BIOIMPRESIÓN 3D

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Resultados 105 resultados LastUpdate Última actualización 15/10/2019 [16:41:00] pdf PDF

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days

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引导放射粒子近距离治疗癌症的腔内定位导板及制作方法

NºPublicación: CN110314288A 11/10/2019

Solicitante:

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Resumen de: CN110314288A

本发明提供了引导放射粒子近距离治疗癌症的定位导板,包括:定位板、植入腔、定位线/定位孔和植入针孔,所述定位板位于植入腔的下部,所述定位线/定位孔位于定位板上,所述植入针孔位于植入腔内部并由植入腔的底部穿出。该导板设计好后通过3D打印制造,生产方便快捷,导板为每位患者一对一定制和一次性使用或多次使用,消除了劳动密集的清洗、浸泡、重复消毒的需要,减少了生物及化学污物残留以及不同患者反复使用交叉感染的风险。该导板实现了术前计划和术中实施的吻合,根据处方剂量设计好进针方向角度,使粒子植入计量学质量控制得到保障。

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一种唇腭裂牙槽塑形腭护板的数字化制作方法

NºPublicación: CN110313999A 11/10/2019

Solicitante:

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Resumen de: CN110313999A

本发明提供一种唇腭裂牙槽塑形腭护板的数字化制作方法,利用3D扫描仪直接扫描患者口腔或扫描口腔模型,获取患者口腔内牙槽骨形态的数字化模型;标定颌骨标志点;根据治疗前后颌骨移动的规律,标记颌骨标志点的术前坐标、术后坐标和坐标差值,将每个标志点的坐标差值分解,得到每一步的牙槽骨状态,虚拟添加腭护板,腭护板包括基托和设置在基托侧向的连接杆;导出每一步的腭护板和对应的调整模型;将腭护板与对应的调整模型进行装配,合并为一个整体模型;通过调整腭护板的厚度数据,将腭护板实体化,输入3D打印机进行打印,得到每一步的腭护板实物。本发明能够避免装置间的相互作用力,且个性化设计唇腭裂牙槽塑形腭护板。

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牙体预备手术导板及其制备方法、系统、使用方法

NºPublicación: CN110313997A 11/10/2019

Solicitante:

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Resumen de: CN110313997A

本发明公开了牙体预备手术导板及其制备方法、系统、使用方法,本发明通过设计虚拟目标修复体、虚拟理想预备体、虚拟导板引导方式、牙体预备导板及3D打印成型,综合考虑了现有牙齿外形、未来修复体外形、理想预备体外形,可微创精准的完成牙体预备,并全程数字化进行控制和操作,制作的流程简单,提高了制作效率、减小了制作误差,大大减少了医生临床操作的时间。

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数字化种植引导粘接导板的制作方法及引导粘接导板

NºPublicación: CN110314003A 11/10/2019

Solicitante:

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Resumen de: CN110314003A

本发明公开了数字化种植引导粘接导板的制作方法,包括以下步骤:种植手术方案设计;植体三维空间的获取;修复体的设计;引导就位及粘接导板的设计;修复体组织面均一化处理;导板与修复体打孔处理;导板与修复体成型。本发明通过改变数字化技术,在术前以手术设计的牙种植体三维空间相对位置为指导,设计并制作临时修复体,同时设计并3D打印数字化即刻修复引导就位及粘接导板,种植手术完成后,在导板的引导下完成就位,复原虚拟设计中的空间位置,并以此位置进行修复体与临时基台的粘接,最终完成即刻修复。

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数字化钛合金种植手术导板及其制备方法

NºPublicación: CN110314002A 11/10/2019

Solicitante:

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Resumen de: CN110314002A

本发明公开了数字化钛合金种植手术导板及其制备方法,本发明包括虚拟排牙、种植方案设计、种植导板设计、3D打印支撑设计、3D打印成型以及后处理,通过改进数字化的导板设计方法,并配合金属3D打印技术和钛合金的性能要求,提供一种数字化钛合金种植手术导板及其制备方法,制作出新型的种植手术导板(数字化钛合金种植手术导板),以提供全新的临床手术引导方式。

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ORAL CARE DEVICE AND ORAL CARE METHOD

NºPublicación: CN110325145A 11/10/2019

Solicitante:

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JP_2019005538_A

Resumen de: US2018368957A1

An oral care device for providing oral-cavity information to a user or a manager includes: a liquid supply unit; a mouthpiece connected to the liquid supply unit and including a spatial portion configured to accommodate at least one of an upper tooth side and a lower tooth side when the mouthpiece is inserted into an oral cavity; a pump connected to the mouthpiece and configured to suction liquid from the liquid supply unit and introduce the liquid into the spatial portion and to suction fluid from the spatial portion; a storage unit connected to the pump and configured to store or discharge fluid suctioned from the spatial portion; and a measuring unit connected to the storage unit and configured to measure a state of fluid stored in the storage unit, wherein liquid is introduced to the spatial portion from the liquid supply unit only by suction force of the pump.

