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166
results.
Updated on
18/03/2026 [07:21:00]
Absstract of: CN121668399A
本发明公开了一种电场辅助3D打印制备含电气石颗粒的同轴骨支架的方法，包括：步骤1、制备外壳浆料和内芯浆料；步骤2、搭建电场辅助的同轴3D打印设备；步骤3、打印同轴骨支架。本发明将同轴3D打印技术与静电场技术相结合，通过同轴加料口和环形电极的设计，制备了具有粘度梯度的同轴支架，内芯为高粘度浆料容易凝固成型，提供良好的力学支撑；外壳为含电气石颗粒的低粘度浆料，能在环形电极形成的静电场的作用下使电气石颗粒在支架表面定向排列。
Absstract of: CN121673466A
本发明涉及一种用于3D打印的高内相双峰乳液及其制备方法和应用，所述制备方法包括如下步骤：将第一高内相乳液和第二高内相乳液进行剪切搅拌混合，得到所述用于3D打印的高内相双峰乳液；所述第一高内相乳液的众数粒径大于第二高内相乳液的众数粒径。本发明提供的用于3D打印的高内相双峰乳液具有自稳定性，进行3D打印的结构稳定好，精度高，不易出现结构坍塌、变形、分层和脱落等问题。
Absstract of: CN121668051A
本发明公开了一种用于治疗口呼吸的个性化3D打印水凝胶贴片及其制备方法，涉及3D打印水凝胶贴制备技术领域，包括获取使用者唇部区域的三维表面形貌数据，并基于该数据构建个性化水凝胶贴片的数字模型；根据数字模型设计具有唇周贴合轮廓的三维结构文件；配制包含明胶甲基丙烯酰化、多巴胺甲基丙烯酰胺、丙烯酰胺、聚乙二醇二丙烯酸酯、光引发剂及护肤型功能性添加剂的预聚物溶液；将预聚物溶液注入光固化3D打印设备，并调用三维结构文件进行逐层曝光打印，形成湿态水凝胶贴片；将湿态水凝胶贴片置于缓冲溶液中清洗，以去除未反应组分；对清洗后的水凝胶贴片进行后固化处理，使交联网络充分形成，获得具备适中黏附力与高韧性的成品贴片。
Absstract of: CN121668395A
本申请提供了提供了一种抑菌水凝胶人造皮肤及其制备方法，属于3D打印生物材料技术领域，按重量份数计，包括以下原料制备得到：六水合氯化铝1～3份、水30～45份、接枝改性壳聚糖15～22份、丙烯酰胺8～15份、N,N'‑亚甲基双丙烯酰胺0.2～0.8份、光引发剂0.5～1.5份、季铵化壳聚糖6～12份和纳米羟基磷灰石4～8份。其中，接枝改性壳聚糖包括以下原料制备而成：壳聚糖5～10份，浓度2%乙酸溶液80～120份、甲基丙烯酸缩水甘油酯0.8～2.5份和偶氮二异丁腈0.05～0.2份。本申请通过采用以接枝改性壳聚糖为核心的配方，形成多尺度交联和个性化3D打印的协同设计，实现水凝胶的高力学强度、广谱长效抑菌、精准形态适配与优异生物相容性，满足临床复杂创面修复需求。
Absstract of: CN121668390A
本发明提供了一种医用纤维增强复合材料的制备方法，属于医用材料技术领域。本发明提供一种兼具高屈服强度和弹性模量，且孔隙率大的医用纤维增强复合线材的制备方法，进一步可通过3D打印得到医用材料，提高力学性能的同时，提高材料的孔隙率，孔道结构也有利于营养液输送，显著提高支架结构的生物活性，且制备方法简便，满足多种医疗器械应用需求。
Absstract of: CN121673045A
本发明公开了一种陶瓷内窥镜抓钳钳头的一体化成型方法。方法以氧化锆模型墨水与水溶性支撑墨水为原料，通过材料喷射成型逐层构建含上钳口、下钳口、旋转轴、连接管及螺纹鞘头的整体生坯；在齿形咬合区、镂空键槽及活动间隙按特定比例混合填充支撑，并在每2‑5层后采用螺旋滚刀在线铣削，保证尺寸精度。生坯经水洗、干燥、1550℃烧结后，制得致密度≥99.9%、Ra 3‑4μm、抗弯强度≥800MPa的陶瓷钳头，无需后续机加工或铆接。产品闭合宽度≤10mm，总长≤50mm，鳄鱼形弧面与32齿R0.1mm倒角协同镂空键槽、椭圆排液孔，实现轻量化、低损伤、高夹持力，可顺利通过φ2.0mm内镜通道，满足一次性使用需求，解决不锈钢钳头加工难、易过敏、易疲劳及成本高的问题。
Absstract of: CN121671003A
