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APPARATUS AND METHODS FOR 3D PRINTING INTRAOCULAR LENS COMPONENTS, INTRAOCULAR LENS FORMULATIONS SUITABLE FOR 3D PRINTING, AND 3D-PRINTED INTRAOCULAR LENS COMPONENTS

Resumen de: US20260096877A1

Disclosed are apparatus and methods for 3D printing intraocular lens components, intraocular lens formulations suitable for 3D printing, and 3D-printed intraocular lens components. In one aspect, the intraocular lens formulation can comprise a plurality of monomers, a crosslinkable polymer comprising the plurality of monomers, a crosslinker, and a photoinitiator. Also disclosed is a 3D printer for printing an intraocular lens component. The 3D printer can comprise a reservoir configured to contain an intraocular lens formulation, a build platform comprising a build surface configured to be initially in fluid contact with the intraocular lens formulation within the reservoir, a light source configured to generate a light, and at least one of a mirror and a projection optic configured to direct the light generated by the light source at the intraocular lens formulation within the reservoir to cure and form one layer of the intraocular lens component on the build surface.

SACROILIAC JOINT FIXATION AND FUSION IMPLANTS

Resumen de: US20260096836A1

0000 Bone implants, assemblies, and methods thereof. The implants may include a tulip head and a bone fastener including a screw shank with bone threads, a distal tip configured to facilitate insertion into bone, and a proximal end having a screw head receivable in the tulip head. The screw shank may define one or more longitudinal windows and/or helical cuts filled with a lattice structure that acts as a scaffold for bone healing and bone interdigitation. The bone fastener, or a portion thereof, may be 3D printed, for example, using an additive laser powder bed fusion process to provide the integrated lattice structure.

THREE-DIMENSIONAL PRINTED DISPOSABLE PATELLA CLAMP

Resumen de: US20260096823A1

Disclosed herein is a disposable patella clamp. In some examples, the patella clamp is configured as a patient specific patella clamp that is custom designed to fit the anatomy of a particular patient. A patient undergoes diagnostic imaging which provides patient specific data including patella diameter and thickness, patella shape, and limb alignment. The imaging can be used to generate a 3D digital model of the patient's anatomy associated with the patellar region. The patella clamp can be designed and manufactured based on the model as an integrated clamp using an additive manufacturing process with biocompatible materials. The patella clamp may include one or more tracking elements operative to enable the patella clamp to be used with a computer-assisted and/or robotic surgical system.

SYSTEM AND METHOD FOR TRANSESOPHAGEAL ECHOCARDIOGRAM-GUIDED IMPLANTATION OF A VALVE DEVICE

Resumen de: US20260096880A1

0000 A system for transesophageal echocardiogram-guided implantation of a valve device, the system including at least a transesophageal echocardiogram system configured to detect at least an ultrasound image and at least a computing device configured to receive at least an ultrasound image, generate at least a 3D cardiac model representative of a heart of the patient as a function of at least an ultrasound image wherein the at least an ultrasound image includes a two-dimensional image of the heart of the patient and wherein the 3D cardiac model includes a three dimensional interpolation of the two-dimensional image, determine a valve model datum as a function of the 3D cardiac model, receive at least valve model representative of at least a cardiovascular device to be placed within the patient as a function of the valve model datum and display the at least a 3D cardiac model and at least a valve model.

SYSTEM FOR SHAPING AND IMPLANTING BIOLOGIC INTRAOCULAR STENT FOR INCREASED AQUEOUS OUTFLOW AND LOWERING OF INTRAOCULAR PRESSURE

Resumen de: EP4721936A2

0001 A system for deploying an implant cut from a biological tissue into an eye of a patient including a delivery device and a nose cone assembly, a tubular shaft projecting from the distal end region of the nose cone and comprising a lumen. Related devices, systems, and methods are provided.

SYSTEM FOR PAIRING A MEDICAL SYSTEM TO A NETWORK CONTROLLER BY USE OF A DONGLE

Resumen de: EP4723128A2

0001 The invention relates to a method comprising detecting, at a medical network interface, a pairing request received directly over a wireless connection from a standalone medical device, in response to the pairing request, authenticating the standalone medical device using a permission key, upon successful authentication, supplying one or both of a visual or audible indication that the pairing has been successful, wirelessly receiving a data stream from the standalone medical device, the data stream comprising patient data associated with a patient, associating with the data stream, an identifier of the patient and an identifier of the medical network interface, to produce a modified data stream, and transmitting the modified data stream across a hospital network to a server so as to enable distribution of the modified data stream to a plurality of devices from the server characterized in that the pairing request is received directly from the standalone medical device over a wireless connection, without use of a wireless dongle, and the medical network interface replies with pairing protocols or permission keys to establish the connection.

