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187
results.
Updated on
07/05/2025 [07:43:00]
Results 25 to 50 of 187
Absstract of: AU2023371660A1
Provided herein are medical devices and methods for treating bone fractures. The medical device comprises a body with a proximal end and a distal tip, housing a scaffold with a porous structure distributed in proximal and distal lattices. The device includes an upper lumen in fluid communication with a first opening at the proximal end, and a lower lumen in fluid communication with a second opening at the proximal end. The device is configured to support independent delivery of cement and cells to the lattices. In some embodiments, the device is a bone screw with a thickened head-neck junction, designed to reduce the likelihood of rod breakage during installation. The methods involve implanting the device into a patient's bone, providing an innovative approach to fracture treatment.
Absstract of: AU2023365980A1
A melt electrowritten soft tissue scaffold, comprising: a first region having one or more sets of fibres and a second region having one or more sets of fibres; and an interface region joining the first region and the second region, the interface region being electrowritten along with the first and second regions in a continuous printing path, such that fibres in the interface region each join between a respective pair of fibres in the first and second regions.
Absstract of: US2025137271A1
An inventive articulating medical stand comprises a lower horizontal support member, a vertical support member, an upper horizontal support member, a tray mounting member and an adhesive medical tray member. The vertical support member is connected to the lower horizontal support member and is capable of vertical height adjustment, and optionally axial rotational adjustment. One end of the upper horizontal support member is connected to the vertical support member and is capable of axial rotational adjustment. The tray mounting member is slideably connected to the upper horizontal support member and is capable of linear adjustment along the longitudinal length of the upper horizontal support member. The tray mounting member is also capable of angular rotational adjustment with respect to the longitudinal axis of the upper horizontal support member. The adhesive medical tray member is removably connected to the tray mounting member and comprises a releasably adhesive component for attachment of medical items. Accordingly, the articulating medical stand is configured such that the adhesive medical tray member can be adjusted through all axes of dimension.
Absstract of: US2025135142A1
A nasal cannula cover comprising two cooperative portions which may be when not in use “snapped together” while one portion remains moveably affixed to the cannula and moveably stored just above “a plastic cuff” commonly used to tighten/loosen the cannula. In certain embodiments, the nasal cannula cover can be attached to a user's ears.
Absstract of: US2025135169A1
The invention relates to a patient-specific implant (5) for insertion into a body cavity of a patient, for example into the round window niche of the middle ear. The invention also relates to a method of manufacturing such an implant (5).
Absstract of: US2025136927A1
The invention relates to a composition for preparing a 3D scaffold for culturing cells and tissue, such as human cells and tissue. In particular embodiments, the present invention relates to a composition comprising a biocompatible polymer suitable for the preparation of a hydrogel, and a modified extracellular matrix (ECM) protein that is unreactive towards the biocompatible polymer, such that, after preparation of a hydrogel, the modified ECM protein is not covalently bound to the hydrogel. Compositions of the invention are suitable for use in 3D bioprinting, tissue engineering, drug screening, disease modelling and methods of treatment such as tissue regeneration.
Absstract of: US2025134636A1
The present invention relates to a plate denture production kit for stereolithography including a curable composition for a denture base (I) containing a (meth)acrylic based polymerizable monomer component (A) containing a (meth)acrylic based polymerizable monomer (m) as a major monomer, and a photopolymerization initiator, and a composition for a prosthetic tooth (II) containing a (meth)acrylic based polymerizable monomer component (B) containing the same (meth)acrylic based polymerizable monomer (m) as contained in the curable composition for a denture base (I), having a content of the (meth)acrylic based polymerizable monomer (m) of 20% by mass or more based on 100% by mass of the (meth)acrylic based polymerizable monomer component (B), and a method of producing a plate denture.
Absstract of: US2025135723A1
Microfluidic-based fiber formation methods and systems employ a computer vision and deep learning system and method to enable contactless sensing, analysis, and monitoring of key operational parameters within microfluidic crosslinking printheads on 3D bioprinters. Embodiments may employ object detection and/or semantic segmentation to facilitate the sensing, analysis, and monitoring. Deep learning can employ convolutional neural networks to localize and analyze the flow of different biological materials within the microchannels as well as to identify the operation of various microfluidic printhead on-chip components that can impact final quality of printed tissues. Printed tissues can include single-material fibers, including hollow filorezbers, as well as more complex coaxially-layered fibers.
