNOMED LTD [AU]

WO_2020237316_A1

Resumen de: US2022226146A1

A method of manufacturing an intraoral device (1) including: obtaining an impression of at least one row of a patient's teeth; transferring said impression into a processor; said processor communicating with a milling machine; milling a blank of a first material to form a cavity in said blank substantially corresponding to said impression, said cavity being milled to include an offset; said cavity with at least a second material and allowing said second material to cure; milling said second material to correspond to said impression; milling said first material to obtain a device shape; cleaning said device (1); and wherein said first and second materials are comparatively hard and soft.

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SYSTEM FOR DESIGNING AND FABRICATING A CUSTOMISED DEVICE

NºPublicación: US2022226130A1 21/07/2022

Solicitante:

3DMORPHIC PTY LTD [AU]

AU_2022201602_A1

Resumen de: US2022226130A1

Disclosed herein are a method and system for producing a digital model of a customised device, comprising the steps of: importing a first digital file of a base part; importing a second digital file of a target shape; determining a warping interpolation function based on source point positions associated with the base part and target point positions associated with the target shape; and applying the warping interpolation function to the points of said base part to generate a model of said customised device.

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IMPLANT COMPONENTS AND METHODS

NºPublicación: US2022226122A1 21/07/2022

Solicitante:

SMITH & NEPHEW INC [US]

US_2022039961_A1

Resumen de: US2022226122A1

Systems, devices, and methods are provided for orthopedic implants. The implants may include a base member, such as an acetabular shell or an augment, that is configured to couple with an augment, flange cup, mounting member, or any other suitable orthopedic attachment.

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METHOD FOR PRODUCING A PROSTHETIC LINER AND SYSTEM CONSISTING OF PROSTHETIC LINER AND PROSTHETIC SOCKET

NºPublicación: US2022226129A1 21/07/2022

Solicitante:

OTTOBOCK SE & CO KGAA [DE]

DE_102019114461_B3

Resumen de: US2022226129A1

The invention relates to a method for producing a prosthetic liner for insertion into a prosthetic socket, which comprises a receptacle having a distal end and a proximal edge for a residual limb and the prosthetic liner. Said The method comprises determining a sealing lip contour on the outer face of the prosthetic liner which corresponds to a height contour of the proximal edge of the prosthetic socket, or on the basis of available, known anatomic characteristics of the residual limb and arranging a sealing lipon the outer face of the prosthetic liner along the determined sealing lip contour.

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Use of Engineered Renal Tissues in Assays

NºPublicación: US2022229045A1 21/07/2022

Solicitante:

ORGANOVO INC [US]

US_2020018747_A1

Resumen de: US2022229045A1

Disclosed are methods of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent renal injury by a potential toxic agent using a three-dimensional, engineered, bioprinted, biological renal tubule model. Also disclosed are methods of assessing the effect of an agent on renal function, the method comprising contacting the agent with a three-dimensional, engineered, bioprinted, biological renal tubule model. Also disclosed are models of renal disorder. In one embodiment, disclosed are models of renal fibrosis, comprising a three-dimensional, engineered, bioprinted, biological renal tubule model. Also disclosed are methods of making the model of renal disorder. In one embodiment disclosed are methods of making the model of renal fibrosis comprising contacting a three-dimensional, engineered, bioprinted, biological renal tubule model with an agent that is capable of inducing interstitial fibrotic tissue formation.

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A SODIUM ALGINATE, GELATIN, COLLAGEN AND FIBRIN (AGCF) BASED BIO-INK FOR THE BIOPRINTING OF A 3D BIOGEL-BASED TISSUE/STRUCTURE

NºPublicación: WO2022153319A1 21/07/2022

Solicitante:

THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO [IL]

Resumen de: WO2022153319A1

A bio-ink comprising: (a) at least one polysaccharide; (b) at least one structural protein; and (c) fibrinogen, wherein the polysaccharide is selected from a group consisting of Sodium alginate Chitosan, Hyaluronic acid, Gellan gum, Dextran, Agarose, Poly(ethylene glycol), Pluronic and Carrageenan and the structural protein is selected from a group consisting of Gelatin, Collagen Vitronectin, Laminins and Fibronectin.

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3D MODELING OF AN OBJECT USING TEXTURAL FEATURES

Nº publicación: EP4029471A1 20/07/2022

Solicitante:

3SHAPE AS [DK]

EP_3669819_A1

Resumen de: EP4029471A1

Disclosed is a method and a system for 3D modeling of a 3D object adapted to be inserted in or worn by a patient. The 3D modeling applies information of one or more features from an acquired 2D digital representation comprising textural data of the location where the 3D object is adapted to be arranged

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