BIOIMPRESIÓN 3D

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Resultados 157 resultados LastUpdate Última actualización 28/11/2022 [19:00:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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MODIFIED 3D-PRINTED OBJECTS AND THEIR USES

NºPublicación: US2022371268A1 24/11/2022

Solicitante:

LUNG BIOTECHNOLOGY PBC [US]

WO_2022236116_PA

Resumen de: US2022371268A1

Provided herein are methods which alter the mechanical and biological properties of polymeric materials. Also provided are compositions comprising the polymeric materials having said properties.

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Method for Optimization of Orthopedic Component Design

NºPublicación: US2022370141A1 24/11/2022

Solicitante:

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RES [US]

WO_2021067390_A1

Resumen de: US2022370141A1

Methods for understanding external and internal anatomy of bones through the use of imaging data and 3D modeling to facilitate the design of anatomically correct plates, devices and implants are disclosed. In one aspect the method results in an implant or plate that includes at least one curved surface wherein a contour of the at least one curved surface corresponds to an anatomic shape of a subject. The anatomic shape of the subject being determined based on an image of the bone.

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METHOD FOR MAKING AN ORTHODONTIC BRACKET

NºPublicación: WO2022246420A1 24/11/2022

Solicitante:

BRIUS TECH INC [US]

Resumen de: WO2022246420A1

Orthodontic devices and associated systems and methods are disclosed herein. In some embodiments, orthodontic devices of the present technology comprise brackets that are custom- shaped to a patient's teeth and/or include surface features such that the brackets bond strongly to the patient's teeth. A method of manufacturing a bracket can include selectively reducing a surface roughness of the bracket. In some embodiments, the bracket can be formed by an additive manufacturing process and/or support structures formed with the bracket during the additive manufacturing process can be used as a mask to prevent a surface roughness of certain regions from being reduced.

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CROSSLINKED BIORESORBABLE POLYESTER NETWORKS

NºPublicación: WO2022243567A1 24/11/2022

Solicitante:

UNIV GENT [BE]

Resumen de: WO2022243567A1

The present invention relates to the field of bioresorbable crosslinked materials. More specifically, the present invention pertains to a combination comprising a polyester having a crystalline backbone and at least one end-capping group attached to a first crosslinkable group and a compound comprising a second crosslinkable group, a crosslinked polyester wherein said combination forms a crosslinked network, a process of manufacturing thereof and the use of said crosslinked polyester.

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RETAINER FOR AN ORTHODONTIC TREATMENT AND METHOD FOR PRODUCING A RETAINER OF THIS TYPE

NºPublicación: WO2022242800A2 24/11/2022

Solicitante:

CYRON RENE [DE]

DE_102021112795_PA

Resumen de: WO2022242800A2

A retainer (5) generally consists of a plurality of individual or optionally contiguous double wings (6). Each double wing (6) consists of a middle piece (7) and two wings (8), which laterally adjoin the middle piece and are designed for surface-to-surface adhesive bonding to the peripheral surface of a tooth (1, 2). This middle piece (7) is set, approximately at half the height of the tooth crown, between two teeth (1, 2), where the middle piece extends, as far as possible and sharply, into the gap between the teeth (1, 2). The two wings (8) follow the gingival margin (4) and end approximately in the sagittal plane (9) of a tooth. In order to produce a retainer (5), an electronic image of the intraoral side of a tooth-row contour is captured and said electronic image is used to produce a customized retainer (5), for example by means of a 3D printer or a 3D milling machine, i.e. for example to print or to mill the customized retainer. If the adhesive bond of a double wing (6) loosens over time, the adhesive bond of said double wing can be restored without the entire retainer (5) having to be detached from the teeth (1, 2). If a double wing is damaged or lost, the function of the retainer is substantially maintained even at the affected tooth.

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RECORDING DEVICE

NºPublicación: US2022370657A1 24/11/2022

Solicitante:

SEIKO EPSON CORP [JP]

Resumen de: US2022370657A1

A recording device includes: a medium accommodation portion configured to accommodate a plurality of media; a feeding portion configured to send out the media from the medium accommodation portion; a recording section configured to perform recording on the media sent out from the medium accommodation portion; an ultraviolet-light emitting portion provided at a position opposed to the medium accommodation portion and configured to emit ultraviolet light toward the media accommodated in the medium accommodation portion; and a control unit configured to control the ultraviolet-light emitting portion to emit ultraviolet light to the media by utilizing a period before the feeding portion starts to feed the media.

