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SURGICAL INSTRUMENT PORT FOR VAGINAL NATURAL ORIFICE TRANSLUMINAL ENDOSCOPIC SURGERY

Resumen de: US20260232352A1

A surgical instrument port is designed for use in vaginal natural orifice transluminal endoscopic surgery, made of a disposable, biocompatible and elastic material, and allows multiple surgical instruments and endoscopes to simultaneously have access to the desired body cavity.

COMPOSITIONS AND METHODS FOR THREE-DIMENSIONAL (3D) BIOPRINTING

Resumen de: US20260232869A1

0000 As a three-dimensional (3D) bioprinting technique, digital light processing (DLP) has become popular due to its capability to provide high-throughput and high-resolution constructs with precise chemical and biological factor distributions. However, despite the advancements in DLP technology, several hurdles remain, including phototoxicity, extensive printing time, and the limited portfolio of biocompatible/photo-cross-Jinkable materials. Herein, a novel DLP-based 3D-bioprinting technology′ called photopolymerization of orderly-extruded multi-materials (POEM) has been developed and fully characterized. The utility of the POEM technique for rapid and high-resolution 3D-printing of multi-material, multi-layer, and cell-laden structures is demonstrated. The printed configurations showed high cell viability (−80%) and metabolic activity′ for more than five days. The light-based POEM technique described herein enables the fabrication of 3D-cell-laden structures in a multi-material and multi-layer printing manner in biocompatible/photo-cross-linkable materials essential to construct complex heterogeneous tissues/organs.

MULTIVALENT POLYESTER BASED POLYURETHANE ACRYLATE OR METHACRYLATE OLIGOMERS FORMULATED WITH DIFFERENT REACTIVE DILUENTS

Resumen de: US20260232541A1

The present disclosure provides novel oligomers and polymerizable compositions comprising the same. Further provided herein are methods of producing polymers, polymer coatings, and devices. Also provided herein are methods of using polymer materials and polymer materials fabricated via additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances.

VASCULAR GRAFT ASSEMBLIES, VASCULAR GRAFT SYSTEMS, AND METHODS OF USE THEREOF

Resumen de: US20260232426A1

Reinforced external graft support assemblies and methods of manufacture and implantation are provided herein. In particular, graft support assemblies are composed of single or multilayer sheaths designed to provide mechanical support to vascular conduits during cardiovascular bypass surgery. Graft sheath systems may be fabricated using 3D printing techniques with biocompatible materials incorporate surgical design considerations such as mechanical strength, flexibility, porosity, and the ability to be tailored to specific anatomical structures. External graft sheaths may include one or more layers of various biomaterials to produce customized biomechanical properties including varied time courses of degradation. Furthermore, these customizable features may incorporate standardized designs or be tailored for individual patients depending on medical and surgical history, or other pertinent geometric attributes measured in pre-operative medical imaging. These methods protect vascular conduits, particularly venous grafts, from adverse remodeling and graft failure, thereby providing precision medicine solutions to cardiovascular bypass surgery.

GENERATION OF ARTIFICIAL INTRA-OPERATIVE SENSOR DATA

Resumen de: US20260232380A1

0000 A computer-implemented method of generating artificial intra-operative sensor data usable in training an artificial intelligence (AI) module is presented. The method comprises the following steps: providing a clinical data structure describing several clinical states of a clinical procedure and defining transitions between said several clinical states allowing for different paths of the clinical procedure (step S1); providing at least one geometrical model for modelling procedural scenes in one or more of said clinical states of said clinical procedure (step S2), wherein the at least one geometrical model comprises a plurality of geometrical model parameters and boundary conditions for said geometrical model parameters; wherein the geometrical model parameters describe said procedural scenes in said clinical states of said clinical procedure, wherein a particular combination of values of the geometrical model parameters defines a particular procedural scene of a clinical state of said clinical procedure; the method further comprising the steps defining an individual path of the clinical procedure by selecting at least one transition between a first and a second clinical state of the clinical data structure (step S3); providing, as input for the geometrical model, a set of values of the geometrical model parameters of the at least one geometrical model for said first and said second clinical states of the defined individual path thereby modelling a first individual pro

TECHNIQUES FOR AUTOMATED MARKING OF DENTAL APPLIANCES

Resumen de: US20260233338A1

The present disclosure discusses techniques for marking a dental appliance. A dental model and dental appliance are positioned onto a conveyor tray, which is transported to a scan station. The dental model and conveyor tray each include an identifying code. The scan station includes a camera and barcode reader to read the identifying codes on the dental model and conveyor tray, and these codes are associated with one another. The conveyor tray then moves to a marking station where a barcode reader reads the code on the conveyor tray, and then marks the dental appliance with the appropriate marking.

