Alerta

INFORMATION PROCESSING DEVICE, SELECTION ASSISTANCE METHOD, AND SELECTION ASSISTANCE PROGRAM

Absstract of: WO2026069850A1

To improve the manner in which oral care products are presented, an information processing device (1) comprises an acquisition unit (101) that acquires explanatory text that indicates the state of the oral cavity of a subject, an inference unit (103) that inputs a prompt that has been generated on the basis of the acquired explanatory text and instructs inference of an oral care product that is suited to the state of the oral cavity of the subject from among prescribed candidates into a language model (3) to cause output of inference results, and a presentation control unit (104) that presents the oral care product indicated by the inference results.

PSYCHOSOMATIC STATE EVALUATION DEVICE, POLICY PROPOSAL DEVICE, AND PSYCHOSOMATIC STATE EVALUATION METHOD

Absstract of: WO2026070511A1

This psychosomatic state evaluation device comprises: an information acquisition unit that acquires subject information including first information related to a phase of a menstrual cycle of a subject, and at least one of second information related to regularity of the menstrual cycle of the subject and third information related to premenstrual syndrome of the subject; and an evaluation unit that evaluates, on the basis of the subject information, the psychosomatic state of the subject in a prescribed phase of the menstrual cycle.

SYNTHETIC HEMOCOMPATIBLE VASCULAR GRAFTS MANUFACTURED FROM POLYVINYL ALCOHOL-BASED BIOMATERIALS

Absstract of: US20260091160A1

Synthetic hemocompatible vascular grafts manufactured from polyvinyl alcohol-based biomaterials containing crystalline segments of polyvinyl alcohol, which are long-term fully functioning vascular grafts that provide no activity towards immune systems in recognizing surfaces as foreign bodies that would normally lead to fibrosis, platelet activation and subsequent thrombi formation, and thus occlusion of the grafts.

FLUID-ABSORPTIVE GASTRORETENTIVE DOSAGE FORM FOR PROLONGED DRUG DELIVERY

Absstract of: AU2024327179A1

In this specification, a new design and formulation of an expandable dosage form is presented where the post-expansion mechanical properties and the drug release rate by the dosage form can be independently controlled. The dosage form generally comprises a fluid-absorptive, expandable solid core, a mechanically strengthening semi-permeable layer substantially encapsulating said fluid-absorptive core, and a drug-containing solid applied outside said encapsulated core.

Implant and method for covering large-scale bone defects for thorax

Absstract of: AU2026202035A1

Abstract The invention provides an implant for covering a thorax bone defect, comprising: 5 at least one lattice structure of individual lattice cells, each lattice cell comprising one or more ring elements, each ring element comprising a through-hole configured for receiving a fixation device, at least some of the ring elements of each lattice structure 10 being connected via non-linear bridge elements to one another, wherein the implant is made at least predominantly from a plastic material. ar b s t r a c t a r h e i n v e n t i o n p r o v i d e s a n i m p l a n t f o r c o v e r i n g a t h o r a x b o n e d e f e c t , c o m p r i s i n g : a t l e a s t o n e l a t t i c e s t r u c t u r e o f i n d i v i d u a l l a t t i c e c e l l s , e a c h l a t t i c e c e l l c o m p r i s i n g o n e o r m o r e r i n g e l e m e n t s , e a c h r i n g e l e m e n t c o m p r i s i n g a t h r o u g h - h o l e c o n f i g u r e d f o r r e c e i v i n g a f i x a t i o n d e v i c e , a t l e a s t s o m e o f t h e r i n g e l e m e n t s o f e a c h l a t t i c e s t r u c t u r e b e i n g c o n n e c t e d v i a n o n - l i n e a r b r i d g e e l e m e n t s t o o n e a n o t h e r , w h e r e i n t h e i m p l a n t i s m a d e a t l e a s t p r e d o m i n a n t l y f r o m a p l a s t i c m a t e r i a l

MEDICAL DEVICE HAVING A TEMPERATURE SENSITIVE ACTIVATION LABEL

Absstract of: US20260093944A1

A medical device has a medical tool and an activation label connected to the medical tool. The activation label has an activation code required for activating the medical device. A controller is connected to the medical tool and the controller is configured to receive an activation signal from a remote control device. The activation label has a temperature sensitive part that is configured to change appearance at a predetermined temperature condition, in particular such that it masks at least part of the activation code if the predetermined temperature condition is reached.

