Alerta

3D Functional wrist protector with 3D printed pad to prevent and alleviate carpal tunnel syndrome

Absstract of: KR20250146085A

본 발명은 손목터널증후군 예방 및 완화를 위한 3D 프린팅 패드가 마련된 기능성 손목보호대에 관한 것으로서, 사용자의 손과 손목에 착용할 수 있도록 형성되어 있는 착용부와, 상기 착용부의 상부와 하부에 각각 형성되어 손목이 꺾이지 않은 상태로 지지될 수 있도록 하는 지지부를 포함하는 것을 특징으로 한다.

Methods for preparing porous scaffold for cell culture comprising marine-derived protein

Absstract of: KR20250146682A

본 발명은 (a) 해양 생물 유래 젤라틴과 알지네이트를 증류수에 녹여 젤라틴-알지네이트 혼합용액을 제조하는 단계; (b) 상기 젤라틴-알지네이트 혼합용액에 광개시제와 전자수용체를 첨가하여 전구체 용액을 준비하는 단계; (c) 상기 전구체 용액의 광가교를 유도하여 하이드로젤을 형성하는 단계; (d) 상기 하이드로젤의 이온결합을 유도하여 이중 가교 구조체를 형성하는 단계; 및 (e) 상기 이중 가교 구조체를 유기산 용액에 침지시켜 알지네이트를 제거함으로써 하이드로젤 다공성 구조체를 형성하는 단계;를 포함하는 3D 다공성 세포 지지체의 제조방법에 관한 것이다. 이에 의하여, 본 발명의 해양 생물 유래 단백질을 이용한 3D 다공성 세포 지지체의 제조방법은 근육세포와 유사한 형태로 세포배양이 이루어질 수 있을 뿐 아니라 세포의 부착이 용이하고 증식이 균일하게 이루어져 3차원으로 세포 배양을 매우 효율적으로 수행할 수 있으며, 해양 생물을 식재료로 이용할 때 발생하는 생선 비늘, 생선 껍질 등의 폐기물로부터 제조되는 젤라틴 재료를 활용하여 환경오염을 줄이고 비용도 절감할 수 있다.

3D DRUG AUTO SYNTHSIZING MODULE AND MANUFACTURING USING 3D PRINTING THE SAME

Absstract of: KR20250144316A

본 발명은 의약품 자동합성 모듈 및 3D 프린팅을 이용한 의약품 자동합성 모듈 제조방법에 관한 것으로, 본 발명의 일 측면에 따르면 의약품 자동합성 모듈은 지르코니아 소재로 이루어지고, 메인 유로 및 상기 메인 유로와 연결된 복수의 연결 유로를 포함하는 합성모듈 바디, 상기 합성모듈 바디에 삽입되도록 구성되고, 상기 복수의 연결 유로를 개폐하도록 구성된 밸브 조립체, 상기 벨브 조립체와 상기 합성모듈 바디 사이를 실링하는 제1 탄성링을 포함한다.

의료용 조직 랩

Absstract of: AU2023370241A1

The invention relates to the field of medical tissue wraps for internal anatomical structures as well as a use and a method of treating a nerve lesion using such medical tissue wraps. In particular, the invention relates to medical tissue wraps for neural tissue supporting the repair of peripheral nerve lesions by facilitating secure application of the medical tissue wrap. Accordingly, a medical tissue wrap (10) for an internal anatomical structure of a mammal is suggested, wherein the medical tissue wrap (10) is formed by a coiled wall (12) having a circumferential inner end portion (20) and a circumferential outer end portion (22) extending around and overlapping the circumferential inner end portion (20). The wall (12) thereby defines a longitudinal through-hole (16) for accommodating a portion of the anatomical structure. According to one aspect of the invention, the circumferential outer end portion (22) is radially spaced-apart from the circumferential inner end portion (20) by a discontinuous spacing in the circumferential direction. According to a further aspect, the tissue wrap comprises a structural outer surface modification at opposing longitudinal end portions of its wall.

