Ministerio de Industria, Turismo y Comercio LogoMinisterior
 

Alerta

Resultados 91 resultados
LastUpdate Última actualización 13/09/2026 [07:01:00]
pdfxls
Solicitudes publicadas en los últimos 60 días/Published applications in the last 60 days
previousPage Resultados 50 a 75 de 91 nextPage  

HUMAN ANTIBODIES TO MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS (MERS-CoV) AND METHODS OF USE THEREFOR

NºPublicación:  WO2026165023A1 06/08/2026
Solicitante: 
VANDERBILT UNIV [US]
VANDERBILT UNIVERSITY
WO_2026165023_A1

Resumen de: WO2026165023A1

The present disclosure is directed to antibodies binding to and neutralizing Middle East Respiratory Syndrome-Related Coronavirus (MERS-CoV) and methods for use thereof.

SARS-COV-2 REPLICATION-DEFECTIVE VIRUS SYSTEM

NºPublicación:  WO2026163027A1 06/08/2026
Solicitante: 
UNIV OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US]
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
WO_2026163027_A1

Resumen de: WO2026163027A1

Provided herein is a replication-defective coronavirus having in its genome a modification, wherein the modification results in a reduced expression of the M gene compared to a coronavirus lacking the modification.

β-LACTOGLOBULIN FOR USE AS ANTIVIRAL AGENT

NºPublicación:  WO2026163139A1 06/08/2026
Solicitante: 
HOVIONE FARM S A [PT]
HOVIONE - FARMACI\u00CANCIA S A
WO_2026163139_A1

Resumen de: WO2026163139A1

The present disclosure relates to the use of β-lactoglobulin in the treatment of a viral condition, wherein β-lactoglobulin is in its native protein state, wherein the viral condition is caused by a human Rotavirus strain or Coronavirus OC43. The present disclosure further relates to a pharmaceutical composition comprising β-lactoglobulin and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition further comprises at least one additional therapeutic agent.

SARS-COV2 MAIN PROTEASE INHIBITORS

NºPublicación:  AU2025219283A1 06/08/2026
Solicitante: 
GILEAD SCIENCES INC
GILEAD SCIENCES, INC.
AU_2025219283_PA

Resumen de: AU2025219283A1

The present disclosure relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

SARS-COV2 MAIN PROTEASE INHIBITORS

NºPublicación:  AU2025218930A1 06/08/2026
Solicitante: 
GILEAD SCIENCES INC
GILEAD SCIENCES, INC.
AU_2025218930_PA

Resumen de: AU2025218930A1

The present disclosure relates to compounds of Formula I and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

COLD-ADAPTED, LIVE ATTENUATED SARS-COV-2 VACCINE

NºPublicación:  US20260226425A1 06/08/2026
Solicitante: 
THE UNIV OF TOKYO [JP]
WISCONSIN ALUMNI RES FOUNDATION [US]
The University of Tokyo
Wisconsin Alumni Research Foundation
US_20260226425_A1

Resumen de: US20260226425A1

An isolated nucleic acid comprising a recombinant coronavirus genome having a genetic modification that provides cold-adapted growth relative to a parent virus that is not cold-adapted and a vaccine comprising the recombinant genome and methods of using the vaccine are provided.

ANTI-SARS-COV-2 MONOCLONAL ANTIBODY AND IMMUNOASSAY METHOD AND IMMUNOASSAY INSTRUMENT FOR SARS-COV-2 USING SAME

NºPublicación:  US20260226140A1 06/08/2026
Solicitante: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260226140_A1

Resumen de: US20260226140A1

Disclosed are a monoclonal antibody capable of rapidly, simply, and highly sensitively detecting and measuring SARS-CoV-2 contained in a test sample, and an immunoassay method and immunoassay device for SARS-CoV-2 using the same. The monoclonal antibody or its antigen-binding fragment includes heavy chain CDR1-CDR3 having specific amino acid sequences and light chain CDR1-CDR3 having specific amino acid sequences. The immunoassay method for SARS-CoV-2 includes performing an immunoassay of SARS-CoV-2 utilizing an antigen-antibody reaction between this monoclonal antibody or its antigen-binding fragment and SARS-CoV-2 in a sample.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

NºPublicación:  US20260227401A1 06/08/2026
Solicitante: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227401_A1

Resumen de: US20260227401A1

Disclosed is a high performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

NºPublicación:  US20260227400A1 06/08/2026
Solicitante: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227400_A1

