Alerta

METHOD AND SYSTEM FOR PREDICTING FIXATION PERFORMANCES OF A SCREW INSERTED INTO A MATERIAL BLOCK

Resumen de: US20260310850A1

Methods, systems, and techniques for predicting fixation performances of a screw inserted into a material block. The method comprising: receiving a three-dimensional geometry of the screw; creating a computer model of the screw and the material block taking into account the three-dimensional geometry, wherein the screw is inserted into the material block in said computer model; simulating a load being applied on the screw using the computer model; and computing fixation performances using the simulation.

HYDROGEL INK, HYDROGEL AND USES THEREOF

Resumen de: US20260306528A1

This disclosure concerns a hydrogel ink comprising lipid particles, polynucleotides loaded within the lipid particles and a bioink. In one embodiment, the lipid particles comprise extracellular vesicles. The disclosure also concerns the hydrogel thereof, and its use in treating a neural disease or condition, or regenerating a soft tissue.

DEVICE FOR AUTOMATICALLY DISPENSING MEDICATIONS AT PATIENT BEDSIDE IN HOSPITAL CONTEXTS

Resumen de: US20260306364A1

A medication automatic dispensing system in hospital context which allows the preparation of single medication and multi-medication doses for personalized therapies administering, which allows the traceability of the medications contained in the device, together with the therapy administering, and a simple and fast management of the modification of the therapy administered, and allow the traceability of the operations carried out by each health care professional, of the medications loaded and still present in the device and to allow to retrieve all the medications loaded in the device when the patient is discharged.

IMAGE GUIDED PROCEDURES

Resumen de: US20260306178A1

0000 A system includes at least one image data, a viewing device, and a three-dimensionally printed model (“TDPM”). The at least one image data is generated from an imaging device. The viewing device may have extended reality capability. The at least one image data is optionally configured as a virtual three-dimensional object (“VTDO”). The VTDO is optionally configured as an optical three-dimensional object (“OTDO”). The viewing devices provides a visualization of the VTDO or OTDO. A TDPM is generated from a three-dimensional printing apparatus utilizing the at least one data image file (“image data”), by way of a VTDO or optionally a configuration thereof (e.g., a three-dimensional object, “TDO”). The viewing device harmonizes by co-locating the visualization (e.g., VT-DO or OTDO) with the TDPM.

METHODS AND SYSTEMS FOR REMOTE DISTANCE PRINTING

Resumen de: US20260306236A1

The present invention introduces a new concept in additive manufacturing (AM) by printing remotely without direct access to printing locations. Common energy sources in AM, heat and light, have small penetration into an optically opaque medium. However, the present invention introduces a deep penetration access to the printing medium using acoustic waves. Acoustic wave patterns create chemically active regions in which the printing material is solidified. The printing material may be a heat curing polymer or polymer composite. This concept introduces a new paradigm in non-invasive/minimally invasive bio-printing inside body, without open surgery, which is proved experimentally in this patent. In addition, a new concept of printing underneath solid and opaque shells with industrial application especially in aerospace is introduced, generated individually with dimensions smaller than those currently achieved;

MEDICAL DEVICE INSERTION WITH CONTOUR MAPPING

Resumen de: US20260306841A1

A method, comprising advancing, as part of an implantation procedure into a human, at least a first portion of an electrode array into a cavity in a human during a first temporal period, providing information to a computer system, the provided information including spatial based data relating to the electrode array during the implantation procedure of the electrode array into the human, receiving information based on an evaluation by the computer system of the provided information, the evaluation having used the spatial based data to estimate a feature of the cavity, the received information being an indication of proximity between the electrode array and the feature of the cavity and at least one of completing the implantation procedure including leaving the electrode array at its current location based on the received information or moving the electrode array based on the received information.

Dose Divider

Resumen de: US20260306750A1

0000 A dose divider for releasable attachment to a plunger rod of a syringe comprises first and second arms. A front portion of the first arm and the front portion of the second arm form a channel therebetween for receiving the plunger rod. A resilient hinge pivotably couples the first arm and the second arm such that the dose divider is reversibly movable between first and second configurations. When the dose divider is in the second configuration, the dose divider is configured to receive the plunger rod in the channel through an opening formed between the front portions of the first and second arms. The channel has a shape configured to receive a specific outer shape of the plunger rod. The front portions of the first and second arms are closer when the dose divider is in the first configuration than when the dose divider is in the second configuration.

