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195
resultados
Última actualización
17/07/2025 [07:15:00]
Resultados 175 a 195 de 195
Resumen de: US2025197789A1
A reinforcing and scaling construction for a bioprinted tissue model, which comprises a casing and sealing bioink, the casing comprising an inner module comprising a casing base (1) and a perforated cover (2), and an outer module comprising a container (3) comprising technological valves (5), an outer cover (4) and plugs (6) for technological valves (5). The invention also relates to a method for assembling the reinforcing and sealing construction.
Resumen de: US2025197659A1
There is provided a bioink for bioprinting a porous three-dimensional hydrogel structure, the bioink comprising an aqueous medium; and granular crosslinkable hydrogel precursor particles suspended in the aqueous medium, wherein the granular crosslinkable hydrogel precursor particles have an average size of from 100 microns to 500 microns, and wherein under suitable crosslinking conditions, the granular crosslinkable hydrogel precursor particles crosslink and adhere to one another, to form the porous three-dimensional hydrogel structure having pore diameters in the range of from 20 microns to 200 microns. There is also provided a method of forming a porous three-dimensional hydrogel structure using the bioink disclosed herein and a porous three-dimensional hydrogel structure obtained from said method.
Resumen de: WO2025124741A1
The instant invention relates to a powder layer for use in 3D binder jetting printing comprising a hydrolyzed and functionalized starch compound. It also relates to a process for 3D binder jetting printing using the same. It also relates to products, in particular solid dosage forms, obtained thereof by 3D binder jetting printing.
Resumen de: US2025195196A1
The development of devices for a functional cure for diabetes by mimicking native pancreatic tissue for production of all pancreatic hormones. A physiologically and mechanically biocompatible artificial pancreas, wherein the pancreas comprises a combination of a PVA hydrogel combined with cells selected from the group consisting of islets; clusters of islets; Beta cells, and combinations of islets and Beta cells. The bioartificial pancreas contains vascular grafts therein or thereon a wall of the pancreas so that said grafts are an integral part of the wall of the bioartificial pancreas. The grafts can be anasmotized to living blood vessels in the body.
Resumen de: WO2025127798A1
The present invention relates to a strontium-emitting 3D printing scaffold for promoting bone cartilage regeneration and a method for manufacturing same. The scaffold continuously maintains the emission of a triad of ions including strontium (Sr), silicate (Si), and calcium (Ca) to promote cell migration to a damaged site, and has a hierarchical porous structure, and thus enhances tissue regeneration by increasing cell engraftment, immune regulation, and angiogenesis, and exhibits an excellent anti-inflammatory effect. Therefore, the scaffold can be effectively used for the regeneration of damaged bone and cartilage tissue.
Resumen de: WO2025127906A1
The present invention relates to 3D-printed anatomical models with flexible photopolymerisable coatings that allow the production of solid hollow models, which may be geometrically highly complex, with high anatomical fidelity and high optical translucency. The piece of the invention mainly acquires these advantageous technical features as a result of the use of coatings that can be photopolymerised by means of step-growth mechanisms or hybrid polymer reactions, as is achieved with thiol-ene chemistry, also called click chemistry or thiol-Michael additions, which may be mediated by free radicals or catalysts.
Resumen de: WO2025127247A1
A method for manufacturing a patient-customized wound dressing integrated with microneedles, and a patient-customized wound dressing integrated with microneedles, manufactured through same, are provided. A wound dressing is manufactured through 3D bioprinting by using a photopolymerizable biocompatible biodegradable bioink, and then microneedles are formed on the wound dressing through two-photon polymerization (2PP) printing by using the photopolymerizable biocompatible biodegradable bioink, and thus the patient-customized wound dressing integrated with microneedles is manufactured.
Resumen de: US2025195191A1
The present disclosure provides an apparatus for post-curing an article, as well as a system, methods, and post-cured articles. The apparatus includes a housing, a chamber disposed in the housing, at least two light emitting diodes (LEDs) disposed within the housing, and a user interface disposed on an exterior of the housing. The chamber is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber includes a material transparent to actinic radiation and light from the LEDs enters the chamber from more than one direction. The user interface includes a display and program switches configured to adjust at least three operational parameters of the apparatus. The apparatus further includes a vacuum pump operatively coupled to the chamber. The system includes the apparatus and an article. An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content. A method of post-curing an article includes obtaining an article, placing the article in an apparatus, inputting a post-cure program or accessing a saved post-cure program through the user interface, and running the post-cure program. The post-cure program includes light intensity provided by a light source and length of time of light provided by the light source, plus a delay time between initiation of light provided by the light source and initiation of vacuum pulled by the vacuum pump and/or a delay time between initiation of vacuum pulled
Resumen de: US2025195179A1
There is described a medical implant comprising: a bone engaging portion comprising: an outer portion comprising or consisting of a conformal lattice structure; an inner portion comprising a cavity or a lattice structure; a helical thread extending around and recessed into or protruding from an outer surface of said bone engaging portion, said helical thread being configured to facilitate screwing of said bone engaging portion into bone.
Resumen de: US2025195208A1
The invention relates to an ear implant for improving or restoring the hearing ability in the event of defects in the area of the ossicles of the ear or posterior wall of the auditory canal, said implant consisting of lithium disilicate glass ceramic having a molar ratio of SiO2 to Li2O of 2 to 3, wherein the glass ceramic material being doped and stabilized with P2O5 and ZrO2, as well as a method for the production of the implant and the use of lithium disilicate glass ceramics in ear implants.