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GEOMETRICALLY COMPLEX INTRAVAGINAL RINGS, SYSTEMS AND METHODS OF MAKING THE SAME

NºPublicación: ES2928873T3 23/11/2022

Solicitante:

THE UNIV OF NORTH CAROLINA AT CHAPEL HILL

US_2022168218_A1

Resumen de: WO2017165624A1

Geometrically complex intravaginal rings, systems and methods of making the same are provided herein. Disclosed herein are geometrically complex intravaginal rings with tunable and enhanced drug release, which in some embodiments can be fabricated by 3D printing technologies. The disclosed IVRs include a ring structure comprising a plurality of unit cells or macroscopic and/or microscopic architecture, which can be tuned to control the loading capacity of an active compound within the IVR, the diffusion of an active compound from the IVR, the surface area of the IVR, and/or the mechanical properties of the IVR. The disclosed geometrically complex IVRs can provide superior control over drug loading and drug release compared to conventional IVRs fabricated by injection molding or hot-melt extrusion.

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PROCESS FOR THE MANUFACTURE OF A SOLID PHARMACEUTICAL ADMINISTRATION FORM

NºPublicación: EP4091796A1 23/11/2022

Solicitante:

MERCK PATENT GMBH [DE]

ES_2926490_T3

Resumen de: EP4091796A1

The present invention relates to a process for the preparation of a solid pharmaceutical administration form using a 3D printing process as well. The process is a printing process that allows the production of solid pharmaceutical administration forms in a flexible manner and in conformity with the high quality standards required for the production of pharmaceuticals.

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METHOD OF MANUFACTURING DENTAL PROSTHESES AND DENTAL PROSTHESES

NºPublicación: EP4091576A1 23/11/2022

Solicitante:

LABORATORIO DIGITAL HIGH TEETH S L [ES]

KR_20220143660_PA

Resumen de: EP4091576A1

The present invention describes a method for the manufacture of dental prostheses where traditional artisanal or purely manual techniques are combined or merged with other more recent ones based on digital design, which comprises obtaining a digital image of the patient's mouth, digitally designing the dental pieces (1) and the gum (4) in a personalized way for each patient, manufacturing both parts separately, mounting them by tonguing-and-grooving and finally treating the prosthesis. Furthermore, the present invention also includes a dental prosthesis that comprises at least one dental piece (1) and a gum, where both are bonded by tonguing-and-grooving means.

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METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT

NºPublicación: EP4091578A1 23/11/2022

Solicitante:

TOKUYAMA DENTAL CORP [JP]

Resumen de: EP4091578A1

[Object] To provide a method of producing a plate denture using a stereolithography 3D printer, which is capable of producing a plate denture in a short time with a more simplified production process, the plate denture exhibiting excellent occlusion.[Solving Means] The problem is solved by a method of producing a plate denture, including: adhering an artificial tooth and a denture base photochemically solidified by a stereolithography 3D printer to each other by polymerizing an unpolymerized curable composition for stereolithography present on a surface of the denture base. Further, stronger adhesion between the artificial tooth and the denture base is achieved by mixing, in the curable composition for stereolithography, a polymerization initiator other than a photopolymerization initiator for stereolithography.

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NOVEL MULTI-ORGAN-CHIPS ESTABLISHING DIFFERENTIATION OF IPSC-DERIVED CELLS INTO ORGAN EQUIVALENTS

NºPublicación: EP4092108A1 23/11/2022

Solicitante:

TISSUSE GMBH [DE]

ES_2921049_T3

Resumen de: EP4092108A1

The present disclosure relates to novel multi-organ-chips establishing the differentiation of induced pluripotent stem cell (iPSC)-derived cells into organ equivalents on microfluidic devices and corresponding methods of generating organ equivalents. The present disclosure also relates to novel bioengineered tissue constructs mimicking organ barriers generated with iPSC-derived endothelial cells and/or organoids bioprinted in, and/or seeded on, a hydrogel. The present disclosure further relates to methods of bioengineering organ constructs comprising co-culturing iPSC-derived organ precursor cells and iPSC-derived fibroblasts and endothelial cells. The present disclosure specifically provides a microfluidic device comprising: (i) iPSC-derived hepatocyte precursor cells; (ii) iPSC-derived intestinal precursor cells; (iii) iPSC-derived renal tubular precursor cells; and (iv) iPSC-derived neuronal precursor cells; wherein the iPSC-derived precursor cells according to (i), (ii), (iii) and (iv) are differentiated from a single donor iPSC reprogrammed from a single type of somatic cell.

