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195
resultados
Última actualización
17/07/2025 [07:15:00]
Resultados 125 a 150 de 195
Resumen de: US2025205392A1
Embodiments relate to a device and/or method for vascularization, which can also be used to enhance regenerating tissues. The method comprises inducing surgical micropuncture, in which small perforations are created using a microscale needle in a wall of a target vessel. The method further comprises guiding microvascular development using granular and/or porous scaffolds, which are formed by converting materials, including polymers, to microparticles or porous constructs and subsequently assembling the microparticles or directly using the porous constructs by implanting on the target vessel and/or in the target tissue. The granular and/or porous scaffolds can also be formed on target tissues in situ.
Resumen de: US2025205965A1
An orthodontic aligner that is formed of a three-dimensional printing composition includes: 10 to 80% by mass of (meth)acrylate having a urethane bond; 10 to 80% by mass of (meth)acrylate free from a urethane bond; 3 to 30% by mass of a polyurethane powder; and 0.01 to 10% by mass of a photopolymerization initiator. A viscosity of the composition is 200 to 3,000 mPa·s.
Resumen de: WO2025133728A1
The present invention relates to an orally administered formulation comprising caffeine as an active ingredient and having a drug-release controlling property, and a method for preparing same by using 3D printing and relates to a pharmaceutical composition and a food composition, of the formulation, for preventing or treating jet lag, and a composition to be applied to a 3D printer.
Resumen de: WO2025134771A1
Problem To provide a novel derivative of rhamnan sulfate, a novel ink composition for 3D printers containing the same, a novel composition having FGF binding promoting activity and the like. Solution The problem can be solved by a rhamnan sulfate derivative having a phenolic hydroxy group linked thereto, a novel ink composition for 3D printers derived from rhamnan sulfate containing and a rhamnan sulfate derivative having a methacrylic acid linked thereto, and a composition for promoting FGF binding containing the same.
Resumen de: MX2024014918A
The present invention relates to a medical device manufactured using the additive manufacturing process (3D printing). It is a medical device used preferably as a bone graft composed of a porous structure based on bioceramics based on β-tricalcium phosphate (β-TCP) or hydroxyapatite, which may or not contain nanostructures in its composition, for example: carbon nanostructures (graphene, graphene oxide, reduced graphene oxide, carbon nanotubes, etc.) and, in preferred embodiments, stem cells and polymeric membrane. Also, the present invention relates to the use of this device as a bone graft and the process of preparing this device.
Resumen de: AU2023403078A1
The present invention provides articles for the improved healing of wounds, preferably burn wounds. In some preferred embodiments, the article is a matrix formed from a mixture of two or more polysaccharides, the matrix comprising an active ingredient which is an extract from differentiable cells.
Resumen de: DE102023135732A1
Die Erfindung betrifft eine radikalisch polymerisierbare Verbindung, dargestellt durch eine Struktur der Formel 1:PG1-Sp1- OC (O) NH-K-NHC (O) O-Arn-OC (O) NH-K-NHC (O) O-Sp2-PG2(Formel 1) ,sowie eine radikalisch polymerisierbare Zusammensetzung, die Verwendung der radikalisch polymerisierbaren Verbindung oder der radikalisch polymerisierbaren Zusammensetzung zur Herstellung eines polymerisierbaren Dentalmaterials und ein ausgehärtetes Dentalmaterial.
Resumen de: WO2025137128A1
The present disclosure provides polymerizable composition that can produce desirable stain resistant polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.
Resumen de: WO2025131708A1
The invention relates to a radically polymerisable compound represented by a structure of formula 1: PG1-Sp1-OC(O)NH-K-NHC(O)O-Arn-OC(O)NH-K-NHC(O)O-Sp2-PG2 ( formula 1), and to a radically polymerisable composition, to the use of the radically polymerisable compound or the radically polymerisable composition for producing a polymerisable dental material and to a cured dental material.
