TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 90 resultados LastUpdate Última actualización 03/12/2021 [10:32:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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ELECTRONIC DEVICE, ELECTRONIC DEVICE CONTROL METHOD, AND ELECTRONIC DEVICE CONTROL PROGRAM

NºPublicación: EP3915468A1 01/12/2021

Solicitante:

KYOCERA CORP [JP]

CN_113329686_A

Resumen de: EP3915468A1

An electronic device includes a compression portion, a pressure regulation unit, a pressure sensor, and a control unit. The compression portion compresses a target region of a subject. The pressure regulation unit regulates an internal pressure of the compression portion. The pressure sensor detects the internal pressure of the compression portion. The control unit estimates a state of glucose metabolism or lipid metabolism of the subject on the basis of the internal pressure of the compression portion detected by the pressure sensor in a period during which the pressure regulation unit changes the internal pressure of the compression portion.

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PORTABLE DEVICE AND METHOD FOR NON-INVASIVE BLOOD GLUCOSE LEVEL ESTIMATION

NºPublicación: EP3916376A1 01/12/2021

Solicitante:

UNIV SEVILLA [ES]

CN_113692530_A

Resumen de: EP3916376A1

The invention relates to a device (1) comprising a measuring unit (2) with a measuring module (4) for measuring the glucose level, a first computer module (5) for processing data from a first part of the process for measuring the glucose level, a first communications module (6), a first data storage module (7) and a pushbutton (8). The device also comprises a personal monitoring unit (3) with second and third communication modules (17, 20), a second computer module (18) for processing data from a second part of the process for measuring the glucose level, an interface module (19) and a second data storage module (22). Also described is a method for non-invasive blood glucose level estimation.

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BODY ATTACHABLE UNIT FOR CONTINUOUS BLOOD GLUCOSE MEASUREMENT

NºPublicación: US2021361197A1 25/11/2021

Solicitante:

I SENS INC [KR]

AU_2019347534_A1

Resumen de: US2021361197A1

The present disclosure relates to a body-attachable unit for continuously measuring blood glucose. As the body-attachable unit is manufactured to be assembled in an applicator, additional effort is minimized such that the body-attachable unit can be attached to the body by simply operating the applicator. In particular, since the body-attachable unit is provided with a wireless communication chip such that communication with an external terminal is possible, the body-attachable unit can be used simply and conveniently without additional work of connecting a separate transmitter, and thus can be maintained more easily. In addition, since the body-attachable unit is operated by an operation of a user after being attached to the body, the start time of the operation can be adjusted to an appropriate time according to the needs of the user. Accordingly, the body-attachable unit can be operated in a stabilized state, thereby allowing for more accurate blood glucose measurement.

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ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS

NºPublicación: US2021361205A1 25/11/2021

Solicitante:

DEXCOM INC [US]

JP_2021164475_A

Resumen de: US2021361205A1

Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.

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MANAGEMENT OF INSUFFICIENT HYPOGLYCEMIA RESPONSE

NºPublicación: US2021361866A1 25/11/2021

Solicitante:

MEDTRONIC MINIMED INC [US]

CN_109891510_A

Resumen de: US2021361866A1

A system includes one or more processors and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of obtaining an insulin-on-board (IOB) value, wherein the IOB value is a quantity of insulin remaining in a patient following delivery of a bolus of insulin, scaling a total daily dose (TDD) value by a factor, to generate a result having a value that is less than the TDD value, based on determining that the IOB value is greater than the result, identifying a condition in which the patient's glucose level will continue to decrease after suspension of basal insulin dosage delivery, and responsive to identifying the condition, causing performance of an action for preventing the patient's glucose level from falling into a hypoglycemic range in combination with the suspension of basal insulin dosage delivery.

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GIGAHERTZ FREQUENCY FRINGING NEAR-FIELD BIOMEDICAL SENSOR

NºPublicación: US2021361180A1 25/11/2021

Solicitante:

CHIEN JUN CHAU [US]
CHEN STANLEY YUANSHIH [US]

Resumen de: US2021361180A1

A near-field sensor method and device for obtaining biomedical information is disclosed. A transmission-line aperture arrangement configured to guide electromagnetic waves and emit near-field fringing energy, is placed near the skin. The transmission line is excited at a narrow-band Gigahertz frequency. The near-field fringing energy emitted by the sensor device penetrates at least partially into the skin and underlying blood vessels, and this energy is partially absorbed and partially phase shifted in a time varying manner according to the changes in tissue physiology. The status of the sensor device is monitored over a plurality of time intervals, and changes in both the phase and the amplitude of the signals passing though the transmission line are used to determine biomedical information such as heart rates, PTT, blood pressure, and glucose levels. Various transmission-line configurations, and various reference transmission-line methods to reduce low-frequency noise, are also discussed.

