Alerta

METHOD OF PREPARING A DENTAL PRODUCT, DENTAL PRODUCT OBTAINABLE BY THE METHOD, ARRANGEMENT COMPRISING A DENTAL PRODUCT AND METHOD OF TREATING A DENTAL PRODUCT

Resumen de: WO2026012977A1

The present invention relates to a method of preparing a dental product having an increased ductility, the dental product comprising a polymer comprising a functional group capable of forming a hydrogen bond, the method comprising the steps of printing a dental product from a resin composition; followed by subjecting the dental product to at least one of the following procedures: (i) storing the dental product in water and/or an alcohol for at least 30 seconds at a temperature of at least 50°C, and/or (ii) storing the dental product at a relative humidity of at least 60 % and/or in an aqueous and/or alcoholic solution for at least 24 hours. The present invention further relates to a dental product obtainable by the method, an arrangement comprising a dental product, a method of treating a dental product and the use of water and/or an alcohol as a plasticizer for a dental product.

ADDITIVE MANUFACTURING USING VARIABLE TEMPERATURE-CONTROLLED RESINS

Resumen de: US20260015450A1

Provided herein are systems and processes to control multiple temperatures in additive manufacturing. Such temperature control adjusts polymer properties and facilitates processing of materials to form 3D objects. The systems and processed disclosed herein also facilitate the processing of typically difficult-to-process materials and deliver such materials to a photocuring zone configured to photopolymerize materials into 3 dimensional objects with a layer-by-layer process. Such processes can include the steps of heating a resin to a flowable temperature, applying the resin to a carrier, cooling the film to increase viscosity or to solidify the resin, and applying the film containing the resin onto an area being printed, then photocuring the film. Also provided herein are resins and related polymer materials having properties that are tunable with exposure to more than one temperature zone. The formed polymers can include multiple regions of polymer material, each independently having distinct properties. Processes and systems are also provided herein that are configured to produce polymeric materials having multiple regions with distinct properties from a single-component formulation.

3D Artificial muscle creation method using a 3D bioprinter

Resumen de: KR20260007390A

본 발명은, 제1공급관부와, 제1공급관부의 내측에 배치되는 복수의 제2공급관부로 구성된 3D바이오 프린터를 이용한 인공근육 생성방법에 있어서, 제1공급관부로 제1근육 생성물질을 공급하고, 제2공급관부로 제2근육 생성물질을 공급하는 공급 단계와, 제1공급관부와 제2공급관부를 통해 배출되는 제1근육 생성물질과 제2근육 생성물질을 경화시키는 경화 단계를 포함하며, 공급 단계에서 제1공급관부를 통해 공급되는 제1근육 생성물질의 공급 속도가 제2공급관부를 통해 공급되는 제2근육 생성물질의 공급 속도보다 빠른 속도를 가지는 3D바이오 프린터를 이용한 인공근육 생성방법을 제공한다.

歯科分野で使用するためのバイオマテリアル

Resumen de: CN120615008A

The present invention relates to a crosslinkable polymer composition comprising at least one calcium phosphate, at least one biocompatible and biodegradable organic polymer or a precursor thereof, and Zn-ZnO core-shell particles, to a biomaterial obtainable by photopolymerization of such a crosslinkable polymer composition, and to a method for preparing the same. To a method for preparing such a composition and such a biomaterial, and to the use of such a biomaterial in various applications in the field of health.

DRY POWDER INHALER FOR PULMONARY OR NASAL DELIVERY

Resumen de: EP4679437A2

A dry powder inhaler (1) has a chamber (12) for housing a capsule and an inhalation channel (22), the chamber (12) is shaped in order to determine an agitated motion of the capsule in the chamber (12) during an inhalation of a user, the inhaler (1) comprises a capsule-piercing mechanism (30) arranged to pierce a capsule in the chamber (12) and a monitoring system (40) comprising an accelerometer (42) to measure mechanical oscillations determined at least by the agitated motion and by a flow of air through the chamber (12) and/or inhalation channel (22), the accelerometer (42) being arranged on a printed circuit board (48) arranged to transmit the mechanical oscillations from the inhaler body (10) to the accelerometer (42); a detection unit (44) arranged to detect an activation of the capsule-piercing mechanism (30); and an electronic processing unit (46) configured to receive signals from the detection unit (44) and from the accelerometer (42). Reception of a signal from the detection unit (44) triggers processing of signals from the accelerometer (42) by the electronic processing unit (46) in order to generate inhalation data. The monitoring system (40) is integrated in the inhaler body (10) or in a monitoring module (41) that is permanently or detachably attached to the inhaler body (10).