Resumen de: GB2636639A
A moulded article 104 comprises a surface, particularly a child-safe product suitable for babies or infants, the article comprises first 110 and second 120 volumes of material compression moulded together to form a moulded surface, the first volume having a first colour and the second volume having a second colour different from the first, and wherein the moulded surface includes a third volume of material co-moulded with the first and second materials. The first volume of material is selectively deposited in the mould by drip moulding or by a three-dimensional printing process, wherein the first and second areas of different colours define a predetermined image, text or symbol on the moulded surface of the article. The first component may have an internal surface, pre-formed with one or more undulations (142, fig. 3) into which the material of the second component is pressed to form a co-extensive internal bonded surface therebetween. The materials may be food-grade silicone, preferably containing antimicrobial silver powder and/or another biocide. A method of moulding an article is also provided.
Resumen de: EP4574086A1
The present invention is characterized by the following steps:Generating and storing multiple dental images sequentially configured according to each correction stage (S01), Displaying any one of the multiple dental images from the previous step (S02), After displaying the dental image in step S02, setting and displaying a reference line in the transverse direction for each tooth to determine the overall shape of the transparent orthodontic aligner (S03), Setting a cutting line corresponding to the end portion of the orthodontic aligner, which is spaced a certain distance from the gum direction based on the reference line, and displaying it on the dental image from step S02 (S04), Displaying the first treatment image, which shows the transparent orthodontic aligner partially covering both the upper and lower dental arches, based on the cutting line set in step S04(S05).
Resumen de: US2024051246A1
Methods for manufacturing objects are provided herein. In some embodiments, a method includes receiving a dental appliance formed using an additive manufacturing process, the dental appliance including a plurality of appliance portions. The method can include identifying, based on sensor data, a location of a subset of the appliance portions on the dental appliance. The method can further include applying energy to a subset of the appliance portions to selectively modify one or more material properties of the subset of the appliance portions.
Resumen de: US2024059927A1
The present disclosure provides a range of printed materials comprising discrete layers or segment with distinct compositions, and which can collectively lend to high levels of strength, toughness, and break resistance, and these printed materials may contain thin, ductile layers interspersed between thicker, harder layers, thus in printing such materials, the present disclosure further provides a range of compositions and methods, including low viscosity, air stable, and rapidly solutions amenable to thin layer inkjet printing.
Resumen de: WO2024038000A1
The present invention relates to a process for the preparation of a solid pharmaceutical administration form comprising an amorphous solid dispersion using a 3D printing process. The process is a printing process that allows the production of a solid pharmaceutical solid administration form comprising an amorphous solid dispersion in an easy and flexible manner and the possibility to achieve fast disintegrating dosage forms with high drug loads.
Resumen de: KR20250093878A
실크 피브로인은 천연재료로써 매우 유용한 재료이다. 그러나, 기계적인 강도가 약하고, 더욱이 3D 프링팅 잉크로 사용하기에는 너무 물렁물렁한 문제가 있어왔다. 이러한 문제들을 해결하기 위하여 기존의 기술들은 가교제를 사용하여 실크피브로인을 폴리머화하여 사용하고 있다. 이렇게 가교제를 사용하면 물리적인 성질과 3D 프린터의 인쇄성이 증가하는 장점은 있으나, 생체 내에서 발생하는 항원항체 반응 및 생체 조직과의 이질성이 높은 문제가 있어왔다. 본 출원 발명은 이러한 문제를 해결하고자 가교제를 사용하지 않고, 실크 피브로인을 3D 프린팅 잉크로 사용할 수 있는 다음의 발명의 구성을 제공한다. 실크 피브로인; 및 플루로닉F127(DA-PF 127);을 증류수에 혼합하여 용해시킨 혼합용액을 구비하고, 상기 혼합용액에 글리세롤을 혼합하여 37℃에서 겔화되는 것을 특징으로 하는 3D 바이오프린팅을 위한 실크 피브로인 기반 감열성 바이오잉크를 제공한다. 상기와 같은 발명의 구성에 의하여 기존의 가교제를 사용하지 않고 글리세롤만을 사용하여 37℃에서 겔화되어 생체 내에서 사용할 수 있는 3D 바이오 프린팅을 위한 바이오 잉크를 제공하는 효과가 있는 발명이다.
