Alerta

SYSTEM AND METHOD FOR OPTIMAL MAGNETIC RESONANCE EXAM WITH RETROSPECTIVE REFORMATTING WORKFLOW THAT LEVERAGES INTEGRATED GUIDELINES

Resumen de: US20260259290A1

A method includes receiving at a protocol optimizer an electronic medical record for the subject, wherein the electronic medical record includes a scan order for scanning a region of interest of the subject for a patient specific clinical indication with a magnetic resonance scanner. The method also includes utilizing the protocol optimizer to automatically access one or more initial protocols specific to the patient specific clinical indication from radiology guidelines and/or a protocol library. The method further includes generating with the protocol optimizer one or more optimized protocols from the one or more initial protocols for performing an acquisition including a three-dimensional (3D) acquisition of 3D image data of the region of interest of the subject, wherein the protocol optimizer is configured to reduce a number of scans for each contrast that is required by the patient specific clinical indication over the region of interest along multiple planes.

PREMATURE HEARTBEAT ANALYSIS

Resumen de: US20260256403A1

Systems and methods include approaches for calculating a relative timing value for respective beats associated with a rhythm classification, determining that respective relative timing values for a first set of the beats are within a first range of prematureness, and displaying time series cardiac data of the first set of the beats in a first window of a user interface.

SECURE NETWORKED RESPIRATORY THERAPY SYSTEMS

Resumen de: US20260257029A1

Methods and apparatus provide communications among respiratory therapy device (“TD”), server and intermediary (e.g., a control device (“CTLD”) for the therapy device) to improve security. More secure communication channel(s) may be established using shared secrets derived with different channels. The communications may include transmitting therapy data from TD to server for authentication. The CTLD may receive the data and a nonce from a server. The CTLD receives from the TD a signing key dependent on the nonce and a secret shared by TD and server. The CTLD generates an authorisation code with received therapy data and the key for authentication of the data by the server upon its receipt of the code and data. The server computes (1) a key from the nonce and the secret known to TD, and (2) another authorisation code from received therapy data and the key. Data authentication may involve comparing received and computed codes.

METHOD FOR PRODUCING A NUTRACEUTICAL DELIVERY SYSTEM

Resumen de: US20260256181A1

The present invention refers to a method for producing a nutraceutical delivery system. The method comprises the steps of screen-printing a base paste, and curing the base paste. The method furthermore comprises the steps of screen-printing a first paste being separate to the base paste, and curing said first paste.

Anisotropic Materials in Medical Devices

Resumen de: US20260256592A1

0000 A system and method for improving upon an ability of a surgeon to repair traumatic bone injury using new materials, components, and structures. A structure may be used as an implant or a component of an external fixator for a fractured long bone with that structure having anisotropic and viscoelastic properties, such as through additive manufacturing techniques.

THERAPEUTIC ZONE ASSESSOR

Resumen de: US20260260729A1

0000 Systems and methods are provided for identifying therapeutic zones where there is glycemic dysfunction of a specific type that can be addressed by making strategic changes to behavior and/or therapy parameters. Systems and methods described herein evaluate large historical data sets to: identify a therapeutic zone or zones with glycemic dysfunction that are most readily addressable; quantify the glycemic impact of a plurality of different therapeutic adjustments in terms of either adjustments to historical doses or the parameters of a prospective dosing strategy to determine the highest possible improvement; and/or identify patient dosing strategies to provide therapy recommendations adapted for the patient’s preferred behavioral dosing strategy.

PATIENT-SPECIFIC VERTEBRAL IMPLANTS WITH POSITIONING FEATURES

Resumen de: US20260256591A1

0000 The present technology provides patient-specific vertebral implants. The implants can include a cage having a geometry contoured to mate with an inferior surface of a superior vertebra and a superior surface of an inferior vertebra at a first target position. The implants can also include a plate having a geometry contoured to mate with an identified anatomical structure at a second target position. The cage and plate can be coupled in a predetermined three-dimensional orientation that simultaneously permits the cage to occupy the first target position and the plate to occupy the second target position when the implant is implanted.

