Resumen de: EP4767954A1
0001 Disclosed in the present invention are an automatic determination method and system for ultrasound ablation balloon apposition. The method comprises the following steps: setting related working parameters; after a balloon moves to a target ablation area, injecting normal saline; measuring a pressure in the balloon and an impedance outside the balloon, and feeding back same to a control system; and determining whether the balloon fits with the wall of a blood vessel well. According to the technical solution of the present invention, a pressure in a balloon and an impedance outside the balloon are measured at the same time and compared with set values and set change ranges, such that accurate and automatic determination of an ultrasound ablation balloon fitting with the wall of a blood vessel is achieved, and it is ensured that ablation operation is started after the ultrasound ablation balloon fits with the wall well, thereby greatly improving the ultrasonic transmission efficiency and the ablation operation effect.
Resumen de: WO2025040266A1
The present invention relates to a hybrid supramolecular biomaterial for bioprinting and cell culture, wherein the composition is comprised of functionalized proteinaceous biopolymer and/or polysaccharide biopolymer. The present invention further relates to a biological scaffold comprised of hybrid supramolecular biomaterial and methods for the production of a hybrid supramolecular biomaterial. The present invention furthermore relates to the use of the hybrid supramolecular biomaterial for cell culture, organoid culture and/or bioprinting.
Resumen de: EP4767991A1
Embodiments relate to the methodology of direct manufacture of a customized labial/lingual orthodontic tube by using a ceramic slurry-based additive manufacturing (AM) technology. For example, a method of manufacturing customized ceramic labial/lingual orthodontic tubes by additive manufacturing may comprise measuring dentition data of a profile of teeth of a patient, based on the dentition data, creating a three-dimensional computer-assisted design (3D CAD) model of the patient's teeth, and saving the 3D CAD model, designing a virtual 3D CAD tube structure model for a single labial or lingual tube structure based upon said 3D CAD model, importing data related to the 3D CAD tube structure model into an additive manufacturing machine, and directly producing the tube with the additive manufacturing machine by layer manufacturing from an inorganic material including at least one of a ceramic, a polymer-derived ceramic, and a polymer-derived metal.
Resumen de: US2025064727A1
0000 In this specification, a new design and formulation of an expandable, gastroretentive fibrous dosage form is presented where the post-expansion mechanical strength and the drug release rate can be independently controlled. The dosage form generally comprises a fluid-absorptive, three-dimensional structural network of one or more fibers, a mechanically strengthening semi-permeable layer substantially encapsulating said fiber network, and a drug-containing solid attached to said encapsulated network.
Resumen de: EP4768054A2
An infusion pump is secured within a lockbox configured to enclose and prevent access to the infusion pump and a medication receptacle of the infusion pump, the lockbox including a lockbox control interface configured to obtain authorization for access to the lockbox from a pump communication interface of the infusion pump and enclosed within the lockbox. The lockbox control interface is electronically coupled with the pump communication interface. Transmission of a wireless credential is made to the pump communication interface by way of being received at the lockbox control interface or at the pump interface through the lockbox. The lockbox control interface receives the authorization from the pump communication interface for access based on the wireless credential and performs an action according to the received authorization for access. Action includes unlocking the lockbox or the lockbox control interface extending the pump's interface to the authorized user.
Resumen de: WO2025008779A1
The present invention relates to an advanced medication containing chitosan and azelaic acid microspheres. The present invention also relates to a process for producing the advanced medication and the use of the advanced medication in the treatment and/or prevention of skin and mucosal lesions.
Resumen de: WO2024258205A1
Provided is an implant comprising a first biodegradable polymer and a second biodegradable polymer, wherein the first biodegradable polymer comprises copolymerized polyhydroxyalkanoate (PHA), and the copolymerized PHA comprises, on the basis of the total weight of the copolymerized PHA, 0.1-50 wt% of a repeating unit derived from 4-hydroxybutyrate (4-HB).
Resumen de: WO2025042300A1
Process for methacrylation of dECM comprising placing a carbonate buffer with a concentration of 1M in the reaction vessel and heating to a temperature of 50 °C, adding dECM to the carbonate buffer to obtain a dECM solution with a concentration of 4% (w/v), sterilizing this solution by irradiation with radiation UV for 15 minutes, adding methacrylic anhydride in an amount of 0.5 mL/1g dECM and reacting at 50 °C for 1 h, then adding a phosphate-buffered saline solution to obtain a 5-fold dilution of the mixture, placing the obtained solution in dialysis tube, and then placing the dialysis tube in deionized water, this stage is carried out at a temperature of 40 °C for no longer than 4 days, after completing this stage, the solution contained in the dialysis tubes is transferred to aluminum trays and then placed at a temperature -80 °C for at least 3 hours, then the frozen solution is freeze-dried under the following conditions: shelf temperature 10 °C, pressure 0.1 mba, freeze-drying time 48 hours. The invention also relates to methacrylated dECM obtained by the above method and to the use of methacrylated dECM obtained by the above method in the bioprinting process.
