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111
results.
Updated on
24/12/2025 [07:07:00]
Results 75 to 100 of 111
Absstract of: US2025339611A1
The present disclosure relates to the use of a PFAS-free cannula in delivering a fluid medication, such as insulin, to a subcutaneous site. The cannula comprises polycarbonate polyurethane polysiloxane (PC-PU-PS), wherein the cannula is configured for subcutaneous insertion into the tissue of the individual in need thereof. The disclosure includes methods for administering insulin using the cannula and infusion devices comprising the cannula.
Absstract of: US2025339617A1
Exemplary embodiments may modify the cost function parameters based on current and projected mean outcomes in blood glucose level control performance. The exemplary embodiments may modify the weight coefficient R for the insulin cost so that the value of R is not fixed and is not based solely on clinical determined values. Exemplary embodiments may also adjust the cost function to address persistent low-level blood glucose level excursions for users. The exemplary embodiments may reduce the penalty of the insulin cost by the sum of the converted insulin cost of the glucose excursions above target for a period divided by a number of cycles of average insulin action time. The AID system reduces the insulin cost by the lack of insulin in previous cycles.
Absstract of: US2025339060A1
Devices, systems and methods for blood glucose monitoring. The device includes a light emitter, configured to emit light signals; a light receiver, configured to receive the reflected light signal; a controller, configured to operatively connect with the light emitter and the light receiver; and an enclosure. The light signal comprises a first light signal having a first wavelength of about 940 nm, a second light signal having a second wavelength of about 1350 nm, and/or a third light signal having a third wavelength of about 1500 nm, wherein the controller comprises an operating module, and further comprises or operatively connects with a data processing system comprising a machine learning module that analyzes the data signal to generate an output data. The devices, systems and methods are non-invasive and monitor blood glucose levels in real time with high accuracy.
Absstract of: WO2025231209A1
A computing system, a computer implemented method, and a wearable computing device to predict insulin resistance in a wearer of the wearable computing device without requiring additional invasive testing other than test data that may already be available, although not required, is provided. For instance, a machine-learned model is trained to predict insulin resistance in the wearer of the wearable computing device based at least in part on non-invasive biometric data associated with the wearer. Then, one or more non-transitory computer-readable media cause the computing system to perform operations via one or more processors. The operations include receiving the non-invasive biometric data from one or more sensors associated with the wearable computing device; and implementing the machine-learned model to determine if the non-invasive biometric data associated with the wearer is indicative of insulin resistance.
Absstract of: US2025341624A1
A system for millimeter RADAR object recognition and classification using sub-band frequency interference and resonance effects from primary targets signals and reflected signals from secondary target preferably in the form of Wideband Chaos Generating Material (WCGM) objects, preferably detecting frequency dependent absorbing material, frequency dependent resonance effects from the second and primary target objects, frequency signal resonance effects caused by water molecule dipole effects in different sugar solutions, impedance of material, shape of metamaterial, and interference effects due to combination of signal sources resulting in a wider range of transmitter and scanning frequency band for RADAR based interrogation of target objects. The RADAR system makes opportunistic use of traditionally seen problematic interference signals, as extra signal sources providing extended range and frequency bandwidth for frequency-based interrogation of target object signatures in a frequency-intensity plane, a frequency-polarization plane, and a frequency-phase shift plane for doppler effects.
Absstract of: EP4643774A1
Provided is an implant apparatus for a continuous glucose monitor. The implant apparatus includes a housing assembly and a driving assembly disposed in the housing assembly. The housing assembly includes an outer housing. The outer housing has an opening at an end of the outer housing. The driving assembly has a locked state in which the driving assembly is fixed relative to the outer housing and a triggered state in which the driving assembly is movable towards the opening. The implant apparatus further includes a trigger. The outer housing includes a guiding channel located at a side wall of the outer housing and extending towards the opening. The trigger is movable along the guiding channel towards the opening and has a first position and a second position relative to the outer housing, to enable the driving assembly to switch from the locked state to the triggered state. A triggering direction of the trigger is oriented towards the opening, while a direction of a force applied by fingers of a user when the user holds the outer housing is oriented inwards in a radial direction of the outer housing. Force application directions of the two actions are perpendicular to each other. As a result, a probability of the user accidentally triggering the trigger when holding the outer housing is reduced, which reduces a risk of accidental triggering of the implant apparatus, improving use experience.
