Alerta

RAMAN SPECTROSCOPY-BASED NON-INVASIVE GLUCOSE METER

Resumen de: WO2025161630A1

A Raman spectroscopy-based non-invasive glucose meter, comprising a light source module (110), a dichroic mirror (130), a lens module (150), an optical filter (191), and a photoelectric spectral measurement module (170). The light source module (110), the photoelectric spectral measurement module (170), and the lens module (150) are all arranged to correspond to the dichroic mirror (130). The optical filter (191) is disposed on a light-incident side of the photoelectric spectral measurement module (170) to filter out short-wavelength excitation light, and the photoelectric spectral measurement module (170) obtains spectral information by changing the refractive index in its own material.

DIABETES MANAGEMENT SYSTEM

Resumen de: US2025249170A1

A variety of location-based and/or proximity-based features related to diabetes management systems can be used to improve maintenance compliance and/or to provide important information to PWD designated assistance entities (e.g., family, friends, givers, HCPs, emergency medicine providers) under certain conditions. In some cases, a user's location can be tracked or determined to trigger and/or time alerts about upcoming maintenance tasks in a way that will increase the likelihood that the PWD will immediately perform the designated maintenance task. In some cases, methods, devices, and systems provided herein can use proximity to non-paired mobile computing devices to deliver data to PWD designated assistance entities.

VOICE-BASED METHOD AND SYSTEM FOR MANAGEMENT OF TYPE 2 DIABETES

Resumen de: US2025248667A1

An artificially intelligent, voice-based method for prescribing, managing and administering at least one medication for management of type 2 diabetes to a patient. Aspects of the present disclosure provide for a system and method for configuring one or more clinical algorithms according to one or more clinical protocols to configure a conversational AI model. The conversational AI model is configured to drive a conversational AI agent configured to facilitate a plurality of multi-turn conversational interactions between a patient user and the conversational agent to enable automated initiation and titration of one or more diabetes medications for the patient.

VOICE-BASED METHOD AND SYSTEM FOR MANAGEMENT OF TYPE 2 DIABETES

Resumen de: US2025248666A1

An artificially intelligent, voice-based method for prescribing, managing and administering at least one medication for management of type 2 diabetes to a patient. Aspects of the present disclosure provide for a system and method for configuring one or more clinical algorithms according to one or more clinical protocols to configure a conversational AI model. The conversational AI model is configured to drive a conversational AI agent configured to facilitate a plurality of multi-turn conversational interactions between a patient user and the conversational agent to enable automated initiation and titration of one or more diabetes medications for the patient.

ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS

Resumen de: US2025248633A1

Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.

IMPLANT APPARATUS FOR CONTINUOUS GLUCOSE MONITOR

Resumen de: US2025248627A1

Provided is an implant apparatus for a continuous glucose monitor. The implant apparatus includes a housing assembly and a driving assembly disposed in the housing assembly. The housing assembly includes an outer housing. The outer housing has an opening at an end of the outer housing. The driving assembly has a locked state in which the driving assembly is fixed relative to the outer housing and a triggered state in which the driving assembly is movable towards the opening. The implant apparatus further includes a trigger. The outer housing includes a guiding channel located at a side wall of the outer housing and extending towards the opening. The trigger is movable along the guiding channel towards the opening and has a first position and a second position relative to the outer housing, to enable the driving assembly to switch from the locked state to the triggered state.

Systems, devices, and methods for dual analyte sensors

Resumen de: CN120418886A

An analyte monitoring system and method for an on-body sensor control device may have the ability to sense two or more analytes of a patient, the sensor control device comprising a processor and a memory, there are instructions for determining various machine states and outputs based on time-dependent sensor data for each analyte. The status and output may include: alarm conditions for one or more analytes; consulting a message; a correction of the analyte state estimate; indication of failure of the sensor control device, failure of the insulin delivery device, drug dose calculation; or analyzing the report. Examples of systems and methods for dual analytes including glucose and ketones are described. Data may be transmitted from the sensor control device to the reader device for output to a user.

