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一种高强抗菌医用钽铜合金复合材料的制备方法

Absstract of: CN122974942A

本发明属于金属增材制造及医疗器械技术领域，具体涉及一种高强抗菌医用钽铜合金复合材料的制备方法。按质量百分比称取94%～96%的球形纯钽粉末和4%～6%的球形铜源粉末，通过声学共振混合后在氩气氛围中真空干燥；将混合粉末铺置于增材制造舱体中，预热基板，先在成形件底部采用低激光功率打印过渡层，再采用高激光功率打印成形件本体，成形舱内氧含量控制在100ppm以下；打印完成后经分离、清洗得到高强抗菌医用钽铜合金植入器械。本发明通过精准控制铜含量（4～6wt.%）实现≥99.99%抗菌率与优异细胞相容性的平衡，通过过渡层和基板预热解决了高熔点钽铜合金打印翘曲问题，压缩强度≥1400MPa，应变≥50%，适用于打印各类骨科、口腔科等植入医疗器械。

一种嵌入-体积复合3D打印方法

Absstract of: CN122973696A

本发明公开了一种嵌入‑体积复合3D打印方法，以海藻酸钠‑明胶复配体系构建热力学稳定的双水相支撑浴，以光交联生物墨水为挤出相，先通过嵌入式挤出在双水相支撑浴内精准沉积出内部异质结构，再向完成嵌入式打印的双水相支撑浴体系中加入光引发剂并混匀，采用可见光进行三维光场投影固化，使所述双水相支撑浴形成外部基体相，同时将内部异质结构封装于外部基体相内，单次流程便可实现多材料、多细胞异质结构一体化成型；100s以内便可完成整体固化，细胞存活率大于80%，可有效解决现有技术难以兼顾高效率、高生物相容性与多材料异质成型的难题。

激光调控改善TC4合金细胞粘附性的方法及TC4合金

Absstract of: CN122974937A

本发明公开了激光调控改善TC4合金细胞粘附性的方法及TC4合金，涉及增材制造材料工艺技术领域；该方法包括如下步骤：分别以激光功率、激光扫描速度、激光扫描间距为单因素变量设置多个不同的激光加工参数组；采用激光粉末床熔融增材制造技术制备TC4钛合金成型件；筛选出具有未熔融孔隙、烧蚀孔隙和致密三种不同孔隙类型的样品；对筛选出的样品进行细胞粘附性实验，获得具有细胞粘附性能的TC4钛合金。本发明通过主动引入烧蚀孔隙，在保证力学性能满足骨植入体要求的同时，大幅降低弹性模量，显著改善细胞粘附性能，有效避免应力屏蔽现象，适用于骨植入体等医疗器械领域。

动物来源的组织脱细胞化方法及包含动物来源脱细胞化组织的生物墨水

Absstract of: WO2025141426A1

A method of decellularization of animal tissue, comprising the steps of: mechanical homogenization of animal-derived tissue, incubation of the homogenized tissue from step a) in a solution of trypsin and EDTA, subjecting the filtered tissue to incubation in a PBS buffer solution with a pH in the range of 7.2-7.6 containing a non-ionic detergent at a concentration of 4 - 2% and NH4OH at a concentration of 0.2 - 0.08%, rinsing the tissue with a PBS buffer solution containing an antimicrobial agent, incubation in a deoxyribonuclease solution at a concentration of 0.001 to 0.003% (w/v), rinsing the decellularized tissues obtained with a PBS buffer solution containing an antimicrobial agent, wherein the non-ionic detergent is a compound with a molecular weight of 596 g/mol and additional steps of incubating the tissue in the solution PBS buffer with a pH of 7.2- 7.6 containing a non-ionic detergent at a concentration of 1.5-0.5% and NH4OH ata concentration of 0.2-0.08%, where the incubation is carried out at a temperature below room temperature for 36-48h, and incubation of the tissue in a PBS buffer solution with a pH of 7.2-7.6 containing a non- ionic detergent at a concentration of 0.75-0.25% and NH4OH at a concentration of 0.2-0.08%, where the incubation is carried out at a temperature below room temperature for 36-48h. Bioink containing decellularized tissue of animal origin.

