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302
results.
Updated on
24/04/2026 [07:12:00]
Results 150 to 175 of 302
Absstract of: CN121774869A
本发明属于生物医药与先进制造交叉技术领域，具体涉及一种用于药物缓释的4D打印胃滞留制剂。所述的4D打印胃滞留制剂由包含药物和形状记忆聚合物的复合材料经4D打印制成；所述形状记忆聚合物为聚乳酸（PLA）与聚乙烯醇（PVA）的共混物，且所述PLA与PVA的配比被配置为调控所述制剂在胃部环境中的药物释放行为与物理滞留性能；所述的胃滞留制剂设置有第一永久形状和第二临时形状，且第一永久形状可以通过第二临时形状在触发温度下触发得到，所述触发温度为35℃‑40℃。该装置可在人体胃部温度（37℃）和体液环境下被触发，发生从紧凑临时形状到扩张永久形状的转变，且能实现在胃内滞留8h，释药后能安全排出，实现长效胃内滞留和药物控制释放。
Absstract of: CN121777421A
本发明涉及生物制造与组织工程领域，具体公开了一种多生物结构特征的人工血管制造方法，包括：构建人工血管的参数化模型，所述模型定义了血管的多层生物结构特征并明确其与打印路径的对应关系；基于模型生成控制跨尺度径向3D打印的G代码，通过同一回转轴接收装置及联动控制，在一次成形过程中实现宏观层状结构与微观纤维网络结构的一体化制造。其中，通过失稳态同轴挤出结合网格型紧密路径，精确成形具有波纹力学特性的内外弹性膜；通过螺旋型大导程路径堆积载有平滑肌细胞的毫米级纤维，构建具备收缩功能的中膜；通过网格型宏观近场直写静电纺丝构筑纳米级纤维网络，形成仿生外膜以促进细胞粘附。
Absstract of: US20260094690A1
Systems and methods for the diagnosis and treatment of developmental delay and/or disorders in children for the purpose of early diagnosis and treatment of children to promote the development of at least one of fine motor skills, gross motor skills, sound articulation and sound discrimination skills, receptive language, expressive language, phonological awareness, phonological processing to prevent reading failure, academic underachievement, color blindness, attention issues and social emotional dysregulation. The systems and methods resulting in the generation of a referral of the individual for services in areas where the evaluation results were deficient to promote at least one of fine motor skills, gross motor skills, sound articulation, and sound discrimination skills.
Absstract of: US20260090892A1
An orthopedic knee prosthesis includes a femoral component, a tibial bearing, a tibial component, a first magnetic portion associated with the femoral component and including a first pole having a first pole polarity the first magnetic portion not physically interrupting any articulating portion of the curved medial condyle surface or curved lateral condyle surface, and a second magnetic portion associated with one or both of the tibial bearing and/or the tibial component and including a second pole having a second pole polarity, the second pole polarity the same as the first pole polarity, the second magnetic portion not physically interrupting any articulating portion of the concave medial bearing surface or concave lateral bearing surface, wherein the first pole and the second pole are in sufficient proximity to each other such that a magnetic repulsive force is present therebetween.
Absstract of: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Absstract of: US20260090774A1
A system (200) for providing guidance information for an implantable device extraction procedure, is provided. The system includes one or more processors (210) configured to: receive (S110) attenuation data (110) representing an implantable device (120) in an anatomical region, the attenuation data defining X-ray attenuation within the anatomical region; analyze (S120) the attenuation data (110) to determine an amount of adhesion (130) between the implantable device (120) and a tissue (140) contacting the implantable device; and output (S130) guidance information for the implantable device extraction procedure based on the amount of adhesion (130).
