3D BIOPRINTING

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Resultados 144 results. LastUpdate Updated on 06/12/2021 [05:11:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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RESTING ORTHOSIS FOR A JOINT

Publication No.: US2021369480A1 02/12/2021

Applicant:

MILLET INNOVATION [FR]

JP_2021508266_A

Absstract of: US2021369480A1

An orthosis for the support of a joint, adapted to the thumb or wrist, comprising: sleeve-like main member made of an elastic material, adapted to envelop the joint and distal and proximal limb portions on either side of the joint, elastically deformable panel housed in a pocket formed in the main member, and non-elastic bracing device for bracing the main member and a proximal portion of the panel around the proximal limb portion, the panel being configured such that, over at least 50% of the length of the main member along the limb portions, including a limb portion covered by the bracing device, the panel has a cross-section occupying more than 30% of the perimeter of the underlying limb, the panel having a stiffness defined by a Young's modulus between 5 and 10 MPa, while the material forming the main member has a stiffness of a lower order of magnitude.

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SYSTEMS AND METHODS FOR MANUFACTURING BIOSCAFFOLD EXTRACELLULAR STRUCTURES FOR TISSUE REGENERATION

Publication No.: US2021369463A1 02/12/2021

Applicant:

MENTOR WORLDWIDE LLC [US]

WO_2019217338_A1

Absstract of: US2021369463A1

A method of manufacturing a bioscaffold implant for a specific patient is provided. The method can comprise obtaining an image of a tissue section of the specific patient from imaging scans of the tissue section, wherein the tissue section includes a resected portion. The method can further comprise determining on the image of the tissue section a surface topography of the resected portion, determining an image of a bioscaffold implant that matches the surface topography of the resected portion, and manufacturing a bioscaffold implant with a surface portion that mirrors the surface topography of the resected portion.

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SYSTEMS AND METHODS FOR CUSTOM OBJECT DESIGN

Publication No.: US2021377508A1 02/12/2021

Applicant:

LANTOS TECH INC [US]

US_2020236341_A1

Absstract of: US2021377508A1

Systems and methods disclosed herein include a first scanner comprising an inflatable membrane configured to be inflated with a medium to conform an exterior surface of the inflatable membrane to an interior shape of a cavity, the medium attenuating, at a first rate per unit length, light having a first optical wavelength, and attenuating, at a second rate per unit length, light having a second optical wavelength; an emitter configured to illuminate an interior surface of the inflatable membrane; a detector configured to receive light from the interior surface; a processor configured to generate a first electronic representation of the interior shape based on the received light; and a design computer configured to modify the first electronic representation into a three-dimensional shape by correlating pixels of the first electronic representation with corresponding distance information from the first scanner to the inflatable membrane for each pixel.

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2D AND 3D BIOSCAFFOLD EXTRACELLULAR STRUCTURAL UNIT AND TISSUE STRUCTURE DESIGN AND METHODS OF MANUFACTURE

Publication No.: US2021369912A1 02/12/2021

Applicant:

MENTOR WORLDWIDE LLC [US]

CN_112384168_A

Absstract of: US2021369912A1

A bioscaffold structure is provided, the bioscaffold comprising a plurality of connected unit cells, each unit cell comprising a plurality of filaments composed of an extracellular material containing Collagen I and Collagen III, wherein each of the plurality of unit cells includes at least one opening connected to an internal volume.

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MODULAR BIOFABRICATION PLATFORM FOR DIVERSE TISSUE ENGINEERING APPLICATIONS AND RELATED METHOD THEREOF

Publication No.: US2021369917A1 02/12/2021

Applicant:

UNIV VIRGINIA PATENT FOUNDATION [US]

WO_2020072933_PA

Absstract of: US2021369917A1

System and method of bioprinting used to enable automated fabrication of various constructs with high reproducibility and scalability, while reducing costs and production timelines. The bioprinting applications provides a critical component to the further enrichment the overall biomanufacturing paradigm. The biofabrication of sheet-like implantable constructs and other construct types with cells deposited on both sides—a process that may be both scaffold and cell type agnostic, and furthermore, is amenable to many additional tissue engineering applications beyond skeletal muscle.

