TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 108 resultados LastUpdate Última actualización 14/10/2019 [17:05:00] pdf PDF xls XLS




Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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SYSTEM AND METHOD FOR INDUCTIVELY CHARGING A MEDICAL DEVICE

NºPublicación: US2019307952A1 10/10/2019

Solicitante:
TANDEM DIABETES CARE INC [US]

Resumen de: US2019307952A1

Methods and systems are disclosed wherein temperature in a device such as an ambulatory infusion pump is monitored during inductive charging of the device such that temperature-sensitive contents or components, such as, for example, insulin, particular circuitry and/or other components are not damaged. Temperature can be monitored in the device at one or more locations during inductive charging. If the temperature breaches one or more predetermined thresholds and/or is rising at a rate greater than one or more predetermined thresholds, charging can be suspended or provided at reduced power to prevent the temperature from further rising and damaging the contents and/or components of the device. One or more alerts associated with these events may also be triggered so that the user is aware of the situation and may take corrective action.



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SYSTEM AND METHOD FOR A CLOSED LOOP CONTROL IN AN ARTIFICIAL PANCREAS

NºPublicación: US2019307958A1 10/10/2019

Solicitante:
MEDTRUM TECH INC [CN]

Resumen de: US2019307958A1

The present invention provides a closed loop control method in an artificial pancreas and a system using the method, comprising sensing an activity level of a patient by at least one motion sensor and providing signals to at least one processer; then adjusting a series of related algorithms depending partly on the signals by the processer to provide more accurate and reliable data that is the basis of desirable treatment plans, and sending corresponding instructions by the processer for automatic operations of the artificial pancreas to realize a closed loop control.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: US2019307381A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307381A1

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: US2019307380A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307380A1

The sensor includes a working electrode having a first wire with a first flat surface and an electrochemical element on the first flat surface. A reference electrode includes a second wire with a second flat surface and a counter electrode includes a third wire with a third flat surface. The first wire is a first sensor wire for the working electrode, the second wire is a second sensor wire for the reference electrode and the third wire is a third sensor wire for the counter electrode in a plurality of sensor wires. The second flat surface and the third flat surface face toward each other.



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ENHANCED GLUCOSE LIMITING MEMBRANE FOR A WORKING ELECTRODE OF A CONTINUOUS BIOLOGICAL SENSOR

NºPublicación: US2019307379A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307379A1

Briefly, a sensor for a continuous biological monitor is provided that has a working electrode with a new interfere layer that is (1) non-electron conducting, (2) ion passing, and (3) permselective for molecular weight. The new interference layer is made by mixing a monomer and a mildly basic buffer, and then electropolymerizing the monomer and the buffer into a polymer. The polymer is deposited onto a working electrode for a continuous metabolic monitor, for example, using an electro depositing process in the form of cyclic voltammety (CV). The interference layer is permselectable for molecule size by adjusting the pH of the basic buffer.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: WO2019195661A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: WO2019195661A1

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.



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APPARATUS FOR REGULATING THE CONCENTRATION OF GLUCOSE IN THE BLOOD OF A PERSON

NºPublicación: EP3547917A1 09/10/2019

Solicitante:
INREDA DIABETIC B V [NL]

Resumen de: EP3329847A1

The invention relates to an apparatus for regulating the concentration of glucose in the blood of a person, said apparatus comprising: - at least one glucose sensor that is arranged to measure the glucose concentration of the person, for example in the interstitial fluid or blood; - a pump means for selectively introducing at least one substance influencing the blood glucose levels into the body of the person, for instance by means of at least one cannula or catheter to be inserted into the body of said person, and - a control means for controlling said at least one substance influencing the blood glucose levels to be introduced to the person based on data received from said glucose sensor, wherein said apparatus comprises at least one further sensor that is arranged to monitor a further characteristic of the person. The at least one further sensor may comprise an accelerometer, a heart rate sensor, a temperature sensor, a pH sensor, a ketone sensor, a GPS receiver and/or a skin resistance sensor.



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FLUID DELIVERY DEVICE WITH TRANSCUTANEOUS ACCESS TOOL, INSERTION MECHANISM AND BLOOD GLUCOSE MONITORING FOR USE THEREWITH

NºPublicación: EP3549524A1 09/10/2019

Solicitante:
INSULET CORP [US]

Resumen de: EP3549524A1

A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion. In certain embodiments, the fluid delivery device may comprise an infusion device comprising a fluid reservoir for containing a therapeutic fluid; and a transcutaneous access tool fluidly coupled to the fluid reservoir for delivering the therapeutic fluid subcutaneously and for introducing a monitoring test strip subcutaneously, and methods of use thereof.



