Alerta

FERROMAGNETIC SKIRT FOR A MEDICAL DEVICE

Absstract of: WO2024163373A1

An implantable medical device includes a wire frame, a cover, and a sensor. The wire frame is formed of struts and openings. The cover connects to the struts of the wire frame. The cover is fashioned from a fabric including a PET fabric made of PET yarn and a ferromagnetic material combined with the PET fabric. The PET yarn is made from a plurality of PET fibers. The sensor is positioned on the cover and connected to the wire frame. The cover shields the sensor from detuning effects of the wire frame.

HINGE MECHANISM FOR A KNEE ORTHOSIS, PROCEDURE FOR FITTING A HINGE MECHANISM, AND A KNEE ORTHOSIS

Absstract of: EP4643829A1

The invention is related to the technical field of orthopedic devices, in particular knee orthoses for supporting a knee joint, and more specifically of an orthopedic device with a hinge, wherein the movement of the device can be limited by means of the hinge and where the hinge of the device is formed via 3D printing so that a knee orthosis can be made to measure for the patient and where a minimum of different parts is required for the assembly of the knee brace. The invention also includes a method for installing such hinge mechanisms and a knee orthosis provided with such hinge mechanisms.

HYDROGEL COMPOSITION FOR 3D PRINTING, AND 3D PRINTING HYDROGEL PREPARED THEREFROM

Absstract of: EP4644440A1

The present invention relates to a hydrogel composition for 3D printing, and a 3D printing hydrogel formed using the same, hydrogel composition comprising an acrylamide-based compound, a hydrophilic thickener, an alkali compound and a solvent.

DENTAL IMPLANTS WITH CORONAL FEATURES AND SYSTEMS, DEVICES, AND METHODS FOR DESIGNING AND MANUFACTURING SAME

Absstract of: WO2024145635A2

Root-analog dental implants include one or more coronal grooves that are sized, shaped, and/or configured to correspond to a size, shape, and/or position of a bone crest for an extracted tooth a root-analog dental implant is designed and manufactured to replace. The coronal grooves may be configured to engage with bone of an alveolar socket to enhance engagement between the root-analog dental implant and the alveolar socket particularly for the time period following seating the root-analog dental implant within the socket site and prior to osseointegration of the root-analog dental implant with the alveolar socket. This promotes stability of the root-analog dental implant within the socket site immediately following insertion and thereafter, which may decrease movement of the root-analog dental implant within the socket site, decrease a likelihood of foreign material such as bacteria or food entering the socket site, and/or reduce a risk of implant failure and jawbone injury.

3D PRINTING COMPOSITION FOR BIOMATERIALS

Absstract of: EP4644125A2

A 3D printing resin composition for a biomaterial and method for 3D printing the composition, wherein the composition comprises:(i) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)_n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1,(ii) at least one photo-initiator, and(iii) at least one light blocker.

DEVICES AND METHODS FOR POST-PROCESSING ADDITIVE-MANUFACTURED WORKPIECES

Absstract of: WO2024141861A1

Post-processing devices for post-processing additive-manufactured workpieces and methods thereof are described. Sequential cleaning and post-curing under vacuum may be accomplished within a single device. The post-processing device (100, 200A, 400) comprises: a chamber (102, 202, 402) comprising an inlet (104, 204, 404) configured to be in communication with a vacuum source, and an electrical outlet configured to be in communication with a power source; a spinning platform (108, 208, 308, 408) for retaining a plurality of workpieces (222), a rotating drive apparatus (118, 218, 418) for rotating the spinning platform; a collection vat (116, 216, 416) surrounding the spinning platform; and one or more post-curing light source (120, 220, 420); wherein the spinning platform, the rotating drive apparatus, and the collection vat, are housed within the chamber.

LIQUID WITH PATTERN AND PRODUCTION METHOD FOR SAME

Absstract of: EP4643651A1

The present invention aims to provide a pattern-containing liquid that contains, in a liquid matrix, a pattern that can provide color, taste, or tactile sensations such as mouthfeel and texture, and that has good stability, as well as a method for producing a pattern-containing liquid capable of stably forming the above pattern in a liquid matrix. The present invention relates to, for example, a pattern-containing liquid containing a pattern formed from at least one of a microparticulate or a colorant in a liquid matrix, the liquid matrix being a pseudoplastic fluid and contained in a container.

