Alerta

RADIATION TREATMENT PLAN OPTIMIZATION METHOD AND APPARATUS

Resumen de: US20260325875A1

0000 A control circuit accesses patient geometry information that includes at least one target volume along with radiation treatment apparatus geometry information for a particular radiation treatment apparatus and radiation direction field geometry setup parameters that include at least one field geometry setup with at least one gantry angle, one couch angle, and one isocenter position. The control circuit can then automatically determine multi-leaf collimator (MLC) plane field geometry setup parameters for at least one radiation direction field geometry setup using a single automated multiple-field setup per radiation direction field followed by optimizing the radiation treatment plan as a function of the MLC plane field geometry setup parameters to provide an optimized radiation treatment plan.

RADIATION TREATMENT PLAN OPTIMIZATION METHOD AND APPARATUS

Resumen de: US20260325874A1

To facilitate optimizing a radiation treatment plan for a particular patient using a particular radiation treatment apparatus, by one approach, a control circuit iteratively accesses a fluence space optimization solution for a radiation treatment plan for the particular patient, generates control point parameters for the particular radiation treatment apparatus as a function of the fluence space optimization solution, determines a treatment delivery time using the control point parameters for the particular radiation treatment apparatus, and, when treatment delivery time is suboptimal, modifies the fluence space optimization solution.

SYSTEMS, DEVICES AND METHODS FOR PAIN MANAGEMENT

Resumen de: WO2026222080A1

Systems, devices, and methods for pain management and wellness are disclosed. Some methods described herein include correlating various user and sensor data to improve treatment outcomes. Devices for user treatment are also disclosed.

SYSTEMS AND METHODS FOR MAPPING INTRAORAL CAVITY PRESSURE AND TISSUE DEPTH

Resumen de: WO2026222296A1

A system for assessing breastfeeding performance may include a detection unit that may include at least one motion detection sensor, wherein the motion detection sensor may be configured to acquire motion data from a subject. The system may include a processing unit storing instructions that, when executed by the processing unit, may cause the system to acquire, from the detection unit, the motion data. The instructions may further cause the system to determine a facial deformation metric from the motion data, and to determine, based on the deformation metric and based on one or more control datum, an intraoral pressure metric. The instructions may further cause the system to convert the intraoral pressure metric into a pressure quality result. In the event the pressure quality result corresponds to a deficit associated with a breastfeeding abnormality, the instructions may cause the system to generate a deficit-responsive protocol.

MELANIN-DETECTING PULSE OXIMETER

Resumen de: WO2026222275A1

The disclosure relates to a melanin-detecting pulse oximetry system and a method of calibrating a pulse oximetry measurement. A pulse oximeter sensor obtains an oxygen saturation measurement from a patient, and a reflectance sensor positioned on a finger of the patient by a finger clamp obtains skin reflectance data at wavelengths of about 415 nm, about 515 nm, and about 630 nm. A processor receives the oxygen saturation measurement and the skin reflectance data and generates a calibrated oxygen saturation value based on the oxygen saturation measurement and the skin reflectance data. The reflectance sensor may comprise a spectrometer, and a computing device may apply a regression model and output the calibrated oxygen saturation value through a graphical user interface.

生体信号を用いて疾患予測情報を生成する方法

Resumen de: WO2025058286A1

According to an embodiment of the present disclosure, disclosed is a method for generating disease prediction information using biometric signals, which is executed by a computing device. The method may comprise the steps of: acquiring biometric signals at a diagnosis time point; acquiring past biometric signals at a previous time point before the diagnosis time point or information associated with the past biometric signals; and generating disease prediction information for the diagnosis time point on the basis of the biometric signals at the diagnosis time point and the past biometric signals at the past time point or the information associated with the past biometric signals, using a neural network model.

眼球光バイオ刺激光学部品

Resumen de: WO2025054569A1

A device providing ocular photo-bio-stimulation therapy, a biological technique to control or influence the activity of neurons or other cell types in, on or about the eye with light. As used herein ocular photo-bio-stimulation is an umbrella category of which photobiomodulation, optogenetics and phototherapy are forms thereof. The current invention relates, in part, to photobiomodulation therapy, which includes the utilization of nonionizing electromagnetic energy to trigger photochemical changes within cellular structures. The current invention relates, in part, to optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. The current invention relates, in part, to phototherapy, also known as light therapy or bright light therapy, which is a treatment that uses controlled exposure to artificial or natural light to treat medical conditions.

