BIOIMPRESIÓN 3D

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Resultados 129 resultados LastUpdate Última actualización 17/08/2019 [19:14:00] pdf PDF

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days

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METHODS OF MAKING AN ORAL APPLIANCE

NºPublicación: US2019247173A1 15/08/2019

Solicitante:

ZEGARELLI PETER JOHN [US]

Resumen de: US2019247173A1

An oral appliance and a method of making the oral appliance for delivering a medicament to an oral cavity are provided. The method comprises forming a non-porous material into a portion of the oral appliance; and applying a porous material to one or more discrete regions of the portion of the oral appliance to make the one or more discrete regions of the oral appliance porous thereby forming the oral appliance.

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NANO-DEVICES FOR SKIN AND MUCOSAL MACROMOLECULE DELIVERY AND DETECTION

NºPublicación: US2019247649A1 15/08/2019

Solicitante:

UNIV OF NORTH TEXAS [US]

Resumen de: US2019247649A1

In alternative embodiments, provided are products of manufacture and kits, and methods, for delivering macromolecules, including nucleic acids such as DNA and RNA, including genes and protein-encoding nucleic acids, to the skin, or the dermis or epidermis, and mucosa. In alternative embodiments, provided are products of manufacture and kits, and methods, for detecting macromolecules, including nucleic acids such as DNA and RNA, including genes and protein-encoding nucleic acids, in skin, epidermal or mucosal cells. In alternative embodiments, exemplary products of manufacture are physically flexible nanodelivery devices that are wearable, e.g., they can be worn as patches on the skin or mucosa. In alternative embodiments, nanodelivery devices provided herein are fabricated in a microelectrode—microfluidic—nanochannel configuration which can precisely deliver cargo into the ‘touched’ cells upon localized and safe-voltage electroporation. The on-skin electroporation can be wirelessly powered and controlled via on-chip near field communication (NFC) module. An accessory skin sensor can be simultaneously implemented on the same chip for skin impedance detection at the same time.

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PRINTING METHOD FOR THERMOPLASTIC RETENTION DEVICE PREFORM

NºPublicación: US2019248066A1 15/08/2019

Solicitante:

MEDTEC INC [US]

WO_2018084935_PA

Resumen de: US2019248066A1

A method for forming a preform for a thermoplastic retention device is provided. The method includes providing a thermoplastic base material and blending the base material with one or more chemical agents to form a polymer blend. The chemical agents are configured to modify a polymer chain of the base material when the polymer blend is exposed to radiation. The method further includes forming the polymer blend into a filament sized for a three-dimensional printing platform and printing a preform shape from the filament using the three-dimensional printing platform. After the printed preform is hardened, the method includes exposing the printed preform shape to radiation sufficient to cause a reaction between the one or more chemical agents and the base material.

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FORMING OF ADDITIVELY MANUFACTURED PRODUCT

NºPublicación: US2019248052A1 15/08/2019

Solicitante:

SMITH & NEPHEW INC [US]

US_10279521_PA

Resumen de: US2019248052A1

An exemplary process includes determining a desired pore size, selecting an initial pore size greater than the target pore size, manufacturing a porous structure with the initial pore size, forging the porous structure to form a forged part having the desired pore size, and forming an orthopedic device from the forged part.

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Fabrication of PCU/UHMWPE Polymeric Blends and 3D Printing Using the Same

NºPublicación: US2019247544A1 15/08/2019

Solicitante:

UNIV ARKANSAS [US]

Resumen de: US2019247544A1

The present invention relates to methods of fabricating PCU/UHMWPE blended filaments and medical implantable structures using 3D printing of polymeric material, such as PCU/UHMWPE blend structures. The 3D printer dispenses said polymeric material in a layer-by-layer manner to create said medical implant. Polymeric material is dispensed at up to 100% infill. In one embodiment, the layer-by-layer dispensing is at a reduced speed for the bottom and top 1 to 10 layers.