ORTHODONTIC APPLIANCES AND METHODS OF MANUFACTURING

Absstract of: EP4643810A1

Orthodontic appliances are disclosed, comprising an integrally formed shell including a first shell part comprising one or more first cavities adapted to receive the first teeth of the patient, a second shell part comprising one or more second cavities adapted to receive the second teeth of the patient, and a modified active shell part connecting the first shell part and the second shell part, and wherein the modified active shell part comprises one or more active elements configured to apply forces to the first and/or the second shell part. The disclosure further relates to methods for manufacturing an orthodontic appliance, to computer-implemented methods for generating an input file for a 3D printer and to kits comprising series of consecutive shells.

一种骨修复材料的制备方法

Absstract of: CN120884739A

本发明公开了一种骨修复材料的制备方法，属于生物医用材料技术领域。本发明采用Solidworks构建支架模型，利用3D打印技术制备海藻酸钠/壳聚糖/矿化胶原支架，形成具有良好成骨性能的骨修复材料；材料中海藻酸钠、壳聚糖、矿化胶原的质量比：1∶0.2~0.6∶0.2。本发明使用3D打印技术来制备支架，同时选取不同的壳聚糖浓度，以获得一系列不同性能的支架；通过研究发现，当打印墨水中壳聚糖浓度为0.01~0.03g/mL时，海藻酸钠/壳聚糖/矿化胶原打印墨水在酸性交联环境下形成稳定的支架；支架的力学性能随着壳聚糖浓度的增加，呈现上升的趋势；支架的壳聚糖浓度越低且处于pH=7.2‑7.5的环境下胶原释放越快，释放量也越大。

用于牙齿矫正的透明矫治器及附件的设计方法

Absstract of: WO2024232571A1

A design method for a transparent orthodontic device and an attachment for orthodontics according to the present invention, which is devised in order to solve the technical problem as described above, is a method for designing an orthodontic device by using a computer. As a means for solving the technical problem, the method comprises: a step (S01) of designing a shape of an attachment attached to a surface of a tooth model; a step (S02) of designing an inner surface shape of a transparent orthodontic device to correspond to the shape of the attachment designed in step S01; and a step (S03) of printing the transparent orthodontic device by using a 3D printer, wherein the attachment comprises: two pressurizing surfaces (101) formed to face each other; two inclined surfaces (201) which are in contact with the two pressurizing surfaces (101) and are formed to be inclined while facing each other; an upper end surface (301) having corners, all of which are in contact with the two pressurizing surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) attached to a surface of a tooth.

一种4D打印仿生假肢及其制备方法与应用

Absstract of: CN120884406A

本发明涉及一种4D打印仿生假肢及其制备方法与应用，涉及医疗康复器械技术领域，该仿生假肢包括仿生骨架和柔性驱动单元；柔性驱动单元位于仿生骨架的关节活动部位，用于驱动仿生骨架的运动；仿生假肢采用4D打印一体化成型得到，仿生骨架采用形状记忆复合材料制得，柔性驱动单元采用水凝胶驱动材料制得；形状记忆复合材料包括质量之比为(80％～95％):(5％～20％)的形状记忆聚合物和增强材料；水凝胶驱动材料包括质量之比为(50％～80％):(20％～40％):(3％～15％)的温敏性聚合物基体、稳定剂和功能性填料。本发明的4D打印仿生假肢具有动态调整能力，能够满足残肢在不同情况下的变化需求的问题。

使用3D打印聚电解质结构作为反向牺牲模板创建用于再生医学的3D分级通道支架

Absstract of: WO2024151882A1

What is presented herein is a robust sacrificial strategy to create hierarchical and perfusable microchannel networks within versatile scaffolds via the combination of embedded 3D printing (EB3DP), tunable poly electrolyte complexes (PEC), and casting methods. The sacrificial templates of PEC filaments (diameter from 100 to 500 pm) with arbitrary 3D configurations can be fabricated by EB3DP and then incorporated into various castable matrices (e.g., hydrogels, organic solutions, meltable polymers, etc.). Rapid dissolution of PEC templates within a 2.00 M potassium bromide aqueous solution leads to the high-fidelity7 formation of interconnected channels for free mass exchange. Continuous cell proliferation and ECM deposition is seen as a result. Subcutaneous implantation of channeled silk fibroin (SF) scaffolds with a porosity of 76% could lead to tissue ingrowth as high as 53%. Both histological and immunofluorescence analyses demonstrate that such channeled scaffolds promoted cellularization, vascularization, and host integration along with immunoregulation.

