Absstract of: US20260240459A1
0000 This invention relates to a low-cost portable multispectral detection method and device for early disease diagnosis. The device is based on a CMOS multispectral sensor chip and uses natural light or halogen lamps as the light source to non-invasively detect physiological parameters from the eyes, oral cavity, and/or skin of patients. The device captures reflected light data of different wavelengths using the multispectral chip and processes the data to generate image information, subsequently identifying the corresponding test areas. By processing the initial spectral information, the device provides accurate spectral data analysis to determine physiological parameters such as glucose etc., enabling early diagnosis of diseases such as diabetes, etc. It features real-time data analysis and wireless data transmission, offering a convenient solution for large-scale health monitoring and telemedicine.
Absstract of: US20260241102A1
0000 Disclosed herein are techniques related to automatic real-time meal detection. In some embodiments, the techniques involve obtaining a plurality of glucose concentration values and a plurality of plasma insulin concentration values. At least one of the plurality of glucose concentration values is obtained within a time range of a determination of a respective plasma insulin concentration value of the plurality of plasma insulin concentration values. The techniques further involve generating an output based on applying a meal detection model to the plurality of glucose concentration values and the plurality of plasma insulin concentration values and determining, based on the output, that a glucose concentration value of the plurality of glucose concentration values corresponds to an ongoing glycemic response to a meal.
Absstract of: US20260240467A1
0000 A method for compensating for a life-lengthening agent for a glucose sensor includes accessing first and second electrochemical impedance spectroscopy (EIS) values of at least one parameter based on first and second EIS procedures performed on EIS signals from a working electrode of the glucose sensor, calculating a change in the at least one parameter between the first and second EIS values, estimating a concentration of the agent based on the change in the at least one parameter, and calculating a model effect in response to the concentration. In a case where the model effect is not greater than the threshold, the method further includes adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode, and displaying the adjusted sensor glucose value.
Absstract of: US20260241109A1
0000 Systems, methods, and devices relate, generally, to autonomous dose injection. One or more examples relate to a durable insulin injection device. Such a durable dose injection device may include a chamber, a drive mechanism, a logic circuit, and an actuator. The chamber may be to receive a prefilled insulin cartridge. The drive mechanism may be to apply force to a plunger of a received prefilled insulin cartridge, the plunger arranged to move within the received cartridge responsive to force applied by the drive mechanism and thereby push fluid in the received cartridge toward an interface for dispensing fluid. The logic circuit may be to receive analyte data for the user and calculate a target amount of insulin to deliver to a user. The dose-ready confirmation actuator may be for the user to actuate to cause the delivery of insulin to the user. In one or more examples, the durable insulin injection device does not provide the user with an indication of the calculated target amount of insulin for non-zero calculated target amounts of insulin.
Absstract of: US20260242737A1
0000 A culture medium and a culture medium additive which can promote myogenic differentiation. The culture medium and a culture medium additive contain ergothioneine, ascorbic acid 2-glucoside, ascorbic acid, or a combination thereof. A kit, pharmaceutical composition, food, and drink may also promote myogenic differentiation.
Absstract of: US20260241096A1
0000 An infusion element for infusing a substance into a body of a person, comprising: a housing that is suitable for being attached to the skin of said person; an infusion means for infusing the substance into the body of said person, said infusion means being arranged on and/or protruding from the first surface of the housing; at least one sensor for sensing a characteristic of the person, said sensor being arranged on and/or protruding from the first surface of the housing; wherein in use of the infusion element the infusion means is arranged for infusing said substance at a first depth and said sensor is arranged for sensing the characteristic at a second, different depth. A system for regulating the concentration of glucose in the blood of a person comprising such an infusion element.
Absstract of: WO2026171056A1
Disclosed in the present application are a blood glucose assessment method, a user interface, and a related apparatus. The method involves two phases: a calibration phase and an assessment phase. In the calibration phase, physical sign data used for reflecting a physical condition of a user, and a blood glucose value can be acquired, and a personalized blood glucose assessment model applicable to the user is obtained on the basis of the physical sign data and the blood glucose value. Then, in the assessment phase, physical sign data of the user is acquired, and a blood glucose result of the user is assessed on the basis of the physical sign data and the blood glucose assessment model, wherein the blood glucose result can be used for indicating a blood glucose condition of the user. In the method, in the calibration phase, the model is determined on the basis of the physical sign data and the blood glucose value, which improves the accuracy of the model. Moreover, in the assessment phase, the blood glucose condition of the user can be assessed without acquiring the blood glucose value, so that the trouble of acquiring the blood glucose value is reduced, and the blood glucose result that is accurate and conforms to an actual condition of the user can be obtained.
