Alerta

SOLID DOSAGE FORM PRODUCTION

Resumen de: US2025275927A1

The present invention provides methods of preparing solid dosage form, particularly pharmaceutical dosage forms, using extrusion and 3D-printing, as well as the solid dosage form itself, the compositions used to make said items, uses of the solid dosage forms, and containers used in their preparation.

METHOD FOR PRODUCING ORGANOIDS, ORGANOIDS PRODUCED WITH THIS METHOD, AND USE THEREOF

Resumen de: WO2025181738A1

A method for producing organoids, wherein: a hydrogel containing cells and optionally a photoinitiator is subjected to a bioprinting process at a temperature within a range of 20-30°C, a pressure within a range of 40-75 kPa, and a constant extrusion rate of 10 mm/s, wherein the printed hydrogel is directed into a vessel containing oil, and then the resulting hydrogel capsule in an oil layer is transferred to a sieve and washed with hexane and a cell medium. Organoids produced with this method, and use thereof.

SYSTEMS AND METHODS FOR PRINTING A CORE FIBER

Resumen de: US2025276489A1

A print head, system and method for producing hollow fiber structures, for example three-dimensional biological structures comprising living cells, includes a dispensing channel, a core channel converging with the proximal end of the dispensing channel, a first shell channel converging with the core channel and the dispensing channel at a focusing intersection or chamber, and a sheath flow channel converging with the dispensing channel at a sheath flow intersection or chamber located between the focusing intersection or chamber and the distal end of the dispensing channel. The diameter of the dispensing channel increases from a first diameter to a second diameter at the sheath flow intersection or chamber, and the core channel has a third diameter less than the first and second diameters. The sheath flow channel includes sheath flow sub-channels and the focusing chamber has a conical frustum shape.

FEM ANALYSIS FOR THE PRODUCTION OF DENTAL RESTORATIONS

Resumen de: EP4609823A1

Die vorliegende Erfindung betrifft ein Verfahren zum Aufbauen einer dentalen Restauration, mit den Schritten eines Bereitstellens (S101) eines dreidimensionalen Datensatzes, der die räumliche Form der dentalen Restauration und eine räumliche Verteilung zumindest eines Herstellungsmaterials innerhalb der dentalen Restauration angibt; eines Simulierens (S102) einer räumlichen Spannungsverteilung innerhalb der dentalen Restauration bei einer vorgegebenen Belastung auf Basis des dreidimensionalen Datensatzes; und eines Veränderns (S103) des dreidimensionalen Datensatzes auf Basis der simulierten Spannungsverteilung.

CONTINUOUS MID-AIR 3-DIMENSIONAL PRINTING FOR PHARMACEUTICAL DOSAGE FORMS

Resumen de: WO2024092237A1

Described are continuous manufacturing methods using 3D printing or any similar additive manufacturing technology to produce pharmaceutical dosage forms or pharmaceutical delivery devices. Manufacturing methods using hot-melt extrusion to fabricate filaments for fused deposition modeling (FDM) based 3D printing are disclosed. Methods using FDM based 3D printing to fabricate printed products suitable for pharmaceutical delivery purposes are disclosed. The printed products may have various shapes and configurations.

CURABLE COMPOSITIONS COMPRISING A POLYMERIZABLE REACTIVE DILUENT FOR FABRICATION OF ORTHODONTIC APPLIANCES

Resumen de: US2024191006A1

The present disclosure provides curable compositions comprising one or more of photo-polymerizable monomers as reactive diluents, as well as polymeric materials formed from the curable compositions. Further provided herein are methods of producing the compositions and using the same for the fabrication of medical devices, such as orthodontic appliances.

FEM ANALYSIS FOR THE PRODUCTION OF DENTAL RESTORATIONS

Resumen de: EP4609822A1

Die vorliegende Erfindung betrifft ein Verfahren zum Aufbauen einer dentalen Restauration, mit den Schritten eines Bereitstellens (S101) eines dreidimensionalen Datensatzes, der die räumliche Form der dentalen Restauration und eine räumliche Verteilung zumindest eines Herstellungsmaterials innerhalb der dentalen Restauration angibt; eines Simulierens (S102) einer räumlichen Spannungsverteilung innerhalb der dentalen Restauration bei einer vorgegebenen Belastung auf Basis des dreidimensionalen Datensatzes; und eines Veränderns (S103) des dreidimensionalen Datensatzes auf Basis der simulierten Spannungsverteilung.

Apparatus and method for 3D printing

Nº publicación: GB2638786A 03/09/2025

Solicitante:

FABRX LTD [GB]
FabRx Ltd

Resumen de: GB2638786A

3D printing of solid-dosage-forms. A printhead comprising one of an integrated powder dispenser or an integrated peristaltic pump 11, where the printhead may be interchangeable and may comprise a multi-tip array. A 3D printer comprising one or more of the printheads. The peristaltic pump may comprise a thermostatic peristaltic pump and tubing 13 for pumping at up to 160 °C, a temperature controlled chamber 12 for storing semi-solid material, and may comprise dispensing tips 15 for simultaneous printing of multiple items. 3D printing apparatus comprising the 3D printer and a build platform with integrated capsule holders and/or moulds. 3D printing apparatus comprising a conveyer belt and balance. Methods of manufacturing solid-dosage-forms comprising use of the 3D printer to print semi-solid material at up to 160 °C, fill capsules or moulds, or print multiple items simultaneously.