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83
results.
Updated on
13/11/2026 [07:40:00]
Results 25 to 50 of 83
Absstract of: CN123037692A
本申请提供一种高密度扩散光学断层成像方法及系统，属于光学成像技术领域。该方法包括：基于目标受试者的立体头部模型，确定目标受试者的头部几何信息，并根据头部几何信息，打印生成适用于目标受试者的采集帽，采集帽上包括多个近红外光探头；通过采集帽上的多个近红外光探头对目标受试者的待测脑区进行扫描，以采集待测脑区的时间分辨光信号；基于时间分辨光信号进行图像重建，以生成并显示目标受试者的高分辨率脑图像。本申请可以达到提高信号采集效率和空间分辨率，降低设备使用难度，并统一重建图像流程，以提高成像稳定性和可靠性的效果。
Absstract of: WO2020104873A1
In one embodiment, an orthodontic article is described comprising the reaction product of a polymerizable composition comprising: a) 30-70 parts by weight of monofunctional (meth)acrylate monomer, wherein a cured homopolymer of at least one monofunctional (meth)acrylate monomer has a Tg of at least 30, 35, 40, 45, 50, 55, or 60°C; and b) urethane (meth)acrylate polymer comprising polymerized units of an aliphatic polyester diol. Also described are polymerizable compositions, as well as methods and systems for making an article utilizing 3D printing.
Absstract of: CN123038342A
本发明公开了一种微孔3D打印聚乳酸支架的制备方法，所述的方法有两步：第一步是通过无机盐颗粒加入聚乳酸的有机溶液中搅拌得到含有无机盐颗粒聚乳酸原液；第二步是将聚乳酸原液经过3D打印在水相刻蚀溶液中进行模板溶出法，由此实现具有微孔的3D打印聚乳酸支架。该发明通过改变无机盐颗粒、有机溶剂以及水相刻蚀溶液，提供了一种实现聚乳酸材料物理致孔的方法。被认为是一种绿色可控、潜力巨大的聚乳酸材料致孔方法。
Absstract of: WO2025093948A1
Certain embodiments disclosed herein provide an ophthalmic surgical system. The system includes a fluidics module and a controller. The fluidic module includes a surgical cassette bay and one or more indicator lights. The one or more indicator lights correspond to one or more fluidic ports on the fluidics module. The controller includes a memory including executable instructions and a processor. The processor is in data communication with the memory. The processor is configured to execute the instructions to cause the system to: determine that a surgical cassette is coupled to the surgical cassette bay; determine a type of the surgical cassette; illuminate at least one of the one or more indicator lights based on the determined type of the surgical cassette; and extinguish the at least one of the one or more indicator lights upon receiving an input indicating that a fluidic tubing is fluidically coupled with the corresponding fluidic port.
Absstract of: US20250066525A1
0000 The present disclosure provides methods, systems, devices, and kits for creating composite materials from a single resin, the composite materials having multiple continuous phases. The disclosure includes a process to three-dimensionally print objects (e.g., orthodontic appliances) with composite properties. In some aspects, the composite properties are formed from a single formulation with components that, when processed, have hard and soft continuous phases. In some aspects, the composite properties are formed by separately processing the hard phase components and the soft phase components. In some aspects, the composite materials and devices are three-dimensionally printed using the processed material.
Absstract of: US20250099338A1
0000 A drug sorting apparatus with reduced packaging time is provided. A drug sorting apparatus includes: a second accommodating portion in which a plurality of sorting cups are arrangeable, the plurality of sorting cups being configured to accommodate a plurality of types of drugs in a state of being sorted by type; a packaging mechanism configured to package a drug, which is accommodated in the accommodating portion; a first dispensing mechanism configured to dispense, for each of the plurality of sorting containers, the drug accommodated in the accommodating portion to the packaging unit; and a container takeout mechanism configured to take out a sorting container from the accommodating portion so as to deliver the sorting container to the first dispensing mechanism, wherein the first dispensing mechanism is configured to tilt the sorting container received from the container takeout mechanism, to thereby dispense the drug accommodated in the sorting container to the packaging unit.