NEW CUTOUT FOR ELASTIC ALIGNERS, METHOD OF MANUFACTURING SAME AND SYSTEM FOR ORTHODONTIC TREATMENT

Resumen de: EP4678137A1

This patent description outlines the comprehensive details of the improved elastic cutout in orthodontic aligners, comprising a polymeric material formed with multiple cavities configured to apply a load to at least one tooth to cause movement of said tooth. The integrated cutout for elastics is positioned on the aligner, wherein cutout for elastics is configured to retain an elastic band and wherein cutout for elastics is configured to be connected with the button arranged on the opposite aligner. The cutout for elastic is integrated into aligner and cutting of the cutout for elastic is performed on bubble-like element. This invention also provides a method for manufacturing of the cutout for elastics and the orthodontic treatment system which comprises the aligner with incorporated cutout for elastics, the opposite aligner on which a secure lock-up mechanism is fixed and elastic band which specifically is designed to create an elastic connection between the secure locking mechanism and the cutout for elastics.

APPARATUS AND PROCESS FOR MANUFACTURING A MEDICAL DEVICE AT POINT OF CARE

Resumen de: AU2024231554A1

Aspects in accordance with the present invention pertain to an apparatus for manufacturing a medical device, said apparatus comprising at least two production modules, at least one integrating element, and at least one inspection gate, wherein the production module is configured to process the medical device, a medical device part, a medical device accessory, a medical device preform, or a raw material; the integrating element is configured to, between any two of the production modules, move the medical device, the medical device part, the medical device accessory, or the medical device preform; and the inspection gate is configured to, outside the production module, subject the medical device, the medical device part, the medical device accessory, or the medical device preform, to an inspection technique according to a predetermined inspection mode, the operations of said production modules, said integrating element, and said inspection gate, being administered by a controlling software, and said apparatus is constructed as a ready-to-transport compact unit.

A MICROFLUIDIC DEVICE AND A METHOD OF FORMING THEREOF

Resumen de: AU2024233284A1

A method of manufacturing a patient-specific microfluidic device and a patient-specific microfluidic device are provided. The method includes obtaining three-dimensional (3D) information associated with vascular geometry in a region of interest from one or more clinical images associated with a patient, and fabricating the patient-specific microfluidic device using said 3D information. The patient-specific microfluidic device includes a flow channel having a geometry that substantially corresponds to the vascular geometry in the region of interest.

BIOMIMETIC SCAFFOLD FOR PERIPHERAL NERVE INJURIES

Resumen de: EP4678400A2

The disclosure relates to a nerve repair scaffold comprising: a sheath having a proximal end and a distal end, the sheath housing a plurality of microchannels traversing the sheath from the proximal end to the distal end, wherein the microchannels are configured to allow growth of nerve tissue; and a first overhang at the proximal end and a second overhang at the distal end.

향기 방출 시스템

Resumen de: AU2024276549A1

Methods of manufacturing a porous device for diffusing a fragrance using additive manufacturing including iteratively spreading a loose powder and selecting at least one process parameter to create a porosity within the porous device adapted to carry the fragrance from a fragrance reservoir to an exterior surface of the porous device. An additively manufactured device for diffusing a fragrance includes a diffuser having a plurality of pores defining a porosity of the diffuser, the porosity defining at least one of a rate of absorption, an amount of storage, and a rate of diffusion of the fragrance. A method of using a porous device includes filling the plurality of pores with fragrance and diffusing the fragrance from an exterior surface.

