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歯冠特徴部を有する歯科インプラント、ならびにこの歯科インプラントを設計および製作するためのシステム、デバイス、および方法

Resumen de: WO2024145635A2

Root-analog dental implants include one or more coronal grooves that are sized, shaped, and/or configured to correspond to a size, shape, and/or position of a bone crest for an extracted tooth a root-analog dental implant is designed and manufactured to replace. The coronal grooves may be configured to engage with bone of an alveolar socket to enhance engagement between the root-analog dental implant and the alveolar socket particularly for the time period following seating the root-analog dental implant within the socket site and prior to osseointegration of the root-analog dental implant with the alveolar socket. This promotes stability of the root-analog dental implant within the socket site immediately following insertion and thereafter, which may decrease movement of the root-analog dental implant within the socket site, decrease a likelihood of foreign material such as bacteria or food entering the socket site, and/or reduce a risk of implant failure and jawbone injury.

用于正畸应用的半结晶含硫聚合物

Resumen de: US2025009476A1

The present disclosure provides polymeric materials comprising semicrystalline sulfur-containing polymers, methods and curable compositions for making the same, and orthodontic appliances made from said polymeric materials.

一种亲骨牙种植体及其制备方法

Resumen de: CN121338088A

本发明涉及牙种植体领域，具体涉及一种亲骨牙种植体及其制备方法，包括以下步骤：步骤1、将亲骨活性生物陶瓷、磷酸锶和β‑甘油磷酸镁混合在钽金属粉末中，获得混合原料；步骤2、将所述混合原料经过3D打印，获得种植体基体；步骤3、在所述种植体基体上生成聚多巴胺涂层，获得涂层种植体；步骤4、将水凝胶粘接在所述涂层种植体上，获得亲骨牙种植体。本发明的聚多巴胺涂层一方面通过邻苯二酚基团与钽金属粉末形成共价键，通过醌基与锶/镁离子螯合。另一方面，聚多巴胺涂层的酚羟基与水凝胶极性基团形成氢键网络，还与水凝胶存在阳离子‑π作用和疏水协同。因此，水凝胶能够通过聚多巴胺涂层与种植体基体间接牢固地粘接在一起。

一种多级孔结构钛基生物活性骨植入复合材料的制备方法

Resumen de: CN121338090A

本发明公开一种多级孔结构钛基生物活性骨植入复合材料的制备方法，属于生物医用材料技术领域。本方法将TC4钛合金粉末、ZrO2粉末、羟基磷灰石粉末及NaCl粉末按一定比例混合后，与多组分粘结剂体系密炼造粒，通过3D打印工艺制备生坯；生坯经温水和草酸催化脱脂后，在氩气保护下进行阶梯式热脱脂和低温预烧结‑高温致密化烧结，制备多级孔结构钛基生物活性骨植入复合材料。本发明制备的复合材料具有独特的三级贯通孔隙结构：由3D打印填充路径间隙产生的毫米级孔隙、NaCl造孔剂水脱去除后遗留的亚毫米级孔隙和HA与基体热膨胀系数差异生成的微米级孔隙，该复合材料力学性能与结构仿生设计均符合人体骨组织的适配性要求。

基于3D打印技术的力度传感刮痧板

Resumen de: CN121337589A

本发明提出基于3D打印技术的力度传感刮痧板，包括以3D打印方式制备的刮痧头，还包括含握持部的刮痧板壳体，刮痧头、握持部之间以燕尾榫结构体、插销连接为可更换刮痧头的分体式结构，所述刮痧板壳体处设有与信息转化模块相连的压力传感器；所述握持部与信息记录模块紧邻；当刮痧头刮痧端对受术用户刮痧施力时，刮痧头的壳体端与压力传感器接触，信息转化模块经压力传感器采集刮痧头壳体端受力数据，并将受力数据送至信息记录模块；本发明采用3D打印成形的刮痧头，并在刮痧头与壳体结合部嵌入压力传感器，实时采集压力数据并通过随机森林回归模型预测最佳舒适度区间，能突破传统刮痧操作的主观性局限。