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数字化备牙及种植联合手术导板的制作方法及手术导板

NºPublicación: CN110314004A 11/10/2019

Solicitante:

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Resumen de: CN110314004A

本发明公开了数字化备牙及种植联合手术导板的制作方法,包括:获取包含口腔情况的术前模型,并获取数据;确定目标修复体,并获得蜡型数据;将目标修复体进行等厚度缩小后,进行精修和光滑处理形成虚拟牙体;确定种植体在术前模型、数据和蜡型数据中的三维位置;修正手术引导环模型;延伸得到手术导板模型;通过3D打印对联合手术导板模型打印成型。本发明还公开了一种手术导板。本发明利用数字化设计技术并通过3D打印技术设计出了手术导板,并且在建模过程中同时完成了牙体预备手术设计、种植手术设计、种植基台取模和预备基牙取模,减少了临床操作步骤和就诊次数,节约了相应的材料成本和时间成本。

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一种耳朵抗瘢矫形器

NºPublicación: CN209474958U 11/10/2019

Solicitante:

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Resumen de: CN209474958U

一种耳朵抗瘢矫形器,设置有耳前罩、耳后罩,使用时将耳前罩与耳后罩分别固定在耳朵的两侧,通过耳前罩与耳后罩对耳朵进行包裹,并通过耳前轮保护延伸片与耳后轮保护延伸片形成对耳朵的更加完全的包裹,并且在耳前轮保护延伸片上的前固定片与耳后轮保护延伸片上的后固定片在固定时,能够直接对使用者的耳朵进行完整包覆,且保证本耳朵抗瘢矫形器的边缘对使用者的耳朵不会造成二次擦伤。通过设置前固定片与后固定片同时还能够保持当耳前罩与耳后罩对使用者的耳朵形成包裹时进一步用连接固定件进行固定时能够施加一定的压力,促进烧伤耳朵的愈合,解决了直接加压局部导致的不适,通过直接3D打印,使每个矫形器都完全贴合、美观。

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一种基于单片机的3D打印支具

NºPublicación: CN209474895U 11/10/2019

Solicitante:

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Resumen de: CN209474895U

一种基于单片机的3D打印支具,设置有支具主体和用于感应用户对支具主体施加压力的大小及向外部设备输出信息的控制机构,控制机构嵌装于支具主体。该3D打印支具能够实时采集用户的足部与支具主体间的压力情况,并将足部与支具主体间的压力情况信息发送至外部设备,实现康复训练时用户患肢多点受力情况的实时监测,便于医护人员观察用户的康复进程。该3D打印支具制作简便和成本低,在功能上能提供实时服务,且快捷灵活和容易操作。一种支具主体制备方法包括有5个步骤。该支具主体制备方法针对用户进行个性化制造,在用户使用该支具主体时能有效辅助促进血液循环和防止肌肉萎缩,同时该支具主体能够促进关节活动度并可进行用户下肢的协调。

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SURGICAL CLAMP PRODUCED BY ADDITIVE MANUFACTURING AND METHOD FOR PRODUCING SUCH A CLAMP

NºPublicación: CN110325128A 11/10/2019

Solicitante:

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DE_102017105706_A1

Resumen de: WO2018166989A1

The invention relates to a surgical clamp (1) comprising at least a first instrument shank (3) and a second instrument shank (2), which can be moved in relation to each other, the first instrument shank (3) being embodied as a male instrument shank (3) with a male bearing section (9), and the second instrument shank (2) being embodied as a female instrument shank (2) with a female bearing section comprising a through-opening (10), the first instrument shank (3) being arranged on the second instrument shank (2) by the male bearing section (9) engaging through the through-opening (10) of the female bearing section (6), the instrument (1) being produced by means of an additive manufacturing method. The invention further relates to a method for producing such an instrument.

