Resumen de: EP4772611A1
The present invention relates to a basal medium composition for animal cells. The basal medium composition for animal cells according to the present invention contains a yeast extract, amino acids, an inorganic salt, and a sugar, wherein the amino acids in the composition include cystine and/or cysteine, and glutamine.
Resumen de: EP4773258A1
A bioelectrode includes: a complex compound including a metal and a ligand; a mediator having an anionic functional group; and a conductive material.
Resumen de: US2025169728A1
The present disclosure describes lactate-responsive sensors, sensing systems incorporating a lactate-responsive sensor, and methods of use thereof that would be beneficial for continuously monitoring lactate levels and determining lactate thresholds (both aerobic and anaerobic thresholds). The present disclosure also relates to an analyte sensor for continuously detecting glucose and lactate levels.
Resumen de: GB2644972A
Growth-enhancing peptides and fusion polypeptide are provided. The peptides and fusion polypeptides may be used in cell culture, in particular in the production of cultured meat, as replacement or addition to insulin. There is further provided a cell culture medium comprising at least one of the peptides or fusion polypeptides, and a method for growing cells comprising adding at least one of the peptides or polypeptides to the cell culture medium.
Resumen de: CN224441828U
The utility model discloses an auxiliary extruder for fat emulsion amino acid glucose injection, which comprises a main roll shaft, a first press roll and a second press roll, the first press roll and the second press roll are parallel to the main roll shaft, the end of the first press roll is connected with the end of the main roll shaft through a first connecting rod, and the end of the second press roll is connected with the end of the main roll shaft through a second connecting rod. At least one end of the second connecting rod is in pivot connection with the second connecting rod or the main roller shaft, a clamping groove matched with the injection bag in thickness is formed in the main roller shaft, and the clamping groove extends in the axial direction to form a long-strip-shaped structure. The utility model provides an auxiliary squeezer for fat emulsion amino acid glucose injection, which can simulate the existing manual squeezing action, squeeze a bag from the edge position of the injection bag, facilitate the quick stripping of a seal between cavities, prevent fingers for operating medical care from being squeezed, and ensure the safety of medical care. And fingers for operating medical care can be protected.
Resumen de: CN122320469A
The invention discloses a special integrated nano-robot system for medical beauty, and belongs to the technical field of minimally invasive and non-invasive diagnosis and treatment for civil medical beauty. According to the system, glucose modified PCL with the glucose grafting rate of 20-25 wt% is used as a core base material, the particle size range of 100-200 nm (the median value is 150 nm) is adapted, the system is of a resolution-free integrated structure, the surface of a main body is coated with a gamma-polyglutamic acid modification layer, six functional units including skin precise detection, precise drug delivery, minimally invasive ablation, repair and regeneration, pore cleaning and safe regulation and control are embedded, and the system has the advantages that the system is simple in structure and convenient to operate, and the system is suitable for large-scale popularization and application. And each unit realizes signal intercommunication with the safety regulation and control unit through a carbon nano tube nano conduction link. The safety regulation and control unit and the gamma-polyglutamic acid modification layer are matched through specific logic to construct special pH dual-redundancy control logic for the medical beauty scene, the normal skin false triggering rate is smaller than or equal to 0.05%, the cytotoxicity and mucous membrane irritation are both in the level 0, and the degradation period is 14 +/-2 days. The preparation process of the system
Resumen de: CN224441842U
The utility model discloses a diabetes mellitus positioning syringe, which relates to the technical field of syringes and comprises a support, two parallel connectors are mounted on one side of the support, guide rings are mounted outside the connectors, clamping holes are formed in the guide rings, and the connectors are inserted into the clamping holes. Two guide rings are arranged on the support, connectors are fixedly arranged at the lower end of the support, fixing pieces are arranged between the connectors and the guide rings, an attaching plate is fixedly arranged at the lower end of the support, an indicating hole is formed in the attaching plate, the indicating hole and the two guide rings are coaxially arranged, an adjusting seat is fixedly connected to the end of one connector, and a sliding groove for the adjusting seat to slide up and down is formed in the support. According to the utility model, an injection point position can be confirmed in advance through the indication hole, the two guide rings can jointly guide and limit the injector, and during injection, the injector is inserted along the two guide rings, so that a needle head of the injector can penetrate through the indication hole to be accurately pricked on the preset point position.
Resumen de: US20260188443A1
0000 A method of providing personalized treatment for a diabetes patient including a remote device which is configured to receive a first data indicative of an analyte level of a subject during a first time period, retrieve a first glycated hemoglobin level for the subject associated with the first time period, calculate a first personal apparent glycation ratio for the first time period using the received first data and the retrieved first glycated hemoglobin level, compare the calculated first personal apparent glycation ratio to a representative apparent glycation ratio, generate a recommendation based on the comparison, and display a graphical interface comprising the calculated first personal apparent glycation ratio, the representative apparent glycation ratio, and the comparison.