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THREE DIMENSIONAL PRINTED MOLD FOR ELECTROCHEMICAL SENSOR FABRICATION, METHOD AND RELATED SYSTEM AND DEVICES THEREOF

NºPublicación: US2019246923A1 15/08/2019

Solicitante:

UNIV VIRGINIA PATENT FOUNDATION [US]

WO_2018035238_A1

Resumen de: US2019246923A1

A method for preparing microsensors (e.g., microelectrodes) suitable for use in electrophysiology and electrochemistry studies in vitro and in vivo is described. The method can involve preparing a polymeric resin-insulated electron conducting fiber using a 3D printed mold comprising one or more channels, wherein each of the channels includes a tapered section. An electron conducting fiber partially enclosed within a metal or glass support can be laid in a channel; and a polymeric resin can be poured into the channel and cured, providing a polymer-insulated electron conducting fiber having a tapered section in proximity to a polymer-free electroactive tip area. For example, the method can be used to provide a polyimide-insulated carbon fiber microsensor. The mold can be used for the batch fabrication of the microsensors. The microsensors themselves, the molds for making the microsensors, and methods of using the microsensors are also described.

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LAPAROSCOPY TROCAR

NºPublicación: US2019247088A1 15/08/2019

Solicitante:

CAREWILL LDA [PT]

WO_2018041897_PA

Resumen de: US2019247088A1

There is disclosed a laparoscopy trocar, having a cannula and an obturator for use in inserting the cannula into the abdominal cavity of a patient. The cannula comprises a fluid control valve for opening and closing a fluid flow path from outside the bore of the cannula into the bore of the cannula and the obturator comprises a control means configured to cause the fluid control valve to move between its open and closed positions upon insertion of the obturator into the cannula. A novel tip for the obturator is disclosed comprising a concave bladed front edge formed between a pair of concave tip faces.

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Method For 3-D Printing A Custom Bone Graft

NºPublicación: US2019251217A1 15/08/2019

Solicitante:

GREYF ARTHUR [US]
BALAKO IRINA [US]

Resumen de: US2019251217A1

A method for producing bone grafts using 3-D printing is employed using a 3-D image of a graft location to produce a 3-D model of the graft. This is printed using a 3-D printer and a printing medium that produces a porous, biocompatible, biodegradable material that is conducive to osteoinduction. For example, the printing medium may be PCL, PLLA, PGLA, or another approved biocompatible polymer. In addition such a method may be useful for cosmetic surgeries, reconstructive surgeries, and various techniques required by such procedures. Once the graft is placed, natural bone gradually replaces the graft.

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METHOD FOR MANUFACTURE OF A REMOVABLE DENTAL PROSTHESIS BY MOULDING WITH THE AID OF A MOULD FORMED BY ADDITIVE MANUFACTURE

NºPublicación: US2019247167A1 15/08/2019

Solicitante:

MOJITO [FR]

JP_2019520158_A

Resumen de: US2019247167A1

Disclosed is a method for manufacture of a removable dental prosthesis by moulding, the method including: digital modelling of a prosthesis model; a step of producing a mould including a lower half-shell corresponding to a tooth part of the prosthesis and an upper half-shell corresponding to a gum part of the prosthesis, the two half-shells being able to be joined together by affixing one to the other, thereby forming an impression of the prosthesis, the step including digital modelling of a model of the mould, followed by additive manufacture of at least the lower half-shell, and a step of producing the prosthesis, the step including in succession at least one provision of at least one artificial tooth, positioning of the artificial tooth in a seat of the lower half-shell, assembling the mould and pouring a filler material into the mould. Also disclosed is a prosthesis obtained by this method.

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METHOD OF PRODUCING A MULTI-LAYERED PRINTED ABSORBENT ARTICLE

NºPublicación: US2019247239A1 15/08/2019

Solicitante:

PROCTER & GAMBLE [US]

US_2018221215_A1

Resumen de: US2019247239A1

A method for producing a multi-layered absorbent articles is disclosed. At least two of the layers include a colored region.

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TISSUE PRINTER

NºPublicación: EP3522828A1 14/08/2019

Solicitante:

GOVERNING COUNCIL UNIV TORONTO [CA]
SUNNYBROOK RES INSTITUTE [CA]

CN_109922755_A

Resumen de: WO2018064778A1

Disclosed herein is a bioprinter that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface, such as skin wounds. In handheld configurations of of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printhead and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. Different embodiments of the instrument are disclosed for m vivo application in small animals, as well as for large animal and clinical application. A stationary embodiment of the instrument is well suited for the continuous formation and roll-to-roll processing of planar biomaterials and tissues.