SYSTEMS AND METHODS FOR DICTATION WITH A DIGITAL STETHOSCOPE

Resumen de: EP4721670A1

The present description relates to methods and systems for a medical dictation. In one example, a stethoscope includes a first microphone positioned to capture physiological sounds of a patient, a second microphone positioned to capture ambient sounds, one or more processors, and memory storing instructions executable by the one or more processors to: during a stethoscope mode, obtain a first signal from the first microphone and a second signal from the second microphone, process the first signal to capture a physiological sound signal, including performing noise cancellation on the first signal based on the second signal, and transmit the physiological sound signal to an external computing device and/or a speaker of the stethoscope; and during a dictation mode, obtain the second signal from the second microphone, process the second signal to capture a voice signal, and transmit the voice signal to the external computing device.

PHOTOCURABLE COMPOSITION, THREE-DIMENSIONAL SHAPED OBJECT, CASTING MOLD, METHOD FOR PRODUCING CURED OBJECT, AND METHOD FOR PRODUCING DENTAL PROSTHESIS

Resumen de: EP4722262A1

0001 A photocurable composition includes: a (meth)acrylic monomer (A) having one or more (meth)acryloyl groups and not having a siloxane bond; a (meth)acrylic monomer (B) having two or more (meth)acryloyl groups and a siloxane bond; a compound (C) not having a (meth)acryloyl group and having a solubility parameter (SP value) of from 7.00 to 15.00 (cal/cm<3>)<1/2>; and a photopolymerization initiator.

CURABLE COMPOSITION COMPRISING AN ALKOXYLATED ISOSORBIDE DI(METH)ACRYLATE

Resumen de: EP4721721A1

The present invention relates to a curable composition comprising: a) at least one alkoxylated isosorbide di(meth)acrylate, b) at least one (meth)acrylate-functionalized oligomer, and c) at least one (meth)acrylate-functionalized monomer. The invention also relates to a process for the preparation of a cured product, especially a dental material, comprising curing this curable composition, preferably by exposing the curable composition to radiation such as UV, near-UV, visible, infrared, near-infrared and/or electron beam radiation.

NECK COLLAR AND METHOD OF MANUFACTURE

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

METHOD AND DEVICE FOR DESIGNING IMPLANT SURGICAL GUIDE FOR BONE REDUCTION

Resumen de: EP4721688A1

0001 Disclosed are a method and a device for designing an implant surgical guide for bone reduction. The method and the device for designing an implant surgical guide for bone reduction, according to an embodiment, can quickly and accurately perform bone reduction by designing a virtual bone reduction guide shape including a guide rail, when bone reduction is required for dental implant surgery.

METHODS AND SYSTEMS FOR CHANNEL IDENTIFICATION USING MANIFOLDS OF AN EAR-ELECTROENCEPHALOGRAPHY (EAR-EEG) SIGNAL

Resumen de: EP4721665A1

0001 Brain monitoring is performed using an Ear-electroencephalography (Ear-EEG) which records synchronized electrical behaviour of neurons in brain at high temporal resolution using a wearable ear device. For proper functioning of the wearable ear device, sensor electrodes need to be within the ear to remain in constant contact with the skin. However, body movements tend to disrupt extent of contact, leading to noisy signals being captured, which are often difficult to distinguish from a valid EEG signal. Thus, identification of channels that are capturing EEG is necessary. The present disclosure provides a method and system for channel identification using manifolds of an Ear-EEG signal. In the present disclosure, a plurality of manifold features are extracted from a signal received from the wearable ear device. The plurality of manifold features are further classified as EEG and non-EEG channels using an unsupervised clustering model across real-world stimuli in the wearable ear device.

OPEN LOOP INTELLIGENT DOSING

Resumen de: EP4723123A1

Systems, devices, and techniques are disclosed for providing personalized insulin dosage recommendations for a patient. In some aspects, a method includes generating a physiological model for estimating glucose values of the patient based on historical data, the historical data comprising glucose value history and insulin dosage history for a time window during which the patient consumed a plurality of meals. The method also may include estimating, using the physiological model and the historical data, an impact of the plurality of meals on the glucose values of the patient, and receiving a first meal size indication of a first meal for consumption by the patient. The method may also include outputting a first meal bolus insulin dose recommendation based on the impact of the plurality of meals on the glucose values of the patient and the first meal size indication.

STEREOLITHOGRAPHIC RESIN COMPOSITION

Resumen de: EP4722266A1

0001 The present invention provides a stereolithographic resin composition that exhibits excellent strength, toughness, water resistance, and impact resistance in the shaped article. The present invention relates to a stereolithographic resin composition comprising a polyfunctional (meth)acrylic polymerizable compound (A) with a molecular weight of less than 1,000, a polyfunctional (meth)acrylic polymerizable compound (B) with a molecular weight of 1,000 or more, a monofunctional (meth)acrylic polymerizable compound (C) that does not comprise a hydroxyl group and comprises a cyclic ether structure, and a photopolymerization initiator (D).