3D A continuous production process of a dental prosthesis or orthodontic device using a 3D printer and a dental prosthesis or orthodontic device manufactured by the continuous production process

Resumen de: WO2026010233A1

The present invention relates to a dental prosthesis or teeth-straightening device continuous production process using a 3D printer, and to a dental prosthesis or a teeth-straightening device manufactured using the continuous production process. The present invention is for manufacturing a patient-customized dental prosthesis or teeth-straightening device by using 3D data on the oral structure of a patient, wherein a teeth-straightening device is manufactured using 3D printing, supporter separation, washing, post-curing, and heat treatment processes are performed in a continuous process, and the steps proceed by means of a robot without manual handling by a person during proceeding of the steps, thereby improving production efficiency and enabling defective products to be sorted out without additional equipment.

牙颌模型

Resumen de: CN223787727U

本实用新型公开一种牙颌模型，用作热压膜成型制作壳状牙齿矫治器的模具，包括牙颌模型本体，牙颌模型本体的两侧后牙区分别设有向对颌方向延伸的重定位颌元件；重定位颌元件包括分体设置的由第一材料制作的固定部和由第二材料制作的主体部，主体部与固定部以可拆卸方式连接；固定部与牙颌模型本体的一侧表面固定连接，固定部朝向主体部的一侧设置有第一连接部；主体部设置有与第一连接部匹配且沿颊舌向可拆卸安装的第二连接部。

一种股骨颈骨折治疗定位板、制备设备及制备方法

Resumen de: CN121313292A

本发明公开了一种股骨颈骨折治疗定位板、制备设备及制备方法，所述定位板包括主体板和可调式导向模块，所述主体板其形状与股骨近端外侧骨面解剖形态相匹配，并设有至少一个骨钉孔。本发明通过引入与患者解剖形态精准匹配的个体化主体板，并结合多种创新设计的可调式导向模块，有效解决了传统定位板通用性差的问题，能够完美适应不同患者的解剖差异与手术需求；其导向模块所采用的球铰链、偏置滑块‑弧形导轨、弹性变形环及模块化导套等结构，在确保空间角度无级调节功能的同时，显著简化了机械结构，消除了冗余部件，从而实现了高刚性、无间隙锁定，彻底避免了术中微动与移位，极大提升了置钉的精准度和可靠性。

抗感染导管及制作方法

Resumen de: US2025128021A1

Systems and methods for altering the geometry of a fluid channel to prevent upstream mobility of bacteria, using angled obstacles on the interior of the channel that among other things creates vortices that restrict the mobility. An optimized geometry can be realized by an artificial intelligence algorithm or similar methods based on performance of various configurations of obstacle parameters.

用于设计对象的系统和方法

Resumen de: US2024342995A1

Systems and methods for designing additively manufactured objects are provided. In some embodiments, a method includes receiving a treatment plan for a patient's teeth, and determining a set of appliance parameters for a dental appliance configured to implement the treatment plan. The method can also include determining a set of manufacturing parameters for a fabrication system to be used to additively manufacture the dental appliance. The method can further include generating a 3D digital representation of an appliance geometry for the dental appliance. The appliance geometry can be configured to mitigate loss of fidelity at a target region of the dental appliance due to at least one manufacturing parameter of the fabrication system.

用于脊柱畸形手术的4D打印仿生椎板

Resumen de: CN121313964A

本发明公开了用于脊柱畸形手术的4D打印仿生椎板，本发明涉及脊柱畸形手术技术领域，包括：由形状记忆材料制成的椎板主体，所述形状记忆材料为镍钛形状记忆合金。该用于脊柱畸形手术的4D打印仿生椎板，椎板主体通过采用镍钛形状记忆合金制成，其触发温度区间与人体体温高度匹配，手术中可将椎板预制成便于植入的“第一形状”，降低植入操作难度，缩短手术时间；植入体内后，椎板可响应人体温度、体液酸碱度及离子浓度等环境刺激，自动转变为与患者矫正后脊柱生理曲度完全贴合的“第二形状”，实现“植入后自主塑形”；这种形状自适应能力无需医生术中反复调整，避免了器械塑形对椎板力学性能的破坏。