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一种个性化骨科外固定全自动3D打印的方法

NºPublicación: CN110314028A 11/10/2019

Solicitante:

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Resumen de: CN110314028A

本发明提供了一种个性化骨科外固定全自动3D打印的方法,包括通过PC端主控台,将患者信息录入;在PC端主控台启动扫描,模型生成、打印方位调整、表面打孔、自动生成3D打印控制指令、输出每层的打印坐标信息、每层相邻线段夹角计算及输出、外固定打印,该方法自动化程度高,操作简单,简化设计流程,适用于临床医生用于异形打印头的骨科个性化外固定的3D实物打印。

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DRUG DELIVERY SYSTEM COMPRISING A NON-STEROIDAL ANTI-INFLAMMATORY (NSAID) AND A PROGESTOGENIC COMPOUND AND METHODS FOR MANUFACTURING

NºPublicación: LT3247327T 10/10/2019

Solicitante:

BAYER OY [FI]

JP_2018502878_A

Resumen de: WO2016116502A1

The invention is describing an intrauterine delivery system comprising non-steroidal anti-inflammatory (NSAID) and a progestogenic compound, containing anti-inflammatory active compound in the frame material and that the progestogenic compound is contained in a silicon based reservoir attached to the frame, wherein the frame consist of a thermoplastic material. A further object of the invention is to fabricate drug-containing T-intrauterine systems (I US) with the drug incorporated within the entire backbone of the medical device by using 3D printing technique, based on fused deposition modelling (FDM™). Indomethacin was used to prepare drug-loaded poly-caprolactone (PCL)-based filaments with different drug contents 5—40 wt%, namely 5%, 15% and 30% wt%:of Indomethacin.

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BIODEGRADABLE ELASTIC HYDROGELS FOR BIOPRINTING

NºPublicación: WO2019195256A1 10/10/2019

Solicitante:

UNIV TEXAS [US]
UNIV NORTHEASTERN [US]

Resumen de: WO2019195256A1

Disclosed herein are hydrogel compositions comprising a triblock copolymer having a formula A-B-A, wherein A is a polycaprolactone (PCL) block or a polyvalerolactone (PVL) block and B is a polyethylene glycol (PEG) block. Also disclosed are methods of making a hydrogel comprising providing a photoinitiator and a triblock copolymer having a formula A-B-A, wherein the triblock copolymer comprises one or more ethylenically unsaturated moieties; and photocrosslinking the triblock copolymer, thereby forming a hydrogel. Also disclosed are methods of printing a three-dimensional (3D) article comprising extruding a printing composition from a deposition nozzle moving relative to a substrate, the printing composition comprising a photoinitiator and any herein disclosed triblock copolymer, wherein the triblock copolymer comprises one or more ethylenically unsaturated moieties; depositing one or more layers comprising the printing composition on the substrate; and photocrosslinking the triblock copolymer to form the printed 3D article.

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INTERFACE DEVICE FORMABLE BY ADDITIVE MANUFACTURING PROCESS

NºPublicación: US2019307980A1 10/10/2019

Solicitante:

KONINKLIJKE PHILIPS NV [NL]

CN_109803705_A

Resumen de: US2019307980A1

An interface device is structured to be connected in fluid communication with a source of breathing gas and to provide a flow of breathing gas to the airways of a patient. The interface device includes a support (24), a deformable portion (28) situated on the support, and an interface portion (32) situated on the deformable portion and being structured to be engaged with the patient in the vicinity of the airways, with the deformable portion including a plurality of deformable elements (36) that form a lattice structure and that are connected with the support at a plurality of spaced apart points of connection (44) on the support. The interface device may be formed via an additive manufacturing process.

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Dental Prosthetic Moulds and Moulding Methods

NºPublicación: US2019307537A1 10/10/2019

Solicitante:

FUNG JOHN [AU]

CN_110087582_A

Resumen de: US2019307537A1

A method of forming a plurality of compression moulds for moulding prosthetic tooth elements is disclosed. A natural tooth surface or a model of the natural tooth surface is scanned to obtain scan data. Based on the scan data, a first compression mould is formed comprising a first mould surface, the first mould surface having a shape corresponding to a shape of a natural tooth surface increased in size by a first scale factor. Based on the scan data, a second compression mould is formed comprising a second mould surface, the second mould surface having a shape corresponding to the shape of the natural tooth surface increased in size by a second scale factor, the second scale factor being different from the first scale factor. Prosthetic tooth elements and dental prostheses formed using the method are also disclosed.

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Polymeric Materials and Articles Manufactured There From

NºPublicación: US2019309238A1 10/10/2019

Solicitante:

PROCTER & GAMBLE [US]
VIRGINIA TECH INTELLECTUAL PROPERTIES INC [US]

Resumen de: US2019309238A1

A water-soluble polyurethane derived from: polyethylene glycol, polyethylene glycol-block-polypropylene glycol-block-polyethylene glycol polymer, polypropylene glycol-block-polyethylene glycol-block-polypropylene and mixtures thereof, 1,1′-Carbonyldiimidazole, polyamine and mixtures thereof.

