Resumen de: GB2610612A

A wearable sensor device 100 for detecting a biological/physiological parameter (e.g. blood glucose, heart rate, blood pressure, respiration rate) of biological material 105 comprises a support structure 110 having a measurement region 115, and a radiofrequency (RF) element 130 and optical sensor 120 to respectively receive an RF signal and an optical signal 121 from the biological material 131 via the measurement region. The RF element is positioned between the optical sensor and the measurement region such that the optical sensor receives the optical signal through the RF element. The biological material is irradiated with RF radiation and optical radiation. The sensor may be worn on the skin web between a finger and thumb, earlobe, armpit, wrist or lip. The sensor may be a smartwatch 210 or smart bracelet. Additional sensors (e.g. temperature, motion, pressure) may be provided, and measurements used in combination with the optical and RF signals to determine the biological parameter.

Resumen de: US2023074617A1

A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement. In another embodiment, the device provides for toggling between two modes, with one mode that allows for display of glucose concentration values associated with the continuous glucose sensor and a second mode that prevents the display of glucose concentration values associated with the continuous glucose sensor.

Resumen de: US2023074650A1

The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used disposables, thereby allowing accurate and safe use and convenient maintenance.

Resumen de: US2023074949A1

The title of the invention is the remote sensing of physiological dynamics electromagnetic big data, the related technology belongs to the field of remote sensing of physiology or psychology. The technical problem to be solved by the present invention is the remote sensing of physiological or psychological electromagnetic dynamics of human, animal or plant individuals, the related electromagnetic media could be nucleon, electron, atom, molecule, ion, water, fluid, blood, DNA, RNA, amino acid, sugar, fat, protein, cell, tissue, organ, bone, fruit, flower, leave, stem, bark, and root, etc., the 30 μm-1000 million meters band electromagnetic waves could be used to extract the reflection spectra of partial or entire human, animal or plant individual electromagnetic media in different physiology or psychology states, single or multiple sensitive wavelengths or wavebands of spectrum troughs could be chosen as the electromagnetic wave probes, which could be used to irradiate partial or entire human, animal or plant individual electromagnetic media and extract the reflection waves, the electromagnetic dynamics of the human, animal or plant individuals in different physiology or psychology states could be transformed to the different electromagnetic indexes, such as the frequency, reflection rate and phase values, the major applications of the invention might be the drunk driving, fatigue driving, road rage driving, big data and big ecology, etc.

Resumen de: US2023074956A1

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.

Resumen de: US2023072422A1

Analyte sensing and response systems include a sensor detecting one or more analytes in a medium. The sensor uses decoupled transmit and receive elements or antennas to transmit a signal into the medium, and receive a response to the transmitted signal. An action that is based on the detection of the analyte is generated which can directly or indirectly affect the detected analyte in the medium. The action is automatically performed. The action can be increasing or decreasing flow from a source of the analyte, or of a chemical compound interacting with the analyte. An example of the action is controlling an insulin pump, where the analyte is glucose.

Resumen de: US2023071306A1

A computer-assisted medical device is configured and used to endoluminally navigate to a location in the gastrointestinal system and there treat certain body lumen wall areas while avoiding other body lumen wall areas. Embodiments ablate the inner mucosal layer and sub-mucosal nerve plexus of the stomach, duodenum and jejunum to effect treatment of insulin resistance and metabolic disorders, such as Type II diabetes (T2D), polycystic ovarian syndrome (PCOS), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), congestive heart failure (CHF) and obstructive sleep apnea (OSA). Various sensors are used to assist a clinical operator to navigate from the mouth through the pyloric sphincter and into and through the duodenum and/or jejunum. Various sensors are used to map and identify portions of the duodenum and/or jejunum. Various lumen wall ablation devices and methods are described. Various post-treatment assessments are described.

Resumen de: US2023070694A1

A device that non-invasively detects objects beneath or around the foot or a foot position and transmits signals which are processed and then output via an output device on a skin surface not affected by a neurological deficit, such as the hands or thighs. This device is suitable for subjects with diabetic neuropathy who have lost sensation in their feet and are at risk of punctures, cuts or other physical damage and at risk of sprains, strains or falls due to lack of an ability to detect objects underfoot and foot position.