Absstract of: US20260090858A1
A surgical hub comprising a processor. The processor configured to perform a number of actions. A surgical task may that uses a medical instrument during a medical procedure may be determined based on contextual data. A technique employed by a user during the surgical task may be determined. A performance of the technique employed by the user relative to a baseline may be analyzed using the contextual data. A corrective action may be determined when the performance of the technique deviates from the baseline. A data priority based on the corrective action may be determined. A first message for a display may be generated based on the data priority. A second message for the medical instrument may be generated to cause an adjustment of one or more operational parameters when the performance of the technique deviates from the baseline.
Absstract of: US20260090584A1
A controller includes a processor and a memory storing instructions configured to cause the processor to receive emission test data of a test aerosolization system corresponding to a test aerosolizer power or a range of test aerosolizer powers of a test aerosolizer of the test aerosolization system and a test concentration or a range of test concentrations, receive operation data of a user aerosolization system corresponding to an operation duration based at least in part on an input signal from a user, the operation data comprising at least a concentration of a consumable included in the user aerosolization system and a aerosolizer power level of a aerosolizer of the user aerosolization system during the operation duration, estimate a emission per operation duration based at least in part on the operation data and the emission test data, and generate a signal indicative of the estimated emission per operation duration.
Absstract of: US20260091161A1
There is provided a hydrogel string for encapsulating a biological material. The hydrogel string has a thiol-ene crosslinked polymer with a first side-chain functionalized backbone polymer functionalized with an activated alkene crosslinked with a free or protected thiol-containing group present on a second side-chain functionalized backbone polymer. The biological material is encapsulated within the thiol-ene crosslinked polymer.
Absstract of: WO2026066943A1
According to embodiments of the present disclosure, a coordinate registration method, a device and a surgical navigation system are provided. The method comprises: acquiring position information of one or more first pixels in an image coordinate system; determining a first direction in a navigation coordinate system based on first information acquired by a first sensor, wherein the first direction corresponds to the direction of the first coordinate axis in the image coordinate system; determining three-dimensional coordinates of the first number of first points in the navigation coordinate system based on second information of the target object collected by a second sensor; registering the image coordinate system with the navigation coordinate system, based on the position information of the first pixels in the image coordinate system, the first coordinate axis in the image coordinate system, the three-dimensional coordinates of the first points in the navigation coordinate system, and the first direction.
Absstract of: US20260090751A1
A wearable device includes: an air tube; an air inlet provided at one end of the air tube to inject or discharge air from the air tube; a driving unit configured to inject or discharge air into or from the air tube through the air inlet; a silicone tube disposed inside a housing of the driving unit and connected to the air inlet; a sensor module positioned inside the silicone tube and including a piezoelectric element configured to sense pressure; a first communication unit; a first artificial intelligence (AI) model unit; and a first processor disposed inside the silicone tube and operably connected to the driving unit, the sensor module, and the first AI model unit.
Absstract of: WO2026070984A1
Problem To provide, in a relatively inexpensive manner, a polymerization molding model which has high molding accuracy and surface density and enables easy release from a molded resin after polymerization molding, and a polymerization molding method. Solution A molding model for polymerization molding of dentures comprises: a thin-skin cup model having an internal space which is opened downward by means of a three-dimensional recessed surface on the back side of a three-dimensional molding part made of a thin-skin body having a constant thickness; and a dental plaster that is filled in the internal space opened downward of the thin-skin cup model and is solidified. After polymerization molding, the solidified dental plaster is destroyed and removed from the internal space; the three-dimensional molding part made of the thin-skin body is bent or folded and deformed, and the thin-skin body of the three-dimensional molding part is peeled from a polymerized main molded resin body resulting from denture base molding for demolding.
Absstract of: US20260094487A1
0000 Embodiments of the present invention comprise a device, system, and method for prescribing and dispensing products. A device may have a graphical user interface and a speaker for providing output to a user. The device may have a camera, microphone, a keyboard, and a diagnostic tester for receiving input from the user. Input from the user may be images of the user that are analyzed by a memory and a processor to determine a suggested product for the user. A user confirmation and/or external confirmation from a licensed medical professional may be provided. Upon receiving a confirmation, the suggested product may be dispensed from the device. Interaction between the user and the device may be aided by the depiction of an avatar on the graphical user interface. The avatar may display expressions that are dynamically updated based on input from the user.