Absstract of: CN123038344A
本发明公开了一种微气泡增强型复合脂质体、3D打印墨水及制备方法，涉及生物医用材料与微创增材制造技术领域；复合脂质体包括脂质双分子层、包裹在脂质双分子层内的微气泡和交联剂；脂质双分子层为磷脂酰胆碱、胆固醇、PEG化脂质的任意组合；复合脂质体采用微流控芯片连续流制备，通过复合脂质体制备3D打印墨水；本发明将微气泡封装于脂质体内部，利用微气泡气体核心在超声场中的声空化效应产生的局部机械应力，直接驱动脂质双分子层的瞬时孔道形成和交联剂释放，消除了热损伤风险；解决了3D打印生物墨水固化成型安全稳定性差、成型精度不足的问题。
Absstract of: US20260345015A1
0000 Systems, devices, and methods described herein enable generation of images and other visual elements for assisting a clinician in evaluating one or more physiological conditions, including, for example, cardio-respiratory conditions of a patient. In some embodiments, a composite image is generated that includes a visual image of a target portion of a user's body, such as the neck, which is overlaid with visual elements indicative of a patient's physiological information. Images of the target portion are obtained using a sensing device positionable on the patient in a pre-determined position and orientation via a positioning element that uniquely fits with a patient anatomical feature. The images are processed to extract spatially resolved signals within multiple subregions. The signals are processed using synchronizing data spanning multiple physiological cycles to identify waveform segments, which are processed to generate a visual indication representative of the waveform segments, which is rendered in the composite image.
Absstract of: US20260345032A1
A gait monitoring system includes first and second monitoring devices respectively associated with first and second feet of a user and positioned within footwear. Each monitoring device includes at least one inertial sensor, a processor, memory, a timing circuit, and a wireless communication architecture, and is configured to acquire inertial data during an activity. The monitoring devices operate independently during the activity and store time-associated data locally. Inertial data is converted to stride data at the monitoring devices and transferred to a computing device and associated based on relative timing using correlation parameters to align first-foot and second-foot data. The system determines step events, phase-based gait metrics including stance and swing phases, and bilateral gait characteristics based on the associated data. Derived metrics are compared to a baseline gait profile and used to determine cumulative impact and deviations from typical gait behavior.
Absstract of: US20260345265A1
0000 A perioperative cobotic system is provided for executing surgeon-specific workflows in an operating room environment. The system includes a configurable cobotic platform with one or more articulated robotic arms, tool handling interfaces, and surgical-environment sensors. A workflow engine retrieves and applies personalized surgeon profiles defining instrument preferences, procedural sequencing, ergonomic positioning, and timing cues, based on surgeon identification. An instrument handling module positions tools and configures the cobot in accordance with the selected profile. An adaptive learning engine refines workflow profiles using intraoperative data and surgeon feedback over time. Integration with electronic medical records and scheduling systems enables procedure- and patient-specific profile adjustments. A context-aware execution module responds to voice, gesture, or footswitch inputs and detected surgical phases. Safety, override, and logging features support compliant operation and performance analytics.
Absstract of: WO2026231126A1
A computer-implemented method (100) for radiotherapy treatment planning. The method comprises: receiving (102) an indication of a first RTP task; selecting (104), from a plurality of RTP model combinations, one or more first RTP model combinations for performing the first RTP task; and outputting (106) the one or more first RTP model combinations. Each of the plurality of RTP model combinations has a commissioning status and comprises a plurality of RTP model components of different RTP model component types. The one or more first RTP model combinations are selected based on the commissioning statuses of the one or more first RTP model combinations.
Absstract of: US20260351401A1
Processing of medical system requests, including voice requests, are described. For example, a recording is received that includes a voice request captured by a medical system during a medical procedure, and audio content of the recording is transcribed to text. A response to the voice request is generated by: determining, based on the text, to invoke a tool from a plurality of tools, the tool having a function associated with the voice request; responsive to a call to the tool, receiving a result generated from an execution of the function by the tool based on inputs provided as part of the call, the inputs including at least a portion of the text; and generating the response to the voice request based on the text and the result. The response is provided to the medical system for presentation on a display of the medical system.
