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一种3D打印生物墨水及其制备方法和应用

Resumen de: CN120643748A

本发明提供一种3D打印生物墨水及其制备方法和应用。所述3D打印生物墨水包括如下组分：甲基丙烯酸酐化明胶、氧化透明质酸、羧甲基壳聚糖和2‑甲基丙烯酰氧乙基磷酸胆碱。本发明通过对3D打印生物墨水的具体组成进行设计，制备得到了打印性能好、力学强度好、电传导性能好、打印后细胞存活率高的3D打印生物墨水，进而制备得到了细胞‑支架相互作用较强的3D打印支架，可用于制备皮肤损伤修复材料。

光造型用树脂组合物

Resumen de: US2022371264A1

The present invention provides a resin composition for stereolithography that enables easy stereolithographical fabrication; and that can produce a cured object having desirable strain recovery, desirable toughness, and desirable water resistance. The present invention relates to a resin composition for stereolithography comprising a polymerizable compound (A) whose homopolymer has a glass transition temperature (Tg) of 37° C. or higher; and a photopolymerization initiator (B), and having a tan δ at 37° C. of 0.3 or less after cure.

三维光造型用固化性组合物及其制造方法、三维光造型物的制造方法以及牙科用修复物的制造方法

Resumen de: AU2024218051A1

The present invention provides a curable composition for three-dimensional stereolithography, the curable composition being used in a vat photopolymerization method and containing 100 parts by mass of a polymerizable monomer component (A), 40 parts by mass to 400 parts by mass of an inorganic filler (B) that is composed of a single kind or plural kinds of inorganic particulate matter, and 0.01 part by mass to 5 parts by mass of a photopolymerization initiator (C), wherein: 80% or more of all primary particles that constitute the inorganic filler (B) have a particle diameter of 0.05 µm to 5.0 µm; and a sample, which is formed of this curable composition for three-dimensional stereolithography and has a thickness of 0.5 mm, has a transmittance of 1.00% to 50.00% with respect to activation light. The present invention also provides a method for producing this curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic model and a method for producing a dental restoration, each using this curable composition for three-dimensional stereolithography.

微结构的增材制造

Resumen de: WO2024165390A1

The invention relates to a method for additive manufacturing of a microstructure (10) for selective transmission of X-ray or gamma-ray radiation. The method includes depositing (110) a layer of powder on a build plate or on a layer from at least one previous manufacturing step on the build plate, wherein the layer of powder comprises a high-Z material powder. Furthermore, the method includes selectively melting (120) and solidifying the powder to form septa wall structures (20) by scanning an electron beam in a spot sequence on the layer of powder to sequentially expose a plurality of spots (40) on the layer of powder to an electron beam spot. A size of the electron beam spot is at most 150 μm in diameter, preferably at most 75 μm in diameter, and more preferably at most 50 pm in diameter. The high-Z material powder comprises a high-Z material having an atomic number Z of at least 40, and preferably at least 70. The invention also relates to a microstructure for selective transmission of X-ray or gamma-ray radiation, which microstructure has been obtained by the method, and to an imaging component comprising such microstructures. The invention also relates to a method for manufacturing an imaging component.

一种3D打印多孔TC4合金接骨板以及制备方法

Resumen de: CN120624889A

本申请涉及医疗器械技术领域，具体公开了一种3D打印多孔TC4合金接骨板以及制备方法。一种3D打印多孔TC4合金接骨板，其包括如下原料：Fe、C、N、H、O、Al、V、余量为钛粉；所述3D打印多孔TC4合金接骨板为多孔结构，孔径为300‑600μm，孔隙率为60%‑75%，孔隙连通率＞95，且所述3D打印多孔TC4合金接骨板上设置有若干个固定孔。本申请所得到的3D打印多孔TC4合金接骨板的抗拉强度、断裂伸长率和疲劳极限最高可达1602MPa、30%和665MPa，具有较高的力学性能，改善了畸形矫正锁定接骨板无法适应复杂解剖结构，导致术后稳定性较差或畸形矫正角度丢失等问题。

一种集成式食品3D打印喷印机

Resumen de: CN120616173A

本发明公开了一种集成式食品3D打印喷印机，本发明涉及3D打印技术领域。包括安装在控制面板外壳前壁的控制面板、顶部观察门框架、前观察门框架、后部整体外壳，所述顶部观察门框架、前观察门框架、后部整体外壳相互组合安装构成机箱，通过设置装料罐加热盒装置，整体为夹层式结构中间用于放置硅橡胶加热板、温度传感器和压力传感器，使用硅橡胶加热板加热内部的物料装填罐，温度传感器实时检测温度，并传回数据便于实时调节加热的温度，压力传感器用于检测电推杆挤压出物料装填罐内物料时的压力，并传回数据用于精准控制电推杆的挤压力度，在外部左右两侧设计有磁力固定零件放置架，用于回收和放置时的固定。

