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Insulin injection positioning and guiding equipment and method thereof

Resumen de: CN121371392A

The invention discloses an insulin injection positioning and guiding device and a method thereof.The insulin injection positioning and guiding device comprises a multi-mode sensing module, a central processing module and a guiding execution module, and the multi-mode sensing module is used for obtaining various physiological information of an injection area; the central processing module is in signal connection with the multi-mode sensing module and used for fusing various kinds of physiological information to determine an optimal injection site and calculating and recommending an injection angle according to subcutaneous tissue information of the optimal injection site and the length of a needle head, and the guiding execution module is in signal connection with the central processing module and used for guiding the injection angle to be recommended according to the subcutaneous tissue information of the optimal injection site and the length of the needle head. And the multi-modal sensing module is used for executing injection guidance or operation according to the determined optimal injection site and comprises a visual imaging unit, a multispectral imaging unit and a biological impedance measuring unit. According to the insulin injection positioning and guiding equipment, intelligent positioning and guiding of insulin injection are achieved, and the accuracy and safety of insulin injection are improved.

Noninvasive blood glucose detection device based on multi-signal feature fusion

Resumen de: CN121370160A

The invention discloses a noninvasive blood glucose detection device based on multi-signal feature fusion, which comprises a host and an acquisition probe, and multiple signals comprise a photoacoustic signal and a photoelectric plethysmography (PPG) signal. By performing quality evaluation on the collected PPG signal, the optimal action position of the incident laser on the human body is positioned, so that the laser energy is concentrated in a blood vessel area, and the stability and repeatability of photoacoustic detection are improved. Meanwhile, feature extraction and fusion are performed on the photoacoustic signals and the PPG signals, and a blood glucose prediction regression model is established by utilizing a machine learning algorithm, so that the precision and reliability of noninvasive blood glucose detection are improved.

Insulin pump data migration method and system, electronic equipment and storage medium

Resumen de: CN121389103A

The embodiment of the invention provides an insulin pump data migration method and system, electronic equipment and a storage medium, and belongs to the technical field of communication. The method is applied to an original insulin pump and comprises the following steps: acquiring magnetic field characteristic information of a target insulin pump, and performing magnetic field characteristic verification on the magnetic field characteristic information to obtain magnetic field verification result information; in response to the condition that the magnetic field verification result information meets a preset magnetic field verification passing condition, performing cascade encryption on a target equipment identifier and a check code sent by the target insulin pump according to the first key character to obtain an encrypted string body; performing data integrity verification on the encrypted string body to obtain data verification result information; in response to the condition that the data verification result information meets the preset integrity verification passing condition, migrating the user data to the target insulin pump. According to the embodiment of the invention, the safety verification reliability of the insulin pump can be improved, and then the user data of the old insulin pump can be safely migrated to the legal new pancreas islet pump.

Diabetic foot treatment system and control method

Resumen de: CN121371499A

The invention discloses a diabetic foot treatment system and a control method, and relates to the technical field of diabetic foot treatment.The diabetic foot treatment system comprises a multi-point temperature measuring unit, a laser positioning unit, a photographing recognition unit, an intelligent verification unit and a power adjusting unit; multi-source data such as training set image similarity, foot standard temperature and motor nerve conduction velocity are comprehensively analyzed through the intelligent verification unit, and the preliminary level is verified in combination with a preset confidence index formula, so that model prediction deviation caused by training data labeling errors or insufficient sample size can be effectively identified and corrected; through a preset direct adjustment rule, adjacent grade confidence index comparison and introduction of a medical expert determination mechanism, the accuracy of diabetic foot grade judgment is effectively improved; and secondly, the power adjusting unit dynamically calculates the output power of the radio frequency treatment equipment based on the finally determined diabetic foot grade and the real-time temperature data, so that accurate regulation and control of treatment parameters are realized.