DIAGNOSIS AND MONITORING OF NEURODEGENERATIVE DISEASES

Absstract of: US20260094269A1

0000 Disclosed is a method for diagnosing a neurodegenerative disease in a subject. The method comprises obtaining from the subject a sample comprising at least one live blood cell, and optionally isolating at least one live blood cell from the sample. The method further comprises generating one or more multispectral or hyperspectral images of the at least one cell, and analysing spectral characteristics of autofluorescence from the at least one cell. Also disclosed is a system configured to aid in the detection or diagnosis of a neurodegenerative disease. Also disclosed is a method for selecting a subject for treatment for a neurodegenerative disease. Also disclosed is a method for monitoring the response of a subject to a therapeutic treatment for a neurodegenerative disease. Also disclosed is a protocol for monitoring the efficacy of a therapeutic treatment for a neurodegenerative disease.

SYSTEM AND METHOD FOR MULTI-MODAL DOSING DEVICE

Absstract of: US20260091177A1

Provided is a system and method for multi-modal dosing of a product. The system provides a control base for coupling to one of a plurality of different cartridges containing product, at least two cartridges having different modalities of delivery—the coupled control base and selected cartridge providing a dosing device. Each cartridge has at least a unique identifier, which may be read by the control base and correlated through a database to confirm that the user is authorized to use the cartridge, and use of the cartridge for a dose of product will not conflict with other products received by the user and known to the system. Cartridges that are not coupled to the control base are non-functional and cannot dispense product as intended with the system. An associated method of use is also provided.

DIAGNOSTIC INTRAORAL METHODS AND APPARATUSES

Absstract of: US20260090866A1

0000 Methods and apparatuses for taking, using and displaying three-dimensional (3D) volumetric models of a patient's dental arch. A 3D volumetric model may include surface (e.g., color) information as well as information on internal structure, such as near-infrared (near-IR) transparency values for internal structures including enamel and dentin.

METHOD OF COMPRESSING TISSUE WITHIN A STAPLING DEVICE AND SIMULTANEOUSLY DISPLAYING THE LOCATION OF THE TISSUE WITHIN THE JAWS

Absstract of: US20260090735A1

0000 A method of compressing tissue during a surgical procedure is disclosed. The method comprises obtaining a surgical instrument comprising an end effector, wherein the end effector comprises a first jaw and a second jaw, establishing a communication pathway between the surgical instrument and a surgical hub, and inserting the surgical instrument into a surgical site. The method further comprises compressing tissue between the first jaw and the second jaw, determining a location of the compressed tissue with respect to at least one of the first jaw and the second jaw, communicating the determined location of the compressed tissue to the surgical hub, and displaying the determined location of the compressed tissue on a visual feedback device.

SYSTEM AND METHOD FOR MONITORING RESPIRATORY RATE MEASUREMENTS

Absstract of: US20260090772A1

This disclosure describes, among other features, systems and methods for using multiple physiological parameter inputs to determine multiparameter confidence in respiratory rate measurements. For example, a patient monitoring system can programmatically determine multiparameter confidence in respiratory rate measurements obtained from an acoustic sensor based at least partly on inputs obtained from other non-acoustic sensors or monitors. The patient monitoring system can output a multiparameter confidence indication reflective of the programmatically-determined multiparameter confidence. The multiparameter confidence indication can assist a clinician in determining whether or how to treat a patient based on the patient's respiratory rate.

METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR REAL-TIME DETECTION OF SENSITIVITY DECLINE IN ANALYTE SENSORS

Absstract of: US20260095261A1

0000 Method, system and computer program product for providing real time detection of analyte sensor sensitivity decline is continuous glucose monitoring systems are provided.

NOVEL 3D PRINTING CONCEPT FOR PHARMACEUTICAL DOSAGE FORMS VIA SELECTIVE LASER SINTERING

Absstract of: WO2024240762A1

The present invention relates to a process for producing a Pharmaceutical dosage form by powder bed fusion selective laser 3-dimensional printing, in particular selective laser sintering 3-dimensional printing (SLS), and a pharmaceutical dosage form manufactured by that process.

Implants and method for forming an implant

Absstract of: MX2023000866A

Embodiments herein relate to a three-dimensional implant for tissue reconstruction or tissue augmentation for insertion into a patient. The implant comprises a plurality of strands forming a three-dimensional structure, which comprises a plurality of hollow channels. Each hollow channel comprises a plurality of sidewalls. A sidewall comprises a plurality of strand segments and a plurality of gaps arranged altematingly so that a gap is formed between adjacent strand segments of the sidewall. The gap comprises a gap length (gl) and a resting gap height (gh). The plurality of gaps are reversibly expandable gaps. Adjacent strand segments comprise a deflection capability (δ) based on an object to be received by the reversibly expandable gap. A radius (R) of the plurality of strands and a gap lengths (gl) of a reversibly expandable gap is based on a yield strength (δ_yield), the elastic modulus (E) of the material and a deflection capability δ of the adjacent strand segments forming the reversibly expandable gap.