Resumen de: US20260183397A1
0000 The present invention relates to a method for expansion of a population of lymphocytes in a controlled single culture vessel, the method comprising a step of (a) culturing a tissue or blood sample from a subject, which sample is known or suspected to contain lymphocytes; or (b) culturing lymphocytes, which lymphocytes are isolated from a tissue or blood sample from a subject; wherein the lymphocytes are expanded in a culture medium in which at least one of the following parameters is monitored and adjusted to a predefined value or range: pH, dissolved oxygen (DO) concentration, glucose concentration, lactate concentration and/or temperature; and wherein the method comprises a step of adjusting the culture volume to the expansion rate of the lymphocytes. Furthermore, the invention relates to a population of lymphocytes comprising at least 90% CD3+ T cells and less than 5% B cells, wherein at least 70% of said T cell portion are viable, optionally, and less than 10% are triple positive for CD45RA, CD57 and KLRG1.
Resumen de: US20260182870A1
0000 Techniques disclosed herein relate to food analysis and glucose level management. In some examples, the techniques involve determining a consumption of a food item by a user, receiving data indicative of a glucose level of the user, determining an effect of the food item on the glucose level of the user based on a change of the glucose level of the user, and storing the effect of the food item on the glucose level of the user that includes data associated with one or more effects of the food item on the glucose level of the user.
Resumen de: WO2026142802A1
Certain aspects of the present disclosure provide a therapy management system configured to monitor at least glucose concentration levels of a patient during a first time period using one or more glucose sensors to obtain glucose data, and determine a diabetic state classification of the patient based on the glucose data. The diabetic state classification indicates a diabetic state of the patient and comprises one of: a healthy classification, a pre-diabetic classification, a mild type 2 diabetes (T2D) classification, a severe T2D classification, or a gestational diabetes classification. The therapy management system is further configured to provide personalized feedback to the patient based on the determined diabetic state classification, wherein the personalized feedback comprises a recommendation for at least one of an exercise session, a dietary change, a lifestyle modification, a medication adjustment, or a continuous glucose monitoring wear schedule.
Resumen de: WO2026142937A1
In some embodiments, a method of automatically adjusting insulin therapy for a patient includes receiving, at a device associated with the patient, one or more glucose measurements generated by a continuous glucose monitoring (CGM) system of the patient for a period. The method also includes determining, at the device, basal insulin data and bolus insulin data of the patient for the period. The method also includes determining, at the device, a relationship between the basal insulin data and the bolus insulin data. The method also includes generating, at the device, an insulin therapy instruction for the patient based on the one or more glucose measurements and the determined relationship between the basal insulin data and the bolus insulin data, where the insulin therapy instruction includes a total bolus amount.
Resumen de: WO2026142537A1
Present invention relates to a needle-free glucose measurement system which enable measurement of blood glucose level using concentration value of N2O molecule available in breath air, which comprises an electronic assembly (1.1) which stabilizes the temperature and flow of wavelength-adjustable laser light source (1.2) and controls wavelength, a laser-based sensor (1) which determines concentration values of N2O molecule by measuring the adsorption amount of detector (1.5) wherein beams coming from laser light source (1.2) are adsorbed by N2O molecules in the breath air in the adsorption cell (1.4), and a processor (2) which determine glucose values in the blood using the concentration data coming from laser-based sensor (1).
Resumen de: WO2026142762A1
In an embodiment, a system for mitigating diabetic ketoacidosis (DKA) risk for a patient in real-time includes a continuous glucose monitoring (CGM) system configured to generate one or more glucose measurements associated with a cunent glucose level of a patient over a period, one or more memories including executable instructions, and one or more processors in data communication with the one or more memories. The one or more processors are configured to execute the executable instructions to receive glucose measurements for the patient from the CGM system, receive insulin data for the patient, evaluate criteria associated with DKA using first information related to the glucose measurements and second information related to the insulin data, detect a risk of DKA for the patient responsive to a combination of the first information and the second information satisfying the criteria associated with DKA, and alert the patient based on the detected risk.
Resumen de: US20260182933A1
In accordance with some implementations, a method includes obtaining blood glucose (BG) data indicative of BG levels of an individual. The method includes obtaining a first sleepiness score associated with the individual. The method includes determining, based at least in part on the BG data, that a low blood sugar alert condition is satisfied. The method includes, in response to determining that the low blood sugar alert condition is satisfied, directing an alert subsystem to generate a first alert output based on the first sleepiness score.
Resumen de: US20260183483A1
0000 A system for managing a patient's glucose level includes a glucose sensor to generate and store data signals for measurements of the patient's glucose level made by the glucose sensor; an insulin pump; and sensor electronics operatively coupled to the glucose sensor, the sensor electronics comprising a memory storing one or more predetermined characteristics associated with the sensor electronics; and a computing device in electronic communication with the sensor electronics. The computing device comprises a processor configured to operate the sensor electronics to (i) receive the generated data signals, (ii) obtain the one or more predetermined sensor characteristics from the memory and (iii) execute a closed-loop algorithm to provide insulin delivery instructions to an insulin pump by at least using the data signals and predetermined characteristics.