A CUSTOMIZED ACETABULAR CAGE WITH INTEGRATED AUGMENT

Resumen de: US20260306267A1

0000 The present invention relates to a customized acetabular cage. More particularly, the present invention relates to a hip or acetabular cage which has integrated with it the bone augment required for a particular hip arthroplasty surgery. The augment is integrated into the acetabular cage in a seamless manner. The present hip cage is further provided with flanges having minimum dimensions which reduce the requirement for incision. The seamlessly integrated bone augment reduces the overall size of the implant and also ensures a perfect fit.

Methods and Apparatus for Benchmarking Compliance

Resumen de: US20260311852A1

0000 A system (100) monitors performance associated with home medical equipment. The system may include a non-transitory computer-readable medium that stores information for each of a plurality of patients. At least one processor may be configured to receive, from a plurality of HME devices, device usage of the plurality of patients. The processor may determine whether at least one of the plurality of patients is a compliant patient by comparing the device usage of the at least one patient to a device usage requirement. The processor may receive a filter criterion, from a user, the filter criterion concerning the information. A performance indicator may be output to the user, based on a number of compliant patients whose information meets the filter criterion.

ASSISTED POSITIONING OF A REPOSITIONABLE STRUCTURE

Resumen de: US20260306202A1

A system includes a base, a proximal repositionable structure supported by the base and a distal repositionable structure having a proximal portion supported by the proximal repositionable structure and a distal portion. An actuator system is configured to move the base, the proximal repositionable structure, and the distal repositionable structure. A control system is coupled to the actuator system and is configured to facilitate external repositioning of the distal portion that moves a control feature relative to the base frame, detect first repositioning and based on a first geometric parameter characterizing the control feature after the first repositioning, determine a first base movement of the base and a first structure movement of the proximal repositionable structure, wherein performing the first base movement and the first structure movement together moves a reference feature relative to the control feature, the reference feature fixed relative to a portion of the proximal repositionable structure.

SPINNING SINGLE ELEMENT ULTRASOUND TRANSDUCER AND FOCUSING TECHNOLOGY

Resumen de: US20260306060A1

0000 Systems and methods comprising a spinning, intravascular ultrasound transducer in a catheter are employed to optimize imaging via, for example, imaging frequency, acoustic aperture size, mechanical, physical, and/or electronic focusing. The effective focus for each individual scan line is modified, for example, by a phase sensitive combination of a plurality of neighboring scan line signals via properly adjusting amplitude, phase, and/or time axis adjustments.

METHOD FOR MONITORING THE SPATIAL DEVIATION WITH RESPECT TO A PLANNED SURGICAL PROCEDURE

Resumen de: US20260306177A1

The present invention relates to a system comprising a processor, the system characterised by the processor having access to a planned surgical procedure comprising one or more three-dimensional (3D) images corresponding to one or more predefined states of the planned surgical procedure in a body portion, the processor is configured to execute instructions to perform the following steps of a method for monitoring the spatial deviation with respect to a planned surgical procedure: a) receiving one or more image of the body portion obtained by an intraoperative imaging device wherein the one or more image is associated to a certain predefined state of the planned surgical procedure; b) superimposing the one or more received images of step a) with the corresponding section of the one or more 3D image of the planned surgical procedure associated to the same predefined state; and c) determining the spatial deviation of the surgical procedure results with respect to the planned surgical procedure from the superimposition of the images of step b). The present invention also refers to a computer program and a method thereof.