Absstract of: US2025134642A1
A vascular implant including a tubular body of a polymeric material. The body has opposed filter body ends and a longitudinal axis. The body has a generally tubular segmented side wall that includes multiple spaced apart wall panels surrounding a central open-ended bore. The body includes one or more filtering elements in the bore and in between filter ends. One or more filtering elements including a hub at the central longitudinal axis and multiple radially extending filtering arms extend radially between the hub and wall, wherein each arm connects to a wall panel. The tubular body end has anchors that prevent migration and/or tilting.
Absstract of: WO2025089466A1
Provided are a method for manufacturing a small-diameter bioresorbable artificial blood vessel by using a discharge method, and a small-diameter bioresorbable artificial blood vessel manufactured thereby. The method comprises the steps of: discharging an artificial blood vessel using a bioresorbable material; physically crosslinking the discharged artificial blood vessel; and chemically crosslinking the physically crosslinked artificial blood vessel.
Absstract of: WO2025089876A1
The present invention relates to a technology for manufacturing an artificial blood vessel and, more specifically, to a technology for manufacturing an artificial blood vessel by a 3D printing technique using hydrogel ink. In addition, the purpose of the present invention is to provide a training artificial blood vessel manufacturing apparatus capable of manufacturing an artificial blood vessel having physical properties similar to those of an actual blood vessel by presenting extrusion and curing conditions of hydrogel ink optimized for a 3D printing technique for manufacturing the artificial blood vessel.
Absstract of: WO2025089835A1
The present invention relates to a hydrogel composition for 3D printing and a method for fabricating an artificial blood vessel, using same, the hydrogel composition comprising a granular hydrogel and a matrix hydrogel solution, wherein the matrix hydrogel solution includes an acrylamide-based compound, a compound containing at least two hydroxyl groups, a crosslinking agent, an initiator, and a solvent.
Absstract of: WO2025090560A1
Methods for selective matting of some, but not all, surfaces of a silicone article of manufacture are disclosed. By use of a silicone matting additive and manipulation of process variables, a silicone article of manufacture may be produced that comprises some surface areas that exhibit silicone's inherent tacky texture and other surface areas that exhibit a matted texture. In an exemplary embodiment, a silicone prosthetic liner may be produced where an interior surface is taky and an exterior surface is matted.
Absstract of: WO2025091008A1
Described herein are methods of use involving tissue mimicking compositions comprising hydrogel systems and at least one therapeutic agent
Absstract of: WO2025091000A1
Provided herein are biodegradable nanocomposite inks for 3D printing of radiopaque scaffolds. In particular, X-ray visible, radiopaque, and photocurable liquid polymer-ceramic inks are provided comprising a composite of metal oxide nanosheets and acrylated/methacrylated polydiolcitrate polymers.
Absstract of: WO2025090537A1
The present disclosure provides systems and methods for fabricating an orthodontic retainer comprising a retainer base. The methods may include obtaining a first digital model representing the palate and the upper teeth of a patient. The methods may include creating, based on the first digital model, a second digital model representing the retainer base and a third digital model representing a teeth shell, and creating, based on the second digital model and the third digital model, a fourth digital model representing the retainer base and the teeth shell that are connected via a connecting structure. The methods may include generating a printed assembly by printing the fourth digital model using a first curable resin material. The printed assembly may at least include the retainer base, the teeth shell, and the connecting structure. The methods may include post-processing the printed assembly to obtain the retainer base.
Absstract of: WO2025090024A1
A printable shape memory polymer composition for use in fabricating a 4D printed dental aligner is provided The composition comprises a first (meth)acrylate monomer, a second (meth)acrylate monomer which provides transient crosslinks to the printable shape memory polymer composition, one or more crosslinkers, and a photoinitiator, wherein the printable shape memory polymer composition is responsive to change in temperature at temperature Tg to become flexible, allowing the printable shape memory polymer composition to be shaped and reshaped at temperature Tg. A 4D printed dental aligner comprising the printable shape memory polymer composition is also disclosed.