Absstract of: AU2023415722A1
Certain aspects of the present disclosure relate to a monitoring system comprising a continuous analyte sensor configured to generate analyte measurements associated with analyte levels of a patient, and a sensor electronics module coupled to the continuous analyte sensor and configured to receive and process the analyte measurements.
Absstract of: EP4643777A1
Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.
Absstract of: EP4643910A1
The present disclosure relates to a self-lubricating cannula for use in delivering a fluid medication to a subcutaneous site. The self-lubricating cannula comprises polyether block polyamide and an additive configured to facilitate the manufacture of a tipped self-lubricating cannula. The present disclosure also provides a method of making a self-lubricating cannula and a method of administering insulin using a self-lubricating cannula.
Absstract of: EP4643911A1
The present disclosure relates to the use of a PFAS-free cannula in delivering a fluid medication, such as insulin, to a subcutaneous site. The cannula comprises polycarbonate polyurethane polysiloxane (PC-PU-PS), wherein the cannula is configured for subcutaneous insertion into the tissue of the individual in need thereof. The disclosure includes methods for administering insulin using the cannula and infusion devices comprising the cannula.
Absstract of: WO2024211880A2
A method of therapy escalation for patients with diabetes includes receiving glucose data of a user from an in vivo glucose monitoring device, receiving first therapy information of a first therapy, wherein the first therapy includes basal insulin, calculating one or more glucose metrics based on the received glucose data, titrating a dose of the basal insulin based on the one or more glucose metrics, and determining overbasalization based on one or more of the glucose data and the first therapy information. Advantageously the system can regularly monitor glucose control of a user, detect overbasalization, provide frequent therapy intervention and adjustment, decrease a duration of intervention, and increase user adherence, outcomes, and satisfaction.
Absstract of: CN120859484A
Applicators and assemblies for insertion into an in vivo analyte sensor are provided. Wherein the assembly includes an insert, a first cradle assembly, a retraction spring, and a second cradle assembly, where the first cradle assembly, the retraction spring, and the second cradle assembly are configured to advance in a distal direction toward the skin of the subject from a proximal position located entirely within the interior of the insert to a distal position. The applicator includes an analyte sensor, a sensor electronics carrier, and a sharpening carrier, where the sensor electronics carrier and sharpening carrier are configured to advance from a first location within the applicator spaced from the skin surface to a second location adjacent the skin surface upon application of a first force to the applicator in a first direction. Also included is an applicator assembly for inserting an in vivo glucose sensor into a subject. The present disclosure provides a reliable sensor insertion device, for use in conjunction with a dermal sensor, easy to use by a patient, and less prone to error.
Absstract of: CN120878042A
The invention relates to a blood glucose monitoring control system and a blood glucose monitoring control method, and belongs to the technical field of blood glucose monitoring instruments. The system comprises a multispectral sensing module (comprising a 480nm/660nm dual-wavelength camera and an mmu SORS sensor), a wearable multi-modal monitoring unit (integrating a blood glucose sensor and seven physiological parameter acquisition assemblies), a blood glucose metabolism dynamics modeling module (based on a nonlinear differential equation), a dynamic blood glucose prediction engine (TCN-Transform and ST-GCN fusion architecture), an edge calculation unit (FPGA accelerated RANSAC improved algorithm), a data processing unit (data processing unit), a data processing unit (data processing unit), a data processing unit (data processing unit), a data processing unit (data processing unit), a data processing unit (data processing unit) and a data processing unit (data processing unit), a data processing unit (data processing unit) and a data processing unit (data processing unit). A closed-loop feedback actuator (Bluetooth 5.2 insulin pump regulation and control module) and a data security module (homomorphic encryption under a federated learning framework). According to the system, through multi-source data fusion and reinforcement learning optimization, the blood glucose prediction error is remarkably reduced, the emergency response time is shortened, and the accuracy and real-tim
Absstract of: CN120860361A
The invention relates to a nursing device for insulin injection and a using method thereof, and belongs to the technical field of insulin injection nursing devices.The nursing device comprises a nursing box body, a perspective area, a box body cover, a disinfection box body, a sliding cover, a separation groove and a liquid pipe swing mechanism, the perspective area is located in front of the nursing box body, and the nursing box body is movably connected with one side of the box body cover on the upper portion; when a needle cylinder of the nursing device for insulin injection is rotationally fixed and an insulin injector is in contact with a needle cylinder, an infrared detector automatically induces to drive a motor and a driving gear to rotate, so that the tail end of the needle cylinder automatically rotates through a driven gear, and the needle cylinder and the insulin injector are automatically rotationally spliced; the device is simple in structure and convenient to use, manual rotating and tightening are not needed, manual operation steps are reduced, contact between the hand and the needle head is avoided, the possibility of liquid medicine pollution is reduced, tightness between equipment can be improved through automatic rotating and fixing, and the situations of loosening, liquid leakage and the like caused by uneven force during manual operation are avoided.