SYSTEMS, DEVICES, AND METHODS FOR WELLNESS MONITORING WITH PHYSIOLOGICAL SENSORS

Resumen de: MX2025008037A

Systems and methods for monitoring glucose variability are described. Data indicative of glucose levels of the subject is received. A first glucose metric is determined in a first time period. A second glucose metric is determined in a second time period. A difference between the second and first glucose metrics are determined. The difference is compared to a threshold. A first indicator is displayed if the difference does not exceed the threshold and a second indicator is displayed if the difference exceeds the threshold. In some embodiments, the indicator is one of a balanced state or a steady state and the second indicator is one of an unbalanced state, an unsteady state, a not steady state, or a spiky state.

Synchronous monitoring system and method for pressure and microcirculation of diabetic foot and risk assessment method

Resumen de: CN120392071A

The invention provides a diabetic foot pressure and microcirculation synchronous monitoring system and method and a risk assessment method, and the system comprises a flexible pressure sensing layer, a laser Doppler module, a temperature monitoring module, a humidity monitoring module and a data processing unit. The flexible pressure sensing layer, the laser Doppler module, the temperature monitoring module and the humidity monitoring module are respectively in signal connection with the data processing unit; the data processing unit is connected with a user terminal. A data fusion model is constructed, data integration is enhanced, a synchronous monitoring system comprising a flexible pressure sensing layer, a laser Doppler module, a data processing unit and a user terminal is established, a laser probe is embedded into the insole at an inclination angle, and the signal receiving efficiency is optimized; foot temperature and humidity measurement is added, early infection is recognized, and the influence of the blood vessel state and temperature and humidity changes on foot fungi is evaluated; an ulcer risk grading algorithm based on pressure-blood flow coupling analysis is designed, the monitoring efficiency is improved, and personalized early warning suggestions can be provided; the structure is simple and wearing is convenient and comfortable.

Chronic disease risk early warning system and method based on artificial intelligence

Resumen de: CN120413011A

The invention provides a chronic disease risk early warning system and method based on artificial intelligence. The method comprises the following steps: acquiring historical monitoring information of a diabetic patient; determining development trends of different disease course stages through historical monitoring information, and performing trend evolution based on all the development trends to obtain evolution characteristics of each disease course stage; determining the risk contribution degree of each health index to the chronic disease risk according to the linear correlation among different health indexes, and determining a risk monitoring model of the target patient through all the risk contribution degrees; performing confidence adjustment on the chronic disease risk in the risk monitoring model according to each evolution feature, and further obtaining a confidence risk value of the current disease course stage of the target patient; and carrying out risk prompting on the target patient based on the confidence risk value. By adopting the scheme of the invention, real-time modeling can be carried out on the dynamic change of the course of disease of the patient under the background of massive health data.

Noninvasive glucometer based on Raman spectrum

Resumen de: CN120392088A

The invention provides a non-invasive glucometer based on a Raman spectrum, and relates to the field of measurement. The non-invasive glucometer based on the Raman spectrum comprises a light source module, a dichroscope, a lens module, an optical filter and a photoelectric spectrum measurement module. The light source module, the photoelectric spectrum measurement module and the lens module are arranged corresponding to the dichroscope. The optical filter is arranged on the light inlet side of the photoelectric spectrum measurement module so as to filter out excitation light with short wavelength. The small photoelectric spectrum measurement module is used for detecting blood glucose, so that the size can be greatly reduced, the structure is compact, the price is low, large-scale production is facilitated, and the device is even used for wearable equipment.

Insulin pen and use method thereof

Resumen de: CN120393184A

The insulin pen comprises a penholder, a refill frame, a refill body, an injection head and a pen cap, the injection head comprises a needle, an adsorption sleeve, a first spring and an adjusting ring, the refill frame is installed at the upper end of the penholder, the refill body is detachably installed in the refill frame, and the injection head is detachably installed at the top of the refill frame; the pen holder sleeves the refill frame and is in threaded connection with the refill frame, the adsorption sleeve, the adjusting ring and the first spring are mounted on the needle head, a front needle tube is arranged on the upper end face of the needle head, a rear needle tube communicated with the front needle tube is arranged on the lower end face of the needle head, the needle head is in elastic sliding connection with the adsorption sleeve through the first spring, and exhaust holes are formed in the side wall of the adsorption sleeve. The insulin injection device has the advantages that the injection depth is accurately controlled, the needle head is prevented from shifting or being pulled out too early, the user operation convenience and the injection comfort are improved, and the problem that a traditional insulin injection device is difficult to accurately control the injection depth and the needle head stability is solved.

