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200
resultados
Última actualización
17/04/2026 [06:54:00]
Resultados 100 a 125 de 200
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: WO2024246004A1
The present invention relates to a diagnostic method (100) for diagnosing a state of a cell stack (300) of an electrochemical energy converter. The diagnostic method (100) comprises: - connecting (101) a plurality of bipolar plates (301) of the cell stack (300) to a cell voltage measurement system (311), - ascertaining (103) measurement values for each cell (303) of the plurality of cells (303) by means of the cell voltage measurement system (311), - determining (105) a characteristic value for each cell (303) of the plurality of cells (303) on the basis of measurement values ascertained by means of the cell voltage measurement system (311), - comparing (107) the characteristic value with a specified quality criterion, - outputting (109) an error message if the characteristic value does not satisfy the quality criterion, wherein the ascertaining of measurement values is carried out in a dry state of the cell stack (300).
Resumen de: WO2024246004A1
The present invention relates to a diagnostic method (100) for diagnosing a state of a cell stack (300) of an electrochemical energy converter. The diagnostic method (100) comprises: - connecting (101) a plurality of bipolar plates (301) of the cell stack (300) to a cell voltage measurement system (311), - ascertaining (103) measurement values for each cell (303) of the plurality of cells (303) by means of the cell voltage measurement system (311), - determining (105) a characteristic value for each cell (303) of the plurality of cells (303) on the basis of measurement values ascertained by means of the cell voltage measurement system (311), - comparing (107) the characteristic value with a specified quality criterion, - outputting (109) an error message if the characteristic value does not satisfy the quality criterion, wherein the ascertaining of measurement values is carried out in a dry state of the cell stack (300).
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: WO2024246004A1
The present invention relates to a diagnostic method (100) for diagnosing a state of a cell stack (300) of an electrochemical energy converter. The diagnostic method (100) comprises: - connecting (101) a plurality of bipolar plates (301) of the cell stack (300) to a cell voltage measurement system (311), - ascertaining (103) measurement values for each cell (303) of the plurality of cells (303) by means of the cell voltage measurement system (311), - determining (105) a characteristic value for each cell (303) of the plurality of cells (303) on the basis of measurement values ascertained by means of the cell voltage measurement system (311), - comparing (107) the characteristic value with a specified quality criterion, - outputting (109) an error message if the characteristic value does not satisfy the quality criterion, wherein the ascertaining of measurement values is carried out in a dry state of the cell stack (300).
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP4722195A1
Provided are: a pH-sensitive cationic lipid which can be more easily synthesized through a small number of steps without requiring any organometal reaction or use of any relatively expensive starting materials; and lipid nanoparticles including the lipid. Disclosed is a pH-sensitive cationic lipid comprising a compound represented by general formula (I) or (I'), wherein R1, Z2, s, Z1, and X are as defined in the description.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: WO2024246004A1
The present invention relates to a diagnostic method (100) for diagnosing a state of a cell stack (300) of an electrochemical energy converter. The diagnostic method (100) comprises: - connecting (101) a plurality of bipolar plates (301) of the cell stack (300) to a cell voltage measurement system (311), - ascertaining (103) measurement values for each cell (303) of the plurality of cells (303) by means of the cell voltage measurement system (311), - determining (105) a characteristic value for each cell (303) of the plurality of cells (303) on the basis of measurement values ascertained by means of the cell voltage measurement system (311), - comparing (107) the characteristic value with a specified quality criterion, - outputting (109) an error message if the characteristic value does not satisfy the quality criterion, wherein the ascertaining of measurement values is carried out in a dry state of the cell stack (300).
Resumen de: WO2024246004A1
The present invention relates to a diagnostic method (100) for diagnosing a state of a cell stack (300) of an electrochemical energy converter. The diagnostic method (100) comprises: - connecting (101) a plurality of bipolar plates (301) of the cell stack (300) to a cell voltage measurement system (311), - ascertaining (103) measurement values for each cell (303) of the plurality of cells (303) by means of the cell voltage measurement system (311), - determining (105) a characteristic value for each cell (303) of the plurality of cells (303) on the basis of measurement values ascertained by means of the cell voltage measurement system (311), - comparing (107) the characteristic value with a specified quality criterion, - outputting (109) an error message if the characteristic value does not satisfy the quality criterion, wherein the ascertaining of measurement values is carried out in a dry state of the cell stack (300).
Resumen de: NL2041427A
The present invention provides a self—assembled nanoparticle for enhancing the auxiliary gastric mucosal protective effect of piperine and a preparation method thereof. The method includes: dissolving piperine and partridge tea polyphenols, followed by mixing, adjusting a potential of Hydrogen (pH) value, heating, concentrating, purifying, and drying a mixture to obtain the self—assembled nanoparticle. The present invention successfully prepares piperine self-assembled nanoparticles, which can significantly enhance the auxiliary gastric mucosal protective capacity of piperine at a dosage of only mg/kg body weight (b.w.). In addition, the invention separates and recovers piperine and partridge tea polyphenols based on a natural deep eutectic solvent aqueous two—phase system, which not only has the advantages of large extraction capacity, simple operation, mild preparation conditions, high selectivity, greenness and high efficiency, but also overcomes the problems existing in traditional extraction and separation methods such as difficult recovery of purified products, low selectivity and low efficiency.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Resumen de: EP4721728A1
A lipid nanoparticle composition for encapsulating a nucleic acid and a preparation method therefor. In the composition, the proportion of empty lipid nanoparticles containing no nucleic acid to the total number of lipid nanoparticles, i.e., the no-load rate, is no more than 10%. According to the preparation method, the ethanol content in the system is reduced to an acceptable level during particle fusion, so that the particles are fully fused.