一种内窥镜三信号一体化隔离传输系统

Absstract of: CN122994457A

本发明公开了一种内窥镜三信号一体化隔离传输系统，包括主机信号集成单元、隔离耦合单元、手柄总线和手柄信号分离单元；主机信号集成单元将控制信号嵌入图像数据流形成串行融合数据流，隔离耦合单元对串行融合数据流和直流电源分别进行电气隔离后，通过融合网络将两者耦合至同一组差分线对构成的手柄总线，手柄信号分离单元从手柄总线上分离出电源和信号并恢复控制信号与图像数据。由此将电源、数据和控制三类信号融合于一组差分线传输，减少线芯数量，在满足电气隔离要求下改善线缆柔细度与操作手感。

基于虚拟现实和眼动追踪的谵妄筛查和干预系统

Absstract of: CN122973021A

0001 本发明提供一种基于虚拟现实和眼动追踪的谵妄筛查和干预系统，结合沉浸式VR交互终端、头部姿态补偿的双目眼动采集技术、多维度谵妄特异性测试任务、多子模型融合的分级筛查算法、转化风险预测模型，实现ICU谵妄的非侵入式、客观化、精准化早期筛查与风险预警，同时配套个性化VR干预方案，形成全流程闭环管理，彻底解决现有临床谵妄评估的主观依赖性强、ICU场景适配性差、早期预警能力不足的核心问题。

低算力穿戴设备的离线式身体精力评分方法及系统

Absstract of: CN122991624A

本发明涉及可穿戴设备技术领域，更具体地，涉及低算力穿戴设备的离线式身体精力评分方法及系统。该方案包括以每日凌晨4:00为固定结算时刻，采集前日00:00至当日03:59的生理数据作为原始输入数据集；基于睡眠参数计算分项求和并扣减清醒时长扣分，钳位得睡眠得分；按累计有效晨起天数N分级调用固定基线、全量平均或30天滑动平均生成HRV与静息心率个人基线，映射输出对应得分；按前一日中高强度心率累计分钟数查表得运动得分；五项得分按0.4、0.3、0.15、0.1、0.05加权求和后，串行执行熬夜扣减与生理期缩放修正，取整钳位输出0~100分评分与五档状态等级，全程单次结算，功耗低，适于低算力设备。

一种表面肌电信号识别方法、模型训练方法及系统

Absstract of: CN122986342A

0001 本发明提供一种表面肌电信号识别方法、模型训练方法及系统，该方法包括：通过包含多个二维时频谱图的训练样本集对初始表面肌电信号识别模型进行训练，局部调整提取模块进行局部时频特征提取并通过特征序列重构模块转换和空间位置编码模块叠加空间偏置，输入时空上下文建模模块输出全局时空融合特征序列，最终通过多任务并行输出模块输出动作类别预测值、关节状态预测值和肌肉疲劳指数预测值，与标签的偏差构建融合损失函数对初始表面肌电信号识别模型进行参数更新获得表面肌电信号识别模型；能够实现表面肌电信号识别的稳定性和准确性并实时反馈肌肉状态。

一种PICC穿刺智能导引装置及使用方法

Absstract of: CN122973101A

本发明公开了一种PICC穿刺智能导引装置及使用方法，属于医疗器械领域。该装置为可拆卸外挂附件，装配于超声探头，用于PICC改良Seldinger穿刺。装置通过血管深度自动测量模块自动采集皮肤至靶血管垂直深度H，并采集五项患者个体化特征参数，微控制器依据θ0=arctan(H/D)计算基准角度，并通过预训练的AI修正模型修正后，再经临床安全区间限幅输出目标穿刺角度，供操作人员手动调节或自动驱动导针座摆角锁止。当基准角度超出临床安全区间时，装置执行钳位输出并给出提示。本发明实现自动测深‑几何模型基准运算‑AI个体化修正‑双重角度钳位‑角度输出的完整智能闭环，相比纯几何基准角度方案，提高了穿刺成功率。