Absstract of: US20260091555A1
Dental restoration technologies include dental prosthesis components such as implants, abutments, crowns, and the like that are mapped to a patient's mouth prior to and during installation. Fabricating at least a portion of one or more components of the dental prosthesis using a fully calibrated and characterized fabricator can reduce sources of error that affect the success of fabrication and installation processes. The components of the dental prosthesis are represented by library files that are tailored to reflect particular characteristics of the components of the prosthesis to be fabricated, the fabricator, the material used during fabrication, and/or the environment surrounding the fabricator. The library files may be determined based on an acquired scan of the patient and/or based on inputs received from a user during the design process. The library files may be generated using virtual modeling techniques, and/or based on a component design that falls within pre-determined parameters.
Absstract of: US20260094291A1
0000 Systems and methods are disclosed herein for using structure from motion (SfM) techniques to reconstruct three-dimensional (3D) surface models of tubular patient anatomies, such as the larynx and trachea, from clinical endoscopy videos. The disclosed methods may improve understanding of upper airway disease including vocal fold paralysis, laryngeal cancer, subglottic hemangiomas, subglottic stenosis, tracheal stenosis, tracheal cartilaginous sleeves, complete tracheal rings and tracheomalacia, and allow for quantitative analysis of complex laryngotracheal geometries. Quantitative measures of airway caliber and shape, which are critical for diagnostic purposes, may be obtained using the disclosed methods as a cost-effective and radiation-free alternative to relying on imaging studies. Results have demonstrated excellent resolution of reconstructions, when compared to high-resolution computed tomography (CT) scans (surface errors <0.300 mm).
Absstract of: US20260090894A1
An implant can be configured to transition between a first stable state and a second stable state. The implant can include a first surface and a second surface coupled to the first surface. The first surface can include a first structure configured to form a stable planar shape during the first stable state of the implant and to form a stable three-dimensional (“3D”) shape during the second stable state of the implant. The second surface can include a second structure configured to form a stable planar shape during the first stable state of the implant and to form a stable 3D shape during the second stable state of the implant.
Absstract of: US20260094687A1
An infusion pump programming system with automated dose evaluation, real-time infusion rate calibration, and safety validation. The infusion pump programming system comprises a computing device having a processor and a memory for storing instructions that are executed by the processor. The computing device is communicatively coupled with a server via a network. The infusion pump programming system automates recalibration of multi-step infusion protocols whenever rate, volume, or total infusion time is modified, eliminating manual re-entry and reducing evaluation errors. The infusion pump programming system preserves clinical logic and sequencing of infusion steps such as ramp-up, main infusion, ramp-down, and flush phases ensuring that safety thresholds and dosing rules remain intact during reevaluation. The infusion pump programming system has wide commercial applicability across hospitals, outpatient centers, pharmacies, and home-care infusion services. The infusion pump programming system substantially reduces staff time spent on manual infusion evaluations and documentation.
Absstract of: US20260094688A1
Information comprising physical settings for a particular radiation treatment platform (such as machine control points) form a training corpus. A neural network is trained using that training corpus. By one approach, the training corpus does not include any information that pertains to any radiation treatment platform other than the particular radiation treatment platform. The training may be repeated as a function of at least one of a passage of time, a particular number of therapeutic uses of the particular radiation treatment platform, and/or completion of at least one maintenance activity. A radiation treatment plan can be optimized to provide optimized plan control points. These optimized plan control points can be mapped to corresponding machine control points as a function, at least in part, of the aforementioned trained neural network.
