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81
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Updated on
16/07/2025 [07:26:00]
Results 75 to 81 of 81
Absstract of: AU2023262222A1
The invention relates to a gelled reaction medium for the detection, identification, enumeration and/or isolation of at least one target microorganism in a sample that may contain same, comprising at least one binding partner specific to a component of a target microorganism or of a component derived from said microorganism, coupled to at least one nanoparticle to form at least one binding conjugate.
Absstract of: CN119842745A
本发明公开了鼠伤寒沙门菌毒力基因Ict的鉴定及其减毒疫苗候选株的制备与应用。本发明选择强毒力鼠伤寒沙门菌SL1344株作为亲本株，将其中降解代谢衣康酸的关键毒力基因Ict进行敲除，构建鼠伤寒沙门菌SL1344减毒疫苗候选株。通过小鼠动物毒力实验、免疫保护力实验和安全性实验等证实该疫苗候选株SL1344‑ΔIct缺失株，不仅对动物的致病力显著降低，且提供了良好的免疫原性和免疫保护力。本发明实现对强毒力鼠伤寒沙门氏菌株的减毒，可广泛应用于沙门菌的防控，为研制沙门菌的减毒活疫苗及活载体疫苗奠定基础。
Absstract of: CN119855897A
The present invention provides a method for producing a recombinant bacterium, which is characterized in that the recombinant bacterium is used for producing a recombinant bacterium, and the recombinant bacterium is obtained by using a recombinant bacterium, which is preserved in the Deersche Sammlarg von Mikroorgani sung Zel lkulturen and has been preserved in the Deersche Sammlarg von Mikroorgani sung Zel lkulturen with a preservation number of DSM 32786. The present invention relates to a method for resisting Salmonella typhimurium infection by using a culture of Lactobacillus rhamnosus LRH10 having a preservation number of DSMZ GmbH, Lactobacillus paracasei LPC12 having a preservation number of DSMZ GmbH, Lactobacillus fermentum LF26 having a preservation number of DSMZ GmbH, Streptococcus thermophilus ST30 having a preservation number of DSMZ 32788, and Lactobacillus helveticus LH43 having a preservation number of DSMZ 32787, and more specifically, to a method for resisting Salmonella typhimurium infection by using a culture of Lactobacillus rhamnosus LRH10 having a preservation number of DSMZ GmbH.
Absstract of: CN119842544A
The invention belongs to the field of microorganisms, and relates to lactobacillus rhamnosus and application thereof. The lactobacillus rhamnosus KC3 is separated from Xinjiang healthy bactrian camel milk, and the lactobacillus rhamnosus KC3 has the activity of inhibiting various pathogenic bacteria such as escherichia coli, klebsiella pneumoniae, salmonella, proteus mirabilis, staphylococcus aureus, staphylococcus epidermidis, listeria monocytogenes and streptococcus agalactiae. The metabiotics of the strain can enhance the sensitivity of pathogenic bacteria such as escherichia coli and staphylococcus aureus to antibiotics such as beta-lactam antibiotics, and can synergistically enhance the antibacterial effect of the beta-lactam antibiotics to the pathogenic bacteria such as escherichia coli, staphylococcus aureus, CRE or MRSA. The lactobacillus rhamnosus KC3 metagen can also destroy cell walls of pathogenic bacteria such as escherichia coli, staphylococcus epidermidis, CRE or MRSA and the like, and the formation of bacterial biofilms is inhibited.
Absstract of: CN119846199A
The invention relates to the technical field of analysis and detection, in particular to an immunochromatography test strip for detecting shiga toxin-producing escherichia coli O103. Based on the characteristics of the quantum dots and the fluorescent microspheres, a probe is synthesized by utilizing the purified protein expressed by the pET-28a-O103 strain and the fluorescent microspheres, and the immunochromatography rapid detection test strip for identifying the shiga toxin-producing escherichia coli O103, which is simple to operate, is established, can be used for rapidly identifying the shiga toxin-producing escherichia coli O103 clinically, and can be used for rapidly detecting the shiga toxin-producing escherichia coli O103. The method has important significance on prevention and control of Escherichia coli diseases.
Nº publicación: WO2025080776A2 17/04/2025
Applicant:
CHILDRENS MEDICAL CT CORP [US]
THE CHILDREN'S MEDICAL CENTER CORPORATION
Absstract of: WO2025080776A2
Aspects of the invention described herein relate to a vaccine composition comprising at an antigenic polysaccharide and an immunomodulatory amount of a sialic acid binding moiety, wherein the sialic acid binding moiety comprises sialic acid binding domain (SBD) which is not fused to an antigenic polypeptide.
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