Process for preparation methacrylated decm

Absstract of: WO2025042300A1

Process for methacrylation of dECM comprising placing a carbonate buffer with a concentration of 1M in the reaction vessel and heating to a temperature of 50 °C, adding dECM to the carbonate buffer to obtain a dECM solution with a concentration of 4% (w/v), sterilizing this solution by irradiation with radiation UV for 15 minutes, adding methacrylic anhydride in an amount of 0.5 mL/1g dECM and reacting at 50 °C for 1 h, then adding a phosphate-buffered saline solution to obtain a 5-fold dilution of the mixture, placing the obtained solution in dialysis tube, and then placing the dialysis tube in deionized water, this stage is carried out at a temperature of 40 °C for no longer than 4 days, after completing this stage, the solution contained in the dialysis tubes is transferred to aluminum trays and then placed at a temperature -80 °C for at least 3 hours, then the frozen solution is freeze-dried under the following conditions: shelf temperature 10 °C, pressure 0.1 mba, freeze-drying time 48 hours. The invention also relates to methacrylated dECM obtained by the above method and to the use of methacrylated dECM obtained by the above method in the bioprinting process.

SYSTEM AND METHOD FOR PROCESSING MEDICAL IMAGE DATA FOR GENERATING AN IMAGE COMPRISING A SIMULTANEOUS REPRESENTATION OF AN ARTERIAL, VALVULAR AND MYOCARDIAL STATE

Absstract of: EP4718375A1

The present invention relates to the field of medical imaging and in particular to a system (10) for processing medical image data for generating an image comprising a simultaneous representation of an arterial, valvular and myocardial state, wherein the system is adapted to perform the steps of obtaining 3D medical image data (S 101); identifying arterial, valvular and myocardial regions in the 3D medical image data by means of segmentation (S102); mapping the 3D medical image data to a 2D representation using a coordinate transform based on a spherical coordinate system with an origin depending on the identified valvular region and/or the identified arterial region (S104); generating a combined 2D image (50) indicative of the arterial-, valvular and myocardial state based on the 2D representation as an output (S104). The present invention further relates to a corresponding method (100) and computer program.

METHOD AND SYSTEM FOR DETERMINING A CONFIDENCE SCORE OF A DENTAL WORKFLOW

Absstract of: EP4718464A1

A computer-implemented method for determining a confidence score (607) of a digital dental workflow (100) is disclosed. The method comprises receiving scan data representative of a dental situation, wherein the scan data comprises color images and near-infrared images. The method further comprises determining a quality measure (106) of the received scan data. Further, the method comprises generating enhanced diagnostic images based on at least the near-infrared images of the scan data and determining a quality measure of the enhanced diagnostic images. The method further comprises identifying a dental condition in the dental situation based on the enhanced diagnostic images and determining a probability value (108) representing a likelihood that the dental condition is identified correctly. The method further comprises determining the confidence score (607) of the digital dental workflow (100) based on the quality measure (106) of the received scan data, the quality measure of the enhanced diagnostic images and the probability value (108).

DEVICES, SYSTEMS, AND METHODS ASSOCIATED WITH ANALYTE MONITORING DEVICES AND DEVICES INCORPORATING THE SAME

Absstract of: EP4717172A1

Analyte monitoring systems, devices, and methods associated with analyte monitoring devices, and devices incorporating the same are provided. Various graphical user interfaces (GUI) and navigation flows are provided for performing various features, activities, functions, etc., associated with the analyte monitoring device or system. Intuitive navigation is provided to enhance the interpretation of analyte measurements.

フロー療法機器内の酸素供給を制御するための方法及びシステム

Absstract of: EP4445935A2

0001 The present disclosure provides for a control system for a flow therapy apparatus. The control system can control delivery of a fraction of delivered oxygen (FdO2) to a patient. The control system can maintain the FdO2 at a target level during a therapy session. The control system can automatically control an oxygen inlet valve in order to control the flow of oxygen to the patient.