Absstract of: CN120860381A
The invention provides a diabetic medicine injection positioning device which comprises a positioning waistband, a positioning plate and a binding mechanism, and the positioning plate is arranged in the positioning waistband; the binding mechanism comprises a binding band, a plug and a locking assembly, and the binding band is arranged on the outer wall of the positioning plate; the plug is connected with one end of the bandage, and the locking assembly is connected with the other end of the bandage. According to the medicine injection positioning device for the diabetic patient, through mutual cooperation of the positioning waistband, the positioning plate, the partition plate and other components, in the using process, the patient can select the proper injection position according to the positioning hole, the injection position is changed in turn, and the problem that the same part is injected repeatedly is effectively avoided.
Absstract of: CN120859487A
The invention relates to the technical field of blood drawing devices, and discloses a pneumatic endocrine diabetes blood examination blood drawing device which comprises an elastic telescopic driving mechanism and a gap type flow limiting mechanism. The pneumatic type endocrine diabetes blood examination blood drawing device can be used in cooperation with a disposable needle cylinder, a power component used for driving blood drawing can be rapidly disassembled or assembled, and therefore the use cost of the device when blood drawing is conducted on different patients is reduced, and in addition, by means of flow limitation of gas in the hole-shaped structure, the device is convenient to use and high in practicability. And the speed of blood drawing and discharging can be controlled, so that negative effects caused by too high blood discharging speed are prevented.
Absstract of: CN120870087A
The invention discloses a sweat biomarker monitoring multi-mode sensor preparation method and a multi-mode sensor. The preparation method comprises the following steps: preparing a first packaging layer; preparing a lactic acid detection piece; preparing a glucose detection piece; preparing a sweat amount measuring assembly; preparing a second packaging layer, taking a PDMS curing agent and a PDMS basic component solution, stirring, pouring into a mold, and putting into a drying oven for curing; respectively guiding the lactic acid detection piece and the glucose detection piece into the glucose content test bin and the lactic acid content test bin; placing the sweating amount measuring assembly between the first packaging layer and the second packaging layer, and packaging the second packaging layer part and the first packaging layer part into a whole by using a packaging agent; bonding a double-sided adhesive tape with a release layer to the outer surface of the second packaging layer; the second packaging layer and the double-sided adhesive tape are provided with sweat leading-in holes, and the contact liquid guide line extends out of the outer end face of the double-sided adhesive tape through the sweat leading-in holes.
Absstract of: CN223490189U
The utility model discloses an insulin pen automatic needle taking device and a sharp instrument box with the needle taking device, a rotating seat is rotatably installed in a waste needle storage box, two groups of clamping parts are symmetrically installed on the rotating seat, each clamping part is provided with a shaft body rotatably connected with the rotating seat, a pressing plate and a clamping piece, and the pressing plate and the clamping piece extend outwards from the side portion of the shaft body. An included angle is formed between the pressing plate and the clamping pieces, elastic elements are arranged between the two sets of clamping parts and the rotating base, the two sets of clamping parts are located at the needle taking opening, and under the action of the elastic elements, the clamping pieces of the two sets of clamping parts are obliquely opened outwards relative to the height direction of the rotating base. After the insulin needle is pressed downwards on the pressing plates of the two sets of clamping parts, the clamping pieces can be forced to rotate inwards so as to clamp the needle, and the driving assembly is used for driving the rotating base to rotate. The needle head dismounting device has the beneficial effects that the needle head can be automatically dismounted in a simpler and more convenient manner, so that hands are prevented from being pricked.
