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175
results.
Updated on
29/08/2025 [07:12:00]
Results 25 to 50 of 175
Absstract of: CN120531540A
本发明涉及一种熔融沉积3D打印的医疗支具，用于医疗的器具，它公开了在医疗支具的全封闭的镂空区域、半封闭的镂空区域、底座承托的镂空区域内都填充有支撑薄片，使医疗支具与支撑薄片一体成形，在医疗支具的非镂空区域阵列设置有水滴形状的通孔。本发明的优点是它能满足医疗支具3D打印支撑需求的同时，后期拆除容易，而且支撑薄片拆除对支具表面质量影响小，确保复杂结构的医疗支具与支撑薄片一体成型，使医疗支具内外表面及整体曲面造型质量更加高。
Absstract of: AU2023365980A1
A melt electrowritten soft tissue scaffold, comprising: a first region having one or more sets of fibres and a second region having one or more sets of fibres; and an interface region joining the first region and the second region, the interface region being electrowritten along with the first and second regions in a continuous printing path, such that fibres in the interface region each join between a respective pair of fibres in the first and second regions.
Absstract of: WO2024172411A1
The purpose of the present disclosure is to provide a patient-customized helmet and a control method therefor, the helmet enabling the injection of an ultrasound contrast agent (e.g., microbubbles) into blood vessels of a patient and the radiation of ultrasonic waves into the brain by means of an ultrasound module to open the blood-brain barrier and deliver a brain disease therapeutic agent to the affected area.
Absstract of: CN120514526A
本发明提供了一种基于3D打印技术的颈部理疗护具，属于医疗器械领域，所述护具由如下的部件组成：后颈托壳体、护具内衬、双震动马达、温控加热装置以及操作控制模块。所述后颈托壳体选用PLA可降解线材，创新性地融合3D打印技术与按摩理疗功能，为颈部健康护理带来全新解决方案。护具整体通过3D打印成型，能够依据个体颈部的精准扫颈部理疗护具则提升与皮肤接触的舒适度，并适应颈部日常活动。本颈部理疗护具在颈部保健、慢性颈部疾病辅助治疗以及颈部疲劳缓解等方面具有显著优势，为用户提供便捷、高效、个性化的颈部护理服务，具有广阔的市场应用前景。
Absstract of: CN120514920A
本发明公开了一种负载镁锰掺杂空位氧化铋的生物墨水及其制备方法、生物打印支架和应用，该生物墨水包括以下质量体积百分比（mg/mL）的组分：5%~15%的苯硼酸接枝甲基丙烯酰化明胶、1%~10%的聚乙烯醇、0.15%~0.3%的苯基(2,4,6‑三甲基苯甲酰基)磷酸锂、0.01%~1%的负载镁锰掺杂空位氧化铋，该生物墨水通过3D打印制备生物打印支架。本发明利用苯硼酸接枝甲基丙烯酰化明胶和聚乙烯醇为基础生物墨水材料，同时负载镁锰掺杂空位氧化铋，由其制备的生物打印支架具有良好的生物学功能，可以作为老年性骨缺损修复的骨植入物，具有重要的临床应用价值。
Absstract of: WO2024133585A1
The present invention provides a nebuliser (100) comprising one or more inputs (110), and a plurality of droplet ejectors (126) in fluid communication with the one or more inputs (110). Each droplet ejector comprises a nozzle portion and a piezoelectric actuator. The one or more inputs are for receiving one or more liquids. Each nozzle portion defines a nozzle outlet in fluid communication with the one or more inputs. Each piezoelectric actuator is operable to cause ejection of a liquid received by one of the one or more inputs through the respective nozzle outlet as one or more droplets to thereby generate an aerosol comprising the one or more droplets ejected by each droplet ejector.
Absstract of: CN120514917A
本发明涉及基于埃洛石纳米管的载药海藻酸钠水凝胶抗菌支架、制备方法及其应用，属于材料合成和生物医药技术领域。所述支架是由载药埃洛石纳米管、海藻酸钠和甲基纤维素混合依次经3D打印、交联后得到的具有一定孔隙率和孔径结构的支架，载药埃洛石纳米管包埋在海藻酸钠/甲基纤维素水凝胶，载药埃洛石纳米管是由聚乙烯亚胺修饰的埃洛石纳米管与带负电的广谱抗菌剂混合得到的。该支架兼具降解速率可控和生物相容性特点，适用于骨髓炎清创后的局部抗感染与骨再生治疗。
Absstract of: US2025262077A1
A three-dimensional subtractive manufacturing system configured for constructing an orthopedic orthosis from a first blank of a plurality of blanks includes a scanner configured to capture a 3D model of a body part of a patient, a central processor configured to receive the 3D model and select the first blank based on the three-dimensional model and a computer numerical control machine configured to receive the computer numeric control programming file and an identification of the first blank from the central processor. The central processor is configured to convert the 3D model into a CNC programming file. The CNC machine comprised of a subtractive manufacturing machine. The CNC machine configured to remove material from the first blank to form the orthopedic orthosis.
