Ministerio de Industria, Turismo y Comercio LogoMinisterior
 

Alerta

Resultados 244 resultados
LastUpdate Última actualización 17/04/2026 [07:22:00]
pdfxls
Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days
previousPage Resultados 75 a 100 de 244 nextPage  

항미생물 펩티드

NºPublicación:  KR20260038283A 18/03/2026
Solicitante: 
에자이알앤드디매니지먼트가부시키가이샤
KR_20260038283_PA

Resumen de: EP4191759A1

A secondary battery (100; 101; 102; 103) includes: a power generation element (10; 310); and an exterior part (20; 320) that houses the power generation element (10; 310) in the exterior part. The exterior part (20; 320) includes a cylindrical section (21; 121; 221; 321) that includes opening portions (21a; 3221; 325a) on two opposing sides, cover terminals (22; 222; 322) that are disposed in the respective opening portions (21a; 3221; 325a), and resins (23; 323) respectively disposed between the cylindrical section (21; 121; 221; 321) and the cover terminals (22; 222; 322). The cylindrical section (21; 121; 221; 321) and the cover terminals (22; 222; 322) are respectively integrated with the resins (23; 323). Power collectors (11; 311) of the power generation element (10; 310) are electrically connected with the cover terminals (22; 222; 322), respectively.

COMPOSITIONS COMPRISING MANGANESE FOR USE IN THE TREATMENT OF A NEURODEGENERATIVE DISEASE

NºPublicación:  EP4710932A1 18/03/2026
Solicitante: 
ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI [ES]
EP_4710932_A1

Resumen de: EP4710932A1

The invention relates to composition comprising manganese, a solvate or a pharmaceutically acceptable salt thereof, for use in the treatment of a disease in a subject, wherein the subject's cells have fewer than half the number of functional endoplasmic reticulum and mitochondria contact sites than the cells from a subject not suffering from the disease, and to an in vitro method for designing a personalised therapy to a subject suffering from a disease, comprising determining the mtDNA synthesis rate in a biological sample isolate from the subject in the presence and absence of Mn.

A NASAL FLUID SAMPLE COMPRISING A Beta, PTAU AND/OR TTA

NºPublicación:  EP4710114A1 18/03/2026
Solicitante: 
NOSELAB GMBH [DE]
Noselab GmbH
KR_20260009358_PA

Resumen de: CN121399472A

The present invention relates to a nasal fluid sample obtained from a subject, the nasal fluid sample comprising one or more marker protein amyloid beta (A beta), phosphorylated Tau (pTau) and/or total Tau (tTau). The invention further relates to a nasal fluid sample comprising one or more marker proteins A beta, pTau and/or tTau for use in a method for aiding in the diagnosis of a degenerative disease of the nervous system, and to the use of a nasal fluid sample comprising one or more marker proteins A beta, pTau and/or tTau for aiding in the diagnosis of a degenerative disease of the nervous system. The invention further relates to a method for aiding the diagnosis of a nervous system degenerative disease in a subject/individual.

抗TDP-43結合分子およびその使用

NºPublicación:  JP2026509262A 17/03/2026
Solicitante: 
エイシーイミューンソシエテアノニム
JP_2026509262_A

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

三重陰性乳癌を予測および治療するための方法および組成物

NºPublicación:  JP2026509039A 17/03/2026
Solicitante: 
シービーエスバイオサイエンスカンパニーリミテッド
JP_2026509039_A

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

MTBRタウアイソフォームを検出する方法およびその使用

NºPublicación:  JP2026048659A 17/03/2026
Solicitante: 
ワシントン・ユニバーシティ
JP_2026048659_A

Resumen de: MX2022001817A

The methods disclosed herein employ unique combinations of processing steps that transform a blood or CSF sample into a sample suitable for quantifying MTBR tau species, as well as other tau species. The present disclosure also encompasses the use of MTBR tau species in blood or CSF to measure pathological features and/or clinical symptoms of 3R- and 4R- tauopathies in order to diagnose, stage, and/or choose treatments appropriate for a given disease stage, and modify a given treatment regimen.

神経細胞のシナプス形成誘導方法および該方法に用いるマイクロビーズ

NºPublicación:  JP2026048688A 17/03/2026
Solicitante: 
株式会社JiksakBioengineering
JP_2026048688_A

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

阿尔茨海默病血液标志物流式荧光发光多联检试剂盒及其应用

NºPublicación:  CN121679035A 17/03/2026
Solicitante: 
浙江默乐生物科技有限公司
CN_121679035_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

阿尔茨海默病血液标志物pTau217的化学发光检测试剂盒及其应用

NºPublicación:  CN121679036A 17/03/2026
Solicitante: 
江苏默乐生物科技股份有限公司
CN_121679036_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

慢性的ストレス状態を評価するためのバイオマーカーパネル

NºPublicación:  JP2026048281A 17/03/2026
Solicitante: 
国立研究開発法人産業技術総合研究所
JP_2026048281_A

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

一种基于单分子免疫法检测APOE3和/或APOE4的试剂组合及其应用

NºPublicación:  CN121679041A 17/03/2026
Solicitante: 
合肥国研汉因检测科技有限公司
CN_121679041_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

补体相关性疾病靶向防治全自动分析仪检测补体的试剂盒及方法

NºPublicación:  CN121679030A 17/03/2026
Solicitante: 
杭州康知生物科技有限公司
CN_121679030_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

一种免标记FRET增强型荧光组胺RNA生物传感器

NºPublicación:  CN121674405A 17/03/2026
Solicitante: 
中国农业大学
CN_121674405_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