ELECTROMAGNETIC DROP-ON-DEMAND (DOD) TECHNOLOGY AS AN INNOVATIVE PLATFORM FOR AMORPHOUS SOLID DISPERSION PRODUCTION

Resumen de: WO2025128987A1

Described are continuous manufacturing methods using 3D printing or any similar additive manufacturing technology to produce pharmaceutical ASDs. Manufacturing methods include preparing printing ink including API and polymeric carriers. The printing ink is accurately deposited onto a deposition surface by forming printing ink droplets by using an electromagnetic DoD 3D printing device to form an ASD printed product. The ASD printed product has improved solubility and bioavailability than the API in crystalline form.

ORAL DRUG DOSAGE FORM FOR TARGETED DRUG DELIVERY BASED ON TRACKING MARKER AND METHODS OF DESIGN AND USE THEREOF

Resumen de: WO2025124483A1

Provided is an oral drug dosage form configured to be used for targeted drug delivery at a desired gastrointestinal location, methods of design and use related to the oral drug dosage form.

SYSTEM FOR PREPARING TEETH FOR RESTORATION

Resumen de: EP4825333A2

A dental overlay device includes a base (1013), connecting strut (1018), and veneer holder (1019). The base has a curvature in the form of an arch of a patient and defines a curved axis. The connecting strut has a first end attached to the base and a second end and extends in a generally orthogonal direction to the curved axis. The veneer holder has first and second ends and extends in a transverse direction to the direction the connecting strut extends. The second end of the connecting strut is attached to the veneer holder. A dental overlay device and veneer combination includes a first veneer and a second veneer prepared for mounting onto the plurality of teeth. Floss is configured for passing between the first veneer and the second veneer when the dental overlay device is mounted onto the plurality of teeth.

SYSTEMS AND METHODS FOR DELIVERING PRESCRIBED WOUND THERAPY

Resumen de: EP4826734A2

0001 Embodiments of delivering reduced pressure wound therapy are disclosed. In some embodiments, a system includes a reduced pressure wound therapy device and a remote computer. The device can be configured to apply reduced pressure to a wound of a patient according to a default reduced pressure therapy prescription. The device can be configured to monitor usage data and transmit the usage data to the remove computer for determining compliance with a reduced therapy prescription. In some cases, non-compliance can be determined due to change of the prescription from the default prescription to a prescription more suitable for treating the wound. A non-compliance notification can be transmitted to the device. The device settings can be updated to the current prescription.

GEBELER İÇİN GEBELİK HAFTASINA GÖRE DİNAMİK RİSK SKORU ÜRETEN, OPTİK DOĞRULAMALI AKILLI İDRAR STRİP TAKİP SİSTEMİ

Resumen de: TR2026016910A2

Buluş, gebelik döneminde idrar stripleri ile glikoz takibinin ev ortamında güvenilir bir şekilde yapılabilmesi amacıyla, standart idrar striplerinin optik olarak okunmasını, okunan verinin gebelik haftasına göre dinamik eşik değerleri, önceki ölçüm trendleri, ölçüm zamanı, strip geçerlilik kontrolü ve referans alan doğrulaması ile birlikte değerlendiren ve yalnızca doğrulanmış kritik risk durumunda kapalı devre bildirim gönderen bir akıllı takip sistemi ile bu sistemin çalışma yöntemini kapsamaktadır.

連続グルコース監視のための分散システムアーキテクチャ

Resumen de: JP2021089747A

To receive glucose data from a continuous glucose sensor and control the use and redistribution of the data so that the data is used in an intended manner.SOLUTION: In one aspect, a method includes: preparing data including glucose levels using a continuous glucose sensor unit; wirelessly transmitting the data relating to the glucose levels to a display device from the continuous glucose sensor unit; automatically forwarding the data relating to the glucose levels from the display device to a cloud computing architecture; and storing the data relating to the glucose levels in separate groups at the cloud computing architecture.SELECTED DRAWING: Figure 4

A medical cabinet

Resumen de: GB2645382A

A patient is provided with a wristband having a unique machine-readable patient code and medical cabinet 2. Cabinet 2 has first compartment 4 for securely containing the Patient's Own Drugs (PODs) and second compartment 6 for securely containing further medicines. Authorised persons register the patient on a computer and register PODs by entering details of each POD into the computer. Authorised persons set reminder times in the computer for administration of PODs and place PODs into first compartment 4. Optionally, further medicines are placed into second compartment 6. The computer provides a reminder to the patient at each reminder time. Upon receipt of the reminder, the patient scans the wristband using a code reader. The reading of the unique patient code initiates unlocking of the door to first compartment 4, but not second compartment 6, thereby giving the patient access to a POD. Optionally, the ability of a patient to comply with self-administration of a drug treatment regime is assessed by logging the number of times a first locker is unlocked by scanning the patient's wristband and comparing the number with the number of reminders.

