Absstract of: US20260341444A1
A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.
Absstract of: WO2021192880A1
The present invention further reduces the time required to dispense medicine. A conveyance device (70) conveys a medicine accommodation part (1) from a storage position (10), at which are stored a plurality of medicine accommodation parts (1) that each accommodate medicine, to a delivery position (30), at which the medicine accommodated in the medicine accommodation part (1) is extracted from the medicine accommodation part (1), and returns the medicine accommodation part (1), from which was extracted some of the accommodated medicine, to the storage position (10) from the delivery position (30). A standby position (20), at which the medicine accommodation parts (1) conveyed from the storage position (10) and toward the delivery position (30) are caused to wait, is provided between the storage position (10) and the delivery position (30). A medicine accommodation part (1) that accommodates medicine, which is determined to not be for use in the next medicine preparation, is returned to the storage position (10) from the standby position (20). A medicine accommodation part (1) that accommodates medicine, which is determined to be for use in the next medicine preparation, is caused to wait at the standby position (20) until the next medicine preparation without being returned to the storage position (10).
Absstract of: WO2026226212A1
A wearable device for non-invasive monitoring of intracranial pressure includes a wearable structure configured to be secured to a head of a user; an ultrasound transducer positioned to align with an eye of the user when worn; a motorized control mechanism that dynamically adjusts a position and angulation of the ultrasound transducer; a fluid management system that maintains an acoustic coupling between the ultrasound transducer and the eye of the user; an integrated air vent system to regulate pressure, prevent condensation, and maintain imaging quality within the wearable structure; and a processor coupled to the ultrasound transducer. The processor is to employ a reinforcement learning-based control system for optimizing transducer placement; acquire ultrasound images of an optic nerve sheath; analyze the ultrasound images to measure an optic nerve sheath diameter (ONSD); and determine a likelihood of elevated intracranial pressure based on the measured ONSD.
Absstract of: AU2025257886A1
Apparatuses, systems, and methods for autonomously-initiated analyte measurements and/or calculation of analyte concentrations based on the analyte measurements. An apparatus (e.g., an analyte sensor or a sensing device of the analyte sensor) may be configured to take and sets of sensor measurements at a first frequency having a period equal to a threshold number of cycles of the clock. The stored sets of sensor measurements may include first sets of sensor measurements at the first frequency and second sets of sensor measurements at a second frequency, and the first frequency is greater than the second frequency. Another apparatus (e.g., a transceiver, display device, and/or data management system) may be configured to receive sets of sensor measurements conveyed by the analyte sensor, calculate time stamps for the sets of sensor measurements, and calculate analyte concentrations based on the sets of sensor measurements and the calculated time stamps.
Absstract of: AU2025258407A1
Described herein are methods of assessing the risk of dementia in a subject using an odor-based test, or "smell test". These methods can be self-administered by the subject under the instruction of a computing device via a user interface. Methods of administering a smell test as described herein can optionally be combined with measuring and quantifying the level of at least one biomarker for dementia (e.g., CXCL10, CCL2, IL-6) in a biological sample collected from the subject. Also provided are methods to treat dementia (e.g., dementia associated with Alzheimer's disease, dementia associated with a subset of Alzheimer's disease patients with TDP-43 pathology).
Absstract of: AU2026253875A1
27106278_1 (GHMatters) P127225.AU.1 A method includes detecting a beginning of a donation process; in response to detecting the beginning of the donation process, providing an output; determining an amount of time remaining for the donation process; in response to detecting the amount of time remaining for the donation process, updating the output; detecting a loss in pressure; in response to detecting the loss in 5 pressure, updating the output; detecting an ending of the donation process; and in response to detecting the ending of the donation process, updating the output. The donation process may include a plasma donation using an apheresis machine. The detecting the beginning of the donation process may include detecting a flow of fluid. The output may include one or more of a light and a sound. The output may be provided on a side of an apheresis machine. 10 ct c t
Absstract of: US20260335333A1
0000 Disclosed is a method of treating traumatic encephalopathy syndrome (TES) in a patient in need thereof by administering a therapeutically effective amount of a rho-kinase inhibitor. In one embodiment, the rho-kinase inhibitor is fasudil.
Absstract of: US20260335519A1
0000 The described technology generally includes systems and processes for a PD optimization process may operate to estimate, predict, or otherwise determine the value of PD dose variables values based on patient characteristics and/or PD prescription information. In one embodiment, a PD optimization process may be or may include a UFV determination process, operative to determine a predicted UFV for a patient. In some embodiments, the UFV determination process may include training a computational model to generate a predicted UFV output based on input of patient characteristics, PD prescription information, PD outcomes (for instance, UFV), and/or historical information associated with patient characteristics, PD prescription information, and/or PD outcomes. In some embodiments, a feedback control process with continuous Intraperitoneal Pressure (IPP) and hydration status measurements may be used to keep the hydration status of the patient within a target level ran. Other embodiments are described.