Systems and Methods For Determining Neurological Condition Based On Surface Biopotentials

Resumen de: US20260306028A1

0000 Systems and methods for gesture control using biopotential sensing wearable devices are described. The system may include a processing pipeline configured to receive and process user biopotential data. The processing pipeline may be configured to generate, based at least in part on the processed user biopotential data, an assessment of the neurological condition of the user. The processing pipeline may include a machine learning model that has been trained and/or calibrated by one or more of the following: obtaining subject biopotential data collected from a plurality of subjects; obtaining subject neurological health data from the plurality of subjects (the subject neurological health data may relate to the neurological condition; labeling the subject biopotential data using the subject neurological health data to generate labeled subject data; and/or training the machine learning model using the labeled subject data.

COMPUTATIONAL METHODS FOR SELECTING PERSONALIZED NEOANTIGEN VACCINES

Resumen de: US20260311803A1

Systems and methods for identifying a personalized tumor vaccine are provided. Somatic variants for a subject are determined and RNA sequence reads from a tumor of the subject are obtained. From the RNA sequence reads, fusion proteins are determined, each fusion protein a fusion of a portion of a first protein and a portion of a second protein. Candidate neoantigens are selected, including a first subset of candidate neoantigens encoding somatic variants and a second subset of candidate neoantigens encoding residues of the portions of the first and second proteins. A score is determined for each candidate neoantigen using a scoring function including a first scoring term that upweights candidate neoantigens having a higher relative class I MHC affinity, given a class I HLA type of the subject. Two or more candidate neoantigens are selected for the tumor vaccine as a final set of neoantigens based on the respective scores.

PREDICTIVE MEDICAL DEVICE CONSULTATION

Resumen de: US20260311857A1

Presented herein are predictive consultation techniques for use with medical devices. The techniques presented herein, sometimes referred to herein as “predictive medical device consultation techniques,” can include, for example, generation of one or more clinical predictions related to timing of future clinical appointments and/or one or more clinical predictions related to the selection of a medical device for the recipient.

AUTOMATED METHOD FOR GENERATING PROTHESIS FROM THREE DIMENSIONAL SCAN DATA AND COMPUTER READABLE MEDIUM HAVING PROGRAM FOR PERFORMING THE METHOD

Resumen de: US20260311427A1

0000 An automated method for generating a prosthesis from a 3D scan data, the method includes automatically extracting tooth information of a tooth included in the 3D scan data from the 3D scan data, automatically extracting a margin line of a prepared tooth, generating a plurality of two dimensional (“2D”) images including the prepared tooth and an adjacent tooth adjacent to the prepared tooth, automatically generating a 3D temporary prosthesis data based on the plurality of 2D images and deforming a single tooth model corresponding to the prepared tooth using the margin line and the 3D temporary prosthesis data to generate a 3D prosthesis data.

SERIOUS AND CRITICAL EVENT ECG TRIAGE AND USER INTERFACE

Resumen de: US20260306003A1

0000 A method includes detecting a first event within electrocardiogram (ECG) data, transmitting a first subset of the ECG data from a first computing system to a second computing system, displaying the first subset of the ECG data in a first window of a user interface (UI) of the second computing system, and selectively transmitting additional subsets of the ECG data from the first computing system to the second computing system as a user interacts with the UI.

BIOPRINTER

Resumen de: US20260307326A1

At a high level, disclosed herein is a bioprinter configured to fabricate a single but highly complex and multi-material regenerative scaffold compared to a more traditional approach of mass production of simple shapes. In an embodiment, printer may include a multi-head, multi-axial bio-printer for extrusion printing and laser manipulation of scaffold and/or organic materials specific to a particular tissue such as without limitation customized vascularized bone graft or joint replacement tissue. Printer may facilitate controlled deposition of cells, biologics, and/or scaffold and organic materials in controlled, mixed gradients.

SYSTEMS AND METHODS FOR IMPROVING SLEEP DISORDERED BREATHING

Resumen de: US20260311867A1

0000 A neuromodulation system is provided herein. The system can include a neuromodulation device, an electronics package, which can be part of the neuromodulation device; an external controller; a sensor; and a computing device. The neuromodulation device can include a neuromodulation lead having a lead body configured to be bent to a desired shape and to maintain that shape in order to position the electrodes relative to neural and/or muscular structures when fully deployed. The neuromodulation device can also include an antenna including an upper and a lower coil electrically connected to each other in parallel. The computing device can execute a closed-loop algorithm based on physiological sensed data relating to sleep.