Resumen de: US12667255B1
Systems and methods for generating a Mixed Reality (MR)-based optical device (e.g., MR-based slit lamp and/or MR-based microscope) are provided. The system utilizes two red, green, and blue (RGB) cameras of the MR device, substituting for operator's eyes to observe through the eyepieces of a slit lamp biomicroscope or a conventional optical microscope. The operator, wearing an MR headset, observes a three-dimensional (3D) visualization of examined eye region or, in the case of a microscope, the sample. The system enables slit lamp examinations to be conducted in a manner suitable for telemedicine, allowing multiple users to simultaneously view real-time images from the slit lamp and/or a microscope.
Resumen de: AU2022235534A1
A method, related system and apparatus are disclosed. The method is implemented by an operative set of processor executable instructions configured for execution by a processor. 5 The method includes the acts of: determining if a monitoring client N< is connected to a base through a physical connection; establishing a first communications link between the monitoring client and the base through the physical connection; updating, if necessary, the interface program on the monitoring client and the base through the first communications link; establishing a second communications link between the monitoring client and the base 10 using the first communications link; and communicating data from the base to the monitoring client using the second communications link.
Resumen de: US2019143093A1
A fluid transfer assembly is described. The fluid transfer assembly includes a unitary junction having an upstream portion and a downstream portion, the unitary junction defining a plurality of curved fluid pathways between the upstream portion and the downstream portion. The assembly also includes at least one flexible fluid conduit sealed to the junction in fluid communication with at least one of the plurality of curved fluid pathways.
Resumen de: WO2024254624A1
A device for producing a dental splint is described, comprising a computing unit (1), a thermoforming station (2) for a film on a denture model (3), and a laser cutting system (4) for cutting out the dental splint from the film. In order to configure a device of the type depicted at the outset in such a way as to enable a manufacturing process of dental splints which is as fully automated and rapid as possible, wherein, in particular, the space requirement of the required devices is minimized and complicated robotics systems for transporting the dental splints are intended to be dispensed with, it is proposed that a plurality of workstations are provided which comprise at least one 3D printer (5) for producing the denture model (3) on a workpiece carrier (10), the thermoforming station (2), a severing device (6) for severing the thermoformed film from the denture model (3), and the laser cutting system (4), wherein the workstations are arranged along a transport system (7) which comprises a guide (8) and a transport means (9) which is arranged movably along the guide (8) for loading and unloading the workstations with the workpiece carrier (10).
Resumen de: US2023113714A1
Methods, systems, and devices for optical signal measurement are described. A wearable electronic device may activate a first combination of optical sensors, the first combination of optical sensors including a set of transmitter sensors and a set of receiver sensors. In some cases, one or more optical sensor of the first combination of optical sensors may be positioned under a protrusion on an inner surface of the wearable electronic device. The device may measure, at the set of receiver sensors at a first time, one or more signals from the set of transmitter sensors, determine a signal quality metric associated with the one or more signals, and select a second combination of optical sensors for use at a second time based on the signal quality metric.
Resumen de: US2024389935A1
0000 A multifunction device for improving sleep and methods of use are disclosed herein. The device can comprise an outer housing, a front panel, a front textile wrapped partially around the front panel, a plurality of LEDs within the outer housing, and an internal reflector coupled to the outer housing. The internal reflector can be configured to reflect light generated by the plurality of LEDs towards the front textile such that the light generated by the plurality of LEDs shines through the front panel and the front textile when a sleep-related program of the multifunction device is automatically initiated.
Resumen de: WO2024252214A1
Systems and methods are provided for processing image data generated by a medical imaging system such as an ultrasound or echocardiogram system using artificial intelligence and machine learning to determine a presence of one or more congenital heart defects (CHDs) and/or other cardiovascular anomalies in the image data in a manner that is agnostic to the type of imaging system, software, and/or hardware. Image data from various types imaging systems, software, and/or hardware, having various styles of imaging data generated may be processed to determine image styles. Input image data for analysis may then be processed together with representative styles of image data to generate styled input images for each style. The styled input images may be processed by an image analyzer to detect one or more cardiovascular anomalies in the styled image data, for example. Alternatively, training data may be styled and used to train the image analyzer.
Resumen de: US12670624B1
A system produces medical images that are calibrated using a calibration slate. A subject is photographed with a calibration slate shown in the image. The calibration slate includes printed colors. The printed colors shown in the captured image can be compared against standard colors associated with the slate to color calibrate the image. Various types of medical images such as images showing wounds or other skin conditions may be color calibrated using the system.
Resumen de: WO2025090666A1
A console associated with a medical device is provided. The console includes a user interface, a visual indicator separate from the user interface, and a controller. The controller is configured to control an operation of the medical device, receive data from the medical device, display an indication of the data on the user interface, and change an output of the visual indicator based, at least in part, on the data.
