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168
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Última actualización
17/09/2025 [07:24:00]
Resultados 25 a 50 de 168
Resumen de: US2025281670A1
Provided is a three dimensional (3D) printing photo-curing composition suitable for skull repair. The 3D printing photo-curing composition suitable for skull repair includes the following components: nanoclay; a photo-crosslinking hydrogel; at least one photoinitiator; and at least one photoresist.
Resumen de: US2025281680A1
Disclosed herein is a biomaterial and a method of use thereof for treating a condition. A biomaterial of the disclosure can be, for example, a surgical article. Implantation of a biomaterial disclosed herein into a subject can treat, for example, cancer.
Resumen de: US2025282974A1
Provided is a photocurable resin composition used for producing a three-dimensional formed article by a liquid tank photopolymerization method, the photocurable resin composition containing (A) a radically polymerizable monomer, (B) an inorganic filler, (C) a photopolymerization initiator, (D) an activated light absorbent, (E) a polymerization inhibitor, and (F) a chain transfer agent, wherein: at least 90 mass % of the component (A) has two or more (meth)acryloyl groups in the molecule, and is composed of a polyfunctional (meth)acrylate-based radically polymerizable monomer (a) having 5 to 25 atoms constituting a main chain of a divalent group interposed between the two or more (meth)acryloyl groups; and the component (a) is composed of a polyfunctional monomer a1 having a specific group such as a urethane group and a polyfunctional monomer a2 other than the polyfunctional monomer a1. Also provided is a method for producing a three-dimensional photoformed article by using the photocurable resin composition.
Resumen de: US2025283019A1
Disclosed herein are various bioreactor devices that mimic the mammalian joint. The bioreactor device includes a series of bioreactor chambers that contain different components of the joint, such as bone, cartilage, synovium, and ligament, and which are integrated with neural processes to better recapitulate physiological conditions, including joint pain. At least two different nutrient fluid circulation systems connect subsets of the bioreactor chambers to differentially supply nutrient fluids at concentrations optimized for the tissue that the fluid nourishes. The disclosed bioreactor devices enable interrogation of the interplay between the peripheral nervous system and joint tissues. By recording activity in sensory neurons, joint integrity as well as therapeutic efficacy can be monitored in real time.
Resumen de: US2025283035A1
The bioink disclosed herein includes one or more cells, a carrier material, and microspheres. The microspheres can include one or more biodegradable polymers and one or more compounds, such as a morphogenic compound. The methods disclosed herein can include three-dimensional bioprinting. Additional methods disclosed herein include producing functional tissue.
Resumen de: MX2025009432A
The invention relates to an arrangement for manufacturing a plurality of orthodontic appliances (1) in parallel, comprising an additive printing machine (2) comprising a build platform (4) and configured for additively manufacturing a plurality of teeth models (9) in parallel, a plurality of plates (6) each configured for teeth model printing by the additive printing machine (2), whereby each plate (6) comprises a unique machine-readable identifier (13) and each plate is detachable and precisely fixed to the build platform (4), and a thermoforming machine (10) configured for thermoforming a thermoformable material (11) over the plurality of teeth models (9) for receiving the plurality of orthodontic appliances (1).
Resumen de: JP7738146B1
【課題】良質な装具を効率よく製造できるようにする。【解決手段】装具使用者の身体における装具装着部位の形状を示す個人形状情報を取得する情報取得部と、個人形状情報に基づいて前記装具使用者が使用する装具の形状を示す個別装具情報を生成する情報生成部と、装具の形状を示す装具形状情報の入力に応じて装具を製造するペレット方式の３Ｄプリンタによる装具製造装置に前記個別装具情報を用いた装具の製造を行わせる製造指示部とを備える装具製造システムである。【選択図】図１
Resumen de: JP2025132775A
【課題】硬化物に曲げ強度を付与することができるチオウレタン（メタ）アクリレート化合物を提供する。【解決手段】２つの下記式（Ｘ）で表される結合と、２つのウレタン結合と、２つの（メタ）アクリロイル基と、を含む、チオウレタン（メタ）アクリレート化合物。式（Ｘ）中、２つの＊は、それぞれ、結合位置である。JPEG2025132775000027.jpg2371【選択図】なし
Resumen de: NL2040421A
A scaffold composite, and a preparation method and use thereof are provided, belonging to the technical field of medical implant materials. A method for preparing a scaffold composite is provided, including: mixing a graphene oxide (GO) dispersion and a polylactic acid (PLA) dispersion, and subjecting a resulting mixed solution to curing and melt extrusion in sequence to obtain a 3-dimensional (3D)— printable GO/PLA composite wire; subjecting the 3D—printable GO/PLA composite wire to 3D printing to obtain a scaffold; and annealing the scaffold to obtain the scaffold composite. The scaffold composite prepared by the preparation method not only exhibits no obvious toxicity to osteoblasts, but also can promote cell proliferation and differentiation. Furthermore, the scaffold composite exhibits a strong ability to induce the formation of new bone, and the osseointegration is more rapid and solid.