一种制造正畸装置的系统和方法

Absstract of: WO2024199274A1

The present disclosure provides systems and methods for orthodontic appliance production. The methods may include determining a baseline thickness of an orthodontic appliance for orthodontically treating teeth of a target subject. The methods may include, for each local point on the teeth of the target subject, determining a movement path of the local point from an initial location of the local point to a target location of the local point. The methods may also include, for each local point on the teeth of the target subject, determining, based on the movement path and the baseline thickness, a target thickness of the orthodontic appliance corresponding to the local point. The methods may further include directing a three-dimensional (3D) printer to integrally produce, based on the target thickness of the orthodontic appliance at each local point, the orthodontic appliance.

生物基光固化聚氨酯丙烯酸酯树脂及其制备方法和应用

Absstract of: CN120888043A

本发明属于高分子材料技术领域，具体涉及一种生物基光固化聚氨酯丙烯酸酯树脂及其制备方法和应用。本发明的生物基光固化聚氨酯丙烯酸酯树脂的制备方法，包括以下步骤：(1)取催化剂、第一阻聚剂、第一丙烯酸羟基酯和衣康酸混合，在90‑120℃下搅拌反应6‑9h，得到反应产物，然后加入环氧大豆油，在90‑120℃下搅拌3‑5h，得到预聚物；(2)将步骤(1)得到的预聚物降至室温，逐滴加入第二丙烯酸羟基酯和二异氰酸酯，然后在30‑60℃下搅拌反应1.5‑4h，直至NCO红外峰值消失，即得。本发明的树脂生物基含量高，黏度适中，柔韧性好，硬度高，附着力强，光泽度高，气味小，储存稳定性好，适合应用于制备UV固化涂料、UV固化油墨、UV固化胶黏剂、3D打印材料、甲油胶。

一种3D打印的骨组织工程支架、制备方法及其应用

Absstract of: CN120860305A

本发明涉及一种3D打印的骨组织工程支架、制备方法及其应用，属于生物材料技术领域。该方法以可生物降解的PCL材料为基体，混合金属氧化物纳米颗粒，得到制备简单、功能性强的3D打印墨水，然后采用FDM技术制备PCL骨组织工程支架。所制备的支架成型性能优，能够保证打印质量和一致性；此外，该支架生物相容性好，展现出显著的促进干细胞增殖分化和抗菌抗氧化等能力。

一种心肌修复材料及其制备方法和应用

Absstract of: CN120860329A

本发明公开了一种心肌修复材料及其制备方法和应用。该心肌修复材料包含多个层叠的纤维层，纤维层由若干个交错的微米级纤维组成，并具有微米级孔隙；微米级纤维的表面粗糙度Ra不低于130 nm。该心肌修复材料利用自身结构特点促进M2型巨噬细胞极化并增强血管生成，无需负载外源性活性成分即可促进心肌修复，避免了使用外源性活性成分引发免疫排斥反应的问题。

骨再生屏障构件及制备系统

Absstract of: CN120859635A

本发明公开了一种骨再生屏障构件及制备系统，其中，一种骨再生屏障构件，包括：钉体，表面设有自攻螺纹；覆盖件，可拆卸连接在所述钉体上，所述覆盖件的尺寸和形状与患者口腔内的缺损区域形态相适配；所述钉体的内部设置有药物释放通道，所述药物释放通道设置有药物；所述钉体的外壁上设置有多个微孔，所述微孔连通外部与所述药物释放通道，以释放药物。由此，能够与缺损区域完美适配，配合单一的钉体固定，即可完成对覆盖件的安装，固定方式简单，且能够有效减少应力集中现象，同时还能够延长药物的释放时长，保证对患者的治疗效果。