Resumen de: US2023076499A1

The present disclosure relates to a method for transmitting/receiving biometric information in a continuous glucose monitoring system, and more specifically, to a method for transmitting/receiving biometric information, in which, in each communication cycle, first, an identifier of the last transmit packet received by a communication terminal is transmitted to a sensor transmitter, and the sensor transmitter transmits, to the communication terminal, a transmit packet generated after the last transmit packet, and thus biometric information generated by the sensor transmitter may be transmitted without loss to the communication terminal.

Resumen de: US2023074798A1

Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include an implantable microneedle array for use in measuring one or more analytes (e.g., glucose), such as in a continuous manner. The microneedle array may include, for example, at least one microneedle including a tapered distal portion having an insulated distal apex, and an electrode on a surface of the tapered distal portion located proximal to the insulated distal apex. At least some of the microneedles may be electrically isolated such that one or more electrodes is individually addressable.

Resumen de: US2023074713A1

An electronic device may include a housing and a PhotoPlethysmoGram (PPG) sensor disposed inside the housing. The PPG sensor may include a first Light Emitting Diode (LED) configured to generate light in a first wavelength band, a second LED configured to generate light in a second wavelength band, a third LED configured to generate light in a third wavelength band, a fourth LED configured to generate light in a fourth wavelength band, and a light receiving module including at least one photo diode. The electronic device may include a processor operatively coupled with the PPG sensor and a memory operatively coupled with the processor. The memory may include instructions that, when executed, cause the processor to measure optical densities of the light generated by the first LED to the fourth LED, and calculate a blood glucose value based at least in part on the measured optical densities.

Resumen de: US2023074154A1

A physiological characteristic monitoring system includes a wearable attachment device, an electronic device, and a physiological characteristic sensor (e.g., a glucose sensor) including a portion that is insertable into subcutaneous tissue of a user to generate sensor signals indicating a physiological characteristic of the user. The electronic device includes a first connector configured to detachably couple to the physiological characteristic sensor to receive the sensor signals in a first configuration of the electronic device, a second connector configured to detachably couple to the wearable attachment device in a second configuration of the electronic device, a controller configured to determine the physiological characteristic of the user based on the sensor signals, and a display configured to display the physiological characteristic of the user.

Resumen de: WO2023034705A1

Embodiments relate to a non-enzymatic glucose sensor. The non-enzymatic glucose sensor comprises one or more electrodes, a microfluidic channel, and at least one inlet, wherein the at least one inlet is configured to deliver a fluid to a microfluidic channel and wherein the microfluidic channel is configured to transport the fluid to the one or more electrodes. At least one of the one or more electrodes is a laser-induced graphene electrode, wherein the laser-induced graphene electrode comprises one or more uniform coatings of metal.

Resumen de: WO2023034122A1

A medical system including processing circuitry configured to assess a blood glucose level of a patient. The processing circuitry is configured to use a cardiac signal indicative of the electrical activity of the patient's heart and a temperature signal indicative of a body temperature of the patient. The cardiac signal may be, for example, an electrocardiogram (ECG), an electrogram (EGM), or another measure. The medical system is configured to determine a representative cardiac measure indicative of the cardiac signal and determine a representative temperature measure indicative of the temperature signal. The medical system is configured to assess when a blood glucose level of the patient may be outside a euglycemic range based on the representative cardiac measure and the representative temperature measure determined.

Resumen de: WO2023034820A1

Systems and methods for predictive glucose in accordance with embodiments of the invention are illustrated. One embodiment includes glucose management device, including a brain signal recorder, and a controller, including a processor, and a memory, the memory containing a glucose monitoring application configured to direct the processor to record a brain activity signal of a user's brain using the brain signal recorder, and decode the brain activity signal to predict future glucose levels of the patient.

Resumen de: WO2023034542A1

There is provided a glucose sensor system comprising: a transmitter (2) for containing a battery (212), the transmitter being for placement on top of patient skin; a transcutaneous connector (3) comprising at least one conductive path; and an implantable monolithic integrated circuit (1) for placement beneath the patient skin, wherein the implantable monolithic integrated circuit comprises a potentiostat and an electrochemical sensing element; wherein the potentiostat is electrically coupled to the transmitter (2) via the transcutaneous connector (3), and the electrochemical sensing element is configured to sense glucose concentration and generate an electrical signal representative of the glucose concentration, and wherein the potentiostat is electrically connected to the electrochemical sensing element.