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Capturing and Analyzing Hypoglycemic Event Data to Identify Treatment Options

NºPublicación: US2019298236A1 03/10/2019

Solicitante:
GLOOKO INC [US]

Resumen de: US2019298236A1

Systems, methods, and computer readable storage media manage low blood glucose levels. The system receives blood glucose readings, where each reading includes a blood glucose value and a respective timestamp. The system compares each blood glucose reading to a predefined hypoglycemic event threshold, and identifies hypoglycemic events when a respective blood glucose reading is below the predefined hypoglycemic event threshold. For at least a subset of the identified hypoglycemic events, the system prompts a user for information associated with each hypoglycemic event. The information requested includes one or more of: symptoms associated with the respective hypoglycemic event; perceived causes of the respective hypoglycemic event; and treatment for the respective hypoglycemic event. In response to the prompting, the system obtains feedback about the identified hypoglycemic events and provides a report that includes at least a subset of the obtained feedback.



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FLEXIBLE PATCH FOR FLUID DELIVERY AND MONITORING BODY ANALYTES

NºPublicación: US2019298921A1 03/10/2019

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2019298921A1

A wearable, conductive textile patch is provided that may include any of a number of features for monitoring body analytes and/or delivering fluids to a body. In one embodiment of the invention, a single, patch-mounted system monitors glucose levels of a diabetic person and provides appropriate doses of insulin in response to the glucose measurements. A hand-held user interface can be provided for wirelessly controlling the system and/or receiving information from it. Conductive pathways can be formed in the fabric of the patch. Components that can be integrated into the flexible patch include a power source, controller, transmitter, antenna, temperature and other sensors, fluid pump, infusion set, electrical pathways, switches, controls, electrodes, connectors, resistors and other circuit elements. Such components can be embedded, interwoven or coated on to the flexible patch instead of or in addition to surface mounting. Methods associated with use of the flexible patch system are also covered.



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INTEGRATION OF INFUSION PUMP WITH REMOTE ELECTRONIC DEVICE

NºPublicación: US2019298915A1 03/10/2019

Solicitante:
TANDEM DIABETES CARE INC [US]

Resumen de: US2019298915A1

A system and method can provide for a remote electronic device to be used to remotely initiate delivery of a medicament bolus with a medical device, such as an insulin pump, with the medical device providing audible or tactile confirmation of the programmed bolus. The bolus amount can be calculated by or programmed or otherwise entered into the smartphone, etc., and then transmitted to the medical device. When the pump receives the transmitted bolus amount, it issues one or more indications such as audible sounds and/or vibrations in any number of desired combinations. For instance, each individual sound or vibration may correspond to an increment of the medicament. The user can therefore determine the size of the medicament bolus by the number of sounds or vibrations and can confirm or cancel delivery of the bolus.



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CELL THERAPY FOR PATIENTS

NºPublicación: US2019298766A1 03/10/2019

Solicitante:
YANG DEMAO [US]

Resumen de: US2019298766A1

Materials and methods of treating a patient with type 2 diabetes mellitus, metabolic syndrome, obesity, infertility, high blood pressure, hyperthyroidism, and hypothyroidism, hyperlipidaemia, osteoporosis, osteoarthritis, hypoadrenalism, polycystic ovary syndrome, or Parkinson's disease comprising administering a therapeutically effective amount of ex vivo cultured activated peripheral blood mononuclear cells (PBMCs) to the patient. The ex vivo cultured activated cells are activated and cultured in a presence of a cytokine and may be autologous or allogeneic relative to the patient.



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GLUCOSE SENSORS AND METHODS OF MANUFACTURE THEREOF

NºPublicación: US2019300925A1 03/10/2019

Solicitante:
UNIV CONNECTICUT [US]

Resumen de: US2019300925A1

Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the working electrode; the first layer of the first hydrogel being operative to store oxygen; wherein the amount of stored oxygen is proportional to the number of freeze-thaw cycles that the hydrogel is subjected to; and a second layer of the second hydrogel. Disclosed too is a method that comprises using periodically biased amperometry towards interrogation of implantable glucose sensors to improve both sensor's sensitivity and linearity while at the same time enable internal calibration against sensor drifts that originate from changes in either electrode activity or membrane permeability as a result of fouling, calcification and/or fibrosis.



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METHOD FOR STABILIZING HEMOGLOBIN AND REAGENTS FOR PERFORMING THE SAME

NºPublicación: WO2019190787A1 03/10/2019

Solicitante:
EXACT SCIENCES CORP [US]

Resumen de: WO2019190787A1

A stool resuspension solution comprising a hemoglobin stabilization reagent is provided. In some embodiments, the hemoglobin stabilization reagent may be an osmolyte, a polyvalent cation, a sugar or polysaccharide and, optionally, a polyvalent cation, a protoporphyrin,or an HRP stabilization component and, optionally, a polyvalent cation. A method of stabilizing hemoglobin in a stool sample in the solution is also provided, as well as a sample collection device containing the solution.