INSTRUMENT SHAFT WITH MULTIPLE CHANNELS AND PRODUCTION THEREOF

Absstract of: EP4717147A2

Die Offenbarung bezieht sich auf ein medizinisches Instrument zur Bereitstellung eines Zugangs zum Körperinneren, insbesondere Spatel (12) für ein endoskopisches Instrument (10), mit einem Schaft (14) mit einem langgestreckten Grundkörper (16), wobei sich der Grundkörper (16) zwischen einem distalen Ende (30) und einem proximalen Ende (32) des Schaftes (14) erstreckt, und einem mit dem Grundkörper (16) des Schaftes (14) an dessen proximalem Ende (32) gekoppelten Griff (20), wobei der Schaft (14) zumindest einen ersten Kanal (40) und einen zweiten Kanal (42) definiert, die sich durch den Schaft (14) erstrecken, wobei der erste Kanal (40) eine Passage für chirurgische Instrumente durch den Schaft (14) hindurch bereitstellt, wobei der zweite Kanal (42) zur Aufnahme einer Beobachtungsoptik (46) ausgebildet ist, und wobei dem zweiten Kanal (42) zumindest ein Nebenkanal (78, 80) benachbart ist, der mit dem zweiten Kanal (42) verbunden ist. Die Offenbarung bezieht sich ferner auf ein Verfahren zur Herstellung eines solchen Instruments.

RESPIRATORY VENTILATION APPARATUS

Absstract of: EP4717294A2

0001 A respiratory ventilation apparatus includes a gas pressurization unit located within a main body. A connecting piece is configured to fix the gas pressurization unit within an internal space of the main body and to damp its vibration. The connecting piece comprises a fixing part and a connecting part. The fixing part has a sheet structure with an aperture for the passage of pressurized respiratory gas. The connecting part has a tubular structure and fluidly connects an outlet port of the gas pressurization unit to the aperture of the fixing part. The connecting part and the fixing part are made of different materials, allowing the fixing part to be rigid for secure mounting and the connecting part to be flexible for vibration damping.

ENHANCED PLATEN FOR PHARMACEUTICAL COMPOUNDING

Absstract of: EP4717246A2

A system for preparing and administering a prescribed fluidic pharmaceutical compound, such as a chemotherapy compound, includes a scale having a platen. The scale is in communication with a user display for displaying an output of the scale. An image capture device having a field of view for capturing at least one image of an object placed on the platen is provided in communication with the user display for displaying the captured image. The platen may include a visual identifier for identifying a portion of the field of view of the image capture device. The platen may also include a tackifier or absorbent material. The platen may be formed of a light-transmissible material.

CUSTOM PATIENT INTERFACE AND METHODS FOR MAKING SAME

Absstract of: EP4717157A2

0001 The present invention discloses a patient interface for sealed delivery of a flow of air at a continuously positive pressure with respect to ambient air pressure to an entrance to the patient's airways comprising: a mask assembly comprising a frame component having an opening to a delivery tube and having a plurality of vent holes along an outer surface of the frame component above the opening; a sealing element coupleable to the mask assembly and configured to be in contact with the patient's face in use, wherein the frame component and the sealing element form a plenum chamber that defines a cavity by a perimeter of the patient's nares; and a positioning and stabilising structure, coupled to the mask assembly, the positioning and stabilising structure being configured to maintain the sealing element in sealing contact with an area surrounding the entrance to the patient's nares while maintaining a therapeutic pressure at the entrance to the patient's nares; wherein at least one of the mask assembly, the sealing element and the positioning and stabilising structure is configured to compensate for skin movement and deformation.

PERFORMANCE VISUALIZATION METHODS AND DIAGNOSTIC LABORATORY SYSTEMS INCLUDING SAME

Absstract of: EP4717173A2

0001 Methods of visualizing performance of a diagnostic laboratory system are provided. The methods include displaying on a display, an image representing a layout of a plurality of laboratory analyzers included within the diagnostic laboratory system, and overlaying the image with a dynamically-changeable color overlay that indicates a performance for the plurality of laboratory analyzers over a period of time via using changeable colors. Systems including color-changeable overlays are provided as are other aspects.

一种用于慢性创面修复的复合型水凝胶敷料及其制备方法和应用

Nº publicación: CN121754718A 31/03/2026

Applicant:

东华大学郑州大学第五附属医院

Absstract of: CN121754718A

本发明属于组织工程与创面修复领域，涉及一种用于慢性创面修复的复合型水凝胶敷料及其制备方法和应用，该制备方法包括：S1、将肉桂醛分散在明胶水溶液中，反应充分后透析至溶液澄清；冷冻干燥后得到肉桂醛接枝的改性明胶；S2、将祛褥生肌粉、S1得到的肉桂醛接枝的改性明胶、甲基丙烯化明胶、光引发剂在PBS溶液中混合，得到混合溶液；S3、向S2得到的混合溶液中加入Ga(NO3)3·6H2O溶液，得到水凝胶前驱体溶液；S4、使用S3得到的水凝胶前驱体溶液进行3D打印，光固化，得到复合型水凝胶敷料。本发明中，通过GelMA、CA‑Gel与镓离子形成的三维网络对药粉进行包埋与缓释，实现对慢性创面的高效抗菌、促愈和结构支撑，提升治疗效果与使用安全性。