Resumen de: US2025195099A1
The invention relates to a method of manufacturing an inner tube for a surgical cutting device comprisinga. an outer tube having an outer tube head portion at a distal end of the outer tube;b. said outer tube head portion having an outer tube window; whereinc. the inner tube can be rotatably disposed in the outer tube;d. an inner tube head portion is provided at a distal end of the inner tube; whereine. at least one cutting edge is formed on the inner tube head portion, which cutting edge is moved out of an interior of the outer tube when the inner tube is rotated through the outer tube window and is moved back into the interior of the outer tube when the inner tube is further rotated through the outer tube window; the method comprising the following steps:f. providing an inner tube middle portion having a distal end;g. forming the inner tube head portion at the distal end of the inner tube middle portion by an additive manufacturing process to obtain the inner tube.
Resumen de: US2025195175A1
The present disclosure provides polymerizable composition that can produce desirable stain resistant polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.
Resumen de: US2025197658A1
This disclosure provides stable polymerizable resin compositions comprising one or more antioxidant stabilizers to prevent undesired polymerization and/or oxidation of polymerizable components as well as undesired depletion of photoinitiators in the polymerizable resin composition. Such polymerizable resin compositions can be used to produce polymeric materials with properties suitable for use in various mechanical appliances, such as orthodontic appliances.
Resumen de: US2025195723A1
Embodiments relate to granular hydrogel bioinks with preserved interconnected porosity for extrusion bioprinting and methods of use and making thereof. The granular hydrogel bioinks comprise hydrogel particles and materials/methods to reversibly connect them to each other without compromising void spaces. These materials/methods include but are not limited to nanoparticles, wherein the nanoparticles are absorbed onto the microgels and wherein the nanoparticles are configured to allow for electrostatic bonding of the microgels. These materials/methods can also include reversible functional groups, selected from guest-host groups and/or dynamic covalent bond forming groups.
Resumen de: WO2024033402A1
The invention relates to a maxillary modeller (2) intended to be worn, in a service position, on a dental arch of a user in order to modify the shape of the palate, the maxillary modeller being one-piece and removable and comprising: - a central palatal portion (22) configured to be in contact with the user's palate when the maxillary modeller is in the service position; and - a first and a second dental portion (24; 26) each comprising at least one, preferably multiple cavities configured to receive teeth of the user when the maxillary modeller is in the service position, the first and second dental portions extending on either side of the central palatal portion, the central palatal portion being configured so as to exert on the palate, in the service position, forces suitable for modifying the shape thereof.
Resumen de: AU2023323651A1
Provided is an implantable tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin, wherein the chitin is embedded in the biocompatible organic polymer. Also provided is a composition for 3D printing, the composition comprising at least one biocompatible organic polymer and chitin that may be partially deacetylated, wherein the chitin is embedded within the biocompatible organic polymer. Further provided is a method of promoting tissue formation, comprising implanting a tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin at a site in need of regenerative bone tissue formation.
Resumen de: US12331272B1
An ultra-high-cell-density multicellular tissue lifting bioprinting device assisted by oblique incident bulk wave and a printing method therefor are provided, and the printing device includes a printing liquid tank, a printing platform, a light source and an oblique incident bulk wave chip; the printing liquid tank contains a printing liquid which is a mixture of cells and a photocurable bioink; the printing platform is arranged horizontally and extends into the printing liquid tank to come into contact with the printing liquid; the printing platform is capable of going up and down; the light source is arranged under the printing liquid tank, and light enters the printing liquid tank; the oblique incident bulk wave chip is a piezoelectric transducer arranged obliquely; the piezoelectric transducer is arranged under the printing liquid tank and tilted relative to the horizontal plane to generate an oblique incident bulk wave acoustic field in the printing liquid.
Resumen de: KR20250088264A
본 발명은 생분해성의 합성 고분자 재질로 이루어지는 중간부 시트와; 상기 중간부 시트와 동일한 크기를 가지는 생분해성의 천연 고분자 재질로 이루어지는 상, 하부 시트;를 포함하고, 상기 중간부 시트는 생분해성의 합성 고분자 재질로 3D 프린팅하여 제조한 미세 구조를 가진 시트 또는 전기방사하여 제조되어 미세 섬유가 무정형하게 적층되어 이루어지고, 상기 상, 하 및 중간부 시트는 별도의 접합이 없는 삼층 구조의 무접합 보철용 고분자 스캐폴드 및 이의 제조방법을 제공하고자 한다.
Resumen de: CN120154756A
本发明公开了一种用于修复骨缺损的DAT‑海藻酸钠3D多孔支架、制备方法及应用，本发明提供的DAT‑海藻酸钠3D多孔支架展现了良好的生物学性能和成骨诱导能力，在骨缺损修复中的应用潜力巨大。
Nº publicación: CN222983250U 17/06/2025
Solicitante:
中国医学科学院整形外科医院
Resumen de: CN222983250U
本实用新型公开了一种用于耳朵术后形态保持的支撑件，包括：内贴合层，外层桁架，所述外层桁架呈罩体形状，所述外层桁架的一侧边缘与所述内贴合层连接；支撑单元，所述支撑单元的数量为多个，所述支撑单元为弹性部件，所述支撑单元设置在所述内贴合层和所述外层桁架之间，所述支撑单元的一端与所述内贴合层连接，所述外层桁架的内侧与所述支撑单元的另一端连接，本实用新型可以提升保持器的舒适性以及支撑强度。
BOPI
Sede Electrónica
