Absstract of: US2025090103A1
Conditions of pathophysiologic dysglycemia, associated with type 1 diabetes, can be detected early, including in children. Glycemia data is collected by continuous glucose monitoring devices connected to a cloud server. The server learns person-specific patterns of glycemia and trains a model accordingly, which may serve as a baseline for comparison or as the basis for prediction of future patterns. Such models are conditioned by risk factors and various concurrent activities such as exercise and consumption of sugars. Person-specific models trained at different time periods give different simulated patterns of glycemia. Deviations between the simulated patterns, or between the predicted and actual patterns, can indicate progression of pathophysiologic dysglycemia and type 1 diabetes. These models and comparisons can be further interpreted by the software to result in a reported recommendation for additional diagnostic testing or a reported conclusion of diagnosis and recommendation of preventative intervention.
Absstract of: AU2025201387A1
A system, a method, and a computer program product for providing wearable continuous blood glucose monitoring. In some embodiments, there is provided a method that includes receiving, at a smartwatch, an alert representative of a glucose state of a host-patient coupled to a glucose sensor; detecting, at the smartwatch, a predetermined action indicative of a request to generate a glance view providing an indication of the glucose state of the host-patient; and presenting, at the smartwatch and in response to the detecting, the glance view providing the indication of the glucose state of the host-patient.
Absstract of: US2025095869A1
Presented herein is a handheld analyte measurement device. The analyte measurement device includes one or more software applications to help the user manager their diabetes. Embodiments and descriptions of the various applications are provided below in conjunction with the handheld analyte measurement device.
Absstract of: US2025095862A1
In some examples, an apparatus, such as a mobile phone can include an input module such as a touch screen, a camera, a processor, and computer readable medium. The camera captures one or more images of a person. The processor can use a single machine learning model to estimate the human body features of the person based on the captured images, and use the human body features to generate a disease risk assessment value associated with diabetes and cardiovascular disease risks. The human body features can include at least one or more of: 3D body shape, or body shape indicators; and one or more of: blood flow, blood pressure, heart rate, respiratory rate, heart rate variability, cardiac workload, irregular heartbeats, or stress index. The machine learning model can be trained over a set of training images.
Absstract of: WO2025055788A1
An OCTA-based non-invasive continuous blood glucose measurement method and apparatus. The OCTA-based non-invasive continuous blood glucose measurement method comprises: performing continuous OCT scanning imaging on a target tissue region, then using a depth attenuation characteristic of an OCT signal to extract a three-dimensional scattering coefficient of the target tissue region, and generating a three-dimensional microvascular distribution of the target tissue region; then accurately distinguishing a blood scattering coefficient and a tissue scattering coefficient on the basis of the three-dimensional scattering coefficient and the three-dimensional microvascular distribution; using an electrochemical method to measure reference blood glucose concentrations at two moments, and finally, respectively combining the reference blood glucose concentrations with the blood scattering coefficient and the tissue scattering coefficient to achieve continuous measurement of a blood glucose concentration and an interstitial fluid glucose concentration. According to the method, on the basis of OCTA guidance, the synchronous measurement of the interstitial fluid glucose concentration is implemented while accurate measurement of the blood glucose concentration is implemented, and the method has a great heuristic significance for the optical non-invasive blood glucose measurement.
Absstract of: WO2025055545A1
The present application provides an eardrum temperature measuring apparatus, a blood sugar measuring method, a system, and a device. By means of a high-precision eardrum temperature measuring apparatus measuring multiple temperature points disposed in the ear canal, a target eardrum temperature is estimated without contacting the eardrum; next, based on the target eardrum temperature, a target oral temperature is estimated on the basis of a pre-established correspondence relationship between eardrum and oral cavity temperatures; then, by means of a pre-calibrated invasive blood sugar value and an oral calibration temperature, a temperature correspondence relationship between a blood sugar increment and an oral temperature increment is established, and a target blood sugar increment can be calculated; finally, based on the target blood sugar increment and the pre-calibrated invasive blood sugar value, a target blood sugar value is calculated, that is, by means of the precision measuring apparatus and the conversion relationships between multiple pieces of precision data, the accuracy and stability of blood sugar measurement are improved, the influence of external factors on blood sugar measurement is reduced, and the ability of a measurement process to resist interference is improved.