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Solid Forms and Methods of Preparing the Same

Publication No.: US2021369622A1 02/12/2021

Applicant:

UNIV CENTRAL LANCASHIRE [GB]

JP_2018533584_A

Absstract of: US2021369622A1

The present invention relates to a solid form, particularly to a 3D-printed immediate release solid dosage form (e.g. based on a pharmaceutical, nutraceutical, or food supplement composition). To overcome some of the solubility and disintegration problems inherited by 3D-printed solid dosage forms, the solid form comprises one or more channels, generally in the form of tubular passages or grooves, through the body of the solid form or the surface thereof.

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ORO-NASAL PATIENT INTERFACE FOR TREATING SLEEP DISORDERED BREATHING

Publication No.: US2021370005A1 02/12/2021

Applicant:

BESPOKE MEDICAL INNOVATIONS PTY LTD [AU]

AU_2019225444_A1

Absstract of: US2021370005A1

A patient interface (200, 300) comprising: a seal-forming structure (210, 220, 310, 320) including a face-engaging surface that is personalised to the patient's facial contour and to form a seal with the patient's face at least on or below the bridge of the patient's nose and between the patient's lower lip and on or above the patient's chin, preferably proximal to the patient's mentolabial crease, the face-engaging surface including at least one nare port (211, 311) shaped and sized to align with the patient's nares; an anterior surface (205, 305) including a connection port; wherein the seal-forming structure (210, 220, 310, 320) is non-deformable in response to headgear tension or pressurised air received within the seal-forming structure (210, 220, 310, 320).

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Renal Progenitor Cells

Publication No.: US2021371826A1 02/12/2021

Applicant:

UNIV QUEENSLAND [AU]

JP_2020031648_A

Absstract of: US2021371826A1

A method is provided for simultaneously producing both nephron progenitor cells and ureteric epithelial progenitor cells including the step of contacting intermediate mesoderm cells with: fibroblast growth factor 9 and/or fibroblast growth factor 20 and optionally, one or more selected from the group consisting of: bone morphogenic protein 7; heparin; a Wnt agonist; retinoic acid; and an RA antagonist. The concentrations of Wnt agonist, retinoic acid and/or RA antagonist may be manipulated to favour the relative production of nephron progenitor cells and ureteric epithelial progenitor cells. The intermediate mesoderm cells are ultimately derived from human pluripotent stem cells via a posterior primitive streak stage. The nephron progenitor cells and ureteric epithelial progenitor cells may have end uses such as for kidney repair and regeneration, bioprinting of kidneys and screening compounds for nephrotoxicity.

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PHOTOCURABLE RESIN FOR HIGH-RESOLUTION 3-D PRINTING

Publication No.: US2021371597A1 02/12/2021

Applicant:

THE UNITED STATES GOVENMENT AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS [US]

Absstract of: US2021371597A1

Provided are photocurable resins comprising a poly(siloxane)-based copolymer together with a photoinitiator, and other optional ingredients such as a photocurable diluent, a photoabsorber, a photosensitizer, or a hydrophillic additive. Also provided are methods of stereolithographically printing a 3-D object from a disclosed resin. Also provided is an improved method for stereolithographically printing a 3-D object, the improvement comprising the use of a disclosed photocurable resin. Further provided is a 3-D microfluidic device such as an artificial lung prepared from a disclosed photocurable resin.

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CUSTOMIZABLE SURGICAL BONE-CUTTING JIGSAW PUZZLE-TYPE GUIDE DEVICE AND CUSTOMIZABLE SURGICAL BONE-CUTTING GUIDE-TRACTION-SUCTION DEVICE

Publication No.: US2021369289A1 02/12/2021

Applicant:

CATHOLIC UNIV KOREA IND ACADEMIC COOPERATION FOUNDATION [KR]

US_2019388103_A1

Absstract of: US2021369289A1

Provided is a customizable surgical bone-cutting jigsaw puzzle-type guide device. The customizable surgical bone-cutting jigsaw puzzle-type guide device includes: a main guide portion that includes a main contact surface lengthily formed along a required main incision line of a bone to be cut and shaped to be brought into contact with the bone, and a main guide surface forming a guide line together with the main contact surface along the same line as the main incision line and shaped to be brought into contact with a cutting blade for guiding the movement of the cutting blade during cutting of the bone; and a connection portion extending from the main guide portion and connected to a side of the bone such that the main guide portion may be supported on the bone, the connection portion being configured to be detachably attached to the side of the bone.