TECHNIQUES FOR IDENTIFYING REPRESENTATIVE PPG PULSES

Resumen de: US20260232212A1

0000 Methods, systems, and devices for identifying representative photoplethysmogram (PPG) pulses are described. A method may include acquiring a first set of PPG pulses from a user via a wearable device. The method may include comparing a set of morphological features of the first set of PPG pulses, and determining one or more PPG profiles for the user, where the one or more PPG profiles each include a set of morphological value ranges for the set of morphological features. The method may include acquiring a second set of PPG pulses from the user via the wearable device, and determining that one or more PPG pulses from the second set of PPG pulses match the one or more PPG profiles. The method may include determining one or more physiological metrics associated with the user based on the one or more PPG pulses matching the one or more PPG profiles.

WEARABLE DEVICE FOR PHYSIOLOGICAL MONITORING

Resumen de: US20260232263A1

The present invention relates to a modular wearable device for monitoring a user's health parameters. The present invention provides a better aid in remote monitoring, thus, improving the quality of life, aiding in recovery and improving the overall quantifiability of a person's health over intervals longer than prior possible. The present invention discloses a garment worn over the torso, within which multiple sensors are integrated in selective locations in order to best suit the needs of sensing/monitoring the functioning of the internal organs using non-invasive approaches. The present invention provides long-term monitoring of a patient's health parameters. The present invention provides a “smart-wearable” device with sensors, data processors, communication devices and their associated communication and energy circuitry.

DEVICES, SYSTEMS, AND METHODS FOR VIRTUAL STAINING

Resumen de: US20260232197A1

0000 The disclosure herein provides methods, systems, and devices for virtually staining biological tissue for enhanced visualization without use of an actual dye or tag by detecting how each pixel of an unstained tissue image changes in waveform after staining with a certain dye(s) and/or tag(s) or other transformation under a certain electromagnetic radiation source, developing a virtual staining transform based on such detection, and applying such virtual staining transform to an unstained biological tissue to virtually stain the tissue.

SUCTION DEVICE AND INFORMATION PROCESSING METHOD

Resumen de: US20260232930A1

0000 Provided is a suction device provided with: a housing section having an inner space and an opening; a first detection unit which detects the state of the inner space; a second detection unit which detects information associated with the state of the suction device; and a control unit that performs, on the basis of a detection result obtained by the second detection unit, the control of the switching of the mode of the first detection unit to an operation mode or a stop mode and the determination whether or not the control of the operation of the suction device is performed in accordance with a detection value detected by the first detection unit when the mode of the first detection unit is in the operation mode.

Acute Stressors Detection Using a Wearable Device

Resumen de: US20260237521A1

0000 A method of acute stressor detection using a wearable device includes obtaining sensor data for an individual from one or more sensors of the wearable device while the wearable device is worn, the sensor data including physiological data. A processor determines one or more physiological parameters, including one or more heart rate related parameters, from the sensor data and determines data associated with at least one lifestyle event, including a sleep event or an exercise event. The processor detects a physiological deviation event indicative of reduced adaptive capacity based on the one or more physiological parameters, determines at least one candidate acute stressor for the physiological deviation event based on the lifestyle-event data and data associated with the physiological deviation event, and outputs an indication of the at least one candidate acute stressor to the individual.

GOAL SETTING AND TRACKING FOR NEUROMODULATION TREATMENT

Resumen de: US20260233005A1

0000 Systems, devices, and methods are disclosed for computer-assisted goal setting and tracking with respect to neuromodulation device treatment. A digital health system includes a user-interface device to receive a user input about a personalized objective of neuromodulation treatment or an intended manner of using the neuromodulation device by the patient. The user input can be in forms of text, voice, or other unstructured or unclassified data formats. A controller circuit can process the user input using analytical methods including natural language processing to generate a personalized treatment and device usage goal, and track the progress toward the personalized treatment and device usage goal using patient state information. The tracked progress may be presented to the patient, or be used to initiate or adjust a neuromodulation therapy.