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SYSTEMS, DEVICES, AND METHODS FOR ANALYTE MONITORING AND BENEFITS THEREOF

NºPublicación: US2021366609A1 25/11/2021

Solicitante:

ABBOTT DIABETES CARE INC [US]

Resumen de: US2021366609A1

A method of treatment of a type 2 diabetic patient includes selecting a type 2 diabetic patient having a predetermined comorbidity for treatment, initiating a continuous glucose monitor regimen for the selected type 2 diabetic patient, wherein after six months of initiation of the continuous glucose monitor regimen, a rate of hospitalization for a predetermined diagnostic category of the selected patient having the predetermined comorbidity is reduced by at least 12% relative to an average rate of hospitalization for the predetermined diagnostic category of selected patients having the predetermined comorbidity without the continuous glucose monitor regimen.

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HOSPITAL MANAGEMENT SYSTEM AND THE CONTROL METHOD THEREOF

NºPublicación: US2021366260A1 25/11/2021

Solicitante:

INFOMINING CO LTD [KR]

KR_102251599_B1

Resumen de: US2021366260A1

Disclosed is a hospital management system including a communication unit for transmitting and receiving data, a memory for storing at least one instruction, and at least one processor for executing the at least one instruction stored in the memory. The at least one processor controls the communication unit to receive biometrics of a patient in real time, determines a disease symptom variation of the patient based on an examination result and the biometrics, wherein the examination result includes at least one of CT, Xray, MRI results, a body temperature, a pulse, a blood pressure, an oxygen saturation, an electrocardiogram, or a blood sugar level of the patient, controls the communication unit to transmit at least one of the examination result, the biometrics, or the disease symptom variation to a hospital electronic medical record system and a medical staff device, and receives prescription information from a medical staff, and performs prescription corresponding to the prescription information for the patient.

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SYSTEMS, DEVICES, AND METHODS OF ANALYTE MONITORING

NºPublicación: US2021361199A1 25/11/2021

Solicitante:

ABBOTT DIABETES CARE INC [US]

Resumen de: US2021361199A1

A glucose monitoring system includes a sensor control device comprising an analyte sensor coupled with sensor electronics, the sensor control device configured to transmit data indicative of an analyte level, and a reader device comprising a wireless communication circuitry configured to receive the data indicative of the analyte level, and one or more processors coupled with a memory. The memory is configured to store instructions that, when executed by the one or more processors, cause the one or more processors to: determine a frequency of interaction over a first time period based on one or more instances of user operation of the reader device, and output a first notification if the determined frequency of interaction is below a predetermined target level of interaction and output a second notification if the determined frequency of interaction is above the predetermined target level of interaction, wherein below the predetermined target level of interaction, an increase in the determined frequency of interaction corresponds to a first improvement in a metabolic parameter, and above the predetermined target level of interaction, an increase in the determined frequency of interaction corresponds to a second improvement in the metabolic parameter.

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METHODS OF WIRELESS COMMUNICATION IN AN INFUSION PUMP SYSTEM

NºPublicación: US2021368442A1 25/11/2021

Solicitante:

TANDEM DIABETES CARE INC [US]

US_2020329433_A1

Resumen de: US2021368442A1

Disclosed herein are methods for establishing communication protocols between wireless devices in infusion pump systems. Infusion pump systems can include a number of components capable of wireless communication with one or more other components including an infusion pump, a continuous glucose monitoring (CGM) system, a smartphone or other multi-purpose consumer electronic device and/or a dedicated remote controller for the infusion pump. Communications among these devices can be coordinated to increase efficiency and conserve battery power.

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CONFIGURABLE TARGET GLUCOSE VALUES

NºPublicación: US2021361864A1 25/11/2021

Solicitante:

MEDTRONIC MINIMED INC [US]

CA_3110084_PA

Resumen de: US2021361864A1

A system includes one or more processors and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of obtaining a first target value for a glucose level of a patient, modifying a glucose setpoint from a second target value to the first target value, and regulating the glucose level of the patient to the modified glucose setpoint based on controlling insulin delivery by an insulin infusion device.

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INTEGRATED CLOSED-LOOP MEDICATION DELIVERY WITH ERROR MODEL AND SAFETY CHECK

NºPublicación: US2021361867A1 25/11/2021

Solicitante:

ABBOTT DIABETES CARE INC [US]
CAMBRIDGE ENTPR LTD [GB]

US_2019151540_A1

Resumen de: US2021361867A1

A closed-loop system for insulin infusion overnight uses a model predictive control algorithm (“MPC”). Used with the MPC is a glucose measurement error model which was derived from actual glucose sensor error data. That sensor error data included both a sensor artifacts component, including dropouts, and a persistent error component, including calibration error, all of which was obtained experimentally from living subjects. The MPC algorithm advised on insulin infusion every fifteen minutes. Sensor glucose input to the MPC was obtained by combining model-calculated, noise-free interstitial glucose with experimentally-derived transient and persistent sensor artifacts associated with the FreeStyle Navigator® Continuous Glucose Monitor System (“FSN”). The incidence of severe and significant hypoglycemia reduced 2300- and 200-fold, respectively, during simulated overnight closed-loop control with the MPC algorithm using the glucose measurement error model suggesting that the continuous glucose monitoring technologies facilitate safe closed-loop insulin delivery.