官能化的重组细菌胶原样蛋白

Absstract of: WO2024188844A1

Recombinant bacterial collagen-like protein, preferably with an amino acid sequence that is at least ≥ 60% identical to the amino acid sequence of SEQ ID NO:1 wherein the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1, wherein the recombinant collagen-like protein is functionalized with at least one non-terminal alkene group. A bioink comprising the functionalized recombinant bacterial collagen-like protein, at least one solvent and at least one photoinitiator, a process for producing a hydrogel by crosslinking the functionalized recombinant bacterial protein or the bioink as well as the hydrogel obtained therefrom. Furthermore, a scaffold for tissue engineering comprising the hydrogel.

基于改性木竹纳米纤维素的自修复柔性传感器及其3D打印制备方法与应用

Absstract of: CN120865697A

本发明涉及基于改性木竹纳米纤维素的自修复柔性传感器及其3D打印制备方法与应用，属于柔性传感器技术领域。为解决现有柔性传感器灵敏度低、耐久性差以及无法自修复的问题，本发明提供了基于改性木竹纳米纤维素的自修复柔性传感器的3D打印制备方法：步骤一、制备改性木竹纳米纤维素；步骤二、制备3D打印浆料；步骤三、3D打印制备自修复柔性传感器。本发明柔性传感器具有多尺度导电网络结构，灵敏度和柔性应变响应能力好；动态二硫共价键的引入赋予材料可逆交联特性，受损后2.5小时内即可实现力学性能的高效恢复，具有较好的结构稳定性和抗疲劳性能。本发明以生物基木竹纳米纤维为原料，通过3D打印实现低成本、高精度的定制化制造。

一种负载锰铁普鲁士蓝类似物的磷酸钙双层结构的组织工程材料及其制备方法

Absstract of: CN120860326A

本发明公开了一种负载锰铁普鲁士蓝类似物的磷酸钙双层结构的组织工程材料，制备方法为：S1、采用基体陶瓷浆料通过光固化3D打印成型，得到具有多孔结构的陶瓷湿坯；S2、对陶瓷湿坯进行梯度烧结，得到多孔陶瓷预制体；S3、将纳米磷酸钙与分散剂充分混合得到纳米磷酸钙悬液，将多孔陶瓷预制体置于纳米磷酸钙悬液中浸泡，烘干，得到双层多孔陶瓷湿坯；S4、将双层多孔陶瓷湿坯快速烧结，得到双层增强生物陶瓷；S5、将双层增强生物陶瓷置于普鲁士蓝类似物‑磷酸钙悬液中浸泡，烘干，得到负载锰铁普鲁士蓝类似物的磷酸钙双层结构的组织工程材料。本发明的组织工程材料兼顾力学性能高，表面粗糙度大以及有效缓解炎症，提高骨诱导性能等多重功效。

3D打印可吸收骨塞及其制备方法

Absstract of: CN120860308A

本申请提供一种3D打印可吸收骨塞的制备方法，属于生物医用材料技术领域，其制备方法步骤如下：1、对聚己内酯颗粒进行干燥处理，使其含水率不高于0.5%；2、将干燥后的聚己内酯颗粒与羟基磷灰石按配比混合，获得均匀的复合材料混合物；3、将复合材料混合物加入颗粒式3D打印设备中，通过螺杆送料至喷嘴处进行熔融处理；4、按照预设的骨塞三维模型进行逐层堆叠三维打印成型，形成具有连通多孔结构的骨塞坯件；5、对骨塞坯件进行后处理，得到成型的可吸收骨塞。本申请采用聚己内酯这一具备生物降解能力的热塑性高分子材料，结合具备良好骨诱导性的羟基磷灰石，有助于构建可被生理环境逐步吸收替代的植入物基础。

Chirurgisches Schaftinstrument sowie Verfahren zum Herstellen eines chirurgischen Schaftsinstruments