Non-invasive portable multi-mode wearable sweat sensing device

Resumen de: CN120392091A

The invention provides a non-invasive portable multi-mode wearable sweat sensing device, and belongs to the technical field of wearable biosensing devices. The preparation method comprises the following steps: dissolving ZrCl4, a monoacid regulator and terephthalic acid in an organic solvent, and then carrying out hydrothermal reaction; after the hydrothermal reaction is finished, collecting white precipitates, treating the white precipitates in a mixed solution of hydrochloric acid and DMF (Dimethyl Formamide), and then centrifuging, washing and drying to obtain an MOF carrier; and adding the MOF carrier, GOx and HRP into a buffer solution, stirring, centrifuging, and washing to obtain the enzyme-coated metal organic framework material. A detection point is prepared from an enzyme-coated metal organic framework material, and the detection point, a skin adhesion layer, a paper-based micro-fluidic layer and a packaging layer jointly form a non-invasive portable multi-mode wearable sweat sensing device. The sensing device can be directly integrated with the skin surface, continuously quantifies sweat loss in real time, and provides quantitative data of glucose in sweat.

Hydrogel microneedle patch for noninvasive blood glucose detection as well as preparation method and application of hydrogel microneedle patch

Resumen de: CN120392086A

The invention discloses a hydrogel microneedle patch for noninvasive blood glucose detection as well as a preparation method and application of the hydrogel microneedle patch. According to the invention, the microneedle patch is prepared by a turnover technology and is noninvasively applied to the skin surface, so that simple and rapid extraction of interstitial fluid in vivo and a new method for real-time, rapid and quantitative detection of blood glucose in vivo are realized. The hydrogel microneedle patch contains two hydrogel components: one hydrogel component is hydrogel which can be cured and formed by ultraviolet light, and the other hydrogel component is hydrogel which can be cured and formed by ultraviolet light; and the other hydrogel is functional hydrogel with pH responsiveness, and glucose oxidase is added, so that the hydrogel can sensitively react to in-vivo glucose. The double-response hydrogel is jointly mixed and prepared into a microneedle patch form, the microneedle patch is endowed with noninvasive/minimally invasive property when applied to the skin surface, the microneedle patch is very suitable for extraction of interstitial fluid in vivo, and then real-time, rapid and accurate detection of the blood glucose level in vivo is achieved.

Diabetic foot biological pressure feedback adjusting device and pressure point identification method

Resumen de: CN120392072A

The invention discloses a diabetic foot biological pressure feedback adjusting device and a pressure point identification method.The pressure adjusting method comprises the following steps that a foot intelligent wearable device is worn on a foot, and base line pressure signals of all pressure measuring areas and actual plantar pressure signals are collected; according to a preset sensor calibration coefficient, the actual plantar pressure signals of all the pressure measurement areas are converted into area pressure values, and pressure intensity values of all the pressure measurement areas are obtained through calculation in combination with pre-obtained contact areas of all the pressure measurement areas; for a pressure measurement area corresponding to the diseased area of the diabetic high-risk foot, based on the pressure intensity value of the pressure measurement area, calculating the actual emission reduction gas amount required by the pressure measurement area for pressure reduction; the opening degree and deflation time of a deflation electromagnetic valve corresponding to the pressure measurement area are calculated on the basis of the actual emission reduction gas amount, and the foot intelligent wearable device conducts pressure reduction adjustment on the abnormal pressure measurement area on the basis of opening degree adjustment and deflation time.

Systems and methods for analyte monitoring

Resumen de: CN120417831A

Digital and graphical user interfaces for a multi-analyte monitoring system are provided. For example, various embodiments of methods, systems, and interfaces for alarm interfaces, alarm setup interfaces, alarm unavailable interfaces and features, and sensor result interfaces are disclosed herein. Disclosed herein are various embodiments of interfaces related to glucose and ketone sensing.