Absstract of: WO2026231127A1
Certain aspects of the disclosure provide systems and methods for verification of updates to remote medical devices. For example, methods may include obtaining an update to an operational parameter of a medical device, outputting a first code, and obtaining a second code based on the first code and the update to the operational parameter. Based on verification of the second code, the operational parameter may be updated.
Absstract of: WO2026231500A1
This invention provides a device for detecting a fracture in a limb bone in a patient's limb. A first strap and a second strap are each adapted to adjustably engage each of a first location and a second location on the limb that correspond to opposing ends of the limb bone. A sound transmitter and receiver, located, respectively, on each of the first strap and the second strap, closely engage a respective limb location adjacent to the limb bone so as to transmit and receive modulated sound signals therethrough. The first strap and the second strap allow the sound transmitter and sound receiver to be applied to mirrored locations on a limb having the fractured limb bone and an opposing limb bone that is unfractured. A comparison process, in a processor, compares modulated sound signals received with respect to the unfractured limb bone to those of the fractured limb bone.
Absstract of: WO2026232139A1
A method can be provided for real-time intraoperative neuromonitoring (IONM) of a patient during a surgical procedure, wherein the method includes: (a) monitoring mean arterial pressure (MAP), heart rate (HR), and motor evoked potential (MEP) sweeps from a plurality of monitored muscle channels of the patient; (b) constructing a multi-channel waveform data matrix from baseline MEP sweeps; (c) generating a PCA-projected representation of the baseline MEP sweeps by applying principle component analysis (PCA) to the multi-channel waveform data matrix; (d) producing a primary RF model, by applying a configurable weighting modifier to a random forest (RF) classifier formed based on the PCA-projected representation of the baseline MEP sweep; (e) forming a secondary RF model based on (i) output from the primary RF model, (ii) the real-time MAP, and (iii) the real-time HR; and (f) determining based on the secondary RF model at least one of a rolling classification accuracy metric, and (ii) a composite monitoring change probability score.
Absstract of: WO2026231461A1
Embodiments of the disclosure are directed to a framework that may be used for designing, developing, and implementing one or more wellbeing skills. The disclosed Reframe framework provides a tool for designing wellbeing skill development programs for a desired skill. These skills can be used by a person desiring to improve their wellbeing or by a person having problems with a wellbeing related issue and desiring to improve a skill or capability. Non-limiting examples of such problems include stress, anxiety, burnout, or relationship issues.
Absstract of: WO2026231638A2
Disclosed herein are method and systems for identifying a patient having a risk of having limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC) based on determining a LATE-NC risk score from MRI imaging.
Absstract of: WO2026231056A1
A polymer blend including the following precursors: 10 wt.% to 95.0 wt.% of a hydrophilic polymer; 5.0 wt.% to 95.0 wt.% of a hydrophobic polymer; and 0.1 wt.% to 5 wt.% of an initiator. A method for preparing said polymer blend, comprising: mixing the hydrophilic polymer, the hydrophobic polymer, and the initiator via solution processing, melt processing, or a combination thereof, to form said polymer blend. Said polymer blend is cured under UV irradiation or thermal treatment to yield an amphiphilic elastomer. Said amphiphilic elastomer is swollen to obtain a hydrogel.
Absstract of: US20260345114A1
A system for sweep trajectory simulation, wherein the system includes at least a processor and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to receive a plurality of 3D imaging data, generate, using the plurality of 3D imaging data, ultrasound simulation data, wherein the ultrasound simulation data includes ultrasound data and probe position data, generate, using the ultrasound simulation data, a plurality of 3D models, and train, using reinforcement learning algorithms, a sweep trajectory simulation model. In an embodiment, the sweep trajectory simulation model is trained using 3D imaging data, the probe position data, and the plurality of 3D models and the sweep trajectory simulation model is configured to output a time-step vector relating to the movement of a catheter.
