TECNOLOGÍA PARA LA MONITORIZACIÓN Y CONTROL DE LA DIABETES

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Resultados 92 resultados LastUpdate Última actualización 21/10/2019 [17:02:00] pdf PDF xls XLS




Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days



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SENSOR ASSEMBLY APPARATUS AND METHODS FOR CONTINUOUS GLUCOSE MONITORS

NºPublicación: WO2019197519A1 17/10/2019

Solicitante:
ASCENSIA DIABETES CARE HOLDINGS AG [CH]

Resumen de: WO2019197519A1

A sensor apparatus for a continuous glucose monitoring system has a sensor housing that includes a first end having a sealing surface configured to seal against an introducer having an insertion shaft, a second end having a sealing surface configured to seal against an insertion shaft cover, and an insertion shaft opening having a width that allows the insertion shaft to travel there through and that extends between the first and second ends. The sensor housing may further include a sensor wire channel that extends between the insertion shaft opening and a sensor wire contact location in an outer surface of the sensor housing. The sensor wire channel and sensor wire contact location may be configured to receive a sensor that extends between the insertion shaft opening and the sensor wire contact location to allow the sensor to make electrical contact to system circuitry. Numerous other aspects are provided.



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SENSOR ASSEMBLY APPARATUS AND METHODS FOR CONTINUOUS GLUCOSE MONITORS

NºPublicación: US2019313950A1 17/10/2019

Solicitante:
ASCENSIA DIABETES CARE HOLDINGS AG [CH]

Resumen de: US2019313950A1

A sensor apparatus for a continuous glucose monitoring system has a sensor housing that includes a first end having a sealing surface configured to seal against an introducer having an insertion shaft, a second end having a sealing surface configured to seal against an insertion shaft cover, and an insertion shaft opening having a width that allows the insertion shaft to travel there through and that extends between the first and second ends. The sensor housing may further include a sensor wire channel that extends between the insertion shaft opening and a sensor wire contact location in an outer surface of the sensor housing. The sensor wire channel and sensor wire contact location may be configured to receive a sensor that extends between the insertion shaft opening and the sensor wire contact location to allow the sensor to make electrical contact to system circuitry. Numerous other aspects are provided.



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ORGANISM ANALYZING APPARATUS AND ORGANISM ANALYZING METHOD

NºPublicación: US2019313951A1 17/10/2019

Solicitante:
SEIKO EPSON CORP [JP]

Resumen de: US2019313951A1

An organism analyzing apparatus includes an information acquiring section configured to acquire an amount of change in a blood glucose level due to ingestion of an organism and a sugar-content estimating section configured to estimate, according to the amount of change in the blood glucose level, sugar content ingested by the organism through the ingestion.



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METHODS AND APPARATUS FOR MONITORING AND ENCOURAGING HEALTH AND FITNESS

NºPublicación: US2019313965A1 17/10/2019

Solicitante:
DUGAN BRIAN M [US]

Resumen de: US2019313965A1

Methods and apparatus are provided for monitoring and encouraging health and fitness. In accordance with a first aspect, an apparatus is provided that is adapted to assist in weight loss and exercise. The apparatus comprises a personal digital assistant (PDA) having computer program code adapted to assist in at least one of calorie counting, meal selection, meal suggestion, weight monitoring, weight loss or gain monitoring, fat consumption monitoring, sugar consumption monitoring and salt consumption monitoring. The PDA also includes computer program code adapted to display historical data regarding at least one of calorie counting, meal selection, meal suggestion, weight monitoring, weight loss or gain monitoring, fat consumption monitoring, sugar consumption monitoring and salt consumption monitoring. Numerous other embodiments are provided, as are methods, systems and computer program products.



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SYSTEM AND METHOD FOR DYNAMICALLY CALIBRATING AND MEASURING ANALYTE CONCENTRATION IN DIABETES MANAGEMENT MONITORS

NºPublicación: US2019317104A1 17/10/2019

Solicitante:
BECTON DICKINSON CO [US]

Resumen de: US2019317104A1

An optical analyte sensor and diabetes management system is provided. The sensor preferably includes a hydrogel matrix for receiving a sample containing an analyte at unknown concentration, a light emitter for emitting light at a stimulation frequency, a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, for measuring an intensity of the fluorescence signal and the first and second frequencies. A processor determines a concentration of the analyte based on the respective intensities.