SYSTEMS AND METHODS FOR MANAGING, MONITORING, AND TREATING PATIENT CONDITIONS

Resumen de: US20260260724A1

0000 Systems, devices, user interfaces, and methods for managing patient conditions. A system for monitoring and/or managing a patient suffering from a brain condition may include a controller obtaining and/or storing data related to one or more monitored patient parameters contributing to the brain condition of the patient and displaying values of the one or more monitored patient parameters in trend lines over time on a user interface. The displayed trend lines may represent values of ventricular CSF volume, values of IVH volume, total ventricular volume in the brain, and/or values of other suitable parameters. The data related to the one or more monitored patient parameters may include images of the patient’s brain and/or data derived from images of the patient’s brain and/or suitable patient data.

EVALUATION METHOD BASED ON ANALYTE DATA AND AN EVALUATION SYSTEM

Resumen de: US20260256430A1

0000 Some embodiments of the disclosure describe an evaluation system based on analyte data including a memory storing a program, a display, and a processor. In some examples, the processor is configured to: receive analyte data during a predetermined time period from an object to be tested, acquire a plurality of analyte indicators different from each other based on the analyte data, normalize the plurality of analyte indicators to a predetermined range to acquire a plurality of normalized analyte indicators, plot a polygon pattern corresponding to the analyte data during the first time period as a target polygon pattern, plot a polygon pattern corresponding to the analyte data during the second time period as a reference polygon pattern, and take a line segment between a vertex and a center point as an axis, and display the target polygon pattern and the reference polygon pattern.

METHODS AND SYSTEMS FOR PREDICTING TREATMENT OUTCOMES, PATIENT SELECTION AND PERSONALIZED THERAPY USING PATIENT RESPONSE PROPERTIES TO SENSORY STIMULATION

Resumen de: US20260256407A1

In some aspects, the present disclosure describes a method of predicting an expected treatment outcome of a subject, comprising administering a gamma oscillation-inducing non-invasive sensory stimulus to the subject, measuring a response from the subject, and predicting, using a machine learning algorithm, the expected treatment outcome of the subject based at least partially on the measured response. In some aspects, the present disclosure also provides methods for personalizing gamma therapy treatment by adjusting parameters associated with the gamma oscillation-inducing non-invasive sensory stimulus based on a subject's response to the gamma oscillation-inducing non-invasive sensory stimulus.

SYSTEM AND METHOD FOR ADDITIVE MANUFACTURING USING AN OMNIDIRECTIONAL MAGNETIC MOVEMENT APPARATUS

Resumen de: US20260256701A1

0000 A process system and method for the making of articles, using an omnidirectional magnetic movement system with a transport surface and fabrication modules having a formation surface that can be transported omnidirectionally over the transport surface under the control of a movement controller. An article forming system provides process unit operations for forming articles onto the formation surface as the fabrication modules are moved asynchronously between a plurality of processing positions on the transport surface, and features a depositing device for placing a construction material onto the formation surface and one or more processing devices to form the construction material into the article.

MULTIMODAL SEIZURE SENSING

Resumen de: US20260256413A1

0000 This disclosure describes systems, apparatuses, and techniques that use of multiple sensing modalities (multimodal sensing) in parallel to improve the detection, classification, and evaluation of seizures in subjects (e.g., mammalian subjects, such as humans). In some implementations, a wearable device includes a flex sensor configured, an inertial motion unit (IMU), and a plurality of surface electromyogram (sEMG) electrodes configured to be placed approximate to a muscle of a subject. The device also includes a microprocessor. The operations performed by the microprocessor include determining multimodal movement data of the muscle, where the multimodal movement data specifies at least an acceleration associated with movement of the muscle, an angular velocity associated with movement of the muscle, and sEMG activity associated with the movement of the muscle. The operation further includes determining whether the multimodal movement data indicates a possible seizure, and provide data based on the determination for output.

THREE-DIMENSIONAL PRINTING COMPOSITION AND METHOD OF PRODUCING DENTAL PRINTED ARTICLE

Resumen de: US20260256559A1

A three-dimensional printing composition includes: a polymerizable monomer; inorganic particles; and a photopolymerization initiator. The inorganic particles are surface-treated with a compound represented by a general formula (1)(in the general formula, R1 is a hydrogen atom or a methyl group; R2 is a hydrolyzable group; R3 is a hydrocarbon group having 1 or more and 6 or less carbon atoms; p is 2 or 3; and q is an integer of 5 or more and 13 or less).