Resumen de: KR20250093879A
세포 증식을 위한 안정적인 미세 환경의 제공을 위하여 기공 크기가 300μm보다 큰 지지가 필요하며, 기존의 동물들의 뼈 분말에서 CaCO3를 활용하는 기술에서 해양 생물 중에 CaCO3를 많이 보유하고 있는 생물을 발굴하여 이를 적극 활용할 필요가 있다. 본 출원 발명은 상기와 같은 문제를 해결하고자, Na2HPO4(Sodium hydrogen phosphate), PEG, 히알루론산(Hyaluronic acid), 젖산 용액(Lactic acid)은 각각의 원료 분말에 2차 증류수를 첨가한 후 6시간동안 균질화하여 제조하는 용액제조단계; 및 상기 Na2HPO4는 4 (weight/volume(%)), PEG 15 (weight/volume(%)), 히알루론산 1 (weight/volume(%)), 젖산 용액 2 (weight/volume(%))을 양을 혼합하여 용액을 준비하고, 인산칼슘 시멘트(CPC)는 β-TCP 및 hydroxyapatite 및 DCPA 및 CaCO3와cockle shell(꼬막껍질분말)의 혼합물을 사용하며, 인산칼슘 시멘트(CPC)의 조성은 상기 β-TCP는 60 (weight/volume(%)) 및 hydroxyapatite는 4 (weight/volume(%)) 및 DCPA는 26 (weight/volume(%)) 및 CaCO3와 cockle shell 혼합물은 10 (weight/volume(%))으로 구성되는 것을 특징으로 하는 뼈 재생을 위한 꼬막 껍질의 CaCO3를 이용한 3D프린팅잉크를 제공한다. 본 출원 발명의 상기와 같은 구성에 의하여 인공뼈를 구성하는 CaCO3가 풍부한 새로운 원료를 이용하여 3D 프린터를 사용하여 필요한 크기와 형태
Resumen de: LU509511B1
The invention discloses a simple 3D printing batch rats fixator, which comprises a fixation plate which is divided into a plurality of fixing areas; the fixing area includes: fixing columns, which are arranged at the four corners of the fixing area and are fixedly connected with the fixation plate; a head fixing ring, which is arranged between the top two fixing columns and fixedly connected to the top surface of the fixation plate; neck fixing holes, which are arranged in pairs and are symmetrical about the axis of the head fixing ring; trunk fixing holes, which are arranged in pairs and symmetrical with respect to the axis of the head fixing ring, are located at the side of the neck fixing hole far away from the head fixing ring; the neck fixing hole, the trunk fixing hole and the fixing columns are all provided with binding structures (Fig.1)
Resumen de: AU2025202950A1
The present disclosure provides a surgical implant device, including: a solid surface; and a lattice structure disposed adjacent to the solid surface, wherein the lattice structure includes a first plurality of struts that define a first plurality of voids adjacent to the solid surface and a second plurality of struts that define a second plurality of voids remote from the solid surface. The surgical implant device may also include one or more screw hole regions and/or a needle-populated porous surface disposed adjacent to the solid surface opposite the lattice structure. Fig 1 10,16 12 14b 14c14
Resumen de: WO2024098119A1
A detachable printhead for a bioprinter is disclosed, the detachable printhead comprising a body, removably attachable to a fixed portion of the bioprinter; a dispensing system, supported by the body; one or more reservoirs, for holding one or more biomaterials, in fluid communication with the dispensing system, supported by the body; and a coupling for attaching to the fixed portion of the bioprinter, the coupling including an interface for operating the dispensing system.