Blood glucose protection microsphere, preparation method thereof and application of blood glucose protection microsphere in vacuum blood collection tube

Resumen de: CN121371331A

The invention discloses a blood glucose protection microsphere, a preparation method thereof and application of the blood glucose protection microsphere in a vacuum blood collection tube, and belongs to the technical field of medical instruments. The blood glucose protection microsphere is prepared by the following steps: preparing a solution from an anticoagulant, an anti-glycolysis agent, an excipient and a protective agent in proportion, freezing the solution through liquid nitrogen drop beads to form a microsphere precursor, and performing vacuum freeze drying to prepare a freeze-dried microsphere with the diameter of 2.0-6.0 mm. According to the preparation method, various functional reagents are integrated into the microspheres at one time, the process is simple, and energy conservation and consumption reduction are achieved. The microspheres can be quickly dissolved and uniformly dispersed when being applied to the vacuum blood collection tube, glycolysis is effectively inhibited, hemolysis is prevented, the accuracy and reliability of blood glucose detection are improved, and meanwhile, product quality control is facilitated.

Method for detecting pancreas in combination with sample mining and migration neural network

Resumen de: CN121392826A

The invention discloses a method for detecting pancreas in combination with sample mining and a migration neural network. The method comprises the following steps: acquiring a magnetic resonance image of a to-be-measured target; and inputting the magnetic resonance image into a trained classification model to obtain a classification result of pancreatitis. The classification model comprises a region generation module and a detection module, the detection module comprises a migration bottleneck layer, a top layer and a classification layer, and the region generation module takes a magnetic resonance image array as input and outputs a magnetic resonance image array with candidate regions; the migration bottleneck layer extracts bottleneck features of each slice for the magnetic resonance image array with the candidate area, and then inputs the bottleneck features to the top layer to obtain top layer features, and the classification layer obtains a classification result of pancreatitis based on the top layer features. The method is high in prediction accuracy, and can effectively predict pancreatitis and assist artificial diagnosis.

System and method for intelligently monitoring blood glucose of patient before and after diet based on food ingredients

Resumen de: CN121393931A

The invention discloses a system and a method for intelligently monitoring blood sugar of a patient before and after diet based on food components, and belongs to the technical field of blood sugar monitoring, and the system comprises a food component quantification module which is used for converting a food image or description into accurate macro nutrient and micronutrient data; the multi-modal data fusion module is used for preprocessing and fusing the multi-modal data of the patient; the patient blood sugar prediction module is used for constructing a patient blood sugar prediction model to analyze the multi-modal fusion data of the patient and predicting the blood sugar of the patient; and the difference analysis optimization module is used for comparing actual blood glucose with predicted blood glucose after meal and analyzing difference reasons. The problems that blood glucose of a patient before and after eating cannot be intelligently monitored, and accurate quantification and prediction of the relation between diet and blood glucose cannot be achieved are solved. The system can intelligently monitor the blood glucose of the patient before and after eating, can help the diabetic to realize accurate quantification and prediction of the relationship between diet and blood glucose, and can effectively control the blood glucose and reduce the risk of complications.

Portable multi-parameter integrated community diabetic foot early screening device

Resumen de: CN121370069A

The invention relates to the technical field of diabetic foot early-stage screening, and discloses a portable multi-parameter integrated community diabetic foot early-stage screening device which comprises a first box body, a hinge is fixedly connected to the right side of the first box body, and the first box body is rotationally connected with a second box body through the hinge; supporting blocks are evenly and fixedly connected to the sides, away from each other, of the first box body and the second box body, a detection pad is fixedly connected to the inner wall of the first box body, through holes are evenly formed in the detection pad, detection needles are slidably connected to the interiors of the through holes, and a mounting plate is fixedly connected to the lower portions of the detection needles; and the lower part of the mounting plate is fixedly connected with a connecting frame. According to the diabetic foot early-stage screening device, through cooperation of a micro motor, a gear, a rack plate, a connecting column, a connecting frame, a mounting plate, a sliding block, a detection needle and other structures, the diabetic foot early-stage screening device can sequentially screen the two feet of a patient, the patient can clearly sense the foot positions where pressure and pain are transmitted, meanwhile, feet do not need to be exchanged, and convenience is improved.