Resumen de: WO2023030023A1

The present invention relates to a method for preparing a multifunctional hydrogel by means of yeast fermentation. The method of the present invention comprises: first reducing graphene oxide by using polydopamine to obtain a reduced graphene oxide solution, and then preparing a gelatin PCA glucose mixed solution having a certain concentration and an activated yeast solution; and mixing the three solutions by means of a one-pot reaction method, stirring evenly, pouring the mixture into a mold, and fermenting in a water bath at 30°C for a certain period of time to obtain a Gel-PrGO-PCA-yeast multifunctional hydrogel material. The method is simple, convenient, rapid and efficient, and the obtained hydrogel has good breathability, super-strong mechanical performance, conductivity and biocompatibility and can be applied to different skin positions to detect electrocardiograms and electromyograms. The present invention provides a new thought and method for preparing a porous breathable conductive hydrogel electrode, and is beneficial to the development and utilization of a conductive hydrogel material, so that the conductive hydrogel material can be used in the field of biosensors.

Resumen de: WO2023027667A1

The invention relates to the innovation in the part of the electronic measuring devices used for routine control of blood sugar in contact with the blood sample.

Resumen de: WO2023027250A1

A smart insulin-injecting device capable of measuring blood sugar, according to an embodiment of the present invention, comprises: a main body having a laser passage hole through which a laser for blood collection passes, and a strip insertion hole into which a blood measuring strip is inserted; a display disposed on the main body and displaying a blood sugar level according to blood collection; an insulin injection stick coupled to the main body and injecting insulin from a cartridge in which insulin is stored; and an operation unit disposed on the outer surface of the main body so as to be operated by a user.

Resumen de: WO2023028572A1

A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more compounds containing boronate or boronic acid moieties that reduce degradation of the analyte indicator.

Resumen de: US2023064614A1

One or more embodiments of the disclosure relate, generally, to a diabetes management system. Such a diabetes management system may include a flash glucose monitor and a user interface. The user interface may be configured to display one or more of graphical representations of glucose values and value representative of glucose measurements, and to change values displayed responsive to user interaction with the user interface.

Resumen de: US2023061350A1

Physiological parameters that related to the kinetics of red blood cell hemoglobin glycation, red blood cell elimination, and red blood cell generation within the body of a subject can be used, for example, to calculate a more reliable calculated HbA1c (cHbA1c), adjusted HbA1c (aHbA1c), and/or a personalized target glucose range, among other things, for subject-personalized diagnoses, treatments, and/or monitoring protocols. Such physiological parameters may be determined using a model that considers cross-membrane glucose transport and glycation.

Resumen de: US2023060490A1

The present development is a method and device to monitor the salt level in a patient's blood without the need of laboratory facilities or intervention by medical personnel. The basic device is designed to measure the concentration of analytes, specifically sodium ion and potassium ion, in the patient's blood and to communicate the analyte level to the patient essentially instantaneously through a mobile monitor or display screen. In a variation, the device combines the analyte-concentration measuring function with a means for measuring the concentration of glucose in blood, and the blood analyte level and glucose level are displayed to the patient essentially instantaneously. Both the salt level device and the salt level+glucose level device may be further adapted to allow for the salt and glucose level data to be stored in a data storage base so the patient has an historical record of the concentration levels.

Resumen de: US2023064839A1

Medical devices, systems, and methods related thereto a glucose monitoring system having a first display unit in data communication with a skin-mounted assembly, the skin-mounted assembly including an in vivo sensor and a transmitter. The first display unit and a second display unit are in data communication with a data management system. The first display unit comprises memory that grants a first user first access level rights and the second display unit comprises memory that grants a second individual second access level rights.

Resumen de: US2023065860A1

The present invention relates to evaluating the progress of a managed care organization's (MCO) patient wellness goals using a segmented patient population and patient self-reported medical readings. In operation, a wellness area and goal are predefined, and the patient's self-reported medical readings relate to the wellness area and goal. The patient population can be subdivided with a patient population segmentation rule creating a patient population recordset. An analysis is then performed on the patient population recordset to determine a ‘percentage of goal’ based on patient medical readings when compared to the predefined wellness goal. The ‘percentage of goal’ can be determined for the managed care organization as well as for individual patients, and individual healthcare facilities that are assigned to the managed care organization. Wellness areas that goals can be set for include hypertension, diabetes, body weight, body mass index, cholesterol, and other wellness areas.