Absstract of: WO2026229231A1
A method for obtaining three-dimensional x-ray images (108) of a sample (102), comprising the steps: a) arranging (S1) a sample (102) in an object plane (130) of an x-ray imaging system (100), the sample (102) having a first size (A1) in the object plane (130), b) obtaining (S2) two-dimensional x-ray images (106) of a region of interest (104) of the sample (102) including information for different projection angles (α), the region of interest (104) having a second size (A2) in the object plane (130) of at least 0.01 times the first size (A1), and c) reconstructing (S5), computer-implemented, a three-dimensional x-ray image (108) of the region of interest (104) based on the obtained two-dimensional x-ray images (106).
Absstract of: WO2026227145A1
A wearable system and method for monitoring and guiding rehabilitation exercises is disclosed, particularly for knee physiotherapy. The system includes a wearable sensor module (comprising an inertial measurement unit, range-of-motion sensor, onboard processor, and wireless transceiver) and a companion software application on an external device. The sensor module computes joint-angle trajectories and exercise-performance metrics in real time, transmitting data to the software application, which provides immediate visual and/or auditory feedback to guide correct movement. The system records exercise repetitions with time-stamped adherence data and updates configuration settings based on user performance trends. Additional features include a magnetometer for enhanced accuracy, adaptive filtering algorithms, and an LED array for direct visual feedback. The method enables unsupervised physiotherapy by comparing real-time metrics to target trajectories and issuing corrective prompts. A gamified application tracks progress, shares metrics with accountability partners, and integrates with electronic health records, enhancing adherence and recovery outcomes.
Absstract of: WO2026231792A1
A system for craniofacial developmental assessment and intervention planning includes a processor; and a memory coupled to the processor, the memory having instructions stored thereon which when executed by the processor, cause the system to: access a plurality of photographs associated with a patient; generate an oral image model based on the plurality of photographs; determine a level of deviation of the oral image model using a reference feature distribution; determine a craniofacial developmental assessment based on the level of deviation of the oral image model; and output an intervention plan correlated to the craniofacial developmental assessment.
Absstract of: WO2026231061A1
This invention is designed for orthopedic applications. It features a proximal surface (1) for tibial articulation, a distal surface (2) for calcaneal engagement, and a central canal (4) for a fixation nail. Offered in spherical (7), ellipsoidal (8), and anatomically contoured (9) shapes, the prosthesis includes a gyroid lattice structure for improved osseointegration. A method for its creation involves 3D modeling from CT scans, shape design, lattice definition, and 3D printing, focusing on dimensions and density variations to ensure proper fit and functionality while addressing anatomical needs.
Absstract of: US20260345302A1
0000 A 3-D model for a patient after resection of a portion of a maxilla or mandible may include a physical representation of a remainder of facial bones after resection of the portion of the maxilla or mandible of the patient, a fixation implant formed to define a reconstruction of the portion of the maxilla or mandible that is aligned with the remainder of the facial bones, a plurality of instances of a dental implant abutment operably coupled to the fixation implant, and an imaging reference aide overlaying and operably coupling to the plurality of instances of the dental implant abutment to provide one or more reference points for imaging. The fixation implant may be removably operably coupled with the 3-D model and may include harvested segments of fibula to recreate the portion of the maxilla or mandible. The imaging reference aide may be separate from the fixation implant.
Nº publicación: US20260345385A1 05/11/2026
Applicant:
THE REGENTS OF THE UNIV OF CALIFORNIA [US]
The Regents of the University of California
Absstract of: US20260345385A1
0000 Retinal transplantation holds potential for vision restoration in severe retinal degeneration, but manual delivery of retinal sheets often suffers from imprecision and tissue damage due to unstable instruments. To address this, researchers developed a 3D-printed, motorized retinal sheet injector controlled via Arduino and a foot pedal with three preset actuator positions. In comparative tests with four participants, motion analysis showed that the manual injector caused nearly three times more tip movement variance than the motorized version (p<10<−11>). Although tip velocities were generally lower with the motorized injector, the differences were not statistically significant. In placement accuracy trials using gelatin models, the motorized system significantly outperformed the manual one (~52% vs. ~37% accuracy, p=0.00999), with complete misplacements occurring only in the manual group.
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