Absstract of: US20260090776A1
0000 An information processing apparatus includes a processor, in which the processor acquires a plurality of pieces of imaging data corresponding to radiation having different energies, and generates a color image from the plurality of pieces of imaging data, the color image having a color assigned based on an index obtained using energy information of the radiation.
Absstract of: US20260090865A1
Provided herein are articles, systems, kits, and methods for generating calibrated dental arch images by processing intraoral scanning images and a dental arch calibration jig image (e.g., generated as a single image without stitches). In certain embodiments, a library of intraoral scanning images are generated by scanning a dental arch calibration jig in a subject's mouth. In particular embodiments, at least some of the first library of images of the calibration jig are stitched together to generate a stitched intraoral scan 3D jig image, at least a portion of which is spatially aligned to at least a portion of said 3D dental arch calibration jig image to generate a calibrated dental arch image.
Absstract of: US20260090841A1
0000 One or more computing devices, systems and/or methods are provided. In some examples, one or more images of a brain of a patient may be received. One or more anatomic landmarks in the one or more images may be determined. A hemorrhage region in the one or more images may be identified. A normalized hemorrhage map indicative of the hemorrhage region may be generated based upon the one or more anatomic landmarks and the hemorrhage region in the one or more images. A spatial representation of the hemorrhage region may be generated based upon a comparison of the normalized hemorrhage map to a dissimilarity heat map. A treatment plan for the patient may be determined based upon the spatial representation of the hemorrhage region.
Absstract of: US20260094276A1
Systems and methods are provided for processing image data generated by a medical imaging device such as an ultrasound or echocardiogram device and processing the image data using artificial intelligence and machine learning to determine a presence of one or more congenital heart defects (CHDs) and/or other cardiovascular anomalies in the image data, to identify anatomy, detect and/or identify motion, and/or to determine key-point and/or contour detection. The image processing system may be used to detect CHDs and/or other cardiovascular anomalies in a fetus. The image data may be processed using a spatiotemporal convolutional neural network (CNN). The spatiotemporal CNN may include a spatial CNN for image recognition and a temporal CNN for processing optical flow data and/or image data. The outputs of the spatial CNN and the temporal CNN may be fused (e.g., using late fusion) and/or may be processed by a spatiotemporal CNN.
Absstract of: WO2026071501A1
An electronic device is disclosed. The electronic device of the present disclosure comprises: a microphone; at least one sensor including a sensing circuit; a display; at least one processor including a processing circuit; and a memory for storing instructions. The instructions, when executed individually or collectively by the at least one processor, may cause the electronic device to: detect an abnormal behavior on the basis of at least one of user speech acquired through the microphone and sensing data acquired by the at least one sensor; identify an expected disease corresponding to the abnormal behavior on the basis of the detection of the abnormal behavior; in order to determine whether the expected disease has occurred, acquire a question related to the expected disease and a correct answer corresponding to the question as output data of an artificial intelligence model stored in the memory, by using, as input data for the artificial intelligence model, data on the expected disease and personal data including at least one of the user speech and the sensing data; provide the question; receive a user answer to the question; determine whether the expected disease has occurred, on the basis of a comparison between the user answer and the correct answer; and provide a determination result of whether the expected disease has occurred, wherein the artificial intelligence model is trained to use diagnostic test forms of a disease and personal data as input data to acquire a qu
Absstract of: WO2026070492A1
This skin state estimation device comprises: a menstrual cycle information acquisition unit that acquires menstrual cycle information pertaining to the length of a menstrual cycle and/or fluctuations in the menstrual cycle of a subject; a mind-and-body/lifestyle habit information acquisition unit that acquires mind-and-body/lifestyle habit information pertaining to one or more of the physical state, mental state, and lifestyle habit of the subject; and an estimation unit that estimates the skin state of the subject on the basis of the menstrual cycle information and the mind-and-body/lifestyle habit information.
Nº publicación: JP2026057539A 02/04/2026
Applicant:
株式会社湯山製作所
Absstract of: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
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