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SYSTEMS FOR IMPROVING BLOOD CIRCULATION

Publication No.: US2021368910A1 02/12/2021

Applicant:

TINKER DESIGN LTD [GB]

KR_20210092209_A

Absstract of: US2021368910A1

A system for improving blood circulation, the system comprising a control unit comprising a processor and at least one article of footwear wherein one or more of the at least one articles of footwear together or alone comprise: one or more actuators coupled to and controlled by the control unit; one or more electrically-conductive paths; one or more sensors integrated into the at least one article of footwear and coupled to the processor, for providing measurement signals to the control unit; and the system further comprising an electrical power supply for supplying electrical power to the one or more sensors by means of the one or more electrically-conductive paths.

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DENTAL STENT

Publication No.: US2021369408A1 02/12/2021

Applicant:

SMILE FAST LTD [GB]

US_2021353385_A1

Absstract of: US2021369408A1

A dental stent for tooth restoration, comprising an acrylic outer shell and a set of metal matrix separator strips partially embedded into an inner silicon bed; a method of manufacturing a dental stent including 3D printing of a model wherein tooth forms of teeth to be restored are individually removable from a remainder of the model; a method of tooth restoration using a dental stent, and a kit of parts comprising a dental stent and a composite resin, and optionally a heater, a light cure unit, and a finishing tool kit.

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EDENTULOUS SURGICAL GUIDE

Publication No.: US2021369407A1 02/12/2021

Applicant:

IBUR LLC [US]

US_2019000590_A1

Absstract of: US2021369407A1

A dental surgical drill guide assembly and method includes a surgical guide housing and a base frame that fits to both gum tissue and one or multiple small areas of jawbone. The apparatus may be configured to accurately place dental implants according to planned positions. Such apparatus may increase the stability of the surgical guide by clasping and/or contacting the jawbone, while improving the overall fit and minimizing the need of invasive surgery and flapping by also clasping and/or contacting selected areas of the gum tissue at the same time. Self-locking alignment members aid in easy removal, and re-installation, of the surgical guide housing to the base frame.

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Methods for Direct Fabrication of Appliances for Palate Expansion

Publication No.: US2021369413A1 02/12/2021

Applicant:

ALIGN TECHNOLOGY INC [US]

CN_113143498_A

Absstract of: US2021369413A1

Systems, methods, and devices for producing appliances for expansion of the palate of a patient are provided. A palate expanding orthodontic appliance comprises a teeth engagement portion comprising a plurality of teeth engagement structures and a force generating portion coupled to the teeth engagement portion and configured to apply force to cause the patient's palate to expand. The orthodontic appliances can be designed according to the specifications provided herein and manufactured using direct fabrication methods.

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COLLAPSIBLE INNER FLOW CONTROL COMPONENT FOR SIDE-DELIVERABLE TRANSCATHETER HEART VALVE PROSTHESIS

Publication No.: EP3914192A1 01/12/2021

Applicant:

VDYNE INC [US]

ADDITIVELY MANUFACTURED MESH MATERIALS, WEARABLE AND IMPLANTABLE DEVICES, AND SYSTEMS AND METHODS FOR MANUFACTURING THE SAME

Publication No.: EP3914758A1 01/12/2021

Applicant:

MASSACHUSETTS INST TECHNOLOGY [US]

ADDITIVELY MANUFACTURED MESH MATERIALS, WEARABLE AND IMPLANTABLE DEVICES, AND SYSTEMS AND METHODS FOR MANUFACTURING THE SAME

Publication No.: EP3914758A1 01/12/2021

Applicant:

MASSACHUSETTS INST TECHNOLOGY [US]

COLLAPSIBLE INNER FLOW CONTROL COMPONENT FOR SIDE-DELIVERABLE TRANSCATHETER HEART VALVE PROSTHESIS

Publication No.: EP3914192A1 01/12/2021

Applicant:

VDYNE INC [US]

LIGHTED WEDGE TOOL

Publication No.: EP3914142A1 01/12/2021

Applicant:

EDGY TOOLS LLC [US]

LIGHTED WEDGE TOOL

Publication No.: EP3914142A1 01/12/2021

Applicant:

EDGY TOOLS LLC [US]

Absstract of: WO2020154438A1

A window wedge tool includes an elongated body having a cavity disposed within its proximal portion, the body having two vertical sides intersecting two force-applying surfaces with a tapered, curved profile to define a blade at a distal end of the body. At least one a light emitter within the body emits light from the distal portion. A power source is disposed within the cavity for providing power to the light emitter.