ONOO- Multifunctional fluorescent probes for successively detection of endogenous ONOO- and mitochondrial viscosity

NºPublicación:  KR20260036808A 17/03/2026
Solicitante: 
국립강릉원주대학교산학협력단
KR_20260036808_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

Fluorescent Probes for Fluoride Ion Detection

NºPublicación:  KR20260036809A 17/03/2026
Solicitante: 
국립강릉원주대학교산학협력단
KR_20260036809_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

Composition for predicting permeability of Blood-Brain Barrier

NºPublicación:  KR20260037573A 17/03/2026
Solicitante: 
연세대학교산학협력단
KR_20260037573_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

核桃肽在制备认知功能改善剂中的应用

NºPublicación:  CN121648252A 13/03/2026
Solicitante: 
南昌大学
CN_121648252_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

神经系统疾病特别是运动神经元疾病的肽生物标志物

NºPublicación:  CN121666456A 13/03/2026
Solicitante: 
豪夫迈·罗氏有限公司
CN_121666456_A

Resumen de: US2018099049A1

Stable lyophilized therapeutic protein compositions and their methods of manufacture are provided. Specifically, the use of water as a solid cake plasticizer and protein stabilizer is described. Also, the inclusion of a multicomponent stabilizer comprising a larger molecular entity and a smaller molecular entity is described. Also, the inclusion of post-drying annealing under certain conditions improves protein stability. Proteins are predicted to remain stable over 24 months at 25° C.

响应面法优化萌芽核桃种子蛋白最佳缓冲液萃取试验方法

NºPublicación:  CN121655982A 13/03/2026
Solicitante: 
四川农业大学
CN_121655982_PA

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

TRPM7激活剂在制备阿尔茨海默病治疗产品中的应用

NºPublicación:  CN121648293A 13/03/2026
Solicitante: 
复旦大学
CN_121648293_A

Resumen de: EP1000000A1

The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.

METHODS FOR AIDING IN DIAGNOSING AND EVALUATING A TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING A COMBINATION OF GFAP AND UCH-L1

NºPublicación:  US20260072042A1 12/03/2026
Solicitante: 
ABBOTT LAB [US]
US_20260072042_PA

Resumen de: US20260072042A1

0000 Disclosed herein are methods of aiding in the diagnosis and evaluation of a subject that has sustained or may have sustained an injury to the head. For example, the present disclosure provides methods for aiding in the diagnosis and evaluation of a subject to determine whether the subject has sustained a traumatic brain injury (TBI) by detecting or measuring a combination of the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) in samples taken at various time points within 48 hours after the subject has sustained or may have sustained an injury to the head.

FRAGMENTOMICS IN CEREBROSPINAL FLUID

NºPublicación:  WO2026051992A1 12/03/2026
Solicitante: 
CENTRE FOR NOVOSTICS [CN]
WO_2026051992_A1

Resumen de: WO2026051992A1

Various embodiments are directed to the analysis of fragmentation patterns of cell-free DNA (cfDNA) circulating in cerebrospinal fluid (CSF) and the potential applications. CSF is an important liquid biopsy sample used to study the central nervous system and related disorders, such as infection and malignancies. The characterization of fragmentation patterns of cfDNA in CSF includes the size profile, end motif, cleavage profiles, and the determination of epigenetic features, including methylation. Various applications can use one or more properties of fragmentation pattern, for example, in the determination of the proportional contribution of a particular cell types in the CSF cfDNA pool. Another purpose is the diagnosis of pathology in the central nervous system, by the detection of clinically relevant DNA (e.g., tumor fraction, pathogen). DNA fragments in CSF can be analyzed in various ways, including using short-read sequencing, and/or long-read sequencer technologies.

Protein biomarkers for diseases associated with the contact activation system

NºPublicación:  AU2026201253A1 12/03/2026
Solicitante: 
TAKEDA PHARMACEUTICALS CO [JP]
AU_2026201253_A1

Resumen de: AU2026201253A1

Provided herein are methods and kits for analyzing a biological sample obtained from a subject having, suspected of having, or being at risk for a disease associated with the contact activation system. eb e b

Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof

NºPublicación:  US20260069656A1 12/03/2026
Solicitante: 
AXCELLA HEALTH INC [US]
US_20260069656_A1

Resumen de: US20260069656A1

0000 Nutritive Polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.

PRODUCTION METHOD OF NERVE CELLS DAMAGED BY OXIDATIVE STRESS AND APPLICATIONS THEREOF

Nº publicación: US20260071179A1 12/03/2026

Solicitante:

FUJIFILM CORP [JP]

US_20260071179_PA

Resumen de: US20260071179A1

An object of the present invention is to provide a method for producing nerve cells damaged by oxidative stress from a human-derived pluripotent stem cell; a culturing method for cells that allows nerve cells damaged by oxidative stress to be produced from a human-derived pluripotent stem cell; nerve cells damaged by oxidative stress; an evaluation method for a test substance, a screening method for a drug for prevention and/or treatment of a neurodegenerative disease, a screening method for a necroptosis inhibitor, and a screening method for a ferroptosis inhibitor, which use the nerve cells.According to the present invention, there is provided a production method of nerve cells damaged by oxidative stress, the method including a step a of seeding nerve cells obtained by differentiation from a human-derived pluripotent stem cell, at a cell density of 20.0×104 cells/cm2 or less by using a culture medium that substantially does not contain an antioxidant and substantially does not contain an oxidant and a step b of culturing the nerve cells by using the culture medium that substantially does not contain an antioxidant and substantially does not contain an oxidant.

traducir