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一种用于椎间融合器的复合材料的制备方法

NºPublicación: CN115364277A 22/11/2022

Solicitante:

成都医学院第一附属医院

Resumen de: CN115364277A

本发明公开了一种用于椎间融合器的复合材料及其制备方法,包括:以磺化处理后的3D打印的聚醚醚酮peek为基底材料,通过修饰氧化石墨烯和聚多巴胺粘合成骨多肽,在3D打印的PEEK表面进行氧化石墨烯和成骨多肽的双重修饰制备新型3D打印氧化石墨烯/成骨多肽/磺化聚醚醚酮复合材料。本复合材料具有优秀的润湿性,具有良好的生物相容性和成骨性能,可为细胞和组织在材料表面黏附和生长奠定基础。

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EDIBLE AQUEOUS INKJET INK AND TABLET

NºPublicación: CN115380086A 22/11/2022

Solicitante:

凸版印刷株式会社

JP_2021167370_A

Resumen de: WO2021206067A1

The purpose of the present invention is to provide: an edible aqueous inkjet ink that contains a relatively large amount of a volatile alcohol, that has excellent transfer resistance, and that is capable of reducing occurrence of ink discharge malfunctions; and a tablet provided with a print portion printed by said inkjet ink. The edible aqueous inkjet ink according to an embodiment of the present invention contains an edible dye, ethanol, and a surfactant having an HLB value within the range of 16-20. The edible dye is preferably sodium copper chlorophyllin. Further, the surfactant is preferably a sucrose fatty acid ester.

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Stabilized hygienic trays

NºPublicación: US11505956B1 22/11/2022

Solicitante:

UNIVERSAL TECH CORP [US]

Resumen de: US11505956B1

Hygienic trays adapted to effectively restrain items under hygienic conditions are provided by equipping hygienic trays with an antipathogenic, cohesive and adhesive thermoset overlay provided in the form of an adhesive insert or tray coating. The overlay adhesively restrains emplaced items until manually removed from the overlay by the hygienic user while also providing an unexpected superior antipathogenic environment. The hygienic trays are particularly useful from hygienic applications wherein hygienic conditions and a need to stabilize trayed items against displacement are of a dominant concern. The tray may be of a simple platform design with or without a typical bordering rim which may be adapted for hand carriage or mounted onto another supportive structure.

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用于天然牙列的哥特式弓的固位装置

NºPublicación: CN217853401U 22/11/2022

Solicitante:

广州医科大学附属口腔医院(广州医科大学羊城医院)

Resumen de: CN217853401U

根据本实用新型实施例提出一种用于天然牙列的哥特式弓的固位装置,其包括:上颌固位夹板,其包括围绕上颌天然牙列形成的内侧和外侧,上颌固位夹板还包括由其内侧延伸出且位于同一水平面的多个固位连接部;下颌固位夹板,其包括围绕下颌天然牙列形成的内侧和外侧,下颌固位夹板还包括由其内侧延伸出且位于同一水平面的多个固位连接部;上颌哥特式弓,其具有多个固位钉,用于与上颌固位夹板的多个固位连接部连接,以确定上颌哥特式弓的位置;下颌哥特式弓,其具有多个固位钉,用于与下颌固位夹板的多个固位连接部连接,以确定下颌哥特式弓的位置。通过本实用新型能够在天然牙列上安装、固定及使用哥特式弓。

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APPARATUS, SYSTEM, METHOD OF POST-CURING AN ARTICLE, AND POST-CURED ARTICLE

NºPublicación: JP2022548851A 22/11/2022

Solicitante:

スリーエムイノベイティブプロパティズカンパニー

US_2022273409_PA

Resumen de: WO2021048733A1

The apparatus (1000) includes a housing (110), a chamber (120) disposed in the housing, at least two light emitting diodes (LEDs) (130) disposed within the housing (110), and a user interface (140) disposed on an exterior (112) of the housing. The chamber (120) is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber (120) includes a material transparent to actinic radiation and light from the LEDs (130) enters the chamber from more than one direction. The user interface (140) includes a display (142) and program switches (144) configured to adjust at least three operational parameters of the apparatus. The apparatus (1000) further includes a vacuum pump (150) operatively coupled to the chamber (120). The system includes the apparatus (1000) and an article (180). An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content. A method of post-curing an article includes obtaining an article (180), placing the article in an apparatus (1000), inputting a post-cure program or accessing a saved post-cure program through the user interface (140), and running the post-cure program. The post-cure program includes light intensity provided by a light source (130) and length of time of light provided by the light source (130), plus a delay time between initiation of light provided by the light source (130) and initiation of vacuum pulled by the vacuum pump (150) and/or a delay time between in