Absstract of: WO2025174829A1
A surgical tool kit and a method of installing a tissue, the method comprising positioning an alignment guide to ensure proper alignment of surgical tools relative to a lesion in a host tissue; inserting a guide pin into the host tissue to provide a reference point; using a punch to score the host tissue at the location of the guide pin; utilizing a cannulated reamer to prepare a socket in the host tissue; evaluating the prepared socket in the host tissue with a trial implant to ensure proper fit and alignment; employing an undercut tool to prepare at least one groove in the host tissue; and placing the tissue scaffold into the prepared socket using an insertion tool.
Absstract of: WO2025175303A1
A method according to the disclosure herein includes producing, via additive manufacturing, a first mold portion having a first recess based on a tooth portion of a patient mouth; producing, via additive manufacturing, a second mold portion having a second recess based on a gum portion of the patient mouth; positioning at least one artificial tooth in the first recess; aligning the first mold portion with the second mold portion to form a mold assembly having a cavity defined by the first recess and the second recess; filling the cavity with a resin; and removing a partial denture from the mold, the partial denture formed by the resin and the at least one artificial tooth.
Absstract of: US2025262031A1
Modular dental devices and methods of forming the same. The dental devices may include a first region having a first joining surface and a second region having a second joining surface. The first joining surface may have one or more protrusions and the second joining surface may include one or more corresponding features configured to mate with the one or more protrusions. The first and second regions may be coupled together at the first and second joining surfaces, where the one or more protrusions of the first joining surface mate with the corresponding features of the second joining surface to align the first region with the second region and to interlock the first and second regions.
Absstract of: US2025262033A1
A socket preparation tool configured to facilitate autotransplantation of a donor tooth to a recipient site is provided. The socket preparation tool includes a tooth replica of the donor tooth. A coronal portion is optionally included for facilitating alignment of the tooth replica adjacent teeth during a simulated autotransplantation. A radicular portion includes a smooth surface configured to facilitate compression of soft bone or soft tissue of the tooth replica or a contoured surface adapted for filing or cutting bone of the tooth replica. A cylindrical attachment is configured to be coupled to the tooth replica, such as via a receiver. A method of guided autotransplantation of a donor tooth via the customized socket preparation tool includes at least fitting and adjusting the socket preparation tool coupled to the tooth replica in the recipient site, before extracting the donor tooth.
Absstract of: US2025262036A1
A method according to the disclosure herein includes producing, via additive manufacturing, a first mold portion having a first recess based on a tooth portion of a patient mouth; producing, via additive manufacturing, a second mold portion having a second recess based on a gum portion of the patient mouth; positioning at least one artificial tooth in the first recess; aligning the first mold portion with the second mold portion to form a mold assembly having a cavity defined by the first recess and the second recess; filling the cavity with a resin; and removing a partial denture from the mold, the partial denture formed by the resin and the at least one artificial tooth.
Absstract of: AU2024218051A1
The present invention provides a curable composition for three-dimensional stereolithography, the curable composition being used in a vat photopolymerization method and containing 100 parts by mass of a polymerizable monomer component (A), 40 parts by mass to 400 parts by mass of an inorganic filler (B) that is composed of a single kind or plural kinds of inorganic particulate matter, and 0.01 part by mass to 5 parts by mass of a photopolymerization initiator (C), wherein: 80% or more of all primary particles that constitute the inorganic filler (B) have a particle diameter of 0.05 µm to 5.0 µm; and a sample, which is formed of this curable composition for three-dimensional stereolithography and has a thickness of 0.5 mm, has a transmittance of 1.00% to 50.00% with respect to activation light. The present invention also provides a method for producing this curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic model and a method for producing a dental restoration, each using this curable composition for three-dimensional stereolithography.
Absstract of: US2025262356A1
A method for treating a bone defect extending between a proximal bone structure and a distal bone structure of a patient may include resecting a region of bone between the proximal bone structure and the distal bone structure and encompassing the bone defect, positioning a biodegradable osteogenic scaffold within a biodegradable sleeve, coupling the biodegradable sleeve to a fixation member, positioning the biodegradable sleeve between the proximal bone structure and the distal bone structure, and attaching the fixation member to each of the proximal bone structure and the distal bone structure.
Absstract of: US2025262349A1
A biomaterial is provided. The biomaterial includes a methacrylated polymer-silver-containing bioactive glass (methacrylated polymer-AgBaG) in which the AgBaG is chemically coupled to the methacrylated polymer. The methacrylated polymer may include gelatin methacryloyl (GelMA). Methods of making and using the biomaterial are also provided.
