3D BIOPRINTING

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Resultados 190 results. LastUpdate Updated on 18/06/2021 [20:53:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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DECELLULARIZED BONE BIOMATERIAL ENRICHED WITH A HYDROGEL CONTAINING DECELLULARIZED EXTRACELLULAR BONE MATRIX

Publication No.: JP2021514820A 17/06/2021

Applicant:

ウニヴェルシダージフェデラウドエスピリトサント−ウエフェエエセUNIVERSIDADEFEDERALDOESPIRITOSANTO−UFES

KR_20210005562_A

Absstract of: WO2019161465A1

The invention relates to a biomaterial developed from decellularized animal bone tissue and coated with extracellular bone matrix in the form of a gel, which is capable of providing efficient mechanical and biological support and which furthermore allows enrichment with cell lines, nanocompounds or drugs, when used as a bone graft, bioreactor or vector in treatments, research and development of other biomaterials; that is to say, it has been developed from decellularized, lyophilized, porous, rigid bone material that can be manipulated and is safe and non-immunogenic, coated and enriched with substances that specifically stimulate bone tissue, presented/used in particulate form or as a block, and it thus has the capacity to promote the development of mature or progenitor cell lines in vitro when used as a bioreactor, and has a demonstrated capacity to integrate and accelerates cicatrization of fractures and infilling of bone defects when used as a graft in vivo; the biomaterial further allows the promotion of cell development, based on the fact that the integrity of the extracellular organic matrix of the bone tissue is maintained, and it is capable of improving cicatrization time, reducing costs and making a scientific contribution to basic research, demonstrating biotechnological importance, investigative need and the applicability of decellularized organic matrices to biomaterials.

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SPHERICAL TANTALUM POWDER, PRODUCTS CONTAINING THE SAME, AND METHODS OF MAKING THE SAME

Publication No.: JP2021515105A 17/06/2021

Applicant:

グローバルアドバンストメタルズユー.エス.エー.,インコーポレイティド

KR_20200125668_A

Absstract of: WO2020027874A2

Tantalum powder that is highly spherical is described. The tantalum powder can be useful in additive manufacturing and other uses. Methods to make the tantalum powder are further described as well as methods to utilize the tantalum powder in additive manufacturing processes. Resulting products and articles using the tantalum powder are further described.

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Piezoelectric Element, Piezoelectric Actuator, Ultrasonic Probe, Ultrasonic Apparatus, Electronic Apparatus, Liquid Jet Head, And Liquid Jet Apparatus

Publication No.: US2021184099A1 17/06/2021

Applicant:

SEIKO EPSON CORP [JP]

JP_2018164042_A

Absstract of: US2021184099A1

A piezoelectric element includes a first electrode layer, a piezoelectric layer, and a second electrode layer. The first electrode layer, the piezoelectric layer, and the second electrode layer are stacked in sequence on one another. The first electrode layer has a first part overlapping the piezoelectric layer in a plan view, and a second part at least partially separated from the first part and not overlapping the piezoelectric layer in the plan view. The second electrode layer has a third part overlapping the piezoelectric layer in the plan view, and a fourth part separated from the third part. The fourth part is in contact with the first part and the second part.

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Methods and Systems for Coherent Imaging and Feedback Control for Modification of Materials

Publication No.: US2021178513A1 17/06/2021

Applicant:

IPG PHOTONICS CORP [US]

US_2018290235_A1

Absstract of: US2021178513A1

Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light. A feedback controller controls at least one processing parameter of the material modification process based on an interferometry output generated using the imaging light. A method of processing interferograms is provided based on homodyne filtering. A method of generating a record of a material modification process using an interferometry output is provided.

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NANOCELLULOSE-CONTAINING BIOINKS FOR 3D BIOPRINTING, METHODS OF MAKING AND USING THE SAME, AND 3D BIOSTRUCTURES OBTAINED THEREFROM

Publication No.: JP2021514874A 17/06/2021

Applicant:

グランバイオインテレクチュアルプロパティホールディングス,エルエルシーレジニンクスリミテッド

CN_112533652_A

Absstract of: WO2019173637A1

Some variations of the invention provide a bioink composition for 3D bioprinting, comprising: nanocellulose in the form of nanocellulose crystals, nanocellulose fibrils, or preferably a combination thereof; alginate that is ionically crosslinkable in the presence of an ionic crosslinking agent; and water. The nanocellulose-alginate bioinks have favorable rheological, swelling, and biocompatibility properties for extrusion-based bioprinting. It is experimentally demonstrated that nanocellulose-alginate bioinks with human nasoseptal chondrocytes enable cartilage bioprinting at high resolution. The disclosed nanocellulose has been proven to be compatible with cell survival and proliferation; to possess nanoscale and microscale architectures mimicking the native extracellular environment, encouraging differentiation and tissue formation; and to have ideal rheological properties to allow extrusion 3D bioprinting. Bioink with a unique blend of crystal and fibril nanocellulose produces a very stable construct volume in culture.

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Prosthetic Partial Fingers

Publication No.: US2021177627A1 17/06/2021

Applicant:

UNIV COLORADO REGENTS [US]
POINT DESIGNS LLC [US]

WO_2020106728_A1

Absstract of: US2021177627A1

Various embodiments of the present invention generally relate to prosthetic partial finger designs that can mimic the last two joints of the finger. Some embodiments include a proximal phalange, a distal phalange coupled to the proximal phalange, and a knuckle track (e.g., formed in an arc). The knuckle track can be moveably coupled to the proximal phalange an may include multiple teeth formed on which the proximal phalange slides along. A ratcheting mechanism can contact the multiple teeth to allow sliding in only a first direction while the ratcheting mechanism is engaged. Some embodiments include a release mechanism (e.g., a button) configured to disengage the ratcheting mechanism from the multiple teeth to allow the distal phalange to slide in a second direction. In some embodiments, the device may include a spring-back capability that automatically extends the finger after reaching full finger flexion, enabling one-handed use.

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IMPLANT FOR BONE FRACTURE STABILIZATION

Publication No.: US2021177465A1 17/06/2021

Applicant:

UNIV SASKATCHEWAN [CA]

WO_2020037397_PA

Absstract of: US2021177465A1

Implants and methods for stabilizing bone fractures are provided. In one embodiment, the implants are spheres. In another embodiment, the implants are rods. The rods can be used to stabilize peripheral portions of a bone fracture. The rods can be shaped and configured to correspond to the shape of a region of bone against which the rod will be deployed. The rods can be provided with surface features for engaging adjacent rods and/or adjacent regions of bone to further stabilize the rods. The spheres can be inserted to fill a remaining volume of the fracture cavity. The implants can be made from orthobiologic materials.

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FOOTWEAR MIDSOLE WITH WARPED LATTICE STRUCTURE AND METHOD OF MAKING THE SAME

Publication No.: US2021177093A1 17/06/2021

Applicant:

ADIDAS AG [DE]

CN_112890370_A

Absstract of: US2021177093A1

A midsole for an article of footwear including a three-dimensional mesh including interconnected unit cells and methods of making the same. The interconnected unit cells each include a plurality of struts defining a three-dimensional shape. The interconnected unit cells are connected at nodes having a valence number defined by the number of struts connected at that node. The valence number of the nodes may vary to provide customized characteristics to zones or portions of the midsole. The plurality of interconnected unit cells may be organized in a warped cubic lattice structure. The warped cubic lattice structure and the size/shape of interconnected unit cells may vary to provide customized characteristics to zones or portions of the midsole. The three-dimensional mesh may be customized based on a biometric data profile for an individual, or group of individuals. The midsole may be manufactured using an additive manufacturing process.

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INTRAORAL SCANNING WITH RAW DEPTH DATA

Publication No.: US2021177266A1 17/06/2021

Applicant:

TEUFEL CLAYTON ADAMS [US]

Absstract of: US2021177266A1

The following relates generally to production of dental products. More particularly, techniques are disclosed for generating a 3D model of a patient's mouth, which may be used to produce dental products. In some embodiments, an infrared scanner is used to generate the raw depth information of a patients mouth. The produced dental product may include any of dental dentures, implants, teeth, aligners, crowns, veneers, partials, relines, mouthguards, retainers, etc.