Absstract of: US20260335046A1
Apparatuses and methods for customized retainers to prevent relapse. In particular, described herein are customized retainers, and methods and apparatuses for making customized retainers that specifically reenforce and prevent movement of one or more teeth having a higher likelihood of relapse following completion of an orthodontic treatment plan.
Absstract of: US20260341513A1
The present disclosure provides a method of facilitating a health assessment. Further, the method may include receiving a medical inquiry. Further, the medical inquiry may be generated by a user. Further, the method may include analyzing the medical inquiry. Further, the method may include generating an assessment query based on the analyzing. Further, the generation of the assessment query may be based on one or more of a template and a first machine learning model. Further, the template includes a standardized assessment query. Further, the method may include transmitting the assessment query. Further, the method may include receiving a response from the healthcare communication infrastructure. Further, the response corresponds. Further, the method may include analyzing the response. Further, the method may include determining a diagnosis data based on the analyzing. Further, the method may include transmitting the diagnosis data.
Absstract of: US20260337551A1
It is provided a cell macroencapsulation device for implanting cells in a recipient comprising cells encapsulated in a porous membrane, wherein the porous membrane consists of a sugar network coated with a polymeric solution comprising porogen, which can be used as a graft to transplant islets while protecting the graft from the immune system as well as providing enhanced convection and diffusion to ensure long-term cell survival and physiological insulin delivery.
Absstract of: US20260335674A1
Systems and methods are provided for modelling and fabricating a patient-specific immobilization support. Image data is obtained for characterizing an exposed surface of a body portion and a support structure employed to support the body portion during imaging. The image data is processed to determine a position and orientation of the support structure based on spatial features of the support structure, and surface data associated with the exposed surface of the body portion is segmented from the image data. The segmented surface data and the position and orientation of the support structure are employed to generate a digital model of a patient-specific immobilization structure that is attachable to the support structure for immobilizing the body portion between the patient-specific immobilization structure and the support structure. Prior to fabricating the patient-specific immobilization structure, an initial digital model may be modified, optionally according to beam parameters associated with a treatment plan.
Absstract of: US20260341401A1
0000 Disclosed are systems comprising an analyzing unit comprising a) a receiver configured to receive a plurality of sequencing reads from a sample, the plurality of sequencing reads comprising at least one genetic variation undetectable within a sequencing system error rate; b) a noise processing filter configured to: i) reduce signal noise from the plurality of sequencing reads; ii) calculate a confidence indication based on a determination from at least one sequencing read of the plurality of sequencing reads; and iii) calculate a corrected confidence indication based on a comparison of the determinations from at least two sequencing reads, each drawn from the plurality of sequencing reads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Absstract of: US20260336889A1
0000 A lockable container encoding system and method is disclosed. The lockable container encoding system is for use in the manufacture of encodable lockable containers, wherein the encodable lockable container comprises an annular sidewall having a plurality of annular rings, the annular rings having an inner and outer surface, the inner surface featuring a plurality of selectable removable tabs for the encoding of lockable containers. The lockable container encoding system includes a tumbler for receiving unencoded encodable lockable containers, a receptor having a sidewall dimensioned and configured to hold a plurality of encodable lockable containers, a first articulating arm comprising a plurality of ring manipulators, a vision system in communication with the ring manipulators to monitor the physical position of the plurality of annular rings of the encodable lockable container, and a second articulating arm comprising a plunger having a shearing blade; wherein the shearing blade comprises guide rails couplable to the shearing blade, wherein the shearing blade removes a plurality of selected removable tabs from an unencoded lockable container to encode the container.
Absstract of: WO2026223214A1
The present application relates to a cardiopulmonary resuscitation compression control apparatus, a computing device, and a computer-readable storage medium, belonging to the field of medical instruments. The apparatus comprises: a determination module, used for determining an expected hemodynamic parameter of a target organism according to a plurality of actual hemodynamic parameters of the target organism acquired by a blood flow monitoring apparatus; an acquisition module, used for acquiring a current compression parameter of an external chest compression apparatus; and an updating module, used for updating the next compression parameter of the external chest compression apparatus according to the compression parameter, the expected hemodynamic parameter, and the actual hemodynamic parameters. The technical solutions of the embodiments of the present application can achieve high-quality external chest compression.
Absstract of: WO2025099487A1
Aspects of the disclosure include microfluidic print heads for bioprinting core/shell fibers having consistent diameters and shell thicknesses, and methods of making high-density tissue fibers comprising cell populations of therapeutic interest for implantation, as well as the high-density tissue fibers produced thereby.
Absstract of: US20260337578A1
Provided herein compositions and methods including bioprinted tissue fibers comprising precisely patterned cancerous and non-cancerous cells that are capable of recapitulating a desired tumor microenvironment in vitro. The subject tissue models enable the automated high throughput screening of anti-cancer therapies in a biologically-relevant human system, and can be further personalized with patient-specific cells.