Resumen de: US20260227400A1

0000 Disclosed is a high performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with 301aa-319aa, 301aa-320aa, or 351aa-375aa of the amino acid sequence of the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with 301aa-319aa, 301aa-320aa, or 351aa-375aa of the amino acid sequence of the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

NºPublicación:  US20260227402A1 06/08/2026
Solicitante: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227402_A1

Resumen de: US20260227402A1

0000 Disclosed is a high-performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with the RNA-binding domain in the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with the RNA-binding domain in the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF

NºPublicación:  US20260226034A1 06/08/2026
Solicitante: 
THE ROCKEFELLER UNIV [US]
The Rockefeller University
US_20260226034_A1

Resumen de: US20260226034A1

0000 Methods and compositions for treating SARS-CoV-2 and COVID-19 are disclosed. Sulfone-1H-pyrrole-2-carboxamides of the following formula 0000 0000 inhibit the SARS-CoV-2 PLpro/NSP3 protein and are therefore useful for treating SARS-CoV-2 and COVID-19.

ANTI-SARS-COV-2 SPIKE (S) ANTIBODIES AND THEIR USE IN TREATING COVID-19

NºPublicación:  EP4784613A2 05/08/2026
Solicitante: 
NOVAVAX INC [US]
Novavax, Inc.
CN_122029189_PA

Resumen de: CN122029189A

The present invention provides antibodies that bind to the SARS-CoV-2 spike (S) protein. The invention further relates to pharmaceutical compositions, immunotherapeutic compositions and methods of using the above antibodies that bind to the SARS-CoV-2 spike (S) protein.

ANTIBODY SPECIFICALLY BINDING TO IL-10 RECEPTOR AND USE THEREOF

NºPublicación:  US20260217840A1 30/07/2026
Solicitante: 
IUCF HYU INDUSTRY UNIV COOPERATION FOUNDATION HANYANG UNIV [KR]
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
US_20260217840_A1

Resumen de: US20260217840A1

The present invention relates to an antibody specifically binding to an IL-10 receptor and use thereof. The antibody targets IL-10 signaling and has an excellent effect of suppressing cytokine storm and excessive inflammation in severe inflammatory infectious diseases, and in particular, can be effectively used in suppressing inflammatory responses in severe SARS-CoV-2 infection and fatal SFTSV infection.

TREATMENT OF CHEMOSENSORY DYSFUNCTION FROM A CORONAVIRUS INFECTION

NºPublicación:  US20260216194A1 30/07/2026
Solicitante: 
CYRANO THERAPEUTICS INC [US]
Cyrano Therapeutics, Inc.
US_20260216194_A1

Resumen de: US20260216194A1

Disclosed herein are methods of treating a taste and smell disorder caused by a viral infection in a subject, comprising administering to the subject a phosphodiesterase inhibitor. Also disclosed herein are methods of treating taste and smell loss from COVID-19 by administering a phosphodiesterase inhibitor to a subject in need thereof.

A method of preventing and treating disease with transformed microbes

NºPublicación:  US20260216253A1 30/07/2026
Solicitante: 
EKEMA GEORGE MBELLA [US]
Ekema George Mbella
US_20260216253_A1

Resumen de: US20260216253A1

The covid-19 coronavirus has killed more than 5,129,829 people, globally, out of about 255,098,687 infected. About 10 million persons died from cancer in 2020, with 19.3 new cases diagnosed. About 409,000 persons died of malaria in 2019. And none of these diseases made the WHO's list of top 5 deadly diseases of 2019. Modern medicine has made tremendous progress in the prevention and treatment of disease, but the crashing of the covid-19 coronavirus and the extremely high burden of the top deadly diseases point to the urgency of radical and totally disrupting inventions in medicine. Indeed, to effectively overcome the current burden of deadly diseases we need an agile platform with exponentially better efficacy and predictability. The world is in dire need of a new medicine platform that totally and radically disrupts the current healthcare systems and the traditional ways of preventing and treating disease. The present invention does that.The present invention uses transformed microbes, targeted to one or more mucosal surface, to prevent and treat just about any disease of importance. The current means of disease prevention relies on vaccines. As we have seen from countless failures and booster shots, vaccines have extreme limitations and increasingly fewer following. Firstly, vaccine development is unpredictable, lengthy and costly. An important lesson of the covid-19 pandemic is that waiting for several months or years to develop a vaccine, while a disease ravages the popul

Treatment of symptomatic viral disease

NºPublicación:  AU2026205425A1 30/07/2026
Solicitante: 
SYNACT PHARMA APS
SynAct Pharma ApS
AU_2026205425_A1