一种带环喷码工装夹具

Resumen de: CN223327186U

本申请公开了一种带环喷码工装夹具，其包括底板、设置于所述底板顶部前侧的上模、设置于所述底板顶部后侧的下模，所述上模与所述下模相互对应，所述底板顶部还均匀固定设有若干定位板，若干所述定位板位于所述上模与所述下模之间，所述上模上均匀固定设有若干角码块，所述角码块位于所述定位板右侧，所述下模上均匀固定设有若干固定板，所述夹具通过调节所述固定板、所述角码块与所述定位板之间的间距来实现对不同规格所述带环的夹紧固定。

一种具有三维梯度结构的牙齿种植方法

Resumen de: CN120616817A

本发明涉及种植牙体自动模拟制备技术领域，具体公开了一种具有三维梯度结构的牙齿种植方法，通过口内扫描仪获取颌骨三维数据，建立种植牙体的梯度仿生结构；咬合力分析模块计算各区域应力分布，通过激光微织构形成拓扑梯度，基于颌骨三维数据生成具有力学适配性的梯度结构模型；金属打印形成基台和固位螺丝，进行激光表面处理，牙冠进行真空烧结处理；植体的内置槽内部设置电化学沉积纳米ZnO抗菌层，植体的内置槽内安装基台，基台上安装牙冠；种植牙体采用单体配装或者连桥配装，种植牙体连桥配装时，三个牙冠为整体成型结构；本发明减少医生手术打磨次数以及护理次数，提高牙齿种植效率，大大减少使用者的适应期，提高种植牙体的使用舒适性。

一种基于MRI重建的个性化3D打印面膜及其制备方法

Resumen de: CN120620652A

本发明公开了一种基于MRI重建的个性化3D打印面膜及其制备方法。该方法包括以下步骤：采用磁共振设备对人体面部进行扫描，得到人体面部MRI数据，根据人体面部MRI数据生成人体面部三维模型；以人体面部三维模型为基准，生成与面部轮廓完全贴合的立体模具；采用医学影像平台从人体面部MRI数据中提取出人体面部皮肤的生理参数，根据生理参数对人体面部皮肤的生理状态进行量化分析，得到量化分析结果；采用生物3D打印设备，以立体模具为载体，结合量化分析结果，进行3D打印，得到3D打印面膜。本发明制备的3D打印面膜能够与人体面部轮廓高度贴合，对不同面部区域的皮肤问题进行精准护理。

聚多巴胺修饰的明胶-海藻酸钠生物墨水及其制备和应用

Resumen de: CN120617616A

本申请提供用于聚多巴胺修饰的水凝胶，其包含：明胶和海藻酸钠形成的三维水凝胶骨架，其中，所述明胶和所述海藻酸钠未化学交联；以及结合于所述三维水凝胶骨架上的聚多巴胺颗粒。本申请还提供包含所述聚多巴胺修饰的水凝胶的生物墨水以及所述生物墨水在制备用于抗炎、促进伤口愈合或促血管化的3D打印支架的用途。

A BIORESORBABLE CARDIOVASCULAR STENT (BCS) AND ITS METHOD OF PREPARATION THEREOF

Resumen de: WO2025186835A1

The present invention discloses a bioresorbable cardiovascular stent (100). The bioresorbable cardiovascular stent (100) comprising at least one strut (104) (110) connecting the plurality of rhombus-shaped cells (102) in both the longitudinal directions and the circumferential directions and each strut (104) (110) provided with a consistent thickness (108) and width (106). The stent (100) maintains a uniform thickness (108) throughout its length, and featuring struts (104, 110) with consistent thickness (108). The stent (100) is manufactured by using a micro-injection molding process with a single sprue-less hot runner gate. The bioresorbable cardiovascular stent (100) is configured to maintain structural integrity, biocompatible properties, improve radial stiffness to (612 kPa/mm) and radial strength to (225 kPa).