Absstract of: US2024238078A1
Embodiments herein relate to an implant for insertion into a patient. The implant comprises a plurality of unit cells arranged to form a three-dimensional lattice structure, the three-dimensional structure comprising a resting volume of the implant. The plurality of unit cells are arranged to form a porous network of the three-dimensional structure, and wherein the three-dimensional structure is a reversibly compressible three-dimensional structure, wherein a bulk porosity of the three-dimensional structure of the implant is at least 50%. Also disclosed is a method of tissue reconstruction or tissue augmentation. The method comprises implanting into the body of a subject an implant of the disclosure.
Absstract of: WO2024069629A1
A 3D-printing support medium is provided herein, comprising hybrid calcium-alginate hydrogel particles and a dispersion medium, formulated by combining calcium-alginate and a soluble polymer distinct from alginate, and the dispersion medium contains a minimum of 2 mM gluconate. These hybrid hydrogel particles possess an average size ranging from 0.1 pm to 50 pm, with exceptional homogeneity characterized by a particle size distribution of less than 50% RSD, resulting in a substantially transparent medium to visible light. The support medium is provided in various forms, including drained particles and slurries with different volume ratios of hydrogel particles to the dispersion medium. The process of preparing this support medium involves forming, pulverizing, washing, and contacting the hybrid hydrogel particles with a gluconate solution, ensuring the presence of gluconate within the hydrogel matrix.
Absstract of: WO2024062369A1
Guide plate for the anatomical realignment of a plurality of fractured bone portions, comprising a back surface configured such as it can be distinctively coupled to the surface anatomy of the area of said plurality of fractured bone portions and characterized by a first plurality of holes placed on a first portion of the guide plate and a second plurality of holes placed on a second portion of the guide plate, wherein the first plurality of holes is misaligned with respect to the second plurality of holes.
Absstract of: WO2025088142A1
The invention relates to a method for volumetric additive manufacturing (VAM) using holography for 3D printing an object, and a corresponding VAM system. The method includes determining a composite hologram, and performing a phase and/or spatial light modulating of a coherent input beam, such as a laser, based on the composite hologram and directing the spatially and/or phase modulated beam towards the reconstruction space to generate a pixelated projection in the reconstruction space, the pixelated projection being applied for printing the 3D object, for example using a photocurable resin. The invention provides improved resolution, speed, and/or light efficiency, in particular with respect to 3D printing of biological/medical objects, such as biocompatible implants, such as organs or parts of organs.
Absstract of: AU2023346376A1
The disclosure encompasses systems, compositions, and methods for use in vivo, including for reinforcement of soft tissue in an individual. The systems, compositions, and methods may utilize three-dimensionally printed scaffolds comprising at least a polymer scaffold and an extracellular matrix component(s), including comprised on the scaffold. The polymer scaffold may comprise particular unit cell structures of a specific design and patterns of alternating configurations of the unit cell structures.
Absstract of: WO2025087952A1
The present invention relates to a biofabrication system for bioprinting and/or patterning three dimensional scaffold and retention structures using biofilm producing bacteria as the means of synthesizing geometries. The machine comprises a negative mobile mold of the final three dimensional shape desired and one or more oxygen blocking floaters to allow biofilm growth only in the positive part of the aforementioned mold. The bioprinter movement is calibrated relative to the culture medium surface level to maintain continuous biofilm growth. The bioreactor may be used along with the ability to control temperature, humidity, air flow and culture media conditions and nutrients as the three dimensional synthesis requires.
Absstract of: WO2025088134A1
The present invention relates to a dental abutment and assembly for anchoring a dental appliance comprising means addressing, by allowing lateral and angular movements, deviation from tolerance generated at an interface between the dental abutment and a dental appliance produced by additive or subtractive manufacturing.
Nº publicación: JP2025513883A 30/04/2025
Applicant:
アプレシア・ファーマスーティカルズ・エルエルシー
Absstract of: MX2024012594A
A process system and method for the making of articles, using an omnidirectional magnetic movement system (20) with a transport surface and fabrication modules having a formation surface that can be transported omnidirectionally over the transport surface under the control of a movement controller. An article forming system provides process unit operations for forming articles onto the formation surface as the fabrication modules are moved asynchronously between a plurality of processing positions on the transport surface, and features a depositing device (40) for placing a construction material onto the formation surface and one or more processing devices (50,60) to form the construction material into the article.
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