Absstract of: US2025331740A1
A multi-analyte sensor system is disclosed. The system includes a sensor probe that has a first set of electrodes that transduce glucose into electrical signals, a second set of electrodes that transduce lactate into electrical signals and a third set of electrodes that provide working and counter electrode functionality for the first and second set of electrodes. The system has an electronics module that electrically interfaces with the sensor probe, and includes a transceiver configured to transmit sensor data. The system also includes control circuitry communicatively coupled to the electronics module that determines a glucose state based on signals from the first set of electrodes and also determine a lactate state based on signals from the second set of electrodes. The control circuitry also generates an insulin infusion pump control signal based on signals from the first and second set of electrodes.
Absstract of: US2025331741A1
A system includes an implantable medical device configured to measure blood-glucose concentration based on cardiac activity. The system further includes processing circuitry configured to generate, based on the plurality of periods, a plurality of waveforms representative of the blood-glucose concentration. The processing circuitry is further configured to identify at least one clinically significant feature that is present in each waveform. The processing circuitry is further configured to modify one or more of the plurality of waveforms such that the at least one feature is temporally aligned across the plurality of waveforms.
Absstract of: US2025331739A1
An estimation method includes: obtaining a measurement value of advanced glycation end products of a subject; and estimating, using a correlation between a measurement value of advanced glycation end products and a blood glucose spike frequency prepared in advance, a blood glucose spike frequency of the subject based on the measurement value of advanced glycation end products of the subject obtained in the obtaining.
Absstract of: US2025331738A1
A blood glucose meter (10) comprises a main body part (11), a sensor mounting part (13), a measurement unit (14), a battery compartment (11a), a battery cover (12), a hinge (21), a lock pin (21a), and sliding surfaces (SL1, SL2). The battery cover (12) has an opening (12a) into which a jig Z is inserted during removal from the body portion (11). The hinge (21) deforms when pressed by the jig (Z) inserted through the opening (12a). The lock pin (21a) is provided at a position where it is exposed to the outside through the opening (12a), and when pressed by the jig (Z), the battery cover (12) is unlatched from the main body portion (11). When the battery cover (12) is slid along the sliding surfaces (SL1 and SL2) in a state in which the battery cover (12) is latched to the main body portion (11) by the lock pin (21a), a force in a compression direction is exerted on the hinge (21).
Absstract of: US2024423495A1
Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.
Absstract of: US2025331743A1
Techniques disclosed herein relate to adjustable glucose sensor initialization sequences. In some embodiments, the techniques may involve determining an initial amplitude of one or more voltage pulses of a sequence of voltage pulses applied to a working electrode of the glucose sensor that is at least partially inserted subcutaneously in a patient. The techniques may further involve determining a slope of one or more parameters of the glucose sensor. The techniques may further involve determining an updated amplitude of the one or more voltage pulses based on the slope of the one or more parameters. The techniques may further involve executing an initialization sequence using the one or more voltage pulses having the updated amplitude to the working electrode of the glucose sensor.
Nº publicación: US2025331781A1 30/10/2025
Applicant:
UPDOC INC [US]
UpDoc Inc
Absstract of: US2025331781A1
An artificially intelligent, voice-based method for prescribing, managing and administering at least one medication for management of type 2 diabetes to a patient. Aspects of the present disclosure provide for a system and method for configuring one or more clinical algorithms according to one or more clinical protocols to configure a conversational AI model. The conversational AI model is configured to drive a conversational AI agent configured to facilitate a plurality of multi-turn conversational interactions between a patient user and the conversational agent to enable automated initiation and titration of one or more diabetes medications for the patient.
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