Personalized adoptive non-invasive blood glucose monitoring method, system, device and medium

Resumen de: CN120392085A

The invention discloses a personalized adoptive non-invasive blood glucose monitoring method, system and device and a medium, and the method comprises the steps: obtaining a blood glucose sample and a physiological parameter sample of a target individual, and calibrating a trained universal artificial intelligence prediction model according to the blood glucose sample and the physiological parameter sample of the target individual, a personalized artificial intelligence prediction model is obtained; the universality artificial intelligence prediction model is obtained by training according to a blood glucose sample and a physiological parameter sample of a group; acquiring physiological parameters of the target individual, and monitoring blood glucose of the target individual according to the physiological parameters of the target individual and the personalized artificial intelligence prediction model; the physiological parameters are obtained through non-creative measurement. The embodiment of the invention can noninvasively, accurately and continuously monitor the blood glucose of the target individual, and can be widely applied to the technical field of blood glucose detection.

Multi-wavelength noninvasive blood glucose system calibration method, storage medium and blood glucose meter

Resumen de: CN120392083A

The invention discloses a multi-wavelength noninvasive blood glucose system calibration method which comprises the following steps: step 1, continuously detecting and recording pulse wave signals by a user, and taking obtained pulse wave signal measurement values as a data set A; 2, during the period of continuously detecting the pulse wave signals, part of time nodes are selected for one-time invasive blood glucose measurement, blood glucose measurement values are obtained, all the blood glucose measurement values are calculated based on an interpolation prediction method, and the user selects the same-period blood glucose prediction values within the duration time range of the time nodes and serves as a data set B; and step 3, based on the data set A and the data set B, establishing an individualized noninvasive blood glucose detection model of the user. According to the invention, the pricking frequency is reduced by about 10 times, so that the physiological discomfort and psychological burden of a testee are greatly reduced; or compared with a method for acquiring a data set through a minimally invasive sensor, the method does not need additional application type sensor consumables, and the detection cost is greatly reduced. The invention provides a more convenient and economical solution for calibrating the noninvasive blood glucose monitoring device for a testee, and is a beneficial innovation in the technical field of noninvasive blood glucose detection.

Diabetes detection system based on multi-sensor pulse characteristics

Resumen de: CN120392032A

The invention discloses a diabetes detection system based on multi-sensor pulse characteristics, and relates to the field of medical signal processing, and the diabetes detection system comprises a pulse wave data acquisition module which uses a pressure sensor and a photoelectric sensor to collect wrist pressure pulse waves and fingertip photoelectric volume pulse waves of a user; the preprocessing module is used for obtaining usable single-cycle pulse wave data; the signal fusion module is used for converting the pressure pulse wave signal and the photoelectric volume pulse wave signal into two-dimensional image signals through continuous wavelet transformation so as to reserve time-frequency domain information, and processing two two-dimensional images by using non-subsampled shear wave transformation and a pulse coupling neural network; the feature extraction and calculation module is used for extracting pulse wave image features through a ResNet network and finally performing classification through a random forest; according to the detection system, the fusion effect is improved under the condition that the calculated amount is not increased, the effect of noninvasive detection of diabetes by using multiple sensors is achieved, and the detection accuracy is improved.

Insulin pump

Resumen de: CN223170088U

The utility model belongs to the field of medical auxiliary instruments, and particularly relates to an insulin pump. The insulin pump comprises an insulin pump body, a battery cover is installed at the position of a battery bin on the insulin pump body in a threaded mode, an installation groove is formed in the top of the battery cover, a push plate of an L-shaped structure is arranged in the installation groove, and one end of the push plate is hinged to the groove wall of the installation groove; the push plate can freely swing outwards, the swing end of the push plate is attached to the cover top of the battery cover, and a groove convenient for fingers to press is formed in the plate wall, facing the cover top, of the push plate after swinging; an anti-disengaging assembly used for preventing the push plate stored in the mounting groove in a swinging mode from disengaging is arranged on the mounting groove. The swing end of the push plate is attached to the top of the battery cover in a swing mode, fingers are pressed into the grooves in the push plate, the grooves are used for positioning the fingers, the push plate is pushed through the fingers, the push plate drives the battery cover to rotate, and therefore the battery cover is disassembled or assembled, the disassembling and assembling process is convenient and fast, and other auxiliary tools are not needed.