本发明涉及一种硅胶阻鼾器制造方法，属于医疗产品技术领域。该方法包括以下步骤：S1、数据获取与建模；S2、配准：将三维牙颌模型与头颅侧位片配准，实现牙颌模型与气道软组织的空间对齐；S3、测量分析：测量气道间隙、舌体形态及颌骨位置参数；S4、个性化矫正：根据测量结果自动设定下颌骨的前伸量与垂直打开量，依据WALA嵴与FA点设计牙弓扩弓宽度，设计舌诱导屏斜面角度以引导舌体向前向上移动；S5、制造。本发明突破传统阻鼾器仅能单一前移下颌的局限，通过协同调控下颌骨三维位姿、牙弓宽度及舌体姿态，实现对气道长度、宽度和高度的立体化综合扩展，有效增大气道容积，改善通气效率，显著提升对OSAHS的矫治效果。
Absstract of: CN121668406A
本发明涉及一种模拟天然软骨四层结构的组织工程关节软骨及其原位3D打印方法，通过精准的分层建模与层特异性生物墨水，复刻天然软骨“表层‑移行层‑辐射层‑钙化层”的结构与成分特征，依托优化的原位3D打印工艺，在关节腔内直接构建与缺损区解剖匹配、与天然软骨力学及生理功能一致的组织工程软骨。另外，本发明减少了BMSCs体外诱导分化步骤，降低细胞突变风险，同时提升修复组织与宿主软骨的长期整合性，解决了临床修复长期有效性不足的问题。
Absstract of: CN121647835A
本发明公开了儿童咬合垫、基于适应性咬合的儿童咬合矫治系统及其设计方法，儿童咬合垫包括两个本体，两个本体被配置为覆盖佩戴者上颌/下颌左侧后牙区和右侧后牙区，两个本体之间通过连接部连接；本体包括朝向对颌牙列的咬合面、以及朝向其所覆盖牙列的组织面；组织面形成有用于容纳目标牙齿的萌出窝；萌出窝由侧壁和与目标牙齿咬合面相适配的窝底壁限定而成，侧壁围绕一引导轴线延伸；其中，本体被配置为在佩戴状态下，引导轴线相对于佩戴者的腭平面垂线具有预设偏转角度，以通过引导轴线的方向引导目标牙齿的萌出；萌出窝的窝底壁具有沿引导轴线方向测量的预设厚度。本发明提供的儿童咬合矫治系统既能提高固位力，又能根据错��类型主动引导牙齿定向萌出、重塑功能咬合平面，从而通过消除下颌内旋/外旋机制来矫治颌骨畸形。
Absstract of: CN121648350A
本发明化学技术领域，具体涉及一种3D打印掺镁矿化胶原复合骨支架及其制备方法，复合骨支架主要由掺镁矿化胶原、羟基磷灰石和左旋聚乳酸制成，左旋聚乳酸、镁矿化胶原和羟基磷灰石质量比为3~5∶2~4∶1。制备方法，其步骤为：胶原蛋白溶解在酸性缓冲溶液中，滴加含PO43‑溶液后，再依次滴加含Ca2+与Mg2+的混合盐溶液，制得混合溶液；S13在混合溶液中加入碱溶液调节混合溶液pH至8.0~9.0，生成掺镁矿化胶原；将掺镁矿化胶原、左旋聚乳酸和羟基磷灰石混合后通过3D打印制成复合骨支架。本发明的制备方法，克服胶原不稳定的技术偏见，可以实现一步共沉淀法钙镁磷共沉积。
Absstract of: WO2021147336A1
A method for fabricating a shell-shaped dental instrument, comprising: obtaining a three-dimensional digital model of a shell-shaped dental instrument (101); inspecting the three-dimensional digital model of the shell-shaped dental instrument (103); according to the result of inspection, directly modifying the three-dimensional digital model of the shell-shaped dental instrument (105); and using 3D printing technology to make the shell-shaped dental instrument on the basis of the modified three-dimensional digital model of the shell-shaped dental instrument (107). The present method can overcome the limitations on various aspects of a shell-shaped dental instrument caused by the limitedness of the traditional hot pressing film forming process.