Resumen de: AU2026205425A1

Abstract Provided is a composition comprising a phenyl pyrrole aminoguanidine derivative for use in a method of treating viral disorders and diseases, including symptomatic viral disorders and diseases, including symptomatic COVID-19. 5 Abstract ul b s t r a c t u l

CORONAVIRUS ANTIBODIES AND THERAPEUTIC USES THEREOF

NºPublicación:  US20260217797A1 30/07/2026
Solicitante: 
TAKEDA PHARMACEUTICAL CO LIMITED [JP]
Takeda Pharmaceutical Company Limited
US_20260217797_A1

Resumen de: US20260217797A1

Disclosed herein are antibodies that bind to coronavirus spike protein (e.g., SARS-CoV-2 spike protein), and methods of use thereof (e.g., treatment of subjects infected with SARSCoV-2).

MEMBRANE-BASED, IN-GEL LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) SYSTEM AND METHOD FOR DETECTING MICROBES

NºPublicación:  ZA202304107B 29/07/2026
Solicitante: 
CALIFORNIA INST OF TECHNOLOGY [US]
CALIFORNIA INSTITUTE OF TECHNOLOGY
WO_2022115187_A1

Resumen de: ZA202304107B

Disclosed herein is a membrane-based, in-gel loop-mediated isothermal amplification (LAMP) system, kit and method for detection of a target microorganism in a sample suspected of containing the microorganism. LAMP reagents, a lysing agent and a hydrogel are placed together on a filter membrane loaded with a pre-filtered sample. The hydrogel polymerizes over a short time to immobilize any target DNA/RNA particles on the membrane. The system may include a compact, portable device that integrates heat incubation and fluorescence illumination, and also a cloud-based smartphone image analysis application for quantitative results interpretation. If target DNA/RNA are present in the sample, fluorescent amplicons are produced as a result of LAMP reaction. The target microorganisms are detected by visually detecting the presence or absence of the amplicons. The method may be employed for rapid and inexpensive point-of-use (POU) absolute quantification of SARS-CoV-2 in environmental water or wastewater samples with high sensitivity.

Voice amplifier that amplifies a human voice from a microphone through a mobile device and internal speaker

NºPublicación:  US12695826B1 28/07/2026
Solicitante: 
STUDESVILLE MAROLD OWEN [US]
Studesville Marold Owen
US_12695826_B1

Resumen de: US12695826B1

A voice amplifier that amplifies volume of a human voice from a microphone through a mobile device by utilizing a speaker that is communicably connected to the mobile device is disclosed. The voice amplifier is designed for a mobile device, such as a smart phone or a tablet computing device. The voice amplifier purely amplifies the voice from a wired or non-wired microphone through a phone operating system and hardware components and other modules of the mobile device, such as by utilizing the phone speaker and/or an optional wireless or wired speaker. Essentially through a voice amplifier mobile app, a voice can be amplified simply with the touch of one icon. The concept is for people wearing masks due to COVID-19 and future other viruses, and/or dusty, toxic, or otherwise unhealthy air environments where masks are needed, to continue to wear their mask but be able to communicate clearly.

Application of Shenling Baizhu in Preparation of Medicine for Treating Neuropsychiatric Symptoms of Recovered COVID-19 Patients

NºPublicación:  US20260207693A1 23/07/2026
Solicitante: 
BEIJING REDSUN PHARMACEUTICAL CO LTD [CN]
BEIJING REDSUN PHARMACEUTICAL CO.,LTD.
US_20260207693_A1

Resumen de: US20260207693A1

0000 An application of Shenling Baizhu in the preparation of a medicine for treating neuropsychiatric symptoms of recovered COVID-19 patients.

MULTIPLEXED COVID-19 PADLOCK ASSAY

NºPublicación:  US20260209831A1 23/07/2026
Solicitante: 
ELEMENT BIOSCIENCES INC [US]
Element Biosciences, Inc.
US_20260209831_A1

Resumen de: US20260209831A1

Methods and systems for detecting the presence of a target nucleic acid sequence in one or more samples of a plurality of samples are described. The methods may comprise the use of linear barcoded nucleic acid probes that, upon hybridization to a target nucleic acid sequence, may be ligated to circularize the probe molecule, amplified, and sequenced. The use of a probe-specific barcode integrated into the nucleic acid probe molecule, and sample-specific barcodes that may be incorporated into the nucleic acid probe molecule or added during the amplification step, enable large-scale multiplexed assay and sample processing.