METHOD FOR PRODUCING A DENTAL RESTORATION

Absstract of: KR20240080147A

The present invention relates to a method for manufacturing a dental restoration, comprising the steps of: (s101) determining a first space area of a dental restoration subject to a higher load than a second space area of the dental restoration; and (s102) manufacturing the dental restoration in the first space area with a different manufacturing material from the second space area.

SYSTEMS AND METHODS FOR OPTIMIZED PATIENT SPECIFIC TISSUE ENGINEERING VASCULAR GRAFTS

Absstract of: US2025009937A1

It has been established that optimizing cell seeding onto tissue engineering vascular grafts (TEVG) is associated with reduced inflammatory responses and reduced post-operative stenosis of TEVG. Cell seeding increased TEVG patency in a dose dependent manner, and TEVG patency improved when more cells were seeded, however duration of incubation time showed minimal effect on TEVG patency. Methods of engineering patient specific TEVG including optimal numbers of cells to maintain graft patency and reduce post-operative stenosis are provided. Closed, single-use customizable systems for seeding TEVG are also provided. Preferably the systems are custom-designed based on morphology of the patient specific graft, to enhance the efficacy of cell seeding.

功能化丝素蛋白基生物墨水、仿生软骨水凝胶及其制法

Absstract of: CN120754319A

本发明属于生物材料与组织工程技术领域，涉及一种功能化丝素蛋白基生物墨水、仿生软骨水凝胶及其制法。该墨水含有引发剂、SFMA、GelMA、PEGDA和OBC，各组分的配比严格控制；将该墨水与干细胞混合均匀后，引发固化交联反应，制成多重仿生软骨水凝胶。该水凝胶包括多重网络结构水凝胶以及同时分散在多重网络结构水凝胶中的OBC及干细胞，具有和真实软骨组织匹配的压缩模量以及多孔结构。本发明提供的功能化丝素蛋白基生物墨水及多重仿生软骨水凝胶，解决了现有技术中供体不足、免疫排斥、仿生维度单一、力学性能不匹配等问题，能实现高精度打印并高效促进软骨再生。

一种带有螺硫吡喃基团的聚氨酯丙烯酸酯及其合成方法和应用

Absstract of: CN120757748A

本发明提供了一种带有螺硫吡喃基团的聚氨酯丙烯酸酯及其合成方法和应用，涉及义齿基托材料技术领域。带有螺硫吡喃基团的聚氨酯丙烯酸酯中将螺硫吡喃的C‑S弱共价键引入聚氨酯丙烯酸酯主链中，利用其在外力作用下易发生均裂的特性来耗散能量，并通过自由基介导的点击反应实现链间交联，从而增强机械强度，使其适用于义齿基托、口腔修复体、生物医学植入物等领域。

一种运用3D打印技术制作可降解的乳房植入物的方法

Absstract of: CN120756090A

本申请提供了一种运用3D打印技术制作可降解的乳房植入物的方法，包括以下步骤：在3D打印喷头的加热腔内灌注打印材料；对加热腔加热至温度到达预设温度时3D打印设备开始打印工作，包括打印喷头的喷嘴挤出打印材料，并按预设程序在打印平台上方移动，保持加热腔温度稳定在预设温度；预设程序包括打印路径以预设图形的中心为起点，沿径向从内向外逐层打印，完成预设图形最后一层时打印工作结束；停止对加热腔的加热。通过加热腔稳定持续的加热，材料分子量逐渐减小，结合3D打印方法自预设图形由内向外逐层打印，使得乳房植入物的分子量自中心向外层逐层减小，解决了现有手段制作的乳房植入物的降解方向与细胞再生进程无法动态协同的问题。

一种仿生灯笼框架复合内固定装置及制备方法

Absstract of: CN120753772A

本发明公开了一种仿生灯笼框架复合内固定装置及制备方法，涉及骨科医疗器械技术领域，包括植入体和多棒桥接结构，多棒桥接结构由多个纵向连接棒与横向锁定钉组成，植入体由多个多层级仿生结构组成，多层级仿生结构包括两个对称设置的六边形上下层结构以及设置在两个六边形上下层结构之间的中间螺旋层结构。本发明从蜂窝与耗牛角宏微观结构中受到启发，采用耦合仿生技术制备出的多层级仿生结构具有优异的力学性能，缓冲吸振能力强，可有效匹配天然骨力学性能，可有效避免患者植入后二次损伤和“应力屏蔽”效应，通过电化学沉积方法引入的复合涂层弥补了单一植入体结构生物相容性不足、抗菌性不足、成骨分化能力弱的问题。