Insulin injection positioning device

Resumen de: CN223817969U

An insulin injection positioning device comprises a positioning plate, the positioning plate is provided with a remark area and an injection calibration area located above the remark area, the injection calibration area is composed of seven finger-shaped strips arranged side by side, and each finger-shaped strip is provided with three injection limiting holes. The heights of the seven side-by-side finger-shaped strips are gradually decreased towards the two sides with the middle finger-shaped strip as the center. A patient can be assisted in insulin injection through the injection limiting hole in the injection calibration area, the recent insulin injection position can be accurately known through character prompts on the remark area, and repeated injection on the same part of the patient within a short time is avoided due to the fact that the patient is guided to inject at different points.

Insulin injection position prompting disc

Resumen de: CN223817968U

The utility model discloses an insulin injection position prompting disc, and mainly relates to insulin injection. Comprising a disc body, an umbilical hole is formed in the surface of the disc body, a plurality of indication holes are formed in the surface of the disc body, an adjusting structure is arranged on the surface of the disc body, the adjusting structure comprises a fixing frame, the fixing frame is fixedly connected with the disc body, the arc surface of the fixing frame is rotatably connected with a bandage, the surface of the bandage is slidably connected with a fixing plate, and the fixing plate is fixedly connected with the disc body. A hook-and-loop fastener and a hook-and-loop fastener are arranged on the surface of the bandage, an adjusting frame is fixedly connected to one side of the fixing plate, and an adjusting rod is rotationally connected to the inner wall of the adjusting frame. The lumbar disc has the advantages that the disc body can be fixed to the waist of a patient, the patient can conveniently conduct injection operation, the bandage is operated to roughly adjust the tightness degree, the disc body is worn through the clamping plate and the clamping frame in the follow-up wearing process, operation is easy and convenient, the tightness degree is finely adjusted through the handle, and operation convenience is provided for the patient.

Stable and durable wearable sweat and sugar electrochemical sensor

Resumen de: CN121370157A

The invention provides a stable and durable wearable sweat and sugar electrochemical sensor. A sensing interface of the sensor is prepared by sequentially dispensing a glucose sensing solution and a film forming solution on the surface of a carbon electrode, the glucose sensing solution comprises a zeolite imidazate framework-90 (ZIF-90 at GOx) composite material loaded with glucose oxidase, Prussian blue nanoparticles (PBNPs) and a conductive gel solution, and the film forming solution comprises ammonium persulfate and tetramethylethylenediamine. Glucose in sweat is oxidized by using ZIF-90 at GOx on a sensing interface, generated hydrogen peroxide reacts with PBNPs to generate a current signal on an electrode, and then quantitative analysis is performed on the glucose in the sweat based on a standard curve method. The wearable sweat and sugar electrochemical sensor provided by the invention has excellent environmental adaptability and durability, can be used outdoors for a long time, is simple to prepare and good in product performance, and has a very good application prospect in the field of development of wearable sweat and sugar sensors.

IMPROVING AN ACCURACY OF GLUCOSE PREDICTIONS FOR PATIENTS BY FACILITATING SUBMISSION OF CONTEXTUAL DATA

Resumen de: WO2026019913A1

In an embodiment, a method includes receiving analyte measurements of a patient for a time period. The method further includes providing, to a user, an interface for supplying contextual data indicative of contextual events for the time period and receiving the contextual data via the provided interface. The method further includes analyzing the analyte measurements and the contextual events to determine a condensed timeline of patient data for the time period, the condensed timeline of patient data including a partial subset of the contextual events. The method further includes presenting information related to the condensed timeline to the patient.