Absstract of: US20260240457A1
Provided is a sensor applicator assembly for a blood glucose monitoring including a body-attachable unit including an upper frame and a lower frame that is disposed under the upper frame and has a surface attached to a body and an applicator within which the body-attachable unit is disposed. The upper frame includes a first area and a second area disposed under the first area and in contact with the lower frame. A perimeter of an outer peripheral surface of the second area is identical to a perimeter of an outer peripheral surface of the lower frame.
Absstract of: US20260241095A1
0000 An infusion system comprising: a device configured to deliver medication to a user through an infusion catheter, wherein the device includes a housing configured to receive the infusion catheter and to maintain the infusion catheter in the user after insertion; and a detachable activation mechanism for deploying the device for delivering medication to the user, wherein the detachable activation mechanism comprises a trigger and a retraction mechanism that includes an introducer needle for introducing the infusion catheter into the user, wherein the detachable activation mechanism is configured to releasably connect to the housing, wherein the detachable activation mechanism is configured to insert the infusion catheter into the user, automatically release the detachable activation mechanism from the housing responsive to activation of the trigger and automatically retract the introducer needle into the needle retraction assembly to shield the needle upon the automatic release of the detachable activation mechanism.
Absstract of: US20260240464A1
0000 A composition for blood glucose measurement includes a copolymer including three types of monomers having a hydrophobic group, a hydrophilic group, and a boronic acid moiety, and a conductive material mixed with the copolymer, thereby enabling volume changes in response to glucose to be converted into electrical signals. An electrochemical sensor for blood glucose measurement includes a working electrode that includes the composition.
Absstract of: EP4793962A1
0001 The invention discloses a method of locating a lost device in a diabetes management system, the diabetes management system comprises at least one wearable medical device; at least one personal management device and a secondary management device, at least one of the personal management device and the secondary management device is configured to control the wearable medical device, the personal management device and the secondary management device are communicative connection with each other; when either the personal management device or the secondary management device is determined as lost, the other device is used to locate the lost one, thereby enabling the user to retrieve it with ease.
Absstract of: KR20200036122A
The present invention relates to a body attachment unit for continuous blood glucose measurement. According to the present invention, a body attachment unit is manufactured in an assembled state in an applicator to minimize extra additional work so that the body attached unit can be attached to a body only by simply operating the applicator. In particular, the body attached unit can be simply and easily used without additional work of connecting an extra transmitter by having a wireless communication chip to communicate with an external terminal. Maintenance of the body attached unit can also be more easily performed. In addition, the body attached unit can be operated by the operation of a user once the body attached unit is attached to the body of the user, and an operation start time point can be adjusted to an appropriate time point as needed. Therefore, the body attached unit can be operated in a more stabilized state to measure blood glucose more accurately.
Absstract of: US20260232717A1
0000 The invention relates to a terminally heat-sterilized multi-chamber container for parenteral nutrition, comprising a first chamber containing a macronutrient formulation and a second chamber comprising a vitamin B12 formulation, wherein the vitamin B12 formulation (a) is essentially free from glucose, amino acids, vitamin B1, ascorbyl palmitate and/or vitamin C; and (b) stably comprises vitamin B12 for at least 6 months at a temperature of from 1° C. to 40° C. and/or for at least 24 months at a temperature of 25° C.
Absstract of: US20260232202A1
0000 A quick screening method is provided for assessing diabetic foot syndrome for a person. Both feet of the person are positioned onto a testing plate that blocks visible light and permits passage of near infrared (NIR). A multi-spectral camera device is used to simultaneously capture a thermal image and an NIR image of soles of the feet from a side of the testing plate opposite to the feet. The thermal image is aligned with and overlaid onto the NIR image, thereby obtaining an assessment image of the feet. Based on the assessment image, a determination is made regarding whether a temperature difference between a predetermined portion of one foot and a corresponding portion of the other foot exceeds 2.2° C. A potential case of diabetic foot syndrome is reported when the temperature difference exceeds 2.2° C.
Absstract of: US20260232736A1
Disclosed herein are methods of treating a subject having diabetes with a population of stem cell-derived islet cells and one or more immunosuppressive reagents, such as an anti-thymocyte globulin binding moiety. The subject may have received an organ transplant.
Absstract of: US20260231913A1
0000 Provided are: a cancer model animal in which a malignant tumor corresponding to a pathological image of human invasive cancer or metastasis has been formed or can be formed, despite the use of transplantation under the skin or into the abdominal cavity; and a method for producing the cancer model animal. One aspect of the present invention is: a cancer model animal in which tumor cells that grow in a culture medium containing L-glucose are transplanted under the skin or into the abdominal cavity; cancer model animal in which tumor cells, such as adenocarcinoma cells, that have been transplanted under the skin or into the abdominal cavity show metastasis; or a cancer model animal in which tumor cells, such as adenocarcinoma cells, that have been transplanted under the skin or into the abdominal cavity show anomaly of function of orthotopic cells.