一种距下关节固定装置

Absstract of: CN223416347U

本实用新型提供了一种距下关节固定装置，属于医疗器械技术领域。该距下关节固定装置包括足托，足托套设在穿戴者的足跟部；足托包括底板以及设置在底板两侧顶端的第一侧板与第二侧板，第一侧板与第二侧板相对向内折弯，第一侧板与第二侧板顶端分别向底板方向凹陷形成有凹槽；第一侧板与第二侧板与穿戴者的脚踝相贴合。该距下关节固定装置结构简单，适应性好，能充分开放前足活动空间，减少穿戴不适感，达到用户自我锻炼重塑肌肉韧带及行走发力问题，安全性高。

錠剤印刷装置及び錠剤印刷方法

Absstract of: JP2025150039A

【課題】効率よく錠剤に印刷を行うことを可能にする。【解決手段】実施形態に係る錠剤印刷装置は、搬送ベルトと前記搬送ベルトを回転可能なプーリとを備え、錠剤を前記搬送ベルト上に吸着保持して搬送する搬送装置と、前記搬送装置により搬送される前記錠剤に印刷を行うインクジェットヘッドと、前記搬送ベルトを清掃する清掃装置と、を有し、前記清掃装置は、前記搬送ベルトの一部を覆うボックスと、前記ボックス内に設けられ、前記搬送装置に向けて気体を吹き付ける気体吹付装置と、前記気体吹付装置により除去された前記搬送装置に付着した異物を吸引除去する気体吸引部と、を備え、前記気体吹付装置は、前記プーリの外周の前記搬送ベルトの外表面に対して前記気体を吹き付けることを特徴とする。【選択図】図１

Kieferorthopädisches Behandlungsgerät

Absstract of: DE102024109729A1

Ein kieferorthopädisches Behandlungsgerät zur Behandlung einer Zahnfehlstellung durch Distalisierung der Molaren besitzt zwei Gleitröhrchen, ein die Gleitröhrchen verbindendes Schubelement und ein im Bereich eines ersten der Gleitröhrchen angeordnetes Befestigungselement zum Einhängen eines Gummizugs. Die Gleitröhrchen weisen dabei einen nicht-kreisrunden, insbesondere rechteckigen Innenquerschnitt auf und sind mit ihren Mittelachsen entlang einer gegebenenfalls gebogenen Linie orientiert, sodass ein Führungsbogen entsprechenden Querschnitts hindurchgeführt werden kann und das Gerät gleitverschieblich jedoch rotationsinvariant auf dem Führungsbogen geführt wird.

ORTHODONTIC SYSTEMS AND METHODS OF USING SAME

Absstract of: WO2025210397A1

In some embodiments, apparatuses and methods are provided herein useful to orthodontic systems. In some embodiments, an orthodontic system comprises a registration assembly comprising a first main body, at least one registration feature configured to contact a feature in a patient's mouth to align the orthodontic system in the patient's mouth, and a first mating element including at least one post extending from the first main body, and an appliance assembly comprising a second main body, a plurality of support structures extending from the second main body, a plurality of orthodontic appliances secured to the second main body via the plurality of support structures, and at least one aperture extending into the second main body, wherein the at least one aperture is configured to mate with the first mating element.

SYSTEM FOR CONTROLLABLE RELEASE IN 3D-PRINTED COLON TARGETING (CORR3CT) ORAL DOSAGE FORM

Absstract of: US2025312281A1

An oral dosage form for controllable release and method of forming are described. The oral dosage form includes a core layer including an active ingredient and a plurality of outer shell layers surrounding the core layer, the plurality of outer shell layers configured to disintegrate at a pH above a threshold. The method of forming the oral dosage form includes forming a core formulation paste including an active ingredient and forming an outer shell formulation paste configured to disintegrate at a pH above a threshold. The method further includes forming a wet tablet by sequentially depositing the outer shell formulation paste and the core formulation paste. The wet tablet is subsequently dried and cooled to produce the oral dosage form.