手指外骨骼阻抗辨识与牵伸力度闭环控制方法及系统

Absstract of: CN122973234A

本发明公开手指外骨骼阻抗辨识与牵伸力度闭环控制方法及系统，属于生理参数测量与分析技术领域，用于手指外骨骼阻抗辨识与牵伸力度闭环控制，包括步采集电机电流、多通道肌电和温度信号并预处理，获得关节角度与净阻抗力矩，基于肌电归一化计算主动收缩指数并筛选有效样本，扣除神经性力矩得到机械性挛缩阻抗力矩；构建三参数模型辨识关节刚度及弹性区终点，引入温度与瘢痕因子修正安全上限；依据接近度变量实现力位混合控制，保持期辨识松弛参数并允许角度递增，三级熔断分级响应，记录每日牵伸剂量与最大角度并同步至治疗师端。本发明通过多模态生理信号融合辨识关节阻抗特性，实现个性化安全牵伸调控，提高评估准确性与治疗有效性。

基于操作日志的作业人员疲劳状态评估方法及终端设备

Absstract of: CN122991607A

0001 本发明公开一种基于操作日志的作业人员疲劳状态评估方法及终端设备。本方法获取交易处理时长与商品总难度系数计算实际单位难度耗时，经标准耗时模型得到预测单位难度耗时，二者差值生成耗时残差；采集连续残差构建残差序列，提取残差均值、残差变异系数、正残差占比、残差偏度；对特征归一化后加权融合得到综合疲劳系数，依据分级阈值判定疲劳等级。所述终端设备包括存储器、处理器，处理器运行程序可实现上述评估方法。本方案使用收银终端原生交易日志，无需额外采集硬件，消除客流量、商品复杂度的业务负载干扰，依靠多维度特征量化疲劳，规避硬件成本、隐私泄露问题，减少业务波动造成的评估误判，实现无侵入、高精度的作业人员疲劳实时评估。

一种用于脓毒症相关疾病诊断和治疗的分子标志物组合及其用途

Absstract of: CN122979436A

0001 本发明属于生物医药领域，具体涉及一种用于脓毒症相关疾病诊断和治疗的分子标志物组合及其用途。所述分子标志物组合包括 PLA2G4A 、 FLOT1 、 NEU1 、 MSH5 、 AGER 、 CCHCR1 、 APOM 、 CLIC1 、 HLA‑DRA 、 NOTCH4 、 PPT2 、 PDIK1L 和 ABHD16A 中的一种或一种以上，其为脓毒症治疗和疾病管理领域提供了新的方向。

基于磁导航与直视成像的术后消化道管路智能引导系统

Absstract of: CN122973767A

0001 本发明提供基于磁导航与直视成像的术后消化道管路智能引导系统，涉及术后消化道管路置入技术领域。该基于磁导航与直视成像的术后消化道管路智能引导系统，包括集成一体化磁可视复合导管导丝、可置入消化道的多功能导管本体、磁导航定位模块、直视成像采集模块、双模态信息融合处理单元以及人机交互终端；所述磁导航定位模块由一体化封装于复合导丝尖端内腔的永磁标记单元与布置于患者体外的分布式磁场传感阵列组成，用于实时解算导管尖端在三维空间内的坐标与姿态参数。通过融合磁导航定位与直视成像双模态技术，实现无辐射床旁精准定位、腔内可视化监测、分级安全预警与智能路径引导，提升置管成功率与安全性，适配各类术后消化道置管场景。

COMPUTER-IMPLEMENTED METHOD AND CAD SYSTEM FOR AUTOMATICALLY CENTERING AND ALIGNING A 3D MESH SCAN OF A SINGLE JAW IN A CAD SYSTEM

Absstract of: EP4553764A1

The subject application provides a computer-implemented method (100) and CAD system (200) for automatically centering and aligning a 3D mesh scan (10) of a jaw in a CAD system.The inventors propose to automatically center and align a 3D mesh scan (10) of a jaw in a CAD system, wherein the initial orientation of the 3D mesh scan (10) is arbitrary.