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TRANSCUTANEOUS ANALYTE SENSOR

NºPublicación: US2021361198A1 25/11/2021

Solicitante:

DEXCOM INC [US]

US_2021321914_A1

Resumen de: US2021361198A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

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INTEGRATED ARTIFICIAL PANCREAS WITH MULTIPLE INFUSION MODES

NºPublicación: WO2021228270A1 18/11/2021

Solicitante:

MEDTRUM TECH INC [CN]

CN_113117181_A

Resumen de: WO2021228270A1

An integrated artificial pancreas with multiple infusion modes, comprising: drug infusion unit (110); program unit (120) comprising input end (121) and output end (122), and the input end (121) comprises a plurality of electrically connective regions (121a、121b) for receiving signals of analyte data in the body fluid, after the output end (122) is electrically connected to the power unit, the program unit (120) controls whether the drug infusion unit (110) delivers drugs; and an infusion cannula (130) provided with at least two detecting electrodes, the infusion cannula (130) is the drug infusion channel, the electrodes are disposed on the cannula wall. It takes only one insertion to perform both analyte detection and drug infusion.

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BILATERALLY DRIVEN CLOSED-LOOP ARTIFICIAL PANCREAS

NºPublicación: WO2021227297A1 18/11/2021

Solicitante:

MEDTRUM TECH INC [CN]

WO_2021228232_A1

Resumen de: WO2021227297A1

A bilaterally driven closed-loop artificial pancreas, comprising: a detection module (100); an infusion module (102), including: a drug storage unit (1150); a screw (1170) and a driving wheel (1130) provided with wheel teeth, the driving wheel (1130) drives the screw (1170) and the screw (1170) pushes a piston (1160); a driving unit (1100) cooperating with the driving wheel (1130), the driving unit (1100) includes at least two driving portions (1110); a power unit (1180) connected to the driving unit (1100), the power unit (1180) outputs two forces in two directions on the driving unit (1100); and a program module (101) imported the total daily dose algorithm and the current insulin infusion algorithm. The artificial pancreas can accurately calculate the TDD value and the current insulin infusion dose, and enhance user experience.

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ENZYME IMMOBILIZED ADHESIVE LAYER FOR ANALYTE SENSORS

NºPublicación: US2021356420A1 18/11/2021

Solicitante:

DEXCOM INC [US]

AU_2021257924_A1

Resumen de: US2021356420A1

Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

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METHOD AND SYSTEM FOR NON-INVASIVE OPTICAL BLOOD GLUCOSE DETECTION UTILIZING SPECTRAL DATA ANALYSIS

NºPublicación: US2021353186A1 18/11/2021

Solicitante:

ST LOUIS MEDICAL DEVICES INC [US]

US_2021228117_A1

Resumen de: US2021353186A1

Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, receiving the output signal from the at least one light detector with a processor and based on the received output signal, calculating the attenuance attributable to blood in a sample with a signal-to-noise ratio of at least 20-to-1; and determining a blood glucose level.

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LOW OXYGEN IN VIVO ANALYTE SENSOR

NºPublicación: US2021353187A1 18/11/2021

Solicitante:

DEXCOM INC [US]

US_2019183396_A1

Resumen de: US2021353187A1

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

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TUNABLE HYBRID III-V/ IV LASER SENSOR SYSTEM-ON-A-CHIP FOR REAL-TIME MONITORING OF A BLOOD CONSTITUENT CONCENTRATION LEVEL

NºPublicación: US2021353183A1 18/11/2021

Solicitante:

BROLIS SENSOR TECH UAB [LT]
UNIV GENT [BE]
IMEC VZW [BE]

JP_2020520768_A

Resumen de: US2021353183A1

A spectroscopic laser sensor based on hybrid III-V/IV system-on-a-chip technology. The laser sensor is configured to either (i) be used with a fiber-optic probe connected to an intravenous/intra-arterial optical catheter for direct invasive blood analyte concentration level measurement or (ii) be used to measure blood analyte concentration level non-invasively through an optical interface attached, e.g., to the skin or fingernail bed of a human. The sensor includes a III-V gain-chip, e.g., an AlGaInAsSb/GaSb based gain-chip and a photonic integrated circuit, with laser wavelength filtering, laser wavelength tuning, laser wavelength monitoring, laser signal monitoring and signal output sections realized on a chip by combining IV-based semiconductor substrates and flip-chip AlGaInAsSb/GaSb based photodetectors and embedded electronics for signal processing. Embodiments of the invention may be applied for real-time monitoring of critical blood analyte concentration levels such as lactates, urea, glucose, ammonia, albumin, etc.