末梢神経を刺激するシステム及び方法

Resumen de: WO2024088537A1

Obstructive sleep apnea from blockage of the upper airway can result in significant daytime drowsiness, with many long-term co-morbidities associated with this disorder such as such as hypertension. A common cause of obstructive sleep apnea is the complete concentric collapse of the soft pallet or retrusion of the genioglossus muscle into the upper airway obstructing breathing. The latter can be due to exhaustion of the muscle due to heightened activation during wake periods, or a greater number of type II muscle fibers can contribute to muscle fatigue. It could also be neurological, whereby the hypoglossal nerve which controls most the upper airway muscles fails to innervate the genioglossus sufficiently to prevent backward movement and pharyngeal block. Described herein is an intelligent personalized closed loop neuromodulation system and methods to prevent backwards movement of the genioglossus muscle through stimulation of certain branches of the hypoglossal nerve and muscle motor points, by using muscle feedback from electromyogram sensors to provide optimal stimulus. Alternative embodiments to treat neuropathic pain and urinary dysfunction are enclosed.

採血キットおよび採血支援方法

Resumen de: JP2026059347A

【課題】患者が自身で採血を実施する場合に十分な量の血液の速やかな採取を支援するための技術を提供すること。【解決手段】患者１０によって実施される採血のための採血キットが提供される。採血キットは、添付書類３１を含む。添付書類３１は、採血を支援するための記述を含む。採血を支援するための記述は、穿刺が実施される手のマッサージ、穿刺が実施される手の圧迫動作、穿刺動作、穿刺箇所における血液の絞り出し、および、血液の採取を促す情報を含む。【選択図】図１

双颌数字化咬合板的制作与测试方法、系统、设备及介质

Resumen de: CN121796107A

本发明公开了一种双颌数字化咬合板的制作与测试方法、系统、设备及介质。对患者进行术前咀嚼肌去极化预处理，并获取其颞下颌关节软硬组织三维数据、面部比例数据、牙列形态数据及下颌动态运动轨迹数据；将软硬组织数据输入医学影像处理软件，结合牙列覆合覆盖情况，对髁突位置进行修正并虚拟定位至关节窝的中心位或肌骨稳定位，获得修正后数据；以修正后髁突位为颌位基准、面部比例为高度约束、动态轨迹为运动模拟依据，协同处理生成咬合板三维模型；根据模型制造实体，并对佩戴者进行肌电与咬合压力测试，并判断适配性，若异常则反馈调整模型并重新制造测试。本发明提升了咬合板的个性化适配精度、功能性与治疗可靠性。

一种个性化适配心肌软组织力学性能的仿生心肌电子补片及其制备方法

Resumen de: CN121796089A

本发明提供了一种个性化适配心肌软组织力学性能的仿生心肌电子补片及其制备方法，涉及再生医学领域。本发明提供的个性化适配心肌软组织力学性能的仿生心肌电子补片，包括可伸缩柔性纤维电极、沉积在所述可伸缩柔性纤维电极表面的组织工程纤维支架，所述纤维电极表面镀金纳米层和PDMS钝化层。本发明提供的仿生心肌电子补片复合接种人多能干细胞分化的心肌细胞的水凝胶后，实现无损监测及传递电刺激，同时组织工程纤维支架力学可调适配心肌组织力学性能。本发明提供的仿生心肌电子补片一体化集成柔性电极和纤维支架能够同时满足监测、刺激和适配心肌的生物力学性能。

支链含氟聚氨酯丙烯酸酯的制备方法及在3D打印光敏树脂组合物中的应用

Resumen de: CN121801048A

本发明公开了支链含氟聚氨酯丙烯酸酯的制备方法及在3D打印光敏树脂组合物中的应用，所述支链含氟型聚氨酯丙烯酸酯的主链富含苯环，不含氟，确保强度、耐温、耐压性能；其在支链上含有氟元素，在耐温、耐压性能的基础上提升耐水性能。其作为一种两官能度聚氨酯丙烯酸酯，确保光固化反应活性适中，又不易产生翘曲收缩，能够用于齿科3D打印光固化组合物有效解决精度、耐温性、耐水性及强度等诸多性能问题，具备显著的应用前景。