一种基于FLYZ的3D打印吞咽友好型凝胶及其制备方法

Resumen de: CN121337888A

本发明公开了一种基于FLYZ的3D打印吞咽友好型凝胶及其制备方法，制备方法包括如下步骤：S1、将茯苓、杏仁、陈皮按质量比（2‑5）：1：（2.5‑5）加水进行提取；S2、将食用胶和核桃油分散在步骤S1获得的提取液，并在60‑70℃下搅拌至完全水合，冷却后得到油墨；S3、将步骤S2得到的油墨用3D打印机打印为基于FLYZ的3D打印吞咽友好型凝胶。本发明通过凝胶组分配比与工艺参数控制，获得既具有显著抗氧化活性又满足吞咽困难者（IDDSI 4级/极浓稠—糊状）口感与安全性的3D打印凝胶，实现可重复、可调的硬度、黏附性等质构指标，满足吞咽困难人群对口腔停留与易下咽的要求。

一种双交联3D打印骨修复支架的制备方法

Resumen de: CN121338091A

本申请涉及生物医用材料技术领域，具体公开了一种双交联3D打印骨修复支架的制备方法。该支架由双相磷酸钙基体与明胶甲基丙烯酰化物水凝胶外层复合制成。其制备方法为：首先制备双相磷酸钙墨水，通过3D打印构建多孔支架坯体；接着依次进行氯化钙溶液和戊二醛溶液的双重交联处理，得到力学性能增强的支架基体；然后制备负载经修饰的特立帕肽的明胶甲基丙烯酰化物水凝胶，并将其与支架基体复合，经蓝光交联固化后获得最终产品。本申请的骨修复支架具有良好的生物相容性和成骨活性，可有效促进骨缺损修复。另外，本申请的制备方法工艺可控、重复性好，通过3D打印技术实现了支架结构的精准调控，为个性化骨修复材料的制备提供了新途径。

一种实现聚合物增韧陶瓷基骨支架的增材制造方法

Resumen de: CN121338092A

本发明属于3D打印技术领域，公开了一种实现聚合物增韧陶瓷基骨支架的增材制造方法，采用炭黑油墨作为陶瓷油墨挤出细丝的内芯，打印坯体经干燥及烧结去除炭黑组分，形成具有粗糙内壁的中空的细丝孔，将坯体浸入加热的石蜡中，仅填充挤出细丝的丝间隙而不进入细丝孔，为聚合物填充预留通道，坯体被置于聚合物单体溶液中，聚合物单体通过毛细作用进入细丝孔并固化，以超过石蜡熔点小于聚合物熔点的温度加热坯体去除石蜡，得到聚合物增韧陶瓷基骨支架。有效规避聚合物在热处理过程中的熔化或降解风险，确保细丝孔内聚合物的完整，保障骨支架在生物环境中的力学稳定性与长期增韧效果。聚合物逐渐分解，有利于细胞的生长及新陈代谢的物质运输。

超结构玻璃碳及其制备方法和应用

Resumen de: CN121358688A

一种超结构玻璃碳及其制备方法和应用，首先提供了一种具有各向应力均匀分布的稳定结构的超结构玻璃碳，其次还提供了这种超结构玻璃碳的制备方法、应用，以及基于这种超结构玻璃碳得到的骨修复材料。

STARCH BASED PRINTABLE MATERIALS

Resumen de: US2024226016A1

The instant invention relates to a printable material for Hot Melt Extrusion-based 3D printing (HME-3DP) comprising a pregelatinized cross-linked starch and hydroxypropyl methyl cellulose (HPMC). It also relates to a process for 3D printing using the same. It also relates to products, in particular controlled release solid dosage forms, obtained thereof by 3D printing.

NEW CUTOUT FOR ELASTIC ALIGNERS, METHOD OF MANUFACTURING SAME AND SYSTEM FOR ORTHODONTIC TREATMENT

Resumen de: WO2026013591A1

This patent description outlines the comprehensive details of the improved elastic cutout in orthodontic aligners, comprising a polymeric material formed with multiple cavities configured to apply a load to at least one tooth to cause movement of said tooth. The integrated cutout for elastics is positioned on the aligner, wherein cutout for elastics is configured to retain an elastic band and wherein cutout for elastics is configured to be connected with the button arranged on the opposite aligner. The cutout for elastic is integrated into aligner and cutting of the cutout for elastic is performed on bubble-like element. This invention also provides a method for manufacturing of the cutout for elastics and the orthodontic treatment system which comprises the aligner with incorporated cutout for elastics, the opposite aligner on which a secure lock-up mechanism is fixed and elastic band which specifically is designed to create an elastic connection between the secure locking mechanism and the cutout for elastics.

Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods

Resumen de: US20260015438A1

The present disclosure provides a photopolymerizable composition. The photopolymerizable composition includes a) 40-60 parts by weight of a monofunctional (meth)acrylate monomer, per 100 parts of the total photopolymerizable composition; b) a photoinitiator; and c) a polymerization reaction product of components. A cured homopolymer of the monofunctional (meth)acrylate monomer has a glass transition temperature of 125 degrees Celsius or greater. The polymerization reaction product of components includes i) a diisocyanate; ii) a hydroxy functional methacrylate; iii) a polycarbonate diol; and iv) a catalyst. The polymerization reaction product includes a polyurethane methacrylate polymer. Often, the polycarbonate diol has a number average molecular weight of greater than 1,000 grams per mole (g/mol) or a weighted average of all polycarbonate diols present in the components has a Mn of greater than 1,000 g/mol; alternatively, the polyurethane methacrylate polymer has a weight average molecular weight of 8,000 g/mol or greater. An article is also provided including the photopolymerizable composition reaction product. Further, the present disclosure provides articles and methods of making articles. Methods are additionally provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an article; and generating, with the manufacturing device by an additive manufacturing process, the article based on the digital o

CELL-LADEN BIOINK CIRCULATION-ASSISTED INKJET-BASED BIOPRINTING TO MITIGATE CELL SEDIMENTATION AND AGGREGATION

Resumen de: US20260014799A1

A system for active circulation of bioink in inkjet bioprinting, comprises a bioink reservoir, an inlet connected to a pump, an outlet from the pump to the bioink reservoir, wherein the pump circulates bioink from the inlet to the outlet.

FIBRIN GEL SHEET FOR CELL TRANSPLANTATION

Resumen de: US20260014297A1

An object of the present invention is to provide a fibrin gel sheet for cell transplantation that has an unprecedented larger size while cells are uniformly dispersed and embedded, and a method for producing the same. The present invention provides a fibrin gel sheet for cell transplantation, wherein cells are uniformly dispersed and embedded in the fibrin gel sheet, and the fibrin gel sheet has a size of 2.25 cm2 or larger in terms of a surface area of one surface and has a thickness of 1 mm or smaller, and a method for producing the same.

METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR THREE-DIMENSIONAL PRINTING OF MODULAR HETEROGENEOUS DENSITY DEVICES FOR RANGE MODULATION IN PARTICLE THERAPY

Resumen de: US20260014393A1

A method for generating a range modulating device for radiotherapy includes obtaining a medical image of a patient. The method further includes determining, using the medical image, a design of a range modulating device having non-uniform density for radiotherapy for the patient. The method further includes 3D printing, using the design, the range modulating device by continuously varying the ratio of filament to air in each voxel of a plurality of voxels. The method can also include performing radiotherapy on the patient by inserting the range modulating device in a beam path between a beam from a radiation source and the patient.

PERSONALIZED MEDICAL DEVICE AND METHOD OF ITS PREPARATION

Resumen de: US20260013991A1

A personalized medical device intended for correction of defects, in particular in the orofacial area is multicomposite and comprises a hard tissue replacement and a soft tissue replacement. The hard tissue replacement is a hard core of biocompatible thermoplastic material and the soft tissue replacement is a biocompatible elastic substance. Preparation of personalized medical device even in the prenatal period using CT, MRI and 3D/4D electronic USG imaging and “additive manufacturing” technology.

Nasal Device For Improving Nasal Breathing

Resumen de: US20260014014A1

A nasal device may include a standard shaped to extend over an exterior portion of a user's nose from a first nasal opening, across flexible nasal tissues, to a second nasal opening. The standard may have a first end and a second end. A first regulator may be connected to the first end and extend therefrom into the first nasal opening. The first regulator may be shaped to engage the flexible tissues and regulate their position by pushing them toward an underside of the standard. A second regulator may be connected to the second end and extend therefrom into the second nasal opening. The second regulator may also be shaped to engage the flexible tissues and regulate their position by pushing them toward the underside of the standard.

BIOMIMETIC IMPLANTS

Resumen de: US20260013994A1

Implantable devices for spinal cord and peripheral nerve injury are described. The implants include a three-dimensional printed structure having stem cells disposed therein. Also disclosed are methods of treating neuronal injuries with the disclosed implants.