Absstract of: CN121647847A
本发明涉及蠕动器技术领域，且公开了一种用于深部脑神经定向再生的微型蠕动器，包括微型蠕动器，所述微型蠕动器的表面设置有褶皱结构，所述微型蠕动器的内部设置有驱动结构，所述驱动结构为记忆合金丝，通过电流控制记忆合金丝，实现收缩与断电恢复形变，进而驱动微型蠕动器产生蠕动运动。本发明中，微型蠕动器整体呈蠕虫状且由两个C形结构组成，配合表面连续环状褶皱结构，可模拟自然界生物在狭窄空间的高效蠕动模式，既能适配深部脑神经区域复杂的管腔与组织间隙，又能避免蠕动过程中对周围软组织的刮擦损伤，同时褶皱结构为运动提供稳定波形动力，确保在精细神经环境中灵活前行。
Absstract of: US2025018599A1
Process and slip for the production of ceramic shaped parts made of zirconium oxide ceramic by a 3D inkjet printing process. The slip contains zirconium oxide which is suspended in a liquid medium, wherein the slip has a zirconium oxide content of from 68 to 88 wt.-% and contains not more than 5 wt.-% organic components. The process for the production of ceramic components comprises the layered shaping and subsequent sintering of the desired component from the slip.
Absstract of: CN121648349A
本发明公开了一种功能化骨软骨修复材料，包括依次连接的软骨层、过渡层和骨层，所述软骨层以透明质酸、I型胶原蛋白和壳聚糖为基材，所述过渡层以羟基磷灰石和聚乳酸‑羟基乙酸共聚物为基材，所述骨层以β‑磷酸三钙、羟基磷灰石和聚乳酸‑羟基乙酸共聚物为基材，本发明涉及医用生物材料技术领域，通过设计有机‑无机复合过渡层，梯度衔接软骨层和骨层，界面剪切强度≥0.5MPa，有效解决了传统分层材料层间剥离的问题，能承受关节运动时的剪切应力和压缩应力，制备工艺采用冷冻干燥、模压成型、烧结等成熟医用材料生产设备，可实现规模化批量生产，同时支持选择性激光烧结3D打印的个性化制备，适配不同临床场景需求。
Absstract of: AU2025205378A1
21894047_1 (GHMatters) P119307.AU.2 The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- ing. The system comprises a 3D printing machine (2) with a me-5 chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3) and a base system (4) carrying a print base (6) for receiving a prepared mixture (27) applied by the print head (5). The system comprises at least one carrier (35) for 10 holding a cartridge (28).Printing can be done on formatted print locations (49) on the base (6). The invention further relates to a method for producing pharmaceutical objects, comprising the steps of providing at least one pharmaceutical substance in at least one cartridge, placing the cartridge in a carrier, estab-15 lishing a fluid connection between a cartridge and a print head, such that the pharmaceutical substance may leave the print head through the print head nozzle, moving the print head nozzle ac- cording to a 3D print program and dispensing the pharmaceutical substance to a print base. 20 (Fig. 24) The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- 5 ing. The system comprises a 3D printing machine (2) with a me- chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3)
Absstract of: WO2026054808A1
A system and method for planning and simulating a surgical operation to create a patient-specific spinal implant are disclosed. The system comprises a remote server configured to receive patient-specific medical image data and generate a 3D mesh model of the patient's spine using algorithms that separate vertebral bodies, remove artifacts, and smooth surfaces. A doctor's computer receives the 3D mesh model and allows real-time manipulation of intervertebral spaces to achieve a desired spinal curvature. The server generates a spinal implant design with surface-mapped endplates matching the patient's vertebral anatomy, which is transmitted to a 3D printer for manufacturing. The method includes steps of receiving image data, generating and updating the 3D mesh model based on doctor input, generating the final implant design, and transmitting it for production. The invention enables the creation of patient-specific spinal implants with improved conformity and surgical outcomes.