Resumen de: WO2026143067A1
The present disclosure provides compositions of stem cell-derived pancreatic islet cells engineered for improved engraftment and methods of use thereof for treating a subject having an insulin deficiency.
Resumen de: US20260182845A1
0000 A wearable device for measuring blood glucose and blood pressure for a user includes a main body including a first side and a second side formed on the opposite side of the first side; a first supporting frame protruding from the first side and a second supporting frame protruding from the second side; a belt portion having a first belt end detachably coupled to the first supporting frame, a second belt end detachably coupled to the second supporting frame, and at least one aligning mark, wherein the belt portion is positioned around a wrist of the user; wherein the main body includes at least one pressure sensor array assembly overlaid on a radial artery of the user; wherein the pressure sensor array assembly includes a plurality of apertures arranged one after another to form a cross-shaped pattern and at least four sensor elements arranged in a symmetrical configuration.
Resumen de: WO2026141270A1
Provided is an information processing system that provides users more useful information for improving blood sugar levels. The information processing system acquires meal information about meals consumed by a user, and outputs recommendation information on the basis of the meal information, user information, blood glucose level information, and behavioral information. Additionally, the information processing system outputs predicted blood glucose levels on the basis of meal information, user information, blood glucose level information, and behavioral information, the predicted blood glucose levels being for the case in which the user consumes a meal corresponding to the meal information. The information processing system also outputs blood glucose level prediction information on the basis of the recommended information. Moreover, the information processing system provides the user with blood glucose level prediction information based on meal information, recommendation information, and blood glucose level prediction information based on the recommendation information.
Resumen de: WO2026141211A1
The present invention accurately predicts and notifies the degree of daily discomfort after food intake. The present invention comprises: an acquisition unit that acquires blood glucose-related data related to the blood glucose level of a subject; a prediction unit that, on the basis of the blood glucose-related data, predicts the degree of daily discomfort after a prescribed amount of time from food intake by the subject; and an output unit that outputs the result of prediction by the prediction unit.
Resumen de: AU2024389410A1
A continuous analyte monitoring system includes first and second analyte sensors configured to sense analytes such as lactate and glucose in the tissue of a user. A controller Is coupled to the analyte sensors and configured evaluate first samples of outputs of the first analyte sensor and second samples of outputs of the second analyte sensor with respect to one another to determine whether the first samples and the second samples indicate compression of the tissue. If the first samples and the second samples indicate compression of the tissue, compensate for the compression of the tissue with respect to the first samples. The controller may evaluate the machine learning models using a machine learning model or a filter.
Resumen de: US20260182869A1
0000 A patient health management platform implements a machine-learned metabolic model to generate a prediction of a patient's glucose level. The platform implements a short-term prediction model to generate a daily prediction of the patient's glucose level based on nutrition data reported by the patient and sensor data and lab test data collected for the patient. The platform implements a long-term prediction model generate a prediction of the patient's glucose level during an extended time period based on sensor data and lab test data collected for the patient. Using the short-term prediction model, the long-term prediction model, or both, the patient health management platform generates predictions of the patient's glucose level and updates a digital twin of the patient's metabolic profile.
Resumen de: US20260184796A1
0000 Aspects of the present disclosure are directed to methods and compositions for facilitating β-cell regeneration by inhibition of the HIF1α-PFKFB3 pathway. Certain aspects describe methods for treatment and prevention of prediabetes and diabetes, including type 2 diabetes. Also disclosed are methods and compositions for enhancing β-cell regeneration.
Resumen de: US20260188503A1
A method of providing performance reports to persons associated with the monitoring of an analyte level, such as blood glucose concentrations in a host, is provided. The performance reports can indicate a measure of an analyte variability of the host over a first analysis time period compared to a measure of analyte variability of the host over one or more other analysis time periods. The analyte level of the host can be received in each of a plurality of sensor readings from a continuous analyte sensor, such as multiple sensor readings per hour, so that the analyte variability that is used in determining the performance report of the host can be based on not just a few metered readings taken by the host, but a plurality of intermittent readings that are taken by a continuous analyte sensor, for example. Various types of performance reports can be generated, such as reports that comprise charts, graphs, tables, and/or other visual indicia of a host's performance during one analysis period versus another analysis period.
Nº publicación: US20260182931A1 02/07/2026
Solicitante:
WILLOW LABORATORIES INC [US]
Willow Laboratories, Inc.
Resumen de: US20260182931A1
0000 The disease management system can determine a measurement of one or more physiological parameters and can determine a disease event based on the one or more measurements. Furthermore, the disease management system can determine a pose of an individual using a pose sensor. Based on an identification of a disease event and a determination that the pose of the individual corresponds to a first pose, the disease management system can cause at least one of an audible, visual, or vibratory alarm. Based on an identification of a disease event and a determination that the pose of the individual does not correspond to the first pose, the disease management system can cause administration of a medication to the individual.