Multifunctional insulin pen

Resumen de: CN223170098U

The utility model relates to the technical field and discloses a multifunctional insulin pen. The multifunctional insulin pen comprises a driving tube, a pushing rod, a core sleeve, a needle head and a protective sleeve. A driving assembly is arranged in the driving pipe, and the driving pipe is movably connected with the pushing rod through the driving assembly; the pushing rod comprises an outer pushing pipe and an inner pushing rod; the inner push rod is movably connected with the outer push tube, the core sleeve is detachably connected with the outer push tube, one end of the inner push rod is located in the core sleeve, the other end of the core sleeve is detachably connected with the needle head, and the protective sleeve is detachably connected with the needle head. Guiding can be provided when a patient uses insulin, automatic injection can be achieved, and the injection time efficiency is fully guaranteed.

Sweetness perception threshold detection method and detection system based on dynamic gradient feedback

Resumen de: CN120392021A

The invention relates to a sweet perception threshold detection method and detection system based on dynamic gradient feedback, and belongs to the technical field of animal behavior detection. The method comprises the following steps: preparing a sucrose solution with gradient concentration; respectively collecting the time and the pressure when the animal contacts the bottle mouth; calculating the contact ratio of the animal to the sucrose solution under each concentration; constructing a mathematical model section by section to fit a relation curve between the contact ratio and the concentration of the sucrose solution; judging whether the perception of the animal on the sugar concentration is obviously changed according to the slope, and determining a sweetness perception threshold value; and inducing a sugar solution aversion reaction to verify whether a threshold result is reliable or not. According to the method, the Lw value-concentration curve slope is introduced to analyze the sensitivity of animals to sucrose solutions with different concentrations, physiological perception and random preference can be effectively distinguished, and the accuracy of sweet perception threshold detection is effectively improved; and the calculation of Lw integrates two parameter indexes of contact time and licking pressure, so that the accuracy of sweet taste sensing threshold detection is further improved.

MACHINE LEARNING BASED SYSTEM AND METHOD FOR IDENTIFYING PATIENTS AT RISK OF NON-ADHERENCE AND RELEVANT PATIENT INTERVENTION PLANS

Resumen de: WO2025159993A1

Disclosed herein is a healthcare management system and method utilizing machine learning based predictive analytics to improve patient adherence rates for chronic care management (e.g., diabetes). An example system may include a computing device configured to establish a customer analytical record to synthetize over a plurality of selected attributes to form a patient centric view of patient behaviors, attitude, characteristics based upon data related to chronic disease state management and social determinants of health, consumer experience to determine, using a predictive artificial intelligence model, a patient's predictive adherence for next 1-3 months, and determine tailored intervention plans to engage patients for continuing adherence.

GLUCOSE PROFILE IN NAILS

Resumen de: WO2025157775A1

The present invention relates to a method for obtaining at least one item of nail information on at least one nail (130) of a living being by at least one spectroscopic measurement, the method comprising: i. acquiring spectral information by using at least one spectrometer device (124) at one or more different measurement position; ii. acquiring at least one item of reference information on at least one reference position by using at least one reference position measurement unit (136); and iii. evaluating the spectral information for obtaining the at least one item of nail information on the at least one nail (130), wherein, by evaluating the at least one item of reference information on the at least one reference position when evaluating the spectral information, the measurement position for any item of nail information on the at least one nail (130) is obtained.

ANALYTE SENSOR SENSITIVITY ATTENUATION MITIGATION

Nº publicación: US2025241598A1 31/07/2025

Solicitante:

ABBOTT DIABETES CARE INC [US]
ABBOTT DIABETES CARE INC

Resumen de: US2025241598A1

Method and apparatus for receiving a first signal indicative of first glucose levels measured by a first working electrode, receiving a second signal indicative of second glucose levels measured by a second working electrode, detecting a first decrease in an amplitude of the first signal measured by the first working electrode that exceeds a first threshold, detecting a second decrease in an amplitude of the second signal measured by the second working electrode that exceeds the first threshold, selecting the first signal based on determining that the first decrease in the amplitude of the first signal is less than the second decrease in the amplitude of the second signal, determining a rate of change corresponding to the first decrease in the amplitude of the first signal, comparing the rate of change to a second threshold, confirming, based on the comparison, that the first signal is valid.