Absstract of: WO2026052280A1
The invention relates to a membrane (1) for a membrane contactor (2), which membrane is in the form of a hollow three-dimensional tube structure located on both sides of a plane/central plane (ME), in particular a hollow tube structure which is mirror-symmetrical to the plane/central plane and consists of branched tubes (3, 3 ́, 3 ́ ́, 3 ́ ́ ́, 3 ́ ́ ́ ́), preferably not exclusively planar branched tubes (3, 3 ́, 3 ́ ́, 3 ́ ́ ́, 3 ́ ́ ́ ́) having a plurality of branching planes (VE) in parallel with the plane/central plane (ME) on both sides of the plane/central plane (ME), wherein the walls of the tube structure are permeable to substances and/or permeable to energy, and wherein, in the region (B) of each branching plane (VE), each tube (3, 3 ́, 3 ́ ́, 3 ́ ́ ́) extending towards the plane/central plane (ME) branches into a plurality of tubes (3 ́, 3 ́ ́, 3 ́ ́ ́, 3 ́ ́ ́ ́) extending with respect to the plane/central plane (ME), and the tubes (3 ́ ́ ́ ́) extending from both sides of the plane/central plane (ME) from the corresponding last branching plane (VE) with respect to the plane/central plane (ME) merge into one another in the region (ÜB) of the plane/central plane (ME). The invention also relates to a membrane contactor (2) having a membrane of this type, and to a method for producing a hollow membrane (1).
Absstract of: WO2026054745A1
The invention relates to an anatomical below-knee prosthetic leg that can be fabricated with a 3D printer, which has a complex geometry optimised according to stress regions by means of structural analyses considering engineering calculations and various loading conditions in daily life with a topology optimization method, for below-knee amputee patients.
Absstract of: WO2026053002A2
In a bioprinting system and method, a bioprinter may include one or more reservoirs, a printhead, and a print surface on which the bioprinting is dispensed. An optical system may collect imaging data of a plurality of cells within a cross-linkable material during and/or after passage of the plurality of cells through the bioprinting system. A computing system may generate, via a machine learning algorithm executing on the image data, a plurality of segmented regions in the image data, wherein each segmented region in the plurality of segmented region defines a boundary around a different set of cell aggregates in the plurality of cells, identify a first segmented region in the plurality of segmented regions that defines a boundary around at least a visible portion of a first cell aggregate, wherein the first cell aggregate includes an occluded portion, determine, based on an estimated shape of the first cell aggregate, an extrapolated boundary around at least some of the visible portion of the first cell aggregate and at least some of the occluded portion of the first cell aggregate, compute a quantity of cells within the first cell aggregate based on an area surrounded by the extrapolated boundary, and determine one or more parameters associated with the plurality of cells, the material flow, or the bioprinting system based on the quantity of cells.
Absstract of: WO2026053003A2
In a bioprinting system and method, a bioprinter may include one or more reservoirs, a printhead, and a print surface on which the bioprinting is dispensed. An optical system may collect imaging data of a plurality of cells within a material flow while passing through and/or exiting from the bioprinting system, wherein the passage of the plurality of cells through the bioprinting system creates a printed fiberduring and/or after. A computing system may identify a first frame in the imaging data captured at time t-n and a second frame in the imaging data captured at time t, generating, via a machine learning algorithm executing on the imaging data, a plurality of segmented regions in the imaging data, wherein each segmented region in the plurality of segmented region defines a boundary around a different set of cell aggregates or cells in the plurality of cells, determining, for combining with the first frame and based on the plurality of segmented regions, a portion of the second frame that is substantially non-overlapping with the first frame, determining, based on the plurality of segmented regions, one or more cells or cell aggregates in the plurality of cells that are located along an edge of the first frame or an edge of the portion of the second frame, identifying a seam where the first frame and the portion of the second frame are to be combined based at least on locations of the one or more cells or cell aggregates, combining the first frame and the portion of the sec
Absstract of: WO2026053080A1
An anchor for use with an orthodontic appliance is provided. The anchor is configured to be coupled to an anchor surface defining a reference plane. The anchor includes a base configured to be coupled to the anchor surface, such that the reference plane interfaces with the base. The anchor further includes a hook portion extending from the base and curving towards the reference plane. The hook portion includes a tip distal to the base. The hook portion defines a pocket having a minimum width relative to the reference plane. A maximum distance between the tip and the reference plane is less than the minimum width of the pocket.