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MICROSTRUCTURED COMPOSITE PARTICLES

NºPublicación: EP3524279A1 14/08/2019

Solicitante:

SCHAEFER KALK GMBH & CO KG [DE]

US_2014004348_A1

Resumen de: WO2012126600A2

Microstructured composite particles obtainable by a process in which large particles are bonded to small particles, wherein - the large particles have a mean particle diameter in the range from 0.1 µm to 10 mm, - the mean particle diameter of the small particles is at most 1/10 of the mean particle diameter of the large particles, - the large particles comprise at least one polymer, - the small particles comprise at least one calcium salt, - the small particles comprise precipitated calcium carbonate particles having a mean particle size in the range from 0.01 µm to 1.0 mm and/or the large particles comprise at least one absorbable polyester having a number-average molecular weight in the range from 500 g/mol to 1 000 000 g/mol. The composite particles are preferably used as an additive, especially as a polymer additive, as an additive or starting material for the production of components, for applications in medical technology and/or in microtechnology and/or for the production of foamed articles.

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一种具有药物缓释功能的3D打印支架

NºPublicación: CN110115651A 13/08/2019

Solicitante:

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Resumen de: CN110115651A

本发明公开了一种具有药物缓释功能的3D打印支架,包括支架本体和聚合物层,所述支架本体外侧凹设有多个置药槽,所述置药槽内放置有缓释药球;所述支架本体包括多个同轴设置的支撑环和连接相邻支撑环的连接杆,所述支架本体外侧围设有聚合物层。制备方法:(a)获取病变血管的形态数据,确定血管支架的结构;(b)通过3D打印设备制备所述支架本体坯体;(c)通过激光雕刻,雕刻出置药槽,随后将缓释药球放置在置药槽中;(d)在所述支架本体的外侧打印出聚合物层,制得所述支架。缓释药球在植入的一定时间段之后才开始释放,延长血管支架的释放药物的时间。

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一种3D打印可降解血管支架的制备方法

NºPublicación: CN110115648A 13/08/2019

Solicitante:

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Resumen de: CN110115648A

本发明公开了一种3D打印可降解血管支架的制备方法,包括以下步骤,(a)建立模芯和血管支架的三维模型;(b)制备模芯;再通过静电纺丝制备明胶层,并将明胶层打磨光滑;向干净的3D打印设备中加入聚乳酸和聚己内酯的混合物,进行第二次3D打印,在模芯的明胶层上打印出支架本体;在支架本体完全固化前,在支架本体的两端打印出显影环;(c)将载药混合液超声喷涂在支架本体的外表面;去除模芯,得到中空管状的血管支架。3D打印技术与超声喷涂相结合,既能个性化的制备支架,又能将药物均匀的负载在支架上,并且,支架本体为可降解的高分子材料,在体内可降解,减少后遗症。

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一种三维打印护具及其打印方法

NºPublicación: CN110115652A 13/08/2019

Solicitante:

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Resumen de: CN110115652A

本发明属于医学康复护具及制作方法,具体涉及一种三维打印护具及其打印方法,能够解决现有护具不方便根据患处变化进行调节的问题。由基于增材制造的两部分主体拼合而成,两者之间通过固定环和锁定柱配合,用来连接固定及限位,能根据病人患处进行形状设计,贴合度好、重量轻、强度高且保护性好。尤其是固定环与锁定柱形成的固定装置,仅需将固定环套入后进行旋转即可顶紧两部分锁定柱完成固定,安装拆卸简便且使用方便,另外还可以根据患处不同时期的肿胀程度配合不同的固定环进行松紧调节,有效防止骨位移等问题。整个护具拼合定位准确,不易发生错位现象,对患处的紧固更加可靠,具有适用于各种患处的特点。

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聚氨酯材料及其制备方法和应用、聚合物材料、3D支架

NºPublicación: CN110117348A 13/08/2019

Solicitante:

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Resumen de: CN110117348A

本发明公开了一种聚氨酯材料及其制备方法和应用、聚合物材料、3D支架,涉及新材料技术领域。聚氨酯材料主要由预聚物A经扩链剂扩链得到,扩链剂包括表面带羟基的碳材料或其类似物;预聚物A的结构通式为式1结构,其中,X为—(CHCH)—或Y为任选取代的C1‑C12烷基、任选取代的C1‑C12环烷基、任选取代的C6‑C12芳族基、任选取代的C6‑C12杂环基或任选取代的C6‑C12杂芳基;m,n代表各自的聚合度;预聚物A的数均分子量为250‑20000。本发明将碳材料制成双亲性的聚氨酯,能够针对多种有机/无机的材料加工体系进行材料改性增强,能够显著增加材料的力学性能和生物相容性。

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POST-PROCESSING ARRANGEMENT FOR MOULDED ARTICLES MANUFACTURED IN A GENERATIVE MANNER BY MEANS OF PHOTOPOLYMERISATION

NºPublicación: CN110116501A 13/08/2019

Solicitante:

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US_2019240924_A1

Resumen de: US2019240924A1

The present invention relates to a post processing arrangement for shaped bodies manufactured additively by photopolymerization, which has a cleaning station for cleaning and a finishing station for post-exposure of the shaped body, characterized in that the cleaning station and the finishing station are housed in a housing (2), capable of standing on a horizontal stand surface, in which the cleaning station (22) is housed in a lower section (20) and the finishing station (42) is housed in an upper section (40) lying vertically above it, wherein the lower and upper sections can be connected to each other by a passage with a closure (24) which can be opened, in that a vertical lifting apparatus (44) with a vertical guide (46) and a holder (48), vertically displaceable thereon, to which the shaped body (1) can be directly or indirectly secured, runs through the finishing station in order to be able to transport the shaped body back and forth between cleaning station (22) and finishing station (42), in that a control apparatus (4) integrated into the housing is set up to control the operation of the lifting apparatus (44), the closure (24) and the cleaning and finishing stations such that, after the shaped body (1) has been positioned on the holder and after the closure (24) has been opened, the lifting apparatus (44) lowers the shaped body into a basin (26) of the cleaning station (22); to control the operation of the cleaning station for cleaning the shaped body; after complet

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一种变厚度的隐形矫治器的设计方法

NºPublicación: CN110101469A 09/08/2019

Solicitante:

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Resumen de: CN110101469A

本发明提供了一种变厚度的隐形矫治器的设计方法,属于牙齿正畸技术领域,包括以下步骤:获取患者的牙颌数字模型;在所述牙颌数字模型的基础进行牙齿分割;制定初步矫治方案,在软件中进行虚拟排牙;制定最终矫治方案,依据所述最终矫治方案得到一系列的所述牙颌数字模型;生成变厚度的隐形矫治器数字模型;将所述变厚度的隐形矫治器数字模型传输给3D打印机,面向直接3D打印制作变厚度的隐形矫治器。本发明提供的一种变厚度的隐形矫治器的设计方法,通过设计矫治器的厚度达到精确控制施力位置及大小的目的。

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METHOD AND APPARATUS FOR WEIGHTED RANDOM PATTERN PRINTING ON ABSORBENT ARTICLE COMPONENTS

NºPublicación: CN110114225A 09/08/2019

Solicitante:

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US_2018200118_PA

Resumen de: WO2018136391A1

Disclosed are methods and apparatuses for inkjet printing including printing graphics on an absorbent article component, comprising the steps of: providing one or more printheads; providing a substrate extending in a machine direction, the substrate comprising a first surface and an opposing second surface and defining a width in a cross direction; advancing the substrate in the machine direction past the one or more printheads; ejecting one or more inks from the one or more printheads onto the first surface of the substrate to define a graphic of a plurality of images, each of the plurality of images not being identical to another; wherein the distribution of each of the plurality of images printed on the substrate are not all equal to each other.