Absstract of: US2025262348A1
A polymeric scaffold for bone repair and regeneration includes a body comprising a biodegradable polymer matrix and nanoparticles dispersed in the biodegradable polymer matrix, and a polydopamine surface coating on the body. A method of forming a composite scaffold for bone tissue engineering includes preparing a solution comprising a biodegradable polymer and a plurality of nanoparticles in a solvent, applying the solution to a surface of a mold and drying the solution to form a polymer matrix having nanoparticles dispersed therein, removing the mold from the polymer matrix to form an intermediate scaffold, and applying a polydopamine coating to the intermediate scaffold to form the composite scaffold.
Absstract of: US2025262351A1
A composition comprising decellularized extracellular matrices, hydrogels comprising the same, and methods of making the same are disclosed.
Absstract of: US2025262164A1
The present disclosure, in some aspects, is directed to methods of designing an oral drug dosage form formulated and configured to have a desired pharmacokinetic profile. In other aspects, the present disclosure is directed to oral drug dosage forms having a desired pharmacokinetic profile, and methods of making, such as three-dimensional printing, such oral drug dosage forms.
Absstract of: US2025265713A1
A method includes receiving a digital representation of an orthodontic aligner, analyzing the digital representation of the orthodontic aligner to identify a quality-related property of the orthodontic aligner, determining, based on the quality-related property, that the orthodontic aligner comprises a manufacturing flaw, and causing the orthodontic aligner to be remanufactured responsive to determining that the orthodontic aligner comprises the manufacturing flaw. Analyzing the digital representation includes comparing the digital representation of the orthodontic aligner with data based on a digital model of a dental arch associated with a stage of treatment to be performed using the orthodontic aligner, and calculating one or more differences between a feature determined from the data and a feature of the digital representation of the orthodontic aligner.
Absstract of: US2025262355A1
Described are methods for producing tissue constructs, tissue constructs produced by the methods, and their use. The described method of producing a tissue construct comprises providing a granular tissue, depositing one or more filaments on or in the granular tissue, each filament comprising an ink, and gelling or fusing the granular tissue, thereby producing the tissue construct.
Absstract of: AU2023361612A1
The invention relates to nerve conduits for connecting a lesioned nerve end to a target site. In particular, the invention relates to nerve conduits supporting repair of a nerve lesion and motor control and/or reducing risk of the development of a neuroma at the lesioned nerve end. Accordingly, a nerve conduit (10) for connecting a lesioned nerve end (26) to a target site (28) is suggested, comprising an elongate body (12) formed by a wall (22) and comprising a central portion (14) defining an inner cavity (16) and end portions (18, 19) defining a respective opening (20, 20') to the inner cavity (16) and arranged adjacent to the central portion (14) and at longitudinally opposing ends of the elongate body (12). One end portion (18) is configured as an insertion portion configured for inserting a respective nerve end (26). According to the invention, the other end portion is configured as a nerve end outlet portion (19), wherein an outer diameter of the wall defining the outlet portion (19) is larger than an outer diameter of the wall defining the central portion (14).
Absstract of: CN120051256A
A dental appliance for a patient includes a body including a first surface and a second surface opposite the first surface. The second surface defines a channel for receiving a plurality of teeth of the patient. The dental appliance also includes an arrangement of a plurality of features disposed on the first surface of the body. Each feature of the plurality of features includes a protrusion extending from the first surface opposite the second surface; a recess extending partially from the first surface toward the second surface; or a via extending from the first surface to the second surface. The arrangement of the plurality of features encodes feature data representing dental appliance information of the dental appliance or patient information of the patient.
Absstract of: US2025215166A1
This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel size. Particles can be repeatedly dehydrated and rehydrated in accordance to their environment, allowing for the storage of particles in a non-solvent such as ethanol. Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid at shear stresses that are below a critical value. Upon reaching the critical shear stress, the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The rheological behavior of these slurries can be adjusted by changing the compaction processes such as centrifugation force to alter the yield-stress. The narrower distribution and reduced size of these particles allows for an increase in FRESH printing fidelity.
Nº publicación: EP4603053A1 20/08/2025
Applicant:
UNIV DEGLI STUDI DI FOGGIA [IT]
Universit\u00E0 degli Studi di Foggia
Absstract of: EP4603053A1
A removable orthodontic device, suitable to obtain complex orthodontic movements and made with CAD-CAM techniques and 3D printing, comprising an orthodontic member, made from a shape memory polymer, in turn comprising: a restraint portion of a dental arch; a connection portion which is apt to be in contact with a palatal surface and/or a lingual surface; and one or more female members positioned at said connection portion; the orthodontic device further comprises one or more temporary anchorage devices (TADs), acting as orthodontic screw, comprising a shank, a hollow upper end and a protruding head which is attached to said upper end by a respecting connection screw, said head implementing a male connection member and being made from a shape memory polymer as well; said female members of said orthodontic member and said one or more TADs being shaped as to cooperate with each other implementing an automatic pressure connection, whereby a reversible connection mechanism is implemented.
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