Absstract of: WO2026055711A1
A sternal implant for implant into a body is provided. The implant includes an outer frame forming a structurally rigid portion. The outer frame includes a plurality of openings configured to accommodate sutures for affixing the outer frame to the body. The implant includes a central structure connected within the outer frame. The central structure includes a in the form of a layer having a construction including multiple channels. The filling portion is configured to allow for fluid drainage and tissue ingrowth of tissue generated by the body.
Absstract of: DE102024126035A1
Die Erfindung betrifft ein Tibia-Implantat (2) für Gelenkersatz, welches aus Metalllegierung in einem additiven Fertigungsverfahrenhergestellt ist, mit einem Plateauabschnitt (4) und mit einem auf der tibiazugewandten Seite (8) des Plateauabschnitts (4) vorspringenden und sich davon in einer axialen Richtung (10) wegerstreckenden zapfen- oder kielförmigen Ankerabschnitt (6),; erfindungsgemäß wird vorgeschlagen, dass der Plateauabschnitt (4) auf seiner tibiazugewandten und mit Tibiaknochengewebe in Kontakt gelangenden Seite (8) eine dreidimensional poröse offenporige Oberflächenstruktur (14) mit in der axialen Richtung (10) hintergreifbaren Brücken, Stegen oder Wandbereichen aufweist, wobei die offenporige Oberflächenstruktur (14) eine erste Rauigkeit aufweist, und dass der Ankerabschnitt (6) anschließend an den Plateauabschnitt (4) in einem ersten axialen Ankerbereich (20) umfangsseitig eine in einer radialen Richtung (12) hinterschnittfreie, das heißt von hintergreifbaren Brücken und brückenbildenden Stegen freie Oberflächenstruktur (28) mit einer zweiten Rauigkeit aufweist, die geringer ist als die erste Rauigkeit, und dass der Ankerabschnitt (6) in der axialen Richtung (10) anschließend an den ersten axialen Ankerbereich (20) einen zweiten axial frei endenden axialen Ankerbereich (22) mit einer glatten Oberfläche aufweist.
Absstract of: US20260070777A1
The present disclosure provides a microstructured article including a thermoplastic polymer shaped to have a curve. At least a portion of the curve includes a microstructured surface of utilitarian discontinuities and the microstructured surface includes peak structures and adjacent valleys. The peak structures and the curve are formed of a single piece of the thermoplastic polymer. A method of making the microstructured articles is also provided including a) obtaining a tool shaped to include at least one of a protrusion or a concavity; b) disposing a microstructured film on at least a portion of the tool including the protrusion and/or the concavity; and c) thermoforming a single piece of thermoplastic polymer onto the tool to form a microstructured article shaped to include a curve. The curve is an inverse of the protrusion or the concavity of the tool.
Nº publicación: AU2026201217A1 12/03/2026
Applicant:
RESMED PTY LTD
ResMed Pty Ltd
Absstract of: AU2026201217A1
A patient interface comprises a support structure and a seal-forming structure. The support structure is arranged to support the sealing portion and is configured to connect to the frame. The sealing portion comprises textile and is attached to the support structure along an outer perimeter of the sealing portion such that in use the sealing portion may be in tension due to reactive stress of the support structure and/or a resilient stretch characteristic of the textile such that the sealing portion exerts a force against the patient’s face. eb e b
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