CLEAR ORTHODONTIC ALIGNER

Resumen de: US20260256547A1

0000 The present invention relates to a clear orthodontic aligner comprising at least one molecule capable of changing color or color intensity (CCM). Furthermore, the invention relates to a process for obtaining a clear orthodontic aligner by means of three-dimensional (3D) printing.

Apparatus for monitoring, regulating, or controlling fluid flow

Resumen de: AU2026216825A1

An apparatus, system and method for regulating fluid flow are disclosed. An apparatus for infusing fluid into a patient includes a housing, a tube-contact member, a rotating arm, and a tube-retention cover. The housing has an opening on a front side of the housing. The opening is sized to receive a drip chamber having an inlet tube and an outlet tube. The tube-contact member contacts one of the inlet tube and the output tube of the drip chamber when inserted into the opening. The rotating arm is coupled to the tube-contact member and is configured to rotate along an axis. The tube-retention cover is configured to close when the drip chamber is initially loaded into the opening. tube and an outlet tube. The tube-contact member contacts one of the inlet tube and ug u g t u b e a n d a n o u t l e t t u b e h e t u b e - c o n t a c t m e m b e r c o n t a c t s o n e o f t h e i n l e t t u b e a n d

SUBCUTANEOUS OUTPATIENT MANAGEMENT

Resumen de: US20260260730A1

A method of administering insulin includes receiving scheduled glucose time intervals and obtaining glucose data of a patient that includes glucose measurements, glucose times, and insulin dosages previously administered by the patient. The method also includes applying a set of filters to identify which of the glucose measurements associated with at least one of the scheduled time intervals are usable and which of the glucose measurements associated with the at least one scheduled time interval are unusable. The method also includes aggregating the glucose measurements associated with the at least one scheduled time interval identified as usable to determine a representative aggregate glucose measurement and determining a next recommended insulin dosage for the patient based on the representative aggregate glucose measurement and the insulin dosages previously administered by the patient.

CONVOLUTIONAL NEURAL NETWORK FOR IDENTIFICATION OF ANATOMICAL LANDMARK

Resumen de: US20260260476A1

A method for locating an anatomical landmark includes obtaining an ultrasound image of an anatomical area from an ultrasound imaging device and inputting the ultrasound image into a first stage of a convolutional neural network where the first stage configured to determine a key-point location of the anatomical area. The method also includes generating, for the key-point location, a cropped region of the ultrasound image and inputting the cropped region into a second stage of the convolutional neural network, where the second stage is configured to locate the anatomical landmark of the anatomical area. Then, outputting a location of the anatomical landmark.

COMBINED FACE SCANNING AND INTRAORAL SCANNING

Resumen de: US20260256546A1

A system comprises an intraoral scanner, a three-dimensional (3D) image capture device, and a computing device operatively coupled to the intraoral scanner and to the 3D image capture device. The computing device receives intraoral scan data of a dental site of a patient generated by the intraoral scanner during intraoral scanning. The computing device further receives one or more 3D images of a face of the patient generated by the 3D image capture device during the intraoral scanning, wherein the intraoral scanner is captured in the one or more 3D images. The computing device registers the one or more 3D images of the face of the patient to the first intraoral scan data based at least in part on a first position of the intraoral scanner relative to the face of the patient in the one or more 3D images.

Systems and Methods for Intraoral pH Monitoring

Resumen de: US20260256386A1

A system and method for monitoring pH of an intraoral device involves receiving the oral pH data from at least one pH sensor embedded within the intraoral device. The oral pH data is then correlated with one or more user related data to classify the oral pH data into one or more pre-defined categories indicative of a health condition. Further, the machine learning module generates feedback and/or recommendations for the user based on the classification of the oral pH data into one or more pre-defined categories. The oral pH data and/or feedback and/or recommendations are then communicated to the user and/or external device.

