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177
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Última actualización
19/12/2025 [07:10:00]
Resultados 175 a 177 de 177
Resumen de: WO2024150259A1
Method for producing a biomimetic model of fibrosis which comprises the steps of: associating at least one cell type with at least one bio-ink containing collagen, obtaining a first compound; depositing said first compound in a culture medium obtaining a first deposited compound; keeping said first deposited compound in said culture medium for a period of time longer than 1 day, preferably comprised between 2 and 5 days; adding a profibrotic factor TGF-beta (TGFP) to said first deposited compound, obtaining a second added compound; keeping said second added compound in said culture medium for an additional period of time longer than 1 day, preferably comprised between 2 and 7 days; a biomimetic model of fibrosis which comprises at least one cell type associated with at least one bio-ink containing type I collagen and at least one profibrotic factor TGFβ is added to said bio-ink.
Nº publicación: EP4648962A1 19/11/2025
Solicitante:
ALIGN TECHNOLOGY INC [US]
Align Technology, Inc
Resumen de: US2024227300A1
Methods and systems for generating support structures for additively manufactured objects are described herein. In some embodiments, a method includes receiving a digital representation of a dental appliance configured to implement a treatment stage of a treatment plan for a patient's teeth. The method can include generating a support structure arrangement configured to support the dental appliance during an additive manufacturing process. The support structure arrangement can be generated using a machine learning model. The machine learning model can be trained on a training data set including appliance data representing geometries of a plurality of dental appliances, support structure data representing geometries of a plurality of support structure arrangements, and outcome data representing outcomes of the additive manufacturing process for the plurality of dental appliances with the respective support structure arrangements.
BOPI
Sede Electrónica