METHOD AND SYSTEM FOR DIAGNOSING DRY EYE SYNDROME USING ARTIFICIAL INTELLIGENCE MODEL

Absstract of: KR103037941B1

본 발명의 인공지능 모델을 이용한 안구건조증 진단 방법은, 사용자의 안구 이미지를 획득하는 단계, 안구 이미지를 구성하는 각 픽셀의 파장별 반사율 데이터를 예측함으로써, 하이퍼스펙트럼 영상을 생성하는 단계, 하이퍼스펙트럼 영상의 파장별 반사 데이터에 기초하여, 사용자의 안구 구조 별 상태 데이터를 생성하는 단계 및 인공지능 모델에 안구 구조 별 상태 데이터를 입력하여, 사용자의 안구 건조증을 진단하는 단계를 포함함으로써, RGB 안구 이미지로부터 생성된 하이퍼스펙트럼 영상과 인공지능 분석을 기반으로, 비침습적이고 정량적인 안구건조증 진단을 가능하게 한다.

着用可能な聴診デバイス

Absstract of: WO2022040456A1

Provided herein are systems, devices, and methods to measure auditory signals from a subject to determine a state of a subject. The auditory signals measured may provide a tool to monitor the development of disease state(s) or abnormal physiologic conditions (e.g., wheezing, fluid accumulation, abnormal heart murmur or rhythm, etc).

用于确定优化的乳房压迫的系统和方法

Absstract of: US20260325089A1

According to one aspect of an exemplary embodiment of the disclosure, an imaging device or system, e.g., a mammography imaging system or device, includes an optimized compression module on the imaging system to provide optimized compression of a breast on the mammography imaging system employing information from one or more sensing device(s) disposed on the mammography imaging system. Examples of the types of sensing devices include force sensors, ultrasound sensing devices, MEMS radar devices and/or time-of-flight (ToF) sensing devices. The information provided by the sensing devices is compared with an optimized compression stop point determined by the optimized compression module for use in controlling movement of various components of the imaging system, e.g., a compression plate, to compress the breast to an optimized position to enhance the quality of images to be obtained of the breast and/or maximizing patient comfort.

流量传感器系统

Absstract of: WO2025231022A1

A system may include a flow sensor and/or a base. The flow sensor may include a sensor to detect a property of a medical device received by the system. The base may be configured to receive the flow sensor. The base may include a stabilizing surface; a monitoring surface rotatable at least 90 degrees relative to the stabilizing surface, the monitoring surface including a reflective portion; and a sensor mount rotatable at least 90 degrees relative to the monitoring surface and including: means to secure the flow sensor to the sensor mount; and a sensor channel adapted provide a field of detection for the sensor through the sensor mount toward the reflective portion.

単一パッケージ自動薬物送達システム

Absstract of: WO2023168284A1

Disclosed herein is a combination of an automated insulin delivery system and a continuous glucose monitor integrated into a single, wearable package. The system may use any combination of delivery methods and detection methods, wherein the delivery methods include a cannula, a microneedle array, and a transdermal patch, and wherein the detection methods include electrochemical methods, opto-fluorescent methods, and spectrographic methods.