METHOD, DEVICE, AND SYSTEM FOR PROVIDING MEDICAL AUGMENTED REALITY IMAGE USING ARTIFICIAL INTELLIGENCE

Resumen de: US20260237111A1

Provided are a method and device for providing a medical augmented reality image using artificial intelligence, and more particularly, provided are a method and device for providing a medical augmented reality image by changing a medical image of a patient captured before an operation according to posture information of the patient during the operation using an artificial intelligence model and matching the changed medical image to a body image of the patient to be output to medical staff during the operation.

ARTIFICIAL INTELLIGENCE-BASED SYSTEMS AND METHODS FOR AUTOMATIC MEASUREMENTS FOR PRE-PROCEDURAL PLANNING

Resumen de: US20260232382A1

0000 A computer implemented method to automatically measure structural features of anatomies using an automatic measurement system, the method includes receiving medical images of the anatomies. The method includes detecting landmarks of the anatomies based on the medical images using an artificial intelligence (AI)-based model and constructing an anatomical structural model of the anatomies based on the detected landmarks. The method includes making quantifying measurements of selected structural features of the anatomical structural model and generating a report including the quantifying measurements.

METHODS AND DEVICES FOR SECURE COMMUNICATION WITH AND OPERATION OF AN IMPLANT

Resumen de: US20260237380A1

A method of teaching a voice-controlled medical implant to recognize a voice command, the method comprising: inputting a first audio training phrase to the medical implant, when the medical implant is implanted in the body of the patient, creating a transfer function, the transfer function being based on the first audio training phrase, wherein the transfer function is configured to adjust the amplitude of at least one frequency of audio received at the medical device for enhancing audio received at the medical implant to facilitate detection of voice commands, inputting a second audio training phrase to the medical implant, the second audio training phrase comprising the voice command, the voice command comprising an instruction for the control of the medical implant, using the transfer function for generating an enhanced second audio training phrase in the medical implant, and associating the enhanced second audio training phrase with the instruction for the control of the medical implant.

INTERVERTEBRAL CAGE WITH INTEGRATED TRANSMITTER

Resumen de: US20260237475A1

0000 A medical implant can comprise a physical structure configured to secure the medical implant within a body of a patient, a proximity communication component physically coupled to the physical structure, and a memory operatively coupled to the proximity communication component. The memory can store a private key, wherein the memory is configured to provide the private key through the proximity communication component to an external device for enabling the external device to access one or more electronic medical records associated with a patient that is implanted with the implant from a distributed blockchain ledger of electronic medical records.

PATIENT REQUEST SYSTEM HAVING PATIENT FALLS RISK NOTIFICATION AND CAREGIVER NOTES ACCESS

Resumen de: US20260232282A1

0000 st system includes a tablet computer that configured for entry of patient requests. The tablet computer is configured to display a first menu corresponding to basic request categories for a patient. The tablet computer is configured to display a second menu that corresponds to specific patient requests falling under the basic request category selected by the patient using the first menu. A server is configured to receive a specific patient request made by the patient. A notification device is configured to display the specific patient request to a caregiver. A patient request method is also disclosed.

REAL TIME IMAGE GUIDED PORTABLE ROBOTIC INTERVENTION SYSTEM

Resumen de: US20260232394A1

0000 An image-guided robotic intervention system ("IGRIS") may be used to perform medical procedures on patients. IGRIS provides a real-time view of patient anatomy, as well as an intended target or targets for the procedures, software that allows a user to plan an approach or trajectory path using either the image or the robotic device, software that allows a user to convert a series of 2D images into a 3D volume, and localizes the 3D volume with respect to real-time images during the procedure. IGRIS may include sensors to estimate pose of the imaging device relative to the patient to improve the performance of that software with respect to runtime, robustness, and accuracy.