Absstract of: DE102025139221A1
Die vorliegende Erfindung betrifft eine Modellplatte (14, 15) für Artikulatoren (1), welche ausgebildet ist, einen Teil eines Kiefermodells (16, 17) mit dem Artikulator (1) feststehend und zerstörungsfrei lösbar zu verbinden, mit einer Mehrzahl von Stegen (14b, 15b), welche eine Mehrzahl von Öffnungen (14c, 15c) bilden, wobei die Modellplatte (14, 15) mittels einer badbasierten Photopolymerisation hergestellt ist. Die Modellplatte (14, 15) ist dadurch gekennzeichnet, dass zumindest einige der Öffnungen (14c, 15c), vorzugsweise alle Öffnungen (14c, 15c), durch Verbindungskanäle (14d, 15d) miteinander und/oder durch Verbindungskanäle (14d, 15d) mit der Umgebung der Modellplatte (14, 15) verbunden sind.
Absstract of: US20260341481A1
The present invention relates to guidance in spatial setups of a room in a medical facility. In order to provide improvements for a facilitated work procedure in medical interventions, a device (10) for guidance in spatial setups of a room in a medical facility is provided that comprises a data input (12), a data processor (14) and an output interface (16). The data input is configured to provide procedure data (18) about a current executed medical procedure. The data input is also configured to provide spatial data (20) of at least one of the group of staff and equipment relating to the currently executed medical procedure. The data processor is configured to calculate upcoming physical movement of at least one of the group of the staff and the equipment based on the procedure data and the spatial data procedure data. The data processor is also configured to determine, based on the calculated upcoming physical movement, at least one of the group of equipment movement instructions (22) and staff spatial guidance (24). Further, the output interface is configured to provide at least one of the group of the equipment movement instructions and the staff spatial guidance.
Absstract of: US20260341455A1
0000 Disclosed is an injection device for injecting of a dose of a medicament, the injection device including a housing having a body detachably connectable to a container part configured to accommodate a medicament container, a drive mechanism arranged in the body and operable to expel the dose of the medicament from the medicament container, a first antenna disposed on or in a first portion of the body and configured for wireless signal transmission with an electronic container identifier provided on or in the container part, a second antenna disposed on or in a second portion of the body electrically connected to the first antenna and configured for wireless signal transmission with a transceiver of an electronic module of an add-on device connectable to the injection device, and an electronic device identifier configured for wireless signal transmission with the transceiver.
Absstract of: US20260341070A1
An evaluation device includes: a memory that stores three-dimensional data of a shape of a foot of a subject measured by a measurement device; and a processor that computes an index value specifying the shape of the foot from the three-dimensional data read from the memory. The processor computes, from the three-dimensional data, at least one index value among an index value related to a frontal plane of the foot, an index value related to a sagittal plane of the foot, and an index value related to a horizontal plane of the foot. The processor evaluates a flat-foot level of the foot of the subject based on the computed index value.
Absstract of: US2015190312A1
0001 Provided is a medicine dispensing apparatus including a plurality of medicine cassettes for respectively dispensing desired types of medicines. The medicine dispensing apparatus allocates medicine information on a medicine to be dispensed to one of the medicine cassettes when the medicine information is given. Then, the medicine dispensing apparatus drives the medicine cassette according to a predetermined driving condition corresponding to the medicine information allocated to the medicine cassette to dispense the medicine from the medicine cassette. By using the medicine dispensing apparatus, it is possible to reduce a user work for dispensing the desired types of medicines.
Absstract of: US20260341507A1
0000 In order to solve the problem that it is difficult to acquire information on a future status of a user, an information processing apparatus 100 includes a biological information acquiring unit 143 that acquires time series information on a status of a living body based on measurement results of a biological signal of a user; a prediction information acquiring unit 145 that acquires prediction information on future time-series information on the user, using learning information configured using time-series information acquired from measurement results of a biological signal in the past, and the time-series information, and a future information output unit 147 that outputs future information on a future status of the user based on the prediction information. Accordingly it is possible to acquire information on a future status of a user.
Absstract of: US20260341522A1
Since it is useful if information on a status of a living body of a user can be utilized, an information processing apparatus 100 includes: a storage unit 110 in which information is stored; a biological information acquiring unit 143 that acquires measurement information on a status of a living body of a providing user; a content generating unit 161 that generates content information using the measurement information; and a content accumulating unit 163 that accumulates the content information generated by the content generating unit 161, in the storage unit 110, in association with a provider identifier with which the providing user can be identified. Accordingly, it is possible to generate content information from information on a status of a living body of a providing user, and to utilize the information on the status of the living body of the user.
Nº publicación: US20260336220A1 29/10/2026
Applicant:
ALIGN TECH INC [US]
Align Technology, Inc.
Absstract of: US20260336220A1
Methods and systems for designing dental appliances are provided. In some embodiments, a method includes: receiving a digital representation of an appliance geometry for a dental appliance configured to be worn on a patient's teeth; predicting a change in a size of a portion of the dental appliance when the dental appliance is fabricated via an additive manufacturing process; adjusting the appliance geometry of the dental appliance to compensate for the predicted change in size; and generating instructions for fabricating the dental appliance based on the adjusted appliance geometry.