一种血糖管理系统

Absstract of: CN120825675A

The invention discloses a blood glucose management system which is characterized in that when a patient operates and establishes communication connection, at least one of a detection module, an infusion module and a program module serves as signal source equipment to send low-power broadcast signals, and at least one of the equipment serves as equipment to be paired and establish communication connection; a patient operates the to-be-paired communication connection establishment device to approach the signal source device, when the to-be-paired communication connection establishment device enters the effective range of the broadcast signal, the broadcast signal can be searched, and the to-be-paired communication connection establishment device is paired with the signal source device to establish communication connection; the range is generally smaller than the conventional distance between the two devices, the situation that wrong communication connection is established due to the fact that the to-be-paired communication connection establishing device searches wrong broadcast signals can be avoided, a patient can automatically establish communication connection with the signal source device without inputting a device code, time and labor are saved, and the patient experience is improved. And the use experience of the patient is improved.

医療用情報処理システム、医療用情報処理方法、及びプログラム

Absstract of: WO2023145503A1

This technology relates to a medical information processing system, medical information processing method, and program that make it possible for a user to recognize the reliability of additional information, which is provided using three dimensional information on the interior of a patient's body generated by SLAM, etc. Three dimensional information for the patient including a three dimensional map of the surgical field is generated, the reliability of the three dimensional information is assessed, and on the basis of said reliability, the presentation form of the additional information, which is provided using the three dimensional information, is modified.

呼吸治疗系统的声学分析

Absstract of: US20220339383A1

0001 Method and apparatus obtain information about a patient and/or a respiratory therapy system that is configured to deliver respiratory therapy to the patient. The respiratory therapy system may include a flow generator configured to generate a supply of pressurized air along an air circuit to a patient interface. A sound signal representing a sound in the air circuit may be processed to obtain cepstrum data. A time series of delay estimates based on acoustic signatures of the cepstrum data may be generated. Each acoustic signature may represent a reflection of sound from a patient interface along the air circuit. Variation in the time series of delay estimates may be analysed. One or more output indicators based on the variation may be generated. The one or more output indicators may concern patient and/or system status.

動作改善提案装置、動作改善提案方法、動作改善提案管理プログラム、および動作改善提案システム

Absstract of: JP2026171564A

0001 【課題】ユーザの動作を改善させるための提案を行うこと。 【解決手段】動作改善提案装置であって、ユーザが所定動作を行っている間の動作関連情報を取得する動作関連情報取得部と、前記所定動作を改善させるための身体的健康ケア提案を選定する選定部と、選定された前記身体的健康ケア提案を所定通知先へ通知する通知制御部と、を備え、前記選定部は、取得した前記動作関連情報を用いて、前記身体的健康ケア提案を選定する。 【選択図】図２

用于评估和/或调节神经病症的可穿戴设备、系统和方法

Absstract of: CN122954384A

0001 提供了一种用于评估和/或调节受试者的神经病症的可穿戴设备，所述可穿戴设备包括头戴设备框架、EEG模块和tDCS模块，当头戴设备框架配戴在受试者的头部上时，EEG电极被定位在受试者的第一区附近或与之接触，并且tDCS电极被定位到受试者的第二区或与之接触。本文描述了其他示例实施例。在一些实施例中，所述可穿戴设备具有紧凑、便携式且简单的设计，并且其大小和形状被设定为适应受试者头部的不同大小和形状，同时EEG电极和tDCS电极可以准确且高效地瞄准受试者的期望目标区。

一种可低温塑形多孔负压引流材料的制备洗脱与使用方法

Nº publicación: CN122956742A 23/10/2026

Applicant:

日照铭志医疗科技有限公司济宁医学院

Absstract of: CN122956742A

本发明涉及生物医用增材制造专用材料、生物医用材料制造技术领域，具体公开了一种可低温塑形多孔负压引流材料的制备、洗脱与使用方法。负压引流材料以生物相容性高分子基材为核心，通过增材制造技术结合低温塑形改性工艺制备，材料内部形成相互连通的多级多孔结构，且在2‑15℃低温环境下具备可塑型性，能匹配各类复杂形态创面的贴合需求；同时设计专属的梯度洗脱工艺，实现材料成型后残留助剂的高效去除，保证生物安全性。本发明还明确了材料的临床使用规范，包括低温塑形操作、创面贴合、负压连接及更换流程。