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SYSTEM AND METHOD FOR INDUCTIVELY CHARGING A MEDICAL DEVICE

NºPublicación: WO2019199952A1 17/10/2019

Solicitante:
TANDEM DIABETES CARE INC [US]

Resumen de: WO2019199952A1

Methods and systems are disclosed wherein temperature in a device such as an ambulatory infusion pump is monitored during inductive charging of the device such that temperature-sensitive contents or components, such as, for example, insulin, particular circuitry and/or other components are not damaged. Temperature can be monitored in the device at one or more locations during inductive charging. If the temperature breaches one or more predetermined thresholds and/or is rising at a rate greater than one or more predetermined thresholds, charging can be suspended or provided at reduced power to prevent the temperature from further rising and damaging the contents and/or components of the device. One or more alerts associated with these events may also be triggered so that the user is aware of the situation and may take corrective action.



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TRACKING CHANGES IN AVERAGE GLYCEMIA IN DIABETICS

NºPublicación: US2019318801A1 17/10/2019

Solicitante:
UNIV VIRGINIA PATENT FOUNDATION [US]

Resumen de: US2019318801A1

A method, system and computer readable medium for tracking changes in average glycemia in diabetes is based on a conceptually new approach to the retrieval of SMBG data. Using the understanding of HbA1c fluctuation as the measurable effect of the action of an underlying dynamical system, SMBG provides occasional glimpses at the state of this system and, using these measurements, the hidden underlying system trajectory can be reconstructed for individual diabetes patients. Using compartmental modeling a new two-step algorithm is provided that includes: (i) real-time estimate of HbA1c from fasting glucose readings, updated with any new incoming fasting SMBG data point(s), and (ii) initialization and calibration of the estimated HbA1c trace with daily SMBG profiles obtained periodically. The estimation of these profiles includes a factorial model capturing daily BG variability within two latent factors.



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CLOSED LOOP CONTROL ALGORITHM FOR AN ARTIFICIAL PANCREAS

NºPublicación: US2019314572A1 17/10/2019

Solicitante:
MEDTRUM TECH INC [CN]

Resumen de: US2019314572A1

The present invention provides a closed loop control method to control an artificial pancreas and the artificial pancreas using this method, comprising constructing an autoregressive model by initiatively introducing the insulin absorption lag factor, calculating an amount of insulin to be delivered at the current time using the autoregressive model and a PID controller respectively, and tuning the parameters of the autoregressive model and the PID controller respectively using the average of the calculation results in order to provide a more accurate prediction of glucose trends and a more desirable amount of insulin delivery.



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DISTRIBUTED SYSTEM ARCHITECTURE FOR CONTINUOUS GLUCOSE MONITORING

NºPublicación: US2019313905A1 17/10/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019313905A1

The present disclosure relates to techniques for receiving glucose data from a continuous glucose sensor and controlling the use and redistribution of that data so it is used in an intended manner. In one aspect, a system includes a plurality of continuous glucose monitor (CGM) devices; a plurality of display devices to receive data from the CGM devices classified into a plurality of classifications based on data type; a cloud server architecture to receive the data from the display devices on an intermittent basis, in which the data routed to a particular server of the plurality of servers is determined by the data type, and in which the intermittent basis varies depending upon data type; a plurality of remote monitor display devices; and an analysis and report engine.



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Closed loop control of physiological glucose

NºPublicación: AU2018261124A1 17/10/2019

Solicitante:
LILLY CO ELI

Resumen de: AU2018261124A1

The present disclosure relates to systems and methods for controlling physiological glucose concentrations in a patient using a closed loop artificial pancreas. The systems and methods may utilize a controller with control logic operative to execute a multi-model predictive controller algorithm to determine a medication dose to the patient.



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HEALTH DEVICE FOR SMART HOME CARE

NºPublicación: EP3552537A1 16/10/2019

Solicitante:
CHEN KAIPO [TW]

Resumen de: EP3552537A1

A smart home-care health device 1 includes a health device 1 including a master control board 11 for household application. The master control board 11 is electrically connected with multiple modules arranged in the health device 1. The detection modules 14 connected to the master control board 11 include a blood glucose detection module, a sleep detection module 146, and a heart detection module 147, which allow for acquisition of detailed and correct data of a target body 2 through non-contact detections and allows, through feed-back, transmission to the master control board 11 for judgment in order to establish personal dedicated message corresponding to the status of the target body 2 and allow for message transmission to a clinic or a hospital and electrical appliances 3 to allow family members to receive perfect home care of smart home.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: US2019307381A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307381A1

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.