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Three Dimensional Bioprinted Tumor Models for Drug Testing

NºPublicación: US2019309264A1 10/10/2019

Solicitante:

ORGANOVO INC [US]
UNIV OREGON HEALTH & SCIENCE [US]

WO_2018035138_A1

Resumen de: US2019309264A1

Described are three-dimensional, engineered, biological cancer models, methods of producing the same, and methods of identifying a therapeutic agent for cancer in an individual utilizing the three-dimensional, engineered, biological cancer models.

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Preparation and Applications of 3D Bioprinting Bioinks for Repair of Bone Defects, Based on Cellulose Nanofibrils Hydrogels with Natural or Synthetic Calcium Phosphate Particles

NºPublicación: US2019307923A1 10/10/2019

Solicitante:

CELLINK AB [SE]

Resumen de: US2019307923A1

The present invention relates to preparation of bioink composed of cellulose nanofibril hydrogel with native or synthetic Calcium containing particles. The concentration of the calcium containing particles can be between 1% and 40% w/v. Such bioink can be 3D Bioprinted with or without human or animal cells. Coaxial needle can be used where cellulose nanofibril hydrogel filled with Calcium particles can be used as shell and another hydrogel based bioink mixed with cells can be used as core or opposite. Such 3D Bioprinted constructs exhibit high porosity due to shear thinning properties of cellulose nanofibrils which provides excellent printing fidelity. They also have excellent mechanical properties and are easily handled as large constructs for patient-specific bone cavities which need to be repaired. The porosity promotes vascularization which is crucial for oxygen and nutrient supply. The porosity also makes it possible for further recruitment of cells which accelerate bone healing process. Calcium containing particles can be isolated from autologous bone, allogenic bone or xenogeneic bone but can be also isolated from minerals or be prepared by synthesis. Preferable Calcium containing particles consist of β-tricalcium phosphate which is resorbable or natural bone powder, preferably of human or porcine origin. The particles described in the present invention have particle size smaller than 400 microns, or more preferably smaller than 200 microns, to make it possible to han

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Spoedmedicatiehouder voor zorgverleners

NºPublicación: NL1042806B1 10/10/2019

Solicitante:

DOC BLOX [NL]

Resumen de: NL1042806B1

Het ontwerpt betreft een container welke bestemd is voor hulpverleners, welke zich kenmerkt door een gestructureerde en logische indeling van spoedmedicatie of andere hulpmiddelen, waardoor de hulpverlener bij gebruik een snel overzicht heeft en bij het beheren van spoedmedicatie weinig tot geen tijd kwijt is, doordat de hulpverlener een kant-en-klaar, doordacht en compact product koopt. De indeling is logisch en overzichtelijk doordat het zo goed mogelijk medicatie verdeelt volgens richtlijnen in de spoedzorg (Het zogenaamde ABCD protocol). Doordat de container verstrekt wordt inclusief medicatie is de zorgverlener geen tijd kwijt aan controle en verdeling van ampullen. Naast de logische en gestructureerde verdeling biedt de container ook ruimtebesparing in meestal beperkte ruimte in bijvoorbeeld dokterstassen. Het modulaire ontwerp zorgt ervoor dat andere containers voor andere hulpmiddelen makkelijk op elkaar aansluiten.

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APPARATUS AND METHOD FOR THE AUTOMATED PRODUCTION OF CUSTOMIZABLE DOSAGE FORMS

NºPublicación: WO2019193060A1 10/10/2019

Solicitante:

DE GIORGI CARLO [IT]

Resumen de: WO2019193060A1

An apparatus (10, 100, 1000) for the automated production of customizable dosage forms, comprising a sterile chamber (20) inside which a dosage form is formed, comprising: - a core supporting assembly (30) for retaining a core (9) inside the sterile chamber (20), - one or more dispensing devices (50), each of which is configured to emit, in a controlled manner, in the direction of the core (9), a jet (g) of a pharmaceutical compound, - a motor assembly (40), adapted to transmit a rotation about a central rotation axis (Y) to the core supporting assembly (30) and with it to the core (9) or to at least one dispensing device (50); the motor assembly (40) and the dispensing devices (50) being configured so that during rotation the dispensing devices (50) deposit one or more layers (1', 1'') of a predefined thickness of pharmaceutical compounds on a perimetric portion of the core (9).