Absstract of: US20260232901A1
A system for regulating the concentration of glucose in the blood of a person, comprising: a device for selectively supplying at least one and preferably two substances to said person; at least one and preferably two infusion sets connectable to said device; at least one sensor for measuring a glucose concentration in the blood of said person; a controller for controlling said device such that a certain amount of a said substance is supplied per time unit, wherein said controller is arranged to determine a slope of the measured glucose concentration and if said slope exceeds a first threshold value said controller is arranged to control the device to supply a pre-injection amount of said at least one substance, said pre-injection amount being a percentage of a maximum pre-injection amount, wherein said percentage is dependent on the determined slope.
Absstract of: US20260232892A1
A system for regulating the concentration of glucose in the blood of a person, comprising: a device for selectively supplying insulin and glucagon; at least two infusion sets; at least one sensor for measuring a glucose concentration in the blood of said person; and a controller for controlling said device such that a certain amount of insulin and glucagon is supplied per time unit, wherein said certain amount is chosen in accordance with the measured glucose concentration as prescribed by an insulin injection curve and a glucagon injection curve, wherein said controller is further arranged to determine if glucagon is supplied to said person in a chosen time frame, and wherein the controller is arranged to re-assess and optionally adjust the insulin injection curve based on the determination if glucagon is supplied to said person in said chosen time frame.
Absstract of: US20260232232A1
A method and apparatus for analyzing a blood glucose concentration, a device, a storage medium, and a computer program product. The method comprises: acquiring intensity sets corresponding to photoplethysmography pulse wave sets for a target object in a target time period, the intensity set comprising an average alternating-current intensity and an average direct-current intensity; performing curve fitting on the intensity sets to obtain a fitting coefficient and a fitting bias; comparing the fitting bias with a bias range corresponding to the target object, and when it is determined that the fitting bias is not within the bias range, adjusting the fitting bias to obtain an adjusted fitting bias; and performing, on the basis of the adjusted fitting bias, curve fitting on the intensity sets to obtain an adjusted fitting coefficient, and taking the adjusted fitting coefficient as the blood glucose concentration of the target object in the target time period.
Absstract of: US20260232230A1
0000 Various systems and methods are disclosed. One or more of the methods disclosed uses machine learning algorithms to predict biophysical responses from biophysical data, such as heart rate monitor data, food logs, or glucose measurements. Biophysical responses may include behavioral responses. Additional systems and methods extract nutritional information from food items by parsing strings containing names of food items.
Absstract of: US20260232213A1
0000 A pulsewave velocity detection device provides a photodiode capable of detecting light transmission between 600-700 nm and 880-940 nm and a light emitting diode capable of transmitting the same. An optical isolation spacer separates the photodiode and the LED. A main control chip provides processing of collected pulsewave velocity signal detection by measuring with the photodetector. A microcontroller thereby calculates local metabolic rate, blood flow volume, Hb concentration, oxygen saturation, and corrected blood glucose and correlates a corrected blood glucose value to the calculated local metabolic rate, blood flow volume, Hb concentration, and oxygen saturation. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
Absstract of: EP4789663A2
Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
Absstract of: US12702755B1
A system which provides closed loop insulin administration is disclosed. A closed loop insulin administration system which bases insulin administration on accurate glucose measurements may improve a patient's quality of life.
Absstract of: AU2025206886A1
The present disclosure provides cells that are competitive to cancer cells without starvation and exhaustion even in an environment in which glucose is depleted. More specifically, the present disclosure provides T cells with enhanced glucose uptake ability, wherein the T cells are modified such that the expression of glucose transporters in the T cells is regulated in response to changes in tumor microenvironmental conditions, and/or the T cells comprise a nucleic acid sequence encoding a glucose transporter operably linked to a tumor microenvironment sensing element that senses changes in tumor microenvironmental conditions.
Nº publicación: AU2025207075A1 06/08/2026
Applicant:
NAT CANCER CENTER
ARC THERAPIES INC
NATIONAL CANCER CENTER
ARC THERAPIES INC.
Absstract of: AU2025207075A1
The present disclosure provides cells that are competitive with respect to cancer cells, without experiencing starvation or exhaustion, even in glucose-depleted environments. Specifically, the present disclosure provides survivor T cells with enhanced glucose uptake capacity. The T cells are modified so as to express a glucose transporter and/or configured such that the expression of a glucose transporter is enhanced. Also provided are a cell population including such cells, a pharmaceutical composition, and a treatment method.