复合生物墨水及其制备方法和基于复合生物墨水构建的骨类器官

Resumen de: CN121313943A

本发明涉及复合生物墨水及其制备方法和基于复合生物墨水构建的骨类器官。所述复合生物墨水为可用于挤出式3D生物打印的复合生物墨水，该复合生物墨水采用甲基丙烯酰化明胶（GelMA）为基质，引入具有M2极化能力的芦荟凝胶以及赋予材料结构稳定性的纳米黏土。本发明提供的复合生物墨水为一种具备内源性免疫调节功能与优异成骨性能的多功能复合生物墨水，其突破了传统依赖短效外源细胞因子的免疫调节方式，以实现对局部免疫微环境的精准调控，促进骨组织的功能性再生，具备更高的生物安全性与临床转化潜力。所述复合生物墨水采用3D挤出式打印成型方法，可以构建出一种具有免疫诱导、生物相容、力学强化与成骨促进等多重功能的复合支架。基于所述复合支架，可以进一步制备得到骨类器官。

一种马鹿角粉支架材料制备装置及其系统

Resumen de: CN121313949A

本发明涉及骨修复材料技术领域，具体涉及一种马鹿角粉支架材料制备装置及其系统，装置包括骨化程度预处理单元、粉碎单元、混合单元、打印单元和调控单元；骨化程度预处理单元包括传输台和控制器，传输台的传输部表面设有定位输送组件，传输台的支架部上设有检测组件和切割组件；制备系统包括：骨化程度预处理模块、气压粉碎模块、配比混合模块、3D打印模块和降解速率调控模块。本发明设计对原料马鹿角进行骨化程度分级预处理对骨松质区域进行精准识别与定向切割，剔除骨密质核心，解决因骨化程度个体差异导致的活性成分波动及孔隙结构不均一问题。

一种半互穿聚合物网络及其制备方法和应用

Resumen de: CN121313915A

本发明涉及血管闭合装置技术领域，具体是一种半互穿聚合物网络及其制备方法和应用。所述半互穿聚合物网络由功能化的聚醚和聚酯共混后，通过光交联制备得到；且具粘附功能基团以及光交联功能基团。本发明将形状记忆分子开关与粘附功能基团通过互穿网络结构设计集成到一种材料中，利用光交联实现材料3D打印和原位交联的协同，提升打印装置的结构稳定性和形状记忆性能，实现了血管闭合装置的智能自部署和稳定粘附封堵。

BIO-PRINTING DEVICE

Resumen de: KR102911103B1

본 발명의 바이오 프린팅 디바이스는, 상단에서 아래로 연장되어 하단에 이어지는 케이스 월 및 상기 케이스 월에 형성된 케이스 중공부를 포함하는, 수송 케이스; 상기 케이스 중공부에 위치하며 상기 케이스 월에 결합되고 서로 이격 배치되는 복수의 가이드 세그먼트; 그리고 상기 케이스 월의 상기 하단에 구비되는 노즐 모듈을 포함하고, 상기 케이스 월은, 상기 수송 케이스의 전면(front face)을 형성하는 전면 케이스 월; 및 상기 수송 케이스의 후면을 형성하는 후면 케이스 월을 포함하고, 상기 복수의 가이드 세그먼트 각각은, 상기 전면 케이스 월에 연결되는 전측 가이드 단부; 상기 후면 케이스 월에 연결되는 후측 가이드 단부; 그리고 상기 전극 가이드 단부에서 뒤로 연장되어 상기 후측 가이드 단부에 이어지는 가이드 바디를 포함할 수 있다.

一种基于金纳米夹层的表面合金微孔化方法及医用植入件

Resumen de: CN121295105A

本发明属于表面处理技术领域，公开了一种基于金纳米夹层的表面合金微孔化方法及医用植入件。所述方法包括：获取原工件；于所述原工件表面沉积一金薄膜以形成一中间工件；将所述中间工件置于等离子真空炉内；其中，加热台、活性屏与顶盖合围形成一空心阴极；所述活性屏及所述顶盖的材质均为靶材，中间工件则置于所述空心阴极内；对等离子真空炉依次抽真空、通入惰性气体后，打开直流脉冲电源进行等离子辉光放电，进而使来自靶材的等离子体对金薄膜进行轰击，并于中间工件表面形成第一合金簇及第二合金簇，第一合金簇与第二合金簇继续互相扩散以于原工件表面形成一具有微孔结构的表面合金层。本发明满足了医用植入件对表面合金化处理的应用需求。