Resumen de: EP4613237A2
Systems and methods for securing artificial teeth to a dental prosthetic base with a gradient polymer are disclosed herein. An example system includes one or more processors and a memory communicatively coupled with a 3D printing device and the one or more processors. The memory stores a set of instructions thereon that, when executed by the one or more processors, cause the one or more processors to: generate a print file representative of a polymeric dental prosthesis, the print file including (i) a first material, (ii) a second material that does not chemically bond with the first material, and (iii) a gradient transition zone bonding the first material to the second material that is a gradient polymer of the first material and the second material; and print, via the 3D printing device, the polymeric dental prosthesis based on the print file.
Resumen de: EP4613484A2
Threaded sacro-iliac joint stabilization (e.g., fusion, fixation) implants and methods of implantation and manufacture. Some implants include a threaded distal region, an optionally threaded central region, and an optionally threaded proximal region. The distal, central, and proximal regions have lengths such that when the implant is laterally implanted across a SI joint, the distal region can be positioned in a sacrum, the central region can be positioned across an SI-joint, and the proximal region can be positioned in an ilium.
Resumen de: CN120201970A
Provided herein are medical devices and methods for treating bone fractures. The medical device includes a body, a stent within the body, and means for concentrating bone growth throughout the body. The device is designed to minimize shear stresses on the distal tip and to distribute micromotion to promote bone ingrowth. The stent may include a three-periodic minimal curved surface (TPMS) having a cubic repeating pattern defining walls within the stent, and the TPMS may be helically wound about a central axis of the device. The device may also contain a biological agent and contain an autologous product. In some embodiments, the medical device is a bone screw or pedicle screw designed to reduce common problems such as screw loosening, screw disengagement, and shaft breakage. The method of treatment involves implanting the medical device into a bone of a patient to aid in fracture healing.
Resumen de: CN120187366A
Provided herein are medical devices and methods for treating bone fractures. The medical device includes a body having a proximal end and a distal tip, the body housing a stent having porous structures distributed in a proximal grid and a distal grid. The device includes an upper lumen in fluid communication with a first opening at the proximal end, and a lower lumen in fluid communication with a second opening at the proximal end. The device is configured to support independent delivery of cement and cells to the mesh. In some embodiments, the device is a bone screw having a thickened head-neck junction designed to reduce the likelihood of rod breakage during installation. The method includes implanting the device into a bone of a patient, thereby providing an innovative method for fracture treatment.
Resumen de: WO2024097682A1
An indirect bonding (IDB) tray that can be positioned over a single tooth of a patient. The IDB tray can include a well to receive an orthodontic bracket therein. The IDB tray can be 3D printed with a rigid photopolymer material and a soft photopolymer material. The soft photopolymer material may be disposed on a gingival portion of the IDB tray such that the soft photopolymer material can be positioned proximate the gums of the patient to improve patient comfort and/or accommodate gum remodeling due to tooth movement. The soft photopolymer material may be disposed around an inner periphery of the well to facilitate bracket insertion and/or release from the well. The IDB tray can include separation indicia indicating where the IDB tray can be sectioned. The IDB tray can include long axis lines to indicate proper orientation of the IDB tray on a patient's one or more teeth.
Resumen de: BE1032411A1
De huidige uitvinding biedt, onder andere, een werkwijze voor het ontwerpen van een steunzool, omvattende het ontvangen van een meting van een voetzool welke verband houdt met druk, genoemde meting bij voorkeur verkregen middels het belasten van een meetoppervlak; het ontvangen van een zoolprofiel; het bepalen, op basis van genoemde meting, van een of meer anatomische zones; het bepalen, op basis van genoemde anatomische zones, van een voetprofiel omvattende een hoofdas; het bepalen, minstens op basis van genoemd voetprofiel en genoemde anatomische zones, van een interpolerend oppervlak; het aligneren van het interpolerend oppervlak met het zoolprofiel, voor het verkrijgen van een gealigneerd 3D-profiel; het genereren, op basis van genoemd gealigneerd 3D-profiel, van een instructie voor het produceren van de steunzool; waarbij genoemd bepalen van het interpolerend oppervlak gebeurt volgens een 3D-karakterisatie volgens respectieve posities (y1, y2) op genoemde hoofdas; waarbij genoemd bepalen van het interpolerend oppervlak het berekenen omvat, op basis van genoemd voetprofiel en genoemde anatomische zones, van een veelheid van telkens ten minste twee ankercoördinaten (d0-d3) liggend in een respectieve dwardoorsnede overeenstemmend met genoemde respectieve posities (y1, y2), en het berekenen, op basis van genoemde ten minste twee ankercoördinaten (d0-d3), van een interpolerend oppervlak.
Resumen de: WO2024094275A1
The present invention relates to a method for interactively designing via an implant design platform an artificial joint implant for hip arthroplasty and corresponding broaching and osteotomy guide apparatuses. The proposed implant design platform reconstructs the anatomy of the patient's pelvic and femoral bones in a 3D digital environment, and accordingly develops a patient-specific femoral implant stem as well as patient-specific surgical tools broach/rasp, osteotomy guide) used in total hip arthroplasty. The patient-specific femoral implant stem developed may be optimized to ensure optimum mechanical performance for the patient, employing complex internal lattices that minimize stress shielding and advanced trabecular surfaces to promote osseointegration.
