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210
resultados
Última actualización
05/09/2025 [06:47:00]
Resumen de: WO2025166097A1
Disclosed are systems and methods of a decision intelligence (DI)-based computerized framework that automatically and/or dynamically implements a color algorithm for performing staining and glazing dental restorations. The framework operates by leveraging determined color variations through AI/ML-based analysis that generate detailed color maps, which can be translated into precise printing instructions controlling the mixture and layering of dental-grade glazing materials. A printing system can employ multiple print heads with varying base colors and opacity levels to create microscopic color gradients and translucency effects matching natural tooth enamel. The disclosed automated processing applies personalized color patterns in microscopically thin layers, ensuring consistent glaze thickness while replicating regional variations across the tooth surface. Such approach eliminates manual glazing variability while achieving superior customization compared to traditional pre-set patterns, resulting in dental restorations that integrate seamlessly with existing teeth.
Resumen de: WO2025165052A1
The present invention relates to a method for activating natural killer cells, comprising a step of providing electrical stimulation to natural killer cells. Specifically, electrical stimulation under predetermined conditions is applied to natural killer cells by applying an electrical stimulation system established through a 3D-printed electrical stimulation device and a function generator. Here, cancer cell-killing ability and calcium ion-mediated mechanisms are analyzed among induced intracellular effects. In addition, with respect to the natural killer cells produced according to the present invention, a method capable of enhancing the efficacy of a cell therapeutic agent without introducing genetic modification is presented, and the cells can be used to study the correlation between the cancer cell-killing ability and the intracellular calcium ion levels of electrically stimulated natural killer cells.
Resumen de: WO2025164130A1
Provided are: a curable composition for three-dimensional stereolithography, which contains 100 parts by mass of a polymerizable monomer component (A), 40-400 parts by mass of an inorganic filler (B), 0.01-5 parts by mass of a photoinitiator (C), and 0.01-2.5 parts by mass of an activation light absorber (D), and in which 10-90 mass% of the inorganic filler (B) is contained as an organic-inorganic composite filler (E), the value of light scattering index Sc serving as an index of the proportion of light scattered laterally when being irradiated with activation light is 10% or less, and the rate of transmission for activation light in a state prior to being optically cured is 1-50%; and a method for producing the curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic product and a method for producing a dental restoration article, in both of which said curable composition for three-dimensional stereolithography is used.
Resumen de: AU2024212880A1
An apparatus comprises a soft robotic arm and a three-dimensional (3D) bioprinter. The soft robotic arm has actuators for controlling movements of a distal end of the soft robotic arm. The 3D bioprinter is attached to the distal end of the soft robotic arm, and has a print nozzle and soft microtubule artificial muscles (SMAMs) for controlling movements of the print nozzle.
Resumen de: US2025248828A1
The Invention refers to a method for manufacturing a new prosthesis for a lower limb, the method comprising the following steps:a) Providing 3D-data of a prior inner surface of a prior socket and of ist position and its orientation relative to a component adapter, —b) Creating a 3D model of a prosthetic socket with an attachment area for a socket adapter, wherein the prosthetic socket has an inner surface based on the scanned prior inner surface and an outer surface, —c) Determining information about an orientation transmitter, —d) Manufacturing of the prosthetic socket based on the 3D model and providing the orientation transmitter based on the information, —e) Directly or indirectly connecting the manufactured socket to a component adapter by means of the orientation transmitter so that the position and orientation of the inner surface of the prosthetic socket relative to the position and orientation of the component adapter corresponds to the position and orientation of the prior inner surface of the prior socket to the component adapter.
Resumen de: US2025250522A1
A device for modelling physiological and pathophysiological states of the brain is provided. The device comprises a hydrogel with micropattern channels having a length, width and depth. The micropattern channels comprise cells selected from the group consisting of neurons, astrocytes, microglia, oligodendrocytes, neuronal organoids, cancer cells, cancer spheroids, brain tumoral cells and combinations thereof.
Resumen de: US2025252697A1
A method for fabricating a custom headwear for a subject is described. The method comprises generating a three-dimensional head data file for the subject and determining contour lines on the head; automatically generating a headwear data file. The method yet further comprises utilizing the headwear data file to generate a shape for a desired headwear, the shape having an interior configured to restrain growth of the head in first predetermined areas. Still further, the method comprises generating contour lines for the custom headwear.
Resumen de: US2025248902A1
The present invention relates to a curable composition for dental purposes. The invention is characterized in that the composition comprises core-shell impact modifiers and 0.1 to 10 wt. % of a binder based on long-chain mono-functional (meth)acrylic acid esters, wherein the ester group has a carbon chain with at least 3 carbon atoms. The invention also relates to the use of the composition as a dental material or a dental auxiliary material, to a dental product made of the composition, and to a method for producing the dental product.
Resumen de: WO2025163396A2
A system may include a donor supply sub-system configured to supply donor material to a donor substrate. The system may include a material transfer sub-system comprising a laser configured to illuminate the donor substrate via a transfer beam. The system may include an instrument head of a medical instrument configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.
Resumen de: WO2025163003A1
The invention relates to a method for adapting a composite medical shoe to a human foot (1). A pressure protection element (2) serves to relieve pressure from the human foot or parts thereof.
Resumen de: WO2025163465A1
The present invention provides a method and system for fabricating complex human tissues by integrating bio-electrospraying, cell electrospinning merged with 3D multi material microfluidic bioprinting, and future additions of magnetic and acoustic levitation technologies. The fabricated tissues serve as an alternative to animal testing in drug discovery processes, aiding in the prediction of human physiological responses to various drug compounds.
Resumen de: CN119789957A
The invention relates to a novel silicone foam obtained from a foamable, crosslinkable silicone composition, the invention relates to a composition comprising an organopolysiloxane having at least two silicon-bonded alkenyl groups per molecule, an organosilicon-containing compound having at least two and preferably at least three silicon-bonded hydrogen atoms per molecule, a hydrosilylation catalyst, at least one porogen as water, hydrogel or aqueous silicone emulsion, and at least one surfactant, at least one chemical blowing agent; and a linear polydimethylsiloxane.
Resumen de: WO2024069629A1
A 3D-printing support medium is provided herein, comprising hybrid calcium-alginate hydrogel particles and a dispersion medium, formulated by combining calcium-alginate and a soluble polymer distinct from alginate, and the dispersion medium contains a minimum of 2 mM gluconate. These hybrid hydrogel particles possess an average size ranging from 0.1 pm to 50 pm, with exceptional homogeneity characterized by a particle size distribution of less than 50% RSD, resulting in a substantially transparent medium to visible light. The support medium is provided in various forms, including drained particles and slurries with different volume ratios of hydrogel particles to the dispersion medium. The process of preparing this support medium involves forming, pulverizing, washing, and contacting the hybrid hydrogel particles with a gluconate solution, ensuring the presence of gluconate within the hydrogel matrix.
Nº publicación: EP4594104A1 06/08/2025
Solicitante:
ELKEM SILICONES FRANCE SAS [FR]
ELKEM SILICONES USA CORP [US]
Elkem Silicones France SAS,
Elkem Silicones USA Corp
Resumen de: CN120018951A
The present invention relates to a process for the post-treatment of a 3D printed silicone article, said process comprising coating the 3D printed silicone article with a crosslinkable silicone composition comprising a microfiller. The invention further relates to a crosslinkable silicone composition comprising a microfiller, and to the use thereof as a post-treatment composition for post-treating 3D printed silicone articles.
BOPI
Sede Electrónica