Method for Modeling Humeral Anatomy and Optimization of Component Design

Absstract of: US2025312163A1

Stemless components and fracture stems for joint arthroplasty, such as shoulder arthroplasty, are disclosed. Also, methods and devices are disclosed for the optimization of shoulder arthroplasty component design through the use of medical imaging data, such as computed tomography scan data.

IMPLANT COMPRISING NONBIOLOGIC PORTION AND BIOLOGIC PORTION

Absstract of: US2025312159A1

In one aspect, an implant for replacing subject tissue includes a nonbiologic portion and a biologic portion grown on the nonbiologic portion. The biologic portion may be grown on the nonbiologic portion before being implanted in the subject. The nonbiologic portion may comprise a porous metal substrate (e.g., scaffolding). The nonbiologic portion may be formed by 3D printing (i.e., additive manufacturing). The nonbiologic portion may be patient-specific. A robot may be used to shape the implant before implantation and/or to shape bone being replaced/resurfaced.

Apparatus and Methods for Small Joint and Bony Defect Replacement

Absstract of: US2025312160A1

Apparatus and methods for joint and bony segment replacement may utilize additive manufacturing (e.g., 3D printing) of various anatomic constructs with PEEK/zeolite/ion (PZI) material. Heavy metal ion loading options may be utilized which may provide differing properties to different surfaces of the resultant apparatus. Moreover, using the PZI material, the apparatus being implanted in joint and bony segment replacement may favorably manipulate the biologic microenvironment in which it may be implanted. Further, through use of PZI material, current large joint replacement options also may be disrupted including, but not limited to, modifications of the joint replacement itself, and the augments and supporting joint reconstruction devices used in bone loss situations. Methods for joint and bony segment replacement may provide mixing two or more types of PZI material together through an additive manufacturing process; and introducing the mixture as part of an implantable apparatus.

SERIES OF DEVICES FOR PREPARING THE DISPLACEMENT, IN PARTICULAR A PERMANENT DISPLACEMENT, OF THE OCCLUSAL PLANE OF A PERSON, AND ASSOCIATED METHODS

Absstract of: US2025312125A1

A series (100) of devices for assisting in the displacement of the chewing plane of a person (P) is explained, comprisingat least two devices (10),wherein the devices (10) each comprise at least one jaw device (11, 12),wherein the at least one jaw device (11, 12) comprises an upper jaw device (11) and/or a lower jaw device (12),and wherein the devices (10) are designed to be worn by the person (P) according to a predetermined sequence.In at least one device (10.1, 10.2), the at least one jaw device (11, 12) comprises at least one height element on a first side. At least two contact areas, preferably local contact areas, are formed on the at least one height element at mutually different positions of molar elements. At least one further contact area is formed on a second side of the at least one jaw device (11, 12), in particular a further local contact area. The at least three contact areas define the plane (GE),wherein the plane (GE) deviates from a starting chewing plane of the person (P) or from a current chewing plane of the person (P) with respect to its inclination changed by the at least one height element in a frontal section or sagittal section and/or deviates with respect to its height position changed by the at least one height element, andwherein in at least one other device of the series (100) a different inclination in a frontal section or sagittal section and/or a different height position of the respective plane is adjusted by at least one further height eleme

COMPACT ENDOSCOPE DESIGN FOR THREE-DIMENSIONAL SURGICAL GUIDANCE

Absstract of: US2025311915A1

The present invention is directed to endoscopic structure illumination to provide simple, inexpensive 3D endoscopic technique to conduct high resolution 3D imagery for use in surgical guidance system. The present invention is directed to an FPP endoscopic imaging setup which provides a wide field of view (FOV) that addresses a quantitative depth information and can be integrated with commercially available endoscopes to provide tissue profilometry. Furthermore, by adapting a flexible camera calibration method for the 3D reconstruction technique in free space, the present invention provides an optimal fringe pattern for the inner tissue profile capturing within the endoscopic view and validate the method using both static and dynamic samples that exhibits a depth of field (DOF) of approximately 20 mm and a relative accuracy of 0.1% using a customized printed calibration board. The presented designs enable flexibility in controlling the deviated angle necessary for single scope integration using FPP method.