注入体積検出システム及び方法

Resumen de: WO2026054777A1

A vision-enabled fluid flow rate detection system is disclosed. The system includes an image sensing device that images an infusion container supplying a fluid to an infusion pump and a pattern of markings associated with a surface of the container, and identifies a visual difference in the pattern from a default state of the pattern to determine a volume of fluid infused from the infusion container, and used to calculate a volume of fluid in the container and a flow rate of the fluid. When the amount of fluid, as determined by the vision system, differs from the amount reported by the pump, the pump's motor may be adjusted to correct the expected volume or flow rate, as needed. When a severe infusion inaccuracy is detected, an alarm or other indication may be provided, or the infusion terminated.

COMPUTING DEVICE FOR SETTING MEDICAL TREATMENT ORDER ON BASIS OF PATIENT?S CONDITION AND METHOD FOR CONTROLLING SAME

Resumen de: EP4825318A1

0001 The present disclosure provides a method and a computing device for setting a treatment order based on an emergency patient's condition. According to an embodiment of the present disclosure, a method for setting a treatment order based on an emergency patient's condition, performed by a computing device including at least one processor, comprises, when reception data of a new examinee is acquired, acquiring physiological data of the examinee via a sensing unit, analyzing the physiological data using a pre-trained neural network model to identify the new examinee's condition, and setting a treatment order for the new examinee based on a time at which the reception data of the new examinee is acquired and the new examinee's condition. The setting of the treatment order comprises setting the treatment order for the new examinee by adjusting, based on the examinee's condition, the treatment orders of the other previously registered examinees who are waiting for treatment.

FISTULA FAILURE PREDICTION

Resumen de: EP4826736A1

0001 The present invention relates to a computer-implemented method for predicting a patient's (P) fistula failure encompassing an inputting of a plurality of parameter values, into a computer system (1), wherein some of these values have been measured during one or more dialysis treatment sessions while treating the patient (P) using a hemodialysis treatment apparatus (100) and/or wherein some of these values are or have been calculated based on or derived from values having been measured during one or more dialysis treatment sessions while treating the patient (P) using a hemodialysis treatment apparatus (100). The computer-implemented method further encompasses a predicting of the probability of an event predefined as a fistula failure within a predetermined time period or within a predetermined number of treatment sessions. Moreover, it encompasses an outputting of the predicted probability.

ADMINISTRATION SYSTEM, DELIVERY DEVICE, AND NOTIFICATION DEVICE FOR COMMUNICATING STATUS OF A MEDICAL DEVICE

Resumen de: EP4825410A2

0001 An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device is a wearable automatic injector configured to be worn on the patient's skin. A delivery device of the present disclosure allows a user or patient to view the status of a container. For example, a delivery device of the present disclosure provides a simple and effective visual means of displaying fill confirmation and delivery confirmation.

对准器损坏的预测和缓解

Resumen de: CA3112338A1

Embodiments relate to an aligner breakage solution. A method includes obtaining a digital design of a polymeric aligner for a dental arch of a patient. The polymeric aligner is shaped to apply forces to teeth of the dental arch. The method also includes performing an analysis on the digital design of the polymeric aligner using at least one of a) a trained machine learning model, b) a numerical simulation, c) a geometry evaluator or d) a rules engine. The method may also include determining, based on the analysis, whether the digital design of the polymeric aligner includes probable points of damage, wherein for a probable point of damage there is a threshold probability that breakage, deformation, or warpage will occur. The method may also include, responsive to determining that the digital design of the polymeric aligner comprises probable points of damage, performing corrective actions based on the probable points of damage.

Expandable medical device

Resumen de: WO2025231436A1

An expandable prosthetic device used as a prosthesis during surgery. The expandable prosthetic device is configured for use in the extremities of a body such as, but not limited to, use in the expansion of the lateral or medial column of a foot. The expandable prosthetic device includes a drive block, a linkage block, a drive screw, a first endplate, a second endplate, and first and sets of linkages. Rotation of the drive screw causes movement of the linkage block relative to the drive block and/or movement of the first endplate relative to the second endplate.