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SYSTEMS AND METHODS FOR MANAGING GLYCEMIC VARIABILITY

NºPublicación: US2019298922A1 03/10/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019298922A1

Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.



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AUTOMATED SYSTEM FOR CONTROLLING THE BLOOD GLUCOSE LEVEL OF A PATIENT

NºPublicación: US2019298918A1 03/10/2019

Solicitante:
COMMISSARIAT ENERGIE ATOMIQUE [FR]

Resumen de: US2019298918A1

An automated system of regulation of a patient's blood sugar, including: a blood sugar sensor; an insulin injection device; and a processing and control unit capable of predicting the future evolution of the patient's blood sugar from a physiological model and of controlling the insulin injection device by taking the prediction into account, wherein: the physiological model includes a differential equation system describing the time variation of a plurality of state variables; and the processing and control unit is capable of implementing a step of automatic calibration of the physiological model including a step of estimation of initial values of the state variables by minimization of a quantity representative of the error, during a past observation period, between the blood sugar estimated based on the physiological model and the blood sugar measured by the sensor.



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METHOD AND DEVICES FOR PRESSURE DETERMINATION IN AN INSULIN PUMP

NºPublicación: US2019298916A1 03/10/2019

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: US2019298916A1

A method for connecting a force sensor to a circuit board is disclosed. A circuit board having first and second conductive leads located on the same surface of the circuit board is provided. Also provided is a force sensor with a first flexible contact tab having a first contact pad and a second flexible contact tab having a second contact pad. The first contact pad is arranged to face the first conductive lead. A first conductive rubber element establishes an electrical connection between the first contact pad and the first conductive lead, and the second contact pad and the second conductive lead are arranged to face in the same direction. A second conductive rubber element establishes an electrical connection between the second contact pad and the second conductive lead. Also disclosed are an associated device for determining fluid pressure in an insulin pump and an insulin pump.



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SYSTEMS AND METHODS FOR LEVERAGING SMARTPHONE FEATURES IN CONTINUOUS GLUCOSE MONITORING

NºPublicación: US2019298259A1 03/10/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019298259A1

The present embodiments harness a wide variety of capabilities of modern smartphones, and combine these capabilities with information from a continuous glucose monitor to provide diabetics and related people with more information than the continuous glucose monitor can provide by itself. The increased information provides the diabetic with an increased likelihood of good diabetes management for better health.



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System and method for body mass index relation to patient differing psychological stress effect on blood glucose dynamics in patients with insulin dependent diabetes

NºPublicación: AU2018221033A1 03/10/2019

Solicitante:
UNIVERSITY OF VIRGINIA PATENT FOUNDATION D/B/A UNIVERSITY OF VIRGINIA LICENSING AND VENTURES GROUP

Resumen de: AU2018221033A1

An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.



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CONTINUOUS GLUCOSE MONITORING INJECTION DEVICE

NºPublicación: US2019298920A1 03/10/2019

Solicitante:
BECTON DICKINSON CO [US]

Resumen de: US2019298920A1

An electronic insulin delivery device receives glucose data from a glucose monitor and sets a bolus dose amount. The device may take the form of an insulin pen with automatic priming and accurate dosing provided by a motor in connection with an encoder. The device may communicate with and be controlled by a smart phone device. The smart phone device provides a user interface to receive user data including patient weight, insulin to carbohydrate ratio and exercise factor, and to send instructions to the device, including dose amount. The dose amount is determined taking into account glucose level and trend, and other factors. The delivery device may be in continuous communication with the glucose monitor and smart phone to provide for near real-time adjustments in glucose treatment. Glucose data, insulin injection data, and other relevant data may be stored and accessible to interested parties.



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SYSTEMS AND METHODS FOR MANAGING DIABETES

NºPublicación: US2019298917A1 03/10/2019

Solicitante:
MALAVE LUIS [US]
KIM JESSE JAEJIN [US]

Resumen de: US2019298917A1

A method to dispense medication using one or more fillable medical dispensers by providing the medical dispenser with a first predetermined medication dosage sufficient for a first predetermined dispensing period, wherein the first dispensing period ends on a first repetitive day of the week for ease of remembrance by a user; providing the medical dispenser with a second predetermined medication dosage sufficient for a second predetermined dispensing period, wherein the dispensing period ends on a second repetitive day of the week for ease of remembrance; and installing the medical dispenser at least twice a week at a repetitive weekly replacement schedule.