Resumen de: KR20250092409A
본 발명은 DLP 방식의 바이오 3D 프린터를 사용하여 세포가 함유된 도관이 매립된 인공 자궁내막 구조체 및 이의 제조 방법에 관한 것으로, 본 발명에 따른 인공 자궁내막 구조체는, 광가교성 하이드로겔 전구체에 자궁내막 기질세포, 자궁내막 줄기세포, 혈관내피세포가 혼합된 서로 다른 바이오 잉크를 제조한 후, 다중재료 바이오 DLP 3D 프린팅을 통해 제조될 수 있으며, 자궁내막 줄기세포가 포함된 제1영역; 상기 제1영역과 직접 접하도록 연결되며, 자궁내막 기질세포가 포함된 제2영역; 및 상기 제1영역과 제2영역을 동시에 관통하고 내벽에 혈관내피세포가 포함된 중공관 형태의 제3영역;을 포함한다
Resumen de: US12340541B1
A system and method for producing color calibrated videos using a calibration slate are provided. A video of a subject is recorded with a calibration slate appearing in at least one frame of the video. The calibration slate includes printed colors that can be compared against standard colors associated with the slate to color calibrate the video. Once at least one frame of the video has been color calibrated, calibrated colors of the calibrated frame may then be utilized for color calibration of additional frames of the video.
Resumen de: AU2023371661A1
Provided herein are medical devices and methods for treating bone fractures. The medical device comprises a body, a scaffold within the body, and a means for focusing bone growth throughout the body. The device is designed to minimize shear stresses on a distal tip and distribute micromotion to encourage bony ingrowth. The scaffold may include a triply periodic minimal surface (TPMS) with a cubic repeating pattern defining walls within the scaffold, and the TPMS may be helically wrapped around a central axis of the device. The device may also house biologic agents and accommodate an autologous product. In some embodiments, the medical device is a bone screw or a pedicle screw, designed to reduce common issues such as screw loosening, screw backout, and rod breakage. The method of treatment involves implanting the medical device into a patient's bone to aid fracture healing.
Resumen de: US2024091906A1
Systems and methods for processing additively manufactured objects are described herein. In some embodiments, for example, a system includes a controller configured to provide one or more control signals; a heater coupled to the controller, where the heater comprises one or more heating elements arranged to heat a blasting medium in response to the one or more control signals; a chamber coupled to the controller, where the chamber comprises an agitatable drum shaped to receive a plurality of additively manufactured objects, and to agitate the plurality of additively manufactured objects in response to the one or more control signals; and an applicator coupled to the controller, where the applicator comprises a nozzle operative to direct, in response to the one or more control signals, a plurality of thermally conductive particles in the blasting medium toward the plurality of additively manufactured objects within the agitatable drum.
Resumen de: CN120189550A
本发明属于骨修复材料技术领域，公开了一种缺氧诱导血管化功能的3D打印人工骨及其制备方法与应用，一种缺氧诱导血管化功能的3D打印人工骨，在人工骨表面设置二级孔隙结构，所述二级孔隙结构与人工骨孔隙连通并均匀分布在人工骨表面，所述二级孔隙结构为半封闭结构。本发明通过构建开口小内腔大的半封闭孔结构，在结构空间限制下，此人工骨的孔内部逐渐形成缺氧微环境，聚集的细胞产生缺氧诱导因子HIF‑1α，通过缺氧诱导信号通路诱导和促进血管生长。此3D打印人工骨无需添加药物，减少了加工成本和避免了药物副作用，通过内部半封闭结构设计实现缺氧诱导的机理加速血管化，促进骨组织再生，改善了3D打印人工骨的血管化成骨功能。
Nº publicación: CN120189554A 24/06/2025
Solicitante:
湖南工程学院
Resumen de: CN120189554A
本发明公开了一种纳米硅‑石墨烯协同增强的锌基骨植入物的制备方法，包括如下操作步骤：S1、制备稳定的氧化石墨烯悬浮液；S2、制备硅悬浮液；S3、制备氧化石墨烯‑纳米硅混合粉末再通过热还原反应得到石墨烯‑碳化硅‑纳米硅复合粉末；S4、制备锌/石墨烯‑碳化硅‑纳米硅混合粉末；S5、以锌/石墨烯‑碳化硅‑纳米硅混合粉末为原料，在保护气氛下，采用选择性激光熔化工艺制备得到锌基骨植入物；本发明还提供一种采用上述制备方法制得的锌基骨植入物。本发明可显著改善锌基骨植入物的力学性能，制备得到的锌基骨植入物具有较优异的生物活性。
BOPI
Sede Electrónica