AGGREGATION AND REPORTING OF SURGICAL HUB DATA

Resumen de: US20260306129A1

Surgical hub systems are disclosed. A surgical hub system comprises a surgical hub configured to communicably couple to a modular device comprising a sensor configured to detect data associated with the modular device and a device processor. The surgical hub comprises a hub processor, a hub memory coupled to the hub processor. The surgical hub system also comprises a distributed control system executable at least in part by each of the device processor and the hub processor. The distributed control system is configured to: receive the data detected by the sensor; determine control adjustments for the modular device according to the data; and control the modular device according to the control adjustments. When in a first mode, the distributed control system is executed by both the hub processor and the device processor. In a second mode, the distributed control system is executed solely by the device processor.

3D PRINTING COMPOSITION FOR BIOMATERIALS

Resumen de: US20260308309A1

0000 A 3D printing resin composition for a biomaterial and method for 3D printing the composition are disclosed. The composition comprises: (i) a pre-polymer comprising a polymeric unit of the general formula (-A-B—)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1, (ii) at least one photo-initiator, and (iii) at least one light blocker.

EDIBLE-BODY MARKING DEVICE AND METHOD THEREFOR

Resumen de: US20260307172A1

0000 An edible-body marking device (1) has a carrier device (20) that carries an edible body, a detection part (210) that detects the edible body, and a laser processing part (220) that forms a marking pattern on the edible body by using laser light. The carrier device sequentially carries the edible body to the detection part (210) and the laser processing part (220). The detection part images (210) the edible body to acquire orientation information regarding an orientation of the edible body, and the laser processing part (220) has a memory part that stores in advance multiple pieces of marking procedure information regarding formation procedures of the marking pattern in association with their respectively different pieces of the orientation information, and forms the marking pattern on the edible body according to the marking procedure information extracted from the memory part based on the orientation information acquired by the detection part (210).

Fitting Algorithm to Determine Best Stimulation Parameter from a Patient Model in a Spinal Cord Stimulation System

Resumen de: US20260306855A1

0000 Methods for determining stimulation for a patient having a stimulator device are disclosed. A model is received at an external system indicative of a range or volume of preferred stimulation parameters, which model is preferably specific to and determined for the patient. The external system receives a plurality of pieces of fitting information for the patient, including information indicative of a symptom of the patient, information indicative of stimulation provided by the stimulator device during a fitting procedure, and/or phenotype information for the patient. The external system determines one or more sets of stimulation parameters for the patient using the pieces of fitting information. In one example, training data is applied to the pieces of fitting information to select the one or more sets of stimulation parameters from the range or volume of preferred stimulation parameters in the model.

ADDITIVE MANUFACTURING PROCESS FOR PRODUCING CHEMICAL DELIVERY DEVICES USING SCREENING

Resumen de: US20260307336A1

A method of forming a chemical delivery device with an active chemical includes generating image data using an arrangement of numeric threshold values and a concentration parameter for the active chemical. The method also includes ejecting a chemical carrier including the active chemical into a portion of a plurality of cavities formed in the chemical delivery device using the image data to produce the chemical delivery device with a concentration of the active chemical corresponding to the concentration parameter.

SYSTEMS AND METHODS FOR ORTHODONTIC BRACKET DESIGN

Nº publicación: US20260306219A1 08/10/2026

Solicitante:

LIGHTFORCE ORTHODONTICS INC [US]
LightForce Orthodontics, Inc.

Resumen de: US20260306219A1

In an embodiment, a method of manufacturing customized ceramic labial/lingual orthodontic brackets by additive manufacturing may comprise measuring dentition data of a profile of teeth of a patient, based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth, and saving the 3D CAD model, designing a virtual 3D CAD bracket structure model for a single labial or lingual bracket structure based upon said 3D CAD model, importing data related to the 3D CAD bracket structure model into an additive manufacturing machine, and directly producing the bracket with the additive manufacturing machine by layer manufacturing from an inorganic material including at least one of a ceramic, a polymer-derived ceramic, and a polymer-derived metal.