METHOD TO AVOID HYPOGLYCEMIA BY MINIMIZING LATE POST-PRANDIAL INSULIN INFUSION IN AID SYSTEM

Resumen de: WO2025064417A1

Embodiments can relate to an insulin delivery controller which implements a processor configuration to efficiently attain an insulin delivery target. The insulin delivery controller can include a processor and a memory associated with the processor. The processor can process glucose data received from the memory, including a data representation of glycemic disturbance (d(t)). The processor can determine a glucose rate of change (G'(t)). The processor can generate a command signal to dynamically reshape a glycemic disturbance within a prediction horizon of the insulin delivery controller according to the G'(t). The processor can generate an insulin command signal for an insulin delivery unit to adjust an insulin delivery dosage amount and/or an insulin delivery dosage rate.

DECISION SUPPORT FOR GLUCOSE-KETONE SENSOR

Resumen de: AU2024343861A1

A system includes an analyte measurement system and a software application operatively coupled to the analyte measurement system. The analyte measurement system is configured to measure a ketone level in the bodily fluid of a patient. The application is configured to display at least one of (1) a current ketone level and an indicator of a current ketone trend, (2) a ketone trend graph, and (3) a total amount of time that the ketone levels are above at least one predetermined threshold level. The application is also configured to determine if the current ketone level is above the at least one predetermined threshold level, and in response to determining that the current ketone level is above the at least one predetermined threshold level, output an alarm, wherein the alarm is outputted periodically while the current ketone level is above the at least one predetermined threshold level.

SENSOR FOR DETECTING GLUCOSE AND LACTATE AND METHODS FOR DETERMINING AEROBIC AND ANAEROBIC THRESHOLDS

Resumen de: AU2024335431A1

The present disclosure describes lactate-responsive sensors, sensing systems incorporating a lactate-responsive sensor, and methods of use thereof that would be beneficial for continuously monitoring lactate levels and determining lactate thresholds (both aerobic and anaerobic thresholds). The present disclosure also relates to an analyte sensor for continuously detecting glucose and lactate levels.

BLOOD GLUCOSE MEASUREMENT BASED ON RAMAN SPECTROSCOPY

Resumen de: AU2024280120A1

Blood glucose level measurement includes a light source configured to irradiate light to a subject; a monochrome part configured to separate wavelength components of the light that is reflected and scattered from the subject; a light receiver configured to receive the light transmitted via the monochrome part and to generate electrical signals based on the received light; and a processor configured to extract information on the blood glucose level of the subject based on a frequency shift of the light due to the Raman effect.

Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) Antibodies

Resumen de: US20260022182A1

The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.

MEDICINE INJECTION AND DISEASE MANAGEMENT SYSTEMS, DEVICES AND METHODS

Resumen de: US20260021256A1

One or more embodiments of the present disclosure may include an insulin delivery system that includes an insulin delivery device, a user interface that includes multiple user-selectable icons or buttons each representing different meal characteristics, memory to store one or more user-specific dosage parameter, and a processor in communication with the memory and adapted to receive blood glucose data. The processor may also be adapted to determine initial meal characteristics associated with each of the user-selectable icons or buttons based on at least one of the user-specific dosage parameters. The processor may also be adapted to update the meal characteristics associated with each of the user-selectable icons or buttons based upon the blood glucose data.

LOCAL ANESTHETIC SOLUTION FOR DENTAL AND/OR CONTRAST MEDIA USE

Resumen de: US20260021185A1

An improved local anesthetic solution with diminished bitter taste includes an anesthetic agent, an anesthetic solution vehicle, and a bitterness suppressant. The bitterness suppressant includes one or more compounds selected from the group consisting of: a sugar selected from the group consisting of monosaccharide sugars, disaccharide sugars, polysaccharide sugars, and combinations of the any of the foregoing; sweet-tasting compounds; acids; amino acids; salts; miscellaneous suppressant substances; and combinations of any of the foregoing. The improved local anesthetic solution optionally includes one or more additional agents selected from the group consisting of: buffering agents; vasoconstrictors; preservative compounds; stabilizers; contrast media agents; and combinations of any of the foregoing.

Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) Antibodies

Resumen de: US20260022183A1

The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.