Resumen de: WO2025103994A1
The present invention relates to a dental or surgical handpiece (1) formed by a head (10) and a gripping handle (11), each provided with at least one integrated internal duct (2) selected from a pneumatic duct (20), a light transmission duct (23), and a blind duct (24) suitable for housing one or more electronic sensors (5), characterised in that at least one element selected from an internal shell (111) of the handle (11) and the head (11) is made by 3D printing in metal and contains the pneumatic duct (20) and/or the light transmission duct (23) and/or the blind duct (24) as an integrated internal duct (2) in a single unit.
Resumen de: WO2025117528A1
This disclosure provides polymerizable resin compositions comprising a hydrophobic polyether-containing polymerizable polyurethane compound to impart improved stain resistance to polymeric materials formed from the polymerizable resin compositions. Further provided herein are methods of producing the compositions and using the same for the fabrication of dental devices, such as orthodontic appliances.
Resumen de: CN224421222U
本实用新型提供了一种个性化囊肿塞治器,个性化囊肿塞治器由冲洗管、固位底脚和端盖组成,冲洗管与至少一固位底脚一体成型;其中,冲洗管的一端通过囊肿开窗伸入囊腔内,另一端位于唇侧空间并活动连接有密封端盖;固位底脚的一端与冲洗管外径固定连接,固位底脚的另一端设有扁平状的粘接底板,粘接底板的一侧端面设有用于与上牙外侧面粘接固定连接的固位底网结构。本实用新型采用了数字化设计并采用3D打印一体成型的冲洗管和固位底脚,不仅简化了制作流程,缩短了加工周期,还提高了塞治器的整体稳定性和固位效果。同时,冲洗管与密封端盖的活动连接设计,通过开启密封端盖即可利用冲洗管对囊腔进行冲洗,进一步提高了使用的便捷性。
Resumen de: CN122297773A
本发明公开了一种增材制造NiTi合金表面制备DCPD/PEI/SiO2‑CuS光热多功能膜层的方法以及由该方法制备的增材制造NiTi合金,涉及医用材料表面改性技术领域。该方法包括:在合金基体表面沉积DCPD膜层;将介孔SiO2材料置于无水乙醇、去离子水的混合溶液超声,加入CuS粉末分散,离心洗涤干燥并热处理,得到SiO2‑CuS改性材料;PEI溶解于二甲基乙酰胺,SiO2‑CuS改性材料均匀分散其中,得到浸提液;再将沉积DCPD膜层的NiTi合金在浸提液中浸渍提拉,完成NiTi合金表面光热多功能膜层的涂覆。本发明成功改善了NiTi合金基体的耐蚀性、生物相容性,并赋予了其表面高效的光热抑菌性能。
Resumen de: CN224421194U
本实用新型涉及口腔种植模型技术领域,具体为一种免安装替代体3D打印种植模型,包括模型本体和替代体,所述模型本体上设有定位凹腔,所述定位凹腔底部嵌设有第一磁吸件,所述替代体底部设有与第一磁吸件相匹配的第二磁吸件,所述第一磁吸件与第二磁吸件之间通过异性磁极吸附固定,且所述替代体下部还设有导向柱,所述定位凹腔内设有与导向柱配合的导向孔,并且所述替代体内部设有缓冲减震腔体。该免安装替代体3D打印种植模型通过一体成型的嵌入式结构设计,省去了传统安装步骤,提高了替代体定位精度和整体稳定性,操作简便,提升了模型的重复使用性能和制作效率。
Resumen de: CN224421245U
本实用新型涉及骨科植入器械技术领域,公开了一种用于寰椎部分切除后的缺损修复体。旨在解决现有技术中缺少寰椎假体填充内植物,取自体骨填充术后恢复时间长等问题,且钛网植入无法有效固定的技术问题。本实用新型包括得以替代寰椎的修复体,修复体上设置骨钉孔、以容纳骨钉固定接触部位;修复体包括外框架,外框架为多孔管状结构或多孔柱状结构,多孔管状结构的管腔中填充自体骨或同种异体骨或人工骨;外框架的上下端部设置匹配于枕骨髁与枢椎关节突关节的曲面,外框架内设置支撑单元。本实用新型配合3D打印技术,与对应节段、切除部位的形状匹配,从而取代被切除节段,促进寰枢椎节段的融合,有利于恢复上颈椎的生理功能。
Nº publicación: KR20260101073A 30/06/2026
Solicitante:
아주대학교산학협력단
Resumen de: WO2026141820A1
A customized tray using a shape memory material, and a manufacturing method therefor are disclosed. The customized tray using a shape memory material, according to one embodiment of the present application, may comprise a body part, which is manufactured using a shape memory material, has, in the upper surface thereof, an accommodating recess for accommodating a tooth part of a patient, and has, along the inner periphery of the accommodating recess, an impression material space into which an impression material for obtaining an impression of the tooth part is injected.