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THREE-DIMENSIONAL PRINTING OF COLLOIDAL BUILDING BLOCKS FOR WOUND HEALING MATERIALS

NºPublicación: WO2019195681A1 10/10/2019

Solicitante:

UNIV NORTH CAROLINA STATE [US]

Resumen de: WO2019195681A1

Bio-ink compositions comprising bio-compatible microgels or nanogels are described. The bio-inks can comprise, for example, micro- or nanogels comprising crosslinked poly(N-isopropylacrylamide) (poly-NIPam). The bio- inks can further comprise viscosity control agents, such as poly(ethylene glycol) (PEG), and/or surface tension agents. Three-dimensional (3D) printing (e.g., piezoelectric printing) of the bio-inks can provide 3D printed materials comprising microgel or nanogel assemblies of the bio-ink compositions. These materials can be used as scaffolds for preparing biological tissues for use, for instance, in regenerative medicine.

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PRINTING DEVICE AND COMPOSITION COMPRISING MAGNETIC COLOR CHANGEABLE MICROCAPSULES

NºPublicación: WO2019193169A1 10/10/2019

Solicitante:

SOC BIC [FR]

KR_20190022291_A

Resumen de: WO2019193169A1

This disclosure relates to a printing device for printing or dispensing a curable printing composition which is capable of changing color in response to the application of a magnetic field in the non-cured state. The printing device may be a handheld device such as a portable pen. The present disclosure further relates to curable compositions, cartridges and methods which may be used in combination with the aforementioned printing devices or in other applications.

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一种Ag-DBT/PVDF复合骨支架及其制备方法

NºPublicación: CN110302429A 08/10/2019

Solicitante:

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Resumen de: CN110302429A

本发明提供了一种Ag‑DBT/PVDF复合骨支架及其制备方法,所述复合骨支架由PVDF基体以及分散于PVDF基体中的Ag‑DBT组成,所述Ag‑DBT为表面负载有纳米银的聚多巴胺包覆BaTiO,所述制备方法采用多巴胺对BaTiO进行表面修饰得到DBT粉体;将DBT粉体分散至含Ag的溶液中,通过原位还原反应在BaTiO颗粒表面形成单质银,得到Ag‑DBT复合颗粒;将PVDF粉体与Ag‑DBT复合颗粒通过液相混合得到Ag‑DBT/PVDF复合粉体;所述复合粉体通过选择性激光烧结得到Ag‑DBT/PVDF复合骨支架;该方法利用BaTiO作为纳米银载体,不但可以强化加载在陶瓷颗粒上的极化电压,使外加电压足以实现BaTiO陶瓷颗粒中偶极子的完全偏转,增强复合材料支架压电性能,改善其生物性能,而且可以促进纳米银在PVDF基体中的分散,赋予复合材料支架良好的抗菌性能。

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基于活细胞3D打印的软骨-骨-骨髓复合组织结构及方法

NºPublicación: CN110302428A 08/10/2019

Solicitante:

\u4E2D\u56FD\u4EBA\u6C11\u89E3\u653E\u519B\u9646\u519B\u519B\u533B\u5927\u5B66\u7B2C\u4E00\u9644\u5C5E\u533B\u9662

Resumen de: CN110302428A

本发明公开了一种基于活细胞3D打印的软骨‑骨‑骨髓复合组织结构及方法,采集骨组织的生物信息,输入计算机进行仿生建模,配制适用软骨、成骨、间充质干、血管内皮等细胞的生物墨水;配制打印密致骨区域的硬材料硬材料;配制各种铸型剂;将活细胞按一定的密度接种于相应的生物墨水中;将各种类型的打印墨水分别加载于打印机料仓,设置打印参数后进行3D打印,打印成型的骨组织在组织工程仿生培养器中进行培养,一定时间后运用温控或酶控或光控的方法,于不同的时间祛除铸型剂材料,在软骨‑骨‑骨髓复合组织外部接枝人工血管,在组织工程仿生培养器内连续循环灌注培养,实现打印组织的预成熟。其实现3D打印骨组织的长期存活和生物功能。

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Printhead device for 3D bio-printer

Nº publicación: US10434713B1 08/10/2019

Solicitante:

UNIV TAIYUAN TECHNOLOGY [CN]

Resumen de: US10434713B1

A printhead device is provided. The printhead device includes a cell tube, a cell tube rubber plug covering the cell tube, a connector arranged at an end of the cell tube, and a fixing knob fixed to the connector and communicating with a printing nozzle through a bottom liquid tube. A fixing clip is provided on the upper part of the cell tube, and a stepping motor box is provided on the upper end of the fixing clip. An air valve box is arranged on the upper side of the stepping motor box, and a rotary air valve is provided in the air valve box. The rotary air valve communicates with the inner cavity of the cell tube through an internal vent tube, and with an air valve straight tube or an air valve gooseneck tube.

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