MONITORING METABOLIC RESPONSE

Resumen de: US20260020784A1

Simulating a user's metabolic system and predicting a blood glucose response based on a specified food intake event includes receiving characteristic data representative of specified user characteristics, converting said characteristic data into object data and utilising said object data and a master model to generate a personal digital model representative of said user's metabolic system, receiving food intake data representative of a said specified food intake event, obtaining or generating current glucose data for said user, inputting said food intake data to said personal digital model, and generating, using said personal digital model, a simulation of said user's metabolic system in response to said food intake data and generating a predicted blood glucose response to said specified food intake event, outputting data representative of said predicted blood glucose response, and utilising said data representative of said predicted blood glucose response to retrain said master model and said personal digital model.

METHOD FOR MANUFACTURING INSERTION GUIDE NEEDLE FOR CONTINUOUS BLOOD GLUCOSE MONITORING DEVICE

Resumen de: US20260020779A1

The present disclosure relates to a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device. The present disclosure provides a method for manufacturing an insertion guide needle for a continuous blood glucose monitoring device, by which: an insertion guide needle can be manufactured through a cutting process and a bending process of a needle raw plate, so that a complicated manufacturing process is unnecessary, and can thus be easily manufactured through a simple process; an enlargement incision part for continuous enlargement and incision, etc. can be conveniently manufactured through such a simple processing process, so that a manufacturing cost thereof can be reduced and also the size accuracy of the insertion guide needle can be improved; and, particularly, in a process of inserting the insertion guide needle into skin, the insertion guide needle can be brought into point contact with the skin to cut the skin, and then can continuously cut the skin in an enlarged manner, so as to minimize pains which may occur in the process of inserting the insertion guide needle into the skin, thereby alleviating the sense of repulsion or tension at the time of using the continuous blood glucose monitoring device.

RAPID DETECTION OF HYPOGLYCEMIA INCIDENCE USING CONTINUOUS GLUCOSE MONITORING

Resumen de: US20260020780A1

Certain aspects of the present disclosure provide systems and techniques for rapid detection of repetitive metabolic events in a host based on measured analyte data provided by an analyte monitor worn by the host. An example system is configured to obtain measured glucose data of the host. A subset of the measured glucose data is determined, based on performing a filtering operation on the measured glucose data. A respective range of a likelihood of an occurrence of a metabolic is determined for each value within the subset of the measured glucose data. For at least one value within the subset of the measured glucose data, a state of the metabolic event is determined based in part on at least one of an upper bound or a lower bound of the respective range corresponding to the at least one value within the subset of the measured glucose data.

MAGNET SYSTEM FOR NUCLEAR MAGNETIC RESONANCE

Resumen de: US20260023141A1

The system can include: an array of magnets. In variants, the system can function to generate a homogenous magnetic field within a sample (e.g., in the pulp of a finger). In an example, the system can be used for nuclear magnetic resonance (NMR) imaging and/or magnetic resonance imaging (MRI). In a specific example, the system can be used to measure blood analyte levels (e.g., glucose levels) within a sample.

BODY ATTACHABLE UNIT FOR CONTINUOUS BLOOD GLUCOSE MEASUREMENT

Nº publicación: US20260020785A1 22/01/2026

Solicitante:

I SENS INC [KR]
I-SENS, INC

Resumen de: US20260020785A1

The present disclosure relates to a continuous blood glucose measurement body attachment unit, and provides a continuous blood glucose measurement body attachment unit, which is manufactured in an assembled state in an applicator so as to minimize separate additional operations, such that the body attachment unit can be attached to the body with only a simple operation of the applicator and, particularly, the body attachment unit has a wireless communication chip so as to be capable of communicating with an external terminal, thereby enabling simple and convenient usage without an additional operation in which a separate transmitter must be connected and enabling maintenance to be more easily performed, and after the body attachment unit is attached to the body, an operation starts by the control of a user, such that an operation start time point can be adjusted to an appropriate time point according to the needs of the user, and an operation can start in a stabilized state, such that blood glucose can be more accurately measured.