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SYSTEMS AND METHODS FOR AUTOMATED INSULIN DELIVERY RESPONSE TO MEAL ANNOUNCEMENTS

NºPublicación: US2021353857A1 18/11/2021

Solicitante:

TANDEM DIABETES CARE INC [US]

Resumen de: US2021353857A1

Disclosed herein are apparatuses and methods that account for meal announcements in closed loop insulin delivery systems. Rather than simply increasing an insulin delivery rate in response to the meal announcement, the closed loop algorithm can be modified to increase the insulin on board tolerance during eating periods. This approach utilizes the stability of the cascaded loop in the closed loop algorithm to prevent the oscillations in glucose levels that can occur by simply increasing the basal rate.

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USER INTERFACE FOR DIABETES MANAGEMENT SYSTEMS AND DEVICES

NºPublicación: US2021353858A1 18/11/2021

Solicitante:

BIGFOOT BIOMEDICAL INC [US]

US_2019175833_PA

Resumen de: US2021353858A1

One or more embodiments of the disclosure relate, generally, to a diabetes management system. The diabetes management system may include a computing device that is configured to receive data relating to prior insulin use of a user and calculate a sliding scale glucose correction based, at least in part, on the data relating to prior insulin use.

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SYSTEM AND METHOD FOR DUAL MODEL-BASED EARLY PREDICTION OF HEART DISEASE FOR INDIAN TYPE-2 DIABETES MELLITUS PATIENTS

NºPublicación: AU2021105334A4 18/11/2021

Solicitante:

AHMAD JAMAL [IN]
AHMED AQUIL [IN]
KHAN YUSUFI FAIZ NOOR [IN]

Resumen de: AU2021105334A4

The present invention generally relates to a system and method for dual model-based early prediction of heart disease for Indian type-2 diabetes mellitus patients. The first model is a full model which tested all of the collected variables, whereas the second model is a partial model and it consisted of selected variables. The patients are included in the system sample if they experienced angiography, left ventricular hypertrophy, left anterior hemiblock, myocardial infarction, right bundle branch block, left bundle branch block, left ventricular diastolic dysfunction, angina, coronary artery bypass grafting and ischemic cardiomyopathy within the follow up time period of 5 years. N co CN CD Ea- --Ii >L

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Membrane layers for analyte sensors

NºPublicación: AU2021257924A1 18/11/2021

Solicitante:

DEXCOM INC [US]

US_2021356420_A1

Resumen de: AU2021257924A1

Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than -50C.

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ISLET-LIKE CELL CLUSTER, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

NºPublicación: WO2021228104A1 18/11/2021

Solicitante:

CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE CHINESE ACAD OF SCIENCES [CN]

CN_113637630_A

Resumen de: WO2021228104A1

Provided is an artificially cultured islet-like cell cluster, characterized in that: the cell cluster is obtained by stem cell differentiation. The cell cluster without enrichment comprises: (a) 20%-90% of islet β-cells; and (b) 5%-70% of islet α-cells. Human pluripotent stem cells are cultured to obtain a culture system of the islet-like cell cluster. Also provided are a model for constructing an islet microenvironment using the islet-like cell cluster, an artificial pancreas device prepared using the islet-like cell cluster, and a pharmaceutical composition containing the islet-like cell cluster. The artificially cultured islet-like cell cluster provided in the present invention can effectively release insulin under the stimulation of secretagogues such as glucose, and is used in an in vivo model of type I diabetes, so that the blood sugar level of a mouse having type I diabetes can remain within the normal range for a long time.

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BILATERALLY DRIVEN CLOSED-LOOP ARTIFICIAL PANCREAS

Nº publicación: WO2021227298A1 18/11/2021

Solicitante:

MEDTRUM TECH INC [CN]

WO_2021228232_A1

Resumen de: WO2021227298A1

A bilaterally driven closed-loop artificial pancreas, comprising: a detection module (100); an infusion module (102), including: a drug storage unit (1150); a screw (1170) and a driving wheel (1130) provided with wheel teeth, the driving wheel (1130) drives the screw (1170) and the screw (1170) pushes a piston (1160); a driving unit (1100) cooperating with the driving wheel (1130), the driving unit (1100) includes at least two driving portions (1110); a power unit (1180) connected to the driving unit (1100), the power unit (1180) outputs two forces in two directions on the driving unit (1100); and a program module (101). And the power unit (1180) is controlled by the program module. The artificial pancreas has higher infusion efficiency and can enhance user experience.

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