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ATTACHMENTS FOR HANDLING AND TRACKING FABRICATED CUSTOM OBJECTS

Publication No.: US2021178639A1 17/06/2021

Applicant:

ALIGN TECHNOLOGY INC [US]

Absstract of: US2021178639A1

Embodiments relate to a pre-fabricated attachment for fabricating custom objects. In one embodiment, a system includes a mold and a pre-fabricated attachment. The mold includes a physical model of a dental arch of a patient and one or more first features. An orthodontic aligner is to be formed over the physical model. The pre-fabricated attachment includes one or more second features configured to removably attach to the one or more first features. The pre-fabricated attachment further includes a traceability component configured to be used to determine one or more identifiers corresponding to the mold. The pre-fabricated attachment further includes a handling component configured to be secured by a robot or person to transport the mold and pre-fabricated attachment during production of the orthodontic aligner. The pre-fabricated attachment may be reused.

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FABRICATION OF POROUS SCAFFOLDS USING ADDITIVE MANUFACTURING WITH POTENTIAL APPLICATIONS IN BONE TISSUE ENGINEERING

Publication No.: EP3833498A1 16/06/2021

Applicant:

OHIO STATE INNOVATION FOUNDATION [US]

WO_2020033607_A1

Absstract of: WO2020033607A1

The present disclosure describes additive manufacturing methods, in particular methods for optimizing the manufacture of objects by three-dimensional printing processes. Also provided are bioreactors as well as methods of using thereof.

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METHOD AND DEVICE FOR PROVIDING OR ABSORBING A SCENT

Publication No.: EP3835029A1 16/06/2021

Applicant:

BAYERISCHE MOTOREN WERKE AG [DE]

Absstract of: EP3835029A1

Disclosed is a method, comprising the steps:- forming a matrix by an additive manufacturing process;- providing a scent material and/or an absorber material to the matrix during and/or after the additive manufacturing process.

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ALIGNER DAMAGE PREDICTION AND MITIGATION

Publication No.: EP3833295A1 16/06/2021

Applicant:

ALIGN TECHNOLOGY INC [US]

AU_2019346652_A1

Absstract of: WO2020069446A1

Embodiments relate to an aligner breakage solution. A method includes obtaining a digital design of a polymeric aligner for a dental arch of a patient. The polymeric aligner is shaped to apply forces to teeth of the dental arch. The method also includes performing an analysis on the digital design of the polymeric aligner using at least one of a) a trained machine learning model, b) a numerical simulation, c) a geometry evaluator or d) a rules engine. The method may also include determining, based on the analysis, whether the digital design of the polymeric aligner includes probable points of damage, wherein for a probable point of damage there is a threshold probability that breakage, deformation, or warpage will occur. The method may also include, responsive to determining that the digital design of the polymeric aligner comprises probable points of damage, performing corrective actions based on the probable points of damage.

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PLATELET LYSATE COMPOSITIONS AND USES THEREOF

Publication No.: EP3833379A1 16/06/2021

Applicant:

IFIX MEDICAL PTY LTD [AU]

CN_112912101_A

Absstract of: WO2020028944A1

The present invention relates to compositions, kits, and methods for providing mechanical support and/or agents to biological targets. Specifically, the compositions comprise platelet lysate, fibrinogen and thrombin. The compositions can be used for the treatment of wounds/injuries (e.g. corneal), and for other applications including tissue culture.

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一种抗扰动高精度的金属义齿3D打印装置

Publication No.: CN213437193U 15/06/2021

Applicant:

合肥一凡义齿有限公司

Absstract of: CN213437193U

本实用新型公开了一种抗扰动高精度的金属义齿3D打印装置,包括3D打印机本体,所述3D打印机本体内壁顶端两侧分别固定连接有第一导轨,且第一导轨表面滑动连接有第一连接块,所述两个第一连接块之间固定连接有第二导轨,且第二导轨表面滑动连接有第二连接块,所述第二连接块底端固定安装有打印头。本实用新型中,通过液压杆可以带动着工作台升降移动,能够配合高度固定的打印头进行3D打印作业,在升降的过程中,托板通过两侧的滑块在滑槽内滑动,使其升降过程更为稳定,配合托板与工作台之间的多个缓震弹簧,可以缓解工作台的振动感,使其工作台升降更为稳定,防止工作台抖动,造成顶端建模打印出现偏差位移,提高打印精度。

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组织补偿膜的生成方法和组织补偿膜

Publication No.: CN112957619A 15/06/2021

Applicant:

苏州普能医疗科技有限公司

Absstract of: CN112957619A

本发明提供一种组织补偿膜的生成方法和组织补偿膜,该组织补偿膜的生成方法包括如下步骤:S1:基于患者影像信息,获得初始的组织补偿膜;S2:对当前获得的组织补偿膜进行剂量分布优化,以获得最优的计划剂量分布;S3:基于所述计划剂量分布对当前获得的组织补偿膜进行调整,获得调整后的组织补偿膜;S4:执行步骤S2,并判断剂量分布结果是否满足处方要求,若满足则跳转至步骤S5,否则继续执行步骤S3;S5:生成组织补偿膜。本发明通过采用客观的优化算法和客观的评价指标,替代人工的经验,从而能够根据具体病例生成更好的组织补偿物形状,进而提高患者的临床受益。

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一种带有牵引附件的隐形牙套

Publication No.: CN213430681U 15/06/2021

Applicant:

深圳爱舒笑科技有限公司

Absstract of: CN213430681U

本发明公开了一种带有牵引附件的隐形牙套,包括隐形牙套本体还包括一动力绳,所述牙套本体设置有局部凸起,凸起底部设置有切割光滑的豁口,所述动力绳一端通过所述豁口固定,另一端可以固定在另一处牵引附件上或挂在种植钉,舌侧扣以及托槽上。通过牙套本体和动力绳的结合,可以实现360度无死角牵引,从而为隐形矫正提供了更多可能,如:推磨牙向后,牵引埋伏牙等。

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基于丝素蛋白的取向性生物墨水及其制备方法和应用

Publication No.: CN112957526A 15/06/2021

Applicant:

苏州大学

Absstract of: CN112957526A

本发明涉及一种基于丝素蛋白的取向性生物墨水及其制备方法和应用。本发明利用具有电、磁响应性的纳米纤维的电、磁响应性在电场或磁场作用下形成纤维取向结构,制备出适用于多种类型的3D打印机的取向性生物墨水,可构建纳米‑微米‑宏观的多级高取向度仿生结构。

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Artificial blood vessel printer

Publication No.: CN112932731A 11/06/2021

Applicant:

广州帷幄生物科技有限公司

CN_112120829_A

Absstract of: CN112120829A

The invention relates to an artificial blood vessel printer. The artificial blood vessel printer comprises a workbench, spray nozzle apparatus used for spraying different materials, and blood vessel winding apparatus used for making the different materials sprayed by the spray nozzle apparatus into a blood vessel, wherein a base, and a high-voltage power supply for applying high-voltage static electricity are arranged in the workbench, a support frame, and first driving apparatus for driving the blood vessel winding apparatus to rotate are arranged on the base, the first driving apparatus is fixedly connected with the blood vessel winding apparatus, the support frame is connected with the spray nozzle apparatus in a sliding manner, and adjusting apparatus for adjusting a diameter of the blood vessel is arranged on the blood vessel winding apparatus. According to the artificial blood vessel printer, composite materials with different components are sprayed to the blood vessel winding apparatus with the blood vessel diameter adjusting function through the spray nozzle apparatus, and the high-voltage static electricity is applied through the high-voltage power supply during spraying to enable the composite materials to be cured instantly, so that the blood vessel prepared through the printer has the advantages of high elasticity, high toughness, high strength and the like.

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一种3D打印子宫托的方法

Publication No.: CN112939560A 11/06/2021

Applicant:

王丽

Absstract of: CN112939560A

本发明公开了一种3D打印子宫托的方法,属于医疗技术领域,包括如下步骤:S1、尺寸设计;S2、模型图设计;S3、打印处理;S4、注塑制备。本发明提供了一种3D打印子宫托的方法,此方法简单,能够为患者打印制造适合自己的子宫托产品,满足了定制、针对性治疗的需求,且此方式打印制得的子宫托具有强度高、生物相容性好、耐温耐腐等优点,大大提升了子宫托的使用寿命和安全性,极具市场竞争力和推广应用价值。

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可摘义齿基牙预备与种植体植入用联合导板及其制作方法

Publication No.: CN112932706A 11/06/2021

Applicant:

中国人民解放军空军军医大学

Absstract of: CN112932706A

本发明公开一种可摘义齿基牙预备与种植体植入用联合导板及其制作方法,制作步骤包括:制取牙列及牙槽嵴模型,后对牙列、牙槽嵴模型以及牙列口内进行数字化扫描,获得数字化模型;将数字化模型与患者拍摄的CBCT三维重建牙槽骨模型进行匹配,获得可摘义齿基托三维模型;对可摘义齿基托三维模型进行可摘义齿就位道分析确定,后制作基牙孔、可摘义齿基牙预备导杆以及种植体植入导环,获得联合导板三维模型;将联合导板三维模型通过计算机生成,并进行3D树脂打印,即可获得可摘义齿基牙预备与种植体植入用联合导板。本发明制得的联合导板在使用过程中具有减小种植体部件间磨损、RPD顺利被动就位和取出、减缓边缘牙槽嵴吸收,保证种植体使用寿命的优点。

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METHOD FOR MANUFACTURING SKIN REGENERATION SHEET CUSTOMIZED FOR PATIENT WITH DIABETIC FOOT DISEASE, AND SKIN REGENERATION SHEET CUSTOMIZED FOR PATIENT WITH DIABETIC FOOT DISEASE, MANUFACTURED THEREBY

Publication No.: CN112955193A 11/06/2021

Applicant:

罗基医疗保健公司

AU_2019382300_A1

Absstract of: EP3831420A1

The specification relates to a method of manufacturing a diabetic foot patient-specific skin regeneration sheet, and a diabetic foot patient-specific skin regeneration sheet.

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基于牙齿多个位置重叠模型生产的无托槽隐形矫治器及其制作方法

Publication No.: CN112932698A 11/06/2021

Applicant:

舒广

Absstract of: CN112932698A

本发明提供一种基于牙齿多个设计位置重叠的牙模生产的无托槽隐形矫治器及其制作方法,属于正畸技术中隐形矫治器领域。所述矫治器包括牙模和覆盖在牙模表面上并与之匹配的牙套。获得患者的数字化牙颌模型后,允许一颗或多颗牙齿包含多个设计位置的重叠,通过模型布尔运算获得重叠体,在重叠体牙模上直接打印牙套或间接热压模成型获得牙套。本发明的隐形矫治器和传统隐形矫治器相比,牙套在某些牙齿面、颊舌面或近远中面存在一定的空隙,牙套具有更多变化外形,有利于牙齿移动的导航或调节矫治力大小进行有效的支抗管理,从而提高隐形牙套的矫治效率;还可以导引牙齿萌出建,通过牙齿的锁结调整颌间关系,具备一定的生长改良效果。

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基于关键点控制的虚拟模型成型装置及方法

Publication No.: CN112932732A 11/06/2021

Applicant:

武汉市中心医院

Absstract of: CN112932732A

本发明提供一种基于关键点控制的虚拟模型成型装置及方法,包括工作台,工作台上设有十字滑台机构,十字滑台机构上连接有直线电机,直线电机包括可上下滑动的点压棒,直线电机下方设有第一阵列针板,第一阵列针板包括多个可上下滑动的细针柱,点压棒用于下压细针柱,点压棒直径小于相邻细针柱的最小中心距;利用数字化技术,将虚拟模型快速转化为现实模型,提高医生参与度,便于直观确认主动脉支架体外开窗位置;提取主动脉虚拟模型数据的关键点,利用多层针板装置,通过三轴机构按压上层针柱,通过过渡的柔性薄板拟合模型曲面,极大减少按压次数,提高成型效率。

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一种用于义齿加工快速清洁3d打印装置

Nº publicación: CN213412948U 11/06/2021

Applicant:

深圳市美鸣齿科技术有限公司

Absstract of: CN213412948U

本实用新型公开了一种用于义齿加工快速清洁3d打印装置,包括主体和操作台,所述主体的内壁左右端顶部安装有高压喷气组件,且高压喷气组件的外壁开设有喷头,所述操作台固定于主体的底部,且操作台的顶部从内到外依次安装有升降组件、弹簧和气缸,所述升降组件的外壁焊接有防护框架,且升降组件的中部旋接有打印模块,所述弹簧的顶部固定有操作板,且操作板的左右端顶部设置有限位板,所述主体的顶端外壁安装有连接轴。该用于义齿加工快速清洁3d打印装置设置将喷头置于高压喷气组件的外壁,利用高压喷气组件的设置,使得气体通过喷头喷出,从而实现对主体内部灰尘的清洁作用,代替了常规的水洗清洁,有利于保证该打印装置的正常使用。

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