APPARATUS AND METHOD FOR AUTOMATIC ULTRASOUND SEGMENTATION FOR VISUALIZATION AND MEASUREMENT

Resumen de: US20260232296A1

A system and method for performing ultrasound scans is provided. One embodiment of the ultrasonographic system acquires sonogram information from a series of ultrasonic scans of a human subject. The series of ultrasound scans are taken over a portion of interest on the human subject which has their underlying bone structure or other ultrasound discernable organ that is under examination. The data from the series of scans are synthesized into a single data file that corresponds to a three-dimensional (3D) image and/or 3D model of the underlying bone structure or organ of the examined human subject.

Patient Ventilator Asynchrony Detection

Resumen de: US20260237511A1

A decision support tool is provided for identifying and assisting clinicians with patient ventilator asynchrony. The information used to make the identification may include data from a patient's ventilator including the volume, flow, and pressure associated with that ventilator. At least some of this information may be used to compute one or more features for a time series of the data received for the patient. These features may be used in connection with heuristic rules and machine learning algorithms to identify instances of patient ventilator asynchrony. Based on the identification, one or more intervening actions may be initiated to reduce the impact of patient ventilator asynchrony.

DEVICE FOR MEASUREMENT COLLECTION AND TREATMENT

Resumen de: US20260232222A1

One or more wearable devices, computing devices, systems and/or methods are provided. In an example, a device is provided. The device may include one or more accelerometers configured to generate measurement data based upon movement associated with a body part of a person. The device may include a communication device configured to transmit a message comprising the measurement data to a computing device. The device may be operable within an imaging region of an imaging machine.

EXCIPIENT COMPOSITION FOR THE PREPARATION OF AMORPHOUS SOLID DISPERSONS/SOLUTIONS

Resumen de: US20260232594A1

0000 The invention provides an excipient composition for the preparation of an amorphous solid dispersion or amorphous solid solution suitable for, i.a., 3D printing of immediate release tablets. The excipient composition comprises: a) 8-20% by weight of the excipient composition of sugar alcohol, and b) 80-92% by weight of the excipient composition of a polymer blend, the polymer blend comprising a first polymer component and a second polymer component in a weight ratio of 1:0.55-1:1.75, the first polymer component being a copolymer of 1-vinyl-2-pyrrolidone and vinyl acetate, and the second polymer component being polyethylene glycol-polyvinyl alcohol graft copolymer.

対話型生理学的モニタリングシステム

Resumen de: WO2025024317A2

A user question can be classified into topics and mapped to appropriate static and/or dynamic content related to the user and/or question. This data can then be collectively provided to a large language model in order to generate a suitable response, which may include, for example, summarization, rephrasing, analysis, and the like, as well as executable code for dynamically presenting content of the response to the user and/or functionally adapting a user platform according to the response.

POLYCAPROLACTONE HAVING IMPROVED SLS 3D-PRINTING SINTERING PROPERTIES

Resumen de: WO2025073518A1

The present invention refers to a compound particle for 3D printing obtained by hot melt extruding 50 to 90 wt.-% at least one polycaprolactone based polymer; 10 to 50 wt.-% of at least one filler; and optionally up to 5 wt.-% of at least one additive into pellets, wherein the total weight of the components is 100 wt.-%, and thereafter milling the pellets to obtain the compound particle. Furthermore, the present invention refers to a composition for 3D printing comprising a) 94 to 99 wt.-% of at least one compound particle according to the present invention; b) 1 to 6 wt.-% of at least one filler; and c) optionally up to 5 wt.-% of at least one additive; wherein the total weight of a) to c) is 100 wt.-%. Moreover, the present invention refers to a 3D printing method comprising the compound particle or the composition according to the present invention, the article obtained by the 3D printing method and its use as a substitute for bones or a scaffold for broken bones.

DEVICE AND METHOD FOR ESTIMATING BIO-AGE USING BIOMARKER

Nº publicación: EP4789603A1 12/08/2026

Solicitante:

SEOUL NAT UNIV HOSPITAL [KR]
Seoul National University Hospital

Resumen de: EP4789603A1

0001 Disclosed are a device and method for estimating bio-age according to an embodiment. The device for estimating bio-age according to an embodiment comprises: one or more processors; and one or more memories storing instructions executed by the one or more processors. The one or more processors are configured to: extract one or more biomarkers by inputting input data including biological signals of a user to a first model; and estimate the bio-age of the user on the basis of a second model modeled using the one or more biomarkers.