AUTOMATED METHODS FOR DESIGNING AND FABRICATING AN INTRA-ORAL APPLIANCE

Absstract of: US2025312122A1

A method for designing a custom-made intra-oral appliance includes obtaining a virtual 3D reconstruction of an oral cavity, identifying an appliance region, obtaining a 3D appliance mesh from the appliance region, and processing the 3D appliance mesh for obtaining a volumetric appliance mesh. A method for obtaining a virtual 3D reconstruction of an oral cavity, the virtual 3D reconstruction being suitable for use in designing custom-made intra-oral appliances, and a method for designing an intra-oral appliance. The method for obtaining a virtual 3D reconstruction of an oral cavity includes obtaining at least one 2D image of an oral cavity, wherein the at least one image is acquired by a consumer electronics product, transforming the obtained at least one 2D image into an initial virtual 3D reconstruction of the oral cavity, and transferring information included in a further virtual 3D reconstruction to the initial virtual 3D reconstruction.

DENTAL IMPLANTS

Absstract of: US2025312130A1

The present teachings relate to an assembled dental implant comprising a metallic body manufactured at least partially via an additive manufacturing process: wherein the body is provided with a cavity having an opening on one end of the body. and an inlay part at least partly introduced within the cavity and scalably connected with the metallic body thereby sealing-off the cavity. The present teachings also relate to the metallic dental implant body and manufacturing methods.

PATIENT-SPECIFIC HUMERAL HEAD GUIDE DEVICE AND SYSTEMS AND METHODS FOR MANUFACTURING SAME

Absstract of: US2025312048A1

A patient-specific humeral head guide device may be designed and manufactured to contour the shape of the humeral head of the patient, as determined from the medical images. For example, a system may generate computer-assisted manufacturing (CAM) instructions based on one or more medical images of the shoulder of the patient. The CAM instructions may include G-code that causes a three-dimensional (3D) printer to manufacture a patient-specific humeral head guide device. The system may generate G-code for other various portions of the patient-specific humeral head guide device. For example, the system may generate instructions for manufacturing a patient-specific humeral head guide device to include a footprint (including a body and an extended footprint) that contours the humeral head, a plurality of fixation wire channels (for drilling to receive a respective fixation wire), a reaming channel, a resection channel (for cutting), and/or other portions described herein.

COMPOSITE POSITIVE AND NEGATIVE POISSON’S RATIO TISSUE ADHESIVES

Absstract of: US2025312511A1

Some tissue adhesives include a solid having bio-absorbable fibers and at least one of nano-spheres, micro-spheres, nano-tubules, or micro-tubules. A first layer of the solid has a positive Poisson's ratio and a second layer of the solid has a negative Poisson's ratio. In some cases, the second layer has been transformed from a positive Poisson's ratio material to a negative Poisson's ratio material. In some cases, an entire face of the first layer is in contact with an entire face of the second layer. In some cases, the second layer includes one or more pores, at least a portion of the one or more pores containing a secretion from one or more barnacles. In some cases, the secretion is configured to adhere the tissue adhesive to one or more layers of tissue to at least partially close a wound.

BONE INSERT AUGMENT AND OFFSET METHOD

Nº publicación: US2025312068A1 09/10/2025

Applicant:

TAQ ORTHO LLC [US]
Taq Ortho, LLC

Absstract of: US2025312068A1

A bone insert includes a cap having a convex top surface, an elongated stem, and a barrier between the cap and the stem. The stem of the bone insert is inserted into a hole formed in a host bone until the barrier is pressed against the exposed bone. The bone implant can be placed against a small focus contact point on the cap. Liquid cement can be injected into a space volume between the host bone and a bone implant. The cap can be made of a material and/or have surface features that create a strong bond with the cement when the liquid cement cures. The stem can be made of a material and/or have bone ingrowth surface features that create a strong bond with the bone.