一种拔牙创护板

Resumen de: CN223323622U

本实用新型提供一种拔牙创护板，涉及口腔医学技术领域，拔牙创护板包括护板主体，护板主体用于封堵牙槽窝，护板主体的两侧均设置有翼部，翼部向护板主体朝向牙槽窝的一侧延伸，一个翼部用于卡设于牙槽窝的颊侧牙龈，另一个翼部用于卡设于牙槽窝的舌侧牙龈。本实用新型实施例提供的拔牙创护板，可发挥物理屏蔽保护及压迫止血作用，可以在底部放置止血填塞类材料，也可以通过给药孔进行药物补充。该装置的应用有利于拔牙窝的愈合，减少患者止血失败、感染、干槽症等拔牙并发症的风险；且术后患者在进食及口腔卫生护理等过程中，持续隔离保护创口，能够大大改善患者拔牙术后的体验感；患者一般无需再次就诊，拔牙创口完全愈合后，取下护板即可。

一种多孔生物陶瓷、制备方法及其应用

Resumen de: CN120622908A

本申请提供的多孔生物陶瓷、制备方法及其应用，将氧化铝浆料与造孔剂混合得到混合浆料；采用DLP 3D打印以逐层投影的方式，使混合浆料发生光固化反应，逐层打印积累成型以得到陶瓷坯体；对陶瓷坯体进行高温处理，以得到多孔生物陶瓷，本申请通过氧化铝浆料复合造孔剂与DLP 3D打印技术，保证材料内部无贯通孔，维持高致密度与力学强度，解决现有技术中表面性能与力学性能难以兼顾的问题；且在高固含量氧化铝陶瓷表面构建离散多孔结构，实现表面粗糙度与的精准调控，直接形成表面离散孔洞，省略复杂的后处理过程；通过烧结工艺，控制整体烧结收缩率，提升复杂结构的成型精度，满足规模化生产需求，可应用于骨组织工程支架及牙齿修复材料。

APPARATUS AND METHOD FOR 3D PRINTING

Resumen de: WO2025186544A1

A printhead for 3D printing of solid-dosage-forms, said printhead having an integrated powder dispenser or an integrated peristaltic pump, wherein said solid-dosage-form comprises at least one active-ingredient and at least one excipient. Related 3D printers, solid-dosage-form printing apparatuses and associated methods are also disclosed.

一种3D打印功能增强的聚醚醚酮复合材料及其制备方法

Resumen de: CN120617629A

本发明涉及3D打印用生物材料技术领域，特别涉及一种3D打印功能增强的聚醚醚酮复合材料及其制备方法。一种3D打印功能增强的聚醚醚酮复合材料，该材料包括如下质量份数的原料：聚醚醚酮75‑85份，改性生物活性材料5‑10份，碳纳米管1‑3份，有机成核剂0.5‑2份，生物调节剂0.1‑1份，抗菌剂0.1‑1份；所述改性生物活性材料为改性羟基磷灰石和/或改性磷酸三钙。该基本配方实现了多功能组分的协同作用，通过精心配比的聚醚醚酮、改性生物活性材料、碳纳米管等成分，解决了现有PEEK材料在生物活性和结晶性能方面的不足，并提供了优异的力学性能和生物相容性。

BIOMATERIAL COMPOSITION COMPRISING GRAPHENE OXIDE-COMPRISING HYDROGEL AND DECM MATERIAL FOR 3D (BIO)PRINTING

Resumen de: WO2025188203A1

The invention relates to a composition for three-dimensional printing comprising a hydrogel comprising: a. graphene oxide, b.methacrylated derivatives of biopolymers, and c. radical polymerisation photoinitiator

用于经由装载有API的组织穿透器递送药物的装置和方法

Resumen de: WO2024163829A1

A drug delivery device includes at least one tissue penetrating member configured to embed into tissue, the at least one tissue penetrating member including: a plurality of cavities, and at least one payload comprising at least one active pharmaceutical ingredient (API), the at least one payload loaded into the plurality of cavities so that the at least one API can be absorbed into the tissue when the at least one tissue penetrating member is embedded in the tissue, wherein a ratio of a surface area of the plurality of cavities to a volume of the plurality of cavities is at least 0.5:1

歯列矯正器具のためのトランスファー装置及び関連する製造方法

Resumen de: CN119855708A

A method of manufacturing a transfer device includes providing a physical physical model having a shape corresponding to a positive shape of a patient's dental arch and one or more stent assemblies each including a lifting mechanism body releasably connectable to an orthodontic appliance. A transfer device may be formed over the physical entity model, wherein a transfer denture represents a negative replica of at least a portion of the entity model. The transfer device may be used to place the appliance on a patient's dental arch, after which the appliance may be detached from the lifting mechanism body and bonded to the associated tooth.