Emergency Cardiac And Electrocardiogram Electrode Placement System

Resumen de: US20260013770A1

An emergency cardiac and electrocardiogram (ECG) electrode placement device is disclosed herein. The emergency cardiac and electrocardiogram (ECG) electrode placement device incorporates electrical conducting materials and elastic material into a pad that is applied to a chest wall of a patient, which places multiple electrodes in the appropriate anatomic locations on the patient to quickly obtain an ECG in a pre-hospital setting.

A COMPOSITE STRUCTURE AND RELATED METHODS THEREOF

Resumen de: WO2026015085A1

There is provided a composite structure for promoting wound healing, the structure comprising, a compressible substrate; and a bioactive material disposed on said compressible substrate, wherein the bioactive material comprises a mixture of a synthetic homopolymer and a bioactive copolymer.

MANDIBULAR DISTRACTOR APPARATUS AND METHODS

Resumen de: WO2026015744A1

Disclosed herein is a lingual mandibular distractor and methods and systems for designing the same. The lingual mandibular distractor as disclosed herein is configured to be installed at a lingual surface of the mouth of a patient. The lingual mandibular distractor as disclosed herein is designed based on the intended patient's specific anatomy. 3D printing processes may be utilized to create the frame of the lingual mandibular distractor, and an expansion assembly is connected to the frame to complete the lingual mandibular distractor appliance.

METHOD FOR MANUFACTURING SURGICAL HEMOSTATIC CLIP AND SURGICAL HEMOSTATIC CLIP MANUFACTURED THEREBY

Resumen de: WO2026014565A1

Disclosed is a method for manufacturing a surgical hemostatic clip. The method for manufacturing a surgical hemostatic clip comprises: a 3D printing step of producing, through a 3D printing process, a surgical hemostatic clip including a pair of legs that are arranged to face each other so as to form an overall U-shape and have a polygonal cross-sectional shape, and a plurality of vascular pressing projections protruding from mutually facing inner surfaces of the pair of legs; a burr-removal step of removing burrs adhering to the edges or surfaces of the pair of legs and the plurality of vascular pressing projections; a heat-treatment step of heat-treating the deburred surgical hemostatic clip at a temperature of 500°C to 1000°C for 24 hours or more; and a surface-treatment step of heating the entire surface of the surgical hemostatic clip (100) to 450°C or higher by using an oxygen-propane flame to form a titanium oxide TiO2 layer, subsequently polishing the surface of the surgical hemostatic clip using at least one of Al2O3, V2O5, and SiO2 powders, and then polishing the surface of the surgical hemostatic clip using 50,000-mesh diamond powder.

NOVEL COMPOSITE TOOLS FOR REINFORCING DENTAL HAND-SCULPTED AND 3D-PRINTED COMPOSITES

Resumen de: WO2026013683A1

The present invention provides novel tools and methods for improving load transfer in dental isotropic particulate reinforced composites. By creating textured composite interfaces during chairside composite lamination or layering, the load transfer in hand sculpted and 3D printed composites can be significantly enhanced without the need for embedding fibers or reinforcing elements. This leads to improved stress transfer, load-bearing capacity, and reduced shrinkage stress in dental composites. The invention also has applications in structural composite materials technology, aerospace engineering, and resin SLA 3D printing, allowing the mechanical properties and response of the composite to be easily enhanced or tailored.

Devices and methods for stent graft extraction

Resumen de: AU2025279692A1

22293675_1 (GHMatters) P121726.AU.1 A device for extracting an endovascular stent graft from a vessel, comprising a ring having a first open end and a second open end; and a sidewall extending away from the ring at the second open end; wherein: the sidewall is curved along a length of the device; the sidewall extends partially around a circumference of the second open end of the ring, such that the sidewall defines an open 5 portion; a thickness of the ring at the first open end is greater than the thickness at the second open end; and the ring and the sidewall are rigid. ec e c

A CUSTOMIZED ACETABULAR CAGE WITH INTEGRATED AUGMENT

Nº publicación: AU2024269527A1 15/01/2026

Solicitante:

JAJAL KETAN
JAJAL, Ketan

Resumen de: AU2024269527A1

The present invention relates to a customized acetabular cage. More particularly, the present invention relates to a hip or acetabular cage which has integrated with it the bone augment required for a particular hip arthroplasty surgery. The augment is integrated into the acetabular cage in a seamless manner. The present hip cage is further provided with flanges having minimum dimensions which reduce the requirement for incision. The seamlessly integrated bone augment reduces the overall size of the implant and also ensures a perfect fit.