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SYSTEM AND METHOD FOR A CLOSED LOOP CONTROL IN AN ARTIFICIAL PANCREAS

NºPublicación: US2019307958A1 10/10/2019

Solicitante:
MEDTRUM TECH INC [CN]

Resumen de: US2019307958A1

The present invention provides a closed loop control method in an artificial pancreas and a system using the method, comprising sensing an activity level of a patient by at least one motion sensor and providing signals to at least one processer; then adjusting a series of related algorithms depending partly on the signals by the processer to provide more accurate and reliable data that is the basis of desirable treatment plans, and sending corresponding instructions by the processer for automatic operations of the artificial pancreas to realize a closed loop control.



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SYSTEM AND METHOD FOR INDUCTIVELY CHARGING A MEDICAL DEVICE

NºPublicación: US2019307952A1 10/10/2019

Solicitante:
TANDEM DIABETES CARE INC [US]

Resumen de: US2019307952A1

Methods and systems are disclosed wherein temperature in a device such as an ambulatory infusion pump is monitored during inductive charging of the device such that temperature-sensitive contents or components, such as, for example, insulin, particular circuitry and/or other components are not damaged. Temperature can be monitored in the device at one or more locations during inductive charging. If the temperature breaches one or more predetermined thresholds and/or is rising at a rate greater than one or more predetermined thresholds, charging can be suspended or provided at reduced power to prevent the temperature from further rising and damaging the contents and/or components of the device. One or more alerts associated with these events may also be triggered so that the user is aware of the situation and may take corrective action.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: WO2019195661A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: WO2019195661A1

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.



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CONTINUOUS GLUCOSE MONITORING DEVICE

NºPublicación: US2019307380A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307380A1

The sensor includes a working electrode having a first wire with a first flat surface and an electrochemical element on the first flat surface. A reference electrode includes a second wire with a second flat surface and a counter electrode includes a third wire with a third flat surface. The first wire is a first sensor wire for the working electrode, the second wire is a second sensor wire for the reference electrode and the third wire is a third sensor wire for the counter electrode in a plurality of sensor wires. The second flat surface and the third flat surface face toward each other.



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ENHANCED GLUCOSE LIMITING MEMBRANE FOR A WORKING ELECTRODE OF A CONTINUOUS BIOLOGICAL SENSOR

NºPublicación: US2019307379A1 10/10/2019

Solicitante:
ZENSE LIFE INC [US]

Resumen de: US2019307379A1

Briefly, a sensor for a continuous biological monitor is provided that has a working electrode with a new interfere layer that is (1) non-electron conducting, (2) ion passing, and (3) permselective for molecular weight. The new interference layer is made by mixing a monomer and a mildly basic buffer, and then electropolymerizing the monomer and the buffer into a polymer. The polymer is deposited onto a working electrode for a continuous metabolic monitor, for example, using an electro depositing process in the form of cyclic voltammety (CV). The interference layer is permselectable for molecule size by adjusting the pH of the basic buffer.



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FLUID DELIVERY DEVICE WITH TRANSCUTANEOUS ACCESS TOOL, INSERTION MECHANISM AND BLOOD GLUCOSE MONITORING FOR USE THEREWITH

NºPublicación: EP3549524A1 09/10/2019

Solicitante:
INSULET CORP [US]

Resumen de: EP3549524A1

A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool including a needle or a trocar; and a transcutaneous access tool insertion mechanism for deploying the transcutaneous access tool, wherein the insertion mechanism is configured to insert and retract the needle/trocar in a single, uninterrupted motion. In certain embodiments, the fluid delivery device may comprise an infusion device comprising a fluid reservoir for containing a therapeutic fluid; and a transcutaneous access tool fluidly coupled to the fluid reservoir for delivering the therapeutic fluid subcutaneously and for introducing a monitoring test strip subcutaneously, and methods of use thereof.



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Capturing and Analyzing Hypoglycemic Event Data to Identify Treatment Options

NºPublicación: US2019298236A1 03/10/2019

Solicitante:
GLOOKO INC [US]

Resumen de: US2019298236A1

Systems, methods, and computer readable storage media manage low blood glucose levels. The system receives blood glucose readings, where each reading includes a blood glucose value and a respective timestamp. The system compares each blood glucose reading to a predefined hypoglycemic event threshold, and identifies hypoglycemic events when a respective blood glucose reading is below the predefined hypoglycemic event threshold. For at least a subset of the identified hypoglycemic events, the system prompts a user for information associated with each hypoglycemic event. The information requested includes one or more of: symptoms associated with the respective hypoglycemic event; perceived causes of the respective hypoglycemic event; and treatment for the respective hypoglycemic event. In response to the prompting, the system obtains feedback about the identified hypoglycemic events and provides a report that includes at least a subset of the obtained feedback.