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一种3D打印手指牵伸支具的制作方法

NºPublicación: CN115363839A 22/11/2022

Solicitante:

上海交通大学医学院附属第九人民医院

Resumen de: CN115363839A

本发明提供了一种3D打印手指牵伸支具的制作方法,通过激光扫描技术获取手部三维参数,以网格形式输出,对网格模型进行后处理,导入正向三维建模软件进行设计,设计完成的支具模型最终通过3d打印技术快速成型。激光扫描和3d打印技术的结合不仅满足了个性化的需求,还使得支具的制作成本大为降低。3D打印手指牵伸支具的调节装置采用正反双向螺杆的设计,该力学传递装置的设计简单、高效,可实现双向无级调节。与此同时,垂直于手指的力臂杆设计,使得支具在调节过程中,牵伸力方向始终与关节面平行,可以有效避免不良应力对关节面的损害,符合生物力学的要求。

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MODELING DEVICES USED IN GUIDED BONE AND TISSUE REGENERATION

NºPublicación: JP2022548691A 21/11/2022

Solicitante:

オステオジェニクスバイオメディカル,インコーポレイテッド

CN_114667111_PA

Resumen de: US2021085471A1

This disclosure describes manufacturing of a device configured to guide bone and tissue regeneration for a bone defect. A method may include receiving a three-dimensional digital model or scan representing an anatomical feature to be repaired, generating a simulated membrane using the three-dimensional model, the simulated membrane being configured to cover the anatomical feature to be repaired, generating a digital two-dimensional flattened version of the simulated membrane, and generating code or instructions configured to cause a three-dimensional printer or milling device to produce a trimming guide that includes an opening corresponding to the flattened version of the simulated membrane and that further includes a cut-out configured to hold a premanufactured membrane. The trimming guide may be operative as a guide for marking or cutting the premanufactured membrane through the opening while the premanufactured membrane is held in the cut-out.

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THREE-DIMENSIONAL ORTHODONTIC RETAINER AND METHOD FOR PRODUCING A THREE-DIMENSIONAL ORTHODONTIC RETAINER

NºPublicación: DK3541317T3 21/11/2022

Solicitante:

HOSTETTLER JUERG [CH]
HOSTETTLER JONAS [CH]

US_2022031427_A1

Resumen de: WO2018092052A1

The invention relates to a three-dimensional orthodontic retainer (2) and to a method for producing such a retainer (2) in which the three-dimensional orthodontic retainer (2) is matched to the exact shape of the adjacent teeth (3) and is produced from a blank (1) in such a manner that the physical properties of the material of the remaining part of the blank (1) are unchanged in the retainer (2). The method for producing the three-dimensional orthodontic retainer (2) comprises the following method steps: creating a three-dimensional model of the structure of the patient's teeth (3); designing a customised, precisely fitting model of the retainer (2); producing the retainer (2) on the basis of the designed 3D model by computer-controlled deposition or application of material.

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一种数字化无牙颌角度复合基台导向导板

NºPublicación: CN217828117U 18/11/2022

Solicitante:

杭州口腔医院集团有限公司

Resumen de: CN217828117U

一种数字化无牙颌角度复合基台导向导板,涉及口腔种植技术领域,包括包括导向导板、设有固位孔和导向孔,导向导板的组织面形态与颌弓解剖形态一致,本实用新型采用数字化设计和3D打印技术成型,在实际种植流程中可直接利用种植导板建模数据进行后续设计,设计难度小的优点,角度复合基台导向开口的开口方向与基台定位器同向,开口直径略大于基台定位器直径,能精准定位无牙颌角度复合基台,角度复合基台定位可视开口,与角度复合基台导向开口相连续,便于在可视角度下实现角度复合基台与植体的精准连接,且不同于以往的金属导套设计,为3D打印树脂一体化导向导板,减少了多部件组分所带来的系统误差。

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一种用于保护颌面部穿刺模板3D打印设计方法

NºPublicación: CN115349930A 18/11/2022

Solicitante:

山东卓业医疗科技有限公司

Resumen de: CN115349930A

本发明公开了一种用于保护颌面部穿刺模板3D打印设计方法,具体包括以下步骤:S1、准备工作,S2、设计子板,S3、设计母板,S4、组合穿刺模板,本发明涉及医疗临床穿刺手术技术领域。该用于保护颌面部穿刺模板3D打印设计方法,病人经CT扫描确诊后,根据病情和治疗要求,在靶区内设计出主穿刺路径,自动生成三维数据模型,根据CT影像数据,勾画出母板区域并使之投影到病人体表,以贴合体表,设计定位基准十字交叉线以及定位基准柱,组合二个部分的设计为穿刺模板,可完全还原临床医生的设计意图,保证颌面部肿瘤微创穿刺手术的安全性和治疗效果,工作效率大幅度提升,成本大幅度降低,操作简单,维护方便。

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一种基于3D打印的辅助椎管内麻醉体外导板

NºPublicación: CN217828022U 18/11/2022

Solicitante:

陕西马克医疗科技有限公司

Resumen de: CN217828022U

本实用新型提供了一种基于3D打印的辅助椎管内麻醉体外导板,该体外导板包括皮肤贴合板,所述皮肤贴合板上侧设有导向柱,所述导向柱上端开设有针道,所述针道贯穿所述导向柱与皮肤贴合板。在制作导板时,首先采集病患医学数字成像数据,并利用医学数字成像数据建立人体三维数字模型a,然后利用人体三维数字模型a建立体外导板三维数字模型,并在体外导板三维数字模型上留出椎管内麻醉穿刺点的针道,最后利用体外导板三维数字模型制作体外导板。该制作方法可以对不同患者定制相应的体外导板,采用定制的体外导板在进行椎管内麻醉时可以对穿刺针进行精确导向,可靠性高,对医生的经验要求较低。

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3 Manufacturing method of bio-materials from animal tissue bio-materials from animal tissue manufactured thereby and 3D printing method using the same

NºPublicación: CN115361977A 18/11/2022

WO_2021206303_A1

Resumen de: KR102196026B1

The present invention relates to a method for producing a biological material derived from an animal tissue, a biological material derived from an animal tissue manufactured thereby, and a 3D printing method using the same, wherein the method includes: a decellularization step of removing cells from a tissue; a liquefaction step of liquefying the extracellular matrix of the decellularized tissue using an acidic protease; a filtration step of filtering a decellularized extracellular matrix solution obtained through the liquefaction step; and a sterilization step of sterilizing a mixture obtained through the filtration step. The biological material derived from an animal tissue has advantages of excellent biocompatibility and storage stability.

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TRANSPARENT, FRACTURE-RESISTANT POLYMERISATION RESINS FOR THE PRODUCTION OF DENTAL MOULDINGS

NºPublicación: JP2022173073A 17/11/2022

Solicitante:

イフォクレールヴィヴァデントアクチェンゲゼルシャフト

Resumen de: US2022370300A1

Radically polymerizable dental material, which contains at least one ABA or AB block copolymer, preferably at least one monofunctional, radically polymerizable monomer (a) and preferably at least one radically polymerizable urethane di(meth)acrylate telechel (b).

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GEL MICROSPHERE-BASED 3D PRINTING BIO-INK AND APPLICATION THEREOF

Nº publicación: WO2022237002A1 17/11/2022

Solicitante:

UNIV TSINGHUA [CN]

CN_113274554_A

Resumen de: WO2022237002A1

Disclosed are a gel microsphere-based 3D printing bio-ink and an application thereof. The 3D printing bio-ink is formed from cross-linked, cell-loaded gel microspheres, or is obtained by mixing cross-linked, cell-loaded gel microspheres with one or more non-crosslinked gel materials. The volume content of the cell-loaded gel microspheres in the 3D printing bio-ink is 40%-100%. The gel microsphere-based 3D printing bio-ink in the present invention has shear thinning and self-healing characteristics. Direct 3D printing of low-concentration or low-viscosity gel materials can be achieved without the addition of a rheology modifier. Therefore, the three-dimensional printing of a conventional gel material under ultra-low concentrations is achieved. Furthermore, hydrogel materials that are difficult to print can have excellent printability. By means of using gel microspheres as cell carriers, a customized microenvironment can be provided for activities such as cell growth, proliferation, and differentiation. Furthermore, cells can be protected from shear stress damage during the 3D printing process. The application of 3D bioprinting technology in complex tissue/organ construction is greatly facilitated.

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