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一种基于3D打印的骨折外固定支具及其制造方法

NºPublicación: CN110101445A 09/08/2019

Solicitante:

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Resumen de: CN110101445A

本发明公开了一种基于3D打印的骨折外固定支具及其制造方法,其固定支具包括第一支架、第二支架、钢针,第一支架、第二支架装配为一体;第二支架、第一支架至少其中一个上设置有底座,底座上设置有固定孔、卡槽、底座通孔,固定孔与底座通孔连通;底座通孔内安装有固定塞,固定塞上分别设置有限位环、锁紧孔、钢针通孔,限位环不能穿过底座通孔;固定塞设置有锁紧孔的部分装入底座通孔内,且锁紧孔与固定孔连通,钢针一端穿过钢针通孔、穿刺过皮肤和肌肉后与骨头装配固定,而钢针另一端上设置有外螺纹;外螺纹可与设置在调节螺母上的螺纹孔通过螺纹旋合装配,卡槽可与卡合半轴卡合装配,卡合半轴设置在卡紧件上,卡紧件上还设置有受力部分。

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一种个性化股骨转子间旋转截骨手术导板

NºPublicación: CN209220408U 09/08/2019

Solicitante:

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Resumen de: CN209220408U

一种个性化股骨转子间旋转截骨手术导板,设置有与股骨解剖形态匹配的主体截骨定位导板、定位杆、与股骨解剖形态匹配的角量定位板和角量器。该个性化股骨转子间旋转截骨手术导板中,主体截骨定位导板具有三个截骨槽,能够精确进行截骨,角量定位板和角量器的配合可以实现准确的调节旋转角度。该个性化股骨转子间旋转截骨手术导板能够大大简化手术流程同时缩短手术时间,并且减少术中透视次数及术后并发症,缩短学习曲线,具有广阔的临床应用前景。

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METHOD AND DEVICE FOR PROVIDING A CONTROL COMMAND SET

NºPublicación: DE102018201739A1 08/08/2019

Solicitante:

EOS GMBH ELECTRO OPTICAL SYSTEMS [DE]

WO_2019149612_A1

Resumen de: WO2019149612A1

The invention relates to a method for providing a control command set for an additive manufacturing device for producing at least one three-dimensional object, the at least one object being produced layer by layer in the additive manufacturing device by solidifying a construction material at the locations corresponding to the cross-section of the object within a layer, said method comprising at least the following steps: providing a parameter set, which consists of a number of parameters, and a construction rule, which is suitable for describing at least one section of the object by means of the parameter set geometrically as a number, preferably a plurality, of linear or flat elements in space, which in the case of a plurality are particularly preferably similar, in particular identical; generating a computer-based layer model of the section of the object by determining, for each layer, the position and shape of a cross-section of the section of the object within said layer; generating a control command set for an additive manufacturing device by means of which the production of the section of the object is implemented on the basis of the layer model.

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CATHETER TUBE

NºPublicación: US2019240456A1 08/08/2019

Solicitante:

RIOCATH MEDICAL DEVICES A S [CZ]
USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I [CZ]

EA_201900113_A1

Resumen de: US2019240456A1

A catheter that has a catheter tube everting inside-out during the process of catheterization. The catheter tube has a plurality of longitudinal protrusions extending from the first end of the catheter tube through at least a portion of the catheter tube, and forming an angle of 0 degrees to 45 degrees with respect to the longitudinal axis of the catheter tube and facing radially inwards, and provides for dilating a circumference of the catheter tube upon everting the catheter tube inside-out from the first end of the catheter tube.

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SYSTEM AND METHOD FOR FORMING A BIOLOGICAL MICRODEVICE

NºPublicación: US2019240658A1 08/08/2019

Solicitante:

UNIV CENTRAL FLORIDA RES FOUND INC [US]

Resumen de: US2019240658A1

A method for forming a biological microdevice includes applying a biocompatible coarse scale additive process with an additive device and a biocompatible material to form an object. The coarse scale is a dimension not less than about 100 μm. The method also includes applying a biocompatible fine scale subtractive process with a subtractive device to the object. The fine scale is a dimension not greater than about 1000 μm. The method also includes moving the object between the additive device and the subtractive device. A system is also provided for performing the above method and includes the additive device, the subtractive device, a means for transporting the object between the additive device and subtractive device and a processor with a memory including instructions to perform one or more of the above method steps.

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SYSTEM AND METHOD OF MANUFACTURE FOR SPINAL IMPLANT

Nº publicación: US2019240782A1 08/08/2019

Solicitante:

WARSAW ORTHOPEDIC INC [US]

Resumen de: US2019240782A1

A build plate system includes a body defining at least one cavity. An insert is sized and shaped to fit within the at least one cavity such that the at least one cavity orients the insert for forming at least a portion of a screw shaft thereon by a manufacturing method using an additive manufacturing apparatus. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

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