Methods for Bicameral, CNS+ Treatment of CNS, Cardiovascular, Metabolic and Other Disorders

NºPublicación:  US20260207714A1 23/07/2026
Solicitante: 
CORNETT GLENN [US]
Cornett Glenn
US_20260207714_A1

Resumen de: US20260207714A1

0000 Safe, effective, disease-modifying treatments—and especially, optimized treatments—for Alzheimer's and many other CNS, cardiovascular, metabolic and other disorders remain elusive. This is in part due to many CNS, cardiovascular, metabolic. and other disorders having underlying components on both sides of the blood-brain barrier—e.g., having CNS components as well as cardiovascular and/or metabolic and/or other non-CNS components. Respective examples in CNS, cardiovascular, metabolic and other domains include Alzheimer's disease, heart failure, diabetes and COVID-19. This is in and of itself a challenge, as most drugs (~98% of small molecules; a greater portion of larger molecules such as antibodies and peptides) do not cross the blood brain barrier appreciably, and even when they do, the chances of them having a partition coefficient that optimizes dosing in compartments on both sides of the blood brain barrier is vanishingly low. This invention addresses that challenge with a novel, bicameral, CNS+ (i.e., two-compartment, where one compartment is on the neuronal/glial side of the blood-brain barrier and one compartment is not) approach. This bicameral, CNS+ approach involves parallel 1) Intranasal, direct-to-brain delivery of drugs addressing the CNS component of a CNS, cardiovascular or metabolic disorder 2) Delivery (oral, injection or otherwise) of a cardiovascular &/or metabolic &/or other agent to the central compartment (i.e., blood and well-perfused org

IMMUNIZATION SYSTEM AND USE THEREOF, FORMULATION AND USE THEREOF, INTRANASAL VACCINE, METHOD TO INDUCE SYSTEMIC AND UPPER AIRWAY IMMUNITY AGAINST RESPIRATORY PATHOGENS

NºPublicación:  WO2026152199A1 23/07/2026
Solicitante: 
FUND ZERBINI [BR]
FUNDA\u00C7\u00C3O ZERBINI
WO_2026152199_A1

Resumen de: WO2026152199A1

The present invention refers to a novel immunization platform/system and formulation comprising the targets of neutralizing antibodies against respiratory pathogens in the presence or absence of synthetic peptides containing multiple T-cell epitopes from respiratory pathogens, particularly the receptor binding domain (RBD) of the SARS-CoV-2 Spike protein and T cell epitopes of SARS- CoV-2, wherein the immunization platform/system consists of carrier nanoparticles coated with a mucoadhesive polymer (MaP), selected as a delivery vehicle.

ANTI-SARS-COV-2 SPIKE (S) IMMUNOASSAY AND METHODS OF USE THEREOF

NºPublicación:  WO2026154387A1 23/07/2026
Solicitante: 
NOVAVAX INC [US]
NOVAVAX, INC.
WO_2026154387_A1

Resumen de: WO2026154387A1

Disclosed are methods for detecting if a biological sample (e.g., saliva, serum, blood, plasma) contains IgA antibodies against SARS-CoV-2 S glycoproteins. The method includes contacting a biological sample with a SARS-CoV-2 S glycoprotein-coated surface, contacting the surface with a secondary antibody, and detecting the secondary antibody, where if a secondary antibody is detected, the sample contains IgA antibodies against the SARS-CoV-2 S glycoprotein. Assay substrates and kits for performing such methods are also disclosed.

VIRUS TREATMENT METHODS, AND RELATED PHARMACEUTICAL COMPOSITIONS, VACCINE COMPOSITIONS AND SANITIZING COMPOSITIONS

Nº publicación: US20260207540A1 23/07/2026

Solicitante:

CASHMAN DANIEL PATRICK [US]
Cashman Daniel Patrick

US_20260207540_A1

Resumen de: US20260207540A1

0000 Pharmaceutical compositions comprising at least one calcium chelating agent such as disodium ethylenediamine tetraacetate (Na2EDTA) as an active pharmaceutical ingredient, are described that are useful for treating an infection by single stranded RNA virus, such as SARS-COV-2, are described. Development of the compositions was assisted by using a novel drug discovery method which utilizes the characterization of a common molecular mechanism in a cohort of an unforeseen clinical co-morbidly patterns identified as outliers. Reverse engineering of the outlier cohort yielded unrecognized calcium requirements for infection by SARS-CoV-2 provided a common molecular mechanism in the outlier group that enabled formulation of the new pharmaceutical compositions.

traducir