Absstract of: DE102024111699A1

Die vorliegende Erfindung betrifft ein chirurgisches Schaftinstrument (1) mit mindestens einem in mindestens einer Achse (X) beweglichen Maulteil (30) durch welches ein bevorzugt zangen- oder scherenartiges Werkzeug in einem distalen Endbereich (9) gebildet wird, aufweisend ein erstes Teil (10) mit einem entlang einer Schaftachse (L) angeordneten ersten Schaftabschnitt (20), ein zweites Teil (40) mit einem entlang der Schaftachse (L) angeordneten zweiten Schaftabschnitt (50) und einem im distalen Endbereich (9) angeordneten zweiten Führungsmittel (42) und mindestens ein im distalen Endbereich (9) an dem ersten Teil (10) angeordnetes Maulteil (30), wobei das mindestens eine Maulteil (30) ein erstes Führungsmittel (32) aufweist und einstückig ist, wobei das erste Teil (10) und das zweite Teil (40) derart zusammengesetzt werden können, dass das erste Führungsmittel (32) und das zweite Führungsmittel (42) derart zusammenwirken, dass bei einem gegenseitigen Verschieben des ersten Schaftabschnitts (20) und des zweiten Schaftabschnitts (50), das mindestens eine Maulteil (30) um die mindestens eine Achse (X) ausgelenkt wird. Weiterhin betrifft die vorliegende Erfindung ein Verfahren zum Herstellen des chirurgischen Schaftinstruments (1).

METHOD FOR ESTABLISHING A CONNECTION BETWEEN A NUMBER OF INSERTED DENTAL IMPLANTS AND A PROSTHETIC BODY

Absstract of: WO2025223663A1

The aim of the invention is to devise a method for providing a connection between a number of inserted dental implants and a prosthetic body, which makes it particularly simple to establish a reliable and secure connection between the prosthetic body and the inserted implants. For this purpose, according to the invention, the prosthetic body is provided with a recess for each dental implant, said recess being associated with the dental implant and being suitable for accommodating a connecting element of the particular dental implant. Following the insertion of the dental implants into the jawbone of the patient, the intraoral data characteristic of the oral situation of the patient including the inserted dental implants is captured. Using this intraoral data, the geometric data defining the intermediate space formed by the connecting element and the associated recess when the prosthetic body is correctly placed is determined for the connecting element of the dental implant, and, using this data, an intermediate body is produced that fills the intermediate space.

METHOD FOR ESTABLISHING A CONNECTION BETWEEN AN INSERTED DENTAL IMPLANT AND A CROWN AND METHOD FOR THE PRODUCTION OF A CROWN

Absstract of: WO2025223664A1

The aim of the invention is to devise a method for providing a connection between an inserted dental implant and a crown, which makes it particularly simple to establish a reliable and secure connection between the crown and the inserted implant. For this purpose, according to the invention, the crown is provided with an associated recess suitable for accommodating a connecting element of the dental implant. Following the insertion of the dental implant into the jawbone of the patient, the intraoral data characteristic of the oral situation of the patient including the inserted dental implant is captured. Using this intraoral data, the geometric data defining the intermediate space formed by the connecting element and the associated recess when the crown is correctly placed is determined, and, using this data, an intermediate body is produced that fills the intermediate space.

METHOD FOR ESTABLISHING A CONNECTION BETWEEN A NUMBER OF INSERTED DENTAL IMPLANTS AND A PROSTHETIC BODY AND METHOD FOR THE PRODUCTION OF A PROSTHETIC BODY

Nº publicación: WO2025223689A1 30/10/2025

Applicant:

ZIPPRICH HOLGER [DE]
ZIPPRICH, Holger

Absstract of: WO2025223689A1

The aim of the invention is to devise a method for providing a connection between a number of inserted dental implants and a prosthetic body, which makes it particularly simple to establish a reliable and secure connection between the prosthetic body and the inserted implants. For this purpose, according to the invention, the prosthetic body is provided with a recess for each dental implant, said recess being associated with the dental implant and being suitable for accommodating a connecting element of the particular dental implant. Following the insertion of the dental implants into the jawbone of the patient, the intraoral data characteristic of the oral situation of the patient including the inserted dental implants is captured. Using this intraoral data, the geometric data defining the intermediate space formed by the connecting element and the associated recess when the prosthetic body is correctly placed is determined for the connecting element of the dental implant, and, using this data, an intermediate body is produced that fills the intermediate space.