Resumen de: EP4721733A1
The present disclosure relates to a nucleic acid-lipid nanoparticle composition and a lyophilized preparation thereof, and further relates to a preparation method for the composition and a use of the composition. The nucleic acid-lipid nanoparticle composition of the present disclosure comprises lactate, so that the stability of nucleic acid-lipid nanoparticles is improved in a lyophilization process and a prepared lyophilized preparation. According to the present disclosure, the total time of a freeze-drying process for the nucleic acid-lipid nanoparticles can be shortened, and energy consumption and the time cost of product scale-up production can be greatly reduced; the rehydration of lyophilized nucleic acid-lipid nanoparticles is quick, and the total amount of nucleic acids, the encapsulation efficiency, and the nucleic acid integrity are high; in addition, a lyophilized and rehydrated preparation has cell transfection efficiency not significantly different from that of a non-lyophilized nucleic acid-lipid nanoparticle stock solution, and has a high in vivo immune response, even exceeding that of the non-lyophilized nucleic acid-lipid nanoparticle stock solution.
Resumen de: WO2025048714A1
There is provided a compound represented by general formula (1) for preparing lipid nanoparticles encapsulating a therapeutic, prophylactic and/or biological agent: wherein A comprises a carbohydrate and/or a derivative thereof; R1 and R2 are each independently a hydrophobic group; R3, R4, R5, and R6 are each independently H, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl; R7, R9 and R10 are each independently optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl; R8 is -O-, -S-, or -NRa-, where Ra is selected from the group consisting of H, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl; m is 0 or 1; n ≥ 1; and w ≥ 1.
Resumen de: CN121226194A
Provided herein are lipid compounds, such as compounds of Formula (I). Also provided are lipid nanoparticles and pharmaceutical compositions, each comprising a lipid compound, such as a compound of Formula (I).
Resumen de: CN119462842A
The invention belongs to the field of biological medicines, and particularly relates to affinity peptides targeting CD47 and M2 type macrophages. The amino acid sequence of the CD47 affinity peptide is shown as SEQ ID NO: 1, and the amino acid sequence of the M2 type macrophage targeting peptide is shown as SEQ ID NO: 2. The invention also relates to preparation and application of the protein. The preparation comprises the following steps: forming a dual-targeting peptide and a transmembrane fusion protein; the molecules are expressed and synthesized by using nucleic acid molecules, and particularly a polypeptide expression and nano delivery system based on an engineered cell membrane is designed. The molecule provided by the invention can be compatible with CD47 and M2 type macrophage affinity peptide, and after a nano-carrier is designed to be combined with an STING agonist, M2 type macrophages are reprogrammed, so that the anti-tumor immune response is further enhanced.
Resumen de: CN121800865A
本发明公开了安全高效的肽基可离子化脂质及其制备方法与应用。所述肽基可离子化脂质为式II所示的化合物，式II中n为1‑7的整数。基于式II所示的化合物制备的 LNP在疗效、安全性与器官特异性间达成了协同平衡，作为下一代肝脏PILOT递送平台，为临床可转化的mRNA疗法提供了关键支撑。
Resumen de: CN121796624A
本发明公开了一种基于后插入法的抗体偶联脂质纳米颗粒制备方法及其应用，具体公开了一种抗体偶联核酸‑脂质纳米颗粒的制备方法，通过该制备方法制备得到的抗体偶联核酸‑脂质纳米颗粒包封率高、PDI小、偶联率高或靶向性好。
Resumen de: CN121796574A
本发明公开了免疫激动剂及其制备方法，涉及免疫激动剂制备技术领域，所述免疫激动剂的制备方法包括以下具体步骤：S1、双靶点免疫激动剂单体制备；S2、阳离子脂质体内核制备；S3、仿生细胞膜包被和S4、成品检测。该免疫激动剂及其制备方法，配置过程中用连续流微反应器两步合成双靶点单体，通过分段精准控温的方式搭配微波强化，能够缩短反应周期，利用微反应技术实现激动剂的高效包载，避免传统批次法包封率低、粒径不均的问题,此外MDC细胞膜提取经差速离心有利于保障膜完整性，其表面CD11c标志物实现利用细胞仿生膜实现主动靶向，3:1体积比的脂质体与膜囊泡融合后，体外BMDC结合率较裸脂质体提升。
Nº publicación: CN121796588A 07/04/2026
Solicitante:
亳州学院
Resumen de: CN121796588A
本发明涉及抗菌材料技术领域，提供一种近红外光热酶三重响应协同抗菌纳米复合材料及制备方法，包括：（1）以具有近红外二区吸收的硫化铜纳米片为结构基元，通过连续水热法，依次在其表面构筑介孔二氧化硅隔离层和钨酸铋量子点外延层，形成具有Z‑scheme能带结构的核‑壳‑卫星异质结；（2）将天然抗菌酶与具有类过氧化物酶活性的过渡金属单原子纳米酶，通过共价偶联剂在异质结的介孔通道内进行定向组装，构建级联催化系统；（3）以异质结为载体，在低温、惰性氛围及预设波长可见光引发条件下，通过表面引发可控自由基聚合，在材料表面生长具有低临界溶解温度的热响应性聚合物壳层；本发明能较佳地协同抗菌。
BOPI
Sede Electrónica