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GLUCOSE SENSORS AND METHODS OF MANUFACTURE THEREOF

NºPublicación: US2019300925A1 03/10/2019

Solicitante:
UNIV CONNECTICUT [US]

Resumen de: US2019300925A1

Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the working electrode; the first layer of the first hydrogel being operative to store oxygen; wherein the amount of stored oxygen is proportional to the number of freeze-thaw cycles that the hydrogel is subjected to; and a second layer of the second hydrogel. Disclosed too is a method that comprises using periodically biased amperometry towards interrogation of implantable glucose sensors to improve both sensor's sensitivity and linearity while at the same time enable internal calibration against sensor drifts that originate from changes in either electrode activity or membrane permeability as a result of fouling, calcification and/or fibrosis.



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FLEXIBLE PATCH FOR FLUID DELIVERY AND MONITORING BODY ANALYTES

NºPublicación: US2019298921A1 03/10/2019

Solicitante:
ABBOTT DIABETES CARE INC [US]

Resumen de: US2019298921A1

A wearable, conductive textile patch is provided that may include any of a number of features for monitoring body analytes and/or delivering fluids to a body. In one embodiment of the invention, a single, patch-mounted system monitors glucose levels of a diabetic person and provides appropriate doses of insulin in response to the glucose measurements. A hand-held user interface can be provided for wirelessly controlling the system and/or receiving information from it. Conductive pathways can be formed in the fabric of the patch. Components that can be integrated into the flexible patch include a power source, controller, transmitter, antenna, temperature and other sensors, fluid pump, infusion set, electrical pathways, switches, controls, electrodes, connectors, resistors and other circuit elements. Such components can be embedded, interwoven or coated on to the flexible patch instead of or in addition to surface mounting. Methods associated with use of the flexible patch system are also covered.



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INTEGRATION OF INFUSION PUMP WITH REMOTE ELECTRONIC DEVICE

NºPublicación: US2019298915A1 03/10/2019

Solicitante:
TANDEM DIABETES CARE INC [US]

Resumen de: US2019298915A1

A system and method can provide for a remote electronic device to be used to remotely initiate delivery of a medicament bolus with a medical device, such as an insulin pump, with the medical device providing audible or tactile confirmation of the programmed bolus. The bolus amount can be calculated by or programmed or otherwise entered into the smartphone, etc., and then transmitted to the medical device. When the pump receives the transmitted bolus amount, it issues one or more indications such as audible sounds and/or vibrations in any number of desired combinations. For instance, each individual sound or vibration may correspond to an increment of the medicament. The user can therefore determine the size of the medicament bolus by the number of sounds or vibrations and can confirm or cancel delivery of the bolus.



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CELL THERAPY FOR PATIENTS

NºPublicación: US2019298766A1 03/10/2019

Solicitante:
YANG DEMAO [US]

Resumen de: US2019298766A1

Materials and methods of treating a patient with type 2 diabetes mellitus, metabolic syndrome, obesity, infertility, high blood pressure, hyperthyroidism, and hypothyroidism, hyperlipidaemia, osteoporosis, osteoarthritis, hypoadrenalism, polycystic ovary syndrome, or Parkinson's disease comprising administering a therapeutically effective amount of ex vivo cultured activated peripheral blood mononuclear cells (PBMCs) to the patient. The ex vivo cultured activated cells are activated and cultured in a presence of a cytokine and may be autologous or allogeneic relative to the patient.



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SYSTEMS AND METHODS FOR MANAGING GLYCEMIC VARIABILITY

NºPublicación: US2019298922A1 03/10/2019

Solicitante:
DEXCOM INC [US]

Resumen de: US2019298922A1

Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.



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METHOD AND DEVICES FOR PRESSURE DETERMINATION IN AN INSULIN PUMP

Nº publicación: US2019298916A1 03/10/2019

Solicitante:
ROCHE DIABETES CARE INC [US]

Resumen de: US2019298916A1

A method for connecting a force sensor to a circuit board is disclosed. A circuit board having first and second conductive leads located on the same surface of the circuit board is provided. Also provided is a force sensor with a first flexible contact tab having a first contact pad and a second flexible contact tab having a second contact pad. The first contact pad is arranged to face the first conductive lead. A first conductive rubber element establishes an electrical connection between the first contact pad and the first conductive lead, and the second contact pad and the second conductive lead are arranged to face in the same direction. A second conductive rubber element establishes an electrical connection between the second contact pad and the second conductive lead. Also disclosed are an associated device for determining fluid pressure in an insulin pump and an insulin pump.


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