Resumen de: CN120605117A
本发明涉及医疗器械领域，具体涉及一种数字个性化牙弓支架，包括与牙列形状相匹配的支架本体，所述支架本体呈波浪形，支架本体上设有牵引挂件和用于将支架本体固定在牙列上的固定部，固定部包括固位环和用于连接固位环和支架本体的连接件，固位环位于相邻两牙根之间且用于安装定位钉，其制作方法，包括对患者上下颌牙列进行扫描，及齿科锥形束CT检查；将三维数据导入三维设计软件中构建牙、牙龈、颌骨三维模型，设计植入钛钉的固位环以及支架曲线，并在支架曲线上设计牵引挂件和用于连接固位环的连接件，通过3D打印得个性化数字牙弓支架。通过实施本方案以提升该牙弓支架与患者口腔的适配精度及安装效率。
Resumen de: US2025100811A1
An apparatus for processing containers having a transport device which transports the containers to be processed along a predefined transport path has at least one processing device which is configured to process a container in a predefined manner, wherein the apparatus has a movement device, having at least one first guide cam and at least one guide roller which is configured to roll relative to the guide cam. The apparatus also has a detection device which is configured to detect at least one measurement value which is characteristic of a running property of the guide roller relative to the guide cam, and an evaluation device which is configured to evaluate this detected measurement value taking into account at least one further operating value characteristic of the operation of the apparatus.
Resumen de: AU2023410422A1
The present invention relates to a crosslinkable polymer composition comprising at least one calcium phosphate, at least one biocompatible and biodegradable organic polymer or one of its precursors, and Zn-ZnO core-shell particles, to a biomaterial obtainable by photopolymerization of such a crosslinkable polymer composition, to a process for preparing such a composition and such a biomaterial, and to the use of such a biomaterial for various applications in the field of health.
Resumen de: TW202449426A
Ophthalmic lenses and method of manufacturing ophthalmic lenses are disclosed.
Resumen de: CN120605442A
本发明涉及生物医疗技术领域，具体涉及一种具有力学传感功能的伤口治疗微针贴片。该微针贴片包括：柔性基底；设置在上述柔性基底上的微针阵列，上述微针阵列包括多个微针；至少一个上述微针上设有空腔，上述空腔内填充有液态金属。由于微针上设有空腔且空腔内填充有液态金属，当微针插入皮肤后，皮肤组织张力变化导致空腔形变，导致液态金属截面积改变，从而可以通过测量液态金属电阻变化信号分析力学特征。
Resumen de: CN120585491A
本发明公开了基于分形几何结构的植入体及其制备方法，所公开的基于分形几何结构的植入体包括植入体本体，植入体本体上设有与生物体组织缺损部位适配的表面，所述与生物体组织缺损部位适配的表面为分形几何结构；所述分形几何结构由若干一级分形各自经过多级分形而形成，所述一级分形为多边形；且由单个一级分形经过多级分形形成的单个高级分形与植入体本体表面面连接。本发明解决了现有植入体表面结构设计和加工受技术限制等原因，导致表面微结构设计与加工难以统一，微结构控形难，影响后续骨结合功效和远期种植体成功率等问题。
Resumen de: AU2023403078A1
The present invention provides articles for the improved healing of wounds, preferably burn wounds. In some preferred embodiments, the article is a matrix formed from a mixture of two or more polysaccharides, the matrix comprising an active ingredient which is an extract from differentiable cells.
Resumen de: US2025276492A1
The disclosure relates to a method for three dimensional (3D) printing an object, the method comprising the steps of:—providing a print job, the print job comprising a representation of the object,—dividing the representation of the object in one or more bodies;—for each body, define settings for printing the respective body, wherein settings for at least one body include filling the body with a porous infill structure;—slicing the representation of the object in a number of slices,—the step of slicing comprising, for the body to be filled with the porous infill structure:—defining for every slice an infill area that is to be filled with the porous infill structure;—defining a circumference of the infill area;—adapting the porous infill structure to the circumference; and—filling the infill area with the adapted infill structure.
Nº publicación: CN120586156A 05/09/2025
Solicitante:
上海大学
Resumen de: CN120586156A
本发明提供了一种缓释药物的界面增强型再生骨支架及其制备方法和应用，属于骨组织工程技术领域。本发明以聚己内酯和羟基磷灰石和作为再生骨支架的基体成分，具有与宿主骨匹配的机械强度和良好的生物相容性；本发明在再生骨支架基体表面和内部孔隙负载聚多巴胺涂层，易于进行表面功能化修饰，聚多巴胺涂层中的邻苯二酚结构能够与MOFs中的金属离子进行配位结合，从而降低MOFs颗粒的脱落率，使MOFs颗粒分布均匀和稳定；本发明使用MOFs颗粒负载杜仲提取物，安全无毒，杜仲提取物包封在MOFs颗粒中，能够提高杜仲提取物的稳定性，实现更好的药物释放效果和促骨再生效果。
BOPI
Sede Electrónica