Absstract of: WO2025055546A1
The present application provides a tympanic membrane temperature measuring apparatus, a blood glucose measuring method, a system, and a device. First, a target tympanic membrane temperature is acquired; a target oral cavity temperature is estimated on the basis of a pre-established temperature correspondence between the tympanic membrane and the oral cavity; a temperature correspondence between blood glucose increments and oral cavity temperature increments is then established on the basis of a pre-calibrated invasive blood glucose value and an oral cavity calibration temperature, so as to calculate a target blood glucose increment; and finally, a target blood glucose value is calculated on the basis of the target blood glucose increment and the pre-calibrated invasive blood glucose value. In this way, impact of other factors on blood glucose measurement is reduced while increasing the apparent temperature in the blood glucose measurement process.
Absstract of: US2025090053A1
The present invention relates to a body attachment unit for continuous blood glucose monitoring, in which a body attachment unit is manufactured so as to be assembled in an applicator, thereby minimizing additional work and allowing attachment of the body attachment unit to a body simply by operation of the applicator. In particular, a wireless communication chip is provided in the body attachment unit to enable communication with an external terminal, thereby enabling simple and convenient use without additional work of connecting a separate transmitter, and allowing easier maintenance. In addition, activation occurs by a user's operation after the body attachment unit is attached to the body, such that an activation start time can be adjusted to a time appropriate to the user's needs, and activation occurs in a stabilized state, thereby allowing more accurate blood glucose monitoring.
Absstract of: US2025090052A1
An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
Absstract of: US2025090082A1
There is a need for more effective and efficient predictive data analysis, such as more effective and efficient data analysis solutions for performing predictive monitoring of the glucose-insulin endocrine metabolic regulatory system.
Absstract of: US2025090754A1
Embodiments can relate to an insulin delivery controller which implements a processor configuration to efficiently attain an insulin delivery target. The insulin delivery controller can include a processor and a memory associated with the processor. The processor can process glucose data received from the memory, including a data representation of glycemic disturbance (d(t)). The processor can determine a glucose rate of change (G′(t)). The processor can generate a command signal to dynamically reshape a glycemic disturbance within a prediction horizon of the insulin delivery controller according to the G′(t). The processor can generate an insulin command signal for an insulin delivery unit to adjust an insulin delivery dosage amount and/or an insulin delivery dosage rate.
Absstract of: US2025090753A1
Disclosed herein are techniques related to making trend based adjustments to insulin dosage. In some embodiments, the techniques may involve obtaining, based on glucose measurements performed on a person, a glucose value and a glucose rate of change (ROC). An initial insulin amount to deliver to the person is calculated based on this glucose value. However, an adjustment value can be obtained in response to a determination that the glucose value exceeds a glucose threshold, and that the glucose ROC exceeds an ROC threshold. The adjustment value represents an adjustment to be applied to the initial insulin amount when the glucose threshold and the ROC threshold are both exceeded. The adjustment value can be predetermined, based on earlier glucose measurements performed on the person. For instance, the adjustment value and the thresholds can be jointly determined through a computer simulation using a person-specific physiological model.
Absstract of: US2025090758A1
A botulinum toxin syringe having a barrel has volumetric marking graduations scaled at four units per 0.1 mL. These volumetric marking graduations allow for ease of unit conversion and can reduce the likelihood of overdosing or under dosing of botulinum toxin. The syringe may further comprise further volumetric marking graduations configured to be interchangeably used for administration of insulin or botulinum toxin. The syringe may further comprise further volumetric marking graduations configured for interchangeably use for administration of different types of botulinum toxin.
Absstract of: US2025094109A1
A continuous glucose monitor for wirelessly transmitting data relating to glucose value to a plurality of displays is disclosed, as well as systems and methods for limiting the number of display devices that can connect to a continuous glucose transmitter. In addition, security, including hashing techniques and a changing application key, can be used to provide secure communications between the continuous glucose transmitter and the displays. Also provided is a continuous glucose monitor and techniques for authenticating multiple displays, providing secure data transmissions to multiple displays, and coordinating the interaction of commands and data updates between multiple displays.
Absstract of: EP4523621A2
A method for providing blood glucose data is provided. In response to a suspension of a continuous basal insulin delivery, by an insulin delivery pump, the method identifies a condition indicating continuing hypoglycemia that continues when basal insulin delivery is suspended; and performs an action, by the insulin delivery pump, based on identifying the condition.
Nº publicación: US12251242B1 18/03/2025
Applicant:
UPDOC INC [US]
UpDoc Inc
Absstract of: US12251242B1
An artificially intelligent, voice-based method for prescribing, managing and administering at least one medication for management of type 2 diabetes to a patient. Aspects of the present disclosure provide for a system and method for configuring one or more clinical algorithms according to one or more clinical protocols to configure a conversational AI model. The conversational AI model is configured to drive a conversational AI agent configured to facilitate a plurality of multi-turn conversational interactions between a patient user and the conversational agent to enable automated initiation and titration of one or more diabetes medications for the patient.