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132
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Updated on
07/11/2025 [07:04:00]
Results 125 to 132 of 132
Absstract of: US2025282831A1
The present invention relates to a mutated SARS-COV-2 spike protein, a variant or fragment thereof or an mRNA or DNA encoding them for use in the prevention of COVID-19.
Absstract of: US2025283881A1
The present disclosure provides systems and processes to screen for SARS-CoV-2. This disclosure teaches specific (and different) workable ranges for starting materials in a screening process for different SARS-CoV-2 variants (e.g., the Washington isolate, Alpha variant, Gamma P.1 variant, Beta variant, Iota variant, Delta variant, Omicron BA.1 variants, etc.). As shown herein, each variant has a different combination of starting materials and incubation periods, which further demonstrates the unpredictability of success that is associated with the disclosed systems and the disclosed processes. To be clear, the general ELISA process is well known by those having skill in the art. However, what is neither well known nor intuitive are the specific parameters associated with different process steps within ELISA. Those specific parameters are the subject of this disclosure.
Absstract of: WO2024096742A1
The invention is in the field of medical treatment, and relates to a method for treating SARS-CoV-2 infections. In particular, the present invention relates to methods for prophylactic and/or therapeutic treatment of betacoronavirus infections, in particular, SARS-CoV-2 infections by means of intranasal administration or oral inhalation of polypeptides.
Absstract of: WO2024096743A1
The invention is in the field of medical treatment, and relates to a method for treating SARS-CoV-2 infections. In particular, the present invention relates to methods for prophylactic and/or therapeutic treatment of betacoronavirus infections, in particular, SARS-CoV-2 infections by means of intranasal administration or oral inhalation of antibodies.
Absstract of: JP2024020274A
To provide a drug with antiviral activity against SARS-CoV-2, which can be used for the treatment of a related disease caused by the infection of SARS-CoV-2.SOLUTION: There is provided a substituted aminopropionate compound represented by formula I, a geometric isomer, and a pharmaceutically acceptable salt thereof, a solvate thereof and/or a hydrate thereof, for treating diseases or infections caused by SARS-CoV-2.SELECTED DRAWING: Figure 1
Absstract of: EP4614150A1
The present disclosure provides systems and processes to screen for SARS-CoV-2. This disclosure teaches specific (and different) workable ranges for starting materials in a screening process for different SARS-CoV-2 variants (e.g., the Washington isolate, Alpha variant, Gamma P.1 variant, Beta variant, Iota variant, Delta variant, Omicron BA.1 variants, etc.). As shown herein, each variant has a different combination of starting materials and incubation periods, which further demonstrates the unpredictability of success that is associated with the disclosed systems and the disclosed processes. To be clear, the general ELISA process is well known by those having skill in the art. However, what is neither well known nor intuitive are the specific parameters associated with different process steps within ELISA. Those specific parameters are the subject of this disclosure.
Nº publicación: EP4613330A1 10/09/2025
Applicant:
ACAD OF MILITARY MEDICAL SCIENCES AMS PLA [CN]
Academy of Military Medical Sciences, AMS, PLA
Absstract of: EP4613330A1
An mRNA molecule is disclosed. The mRNA molecule contains a polynucleotide encoding an M1R antigen of Mpox and a polynucleotide encoding an RBD antigen of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and further contains a polynucleotide encoding an A35R antigen of Mpox. The present disclosure further discloses an application of the mRNA molecule in the preparation of an mRNA vaccine against Mpox or SARS-CoV-2. Compared to an mRNA vaccine encoding separately corresponding antigens, the mRNA vaccine encoding a fusion antigen provided by the present disclosure can induce considerable or even higher-level neutralizing antibody responses against Mpox and SARS-CoV-2, and provides 100% immune protection against the lethal challenge of ectromelia virus. The vaccine only needs to synthesize a single mRNA molecule for the encapsulation within lipid nanoparticles. Therefore, the single-component fusion mRNA vaccine has a wider application prospect than multivalent mRNA vaccine compositions.
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