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METHOD AND DEVICES FOR PRESSURE DETERMINATION IN AN INSULIN PUMP

NºPublicación: EP3545986A1 02/10/2019

Solicitante:
ROCHE DIABETES CARE GMBH [DE]
HOFFMANN LA ROCHE [CH]

Resumen de: EP3545986A1

A method, a device (110) and an insulin pump (112) are disclosed. The method for connecting a force sensor (122) to a circuit board (114) of an insulin pump (112) comprises step a): providing the circuit board (114), comprising at least one first conductive lead (116) and at least one second conductive lead (118), wherein the first conductive lead (116) and the second conductive lead (118) are located on the same surface (120) of the circuit board (114). The method further comprises step b) providing the force sensor (122) having at least one flexible first contact tab (124) and at least one flexible second contact tab (126), wherein each contact tab (124, 126) comprises a contact pad (128), wherein the contact pad (128) of the first contact tab (124) and the contact pad (128) of the second contact tab (126) are arranged on opposite sides relative to each other. The method further comprises step c) arranging the first contact tab (124) such that the contact pad (128) of the first contact tab (124) faces the first conductive lead (116) of the circuit board (114). Further, the method comprises step d) arranging a first conductive rubber element (130) such that an electrical connection between the contact pad (128) of the first contact tab (124) and the first conductive lead (116) is established. The method further comprises step e) arranging the second contact tab (126) such that the contact pad (128) of the second contact tab (126) and the second conductive lead (118) face in



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AUTOMATIC INSULIN INFUSION DEVICE

NºPublicación: KR101992165B1 30/09/2019

Solicitante:
이대로이동근이창형

Resumen de: KR101992165B1

본 개시는 초소형으로 제작하여 휴대가 용이하며 구조가 복잡하지 않아 비용이 저렴하고, 초소형 주입장치와 스마트폰의 연동을 통한 사용으로 사용법이 간단하고, 이로 인한 주사 모습의 타인에 대한 노출이 없어 프라이버시 보호 및 편리성이 극대하 되며, 주입장치와 스마트폰의 연동으로 컨트롤러가 없어 비용절감 및 휴대성이 높아지되, 어플리케이션을 이용한 입력값 주입 및 긴급정지의 2개의 버튼으로 간소화가 가능하며, 모터의 정밀제어를 통한 인슐량 주입량이 정교하고 쉽게 이루어지는 장점을 갖는 자동 인슐린 주입장치에 관한 것이다.본 개시의 실시예에 따른 자동 인슐린 주입장치는, 사용자의 신체에 부착하여 내부에 저장된 인슐린을 상기 사용자에 맞는 설정된 시간과 주입량으로 상기 사용자에게 투여되게 하는 펌프부 및 상기 펌프부와 무선으로 연결되어 조작을 통해 상기 펌프부가 상기 인슐린을 주입하도록 제어하는 것으로서, 상기 펌프부와 블루투스를 통해 무선으로 연동되며, 설정된 양만큼의 인슐린이 주입되도록 입력값을 주입하는 주입버튼과 긴급정지버튼의 간소화된 2개의 버튼으로 구비된 구동 화면을 갖는 애플리케이션 앱을 이용한 스마트 디바이스인 제어부를 포함하고, 상기 펌프부는, 휴



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SYSTEM FOR PREDICTING A PATIENT'S BLOOD GLUCOSE LEVEL

NºPublicación: WO2019180341A1 26/09/2019

Solicitante:
COMMISSARIAT ENERGIE ATOMIQUE [FR]

Resumen de: WO2019180341A1

The invention relates to an automated system for blood glucose level monitoring, having a processing and monitoring unit adapted to predict, from a mathematical model (501), the future trend of the blood glucose level G(t) of the patient, in which the model accepts as inputs: a variable EE(t) representative of the trend, over time, of the energy expended by the patient; a variable IOB(t) representative of the trend, over time, of the quantity of insulin taken on by the patient; and a variable COB(t) representative of the trend, over time, of the quantity of glucose taken on by the patient, and in which the mathematical model (501) is a model of the black box type, that is to say a non-physiological model defined solely by observation of the effects of the input variables EE(t), IOB(t) and COB(t) on the output variable G(t), without taking account of the various known physiological mechanisms acting within the body of the patient.



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BLOOD GLUCOSE TRACKING SYSTEM

Nº publicación: US2019290161A1 26/09/2019

Solicitante:
CHASE ARNOLD [US]

Resumen de: US2019290161A1

A blood glucose tracking system and method measures emitted microwave energy transmitted to and accepted by blood vessels in a desired target area of a patient in order to determine, in real time and in vivo, appropriate blood glucose levels. A measurement unit comprises a transmitter operatively connected to an antenna to deliver energy towards appropriate subcutaneous blood vessels. The measurement unit determines an accepted energy power value in the blood vessels associated with the desired target area. This measurement energy power value is compared with a calibration value, and the difference is used to determine a resultant blood glucose value. The determined blood glucose value may further be acclimatized using additional sensed values compensating for biological and ambient factors relevant to the patient. The final determined blood glucose value can be displayed for reading and/or transmitted and stored for recording for further reference.


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