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高综合性能光固化生物3D打印复合水凝胶及其制备方法和应用

Publication No.: CN113713179A 30/11/2021

Applicant:

山东大学燕山大学

Absstract of: CN113713179A

本申请提供一种高综合性能光固化生物3D打印复合水凝胶及其制备方法和应用。所述高综合性能光固化生物3D打印复合水凝胶为以甲基丙烯酰化明胶、甲基丙烯酰化透明质酸、甲基丙烯酰化丝素蛋白为单体共价交联固化形成的聚合物凝胶,具有生物相容性高、成形性好、机械强度可调、快速凝胶化的优势,可用于制备脊髓支架,可在支架上接种神经细胞,或着进行载神经细胞打印,用于神经损伤的修复、神经药物的筛选等。本发明材料还可用于周围神经组织支架的打印,或者多孔复杂组织结构的打印。

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一种腹壁修复补片及其制备方法

Publication No.: CN113713168A 30/11/2021

Applicant:

上海大学

Absstract of: CN113713168A

本发明提供了一种腹壁修复补片及其制备方法,首先构建N个补片层的打印路径;配置有机相C;将细胞培养皿固定在电流体动力喷射打印装置的工作平台上,将所述有机相C倒入挤出头;利用所述电流体动力喷射打印装置将所述挤出头中的所述有机相C挤出,沉积在所述细胞培养皿中,并按照N个补片层的打印路径行走生成N个补片层,最终生成腹壁修复补片;本发明采用电流体动力喷射打印技术,通过改善腹壁修复补片的网状结构,制备一种具有良好柔韧性、生物相容性、与人体腹壁组织相似的各向异性以及增强腹壁修复补片的顶破性能,从而解决其在腹壁修复过程中力学性能不足的问题。

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一种光热固化的树脂组合物及其制备方法和应用

Publication No.: CN113717330A 30/11/2021

Applicant:

爱迪特(秦皇岛)科技股份有限公司

Absstract of: CN113717330A

本发明提供一种光热固化的树脂组合物及其制备方法和应用,所述树脂组合物包括特定份数的预聚物、单体、光引发剂、热引发剂、气相二氧化硅和玻璃粉的组合,通过添加特定份数的光引发剂搭配热引发剂,提高了固化反应的完成率,使所述树脂组合物固化更加充分,固化后的单体残留率更低;且还添加特定份数的气相二氧化硅和含钡玻璃粉作为填料,有效增强了所述树脂组合物的硬度、强度和耐磨性,使最终得到的树脂组合物经3D打印后得到的产品完全满足作为临时冠桥的要求。

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用于气管损伤修复的体内原位生物打印装置

Publication No.: CN113712609A 30/11/2021

Applicant:

清华大学

Absstract of: CN113712609A

本发明提供的用于气管损伤修复的体内原位生物打印装置,使用时,将物料输送管路与注射模块或管路模块连接。直线驱动机构位于体外,带动物料运输件和执行机构运动到气管内,使执行机构运动到待修复部位。根据气管修复部位的内径,通过第一旋转驱动组件调整执行机构的旋转角度,使打印针头的端部与修复部位的内壁紧密接触。在打印过程中,第二旋转驱动组件带动执行机构旋转,使打印针头的头端沿待修复气管的内壁周向旋转。同时,直线驱动机构带动执行机构沿待修复气管的轴向运动。在执行机构运动的过程中,物料输送管路向打印针头输送修复材料,通过打印针头使修复材料附着在气管内壁,完成在体内对气管进行修复的过程。

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METHOD FOR GENERATING DENTAL MODELS BASED ON AN OBJECTIVE FUNCTION

Nº publicación: CN113728363A 30/11/2021

Applicant:

3 \u5F62\u72B6\u80A1\u4EFD\u6709\u9650\u516C\u53F8

WO_2020161245_A1

Absstract of: WO2020161245A1

Disclosed is a computer-implemented method of generating a dental model based on an objective function output, comprising creating an objective function comprising at least one quality estimation function which trains at least one machine learning method that generates quality estimation output, and an objective function output is the output of the objective function providing a model as an input data to the objective function and generating model-related objective function output; and modifying the model based on the model-related objective function output to transform the model to a generated model, wherein the generated model is the dental model.

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