SYSTEMS AND METHOD FOR LINKING COSMETIC LIP COLORS TO EMOTIONS

Resumen de: US20260256395A1

A computer system receives sensor data from sensors configured to measure a user's neurophysiological response to verbal stimuli in the form of an identified emotion presented to the user and visual stimuli in the form of cosmetic colors presented to the user via a user interface; displays representations of available cosmetic colors to the user; receives user input indicating selection of a candidate cosmetic color from among the available cosmetic colors displayed; displays to the user an avatar wearing a virtual cosmetic of the candidate cosmetic color; receives user rating data responsive to display of the avatar wearing the virtual cosmetic of the candidate cosmetic color; and determines whether the candidate cosmetic color is associated with the identified emotion based on the user rating data and the sensor data. The sensors may include brain activity, electrodermal activity, eye tracking, and/or heart activity sensors.

Dissolvable Pore Reinforcement For Surface Overmolding

Resumen de: US20260256590A1

0000 A method of manufacturing an implant including additively manufacturing the implant from a first material such that the implant defines a plurality of pores. Then inserting a filler material into the pores after the implant has been manufactured. Next, overmolding the implant with a second material after the filler material has been inserted the pores, and then dissolving the filler material from the pores prior to deployment of the implant.

3D Bioprinted Model for Quantifying Neurite Outgrowth

Resumen de: US20260258350A1

A three-dimensional (3D) bioprinted model of a forebrain cortex is designed to quantify neurite outgrowth across a hydrogel bridge. The 3D bioprinted model includes two cell-laden compartments formed using a first hydrogel matrix, separated by a hydrogel bridge formed from a second, stiffer hydrogel matrix. The model may fit within standard 96-well plate formats, enabling medium-throughput screening applications. The model was validated using Alzheimer's disease forebrain cortical populations, demonstrating significant reductions in neurite outgrowth from Alzheimer's disease populations compared to controls.

ROBOTIC SURGICAL SYSTEM AND METHOD FOR USING ARTIFICIAL INTELLIGENCE TO GENERATE SIMULATION AND DECISION SUPPORT FOR TELEOPERATION

Resumen de: US20260256534A1

0000 A robotic surgical system and method for using artificial intelligence to generate simulation and decision support for teleoperation are provided. In one embodiment, the robotic surgical system provides a surgical simulation model with input about a surgical field of a patient and signals generated in response to user-manipulation of the plurality of user input devices to perform a surgical task on the patient. The surgical simulation model generates and displays a video that represents a simulated performance of the surgical task. Other embodiments are provided.

SYSTEMS AND METHODS FOR FABRICATING ORTHODONTIC RETAINERS

Resumen de: US20260256560A1

The present disclosure provides systems and methods for fabricating an orthodontic retainer comprising a retainer base. The methods may include obtaining a first digital model representing the palate and the upper teeth of a patient. The methods may include creating, based on the first digital model, a second digital model representing the retainer base and a third digital model representing a teeth shell, and creating, based on the second digital model and the third digital model, a fourth digital model representing the retainer base and the teeth shell that are connected via a connecting structure. The methods may include generating a printed assembly by printing the fourth digital model using a first curable resin material. The printed assembly may at least include the retainer base, the teeth shell, and the connecting structure. The methods may include post-processing the printed assembly to obtain the retainer base.

THERAPY FOR THE TREATMENT OF DISORDERS IN THE NERVOUS SYSTEM BY MEANS OF CLASSIFICATION OF DETECTED TREMORS THROUGH MACHINE LEARNING

Nº publicación: US20260256423A1 03/09/2026

Solicitante:

BIOTRONIK SE & CO KG [DE]
BIOTRONIK SE & Co. KG

Resumen de: US20260256423A1

A method includes receiving data for an episode stored by a medical device of a patient. The episode is associated with a period of time. The data includes an electroencephalogram or data derived from neural activity in the brain sensed by the medical device during the period of time. One or more machine learning models are applied to the data and are configured to output a respective likelihood value for each of a plurality of tremor type classifications. The method further includes, based on the application of the one or more machine learning models to the episode data, deriving, for each of the tremor type classifications, class activation data indicating varying likelihoods of the classification over the period of time; and displaying a graph of the varying likelihoods of the tremor type classifications over the period of time.