Dental retainer

Resumen de: US12765969B1

The present invention is directed to a dental retainer. The dental retainer may comprise a retainer wire, a left bracket (or receptacle) and a right bracket (or receptacle) placed on the lower lingual side of the lower incisor teeth. The dental wire may be adapted to hold the lower teeth of a patient in place after the patient has undergone a procedure to realign the teeth. The lingual side if the left bracket may be adapted to couple to the lingual side of the bracket on lower right cuspid. The retainer wire may detachably couple to the left bracket and the right bracket such that the retainer wire is adapted to press against the lingual side of the lower incisors to retain the lower incisors in position. The retainer wire may be adapted to be removed and replaced in to clean the teeth, further adapt the wire, and be replaced for continued use. The retainer wire may be manufactured using a 3D printer.

一种脂质溶致液晶载药组合物及其制备方法与在口服递送中的应用

Resumen de: CN122937233A

本发明提出了一种脂质溶致液晶载药组合物及其制备方法与在口服递送中的应用，属于药物递送系统与功能性食品技术领域。本发明的组合物包括含单油酸甘油酯与亚油酸组成的油相、含Pluronic F127和KCl、烟酰胺的水相。本发明利用挤出式3D打印喷嘴内的高剪切流场诱导液晶畴由随机多畴结构转变为取向有序结构，实现对纳米水通道曲率与连通性的主动编程。该载体利用胃肠道天然pH梯度作为内源性触发信号，在胃部酸性环境中保持结构稳定实现缓释，在肠道中性环境中发生相变促进药物释放，同时通过再分散形成纳米胶体增强细胞吸收。本发明突破了传统液晶被动自组装模式的局限，为水溶性营养素的口服精准递送提供了绿色高效的新策略。

一种面向足底压力调控鞋垫及其逆向设计方法

Resumen de: CN122939097A

本发明公开了一种面向足底压力调控鞋垫及其逆向设计方法，涉及足部矫形辅具与增材制造技术领域。所述方法先根据增材制造设备参数与孔隙连通约束确定可制造偏移参数区间，以及对应的可实现等效模量区间，将制造约束前置；再采集使用者足底压力云图并预处理得到归一化压力场，按压力越高模量越低的逆向映射构建目标模量场，反解为三周期极小曲面薄壁结构的偏移参数场，进而生成沿鞋垫连续变化的梯度多孔薄壁结构，并按单道沉积线宽生成可变线宽逐层打印路径。本发明解决了现有鞋垫个体针对性不足、梯度薄壁结构可制造性差的问题，且能够在单一材料下实现高压区域泄力、支撑区域稳定支撑的个体化连续梯度鞋垫，可制造性好。

一种支架-屏障膜一体化引导骨再生结构及其制备方法

Resumen de: CN122937296A

本发明公开了一种支架‑屏障膜一体化引导骨再生结构及其制备方法，属于生物医用材料及口腔颌面外科骨再生医疗器械技术领域。本发明提供的支架‑屏障膜一体化引导骨再生结构，基于3D打印技术，且主体材料包含光交联水凝胶(如甲基丙烯酰化明胶）、海藻酸盐及介孔生物活性玻璃。为解决临床牙槽骨增量中成骨空间丧失（引导骨再生支架的移位、塌陷）和软组织提前长入的两大难题提供一种全新、更有效的一体化解决方案，将目前临床中最常应用的两步法（骨替代支架+屏障膜）合为一步，这种设计有望简化手术步骤，降低医师术中操作难度，具备重要临床转化前景。

一种用于3D打印的液态金属-明胶基热响应导电复合水凝胶及其制备方法和应用

Nº publicación: CN122941025A 20/10/2026

Solicitante:

湖南工业大学

Resumen de: CN122941025A

本发明公开了一种用于3D打印的液态金属‑明胶基热响应导电复合水凝胶及其制备方法和应用，本发明以甲基丙烯酰化明胶、SiO2包覆液态金属分散液、没食子酸、聚乙二醇二丙烯酸酯和引发剂为原料，利用甲基丙烯酰化明胶的温度敏感性和镓铟合金的导电性，制备得到具有热响应的导电复合水凝胶，再结合聚合的没食子酸增强了粘附性能，纳米SiO2包覆液态金属提高分散性，制备的水凝胶兼具热响应性能、皮肤界面粘附性能和导电性能，且具有优异的3D打印流变性能，能够长期、稳定地监测多种电生理信号，解决了现有导电复合水凝胶灵敏度不足、皮肤贴合性差及信号采集稳定性欠佳等问题。