具有多个曲率的弹性密封形成结构

Resumen de: EP4674457A2

The present invention relates to a patient interface for sealed delivery of a flow of air at a continuously positive pressure with respect to ambient air pressure to an entrance to a patient's airways including at least an entrance of a patient's nares. The patient interface is configured to maintain a therapy pressure in a range of about 4 cmH2O to about 30 cmH2O above ambient air pressure in use, throughout a patient's respiratory cycle, while the patient is sleeping, to ameliorate sleep disordered breathing. The patient interface comprises a plenum chamber at least partially forming a cavity pressurisable to a therapeutic pressure of at least 6 cmH2O above ambient air pressure. The plenum chamber includes a plenum chamber inlet port sized and structured to receive the flow of air at the therapeutic pressure for breathing by a patient. The patient interface further comprises a seal-forming structure having a textile membrane constructed and arranged to form a seal with a region of the patient's face surrounding the entrance to the patient's airways inferior to a nasal bridge region of the patient's face. Said textile membrane has at least one hole such that the flow of air at said therapeutic pressure is delivered to at least the entrance to the patient's nares. The seal-forming structure is constructed and arranged to maintain said therapeutic pressure in the cavity throughout the patient's respiratory cycle in use. The textile membrane comprises a first layer constructed

一种增材制造的生物型胫骨托假体及其制作方法

Resumen de: CN121287371A

本发明一种增材制造的生物型胫骨托假体及其制作方法，涉及一种人工膝关节假体技术领域。生物型胫骨托假体包括四种类型：生物型对称胫骨托、生物型对称无柄胫骨托、生物型解剖型胫骨托和生物型解剖型无柄胫骨托。假体主要由托体、多孔结构和堵销等组件构成，通过增材制造技术一体成型，确保精度和强度。多孔结构设计为非规则空间立体网格状，厚度为0.6‑1.6mm，用于促进骨小梁长入，实现生物固定。定位钉采用子弹头形设计，配有排气槽和缺口，简化安装并增强稳定性。制作方法包括设计建模、应力优化、增材制造及后处理步骤，假体采用钛合金材料，满足相关国际标准。本发明具有安装简易、固定可靠、骨长入效果好等优点。

一种用于屈光不正医学研究的小鼠头架构建方法及小鼠头架结构及其安装使用方法

Resumen de: CN121287355A

本发明涉及一种用于屈光不正医学研究的小鼠头架构建方法及小鼠头架结构及其安装使用方法，首先获取小鼠头颈部三维解剖学数据；基于该数据设计头部安装架和眼部实验架的三维模型，并采用增材制造工艺成型。小鼠头架包括头部安装架和眼部实验架，头部安装架设有头部夹孔和颈部套口；眼部实验架设有镜片支架，并连接头部安装架。将头部安装架套接于小鼠头颈部并用绳索固定；将屈光实验镜压入镜片支架中；可在维持头架固定的状态下，拆卸实验镜并通过实验通孔对眼部用药。本发明旨在克服目前的屈光不正实验研究中动物模型造模装置固定方式存在的创伤性大、操作复杂、稳定性差且难以配合眼部用药的技术难题。

基于多重涂覆和UV固化工艺的组织黏附型软骨化双层人工耳廓材料及其制备方法

Nº publicación: CN121288005A 09/01/2026

Solicitante:

浙江省立同德医院（浙江省精神卫生研究院）

Resumen de: CN121288005A

本发明公开了一种基于多重涂覆与UV固化工艺的组织黏附型软骨化双层人工耳廓材料及其制备方法。方法包括：1）采用微流控‑浸渍技术制备负载Kartogenin的甲基丙烯酸化透明质酸（HAMA）微球；2）通过甲基丙烯酰化及羧酰亚胺偶合反应，合成兼具多巴胺功能与光交联能力的双改性HAMA‑DA；3）基于LiDAR与三维重建技术，通过光固化3D打印制备高保真人工耳廓模具；4）配制复合间充质干细胞与载药HAMA微球的甲基丙烯酸化明胶（GelMA）复合浆料；5）在模具表面依次多重涂覆丙三醇层、HAMA‑DA溶液层、GelMA复合浆料层和HAMA‑DA溶液层，过程中配合UV预固化和二次UV固化，制得具备湿态组织黏附性与软骨诱导潜能的双层耳廓结构。该体系为人工耳廓构建提供了先进的材料平台与工艺路径。