An implantable medical device

Resumen de: AU2025220886A1

AN IMPLANTABLE MEDICAL DEVICE A component including: a body having one or more surfaces with a contour formed to be substantially complementary to an anatomical surface of a specific patient; the body adapted to securably engage with a component-engaging part to form at least part of an implantable medical device, wherein: the one or more surfaces are substantially configured to evenly engage with the anatomical surface of the specific patient when the component is secured to the component-engaging part and the medical device implanted in the patient; and the body is at least in part manufactured by additive manufacturing. AN IMPLANTABLE MEDICAL DEVICE A component including: a body having one or more surfaces with a contour formed to be substantially complementary to an anatomical surface of a specific patient; the body adapted to securably engage with a component-engaging part to form at least part of an implantable medical device, wherein: the one or more surfaces are substantially configured to evenly engage with the anatomical surface of the specific patient when the component is secured to the component-engaging part and the medical device implanted in the patient; and the body is at least in part manufactured by additive manufacturing. ug u g c o m p o n e n t i n c l u d i n g : a b o d y h a v i n g o n e o r m o r e s u r f a c e s w i t h a c o n t o u r f o r m e d t o b e s u b s t a n t i a l l y c o m p l e m e n t a r y t o a n a n a t o m i c a l s u r f a c e

Additive Manufacturing of Porous Coatings Separate From Substrate

Resumen de: US2025281273A1

An implant is produced by fabricating first and second layers. The first layer of repeated and truncated building units is fused together to define pores. The second layer of repeated and truncated building units are fused together to define pores and fused onto the first layer of truncated building units. The first and the second layers form at least part of a porous portion of the implant. The formed porous portion is attached onto a base portion of an implant. The truncated building units of each of the first and the second layers are in the form of spatially overlapping three-dimensional shapes.

ORODISPERSIVE DOSAGE FORMS CONTAINING DROXIDOPA

Resumen de: US2025281441A1

A rapidly-orodispersible tablet containing a porous, bound powder matrix containing droxidopa. The bound matrix contains an acidulant, particularly citric acid, to delay, reduce, or inhibit the coloration of droxidopa during stress storage conditions, and suppress the effect of glycerin on the coloration of droxidopa-containing tablets. The tablet can be dividable along a functional seam printed into the bound powder matrix, to divide the tablet into sub-dosage units of the same mass of droxidopa.

PROSTHESIS COVER AND METHOD FOR PRODUCING A PROSTHESIS COVER

Resumen de: US2025281308A1

The invention relates to a prosthesis cover having at least one fastening device (20) for securing the prosthesis cover (1) to a prosthesis component (2), and a flexible main body (10) which has an inner side (11) facing the prosthesis component (2) in the applied state and an outer side (12) opposite the inner side (11), on which outer side the at least one fastening device (20) is arranged, wherein at least one structural element (30) protruding from the outer side (12) is applied to the outer side (12) in an additive manufacturing process.

SYSTEM AND METHODS FOR TREATING A 3D PRINTED PROSTHETIC LINER

Resumen de: US2025281310A1

A 3D printed prosthetic liner adapted to provide an interface between a residual limb and a prosthetic socket, specifically a prosthetic liner manufactured using a 3D printing device, the surface of which being treated with one or more applications of a casting resin, and preferably a urethane-based casting resin forming a treated prosthetic liner having enhanced strength and pliability.

Systems and Methods for Utilizing Partially Digested Cartilage Matrix for Chondral Defects

Resumen de: US2025281674A1

An exemplary embodiment of the present disclosure provides a method of utilizing partially digested cartilage for chondral defects, the method comprising: obtaining cartilage; mincing the cartilage into a plurality of pieces of cartilage; partially digesting the plurality of pieces of cartilage in a digesting mixture to form partially digested cartilage; and encapsulating the partially digested cartilage.

Method for Preparing Skull Flap by Photo-Curing 3D Printing

Nº publicación: US2025281669A1 11/09/2025

Solicitante:

BEIJING TIANTAN HOSPITAL CAPITAL MEDICAL UNIV [CN]
Beijing Tiantan Hospital, Capital Medical University

Resumen de: US2025281669A1

Provided is a method for preparing a skull flap by photo-curing 3D (three dimensions) printing, including the following steps: (1) constructing a 3D printing model: generating a corresponding 3D model based on a cranial scan data of a patient; (2) preparing a 3D printing ink: weighing a photo-crosslinking hydrogel, mixing the photo-crosslinking hydrogel and a nanoclay solution to obtain a mixed system, and then adding a photoinitiator and a photoresist into the mixed system to obtain the 3D printing ink; and (3) conducting photo-curing 3D printing: subjecting the 3D printing ink to ultrasonic mixing, then filling into an ink tank of a photo-curing 3D printer, transferring the corresponding 3D model into the photo-curing 3D printer, and subjecting the corresponding 3D model to printing to obtain the skull flap; wherein the nanoclay solution comprises an extracellular matrix component.