一种光固化复合树脂的仿生牙釉质梯度结构3D打印工艺

Resumen de: CN121798901A

本发明涉及光固化3D打印技术领域，具体公开了一种光固化复合树脂的仿生牙釉质梯度结构3D打印工艺。该工艺的核心设计在于：提供包含第一光固化组分与第二矿化前驱体组分的光固化复合树脂；在逐层打印中，先以第一波段光触发第一组分交联形成固相网络，再以第二波段光施加受控的非均匀二维光强分布，触发第二组分在所述网络空间限域下发生原位矿化反应，形成沿厚度方向连续变化的无机相；最后经温湿协同后处理提升结晶度与界面结合。本发明实现了从能量沉积梯度到微观结构梯度再到宏观性能梯度的精确编程与转化，解决了现有技术难以在单件制品内一体化构建成分、形貌、取向及力学性能连续渐变仿生结构的问题。

一种椎间融合器及其制备方法

Resumen de: CN121796096A

本申请涉及一种椎间融合器及其制备方法，涉及骨科植入的领域，一种椎间融合器，包括竖直放置的筒状的融合器主体以及固接在所述融合器主体内孔中的孔隙结构，所述孔隙结构为晶格网状。本申请提供的椎间融合器具有骨诱导功能，使得不用植骨或少量的植骨就可以达到良好的骨融合效果。

一种用于骨血管类器官构建的生物3D打印材料

Resumen de: CN121796694A

本发明涉及生物医学材料技术领域，具体为一种用于骨血管类器官构建的生物3D打印材料，含补肾活血复合提取物、生物相容性复合基材、线粒体靶向保护剂、生长因子组合物、智能缓释微球等组份，提取物由淫羊藿苷等经双频超声‑酶解提取并β‑环糊精包合；保护剂为MTP‑131与辅酶Q10复配并修饰；微球为PLGA‑明胶中空微球，接枝RGD肽且负载活性成分；生长因子由VEGF与BMP2复配并修饰；另有黏附促进单元等，适配骨血管类器官构建需求。本发明提升材料生物相容性与细胞适配性，解决成血管‑成骨偶联失衡，改善功能成分控释稳定性，优化仿生微结构，为骨血管类器官高质量构建提供保障。

一种仿骨小梁的梯度随机多孔结构的模型构建方法、白磷钙石压电骨支架及其制备方法

Resumen de: CN121809173A

本发明公开了一种仿骨小梁的梯度随机多孔结构的模型构建方法、白磷钙石压电骨支架及其制备方法，本发明所提供的模型构建方法，是以种子点投放梯度变化、体积缩放系数线性梯度变化的基于泰森多边形多孔结构设计方法；在对体心缩放过程中，对圆柱域内从轴心延径向到最外端的缩放系数进行插值计算，从而最终形成孔径延径向由内到外减小，孔棱直径延径向由内向外增大，具有仿人体骨的结构分布的随机梯度多孔结构的模型，通过设计白磷钙石陶瓷浆料配方及工艺参数，规避可能出现的过固化、开裂等问题，采用3D打印光固化打印技术制备获得具有优异结合性能的白磷钙石压电陶瓷骨支架。

一种基于3D打印的髓外定位远端截骨模块

Resumen de: CN224085378U

本实用新型一种基于3D打印的髓外定位远端截骨模块，属于膝关节手术器械技术领域，包括远端截骨模块本体，远端截骨模块本体安装于导向定位板的滑动杆上，远端截骨模块本体上设置有弹性锁紧结构，弹性锁紧结构位于滑动杆一侧，弹性锁紧结构包括按压端和夹持端，夹持端固定侧与远端截骨模块本体固定，夹持端夹持侧设置有夹持齿，夹持齿与滑动杆上的滑动齿配合设置；远端截骨模块本体底部设置有定位凹槽，定位凹槽的两侧设置有加强筋。本实用新型采用髓外定位，适用范围更广，一体化成型技术，成本大幅降低，生产周期缩短，精度更高，降低感染风险，可通过医用级尼龙材料弹性形变来实现锁紧，底部采用的加强筋结构，可增加安全性。

用于通过熔融沉积成型3D打印颜色和结构梯度陶瓷的热端

Nº publicación: CN121794105A 03/04/2026

Solicitante:

香港大学

Resumen de: WO2025060867A1

A hot end (16) for a fused deposition modeling (FDM) printer has two entrances for low-fluidity materials that may differ from each other by color and/or structure. Two separate channels (21a, 21b) of the hot end (16) lead from the entrances to a common end at a central tube (25). The two channels (21a,21b) are in the form of two special angle-skewed tubes that meet at their ends and that narrow gradually from the extruders (19') toward their ends. The central tube (25) extends from the ends of the channels (21a, 21b) to an nozzle (26). An SK type static mixer (24) is located in the central tube (25) and a heating unit (11) surrounds the hot end (16). A controller (15) operates the two extruders (19') that supply the low-fluidity materials to the two entrances of the hot end (16) in such a way as to produce ceramic (e.g., zirconia) objects that have 3D color and structural gradients.